Epilepsy Research

Article	Citations
Morbidity Associated with Deviation from Pediatric Status Epilepticus Guidelines	42
The significance of interictal electroencephalogram analysis based on the grand total electroencephalogram score in early assessment of cognitive impairment in epilepsy patients	34
Optimizing drug-resistant epilepsy identification in the Veterans Health Administration	32
Long-term musculoskeletal outcomes in pediatric hemispherotomy	31
Differential electrographic seizure patterns in malformations of cortical development, early life brain injury, and later life brain injury	31
Treatment of pediatric drug-resistant generalized epilepsy with responsive neurostimulation of the centromedian nucleus of the thalamus: A case series of seven patients	28
Risk of recurrence after a first unprovoked seizure with different risk factors: A 10-year prospective cohort study	26
SLC13A5 citrate transporter disorder epilepsy phenotype	25
Relation between orexin A and epileptic seizures	24
Quantitative electroencephalographic analysis as a potential biomarker of response to treatment with cannabidiol	23
Sudden unexpected death in epilepsy (SUDEP): A bibliometric analysis	23
Allostatic load of immune cells in the spleen and brain of the Kcna1-null mouse model of temporal lobe epilepsy	23
Development and validation of a predictive model assessing the risk of seizure recurrence in children with neurocysticercosis	21
Volumetric and microstructural abnormalities of the amygdala in focal epilepsy with varied levels of SUDEP risk	21
Blood-brain barrier targeted delivery of lacosamide-conjugated gold nanoparticles: Improving outcomes in absence seizures	21
Twenty-four-hour pattern of children with febrile seizures presenting to a United States Pediatric Emergency Department	20
Adherence and discontinuation of prescription cannabidiol for the management of seizure disorders at an integrated care center	20
Pharmacological evaluation of E2730, a novel selective uncompetitive GAT1 inhibitor, on epileptiform activities in resected brain tissues from human focal cortical dysplasia ex vivo	19
Exploring seizure characteristics in individuals with autoimmune encephalitis: A comprehensive retrospective study in a low-middle-income country setting	19
Epilepsy in neurofibromatosis type 1: Prevalence, phenotype, and genotype in adults	19
Recruitment of interictal- and ictal-like discharges in posterior piriform cortex by delta-rate (1–4 Hz) focal bursts in anterior piriform cortex in vivo	18
Turning data analytics into an organisational asset: A landscape population analysis of 5720 people with epilepsy attending outpatient care in Ireland	18
Long-term seizure diary tracking habits in clinical studies: Evidence from the Human Epilepsy Project	18
Luteolin ameliorates pentetrazole-induced seizures through the inhibition of the TLR4/NF-κB signaling pathway	17
Neuroimaging and thalamic connectomics in epilepsy neuromodulation	17

A side-by-side comparison of fine-tuning options for treatment of medically refractory epilepsy: Antiseizure medications, vagus nerve stimulation and ketogenic diet therapies	16
Antiepileptogenic and neuroprotective effect of mefloquine after experimental status epilepticus	16
Progressive generalized tonic-clonic seizures in a transgenic mouse model of adult-onset epilepsy: Implications for morphological changes in cortico-limbic and brainstem structures	16
Development and validation of an interpretable machine learning model for predicting post-stroke epilepsy	16
“Virtual patch clamp analysis” for predicting the functional significance of pathogenic variants in sodium channels	16
Protocols for multimodal polygraphy for cardiorespiratory monitoring in the epilepsy monitoring unit. Part I: Clinical acquisition	16
Epilepsy panels in clinical practice: Yield, variants of uncertain significance, and treatment implications	15
Significant reduction of seizure frequency in patients with drug-resistant epilepsy by vagus nerve stimulation: Systematic review and meta-analysis	15
Alterations in aortic vasorelaxation in rats with epilepsy induced by the electrical amygdala kindling model	15
Neural hyperexcitability in Angelman syndrome: Genetic factors and pharmacologic treatment approaches	15
Cathodal HD-tDCS and attention: A study on patients with intractable left lateral frontal lobe epilepsy	15
Deep brain stimulation for epilepsy: A systematic review and meta-analysis of randomized and non-randomized studies of thalamic targeting	14
