Cardiovascular Drugs and Therapy

Papers
(The TQCC of Cardiovascular Drugs and Therapy is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Vaccine Targeting Alpha 1D-Adrenergic Receptor Improved Metabolic Syndrome in Mice65
RELM-β Augmented Hypoxia-Induced Pulmonary Hypertension Through Interacting with GIPC1, OR1N1 and CLIC452
MicroRNA-205-5p: A Potential Therapeutic Target for Combating Unstable Atherogenesis?38
Immediate Versus Staged Complete Revascularization in Patients Presenting with Acute Coronary Syndrome and Multivessel Coronary Disease Without Cardiac Shock: A Study-Level Meta-analysis of Randomized34
Efficacy and Safety of Inclisiran in Patients with Polyvascular Disease: Pooled, Post Hoc Analysis of the ORION-9, ORION-10, and ORION-11 Phase 3 Randomized Controlled Trials34
Correction to: Hemodynamic Response to Oral Vasodilator Therapy in Systemic Sclerosis‑Related Pulmonary Hypertension34
Early in-hospital use of SGLT2i in heart failure patients with ischemic etiology33
Targeting SIRT3 in Diabetic Cardiomyopathy: Mechanism-Based Therapeutic Strategies29
Opioid-Sparing Effects of Erector Spinae Plane Block in Off-Pump Coronary Artery Bypass Grafting with Median Sternotomy: A Randomized Controlled Trial28
The Infarct-Limiting Effect of Remote Ischemic Conditioning in Rats Is Not Affected by Aspirin26
Association of Angiotensin Receptor-Neprilysin Inhibitors Use and Better Cardiorenal Outcomes in Patients With Heart Failure and Acute Kidney Disease24
Impact of CYP2C19 Genotype on Efficacy and Safety of Clopidogrel-based Antiplatelet Therapy in Stroke or Transient Ischemic Attack Patients: An Updated Systematic Review and Meta-analysis of Non-East 23
Association Between the Magnitude of Glycemic Control and Body Weight Loss With GLP-1 Receptor Agonists and Risk of Atherosclerotic Cardiovascular Disease: A Systematic Review and Meta-analyses of Ran23
Ivabradine Versus Up-titrated Bisoprolol for Persistent Tachycardia After Primary PCI in Anterior STEMI: A Single-center, Open-label, Pragmatic RCT23
Transcatheter Tricuspid Valve Replacement Versus Totally Thoracoscopic Beating-Heart Surgery for Tricuspid Regurgitation21
Colchicine Inhibits NETs and Alleviates Cardiac Remodeling after Acute Myocardial Infarction20
DTX1 Regulates Aortic Dissection Progression by Modulating Vascular Smooth Muscle Cell Phenotypic Switching via Ubiquitination of ITGA520
Advances in MicroRNA Therapy for Heart Failure: Clinical Trials, Preclinical Studies, and Controversies19
Insulin Resistance Triggers Atherosclerosis: Caveolin 1 Cooperates with PKCzeta to Block Insulin Signaling in Vascular Endothelial Cells19
Beyond the Broken Heart: Exploring Metabolic Anti-ischemic Solutions for Takotsubo Syndrome19
Minimal Adherence Threshold to Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation to Reduce the Risk of Thromboembolism and Death: A Nationwide Cohort Study18
Shedding Light on Treatment Options for Coronary Vasomotor Disorders: A Systematic Review18
Effect of Intensive Lipid-Lowering Therapy on Coronary Plaque Stabilization Derived from Optical Coherence Tomography: a Meta-analysis and Meta-regression17
Thorough Physiological Assessment in Non-Culprit Vessels of Patients with Acute Myocardial Infarction: Is It a Required Action?16
Are Sodium-Glucose Cotransporter-2 Inhibitors the Cherry on Top of Cardio-Oncology Care?16
Enhancing Glucose Uptake as a Means to Protect the Heart During Cardiopulmonary Bypass or Ischemia–Reperfusion Injury16
