Biological & Pharmaceutical Bulletin

Article	Citations
Changes in Pharmacy Students’ Awareness of Hepatitis B Patients through Patient Lectures as Humanity Education: Findings from Questionnaire Surveys of Face-to-Face and Simultaneous Remote Classes	47
Errata for Biological and Pharmaceutical Bulletin	39
Effects of Disodium Cromoglycate Treatment in the Early Stage of Diabetic Nephropathy: Focus on Collagen Deposition	32
Genipin Attenuates Sepsis-Induced Splenocyte Apoptosis <i>via</i> the Inhibition of Endoplasmic Reticulum Stress	30
Characterization of Potentially Inappropriate Medications That Need Special Attention in the Elderly with Dementia by Analyzing Pharmacy Claims Data	29
Protective Effect of Pemafibrate Treatment against Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats	28
Dietary Zinc Deficiency Induces Ca<sub>v</sub>3.2-Dependent Nociceptive Hypersensitivity in Mice	27
Effect of Chronic Ethanol Consumption on Exogenous Glucose Metabolism in Rats Using [1-<sup>13</sup>C], [2-<sup>13</sup>C], and [3-<sup>13</sup>C]glucose Breath Tes	26
Association between Weight Gain and Sex-Related Differences through 5-Fluorouracil Administration	24
Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine	24
Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database	24
Target Therapeutic Ranges of Anti-MRSA Drugs, Linezolid, Tedizolid and Daptomycin, and the Necessity of TDM	22
Cross-Cancer Type Evaluation of Potential Interstitial Lung Disease Complications of Immune Checkpoint Inhibitors Using JADER	21
Development of a Specific Competitive ELISA for Plasma Adropin Levels and Its Application to Investigating Energy Homeostasis in Mice	20
Comparison of Addition of Indications for Antineoplastic Agents Approved in the United States and Japan from 2001 to 2020	18
Development of an Analytical Method for Unsaturated Disaccharides from Heparan Sulfate Using Dansylhydrazine Derivatization and High-Performance Liquid Chromatography with Fluorescence Detection	17
Identification and Physiological Analysis of Novel Riboflavin Transporter RFVT	17
Pharmacological Characteristics of Extracellular Ca<sup>2+</sup> Influx Pathways Responsible for Platelet-Activating Factor-Induced Contractions in Rat Esophagus Smooth Muscle: Involvement	17
Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport	17
New Directions for Advanced Targeting Strategies of EGFR Signaling in Cancer	16
Chlorogenic Acid Inhibited Epithelial–Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy	16
Sorghum (<i>Sorghum bicolor</i>) Extract-Induced Adipogenesis Is Independent of PPARγ Ser273 Phosphorylation in 3T3-L1 Adipocytes	15
Russelioside A, a Pregnane Glycoside from <i>Caralluma tuberculate</i>, Inhibits Cell-Intrinsic NF-κB Activity and Metastatic Ability of Breast Cancer Cells	15
Shimanami Leaf Intake Affects Bowel Movement and Intestinal Microbiota in Mice	14
Effect of Celecoxib Administration on the Skin of 40-Week-Old Mice	14

Selective Inhibitory Effect of Hesperetin on the Automaticity of the Guinea Pig Pulmonary Vein Myocardium	14
Impact of Drugs and Patient Characteristics on Life Expectancy during the Induction Phase of Dialysis	14
Vitamin K3 Suppresses Pyroptosis in THP-1 Cells through Inhibition of NF-κB and JNK Signaling Pathways	14
Process Optimization of Charge-Reversible Lipid Nanoparticles for Cytosolic Protein Delivery Using the Design-of-Experiment Approach	14
A Novel Function of Sphingosylphosphorylcholine on the Inhibitory Effects of Acetylcholinesterase Activity	14
Usefulness of an Intermittently Scanned Continuous Glucose Monitoring System for Risk Management of Individuals without Diabetes in Japan	13
LncRNA <i>Gm16638-201</i> Inhibits the 14-3-3Ɛ Pathway in the Murine Prefrontal Cortex to Induce Depressive Behaviors	13
RasGRP2 Attenuates TAGE Modification of eNOS in Vascular Endothelial Cells	13
Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression	13
Fosphenytoin Alleviates Herpes Simplex Virus Infection-Induced Provoked and Spontaneous Pain-Like Behaviors in Mice	13
Population Pharmacokinetic Model of Amiodarone and <i>N</i>-Desethylamiodarone Focusing on Glucocorticoid and Inflammation	13