Leat-associated seizures the possible role of EAAT2, pyruvate carboxylase and glutamine synthetase	14
Elucidating the visual phenomena in epilepsy: A mini review	14
Cannabis derivatives and their synthetic analogs for treatment-resistant epilepsy: A systematic review and meta-analysis	14
Effects of acute administration of 4-allyl-2,6-dimethoxyphenol in mouse models of seizures	14
Editorial Board	14
Mobile health applications for epilepsy in Indian app stores: A systematic review and content analysis using the mobile app rating scale	14
Acute physiologic prediction of pediatric post-traumatic epilepsy	14
Adapting a measure of gross motor skills for individuals with CDKL5 deficiency disorder: A psychometric study	14
Editorial Board	13
Impact of valproate therapy on timing of puberty in adolescents with childhood-onset epilepsy	13
Protein profiling in plasma for biomarkers of seizure	13
Interictal epileptiform discharges as the most significant confounding factor underlying memory impairment in focal epilepsy	13
Optimally targeting the centromedian nucleus of the thalamus for generalized epilepsy: A meta-analysis	13
Impact of the economic crisis in Sri Lanka on health and healthcare related to epilepsy	13
SEEG guided mapping of primary motor cortex in children with epilepsy	12
A framework for health equity in people living with epilepsy	12
A universal method for seizure onset zone localization in focal epilepsy using standard deviation of spike amplitude	12
Editorial Board	12
Oligoepilepsy and lifelong seizure susceptibility in epilepsy with generalized tonic-clonic seizures alone: Experience at an adult tertiary center	12
Fear of sleep in people with epilepsy	12
Assessing an fMRI-guided titration paradigm for microburst VNS therapy	12
Advancing thalamic neuromodulation in epilepsy: Bridging adult data to pediatric care	11
Editorial Board	11
Landscaping evidence on first-line therapies for infantile epileptic spasms syndrome: An umbrella review	11
Depressive symptoms in Chinese patients with epilepsy: Prevalence and clinical correlates	11
Effects of probiotics on GABA/glutamate and oxidative stress in PTZ- induced acute seizure model in rats	11
The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study	11
Seizure and cognitive outcomes of cortical long bursting responsive neurostimulation in intractable focal epilepsy	11
Corrigendum to “A systematic review of highly purified cannabidiol in developmental and epileptic encephalopathies and complex treatment-resistant epilepsies: Changes in seizure frequency and adverse	11
Posttraumatic epilepsy: Integrating clinical, inflammatory, and genetic profiles in traumatic brain injury patients	11
Adequate and inadequate dosing of anti-seizure medications in status epilepticus	11
Interobserver reliability of a recently proposed semiological classification in psychogenic nonepileptic seizures in children	11
Arousal deregulation in the co-shaping of neuropsychological dysfunction in frontal and mesial temporal lobe epilepsy	11
Editorial Board	10
Influence of executive functions on quality of life in Pediatric Epilepsy: A cross-sectional study	10
Evaluation and clinical characteristics of anxiety, depression, and sleep quality among adult patients with seizure clusters	10
Nonadherence to antiepileptic medication and associated factors among persons with epilepsy in India: A systematic review and meta-analysis	10
Rapid intravenous loading of brivaracetam during invasive and non-invasive video-EEG monitoring	10

A model of new-onset refractory status epilepticus (NORSE) using intrahippocampal kainic acid in adolescent mice	10
Clinical and EEG characteristics of sleep-related hypermotor epilepsy in children	10
Frontoparietal 18F-FDG-PET hypo-metabolism in Lennox-Gastaut syndrome: Further evidence highlighting the key network	10
Dravet syndrome in children—A population-based study	10
Machine learning models for predicting therapeutic response in drug-resistant epilepsy: A bivariate diagnostic meta-analysis	10
Temporal and spatial changes in synaptic vesicle glycoprotein 2A (SV2A) under kainic acid induced epileptogenesis: An autoradiographic study	10
The role of interleukin-17 in epilepsy	10
mTOR and HDAC2 are simultaneously activated during electrically induced kindling of seizures	10
Stereo-EEG localization of midline onset seizures on scalp EEG	9
HFA analysis using scalp electroencephalograms in two cases of Rasmussen’s syndrome	9
Editorial Board	9
