Epilepsy Research

Article	Citations
Ketogenic diet and Neuroinflammation	92
Network of depression and anxiety symptoms in patients with epilepsy	40
A phase 1b/2a study of soticlestat as adjunctive therapy in participants with developmental and/or epileptic encephalopathies	33
Ketogenic diet, neuroprotection, and antiepileptogenesis	33
A comparison of the gut microbiota among adult patients with drug-responsive and drug-resistant epilepsy: An exploratory study	31
A prospective multicenter study of laser ablation for drug resistant epilepsy – One year outcomes	30
Exploring quality of life in individuals with a severe developmental and epileptic encephalopathy, CDKL5 Deficiency Disorder	29
Serotonin 5-HT4 receptors play a critical role in the action of fenfluramine to block seizure-induced sudden death in a mouse model of SUDEP	26
Cannabidiolic acid exhibits entourage-like improvements of anticonvulsant activity in an acute rat model of seizures	25
Patterns of seizure spread in temporal lobe epilepsy are associated with distinct white matter tracts	25
Computational characteristics of interictal EEG as objective markers of epileptic spasms	24
Inhibitory effect of anti-seizure medications on ionotropic glutamate receptors: special focus on AMPA receptor subunits	22
Dravet syndrome: Advances in etiology, clinical presentation, and treatment	22
A reliable interictal EEG grading scale for children with infantile spasms – The 2021 BASED score	22
Clinical pharmacokinetic and pharmacodynamic profile of midazolam nasal spray	21
Management of COVID-19 in patients with seizures: Mechanisms of action of potential COVID-19 drug treatments and consideration for potential drug-drug interactions with anti-seizure medications	20
Efficacy of low glycemic index diet therapy (LGIT) in children aged 2–8 years with drug-resistant epilepsy: A randomized controlled trial	20
The role of inflammatory mediators in epilepsy: Focus on developmental and epileptic encephalopathies and therapeutic implications	20
Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome	19
SP1 activated-lncRNA SNHG1 mediates the development of epilepsy via miR-154-5p/TLR5 axis	19
A unifying mechanism of ketogenic diet action: The multiple roles of nicotinamide adenine dinucleotide	19
Validating the accuracy of administrative healthcare data identifying epilepsy in deceased adults: A Scottish data linkage study	19
CSF high-mobility group box 1 is associated with drug-resistance and symptomatic etiology in adult patients with epilepsy	18
Prolactin levels as a criterion to differentiate between psychogenic non-epileptic seizures and epileptic seizures: A systematic review	18
Persistent racial and ethnic disparities as a potential source of epilepsy surgery underutilization: Analysis of large national datasets from 2006–2016	17

Dravet syndrome in children—A population-based study	17
A systematic review of seizure clusters: Prevalence, risk factors, burden of disease and treatment patterns	17
The impact of Scn1a deficiency and ketogenic diet on the intestinal microbiome: A study in a genetic Dravet mouse model	17
Deciphering the premature mortality in PIGA-CDG – An untold story	17
Acute symptomatic seizures and COVID-19: Hospital-based study	16
Efficacy of adjunctive cenobamate based on number of concomitant antiseizure medications, seizure frequency, and epilepsy duration at baseline: A post-hoc analysis of a randomized clinical study	16
Graph theory application with functional connectivity to distinguish left from right temporal lobe epilepsy	16
Gut microbiota modulation by both Lactobacillus fermentum MSK 408 and ketogenic diet in a murine model of pentylenetetrazole-induced acute seizure	16
Testing broad-spectrum and isoform-preferring HCN channel blockers for anticonvulsant properties in mice	15
Long-term safety and effectiveness of stiripentol in patients with Dravet syndrome: Interim report of a post-marketing surveillance study in Japan	15
Generator replacement with cardiac-based VNS device in children with drug-resistant epilepsy: An observational study	15
An integrative method to quantitatively detect nocturnal motor seizures	15
Long-term effectiveness and adverse effects of ketogenic diet therapy in infants with drug-resistant epilepsy treated at a single center in Argentina	15
Ciprofloxacin for treatment of drug-resistant epilepsy	15
