Cardiovascular Drugs and Therapy

Papers
(The TQCC of Cardiovascular Drugs and Therapy is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Vaccine Targeting Alpha 1D-Adrenergic Receptor Improved Metabolic Syndrome in Mice49
MicroRNA-205-5p: A Potential Therapeutic Target for Combating Unstable Atherogenesis?40
Correction to: Hemodynamic Response to Oral Vasodilator Therapy in Systemic Sclerosis‑Related Pulmonary Hypertension38
Immediate Versus Staged Complete Revascularization in Patients Presenting with Acute Coronary Syndrome and Multivessel Coronary Disease Without Cardiac Shock: A Study-Level Meta-analysis of Randomized37
Beyond the Broken Heart: Exploring Metabolic Anti-ischemic Solutions for Takotsubo Syndrome33
Advances in MicroRNA Therapy for Heart Failure: Clinical Trials, Preclinical Studies, and Controversies30
The Infarct-Limiting Effect of Remote Ischemic Conditioning in Rats Is Not Affected by Aspirin28
Ivabradine Versus Up-titrated Bisoprolol for Persistent Tachycardia After Primary PCI in Anterior STEMI: A Single-center, Open-label, Pragmatic RCT26
Association Between the Magnitude of Glycemic Control and Body Weight Loss With GLP-1 Receptor Agonists and Risk of Atherosclerotic Cardiovascular Disease: A Systematic Review and Meta-analyses of Ran25
DTX1 Regulates Aortic Dissection Progression by Modulating Vascular Smooth Muscle Cell Phenotypic Switching via Ubiquitination of ITGA524
Transcatheter Tricuspid Valve Replacement Versus Totally Thoracoscopic Beating-Heart Surgery for Tricuspid Regurgitation24
Insulin Resistance Triggers Atherosclerosis: Caveolin 1 Cooperates with PKCzeta to Block Insulin Signaling in Vascular Endothelial Cells23
Opioid-Sparing Effects of Erector Spinae Plane Block in Off-Pump Coronary Artery Bypass Grafting with Median Sternotomy: A Randomized Controlled Trial23
Methodological Considerations in Evaluating Plaque Stabilization in Patients with High Lipoprotein(a)23
Association of Angiotensin Receptor-Neprilysin Inhibitors Use and Better Cardiorenal Outcomes in Patients With Heart Failure and Acute Kidney Disease21
RELM-β Augmented Hypoxia-Induced Pulmonary Hypertension Through Interacting with GIPC1, OR1N1 and CLIC420
Early in-hospital use of SGLT2i in heart failure patients with ischemic etiology19
Targeting SIRT3 in Diabetic Cardiomyopathy: Mechanism-Based Therapeutic Strategies19
Impact of CYP2C19 Genotype on Efficacy and Safety of Clopidogrel-based Antiplatelet Therapy in Stroke or Transient Ischemic Attack Patients: An Updated Systematic Review and Meta-analysis of Non-East 19
Effect of Intensive Lipid-Lowering Therapy on Coronary Plaque Stabilization Derived from Optical Coherence Tomography: a Meta-analysis and Meta-regression18
Efficacy and Safety of Inclisiran in Patients with Polyvascular Disease: Pooled, Post Hoc Analysis of the ORION-9, ORION-10, and ORION-11 Phase 3 Randomized Controlled Trials18
Are Sodium-Glucose Cotransporter-2 Inhibitors the Cherry on Top of Cardio-Oncology Care?18
Enhancing Glucose Uptake as a Means to Protect the Heart During Cardiopulmonary Bypass or Ischemia–Reperfusion Injury17
Minimal Adherence Threshold to Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation to Reduce the Risk of Thromboembolism and Death: A Nationwide Cohort Study17
Methodological Considerations Regarding “Impact of Nitric Oxide Metabolites on Early Perioperative Biochemical Changes and Postoperative Complications in High-BMI Patients Undergoing On-Pump CABG”16
Low-Dose Rivaroxaban vs. Aspirin in Addition to Clopidogrel After Percutaneous Coronary Intervention in Coronary Atherosclerotic Heart Disease Patients with Gastrointestinal Disease16