MicroRNAs as potential biomarkers of response to modified Atkins diet in treatment of adults with drug-resistant epilepsy: A proof-of-concept study	9
Quantitative analysis of the morphometric analysis program MAP in patients with truly MRI-negative focal epilepsy	9
Predictors of surgical outcome in frontal lobe epilepsy: Experience from a single-center cohort in Latin America	9
Time-dependent risk of stroke following epilepsy: A nationwide cohort study in South Korea	9
The relationship between environmental air pollution, meteorological factors, and emergency service admissions for epileptic attacks in children	9
The SEEG brain network predicts epileptic surgical outcomes of radiofrequency thermocoagulation	9
Corrigendum to “The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study” [Epilepsy Res. 190 (2023) 107099]	9
Catatonia associated with epileptic seizures: A systematic review of case reports	9
The teratogenesis risk associated with antiseizure medication duotherapy in women with epilepsy	9
Impact of JME on quality of life: Does a well-controlled epilepsy also hamper the psychological wellbeing?	9
Text integration processes in children with Childhood Epilepsy with Centro-Temporal Spikes	8
AI in ECG: Validating an ambulatory semiology labeller and predictor	8
Early versus late switch over of antiseizure medications from intravenous to the oral route in children with seizures: Single-blinded, randomized controlled trial (ELAIO trial)	8
A simple and reliable electroencephalogram montage for detecting and managing electrographic seizures in children with acute encephalitis and encephalopathy	8
Individuals’ invisible work continues after epilepsy surgery: A qualitative interview study	8
Detection of short-lasting and ictal spike-and-wave discharges in around-the-ears EEG recordings in children with absence epilepsy	8
Reduced epilepsy development in synapsin 2 knockout mice with autistic behavior following early systemic treatment with interleukin-6 receptor antibody	8
Epilepsy in children and adolescents with B-cell acute lymphoblastic leukemia	8
Editorial Board	8
Efficacy of felbamate in a cohort of patients with epilepsy with myoclonic atonic seizures (EMAtS)	8
Influence of weather regime and local geomagnetic activity on the occurrence of epileptic seizures	8
The treatment of epilepsy in younger and older adults: Demographic differences and prescribing patterns of anti-seizure medications in Canada	8
SUDEP: Living with the knowledge	8
The suppressive effect of the specific KCC2 modulator CLP290 on seizure in mice	8
A replicable, open-source, data integration method to support national practice-based research & quality improvement systems	8
Transcranial magnetic stimulation and magnetoencephalography are feasible alternatives to invasive methods in optimizing responsive neurostimulation device placement	8
Effect of counselling of parents of children with epilepsy focusing on sudden unexpected death in epilepsy	8
Lestaurtinib (CEP-701) reduces the duration of limbic status epilepticus in periadolescent rats	8
Neuropsychological characteristics of drug resistant epilepsy patients with and without comorbid functional seizures	8
Whole exome sequencing identifies variable expressivity of CLN6 variants in Progressive myoclonic epilepsy affected families	8
The contribution of sleep and co-occurring neurodevelopmental conditions to quality of life in children with epilepsy	8
Health insurance and transportation barriers impact access to epilepsy care in the United States	8
Challenges to epilepsy surgery referral in Mexico: Results from a nationwide survey of primary care physicians and specialists	7
The relationship between disease self-management and internalized stigmatization in individuals with epilepsy: A sample in eastern Turkey	7
Natural history of epilepsy in FOXG1 Syndrome	7
Suicidal ideation among Nigerian patients with epilepsy	7
Do germline genetic variants influence surgical outcomes in drug-resistant epilepsy?	7
Action potential-dependent α4-containing GABAA receptors contribute to epileptogenicity in focal cortical dysplasia	7
Four-Way Wada: SEEG-based mapping with electrical stimulation, high frequency activity, and phase amplitude coupling to complement traditional Wada and functional MRI prior to epilepsy surgery	7
Surgery for epilepsy secondary to vascular insults: A systematic review and meta-analysis of individual patient data	7
Phase 2, placebo-controlled clinical study of oral ganaxolone in PCDH19-clustering epilepsy	7