Pericardial Administration of Extracellular Vesicles Derived from Bone Marrow Stem Cells Improved Doxorubicin-induced Heart Failure with Mid Range Ejection Fraction (HFmrEF) in Rats16
Early Initiation of SGLT2 Inhibitors in Acute Heart Failure: a Focus on Diuresis and Renal Protection16
Amiodarone for the Management of Acute Atrial Arrhythmias After Lung Transplant15
Interactions Between Direct Oral Anticoagulants and Drugs Involving CYP-Enzymes and P-gp Transporters Detected by a Clinical Decision Support System: A Retrospective Cohort Study15
Potentially Clinically Significant Drug-Drug Interactions in Older Adults with Atrial Fibrillation and Multimorbidity: Prevalence, Correlates, and Association with Adverse Clinical Outcomes in a Swedi15
Comment On: “Association of Intravenous Magnesium Sulfate with Mortality in Patients with Myocardial Infarction: A Retrospective Cohort Study”15
Nicorandil — an Effective Multitarget Drug for Cardioprotection?14
“Big Things Come in Small Packages”: Are Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicles a Useful Therapeutic Tool for Heart Failure?14
Low-Dose Rivaroxaban vs. Aspirin in Addition to Clopidogrel After Percutaneous Coronary Intervention in Coronary Atherosclerotic Heart Disease Patients with Gastrointestinal Disease14
A Multimodal Omics Framework to Empower Target Discovery for Cardiovascular Regeneration14
Antiphospholipid Syndrome: State of the Art of Clinical Management14
The Statin Floor Effect: a Mechanistic Framework for Residual Cardiovascular Risk13
Critical Evaluation of Ivabradine’s Cardioprotective Potential Against Anthracycline-Induced Cardiotoxicity: A Comprehensive Review of Clinical Trials, Preclinical Studies, and Current Treatment Guide13
Baxdrostat and Aldosterone Synthase Inhibitors: A New Class for Treatment-resistant Hypertension13
CTRP5 Attenuates Doxorubicin-Induced Cardiotoxicity Via Inhibiting TLR4/NLRP3 Signaling13
Influence of a Short Course of Ritonavir Used as Booster in Antiviral Therapies Against SARS-CoV-2 on the Exposure of Atorvastatin and Rosuvastatin12
Tanshinone IIA through the PGK1/PDHK1 Pathway Affecting Macrophage Reprogramming in the Repair Process of Myocardial Infarction12
Combining Forces: a New Variation in Antegrade CTO-PCI Technique12
Clinical Efficacy and Safety of Novel Anticoagulants for the Management of Venous Thromboembolism in Patients with Cancer: A Systematic Review and Meta-Analysis12
Mitochondria at the Heart of Ischemia-Reperfusion (I/R) Injury: the HOXB5-Sirt5 Axis12
Inhibition of PCSK9 Improves the Development of Pulmonary Arterial Hypertension Via Down-Regulating Notch3 Expression11
Revealing the Process of Vein Graft Failure: A Panoramic Review from Etiology Analysis to Mechanism Explanation and Treatment Strategy11
Angiography-based Fractional Flow Reserve for the Prediction of Clinical Outcomes After Drug-coated Balloon or Plain Old Balloon Angioplasty11
Correction to: Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts11
Canagliflozin Pretreatment Attenuates Myocardial Dysfunction and Improves Postcardiac Arrest Outcomes After Cardiac Arrest and Cardiopulmonary Resuscitation in Mice11
Comparison Between Drug-Coated Balloon and Stents in Large De Novo Coronary Artery Disease: A Systematic Review and Meta-Analysis of RCT Data11
Beyond Aspirin: Reevaluating Rivaroxaban-Clopidogrel Therapy in PCI Patients with Gastrointestinal Disease11
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding11
Impact of Warfarin and Dual Antiplatelet Therapy on Graft Failure After Coronary Endarterectomy: A Retrospective Cohort Study11