Antiphospholipid Syndrome: State of the Art of Clinical Management16
Interactions Between Direct Oral Anticoagulants and Drugs Involving CYP-Enzymes and P-gp Transporters Detected by a Clinical Decision Support System: A Retrospective Cohort Study16
Potentially Clinically Significant Drug-Drug Interactions in Older Adults with Atrial Fibrillation and Multimorbidity: Prevalence, Correlates, and Association with Adverse Clinical Outcomes in a Swedi16
The Apelin-APJ Axis in Heart Failure: Mechanistic Insights, Clinical Evidence, and Translational Challenges16
Pericardial Administration of Extracellular Vesicles Derived from Bone Marrow Stem Cells Improved Doxorubicin-induced Heart Failure with Mid Range Ejection Fraction (HFmrEF) in Rats15
Comment On: “Association of Intravenous Magnesium Sulfate with Mortality in Patients with Myocardial Infarction: A Retrospective Cohort Study”15
Thorough Physiological Assessment in Non-Culprit Vessels of Patients with Acute Myocardial Infarction: Is It a Required Action?15
Amiodarone for the Management of Acute Atrial Arrhythmias After Lung Transplant15
Effects of Age, BMI and Creatinine Clearance on Edoxaban Plasma Concentrations in Non-Valvular Atrial Fibrillation Patients14
Early Initiation of SGLT2 Inhibitors in Acute Heart Failure: a Focus on Diuresis and Renal Protection14
Mitochondria at the Heart of Ischemia-Reperfusion (I/R) Injury: the HOXB5-Sirt5 Axis13
Nicorandil — an Effective Multitarget Drug for Cardioprotection?13
Baxdrostat and Aldosterone Synthase Inhibitors: A New Class for Treatment-resistant Hypertension13
A Multimodal Omics Framework to Empower Target Discovery for Cardiovascular Regeneration13
CTRP5 Attenuates Doxorubicin-Induced Cardiotoxicity Via Inhibiting TLR4/NLRP3 Signaling13
“Big Things Come in Small Packages”: Are Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicles a Useful Therapeutic Tool for Heart Failure?12
The Statin Floor Effect: a Mechanistic Framework for Residual Cardiovascular Risk12
Correction to: Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts12
Critical Evaluation of Ivabradine’s Cardioprotective Potential Against Anthracycline-Induced Cardiotoxicity: A Comprehensive Review of Clinical Trials, Preclinical Studies, and Current Treatment Guide12
Combining Forces: a New Variation in Antegrade CTO-PCI Technique12
Influence of a Short Course of Ritonavir Used as Booster in Antiviral Therapies Against SARS-CoV-2 on the Exposure of Atorvastatin and Rosuvastatin12
Impact of Nitric Oxide Metabolites On Early Perioperative Biochemical Changes and Postoperative Complications in High-BMI Patients Undergoing On-Pump CABG: an Exploratory Observational Cohort Study12
Clinical Efficacy and Safety of Novel Anticoagulants for the Management of Venous Thromboembolism in Patients with Cancer: A Systematic Review and Meta-Analysis12
Tanshinone IIA through the PGK1/PDHK1 Pathway Affecting Macrophage Reprogramming in the Repair Process of Myocardial Infarction12
Comparison Between Drug-Coated Balloon and Stents in Large De Novo Coronary Artery Disease: A Systematic Review and Meta-Analysis of RCT Data11
Beyond Aspirin: Reevaluating Rivaroxaban-Clopidogrel Therapy in PCI Patients with Gastrointestinal Disease11
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding11
Impact of Warfarin and Dual Antiplatelet Therapy on Graft Failure After Coronary Endarterectomy: A Retrospective Cohort Study11
Guideline-directed Low-density Lipoprotein Cholesterol Management After Acute Coronary Syndrome in Patients With Mental Illness: a Population-based Study11
Canagliflozin Pretreatment Attenuates Myocardial Dysfunction and Improves Postcardiac Arrest Outcomes After Cardiac Arrest and Cardiopulmonary Resuscitation in Mice11