Can bilingualism increase neuroplasticity of language networks in epilepsy?	7
Intrathecal application of ethosuximide is highly efficient in suppressing seizures in a genetic model of absence epilepsy	7
Extensive pharmacokinetic variability of Levetiracetam. ¿Are doctors aware?	7
Functional brain network analysis using electroencephalography in late-onset Lennox–Gastaut syndrome	7
Impact of pediatric epilepsy on sleep architecture: A systematic review and meta-analysis	7
Prediction of epilepsy surgery outcome using foramen ovale EEG – A machine learning approach	7
Editorial Board	7
Efficacy of transcutaneous vagus nerve stimulation (t-VNS) in treating drug-resistant epilepsy: A systematic review and meta-analysis	7
The development, content and response process validation of a caregiver-reported severity measure for CDKL5 deficiency disorder	7
Application of inverted brain region-specific error vectors can improve spatial accuracy of clinical electrical source imaging	7
Differential impact of a ghrelin receptor antagonist or inverse agonist in the electrical kindling model of epilepsy	7
A systematic review of artificial intelligence techniques based on electroencephalography analysis in the diagnosis of epilepsy disorders: A clinical perspective	7
Editorial Board	7
Beyond seizure freedom: Reduction in anti-seizure medication after epilepsy surgery	7
Examination of psychological resilience and self-esteem in adolescents having siblings with epilepsy	7
The impact of antiseizure medication on bone health: A systematic review of animal studies	7
Factors linked with perceived stigma amid people with Epilepsy -across sectional study	7
Effect of intracerebroventricular administration of alglucosidase alfa in two mouse models of Lafora disease: Relevance for clinical practice	7
Mapping the neural circuits responding to deep brain stimulation of the anterior nucleus of the thalamus in the rat brain	6
Outcomes of surgically and non-surgically managed temporal encephalocoeles in the context of drug-resistant temporal lobe epilepsy: A retrospective single-centre case series	6
Use of oral anti-seizure medication via nasogastric tube to treat IV-diazepam resistant status epilepticus in a setting with limited resources: An observational study	6
EEG based oculographic analysis of epileptic nystagmus	6
Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective	6
The anti-seizure potential of cysteine leukotriene receptor antagonists: A systematic review of animal studies	6
Mendelian randomization approach shows no causal effects of gestational age on epilepsy in offspring	6
Neuropsychological function in psychosis of epilepsy	6
Executive functioning and social skills in children with epileptic seizures and non-epileptic seizures	6
Validation of hemispherectomy outcome prediction scale in treatment of medically intractable epilepsy	6

Inherited SCN1A missense mutation in a Dravet Syndrome family: Neuropathological correlation, family screening and implications for adult carriers	6
N-acetyl cysteine: A new look at its effect on PTZ-induced convulsions	6
Aerobic exercise, alone or combined with an anti-inflammatory drug, reduces the severity of epileptic seizures and levels of central pro-inflammatory cytokines in an animal model of epileptic seizures	6
Anatomical-electroclinical phenotypes and SEEG-defined network patterns in pure insular lobe epilepsy: A study of 20 cases	6
Shaping the future of European epilepsy research: Final meeting report from EPICLUSTER	6
Kindling in humans: Does secondary epileptogenesis occur?	6
Retention rate of vagus nerve stimulation for the treatment of drug-resistant epilepsy: A single-centre, retrospective study.	6
The health care costs of epilepsy: Evidence from all-payer claims data	6
Effect of trans 4-butylcyclohexane carboxylic acid (4-BCCA) upon neurodegeneration, oxidative stress related to epileptogenesis in pilocarpine-induced status epilepticus	5
Clinical and hematologic predictors of early intensive care unit admission in seizure patients presenting to the emergency room	5
Effect of UGT1A4, UGT2B7, UGT2B15, UGT2B17 and ABC1B polymorphisms on lamotrigine metabolism in Danish patients	5
A nationwide study of initiation of antidepressant pharmacotherapy and the risk of seizures	5
Clinical and sociodemographic characteristics of patients with epilepsy attended at a regional reference psychiatric emergency unit	5
The fate of spikes in self-limited epilepsy with centrotemporal spikes: Are clinical and baseline EEG features effective?	5
