OOIR: Observatory of International Research

Papers

(The median citation count of Cytotechnology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Circ-IGF1R plays a significant role in psoriasis via regulation of a miR-194-5p/CDK1 axis	24
Analysis of cell lysis for improved understanding between the shake tube and stirred tank reactor perfusion CHO cell cultures	16
The regulatory role of KIAA1429 in epithelial-mesenchymal transition in cervical cancer via mediating m6A modification of BTG2	14
BSP promotes skin wound healing by regulating the expression level of SCEL	13
Dimethyl sulfoxide-free cryopreservation solution containing trehalose, dextran 40, and propylene glycol for therapy with human adipose tissue-derived mesenchymal stromal cells	13
Cell culture in salivary gland tumor research: molecular insights of pathogenic targets and personalized medicine	13
miR-200b-3p alleviates TNF-α-induced apoptosis and inflammation of intestinal epithelial cells and ulcerative colitis progression in rats via negatively regulating KHDRBS1	13
Acetyl l-carnitine protects adipose-derived stem cells against serum-starvation: regulation on the network composed of reactive oxygen species, autophagy, apoptosis and senescence	12
Development of a cell line from skeletal trunk muscle of the fish Labeo rohita	12
Black carrot anthocyanins exhibit neuroprotective effects against MPP+ induced cell death and cytotoxicity via inhibition of oxidative stress mediated apoptosis	12
Nrf2 activator Diethyl Maleate attenuates ROS mediated NLRP3 inflammasome activation in murine microglia	11
Protective effects of liquiritin on polycystic ovary syndrome through modulating ovarian granulosa cell proliferation and apoptosis via miR-206/PI3K/AKT pathway	10
Pulmonary AngII promotes LPS-induced lung inflammation by regulating microRNA-143	10
Functional improvements in β-conglycinin by edible bioconjugation with carboxymethyl dextran	10
cPLA2α on the influence of Th17 and its role in the formation of liver fibrosis	10
FXYD6 is transcriptionally activated by KLF10 to suppress the aggressiveness of gastric cancer cells	10
Silencing of circHIPK3 hampers platelet-derived growth factor-induced proliferation and migration in airway smooth muscle cells through the miR-375/MMP-16 axis	9
RNA sequencing identifies MAP1A and PTTG1 as predictive genes of aging CD264+ human mesenchymal stem cells at an early passage	9
Hypoxia-induced the upregulation of NDUFA4L2 promoted colon adenocarcinoma progression through ROS-mediated PI3K/AKT pathway	9
Towards the standardization of methods of tissue processing for the isolation of mesenchymal stromal cells for clinical use	8
Current opinion on pluripotent stem cell technology in Gaucher's disease: challenges and future prospects	8
Degranulation of RBL-2H3 rat basophilic leukemia cells is synergistically inhibited by combined treatment with nobiletin and lactoferrin	8
The roles of HOXB8 through activating Wnt/β-catenin and STAT3 signaling pathways in the growth, migration and invasion of ovarian cancer cells	8
Effect of combined blue light and 5-ALA on mitochondrial functions and cellular responses in B16F1 melanoma and HaCaT cells	8
Age-related functional decline of human B cells	8

Resveratrol inhibits TRAF6/PTCH/SMO signal and regulates prostate cancer progression	8
Silencing of LINC01278 promotes sensitivity of non-small cell lung cancer cells to osimertinib by targeting miR-324-3p/ZFX axis	8
N1-methylpseudouridine-incorporated mRNA enhances exogenous protein expression and suppresses immunogenicity in primary human fibroblast-like synoviocytes	7
Exosomes derived from human umbilical cord blood mesenchymal stem cells protect against blue light-induced damage to retinal pigment epithelial cells by inhibiting FGF2 expression	7
High mobility group protein N2 inhibits the progression of hepatocellular carcinoma and the related molecular mechanisms	7
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim	7
Cancer-associated fibroblast-derived exosomal FAM83F regulates KIF23 expression to promote the malignant progression and reduce radiosensitivity in non-small cell lung cancer	7
Esketamine alleviated cardiomyocyte ferroptosis induced by oxygen–glucose deprivation/reoxygenation (OGD/R) via cyclic GMP-AMP synthase interactor	7
Oral cell lysates reduce osteoclastogenesis in murine bone marrow cultures	6
