OOIR: Observatory of International Research

Papers

(The TQCC of Cytotechnology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Analysis of cell lysis for improved understanding between the shake tube and stirred tank reactor perfusion CHO cell cultures	25
A method for dissociation of oral cancer cell spheroids generated by magnetic 3D bioprinting	20
Dimethyl sulfoxide-free cryopreservation solution containing trehalose, dextran 40, and propylene glycol for therapy with human adipose tissue-derived mesenchymal stromal cells	20
BSP promotes skin wound healing by regulating the expression level of SCEL	19
The regulatory role of KIAA1429 in epithelial-mesenchymal transition in cervical cancer via mediating m6A modification of BTG2	15
Cell culture in salivary gland tumor research: molecular insights of pathogenic targets and personalized medicine	15
Construction and validation of a novel diagnostic model with palmitoylation-related genes for prostate cancer	15
Single-cell and machine learning-based analysis of the molecular mechanism of Banxia Xiexin Decoction in the treatment of gastric cancer	14
Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells	13
Frehmaglutin F and frehmaglutin H ameliorate hypoxy-induced PASMCs injury via SIRT3/HIF-1α/PKM2 signal pathway	13
Nrf2 activator Diethyl Maleate attenuates ROS mediated NLRP3 inflammasome activation in murine microglia	12
LINC01614 promoted malignant progression of stomach adenocarcinoma via miR-129-2-3p	12
FXYD6 is transcriptionally activated by KLF10 to suppress the aggressiveness of gastric cancer cells	12
Functional improvements in β-conglycinin by conjugation with pectin by the Maillard reaction	12
Dual effects of erastin on aggressive osteosarcoma cells: ferroptosis sensitization and anti-ferroptotic gene activation	11
Functional improvements in β-conglycinin by edible bioconjugation with carboxymethyl dextran	11
RNA sequencing identifies MAP1A and PTTG1 as predictive genes of aging CD264+ human mesenchymal stem cells at an early passage	10
Development of a cell line from skeletal trunk muscle of the fish Labeo rohita	10
Resveratrol inhibits TRAF6/PTCH/SMO signal and regulates prostate cancer progression	9
Effect of combined blue light and 5-ALA on mitochondrial functions and cellular responses in B16F1 melanoma and HaCaT cells	9
Current opinion on pluripotent stem cell technology in Gaucher's disease: challenges and future prospects	9
Silencing of LINC01278 promotes sensitivity of non-small cell lung cancer cells to osimertinib by targeting miR-324-3p/ZFX axis	9
CXCL1 promotes diabetic foot ulcer through activation of the TNF-α signaling pathway	9
cPLA2α on the influence of Th17 and its role in the formation of liver fibrosis	9
3D models to study therapy-induced senescence: where do we stand now?	8

SIRT1 decreases Aβ-induced IL-1β production by suppressing NLRP3 inflammasome activation and M1 microglial polarization	8
Hypoxia-induced the upregulation of NDUFA4L2 promoted colon adenocarcinoma progression through ROS-mediated PI3K/AKT pathway	8
Protective effects of exocarpium citri grandis extract and its flavonoid components against polystyrene microplastic-induced hepatointestinal injury	8
High mobility group protein N2 inhibits the progression of hepatocellular carcinoma and the related molecular mechanisms	8
Anti-arthritic and antioxidant potential of Citrus medica L. fruit extract in freund’s complete adjuvant-induced wistar rats	8
Degranulation of RBL-2H3 rat basophilic leukemia cells is synergistically inhibited by combined treatment with nobiletin and lactoferrin	8
Understanding cytotoxicity induction by plumbagin in pancreatic ductal adenocarcinoma using network pharmacology, bioinformatic and in-vitro study	8
BAP1-mediated ubiquitination inhibition and CAS6/AXL signaling activation in bladder cancer progression	7
Correction: Protective effects of lidocaine on polycystic ovary syndrome through modulating ovarian granulosa cell physiology via PI3K/AKT/mTOR pathway	7
Exosomes derived from human umbilical cord blood mesenchymal stem cells protect against blue light-induced damage to retinal pigment epithelial cells by inhibiting FGF2 expression	7
Three-dimensional mesenchymal stromal cells spheroids generated by RGD-induced self-assembly technique for tissue engineering	7
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim	7
N1-methylpseudouridine-incorporated mRNA enhances exogenous protein expression and suppresses immunogenicity in primary human fibroblast-like synoviocytes	7
