OOIR: Observatory of International Research

Papers

(The TQCC of Endocrine Journal is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Reflections and expectations of an endocrinologist and diabetologist on the launch of a new, board-certified Endocrinology, Diabetes and Metabolism specialist system pioneered by the JES and the JDS	163
Characteristic external genitalia in male neonates with 5α-reductase deficiency	45
Once in a Lifetime~Dream, Passion, Challenge, and Respect for Peers~	36
Expression of SMADs in orthotopic human endometrium, ovarian endometriosis, and endometriotic lesions in a murine model	35
Mutual associations among responsiveness to differential diagnostic tests for Cushing’s disease, tumor size, and somatostatin receptor 5 expression in corticotroph tumors	29
Relationship between diabetes diet-related quality of life and dietary fiber intake among people with type 2 diabetes: a cross-sectional study	28
Arterial stiffness, high fasting glucose, and fatty liver as risk factors for visceral obesity in middle-aged Chinese individuals: a cross-sectional study	22
A 40-year challenge to resolve clinical questions through experimental/laboratory techniques	22
Teprotumumab-associated persistent unilateral hearing loss in dysthyroid optic neuropathy: a case report with review of the literature	21
Inhibition of mmu_circ_0009303 improves metabolic dysfunction-associated steatotic liver disease by regulating lipid metabolism and oxidative stress	21
The effect of arteriosclerosis on new-onset renal damage in diabetic patients	21
Early postoperative levothyroxine initiation after total thyroidectomy for Graves’ disease	20
The frequency of mutations in advanced thyroid cancer in Japan: a single-center study	20
Current status of the thyroid hormone measurement items in patients receiving levothyroxine monotherapy by the management based on the thyroid tissue volume	19
Prediction of fetal Graves’ disease among pregnant women with Graves’ disease who have undergone thyroidectomy or radioactive iodine therapy: A retrospective observational study	18
Proposed carbohydrate antigen 19-9 (CA19-9) cut-off values for the detection of pancreatic cancer in patients with poorly controlled diabetes: a real-world study	18
Safety management in Cushing syndrome during osilodrostat treatment based on morning blood cortisol level	17
Association between non-high-density lipoprotein cholesterol and type 2 diabetes: a systematic review and meta-analysis of cohort studies	17
Efficacy of asfotase alfa in a patient with adult-onset hypophosphatasia without obvious bone lesions: a case report with review of literature	16
Memories of our research on the hypothalamo-hypophyseal system	15
Relationship between Ca<sup>2+</sup> and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells	15
Association between iodine intake and metabolic syndrome in euthyroid adult in an iodine-replete area: a nationwide population-based study	14
Extracellular vesicles secreted from mouse muscle cells improve delayed bone repair in diabetic mice	14
Thyrotropin-releasing hormone stimulates NR4A3 expression in the pituitary thyrotrophs of proestrus rats	14
Complete and sustained remission of hypercortisolism with pasireotide treatment of an adrenocorticotropic hormone (ACTH)-secreting thoracic neuroendocrine tumor: an n-of-1 trial	14

Secondary <i>vs.</i> primary pituitary xanthogranulomas: which yellow is more mellow?	14
Skeletal muscle integrin expression in non-obese men with varying degrees of insulin sensitivity	14
Distribution of blood pressure and its positive association with body mass index standard deviation score in pediatric patients with X-linked hypophosphatemia: a sub-group analysis from the SUNFLOWER	13
Impact of the transition from radioimmunoassay (RIA) to chemiluminescent enzyme immunoassay (CLEIA) for the measurement of plasma aldosterone concentration (PAC) on the diagnosis of primary aldosteron	13
Risk factors of neonatal hypoglycemia in neonates born to mothers with gestational diabetes	12
Anti-aging effects of the adrenal androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate: mechanisms of action and beneficial effects in older people	12
Osilodrostat treatment in patients with Cushing’s disease of Asian or non-Asian origin: a pooled analysis of two Phase III randomized trials (LINC 3 and LINC 4)	12
Establishment of a prognostic score for distant recurrence in follicular thyroid carcinoma	12
The role of bile acids in regulating glucose and lipid metabolism	12
