OOIR: Observatory of International Research

Papers

(The TQCC of Cytotechnology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Analysis of cell lysis for improved understanding between the shake tube and stirred tank reactor perfusion CHO cell cultures	27
Dimethyl sulfoxide-free cryopreservation solution containing trehalose, dextran 40, and propylene glycol for therapy with human adipose tissue-derived mesenchymal stromal cells	20
BSP promotes skin wound healing by regulating the expression level of SCEL	20
Construction and validation of a novel diagnostic model with palmitoylation-related genes for prostate cancer	19
The regulatory role of KIAA1429 in epithelial-mesenchymal transition in cervical cancer via mediating m6A modification of BTG2	15
Cell culture in salivary gland tumor research: molecular insights of pathogenic targets and personalized medicine	15
Single-cell and machine learning-based analysis of the molecular mechanism of Banxia Xiexin Decoction in the treatment of gastric cancer	15
Silencing CDKN2B-AS1 alleviates cognitive impairment caused by ischemic stroke by upregulating miR-140-3p levels	14
A method for dissociation of oral cancer cell spheroids generated by magnetic 3D bioprinting	13
Frehmaglutin F and frehmaglutin H ameliorate hypoxy-induced PASMCs injury via SIRT3/HIF-1α/PKM2 signal pathway	13
Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells	13
FXYD6 is transcriptionally activated by KLF10 to suppress the aggressiveness of gastric cancer cells	12
Functional improvements in β-conglycinin by conjugation with pectin by the Maillard reaction	12
Nrf2 activator Diethyl Maleate attenuates ROS mediated NLRP3 inflammasome activation in murine microglia	12
LINC01614 promoted malignant progression of stomach adenocarcinoma via miR-129-2-3p	12
Dual effects of erastin on aggressive osteosarcoma cells: ferroptosis sensitization and anti-ferroptotic gene activation	11
Development of a cell line from skeletal trunk muscle of the fish Labeo rohita	10
Functional improvements in β-conglycinin by edible bioconjugation with carboxymethyl dextran	10
RNA sequencing identifies MAP1A and PTTG1 as predictive genes of aging CD264+ human mesenchymal stem cells at an early passage	10
Anti-arthritic and antioxidant potential of Citrus medica L. fruit extract in freund’s complete adjuvant-induced wistar rats	9
Effect of combined blue light and 5-ALA on mitochondrial functions and cellular responses in B16F1 melanoma and HaCaT cells	9
cPLA2α on the influence of Th17 and its role in the formation of liver fibrosis	9
Silencing of LINC01278 promotes sensitivity of non-small cell lung cancer cells to osimertinib by targeting miR-324-3p/ZFX axis	9
Current opinion on pluripotent stem cell technology in Gaucher's disease: challenges and future prospects	9
3D models to study therapy-induced senescence: where do we stand now?	8

CXCL1 promotes diabetic foot ulcer through activation of the TNF-α signaling pathway	8
Degranulation of RBL-2H3 rat basophilic leukemia cells is synergistically inhibited by combined treatment with nobiletin and lactoferrin	8
SIRT1 decreases Aβ-induced IL-1β production by suppressing NLRP3 inflammasome activation and M1 microglial polarization	8
Protective effects of exocarpium citri grandis extract and its flavonoid components against polystyrene microplastic-induced hepatointestinal injury	8
Understanding cytotoxicity induction by plumbagin in pancreatic ductal adenocarcinoma using network pharmacology, bioinformatic and in-vitro study	8
Hypoxia-induced the upregulation of NDUFA4L2 promoted colon adenocarcinoma progression through ROS-mediated PI3K/AKT pathway	8
Resveratrol inhibits TRAF6/PTCH/SMO signal and regulates prostate cancer progression	8
xCELLigence™ RTCA system in cancer biology: innovations in real-time functional profiling	8
Co-Culture of nasopharyngeal carcinoma cells and fibroblasts induces altered integrin expression associated with 3D structural formation	8
BAP1-mediated ubiquitination inhibition and CAS6/AXL signaling activation in bladder cancer progression	7
Correction: Protective effects of lidocaine on polycystic ovary syndrome through modulating ovarian granulosa cell physiology via PI3K/AKT/mTOR pathway	7
COL23A1 promotes tumor progression and glycolytic reprogramming in endometrial cancer via METTL14-m6A-YTHDF1 axis	7
Three-dimensional mesenchymal stromal cells spheroids generated by RGD-induced self-assembly technique for tissue engineering	7
Exosomes derived from human umbilical cord blood mesenchymal stem cells protect against blue light-induced damage to retinal pigment epithelial cells by inhibiting FGF2 expression	7
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim	7
Effect of HOXB7 in promoting proliferation, invasion and migration of cervical cancer cells	7