Pharmacological Investigation of Hypoalbuminemia on the Prolonged and Potentiated Action of Midazolam in Rats	13
A Reactive Metabolite of Clozapine Induces Hematopoietic Toxicity in HL-60 Cells Undergoing Granulocytic Differentiation through Its Effect on Glutathione Metabolism	13
Clozapine Induces Neuronal Activation in the Medial Prefrontal Cortex in a Projection Target-Biased Manner	12
3′,4′-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT–mTOR and NF-κB Pathways	12
Cascade Enzyme Catalysis Supported Starvation and Photodynamic Synergistic Therapy for Breast Cancer	12
Subsidy Programs for Herpes Zoster Vaccination in Japanese Municipalities	12
The Role of SGLT2 Inhibitor Ipragliflozin on Cardiac Hypertrophy and microRNA Expression Profiles in a Non-diabetic Rat Model of Cardiomyopathy	12
Amodiaquine Analogs Are Potent Inhibitors of Interleukin-6 Production Induced by Activation of Toll-Like Receptors Recognizing Pathogen Nucleic Acids	12
3-Nitropropionic Acid Enhances Ferroptotic Cell Death <i>via</i> NOX2-Mediated ROS Generation in STHdhQ111 Striatal Cells Carrying Mutant Huntingtin	12
Foreword	12
Magnitude of Fruit Juice–Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices	11
Kuanoniamine C Suppresses Adipogenesis and White Adipose Tissue Expansion by Modulating Mitochondrial Function	11
Inhibition Mechanism of SARS-CoV-2 Infection by a Cholesterol Derivative, Nat-20(S)-yne	11
Inhibition of p38 Mitogen-Activated Protein Kinases Attenuates Methylmercury Toxicity in SH-SY5Y Neuroblastoma Cells	11
Foreword	11
Piperacillin Exacerbates Vancomycin-Induced Toxicity in Renal Proximal Tubular Cells	11
Prospective Analysis of Factors Influencing Inter-Individual Variation in Trough Plasma Voriconazole Concentrations in Older Patients—Impact of High <i>α</i>1-Acid Glycoprotein Levels	11
Lipopolysaccharide Priming Exacerbates Anaphylatoxin C5a-Induced Anaphylaxis in Mice	11
Indomethacin, a Non-steroidal Anti-inflammatory Drug, Induces Skin Dryness <i>via</i> PPARγ in Mice	11
Evaluation of the Potential Inhibitory Effects of Medications for Detrusor Overactivity on Platelet-Activating Factor (PAF)-Induced Mechanical Activity in Guinea Pig Bladder Smooth Muscle	11
Structural Perspective of the Double-Stranded RNA Transport Mechanism by SID-1 Family Proteins	11
Lymphatic Transport and Immune Activation Effect by Locally Administered Extracellular Vesicles from <i>Saccharomyces cerevisiae</i> as Biocompatible Vaccine Adjuvants	11
Variation in Expression of Cytochrome P450 3A Isoforms and Toxicological Effects: Endo- and Exogenous Substances as Regulatory Factors and Substrates	11
Innovative System for Delivering Nucleic Acids/Genes Based on Controlled Intracellular Trafficking as Well as Controlled Biodistribution for Nanomedicines	10
Chronotropic and Inotropic Effects of Sudachitin, a Polymethoxyflavone from the Peel of <i>Citrus sudachi</i> on Isolated Rat Atria and Its Underlying Mechanisms	10
Intracerebroventricular Administration of Dermorphin-Dynorphin Analogs Producing Antidepressant-Like Effects through Activation of μ<sub>1</sub>- and κ-Opioid Receptors in Mice	10
L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α<sub>1B</sub> Receptor at the Second Transmembrane Interface	10
Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels <i>via</i> VEGF Signaling Pathway Activation by miRNA-126	10
Antidepressant Effect of Intracerebroventricularly Administered Deltorphin Analogs in the Mouse Tail Suspension Test	10
Effect of a Single Dose of Oxaliplatin on the Induction of Peripheral Neuropathy in a Rat Model: An <i>in Vivo</i> Electrophysiological Study	10
Cryopreservation of Hepatocyte Organoid-Derived Cells Generated from Human iPS Cells	10
Dose Individualization of Oral Multi-Kinase Inhibitors for the Implementation of Therapeutic Drug Monitoring	10
Foreword	9
Clinical Analysis and <i>in Vitro</i> Correlation of BCRP-Mediated Drug–Drug Interaction in the Gastrointestinal Tract	9
Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells	9
Platelets Affect the Activity of Amino Acid Transporter SNAT4 in HuH-7 Human Hepatoma Cells	9
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy	9