WTAP promotes laryngeal carcinoma cell progression by posttranscriptional activation of CTHRC1 in an m6A-YTHDF1-dependent way	6
CRISPR-edited, cell-based future-proof meat and seafood to enhance global food security and nutrition	6
PBX1 attenuates 6-OHDA-induced oxidative stress and apoptosis and affects PINK1/PARKIN expression in dopaminergic neurons via FOXA1	6
IBS008738, a TAZ activator, facilitates muscle repair and inhibits muscle injury in a mouse model of sport-induced injury	6
Expression profiling of circular RNAs in sepsis-induced acute gastrointestinal injury: insights into potential biomarkers and mechanisms	6
Effect of different cell culture media on the production and glycosylation of a monoclonal antibody from a CHO cell line	6
Neurotrophomodulatory effect of TNF-α through NF-κB in rat cortical astrocytes	6
Yinjia pills inhibits the malignant biological behavior of HeLa cells through PKM2-medicated inhibition of JAK/STAT3 pathway	5
ECRG4 acts as a tumor suppressor in nasopharyngeal carcinoma by suppressing the AKT/GSK3β/β-catenin signaling pathway	5
Conditioned media from human adipose tissue-derived mesenchymal stem cells: potential effect on peripheral blood mononuclear cells in co-culture with HeLa cell line	5
Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes	5
Evaluation of the PrimeFlow RNA assay as a method of detection of SARS-CoV-2 single and dual Infections	5
Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis	5
A novel matrine derivative, WM130, inhibits activation and movement of human hepatic stellate LX-2 cells by targeting cofilin 1	5
Oxidative stress profile and auto-antibodies production in Tunisian patients with COVID-19	5
Effect of short-time treatment with TNF-α on stem cell activity and barrier function in enteroids	5
Proposal for a non-adhesive single-cell culture technology for primary hepatocytes	5
Identification of cell culture contamination by an unusual species of Mycoplasma related to the M. mycoides cluster	5
MiR-133 promotes the multidrug resistance of acute myeloid leukemia cells (HL-60/ADR) to daunorubicin	4
The study on bone marrow mesenchymal stem cell-derived extracellular matrix promoting the repair of damaged chondrocytes by regulating the Notch1/RBPJ pathway	4
Lotus root extract inhibits skin damage through suppression of collagenase production in vitro	4
hsa_circ_0000218/hsa-miR-139-3p/SOX4 regulatory feedback circuit influences the proliferation and apoptosis of gastric cancer cells	4
Astragalin inhibits the proliferation of high-risk HPV-positive cervical epithelial cells and attenuates malignant cervical lesions	4
A feasibility study of different commercially available serum-free mediums to enhance lentivirus and adeno-associated virus production in HEK 293 suspension cells	4
Aging and cell expansion enhance microRNA diversity in small extracellular vesicles produced from human adipose-derived stem cells	4
Effective methods for immobilization of non-adherent Pv11 cells while maintaining their desiccation tolerance	4
TLR agonist rMBP-NAP inhibits B16 melanoma tumor growth via induction of DCs maturation and T-cells cytotoxic response	4
Development of a novel feeding regime for large scale production of human umbilical cord mesenchymal stem/stromal cells	4
Paramylon extracted from Euglena gracilis EOD-1 augmented the expression of SIRT1	4
LINC00161 upregulated by M2-like tumor-associated macrophages promotes hepatocellular carcinoma progression by methylating HACE1 promoters	4
circDHX33 suppresses glycolysis, malignant proliferation, and metastasis in prostate cancer by interacting with RNA-binding protein IGF2BP2 to destabilize its protein	4
Surface coating materials regulates the attachment and differentiation of mouse embryonic stem cell derived embryoid bodies into mesoderm at culture conditions	4
Exploring the mechanism of Epimedium in treating diabetic nephropathy based on network pharmacology and experimental validation study	4
New mechanism of miR-34a-5p in regulating the biological behavior of osteosarcoma by targeting FoxM1	3
Investigation of scaffold manufacturing conditions for 3-dimensional culture of myogenic cell line derived from black sea bream (Acanthopagrus schlegelii)	3
Animal origins free products in cell culture media: a new frontier	3
E2F8—TPX2 axis regulates glycolysis and angiogenesis to promote progression and reduce chemosensitivity of liver cancer	3