Cytokine-chemokine profiles in the hippocampus of patients with mesial temporal lobe epilepsy and hippocampal sclerosis	15
Pattern analysis of glucose metabolic brain data for lateralization of MRI-negative temporal lobe epilepsy	15
Management of West syndrome during COVID-19 pandemic: A viewpoint from South Asian West Syndrome Research Group	15
Interleukin-33 and oxidative stress in epilepsy patients	14
Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective	14
An evaluation of the diagnostic equivalence of 18F-FDG-PET between hybrid PET/MRI and PET/CT in drug-resistant epilepsy: A pilot study	14
Spike-Wave Index Assessment and Electro-Clinical Correlation in Patients with Encephalopathy Associated with Epileptic State During Slow Sleep (ESES / CSWS); Single-Center Experience	14
Spatiotemporal distribution and age of seizure onset in a pediatric epilepsy surgery cohort with cortical dysplasia	14
Neuroprotective effect of both synbiotics and ketogenic diet in a pentylenetetrazol-induced acute seizure murine model	14
Control of drop attacks with selective posterior callosotomy: Anatomical and prognostic data	14
Anticonvulsant mechanisms of the ketogenic diet and caloric restriction	14
Anti-seizure effects of walnut peptides in mouse models of induced seizure: The involvement of GABA and nitric oxide pathways	13
Dravet syndrome: A quick transition guide for the adult neurologist	13
Prescription patterns of antiepileptic drugs for adult patients with newly diagnosed focal epilepsy from 2006 to 2017 in Japan	13
18F-FDG PET/MR in focal epilepsy: A new step for improving the detection of epileptogenic lesions	13
Surgical candidates in children with epileptic spasms can be selected without invasive monitoring: A report of 70 cases	13
Automated detection and segmentation of focal cortical dysplasias (FCDs) with artificial intelligence: Presentation of a novel convolutional neural network and its prospective clinical validation	13
Changes of HMGB-1 and sTLR4 levels in cerebrospinal fluid of patients with febrile seizures	13
Genomics in the presurgical epilepsy evaluation	12
Neurocognitive Profiles of Pediatric Patients with ESES, Generalized Epilepsy, or Focal Epilepsy	12
Safety and efficacy of adjunctive lacosamide in Chinese and Japanese adults with epilepsy and focal seizures: A long-term, open-label extension of a randomized, controlled trial	12
Relationship between hippocampal subfields and Verbal and Visual memory function in Mesial Temporal Lobe Epilepsy patients	12
Safety, tolerability, and efficacy of brivaracetam as adjunctive therapy in patients with focal seizures, generalized onset seizures, or Unverricht–Lundborg disease: An open-label, long-term follow-up	12
Inhibition of MEK-ERK signaling reduces seizures in two mouse models of tuberous sclerosis complex	12
Long-term results of vagus nerve stimulation in children with Dravet syndrome: Time-dependent, delayed antiepileptic effect	12
Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children	12
Epilepsy duration as an independent predictor of response to vagus nerve stimulation	12
Knowledge atlas of post-traumatic epilepsy research: Based on citespace visualization analysis	12
Development and validation of a clinical score to predict late seizures after intracerebral hemorrhage in Chinese	12
Trends of anti-seizure medication use in pediatric patients in six cities in China from 2013 to 2018	12
Prevalence study of epilepsy in Malaysia	11
Absence epilepsy in male and female WAG/Rij rats: A longitudinal EEG analysis of seizure expression	11
Functional connectivity disturbances of ascending reticular activating system and posterior thalamus in juvenile myoclonic epilepsy in relation with photosensitivity: A resting-state fMRI study	11
Quality of life and stigma in Lebanese people with epilepsy taking medication	11
Challenges in epilepsy diagnosis and management in a low-resource setting: An experience from Bhutan	11
Complementary and alternative medicine (CAM) for epilepsy treatment in the Middle East and North Africa (MENA) region	11

Effect of UGT1A4, UGT2B7, UGT2B15, UGT2B17 and ABC1B polymorphisms on lamotrigine metabolism in Danish patients	11
Voxel-based morphometric MRI post-processing and PET/MRI co-registration reveal subtle abnormalities in cingulate epilepsy	11