Sacubitril/valsartan improves all-cause mortality in heart failure patients with reduced ejection fraction and chronic kidney disease10
Establishment and Validation of the Nomogram Model and the Probability of Silent Cerebral Infarction After Ablation Atrial Fibrillation10
A Comprehensive Review of the Pleiotropic Effects of Ticagrelor10
Development and Validation of a Novel Prognostic Model Predicting the Atrial Fibrillation Recurrence Risk for Persistent Atrial Fibrillation Patients Treated with Nifekalant During the First Radiofreq10
Sulfated Galactofucan from Sargassum Thunbergii Attenuates Atherosclerosis by Suppressing Inflammation Via the TLR4/MyD88/NF-κB Signaling Pathway10
Antacid Therapy in Coronary Artery Disease and Heart Failure: Proton Pump Inhibitors vs. H2 Receptor Blockers10
Levosimendan for Diastolic Dysfunction?10
Direct Oral Anticoagulants in Patients with Atrial Fibrillation and Significant Mitral Stenosis—a Preliminary Meta-Analysis10
Novel Protective Role for Gut Microbiota-derived Metabolite PAGln in Doxorubicin-induced Cardiotoxicity10
Safety Analysis of Spironolactone Use in Patients Undergoing Percutaneous Coronary Intervention with High Bleeding Risk: A Propensity Score-Matched Study10
Effects of Glucagon-Like Peptide-1 Receptor Agonist (GLP-1RA) on Cardiac Structure and Function: A Systematic Review and Meta-Analysis of Randomized-Controlled Trials10
Reading Tea Leaves: Epigallocatechin-3-Gallate for Targeting Atrial Fibrosis10
Considerations for Left Atrial Appendage Occlusion During Cardiac Surgery10
Epicardial Adipocytes in Cardiac Pathology and Healing9
Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular Disease9
Levosimendan: A New Therapeutical Strategy in Patients with Renal Insufficiency9
Finerenone in Heart Failure with Preserved or Mildly Reduced Ejection Fraction: A Promising Therapeutic Advancement9
Finerenone Versus Spironolactone for Heart Failure with Preserved Ejection Fraction9
Dapagliflozin for Atrial Fibrillation9
Perioperative and Long-Term Cardiorenal Outcomes of SGLT2 Inhibitors in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis9
Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants Compared with Vitamin K Antagonists in Patients with Atrial Fibrillation and Type 2 Valvular Heart Disease: A Systematic Review and 9
Open Issues in the Management of Otcagerian Patients with Atrial Fibrillation and Chronic Kidney Disease: Are we Ready for Left Atrial Appendage Occlusion (LAAO) as First-Line Therapy for Thromboembol9
Factor XIa Inhibitors Versus Direct Oral Anticoagulants for Atrial Fibrillation: A Systematic Review and Meta-analysis of Randomized Controlled Trials9
Vagus Nerve Stimulation by Focused Ultrasound Attenuates Acute Myocardial Ischemia/Reperfusion Injury Predominantly Through Cholinergic Anti-inflammatory Pathway9
Exercise Prevents Glucocorticoid-Induced Myocardial 4-Hydroxynonenal Production9
Vps16 Attenuates Myocardial Ischemia/reperfusion Injury by Interacting with UVRAG and Activating Rab79
Differential Outcomes of Beta-Blockers According to Heart Rate Following Myocardial Infarction with Reduced Left Ventricular Ejection Fraction8
ROS-Activated TRPM2 Channel: Calcium Homeostasis in Cardiovascular/renal System and Speculation in Cardiorenal Syndrome8
Safety and Effectiveness of Antidysrhythmic Drugs for Pharmacologic Cardioversion of Recent-Onset Atrial Fibrillation: a Systematic Review and Bayesian Network Meta-analysis8
Interpreting Mitochondrial Bioenergetics in Ischaemia–Reperfusion Injury: Caution on Causality and Methodological Consistency8
