OOIR: Observatory of International Research

Papers

(The TQCC of Epilepsy Research is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Morbidity Associated with Deviation from Pediatric Status Epilepticus Guidelines	42
The significance of interictal electroencephalogram analysis based on the grand total electroencephalogram score in early assessment of cognitive impairment in epilepsy patients	32
Risk of recurrence after a first unprovoked seizure with different risk factors: A 10-year prospective cohort study	31
Long-term musculoskeletal outcomes in pediatric hemispherotomy	31
SLC13A5 citrate transporter disorder epilepsy phenotype	29
Allostatic load of immune cells in the spleen and brain of the Kcna1-null mouse model of temporal lobe epilepsy	26
Relation between orexin A and epileptic seizures	26
Sudden unexpected death in epilepsy (SUDEP): A bibliometric analysis	24
Quantitative electroencephalographic analysis as a potential biomarker of response to treatment with cannabidiol	24
Differential electrographic seizure patterns in malformations of cortical development, early life brain injury, and later life brain injury	23
Development and validation of a predictive model assessing the risk of seizure recurrence in children with neurocysticercosis	23
Volumetric and microstructural abnormalities of the amygdala in focal epilepsy with varied levels of SUDEP risk	21
Optimizing drug-resistant epilepsy identification in the Veterans Health Administration	20
Treatment of pediatric drug-resistant generalized epilepsy with responsive neurostimulation of the centromedian nucleus of the thalamus: A case series of seven patients	20
Blood-brain barrier targeted delivery of lacosamide-conjugated gold nanoparticles: Improving outcomes in absence seizures	19
Recruitment of interictal- and ictal-like discharges in posterior piriform cortex by delta-rate (1–4 Hz) focal bursts in anterior piriform cortex in vivo	19
Adherence and discontinuation of prescription cannabidiol for the management of seizure disorders at an integrated care center	19
Exploring seizure characteristics in individuals with autoimmune encephalitis: A comprehensive retrospective study in a low-middle-income country setting	19
Turning data analytics into an organisational asset: A landscape population analysis of 5720 people with epilepsy attending outpatient care in Ireland	18
Pharmacological evaluation of E2730, a novel selective uncompetitive GAT1 inhibitor, on epileptiform activities in resected brain tissues from human focal cortical dysplasia ex vivo	18
Protocols for multimodal polygraphy for cardiorespiratory monitoring in the epilepsy monitoring unit. Part I: Clinical acquisition	18
Epilepsy in neurofibromatosis type 1: Prevalence, phenotype, and genotype in adults	17
Antiepileptogenic and neuroprotective effect of mefloquine after experimental status epilepticus	17
“Virtual patch clamp analysis” for predicting the functional significance of pathogenic variants in sodium channels	16
Psychological and health-related quality of life outcomes in children with developmental and epileptic encephalopathy with spike-wave activation in sleep (D/EE-SWAS): A single-center prospective study	16

Long-term seizure diary tracking habits in clinical studies: Evidence from the Human Epilepsy Project	16
A side-by-side comparison of fine-tuning options for treatment of medically refractory epilepsy: Antiseizure medications, vagus nerve stimulation and ketogenic diet therapies	16
Development and validation of an interpretable machine learning model for predicting post-stroke epilepsy	16
Luteolin ameliorates pentetrazole-induced seizures through the inhibition of the TLR4/NF-κB signaling pathway	16
Twenty-four-hour pattern of children with febrile seizures presenting to a United States Pediatric Emergency Department	16
Cannabis derivatives and their synthetic analogs for treatment-resistant epilepsy: A systematic review and meta-analysis	15
Editorial Board	15
Progressive generalized tonic-clonic seizures in a transgenic mouse model of adult-onset epilepsy: Implications for morphological changes in cortico-limbic and brainstem structures	15
Elucidating the visual phenomena in epilepsy: A mini review	14
Epilepsy panels in clinical practice: Yield, variants of uncertain significance, and treatment implications	14
Significant reduction of seizure frequency in patients with drug-resistant epilepsy by vagus nerve stimulation: Systematic review and meta-analysis	14
Leat-associated seizures the possible role of EAAT2, pyruvate carboxylase and glutamine synthetase	14
Cathodal HD-tDCS and attention: A study on patients with intractable left lateral frontal lobe epilepsy	14
Deep brain stimulation for epilepsy: A systematic review and meta-analysis of randomized and non-randomized studies of thalamic targeting	14
Neural hyperexcitability in Angelman syndrome: Genetic factors and pharmacologic treatment approaches	14
Impact of valproate therapy on timing of puberty in adolescents with childhood-onset epilepsy	13
Mobile health applications for epilepsy in Indian app stores: A systematic review and content analysis using the mobile app rating scale	13
Adapting a measure of gross motor skills for individuals with CDKL5 deficiency disorder: A psychometric study	13
Acute physiologic prediction of pediatric post-traumatic epilepsy	13
Effects of acute administration of 4-allyl-2,6-dimethoxyphenol in mouse models of seizures	13
Impact of the economic crisis in Sri Lanka on health and healthcare related to epilepsy	12