Angiography-based Fractional Flow Reserve for the Prediction of Clinical Outcomes After Drug-coated Balloon or Plain Old Balloon Angioplasty11
Considerations for Left Atrial Appendage Occlusion During Cardiac Surgery11
A Comprehensive Review of the Pleiotropic Effects of Ticagrelor11
Levosimendan for Diastolic Dysfunction?11
Revealing the Process of Vein Graft Failure: A Panoramic Review from Etiology Analysis to Mechanism Explanation and Treatment Strategy11
Inhibition of PCSK9 Improves the Development of Pulmonary Arterial Hypertension Via Down-Regulating Notch3 Expression11
Establishment and Validation of the Nomogram Model and the Probability of Silent Cerebral Infarction After Ablation Atrial Fibrillation10
Sulfated Galactofucan from Sargassum Thunbergii Attenuates Atherosclerosis by Suppressing Inflammation Via the TLR4/MyD88/NF-κB Signaling Pathway10
Novel Protective Role for Gut Microbiota-derived Metabolite PAGln in Doxorubicin-induced Cardiotoxicity10
Safety Analysis of Spironolactone Use in Patients Undergoing Percutaneous Coronary Intervention with High Bleeding Risk: A Propensity Score-Matched Study10
Perioperative and Long-Term Cardiorenal Outcomes of SGLT2 Inhibitors in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis10
Reading Tea Leaves: Epigallocatechin-3-Gallate for Targeting Atrial Fibrosis10
Vagus Nerve Stimulation by Focused Ultrasound Attenuates Acute Myocardial Ischemia/Reperfusion Injury Predominantly Through Cholinergic Anti-inflammatory Pathway10
Complement Component C4B Prioritization Through Drug‒Target Mendelian Randomization and Proteomic Analysis Reveals a Novel Therapeutic Target for Calcific Aortic Valve Stenosis9
Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular Disease9
GDF11 Regulates Vascular Smooth Muscle Cell Phenotype Switching to Prevent Aortic Aneurysm Formation9
Vps16 Attenuates Myocardial Ischemia/reperfusion Injury by Interacting with UVRAG and Activating Rab79
Open Issues in the Management of Otcagerian Patients with Atrial Fibrillation and Chronic Kidney Disease: Are we Ready for Left Atrial Appendage Occlusion (LAAO) as First-Line Therapy for Thromboembol9
Direct Oral Anticoagulants in Patients with Atrial Fibrillation and Significant Mitral Stenosis—a Preliminary Meta-Analysis9
Dapagliflozin for Atrial Fibrillation9
Factor XIa Inhibitors Versus Direct Oral Anticoagulants for Atrial Fibrillation: A Systematic Review and Meta-analysis of Randomized Controlled Trials9
Exercise Prevents Glucocorticoid-Induced Myocardial 4-Hydroxynonenal Production9
Direct Oral Anticoagulants: Navigating Through Clinical Challenges9
Sacubitril/valsartan improves all-cause mortality in heart failure patients with reduced ejection fraction and chronic kidney disease9
Finerenone Versus Spironolactone for Heart Failure with Preserved Ejection Fraction9
Epicardial Adipocytes in Cardiac Pathology and Healing9
Levosimendan: A New Therapeutical Strategy in Patients with Renal Insufficiency9
Sacubitril/Valsartan in Dialysis Patients: Update on Current Perspectives9
Safety and Effectiveness of Antidysrhythmic Drugs for Pharmacologic Cardioversion of Recent-Onset Atrial Fibrillation: a Systematic Review and Bayesian Network Meta-analysis8
Enhanced Reendothelialization and Thrombosis Prevention with a New Drug-Eluting Stent8
Anatomophysiopathology of Vein Graft Arterialization: The Potential Damage of Venous Valves8
Methodological Considerations Regarding Electrophysiological Assessment and Outcome Interpretation in AF-HFpEF Treated with Dapagliflozin Plus Sacubitril/Valsartan8
Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants Compared with Vitamin K Antagonists in Patients with Atrial Fibrillation and Type 2 Valvular Heart Disease: A Systematic Review and 8