Antidepressant-Like Effects of Intracerebroventricular Injection of Nociceptin Analogs in Mice	9
Exploring Cell-Penetrating Peptides as Penetration Enhancers in Eye Drop Formulations Using a Reconstructed Human Corneal Epithelial Model	9

Cloperastine Reduces IL-6 Expression <i>via</i> Akt/GSK3/Nrf2 Signaling in Monocytes/Macrophages and Ameliorates Symptoms in a Mouse Sepsis Model Induced by Lipopolysaccharide	9
Carbon Monoxide Alleviates Post-ischemia–reperfusion Skeletal Muscle Injury and Systemic Inflammation	9
Effects of Antibacterial Agents on Cancerous Cell Proliferation	9
Protective Effects of <i>Pleurotus</i> Species on UVB-Induced Skin Disorders at Clinically Relevant Plasma Concentrations of the Antioxidant Ergothioneine in Hairless Mice	9
ELK3 Targeting AEG1 Promotes Migration and Invasion of Ovarian Cancer Cells under Hypoxia	9
Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy	9
Substrate-Dependent Alteration in the <i>C</i>- and <i>O</i>-Prenylation Specificities of <i>Cannabis</i> Prenyltransferase	9
Siweixizangmaoru Decoction Ameliorated Type II Collagen-Induced Arthritis in Rats <i>via</i> Regulating JAK2–STAT3 and NF-κB Signaling Pathway	8
Influence of the Th1 Cytokine Environment on CCL5 Production from Langerhans Cells	8
Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects	8
Panobinostat, a Histone Deacetylase Inhibitor, Reduces LPS-Induced Expression of Inducible Nitric Oxide Synthase in Rat Immortalized Microglia HAPI Cells	8
RasGRP2 Attenuates Oxygen Deprivation-Induced Autophagy in Vascular Endothelial Cells	8
Inhibition Effect of <i>Eucommia ulmoides</i> Leaf Extract on Interleukin 8 Production by A549 Cells	8
Impact of Polypharmacy and Risk Factors for Exacerbation of Lower Urinary Tract Symptoms in Patients with Urological Conditions: A Retrospective Study in a Japanese Municipal Hospital	8
Self-controlled Case Series Study for Acute Kidney Injury after Starting Proton Pump Inhibitors or Potassium-Competitive Acid Blocker in Patients with Cancer Using a Large Claims Database	8
Characterization of CNS Network Changes in Two Rodent Models of Chronic Pain	8
Evaluation of Transport Activity Using Mouse Jejunal Epithelial Cell Monolayer Culture System	8
Phosphatidylcholine-Plasmalogen-Oleic Acid Has Protective Effects against Arachidonic Acid-Induced Cytotoxicity	8
Saikosaponin A Inhibits Growth of Human Bladder Carcinoma T24 and 5637 Cells Both <i>in Vitro</i> and <i>in Vivo</i>	8
Impact of Cilostazol Pharmacokinetics on the Development of Cardiovascular Side Effects in Patients with Cerebral Infarction	8
Analysis of Risk Factors for Developing Tuberculosis in Patients Who Received Prophylactic Latent Tuberculosis Infection Treatment with Experience of Biologic Medications	8
Effective Location of the Plantar Surface of the Hind Paw for the Evaluation of Mechanical Hyperalgesia Using von Frey Filaments in Mice Treated with Paclitaxel	8
Infliximab Treatment Persistence among Japanese Patients with Chronic Inflammatory Diseases: A Retrospective Japanese Claims Data Study	8
Anacardic Acid Derivatives Isolated from Fungal Species <i>Tyromyces fissilis</i> as New Histone Acetyltransferase Inhibitors	8
A Novel Cross-Immune Antigen Vaccine Platform for Influenza Virus Type A	8
Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin	8
Seasonal Variations in Drug-Related Erythema Multiforme: A Time Series Analysis Using the JADER Database	8
Ononin Relieves the Thyroid Cancer Progression through Targeting the Caspase 3 and CD274 Expression Levels	8
Ginsenosides in <i>Panax ginseng</i> Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation	8
The Cyclin-Dependent Kinase 4/6 Inhibitor Abemaciclib Is Tolerated Better than Palbociclib by Advanced Breast Cancer Patients with High Serum Albumin Levels	8
Influence of Size, Flexibility, Hydrophobicity, Surface Charge, and Surface Chemistry on the Biodistribution of Orally Administered Polymer Nanoparticles	8
Association between Early Guanfacine Discontinuation and Somnolence for Attention-Deficit/Hyperactivity Disorder	8
Extracellular Vesicles Derived from the Serum of <i>Seriola quinqueradiata</i> Induce Human Umbilical Vein Endothelial Cell Proliferation through Angiogenic Signaling	8