Therapeutic effect of selective interleukin-2-inducible tyrosine kinase inhibitor in orbital fibroblasts from patients with Graves’ orbitopathy	11
Selectively bred rodent models for studying the etiology of type 2 diabetes: Goto-Kakizaki rats and Oikawa-Nagao mice	11
Association between the intake of plant and animal proteins and the serum fibroblast growth factor-23 level in patients with chronic kidney disease analyzed by the isocaloric substitution model	11
GPR75 signaling is dispensable for reproduction but contributes to feeding and body growth in rats on normal chow and is involved in high-fat diet-induced hyperphagia, obesity, and hyperglycemia devel	11
Recent progress in pathophysiology of cortisol-producing adrenal tumor	11
Nationwide survey on iodine nutritional status and thyroid function in Japanese adults	11
Multidisciplinary approach to management of osteoporosis with osteoporosis liaison service (OLS)	11
Recurrent distal cholangiocarcinoma and humoral hypercalcemia of malignancy: report of a rare case and literature review	10
How to discontinue potassium iodide in combined therapy with methimazole for initial treatment of Graves’ disease	10
Sodium-glucose cotransporter-2 inhibitors increase urinary tract infections?—a cross sectional analysis of a nationwide Japanese claims database	9
Adjuvant treatments for locally advanced differentiated thyroid cancer: a nationwide survey in Japan	9
Clinical and molecular analyses of isolated central congenital hypothyroidism based on a survey conducted in Japan	9
Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases	9
A more accurate relationship between serum androgen and metabolism among healthy, nonobese, reproductive-age women based on liquid chromatography-tandem mass spectrometry	9
A nomogram based on ultrasound characteristics to predict large-number cervical lymph node metastasis in papillary thyroid carcinoma	9
Physiology and clinical applications of GIP	9
Associations of phase angle obtained by bioelectrical impedance analysis with muscle mass and strength in Japanese patients with type 2 diabetes	9
A novel frameshift variant of <i>GATA3</i> (p.Ala17ProfsTer178) responsible for HDR syndrome in a Japanese family	9
Long-term outcomes and prognostic factors of patients with lung metastases from differentiated thyroid cancer after radioiodine therapy in Japan	9
Altered expression of autophagy-related molecules and β-catenin in different subtypes of thyroid cancer: co-localization in intranuclear cytoplasmic inclusions	9
Low-affinity IgG-mediated macro-TSH: diagnostic limitations of peak-based gel filtration chromatography—a case report with review of literature	8
Association of physical activity and sedentary time with risk of non-alcoholic fatty liver disease in adults with and without diabetes mellitus	8
In celebration of 100 exciting years of the Japan Endocrine Society	8
Iliopsoas muscle to visceral fat ratio on CT predicts Cushing’s syndrome in elderly females with adrenal tumors	8
Early diagnosis of capivasertib-associated severe hyperglycemia with diabetic ketosis diagnosed in routine clinical practice: a case report with review of literature	8
A comprehensive analysis of clinical factors interacting with ectopic intrathyroidal thymus in children and adolescents: The Fukushima Health Management Survey	8
Hyperandrogenism caused by a rare adrenocortical oncocytic neoplasm with uncertain malignant potential: a case report and review of the literature	8
Metachronous multiple insulinomas in oculo-facio-cardio-dental syndrome harboring a novel <i>BCOR</i> deletion: a case report with review of literature	7
Epithelial mesenchymal transition in human menstruation and implantation	7
Chronic hyperadiponectinemia induced by transgenic overexpression increases plasma exosomes without significantly improving glucose and lipid metabolism	7
Characterization of individuals in whom body weight loss precedes diabetes onset: a retrospective, observational, longitudinal cohort study based on health checkup in Japan	7
Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study	7
Survey of glucocorticoid dose escalation in patients with adrenal insufficiency during the peri-COVID-19 vaccination period	7
A questionnaire-based survey of medical conditions in adults with Prader-Willi syndrome in Japan: implications for transitional care	7
Efficacy and safety of once-weekly somatrogon following up to 4 years of treatment in Japanese children with growth hormone deficiency: results from an open-label extension of a phase 3 study	7