Liraglutide Protects Against Diastolic Dysfunction and Improves Ventricular Protein Translation8
Sacubitril/Valsartan in Dialysis Patients: Update on Current Perspectives8
Enhanced Reendothelialization and Thrombosis Prevention with a New Drug-Eluting Stent8
Combined Catheter Ablation and Left Atrial Appendage Occlusion in Atrial Fibrillation: From Data to Clinical Reality8
Direct Oral Anticoagulants: Navigating Through Clinical Challenges8
Monocyte Activation Drives Atrial Fibrillation in Hypertension8
Evaluation of the Efficacy of Sacubitril/Valsartan on Radiofrequency Ablation in Patients with Hypertension and Persistent Atrial Fibrillation8
Comparison of His–Purkinje Conduction System Pacing with Atrial–Ventricular Node Ablation and Pharmacotherapy in HFpEF Patients with Recurrent Persistent Atrial Fibrillation (HPP-AF study)8
GDF11 Regulates Vascular Smooth Muscle Cell Phenotype Switching to Prevent Aortic Aneurysm Formation8
PCSK9 and Lipid Metabolism: Genetic Variants, Current Therapies, and Cardiovascular Outcomes8
Bioresorbable Vascular Scaffolds: a Dissolving Dream?7
GLP-1 Receptor Agonists and Cardiac Health: Insights from a Systematic Review7
Lipoprotein (a) and Coronary Atherosclerosis in Intracoronary Imaging - YELLOW II – Lp(a) Study7
Clinical Outcomes of Early Rhythm or Rate Control for New Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement7
Metabolic Syndrome and Breast Cancer Risk: an Age-Dependent Paradox?7
Emodin Suppresses NLRP3/GSDMD-induced Inflammation via the TLR4/MyD88/NF-κB Signaling Pathway in Atherosclerosis7
When Less is More: Drug-Coated Balloons Threaten a Paradigm Revolution7
Comparison of Efficacy and Safety Between Drug-Coated Balloons Versus Drug-Eluting Stents in the Treatment of De Novo Coronary Lesions in Large Vessels: A Study-Level Meta-Analysis of Randomized Contr7
Reassessing Ivabradine: Potential Benefits and Risks in Atrial Fibrillation Therapy7
Effect of Prolonged Use of Dronedarone on Recurrence in Patients with Non-Paroxysmal Atrial Fibrillation After Radiofrequency Ablation (DORIS): Rationale and Design of a Randomized Multicenter, Double7
Ticagrelor versus Clopidogrel After Left Main Coronary Artery Disease Intervention7
Critically Evaluating TriClip Edge-to-Edge Repair for Severe Tricuspid Regurgitation with Large Coaptation Gaps: Limitations of a Nine-Patient Retrospective Study and Evidence-Based Recommendations fo7
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data7
Precision Secondary Prevention after Myocardial Infarction: Who Still Benefits from β-Blockade?7
Clinical Efficacy and Safety of Early Intravenous Administration of Beta-Blockers in Patients Suffering from Acute ST-Segment Elevation Myocardial Infarction Without Heart Failure Undergoing Primary P7
US Population Eligibility and Estimated Impact of Semaglutide Treatment on Obesity Prevalence and Cardiovascular Disease Events7
Hyperglycemia-Induced Overexpression of PH Domain Leucine-Rich Repeat Protein Phosphatase 1 (PHLPP1) Compromises the Cardioprotective Effect of Ischemic Postconditioning Via Modulation of the Akt/Mst17
Sitagliptin Ameliorates Creb5/lncRNA ENSMUST00000213271-Mediated Vascular Endothelial Dysfunction in Obese Mice6
Ticagrelor versus Clopidogrel: Two Controversial Drugs in Patients with Acute Coronary Syndrome6
Exosomes from Stem Cells: A Future Alternative to Whole-Cell Therapy in Heart Failure6
Correction to: The Impact of CYP2C19 Genotype on the Platelet Reactivity Index (PRI) among Chronic Coronary Syndromes (CCS) Patients Undergoing Percutaneous Coronary Intervention (PCI): Affectability 6