Long-term efficacy and safety of perampanel as an add-on therapy in patients with epilepsy	5
Independent evaluation of deep learning models for detecting focal cortical dysplasia	5
Persistent Kv7.2/7.3 downregulation in the rat pilocarpine model of mesial temporal lobe epilepsy	5
Network analysis reveals a role of the hippocampus in absence seizures: The effects of a cannabinoid agonist	5
Predicting seizure-free outcomes in people with treatment-resistant epilepsy: A machine learning approach	5
Use of benzodiazepines in patients with status epilepticus requiring second-line antiseizure medication treatment	5
Comment on the meta-analysis comparing phenobarbital and valproate for the treatment of generalized convulsive status epilepticus	5
Early-phase EEG power spectrum analysis may differentiate acute encephalopathy with biphasic seizures and late reduced diffusion from prolonged febrile seizures	5
In-hospital outcomes in people with autism and epilepsy – A population-based study	5
The influence of disease course and surgery on quality of life in children with focal cortical dysplasia and long-term epilepsy-associated tumours: A systematic review and meta-analysis	5
Enteral topiramate treatment in refractory status epilepticus	5
A comprehensive narrative review of epilepsy with eyelid myoclonia	5
Pharmacokinetics of cenobamate as monotherapy compared with adjunctive therapy	5
Phenylbutyrate for monogenetic epilepsy: Literature review	5
Experiences of adults living with refractory epilepsy and their views and expectations on receiving results from whole genome sequencing	5
Face–name associative memory in temporal lobe epilepsy: Region-specific insights in right-hemisphere onset	5
Predicting efficacy of antiseizure medication treatment with machine learning algorithms in North Indian population	5
Evaluation of epilepsy in 8p-related disorders	5
Challenges in epilepsy diagnosis and management in a low-resource setting: An experience from Bhutan	5
Current practice and safety measures in epilepsy monitoring units in the Gulf Cooperation Council Countries: A cross-sectional study	5
Tenets of timing: An evidence based comprehensive review on time-lag in the management of pediatric status epilepticus and its effect on clinical outcomes	5
Trends, prescribing patterns and projections of antiseizure drug use in Europe	5
SYNGAP-1 developmental and epileptic encephalopathy: Utility of corpus callosotomy and neuromodulation	5
Patient, parent and carer perspectives surrounding expedited paediatric epilepsy surgery	5
Ganaxolone in Epilepsy: Insights into a Neurosteroid-Based Therapy	5
Machine learning and statistic analysis to predict drug treatment outcome in pediatric epilepsy patients with tuberous sclerosis complex	5
Experience of waiting for seizure freedom and perception of machine learning technologies to support treatment decision: A qualitative study in adults with recent onset epilepsy	4
Development and prospective clinical validation of a convolutional neural network for automated detection and segmentation of focal cortical dysplasias	4
Caloric restriction: Anti-inflammatory and antioxidant mechanisms against epileptic seizures	4
Primary prophylaxis of seizures in post-hemorrhagic stroke rehabilitation patients	4
Editorial Board	4
Brain network reconstruction of abnormal functional connectivity in Lennox-Gastaut syndrome according to drug responsiveness: A retrospective study	4
Epilepsy Arabic renaming to cerebroelectric disorder could minimize the stigma	4
Evaluation of intravenous lorazepam dosing strategies and the incidence of refractory status epilepticus	4
Serum levels of matrix metalloproteinase 2 and its inhibitor after tonic-clonic seizures	4
Serum concentration of high-mobility group box 1, Toll-like receptor 4 as biomarker in epileptic patients	4
Editorial Board	4
Feasibility of video/audio monitoring in the analysis of motion and treatment effects on night-time seizures – Interventional study	4
Can heart rate variability identify a high-risk state of upcoming seizure?	4
Effects of treatment with clinically relevant valproate, carbamazepine, oxcarbazepine, topiramate, lamotrigine and levetiracetam on ovarian folliculogenesis in young rats	4
Principal component analysis of antiseizure medication-induced hostility/aggression and factor analysis of levetiracetam using the food and drug administration adverse event reporting system	4
Editorial Board	4