Polycystic ovary syndrome in a patient with type B insulin resistance syndrome can improve with glucocorticoid treatment: a case report and literature review	7
Esaxerenone improves the blood pressure and metabolic parameters of hypertensive subjects with diabetes	7
Single bolus injection of nicotinamide mono nucleotide increases systemic insulin sensitivity in association with activation of NAD salvage pathway in the liver and adipose tissue in mice	7
Hyponatremia due to preserved non-osmotic arginine vasopressin secretion in adipsic diabetes insipidus: a case report with review of literature	7
The association of thyroid parameters with markers of chronic kidney disease in euthyroid patients with type 2 diabetes	7
Sleep-related factors and circulating levels of sex hormones in premenopausal Japanese women	7

The prognosis of severe subclinical hyperthyroidism with TSH below 0.1 μU/mL due to Graves’ disease in the Japanese population	7
Improvement in body composition of Japanese participants with Prader-Willi syndrome following somatropin treatment: an open-label, multi cohort Phase 3 study	7
An adrenal incidentaloma that had appeared to produce dehydroepiandrosterone-sulfate in excess before immunohistochemical study of the tumor	7
The oral disposition index calculated from a meal tolerance test is a crucial indicator for evaluating differential normalization of postprandial glucose and triglyceride excursions in morbidly obese	7
An essential reference to be incorporated in the article: Inhibitory effects of estetrol on the invasion and migration of immortalized human endometrial stromal cells	7
Impacts of the use of chemiluminescent enzyme immunoassay-measured plasma aldosterone concentration in the diagnostic process of unilateral primary aldosteronism: a real-world multicenter study in Jap	6
A real-world disproportionality analysis of tirzepatide-related adverse events based on the FDA Adverse Event Reporting System (FAERS) database	6
The effect of acromegaly on thyroid disease	6
Biological roles of growth hormone/prolactin from an evolutionary perspective	6
Bowel perforation associated with Cushing’s disease: a case report with literature review	6
From cross-section to prognosis: risk factors for renal function deterioration in primary hyperparathyroidism	6
Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity	6
A case of vasoactive intestinal peptide-secreting tumor (VIPoma) arising from <i>MEN1</i> inactivation which recurred 15 years after the initial resection	6
Assessment of body fat mass, anthropometric measurement and cardiometabolic risk in children and adolescents with achondroplasia and hypochondroplasia	6
Prediction of insulin resistance using multiple adaptive regression spline in Chinese women	6
Association between serum testosterone changes and parameters of the metabolic syndrome	6
Mineralocorticoids induce polyuria by reducing apical aquaporin-2 expression of the kidney in partial vasopressin deficiency	6
46,XY 17 alpha-hydroxylase/17,20 lyase deficiency with breast development: A case report and literature review	5
Physiological and pathophysiological actions of insulin in the liver	5
Nighttime hypoglycemia in Japanese children with type 1 diabetes mellitus treated with multiple daily injection insulin therapy	5
Encapsulated human islets in alginate fiber maintain long-term functionality	5
Cardiovascular complications in insulin resistance and endocrine diseases	5
Potentially fatal crisis after <sup>177</sup>Lu-DOTATATE therapy for paraganglioma: a case report with review of literature	5
Prediction-based prompt levothyroxine replacement to prevent a hypothyroid state after immune-related adverse events involving the thyroid gland	5
The relationship between different metabolic phenotypes and bone indices in Chinese children and adolescents aged 12–18 years old	5
Food-dependent Cushing’s syndrome due to unilateral adrenocortical adenoma with cortisol secretion without ACTH elevation detected in peripheral blood by the CRH test: a case report	5
Association of mobile phone usage time with incidence of diabetic retinopathy in type 2 diabetes: a prospective cohort study	5
Disseminated intravascular coagulation as a frequent and critical complication of thyroid storm: a single-center retrospective survey	5
The genetic alterations of rectal neuroendocrine tumor and indications for therapy and prognosis: a systematic review	5