The Influence of the FFAR4 Agonist TUG-891 on Liver Steatosis in ApoE-Knockout Mice6
Associations of SGLT2i with Cardiorenal Outcomes Among Diabetics with Prostate Cancer on Hormone Therapy6
Screening of Anti-atherosclerosis Drugs Based on the Apolipoprotein apoeb Gene Knockout Zebrafish Model6
Functional and Metabolic Imaging in Heart Failure with Preserved Ejection Fraction: Promises, Challenges, and Clinical Utility6
The Role of the Pentose Phosphate Pathway in Cardiovascular Diseases6
Uncertainty Regarding the Safety of SGLT-2 Inhibitors Prior to PCI: the Impact of Unmeasured Confounding and Statistical Power6
US Population Eligibility and Estimated Impact of Tirzepatide Treatment on Obesity Prevalence and Cardiovascular Disease Events6
Hydrogen Sulfide Ameliorates Heart Aging by Downregulating Matrix Metalloproteinase-96
Lipoprotein(a) in Cardiovascular Diseases and Emerging Therapeutic Strategies6
Can It Be that Metabolic Syndrome Protect against Breast Cancer6
The Effect of Colchicine in Acute Myocardial Infarction5
The Combined Empagliflozin and Sacubitril/Valsartan Therapy Attenuates Isoproterenol-Induced Heart Failure in Rats: Functional, Molecular, and Structural Insights5
Limitations in PAR1-Targeted Screening of Antithrombotic Phytochemicals5
Downregulated TRIM35 Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress and Inflammation via Inhibiting TLR4/NF-κB Pathway5
Pulmonary Circulation Under Pressure: Pathophysiological and Therapeutic Implications of BK Channel5
From Peripheral Immune Signatures to Cardiac Remodeling: Interpreting the Monocyte Axis in Hypertension-Related Atrial Fibrillation5
Predictors of Plasma Levels of Direct Oral Anticoagulants Among Patients with Atrial Fibrillation in Need of Elective Cardiac Procedures5
Doxorubicin-Induced Cardiotoxicity: Can Andrographolide Provide a Silver Lining?5
Empagliflozin Supplementation in Cardioplegic Solution Improves Donor Heart Preservation by Maintaining Mitochondrial Homeostasis5
Optimizing Lipid-Lowering Strategies Beyond Current Evidence5
Discharge of Acute Coronary Syndrome Patients on Sub-Optimal Dual Anti-Platelet Therapy: A Single Center Experience5
Concerns Regarding Midodrine Utilization in Cancer Patients with Heart Failure5
The Clinical Efficacy and Safety of Bempedoic Acid in Patients at Elevated Risk of Cardiovascular Disease: A Meta-Analysis of Randomized Clinical Trials5
Comparing the Clinical Outcomes Observed with Rivaroxaban Versus Warfarin for the Management of Obese Patients with Non-valvular Atrial Fibrillation: a Systematic Review and Meta-analysis5
Beyond Hepatoprotection—The Cardioprotective Effects of Bicyclol in Diabetes5
When Is It Appropriate to Publish a Meta-Analysis in Cardiovascular Drugs and Therapy?5
Refining Antithrombotic Therapy in Coronary Artery Ectasia: A Call for Phenotype-Driven Trials and Precision Dosing5
Dapagliflozin Inhibits Thrombin Induced ADAM17 Phosphorylation and Downstream ERK/p-c-Jun-mediated CTGF Induction to Prevent Neointimal Hyperplasia5
Effect of Beta-Blocker on Long-Term Major Cardiovascular Events in High Atherosclerotic Risk Population5
Doxorubicin-Induced Cardiac Remodeling: Mechanisms and Mitigation Strategies5
Numbers Needed to Treat for Preventing Adverse Cardiovascular Outcomes for Sodium-Glucose Cotransporter 2 Inhibitors vs. Dipeptidyl Peptidase 4 Inhibitors: The Hong Kong Diabetes Study5
Comment on: “Effect of Bisoprolol Versus Other Beta-Blockers on Glycemic Control and Metabolic Parameters in Type 2 Diabetes: A Retrospective Cohort Study”5
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