Effect of lifetime antiepileptic drug treatment history on efficacy and tolerability of adjunctive brivaracetam in adults with focal seizures: Post-hoc analysis of a randomized, placebo-controlled tri	11
Quality of life and functional limitations in persons with epilepsy	11
Perampanel effectiveness and safety as early add-on treatment for focal-onset seizures: PEREAGAL study	11
Automated video analysis of emotion and dystonia in epileptic seizures	11
Increased mortality after post-stroke epilepsy following primary intracerebral hemorrhage	11
Brain responsive neurostimulation device safety and effectiveness in patients with drug-resistant autoimmune-associated epilepsy	11
Epilepsy stigma in the Republic of Guinea and its socioeconomic and clinical associations: A cross-sectional analysis	11
Efficacy of perampanel in epilepsy patients with autism spectrum disorder	10
The effects of antiepileptic drugs on bone health: A systematic review	10
Brain-derived neurotrophic factor in patients with epilepsy: A systematic review and meta-analysis	10
Phase 2, placebo-controlled clinical study of oral ganaxolone in PCDH19-clustering epilepsy	10
Kinetics of serum brain-derived neurotrophic factor (BDNF) concentration levels in epileptic patients after generalized tonic-clonic seizures	10
A SCN8A variant associated with severe early onset epilepsy and developmental delay: Loss- or gain-of-function?	10
The anterior and centromedian thalamus: Anatomy, function, and dysfunction in epilepsy	10
Cardiac effects of rapid intravenous loading of lacosamide in patients with epilepsy	10
Virtual epilepsy clinics – A Canadian Comprehensive Epilepsy Center experience pre-COVID and during the COVID-19 pandemic period	10
The relation of major depression, OCD, personality disorders and affective temperaments with Temporal lobe epilepsy	10
Is vagal-nerve stimulation safe during pregnancy? A mini review	10
Beyond the Wada: An updated approach to pre-surgical language and memory testing	10
Changes in the use of antiseizure medications in children and adolescents in Norway, 2009–2018	10
Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy	9
Efficacy of cenobamate for uncontrolled focal seizures in patients with previous epilepsy-related surgery: Post hoc analysis of a phase 3, multicenter, open-label study	9
Automated preprocessing and phase-amplitude coupling analysis of scalp EEG discriminates infantile spasms from controls during wakefulness	9
Performance analysis of EEG seizure detection features	9
Impact of carbamazepine on vitamin D levels: A meta-analysis	9
Essential oil related seizures (EORS): A multi-center prospective study on essential oils and seizures in adults	9
Functional and structural connective disturbance of the primary and default network in patients with generalized tonic-clonic seizures	9
DDESVSFS: A simple, rapid and comprehensive screening tool for the Differential Diagnosis of Epileptic Seizures VS Functional Seizures	9
Dual/double pathology in neurocysticercosis causing drug resistant epilepsy – Chance association or causal?	9
Automated volumetry of hippocampal subfields in temporal lobe epilepsy	9
Role of pulse methylprednisolone in epileptic encephalopathy: A retrospective observational analysis	9
Electroclinical pattern in the transition from West to Lennox-Gastaut syndrome	9
Racial and ethnic trends in antiseizure medications trial enrolment: A systematic review using ClinicalTrials.gov	9
Contribution of rare genetic variants to drug response in absence epilepsy	9
Machine learning and statistic analysis to predict drug treatment outcome in pediatric epilepsy patients with tuberous sclerosis complex	8
White matter network disorder in mesial temporal epilepsy: An fMRI study	8
Effects of probiotics on GABA/glutamate and oxidative stress in PTZ- induced acute seizure model in rats	8
A systematic review and meta-analysis of the association of ABCC2/ABCG2 polymorphisms with antiepileptic drug responses in epileptic patients	8
Aphasic status epilepticus in a tertiary referral center in Turkey: Clinical features, etiology, and outcome	8
Feasibility of transcutaneous auricular vagus nerve stimulation in treatment of drug resistant epilepsy: A multicenter prospective study	8
Prevalence of comorbidities, and affective disorders in epilepsy: A latent class analysis approach	8
Associations between CYP3A4, CYP3A5 and SCN1A polymorphisms and carbamazepine metabolism in epilepsy: A meta-analysis	8