Long-term efficacy and safety of perampanel monotherapy in patients with newly diagnosed or currently untreated recurrent focal-onset seizures: Results from the open-label extension phase of FREEDOM (	4
Corrigendum to “An rs-fMRI based neuroimaging marker for adult absence epilepsy” [2024 204, 107400]	4
Investigating anti-inflammatory and immunomodulatory properties of brivaracetam and lacosamide in experimental autoimmune encephalomyelitis (EAE)	4
Image-guided posterior callosotomy: Optimizing disconnection with DTI tractography and neuronavigation	4
Re-exploring the relationship between skull thickness and alpha asymmetry: A CT/MR imaging correlation study	4
Editorial Board	4
Editorial Board	4
Effect of low frequency stimulation of olfactory bulb on seizure severity, learning, and memory in kindled rats	4
Quality indicators for epilepsy management in China: The development of a tool to assess care and first three-year report	4
Perceived stigma and self-esteem for children with epilepsy	4
The stigma paradox: Perception of quality-of-life in people with epilepsy among themselves, the family, and the general population in Indonesian urban areas	4
Late onset epilepsy findings in a developmental country, a report of first results	4
Anti-epileptogenic effects of synaptic vesicle protein 2A modulation in a mouse model of Alzheimer’s disease	4
Pragmatic strategies for improving prevention, diagnosis, and treatment of epilepsy in low- and middle-income countries	4
Protocols for multimodal polygraphy for cardiorespiratory monitoring in the epilepsy monitoring unit. Part II – Research acquisition	4
Post‑stroke seizure and epilepsy after intravenous alteplase: A retrospective cohort with SeLECT score profiling	4
Assessment of auditory perception abilities using temporal envelope and fine structure processing in children with self-limited epilepsy with centrotemporal spikes	4
Effect of adropin on seizure activity in rats with penicillin-induced epilepsy	4
Maternal pre-pregnancy body mass index, gestational weight gain and epilepsy in the offspring: A population-based cohort study	4
Editorial Board	4
The characterization of psychosis and response to antipsychotic therapy in monogenic forms of familial focal epilepsy: A systematic review	4
Editorial Board	4
NS-Pten knockout mice exhibit sex and hippocampal subregion-specific increases in microglia/macrophage density	4
Addressing the gap: SUDEP knowledge and communication among patients and neurologists	4
Kv5.1 antibody in epilepsy patients with unknown etiology	4
The prefrontal cortex shows widespread decrease in H3 histamine receptor binding densities in rats with genetic generalized epilepsies	4
Altered synaptic functions in a humanized mouse model of down syndrome (TcMAC21): Implications for seizure susceptibility	3
Evaluating the late seizures of acute encephalopathy with biphasic seizures and late reduced diffusion via monitoring using continuous electroencephalogram	3
Reassessing anhedonia in Genetic Absence Epilepsy: Sucrose preference unaltered by spike-wave discharges in WAG/Rij rats	3
Foramen ovale electrode investigation in the era of SEEG: Results and a reappraisal	3
Corrigendum to “Oxidative stress, metalloproteinase and LDH in children with intractable and non-intractable epilepsy as reflected in salivary analysis” [Epilepsy Res. 108 (1) (2014) 117–124]	3
Multimodal diagnostic concordance and seizure outcomes following stereo-encephalography-guided volumetric radiofrequency thermocoagulation in drug-resistant epilepsy	3
Corrigendum to “Long-term outcome and predictors of vagus nerve stimulation for drug-resistant epilepsy: Real-world evidence from the Korean National Hospital Consortium” [Epilepsy Res. 210 (2025) 107	3
The construct validity of perceived disability scale in people with epilepsy	3
GRIN2A-related epilepsy and speech disorders: A comprehensive overview with a focus on the role of precision therapeutics	3
Evaluation of seizure semiology, genetics, magnetic resonance imaging, and electroencephalogram findings in children with Rett syndrome: A multicenter retrospective study	3
Efficacy, tolerability and safety of perampanel in population with pharmacoresistant focal seizures: A systematic review and meta-analysis	3
Anti-seizure medication-induced developmental cell death in neonatal rats is unaltered by history of hypoxia	3
Expression and correlation of the NOD-like receptor family, pyrin domain-containing 3 inflammasome and the silent information regulator 1 in patients with drug-resistant epilepsy	3