Green synthesis and characterization of zinc oxide nanoparticles using Vitex negundo methanolic extract and its anticancer efficacy in colorectal cancer	7
Functional regulatory mechanisms of circRNAs in bovine adipogenesis	6
Expression profiling of circular RNAs in sepsis-induced acute gastrointestinal injury: insights into potential biomarkers and mechanisms	6
Qing-brick tea alleviates metabolic dysfunction-associated fatty liver disease: involvement of AMPK/ACC and SREBP1/FAS pathways	6
Effect of HOXB7 in promoting proliferation, invasion and migration of cervical cancer cells	6
Esketamine alleviated cardiomyocyte ferroptosis induced by oxygen–glucose deprivation/reoxygenation (OGD/R) via cyclic GMP-AMP synthase interactor	6
CircUSP36 promotes FBXO5 expression to accelerate cervical cancer progression by targeting miR-520d-5p	6
Oral cell lysates reduce osteoclastogenesis in murine bone marrow cultures	6
Cancer-associated fibroblast-derived exosomal FAM83F regulates KIF23 expression to promote the malignant progression and reduce radiosensitivity in non-small cell lung cancer	6
COL23A1 promotes tumor progression and glycolytic reprogramming in endometrial cancer via METTL14-m6A-YTHDF1 axis	6
Mechanisms of CRLF3-targeted binding to ACTR2 to promote hepatocellular carcinoma progression and effects on the immune microenvironment	6
Stable mammalian expression of His-tagged prestin in Chinese hamster ovary cells	6
Neurotrophomodulatory effect of TNF-α through NF-κB in rat cortical astrocytes	5
POM121 induces chemoresistance toward cisplatin in non-small cell lung cancer	5
Oxidative stress profile and auto-antibodies production in Tunisian patients with COVID-19	5
CRISPR-edited, cell-based future-proof meat and seafood to enhance global food security and nutrition	5
WTAP promotes laryngeal carcinoma cell progression by posttranscriptional activation of CTHRC1 in an m6A-YTHDF1-dependent way	5
Immunomodulatory effects of short-chain fatty acids in chronic obstructive pulmonary disease: rebalancing Th17/Treg axis and enhancing epithelial repair	5
Effect of different cell culture media on the production and glycosylation of a monoclonal antibody from a CHO cell line	5
KPNA2 promotes lung adenocarcinoma progression by inducing glycolysis-assisted MYC nuclear translocation	5
IBS008738, a TAZ activator, facilitates muscle repair and inhibits muscle injury in a mouse model of sport-induced injury	4
Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis	4
A novel matrine derivative, WM130, inhibits activation and movement of human hepatic stellate LX-2 cells by targeting cofilin 1	4
Identification of cell culture contamination by an unusual species of Mycoplasma related to the M. mycoides cluster	4
HOXD9 affecting glioma proliferation and invasion	4
Conditioned media from human adipose tissue-derived mesenchymal stem cells: potential effect on peripheral blood mononuclear cells in co-culture with HeLa cell line	4
Osthole attenuates airway inflammation in asthma by inhibiting the HMGB1–RAGE/TLR4–NF-κB signaling pathway	4
Evaluation of several type of chemical cryoprotectants and combination towards cryopreservation of NK cell	4
miR-675-5p regulation of autophagy by TSC2 promotes cisplatin resistance in ovarian cancer	4
Evaluation of the PrimeFlow RNA assay as a method of detection of SARS-CoV-2 single and dual Infections	4
MiR-133 promotes the multidrug resistance of acute myeloid leukemia cells (HL-60/ADR) to daunorubicin	4
circDHX33 suppresses glycolysis, malignant proliferation, and metastasis in prostate cancer by interacting with RNA-binding protein IGF2BP2 to destabilize its protein	4
SLC44A4 modulates the extracellular matrix through the PI3K/AKT signaling pathway, thereby affecting the proliferation, migration, and invasion of ovarian clear cell carcinoma (OCCC)	4
Proposal for a non-adhesive single-cell culture technology for primary hepatocytes	4
Characteristics of human induced pluripotent stem cells cultured on soft substrates	4
Yinjia pills inhibits the malignant biological behavior of HeLa cells through PKM2-medicated inhibition of JAK/STAT3 pathway	4
IGFBP7 inhibition relieves LPS induced nucleus pulposus cell injury by regulating the ERK1/2 pathway	4

USP16 promotes M2 polarization of macrophages in colorectal cancer by activating the Notch pathway via inducing the deubiquitination of E2F1	4