Evaluation of lorcaserin as an anticonvulsant in juvenile Fmr1 knockout mice	8
Characterization of spontaneous seizures and EEG abnormalities in a mouse model of the human A350V IQSEC2 mutation and identification of a possible target for precision medicine based therapy	8
Comparison of physical fitness, activity, and quality of life of the children with epilepsy and their healthy peers	8
Effect of counselling of parents of children with epilepsy focusing on sudden unexpected death in epilepsy	8
Effect of PIK3CA variants on glioma-related epilepsy and response to treatment	8
Precision treatment with nicotine in autosomal dominant sleep-related hypermotor epilepsy (ADSHE): An observational study of clinical outcome and serum cotinine levels in 17 patients	8
CYP2C19 & UGT1A6 genetic polymorphisms and the impact on Valproic acid-induced weight gain in people with epilepsy: Prospective genetic association study	8
Volumetric analysis of the piriform cortex in temporal lobe epilepsy	8
Artificial intelligence for medical image analysis in epilepsy	8
Thalamic neuromodulation for epilepsy: A clinical perspective	8
Evaluation of levocarnitine, lactulose, and combination therapy for the treatment of valproic acid-induced hyperammonemia in critically ill patients	8
Effects of ketogenic diet on cognitive function in pentylenetetrazol-kindled rats	7
Apparent diffusion coefficient is associated with seizure outcome after magnetic resonance-guided laser interstitial thermal therapy for mesial temporal lobe epilepsy	7
All that glitters: Contribution of stereo-EEG in patients with lesional epilepsy	7
The role of thalamic nuclei in genetic generalized epilepsies	7
Evaluation of psychiatric comorbidity in attention-deficit hyperactivity disorder with epilepsy: A case-control study	7
Epilepsy-associated increase in gonadotropin-releasing hormone neuron firing in diestrous female mice is independent of chronic seizure burden severity	7
Risk of sudden unexpected death in people with epilepsy and obstructive sleep apnea	7
Detection of preictal state in epileptic seizures using ensemble classifier	7
Investigation of dynamic functional connectivity of the source reconstructed epileptiform discharges in focal epilepsy: A graph theory approach	7
Acute physiologic prediction of pediatric post-traumatic epilepsy	7
Evaluation of the clinical characteristics of children with autism spectrum disorder and epilepsy and the perception of their parents on quality of life	7
Hippocampal low-frequency stimulation improves cognitive function in pharmacoresistant epileptic rats	7
18 F-FDG-PET hypometabolic pattern reveals multifocal epileptic foci despite limited unique stereotyped seizures	7
The effects of Hippophae rhamnoides in neuroprotection and behavioral alterations against iron-induced epilepsy	7
Analysis of intraoperative human brain tissue transcriptome reveals putative risk genes and altered molecular pathways in glioma-related seizures	7
Pregnancy outcomes of refractory epilepsy patients treated with Brain–responsive neurostimulation	7
Caregiver perspectives on dietary therapies for epilepsy	7
Comparison of subdural grid and stereoelectroencephalography in a cohort of pediatric patients	7
A framework for health equity in people living with epilepsy	7
Knowledge, Skills, and Attitudes Towards Children with Epilepsy Among Egyptian Parents: A Comparative Cross-Sectional Study	7
Role of anterior thalamic circuitry during sleep	7
Impact of a pharmacist-led education and counseling interventions on quality of life in epilepsy: A randomized controlled trial	7
Neuroimaging and thalamic connectomics in epilepsy neuromodulation	7
Association of ABCB1 polymorphisms with carbamazepine metabolism and resistance in epilepsy: A meta-analysis	7
Efficacy and safety of eslicarbazepine acetate as a first or later adjunctive therapy in patients with focal seizures	7

Efficacy and safety of traditional Chinese medicine for the treatment of epilepsy: A updated meta-analysis of randomized controlled trials	7
The clinical significance of small sharp spikes: A retrospective study of 909 patients in epilepsy monitoring unit	7
Fenfluramine treatment for Dravet syndrome: Caregiver- and clinician-reported benefits on the quality of life of patients, caregivers, and families living in Germany, Spain, Italy, and the United King	7
Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b+ Tyr Fmr1/J	7
The relationship between ecological executive function and stigma among patients with epilepsy: The mediating effect of social support	7
BCOR variants are associated with X-linked recessive partial epilepsy	7
Neural functional connectivity in patients with periventricular nodular heterotopia-mediated epilepsy	7
Effect of automatic injectors on the injection latency, safety, and seizure onset zone localization of ictal single photon emission computed tomography studies in adult epilepsy monitoring unit	6
How to inject ictal SPECT? From manual to automated injection	6
Physical activity status and quality of life in patients with epilepsy – Survey from level four epilepsy monitoring units	6
Flash-evoked high-frequency EEG oscillations in photosensitive epilepsies	6
Proteomic profile differentiating between mesial temporal lobe epilepsy with and without hippocampal sclerosis	6
Bioinformatics and network pharmacology analysis of drug targets and mechanisms related to the comorbidity of epilepsy and migraine	6
Cognitive outcomes following vagus nerve stimulation, responsive neurostimulation and deep brain stimulation for epilepsy: A systematic review	6
Cognitive outcomes following pediatric epilepsy surgery	6
Seizure outcomes in people with drug-resistant focal epilepsy evaluated for surgery but do not proceed	6
Deep learning-based diagnosis of temporal lobe epilepsy associated with hippocampal sclerosis: An MRI study	6
Efficacy of cenobamate by focal seizure subtypes: Post-hoc analysis of a phase 3, multicenter, open-label study	6
Effects of antiseizure medications on placental cells: Focus on heterodimeric placental carriers	6
Quantitative proteomic analysis to identify differentially expressed proteins in patients with epilepsy	6
Association between SCN1A polymorphism and carbamazepine responsiveness in epilepsy: A meta-analysis	6
The prefrontal cortex shows widespread decrease in H3 histamine receptor binding densities in rats with genetic generalized epilepsies	6
Efficacy of Brivaracetam in children with epilepsy	6
Machine learning model to predict the efficacy of antiseizure medications in patients with familial genetic generalized epilepsy	6
Ictal EEG in patients with autistic spectrum disorder and epilepsy	6
Localization of the epileptogenic zone based on ictal stereo-electroencephalogram: Brain network and single-channel signal feature analysis	6
Anticonvulsant activity of Nymphaea lotus Linn. extract in mice: The role of GABAergic-glutamatergic neurotransmission and antioxidant defence mechanisms	6
Instruments for investigation of epilepsy in low- and middle-income countries: A systematic review	6
Network meta-analysis of antiepileptic drugs in focal drug-resistant epilepsy	6
The role of stereo-electroencephalography to localize the epileptogenic zone in children with nonlesional brain magnetic resonance imaging	6
Long-term medical and social outcomes of patients with Lennox-Gastaut syndrome	6
A Phase 3 open-label study of the efficacy, safety and pharmacokinetics of buccally administered midazolam hydrochloride for the treatment of status epilepticus in pediatric Japanese subjects	6
Is the antiseizure effect of ketogenic diet in children with drug-resistant epilepsy mediated through proinflammatory cytokines?	6
Volumetric and microstructural abnormalities of the amygdala in focal epilepsy with varied levels of SUDEP risk	6
Post hoc analysis of a phase 3 study for treatment of uncontrolled focal seizures: Adjunctive cenobamate dose and seizure reduction by baseline seizure frequency	6
Feasibility of video/audio monitoring in the analysis of motion and treatment effects on night-time seizures – Interventional study	6
Single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis	6
Being physically active with epilepsy: Insights from young people and their parents	6
Epilepsy with Eyelid myoclonias − A diagnosis concealed in other genetic generalized epilepsies with photoparoxysmal response	6
Clinical and genetic characteristics of epilepsy of infancy with migrating focal seizures in Chinese children	6
Digoxin enhances the effect of antiepileptic drugs with different mechanism of action in the pentylenetetrazole-induced seizures in mice	6
Electroencephalography characteristics to predict one-year outcomes in pediatric anti-NMDA receptor encephalitis	6