High mobility group protein N2 inhibits the progression of hepatocellular carcinoma and the related molecular mechanisms	7
Green synthesis and characterization of zinc oxide nanoparticles using Vitex negundo methanolic extract and its anticancer efficacy in colorectal cancer	7
Esketamine alleviated cardiomyocyte ferroptosis induced by oxygen–glucose deprivation/reoxygenation (OGD/R) via cyclic GMP-AMP synthase interactor	7
Functional regulatory mechanisms of circRNAs in bovine adipogenesis	7
N1-methylpseudouridine-incorporated mRNA enhances exogenous protein expression and suppresses immunogenicity in primary human fibroblast-like synoviocytes	6
Oral cell lysates reduce osteoclastogenesis in murine bone marrow cultures	6
WTAP promotes laryngeal carcinoma cell progression by posttranscriptional activation of CTHRC1 in an m6A-YTHDF1-dependent way	6
Cancer-associated fibroblast-derived exosomal FAM83F regulates KIF23 expression to promote the malignant progression and reduce radiosensitivity in non-small cell lung cancer	6
Mechanisms of CRLF3-targeted binding to ACTR2 to promote hepatocellular carcinoma progression and effects on the immune microenvironment	6
CircUSP36 promotes FBXO5 expression to accelerate cervical cancer progression by targeting miR-520d-5p	6
The role of hypoxia in the regulation of serotonergic signaling: an investigation of HTR1B and TPH-1 expression in colorectal cancer and C. elegans models	6
Expression profiling of circular RNAs in sepsis-induced acute gastrointestinal injury: insights into potential biomarkers and mechanisms	6
POM121 induces chemoresistance toward cisplatin in non-small cell lung cancer	6
KPNA2 promotes lung adenocarcinoma progression by inducing glycolysis-assisted MYC nuclear translocation	5
Effect of different cell culture media on the production and glycosylation of a monoclonal antibody from a CHO cell line	5
CRISPR-edited, cell-based future-proof meat and seafood to enhance global food security and nutrition	5
Stable mammalian expression of His-tagged prestin in Chinese hamster ovary cells	5
Immunomodulatory effects of short-chain fatty acids in chronic obstructive pulmonary disease: rebalancing Th17/Treg axis and enhancing epithelial repair	5
Qing-brick tea alleviates metabolic dysfunction-associated fatty liver disease: involvement of AMPK/ACC and SREBP1/FAS pathways	5
Neurotrophomodulatory effect of TNF-α through NF-κB in rat cortical astrocytes	5
miR-675-5p regulation of autophagy by TSC2 promotes cisplatin resistance in ovarian cancer	4
Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis	4
Evaluation of the PrimeFlow RNA assay as a method of detection of SARS-CoV-2 single and dual Infections	4
A novel matrine derivative, WM130, inhibits activation and movement of human hepatic stellate LX-2 cells by targeting cofilin 1	4
Osthole attenuates airway inflammation in asthma by inhibiting the HMGB1–RAGE/TLR4–NF-κB signaling pathway	4
Resolution assessment of super-resolution microscopy imaging: structural and technical dependencies for cell biology	4
IBS008738, a TAZ activator, facilitates muscle repair and inhibits muscle injury in a mouse model of sport-induced injury	4
Characteristics of human induced pluripotent stem cells cultured on soft substrates	4
Oxidative stress profile and auto-antibodies production in Tunisian patients with COVID-19	4
Correction: Viscum coloratum (Kom.) Nakai inhibits osteoclastogenesis in RANKL-induced osteoclast differentiation through the PI3K/AKT/mTOR pathway	4
MiR-133 promotes the multidrug resistance of acute myeloid leukemia cells (HL-60/ADR) to daunorubicin	4
A feasibility study of different commercially available serum-free mediums to enhance lentivirus and adeno-associated virus production in HEK 293 suspension cells	4
LINC00161 upregulated by M2-like tumor-associated macrophages promotes hepatocellular carcinoma progression by methylating HACE1 promoters	4
Evaluation of several type of chemical cryoprotectants and combination towards cryopreservation of NK cell	4

Yinjia pills inhibits the malignant biological behavior of HeLa cells through PKM2-medicated inhibition of JAK/STAT3 pathway	4
Exploring the laxative effects of emodin on constipation through chloride channel activation	4
circDHX33 suppresses glycolysis, malignant proliferation, and metastasis in prostate cancer by interacting with RNA-binding protein IGF2BP2 to destabilize its protein	4
IGFBP7 inhibition relieves LPS induced nucleus pulposus cell injury by regulating the ERK1/2 pathway	4
Identification of cell culture contamination by an unusual species of Mycoplasma related to the M. mycoides cluster	4
Proposal for a non-adhesive single-cell culture technology for primary hepatocytes	4
Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells	3