Differential Outcomes of Beta-Blockers According to Heart Rate Following Myocardial Infarction with Reduced Left Ventricular Ejection Fraction8
Finerenone in Heart Failure with Preserved or Mildly Reduced Ejection Fraction: A Promising Therapeutic Advancement8
Evaluation of the Efficacy of Sacubitril/Valsartan on Radiofrequency Ablation in Patients with Hypertension and Persistent Atrial Fibrillation8
Monocyte Activation Drives Atrial Fibrillation in Hypertension8
Liraglutide Protects Against Diastolic Dysfunction and Improves Ventricular Protein Translation8
PCSK9 and Lipid Metabolism: Genetic Variants, Current Therapies, and Cardiovascular Outcomes8
Interpreting Mitochondrial Bioenergetics in Ischaemia–Reperfusion Injury: Caution on Causality and Methodological Consistency8
Combined Catheter Ablation and Left Atrial Appendage Occlusion in Atrial Fibrillation: From Data to Clinical Reality7
Clinical Outcomes of Early Rhythm or Rate Control for New Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement7
Critically Evaluating TriClip Edge-to-Edge Repair for Severe Tricuspid Regurgitation with Large Coaptation Gaps: Limitations of a Nine-Patient Retrospective Study and Evidence-Based Recommendations fo7
Reassessing Ivabradine: Potential Benefits and Risks in Atrial Fibrillation Therapy7
Comparison of His–Purkinje Conduction System Pacing with Atrial–Ventricular Node Ablation and Pharmacotherapy in HFpEF Patients with Recurrent Persistent Atrial Fibrillation (HPP-AF study)7
Ticagrelor versus Clopidogrel After Left Main Coronary Artery Disease Intervention7
Bioresorbable Vascular Scaffolds: a Dissolving Dream?7
ROS-Activated TRPM2 Channel: Calcium Homeostasis in Cardiovascular/renal System and Speculation in Cardiorenal Syndrome7
Metabolic Syndrome and Breast Cancer Risk: an Age-Dependent Paradox?7
Effect of Prolonged Use of Dronedarone on Recurrence in Patients with Non-Paroxysmal Atrial Fibrillation After Radiofrequency Ablation (DORIS): Rationale and Design of a Randomized Multicenter, Double7
Ticagrelor versus Clopidogrel: Two Controversial Drugs in Patients with Acute Coronary Syndrome6
Lipoprotein (a) and Coronary Atherosclerosis in Intracoronary Imaging - YELLOW II – Lp(a) Study6
When Less is More: Drug-Coated Balloons Threaten a Paradigm Revolution6
Comparison of Efficacy and Safety Between Drug-Coated Balloons Versus Drug-Eluting Stents in the Treatment of De Novo Coronary Lesions in Large Vessels: A Study-Level Meta-Analysis of Randomized Contr6
The Influence of the FFAR4 Agonist TUG-891 on Liver Steatosis in ApoE-Knockout Mice6
US Population Eligibility and Estimated Impact of Tirzepatide Treatment on Obesity Prevalence and Cardiovascular Disease Events6
Clinical Efficacy and Safety of Early Intravenous Administration of Beta-Blockers in Patients Suffering from Acute ST-Segment Elevation Myocardial Infarction Without Heart Failure Undergoing Primary P6
Precision Secondary Prevention after Myocardial Infarction: Who Still Benefits from β-Blockade?6
GLP-1 Receptor Agonists and Cardiac Health: Insights from a Systematic Review6
Uncertainty Regarding the Safety of SGLT-2 Inhibitors Prior to PCI: the Impact of Unmeasured Confounding and Statistical Power6
Can It Be that Metabolic Syndrome Protect against Breast Cancer6
Emodin Suppresses NLRP3/GSDMD-induced Inflammation via the TLR4/MyD88/NF-κB Signaling Pathway in Atherosclerosis6
US Population Eligibility and Estimated Impact of Semaglutide Treatment on Obesity Prevalence and Cardiovascular Disease Events6
Lipoprotein(a) in Cardiovascular Diseases and Emerging Therapeutic Strategies6