Adrenocortical carcinoma with circulating tumor DNA analysis at post-operative recurrence: a case report with review of literature	5
Impact of coronavirus disease 2019 in seasonal variation of hemoglobin A1c in adults with type 1 diabetes and the effect of the mode of treatment: a single-center retrospective study for 2019 and 2021	5
Scutellarin mitigates high glucose-induced pyroptosis in diabetic atherosclerosis: Role of Nrf2-FBXL2-mediated NLRP3 degradation	5
Incidence of the postpartum diagnosis of thyroid eye disease in relation to thyroid function in Graves’ disease	5
Associations between a polygenic risk score and the risk of gestational diabetes mellitus in a Chinese population: a case-control study	5
Short- and long-term prognostic analysis of supraclavicular oblique incision <i>versus</i> traditional low-collar incision in thyroidectomy	4
Imbalances in adrenal hormones and their effects on bone metabolism	4
Interleukin-17 prevents oxidative stress from damaging osteoblast formation by inhibiting autophagic degradation of metallothionein-2	4
Safety, pharmacokinetics, and potential benefits of TSH-receptor-specific monoclonal autoantibody K1-70<sup>TM</sup> in Japanese Graves’ disease patients: results of a phase 1 trial	4
Unintentional discontinuation of topical corticosteroids after emergency hospitalization can exacerbate adrenal insufficiency	4
FGF23-related hypophosphatemia in a patient with small cell lung cancer: a case report and literature review	4
Neurological consequences of adult-onset hypothyroidism	4
The clinical significance of <i>SIGLEC1</i> mRNA levels derived from peripheral leukocytes in autoimmune thyroid diseases and type 1 diabetes	4
Lipopolysaccharide inhibits osteoblast formation and receptor activator of nuclear factor-κB ligand degradation <i>via</i> autophagy inhibition	4
Soluble tumor necrosis factor receptors in diabetes: risk sensing and receptor-resolved targeting	4
Effects of laparoscopic sleeve gastrectomy on nonalcoholic fatty liver disease and TGF-β signaling pathway	4
The impact of testosterone in men’s health	4
Development of a prediction model by combining tumor diameter and clinical parameters of adrenal incidentaloma	4
Long-term effectiveness and safety of daily growth hormone therapy in Japanese children with Noonan syndrome: a post-marketing surveillance study	4
Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity	4
Classification of pseudohypoaldosteronism type II as type IV renal tubular acidosis: results of a literature review	4
Primary aldosteronism patients with previous cardiovascular and cerebrovascular events have high aldosterone responsiveness to ACTH stimulation	4
Genetic screening of the insulin-like growth factor 1 receptor gene in children born small for gestational age: the continuing importance of insulin-like growth factor 1 signaling	4
Advancing liver metabolic zonation with single-cell and spatial omics	4
Proposed reference intervals of serum insulin-like growth factor-1 (IGF-1) levels in older Japanese populations	4
Children with idiopathic short stature and growth hormone deficiency exhibit similar changes in gut microbiota	4
Clinicopathological and molecular characteristics of papillary thyroid carcinoma in adolescent and young adult patients	4
Erratum	4
Impact of autonomous cortisol secretion on adrenal venous sampling with and without ACTH stimulation in patients with primary aldosteronism	4
Brown fat thermogenesis and branched-chain amino acids in metabolic disease	4
Dose-response relationship between the fatty liver index and asthma risk: NHANES 2001~2018	4
Outcomes of immediate surgery for low-risk papillary thyroid microcarcinoma in patients with or without risky features at surgery	4
Celebrating 100<sup>th</sup> Anniversary of the Japan Endocrine Society	4
Knockdown of Gfi1 increases BMSCs exosomal <i>miR-150-3p</i> to inhibit osteoblast ferroptosis in steroid-induced osteonecrosis of the femoral head through BTRC/Nrf2 axis	4
Congratulations on the 100<sup>th</sup> anniversary of the Japan Endocrine Society	4
The role of KNDy neurons in human reproductive health	4
Parathyroid carcinoma: impact of preoperative diagnosis on the choice of surgical procedure	4
In Memoriam: Professor Tadashi Inagami	4
The soliloquy of a clinical endocrinologist who spent half a century as an academic member	4
The influence of hypertensive disorders of pregnancy on the development of long-term postpartum type 2 diabetes mellitus	4
Association of HLA-DRB1 pocket structures with susceptibility and prognosis of Graves’ and Hashimoto’s disease	4