Aging and cell expansion enhance microRNA diversity in small extracellular vesicles produced from human adipose-derived stem cells	3
PX-12 exhibits cytotoxic and anti-migration effects in colorectal cancer cells under Hypoxia-like conditions induced by Dimethyloxalylglycine	3
The oncogenic role of SPOCK1 in lung carcinoma by promoting immune evasion and its related mechanisms	3
Resveratrol coordinates apoptosis and autophagy in hepatocellular carcinoma cells via p53 acetylation: An integrative network pharmacology and experimental validation study	3
Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes	3
Animal origins free products in cell culture media: a new frontier	3
Effects of wasp (Vespa crabro) nest extracts on virus replication of Autographa californica nuclear polyhedrosis virus on Spodoptera frugiperda cell culture	3
Exosomes from myoblasts induced by hypoxic preconditioning improved ventricular conduction by increasing Cx43 expression in hypothermia ischemia reperfusion hearts	3
Metformin inhibits subretinal fibrosis by activating Klotho by miR-126-5p	3
A novel liphagal analog, IIIM-321, induces apoptosis in melanoma cells via autophagy modulation and PI3K/MAPK pathway inhibition	3
Apigenin inhibits liver cancer via mitochondrial apoptosis and Th1/Th2 balance regulation	3
Mechanism of lncRNA WARS2-IT1 promoting angiogenesis of glioma through miR-299-3P/VEGFA axis and activating PI3K/AKT signaling pathway	3
The study on bone marrow mesenchymal stem cell-derived extracellular matrix promoting the repair of damaged chondrocytes by regulating the Notch1/RBPJ pathway	3
Rehmannioside A: a therapeutic agent for cerebral ischaemia-reperfusion injury via p38 MAPK pathway modulation	3
Effective methods for immobilization of non-adherent Pv11 cells while maintaining their desiccation tolerance	3
Exploring the mechanism of Epimedium in treating diabetic nephropathy based on network pharmacology and experimental validation study	3
USP16 promotes M2 polarization of macrophages in colorectal cancer by activating the Notch pathway via inducing the deubiquitination of E2F1	3
Conditioned media from human adipose tissue-derived mesenchymal stem cells: potential effect on peripheral blood mononuclear cells in co-culture with HeLa cell line	3
Genes and proteins expression profile of 2D vs 3D cancer models: a comparative analysis for better tumor insights	3
Cytotoxicity and potential cell death mechanisms of three new benzamidine derivatives in esophageal squamous cell carcinoma cells using in vitro and in silico approaches	3
Isolating cancer stem cells in breast cancer models: a study of CD marker expression and Rhodamine 123 as predictors of chemoresistance	3
Enhancement of malignant potency through lysophosphatidic acid (LPA) receptor signaling in pancreatic cancer cells under hypoxic conditions	3
The Inhibition of CDK4/6 regulates the activity of multidrug resistance pumps in glioblastoma	3
Chemoresistance mitigation of dual drug-loaded nanoparticles with doxorubicin and curcumin	3
MiR-150-3p as a diagnostic biomarker and regulator of ferroptosis in preeclampsia via targeting FTH1	3
SLC44A4 modulates the extracellular matrix through the PI3K/AKT signaling pathway, thereby affecting the proliferation, migration, and invasion of ovarian clear cell carcinoma (OCCC)	3
In vitro evaluation of cytotoxicity and release kinetics of green-synthesised Azadirachta indica silver nanoparticles	3
TLR agonist rMBP-NAP inhibits B16 melanoma tumor growth via induction of DCs maturation and T-cells cytotoxic response	3
Protective effects of Scutellaria barbata against hepatocyte apoptosis during hepatic fibrosis progression	3
HOXD9 affecting glioma proliferation and invasion	3
The reducing effect of TNF-α on carbonic anhydrase III gene expression in colon carcinoma and osteosarcoma cells	3
Astragalin inhibits the proliferation of high-risk HPV-positive cervical epithelial cells and attenuates malignant cervical lesions	3
LncRNA NR2F1-AS1 is involved in osteogenic differentiation in fracture healing via miR-423-5p	3
New mechanism of miR-34a-5p in regulating the biological behavior of osteosarcoma by targeting FoxM1	3
Serum PLAC1 levels for differential diagnosis between cervical intraepithelial neoplasia and invasive cervical cancer: a prospective observational study	3
E2F8—TPX2 axis regulates glycolysis and angiogenesis to promote progression and reduce chemosensitivity of liver cancer	3
Investigation of scaffold manufacturing conditions for 3-dimensional culture of myogenic cell line derived from black sea bream (Acanthopagrus schlegelii)	3
Alcohol consumption affects macrophage polarization and promotes the malignant behavior of gastric cancer cells by regulating the miR-29c-3p/COL1A1 signaling pathway	3