Optimally targeting the centromedian nucleus of the thalamus for generalized epilepsy: A meta-analysis	12
Editorial Board	12
A framework for health equity in people living with epilepsy	12
Protein profiling in plasma for biomarkers of seizure	12
SEEG guided mapping of primary motor cortex in children with epilepsy	12
A universal method for seizure onset zone localization in focal epilepsy using standard deviation of spike amplitude	11
Effects of probiotics on GABA/glutamate and oxidative stress in PTZ- induced acute seizure model in rats	11
Amygdala enlargement in pediatric epilepsy: A clinically meaningful finding?	11
The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study	11
Seizure and cognitive outcomes of cortical long bursting responsive neurostimulation in intractable focal epilepsy	11
Oligoepilepsy and lifelong seizure susceptibility in epilepsy with generalized tonic-clonic seizures alone: Experience at an adult tertiary center	11
Landscaping evidence on first-line therapies for infantile epileptic spasms syndrome: An umbrella review	11
Advancing thalamic neuromodulation in epilepsy: Bridging adult data to pediatric care	11
Adequate and inadequate dosing of anti-seizure medications in status epilepticus	11
Fear of sleep in people with epilepsy	11
Assessing an fMRI-guided titration paradigm for microburst VNS therapy	11
Interictal epileptiform discharges as the most significant confounding factor underlying memory impairment in focal epilepsy	11
Editorial Board	11
Arousal deregulation in the co-shaping of neuropsychological dysfunction in frontal and mesial temporal lobe epilepsy	11
Frontoparietal 18F-FDG-PET hypo-metabolism in Lennox-Gastaut syndrome: Further evidence highlighting the key network	10
Influence of executive functions on quality of life in Pediatric Epilepsy: A cross-sectional study	10
Nonadherence to antiepileptic medication and associated factors among persons with epilepsy in India: A systematic review and meta-analysis	10
Posttraumatic epilepsy: Integrating clinical, inflammatory, and genetic profiles in traumatic brain injury patients	10
Corrigendum to “A systematic review of highly purified cannabidiol in developmental and epileptic encephalopathies and complex treatment-resistant epilepsies: Changes in seizure frequency and adverse	10
Machine learning models for predicting therapeutic response in drug-resistant epilepsy: A bivariate diagnostic meta-analysis	10
A model of new-onset refractory status epilepticus (NORSE) using intrahippocampal kainic acid in adolescent mice	10
Evaluation and clinical characteristics of anxiety, depression, and sleep quality among adult patients with seizure clusters	10
The role of interleukin-17 in epilepsy	10
Temporal and spatial changes in synaptic vesicle glycoprotein 2A (SV2A) under kainic acid induced epileptogenesis: An autoradiographic study	10

Clinical and EEG characteristics of sleep-related hypermotor epilepsy in children	10
Depressive symptoms in Chinese patients with epilepsy: Prevalence and clinical correlates	10
mTOR and HDAC2 are simultaneously activated during electrically induced kindling of seizures	10
Quantitative analysis of the morphometric analysis program MAP in patients with truly MRI-negative focal epilepsy	9
Editorial Board	9
The suppressive effect of the specific KCC2 modulator CLP290 on seizure in mice	9
Rapid intravenous loading of brivaracetam during invasive and non-invasive video-EEG monitoring	9
HFA analysis using scalp electroencephalograms in two cases of Rasmussen’s syndrome	9
Corrigendum to “The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study” [Epilepsy Res. 190 (2023) 107099]	9
Whole exome sequencing identifies variable expressivity of CLN6 variants in Progressive myoclonic epilepsy affected families	9
Time-dependent risk of stroke following epilepsy: A nationwide cohort study in South Korea	9
Stereo-EEG localization of midline onset seizures on scalp EEG	9
The SEEG brain network predicts epileptic surgical outcomes of radiofrequency thermocoagulation	9
Interobserver reliability of a recently proposed semiological classification in psychogenic nonepileptic seizures in children	9
Detection of short-lasting and ictal spike-and-wave discharges in around-the-ears EEG recordings in children with absence epilepsy	9
Predictors of surgical outcome in frontal lobe epilepsy: Experience from a single-center cohort in Latin America	9
Health insurance and transportation barriers impact access to epilepsy care in the United States	8
SUDEP: Living with the knowledge	8
The relationship between environmental air pollution, meteorological factors, and emergency service admissions for epileptic attacks in children	8
Individuals’ invisible work continues after epilepsy surgery: A qualitative interview study	8
Catatonia associated with epileptic seizures: A systematic review of case reports	8
Neuropsychological characteristics of drug resistant epilepsy patients with and without comorbid functional seizures	8
Transcranial magnetic stimulation and magnetoencephalography are feasible alternatives to invasive methods in optimizing responsive neurostimulation device placement	8
A replicable, open-source, data integration method to support national practice-based research & quality improvement systems	8
Editorial Board	8
MicroRNAs as potential biomarkers of response to modified Atkins diet in treatment of adults with drug-resistant epilepsy: A proof-of-concept study	8