From Peripheral Immune Signatures to Cardiac Remodeling: Interpreting the Monocyte Axis in Hypertension-Related Atrial Fibrillation6
Correction to: The Impact of CYP2C19 Genotype on the Platelet Reactivity Index (PRI) among Chronic Coronary Syndromes (CCS) Patients Undergoing Percutaneous Coronary Intervention (PCI): Affectability 6
Downregulated TRIM35 Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress and Inflammation via Inhibiting TLR4/NF-κB Pathway5
Effect of Beta-Blocker on Long-Term Major Cardiovascular Events in High Atherosclerotic Risk Population5
Doxorubicin-Induced Cardiac Remodeling: Mechanisms and Mitigation Strategies5
The Role of the Pentose Phosphate Pathway in Cardiovascular Diseases5
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data5
Re: Effects of Dapagliflozin Combined with Sacubitril/Valsartan on Cardiac Electrophysiology and Quantitative Myocardial Motion Parameters in Patients with Atrial Fibrillation and Heart Failure with P5
Refining Antithrombotic Therapy in Coronary Artery Ectasia: A Call for Phenotype-Driven Trials and Precision Dosing5
When Is It Appropriate to Publish a Meta-Analysis in Cardiovascular Drugs and Therapy?5
The Clinical Efficacy and Safety of Bempedoic Acid in Patients at Elevated Risk of Cardiovascular Disease: A Meta-Analysis of Randomized Clinical Trials5
Empagliflozin Supplementation in Cardioplegic Solution Improves Donor Heart Preservation by Maintaining Mitochondrial Homeostasis5
Optimizing Lipid-Lowering Strategies Beyond Current Evidence5
Screening of Anti-atherosclerosis Drugs Based on the Apolipoprotein apoeb Gene Knockout Zebrafish Model5
Exosomes from Stem Cells: A Future Alternative to Whole-Cell Therapy in Heart Failure5
Sitagliptin Ameliorates Creb5/lncRNA ENSMUST00000213271-Mediated Vascular Endothelial Dysfunction in Obese Mice5
Hydrogen Sulfide Ameliorates Heart Aging by Downregulating Matrix Metalloproteinase-95
Doxorubicin-Induced Cardiotoxicity: Can Andrographolide Provide a Silver Lining?5
Comment on: “Effect of Bisoprolol Versus Other Beta-Blockers on Glycemic Control and Metabolic Parameters in Type 2 Diabetes: A Retrospective Cohort Study”5
The Effect of Colchicine in Acute Myocardial Infarction5
Beyond Hepatoprotection—The Cardioprotective Effects of Bicyclol in Diabetes5
Limitations in PAR1-Targeted Screening of Antithrombotic Phytochemicals5
Concerns Regarding Midodrine Utilization in Cancer Patients with Heart Failure5
Discharge of Acute Coronary Syndrome Patients on Sub-Optimal Dual Anti-Platelet Therapy: A Single Center Experience5
Cellular Senescence in Diabetic Cardiomyopathy: Mechanistic Insights and Therapeutic Perspectives5
Pulmonary Circulation Under Pressure: Pathophysiological and Therapeutic Implications of BK Channel5
Associations of SGLT2i with Cardiorenal Outcomes Among Diabetics with Prostate Cancer on Hormone Therapy5
Predictors of Plasma Levels of Direct Oral Anticoagulants Among Patients with Atrial Fibrillation in Need of Elective Cardiac Procedures5
Numbers Needed to Treat for Preventing Adverse Cardiovascular Outcomes for Sodium-Glucose Cotransporter 2 Inhibitors vs. Dipeptidyl Peptidase 4 Inhibitors: The Hong Kong Diabetes Study5
Therapeutic Ultrasound in Cardiovascular Medicine: Applications of Low-intensity Pulsed Ultrasound and Ultrasound-targeted Microbubble Destruction5
The Combined Empagliflozin and Sacubitril/Valsartan Therapy Attenuates Isoproterenol-Induced Heart Failure in Rats: Functional, Molecular, and Structural Insights5
Dapagliflozin Inhibits Thrombin Induced ADAM17 Phosphorylation and Downstream ERK/p-c-Jun-mediated CTGF Induction to Prevent Neointimal Hyperplasia5
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