Exosomes from myoblasts induced by hypoxic preconditioning improved ventricular conduction by increasing Cx43 expression in hypothermia ischemia reperfusion hearts	3
Reproductive stage- and season-dependent culture characteristics of enriched caprine male germline stem cells	3
Protective effects of Scutellaria barbata against hepatocyte apoptosis during hepatic fibrosis progression	3
Effects of wasp (Vespa crabro) nest extracts on virus replication of Autographa californica nuclear polyhedrosis virus on Spodoptera frugiperda cell culture	3

Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells	3
Metformin inhibits subretinal fibrosis by activating Klotho by miR-126-5p	3
Genes and proteins expression profile of 2D vs 3D cancer models: a comparative analysis for better tumor insights	3
Exosomal circ_PTPRA inhibits tumorigenesis and promotes radiosensitivity in colorectal cancer by enriching the level of SMAD4 via competitively binding to miR-671-5p	3
Differential in vitro anti-leukemic activity of resveratrol combined with serine palmitoyltransferase inhibitor myriocin in FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) carrying A	3
miR-141-3p inhibited BPA-induced proliferation and migration of lung cancer cells through PTGER4	2
FGF21 relieves calcium oxalate-induced cell injury, apoptosis, oxidative damage and ferroptosis of renal tubular epithelial cells through activating Nrf2 signaling pathway	2
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT	2
Obtusifolin inhibits podocyte apoptosis by inactivating NF-κB signaling in acute kidney injury	2
OCT4, SOX2 and NANOG co-regulate glycolysis and participate in somatic induced reprogramming	2
Activation of the Nrf2/HO-1 axis by glutaredoxin 2 overexpression antagonizes vascular endothelial cell oxidative injury and inflammation under LPS exposure	2
Correction to: Platelet-derived growth factor-BB induces pulmonary venous smooth muscle cells proliferation by upregulating calcium sensing receptor under hypoxic conditions	2
Reduced immunogenicity and endowed antimicrobial activity in β-lactoglobulin by preparing edible bioconjugate	2
Correction: Development of scaffold-free tissue-engineered constructs derived from mesenchymal stem cells with serum-free media for cartilage repair and long-term preservation	2
Expression and clinical significance of IGF-1 and PDGF in aqueous humor and serum of diabetic patients with visually significant cataract	2
Targeting a novel circITCH/miR-421/BTG1 axis is effective to suppress the malignant phenotypes in hepatocellular carcinoma (HCC) cells	2
Mechanism of microRNA-124-3p targeting calpain-1 to affect the function of intervertebral disc nucleus pulposus cells	2
Investigation of the neuroprotective and neuritogenic effects of halotolerant Penicillium flavigenum-derived sorbicillin-like compounds on PC-12 Adh cells	2
Functional improvements in β-conglycinin by preparing edible bioconjugates with ε-polylysine and dextran	2
Taraxasterol suppresses cell proliferation and boosts cell apoptosis via inhibiting GPD2-mediated glycolysis in gastric cancer	2
The secretome of microglia induced by IL-4 of IFN-γ differently regulate proliferation, differentiation and survival of adult neural stem/progenitor cell by targeting the PI3K-Akt pathway	2
Optimization of adaptation parameters from adhesion cell culture in serum-containing media to suspension in chemically defined media by superlative box design	2
Green synthesis of silver nanoparticles using Amomum nilgiricum leaf extracts: preparation, physicochemical characterization and ameliorative effect against human cancer cell lines	2
Evaluation of the Ki-67 labeling index on immediate pre-ablation biopsies as a predictive biomarker of local recurrence of colorectal cancer liver metastases	2
Protective effect of selenium on vincristine-induced peripheral neuropathy in PC12 cell line	2
Exosome-mediated circGMPS facilitates the development of gastric cancer cells through miR-144-3p/PUM1	2
Cytotoxic mechanism of tioconazole involves cell cycle arrest at mitosis through inhibition of microtubule assembly	2
Dietary Zinc activates the Nrf2 signaling pathway to inhibit pyroptosis and attenuate the lung inflammatory response in COPD	2
Docetaxel treatment together with CTLA-4 knockdown enhances reduction of cell viability and amplifies apoptosis stimulation of MCF-7 breast cancer cells	2
MiR-4763-3p accelerates lipopolysaccharide-induced cardiomyocyte apoptosis and inflammatory response by targeting IL10RA	2