Effect of counselling of parents of children with epilepsy focusing on sudden unexpected death in epilepsy	8
Text integration processes in children with Childhood Epilepsy with Centro-Temporal Spikes	8
The treatment of epilepsy in younger and older adults: Demographic differences and prescribing patterns of anti-seizure medications in Canada	8
Microtubule-stabilizing drugs suppress convulsions in a C. elegans model of CAMSAP disorders	8
Epilepsy in children and adolescents with B-cell acute lymphoblastic leukemia	8
The contribution of sleep and co-occurring neurodevelopmental conditions to quality of life in children with epilepsy	8
Impact of JME on quality of life: Does a well-controlled epilepsy also hamper the psychological wellbeing?	8
Reduced epilepsy development in synapsin 2 knockout mice with autistic behavior following early systemic treatment with interleukin-6 receptor antibody	8
The teratogenesis risk associated with antiseizure medication duotherapy in women with epilepsy	8
Influence of weather regime and local geomagnetic activity on the occurrence of epileptic seizures	8
Editorial Board	8
A simple and reliable electroencephalogram montage for detecting and managing electrographic seizures in children with acute encephalitis and encephalopathy	8
Early versus late switch over of antiseizure medications from intravenous to the oral route in children with seizures: Single-blinded, randomized controlled trial (ELAIO trial)	7
Differential impact of a ghrelin receptor antagonist or inverse agonist in the electrical kindling model of epilepsy	7
Editorial Board	7
The development, content and response process validation of a caregiver-reported severity measure for CDKL5 deficiency disorder	7
Factors linked with perceived stigma amid people with Epilepsy -across sectional study	7
Effect of intracerebroventricular administration of alglucosidase alfa in two mouse models of Lafora disease: Relevance for clinical practice	7
Challenges to epilepsy surgery referral in Mexico: Results from a nationwide survey of primary care physicians and specialists	7
Elevated body temperature affects spike-and-wave discharges and induces behavioural deficits in genetic absence epilepsy rats	7
Functional brain network analysis using electroencephalography in late-onset Lennox–Gastaut syndrome	7
Extensive pharmacokinetic variability of Levetiracetam. ¿Are doctors aware?	7
Lestaurtinib (CEP-701) reduces the duration of limbic status epilepticus in periadolescent rats	7
Surgery for epilepsy secondary to vascular insults: A systematic review and meta-analysis of individual patient data	7
Phase 2, placebo-controlled clinical study of oral ganaxolone in PCDH19-clustering epilepsy	7
AI in ECG: Validating an ambulatory semiology labeller and predictor	7
Intrathecal application of ethosuximide is highly efficient in suppressing seizures in a genetic model of absence epilepsy	7
A systematic review of artificial intelligence techniques based on electroencephalography analysis in the diagnosis of epilepsy disorders: A clinical perspective	7
Efficacy of felbamate in a cohort of patients with epilepsy with myoclonic atonic seizures (EMAtS)	7
Efficacy of transcutaneous vagus nerve stimulation (t-VNS) in treating drug-resistant epilepsy: A systematic review and meta-analysis	7
Application of inverted brain region-specific error vectors can improve spatial accuracy of clinical electrical source imaging	7
Prediction of epilepsy surgery outcome using foramen ovale EEG – A machine learning approach	6
Beyond seizure freedom: Reduction in anti-seizure medication after epilepsy surgery	6
Do germline genetic variants influence surgical outcomes in drug-resistant epilepsy?	6
Action potential-dependent α4-containing GABAA receptors contribute to epileptogenicity in focal cortical dysplasia	6
Anatomical-electroclinical phenotypes and SEEG-defined network patterns in pure insular lobe epilepsy: A study of 20 cases	6
Mapping the neural circuits responding to deep brain stimulation of the anterior nucleus of the thalamus in the rat brain	6
The relationship between disease self-management and internalized stigmatization in individuals with epilepsy: A sample in eastern Turkey	6
The impact of antiseizure medication on bone health: A systematic review of animal studies	6
Impact of pediatric epilepsy on sleep architecture: A systematic review and meta-analysis	6
Maximal Electroconvulsive Shock-Induced Seizures Elicit Long-Lasting Analgesia and Short-Lasting Hyperoxia in a Sex Dependent Manner	6
EEG based oculographic analysis of epileptic nystagmus	6
Mendelian randomization approach shows no causal effects of gestational age on epilepsy in offspring	6
Use of oral anti-seizure medication via nasogastric tube to treat IV-diazepam resistant status epilepticus in a setting with limited resources: An observational study	6
Examination of psychological resilience and self-esteem in adolescents having siblings with epilepsy	6
Four-Way Wada: SEEG-based mapping with electrical stimulation, high frequency activity, and phase amplitude coupling to complement traditional Wada and functional MRI prior to epilepsy surgery	6
Natural history of epilepsy in FOXG1 Syndrome	6
Outcomes of surgically and non-surgically managed temporal encephalocoeles in the context of drug-resistant temporal lobe epilepsy: A retrospective single-centre case series	6
Neuropsychological function in psychosis of epilepsy	6
Editorial Board	6
Suicidal ideation among Nigerian patients with epilepsy	6