LINC00161 upregulated by M2-like tumor-associated macrophages promotes hepatocellular carcinoma progression by methylating HACE1 promoters	4
Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes	4
MiR-150-3p as a diagnostic biomarker and regulator of ferroptosis in preeclampsia via targeting FTH1	3
Astragalin inhibits the proliferation of high-risk HPV-positive cervical epithelial cells and attenuates malignant cervical lesions	3
Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells	3
Chemoresistance mitigation of dual drug-loaded nanoparticles with doxorubicin and curcumin	3
Animal origins free products in cell culture media: a new frontier	3
A feasibility study of different commercially available serum-free mediums to enhance lentivirus and adeno-associated virus production in HEK 293 suspension cells	3
Effects of wasp (Vespa crabro) nest extracts on virus replication of Autographa californica nuclear polyhedrosis virus on Spodoptera frugiperda cell culture	3
In vitro evaluation of cytotoxicity and release kinetics of green-synthesised Azadirachta indica silver nanoparticles	3
LncRNA NR2F1-AS1 is involved in osteogenic differentiation in fracture healing via miR-423-5p	3
Metformin inhibits subretinal fibrosis by activating Klotho by miR-126-5p	3
Serum PLAC1 levels for differential diagnosis between cervical intraepithelial neoplasia and invasive cervical cancer: a prospective observational study	3
Resolution assessment of super-resolution microscopy imaging: structural and technical dependencies for cell biology	3
Mechanism of lncRNA WARS2-IT1 promoting angiogenesis of glioma through miR-299-3P/VEGFA axis and activating PI3K/AKT signaling pathway	3
TLR agonist rMBP-NAP inhibits B16 melanoma tumor growth via induction of DCs maturation and T-cells cytotoxic response	3
Enhancement of malignant potency through lysophosphatidic acid (LPA) receptor signaling in pancreatic cancer cells under hypoxic conditions	3
The oncogenic role of SPOCK1 in lung carcinoma by promoting immune evasion and its related mechanisms	3
Protective effects of Scutellaria barbata against hepatocyte apoptosis during hepatic fibrosis progression	3
The reducing effect of TNF-α on carbonic anhydrase III gene expression in colon carcinoma and osteosarcoma cells	3
Effective methods for immobilization of non-adherent Pv11 cells while maintaining their desiccation tolerance	3
MicroRNA-106b-5p (miR-106b-5p) suppresses the proliferation and metastasis of cervical cancer cells via down-regulating fibroblast growth factor 4 (FGF4) expression	3
Exosomes from myoblasts induced by hypoxic preconditioning improved ventricular conduction by increasing Cx43 expression in hypothermia ischemia reperfusion hearts	3
A novel liphagal analog, IIIM-321, induces apoptosis in melanoma cells via autophagy modulation and PI3K/MAPK pathway inhibition	3
Cytotoxicity and potential cell death mechanisms of three new benzamidine derivatives in esophageal squamous cell carcinoma cells using in vitro and in silico approaches	3
Investigation of scaffold manufacturing conditions for 3-dimensional culture of myogenic cell line derived from black sea bream (Acanthopagrus schlegelii)	3
The study on bone marrow mesenchymal stem cell-derived extracellular matrix promoting the repair of damaged chondrocytes by regulating the Notch1/RBPJ pathway	3
Rehmannioside A: a therapeutic agent for cerebral ischaemia-reperfusion injury via p38 MAPK pathway modulation	3
Alcohol consumption affects macrophage polarization and promotes the malignant behavior of gastric cancer cells by regulating the miR-29c-3p/COL1A1 signaling pathway	3
Aging and cell expansion enhance microRNA diversity in small extracellular vesicles produced from human adipose-derived stem cells	3
Exploring the mechanism of Epimedium in treating diabetic nephropathy based on network pharmacology and experimental validation study	3
Apigenin inhibits liver cancer via mitochondrial apoptosis and Th1/Th2 balance regulation	3
E2F8—TPX2 axis regulates glycolysis and angiogenesis to promote progression and reduce chemosensitivity of liver cancer	3
Isolating cancer stem cells in breast cancer models: a study of CD marker expression and Rhodamine 123 as predictors of chemoresistance	3
New mechanism of miR-34a-5p in regulating the biological behavior of osteosarcoma by targeting FoxM1	3
The Inhibition of CDK4/6 regulates the activity of multidrug resistance pumps in glioblastoma	3
Genes and proteins expression profile of 2D vs 3D cancer models: a comparative analysis for better tumor insights	3