Substrate coated with autologous decellularized extracellular matrix facilitates in vitro spreading of spheroid from adipose-derived stem cells through regulating ERK1/2-MMP2/9 pathway	2
MicroRNA-106b-5p (miR-106b-5p) suppresses the proliferation and metastasis of cervical cancer cells via down-regulating fibroblast growth factor 4 (FGF4) expression	2
H3K27 acetylation-induced FSTL1 upregulation by P300/RUNX1 co-activation exacerbated autophagy-mediated neuronal damage and NF-κB-stimulated inflammation in Alzheimer’s disease	2
Isolation of holostane-type saponins from the black sea cucumber Holothuria atra and evaluating their anti-allergic activity: in vitro and in silico study	2
Prdm12 regulates inhibitory neuron differentiation in mouse embryonal carcinoma cells	1
PRPF19 functions in DNA damage repair and gemcitabine sensitivity via regulating DDB1 in bladder cancer cells	1
Identification of plasma exosomal microRNAs and bioinformatics analysis of the microRNA-messenger RNA regulatory pathways in mice with status epilepticus	1
Circ_0137287 suppresses cell tumroigenesis and aerobic glycolysis in papillary thyroid carcinoma through miR-183-5p/PPP2R2A axis	1
Effects of ubiquitous chromatin opening element (UCOE) on recombinant anti-TNFα antibody production and expression stability in CHO-DG44 cells	1
Advancing brain tumor therapy: unveiling the potential of PROTACs for targeted protein degradation	1
Taraxasterol mediated autophagy inhibition in pancreatic encephalopathy involves its regulation on L1 cell adhesion molecule	1
Functional improvements in β-lactoglobulin by conjugation with high methoxy pectin by the Maillard reaction	1
KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation	1
The mechanism of curcumin protecting against IL-1β-induced oxidative stress and inflammation in chondrocytes via the Bmp2/Smad5/Runx2 pathway	1
Effect of pH on antitumor activity of Chinese cobra (Naja atra) cytotoxin-XII	1
Immortalization of cells derived from domestic dogs through expressing mutant cyclin-dependent kinase 4, cyclin D1, and telomerase reverse transcriptase	1
A simplified in vitro disease-mimicking culture system can determine the angiogenic effect of medicines on vascular diseases	1
KLF7 reverses ox-LDL-induced ferroptosis in HMEC-1 cells through transcriptionally activating ALKBH5 to inhibit the m6A modification of ACSL4	1
Protective effects of lidocaine on polycystic ovary syndrome through modulating ovarian granulosa cell physiology via PI3K/AKT/mTOR pathway	1
KDM1A-mediated ZFP64 demethylation activates CENPL to promote epithelial ovarian cancer progression	1
Correction to: LncRNA ARAP1-AS1 aggravates the malignant phenotypes of ovarian cancer cells through sponging miR-4735-3p to enhance PLAGL2 expression	1
AKT activation participates in Fascin-1-induced EMT in hepatoma cells	1
Etomidate suppresses proliferation, migration, invasion, and glycolysis in esophageal cancer cells via PI3K/AKT pathway inhibition	1
Functional improvements in β-conglycinin by preparing bioconjugates with carboxymethyl cellulose	1
Mechanical strain regulates osteoclastogenesis via modulating the PTEN/PI3K/Akt signal pathway through miR-21	1
miR-17-5p accelerates cervical cancer cells migration and invasion via the TIMP2/MMPs signaling cascade	1
Proanthocyanidin B2 alleviates Pg.LPS-induced RAW264.7 cellular inflammation and oxidative stress via PI3K/Akt/NFkB pathway	1
The roles of melatonin and potassium channels in relaxation response to ang 1–7 in diabetic rat isolated aorta	1
The m6A reader IGF2BP1 manipulates BUB1B expression to affect malignant behaviors, stem cell properties, and immune resistance of non-small-cell lung cancer stem cells	1
Identification of differentially expressed miRNAs and mRNAs associated with the regulation of breast cancer via in silico and in vitro methods	1
Fermented plant product (FPP) suppresses immediate hypersensitivity reactions with impaired high-affinity IgE receptor (FcεRI) signaling	1
Enhancing monoclonal antibody production efficiency using CHO-MK cells and specific media in a conventional fed-batch culture	1
Application of a modified lactate dehydrogenase assay to evaluate the viability of cells cultured on 3D scaffolds when commonly used assays fail	1
Molecular chaperones HSP40, HSP70, STIP1, and HSP90 are involved in stabilization of Cx43	1
LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA	1