Methylselenocysteine Potentiates Etoposide-Induced Cytotoxicity by Enhancing Gap Junction Activity	8
Effect of Orally Ingested Water Containing H<sub>2</sub>-Filled Ultrafine Bubbles (UFBs) on Ethanol-Induced Oxidative Stress in Rats	7
Endogenous SOLOIST/MRTFB i4, a Neuronal Isoform of MKL2/MRTFB, Positively and Negatively Regulates SRF Target Immediate Early Genes in Neuro-2a Cells	7
Possible Therapeutic Applications of Targeting STAP Proteins in Cancer	7
Functional Analysis of Modified Caco-2 Cells Carrying CES2A1 as a Model for Intestinal Absorption of Prodrugs	7
Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats	7
Risk Factors for Treatment Transition in Patients with Low-Risk Atrial Fibrillation Patients Undergoing Anticoagulation Monotherapy: A Large Claims Database Study in Japan	7
Emedastine Inhibits Th1 and Th2 Cell Differentiation Mediated by Mast Cells	7
Andrographolide/Phospholipid/Cyclodextrin Complex-Loaded Nanoemulsion: Preparation, Optimization, <i>in Vitro</i> and <i>in Vivo</i> Evaluation	7
Mogroside Alleviates Diabetes Mellitus and Modulates Intestinal Microflora in Type 2 Diabetic Mice	7
Ketogenic Diet Alleviates Mechanical Allodynia in the Models of Inflammatory and Neuropathic Pain in Male Mice	7
Contamination-Free Milling of Ketoprofen Nanoparticles Using Mannitol Medium and Hoover Automatic Muller: Optimization of Effective Design of Experiment	7
Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment	7
Curcumin Is Primarily Distributed in Lung, Spleen and Liver, Metabolized to Glucuronide and Sulfate, and Excreted through Bile and Urine by Using an Amorphous Curcumin Formulation with High Absorbabil	7
Qualitative Changes in Collagen Induced by UV Irradiation Affect Its Interaction with Cells	7
Foreword	7
Point Mutation Analysis of the Drug Efflux Pump MexB in Clinical Isolates of <i>Pseudomonas aeruginosa</i>	7
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte	7
The Potential Effects of 2,3,4-Trihydroxybenzophenone on the Transient Cerebral Ischemic Stroke in Male Mice	7
Pivotal Role of Signal-Transducing Adaptor Protein-2 in Pathogenesis of Autoimmune Hepatitis	7
Skin Dryness Induced in the KK-Ay/TaJcl Type 2 Diabetes Mouse Model Deteriorates Following Dapagliflozin Administration	6
Longitudinal Trend in Antimicrobial Susceptibility among <i>Haemophilus influenzae</i>: A Single-Centre Study in Japan	6
Blocking CXC Motif Chemokine Ligand 2 Ameliorates Diabetic Peripheral Neuropathy <i>via</i> Inhibiting Apoptosis and NLRP3 Inflammasome Activation	6
Analysis of Risk Factors for Infusion-Related Reactions Following Rituximab Administration in Patients with Desensitization before Renal Transplantation	6
Structural Impact Assessment of Cytochrome P450 2A13 Polymorphisms Using Molecular Dynamics Simulations	6
Effects of Ingested Water Volume on Oral Absorption of Fenofibrate, a BCS Class II Drug, from Micronized and Amorphous Solid Dispersion Formulations in Rats	6
<i>Salvia miltiorrhiza</i> Prevents Methylglyoxal-Induced Glucotoxicity <i>via</i> the Regulation of Apoptosis-Related Pathways and the Glyoxalase System in Human Umbilical Vei	6
Serum Concentrations of Infliximab and IL-6 for Predicting One-Year Discontinuation of Infliximab Treatment Owing to Secondary Non-response in Patients with Rheumatoid Arthritis	6
Phospholipid Scramblase 1 Localizes Proximal to Sphingomyelin Synthase Isoforms but Is Not Involved in Sphingomyelin Synthesis	6
Protective Effects of <i>Coptis chinensis</i> Rhizome Extract and Its Constituents (Berberine, Coptisine, and Palmatine) against α-Synuclein Neurotoxicity in Dopaminergic SH-SY5Y Cells	6
Probes with Tailored Pharmacokinetics for Radiotheranostics	6
Medical Economic Benefit Derived from the Use of Tracing Reports by Pharmacy-Based Pharmacists for Pharmaceutical Intervention and Reduction of Leftover Medicines	6
Development of a Nanocarrier-Based Splenic B Cell-Targeting System for Loading Antigens <i>in Vitro</i>	6
Assessment of Risk of Acidosis in Patients with Mild-to-Moderate Chronic Kidney Disease Treated with Intravenous Branched-Chain Amino Acid-Enriched Solution: A Propensity Score Matching Analysis	6
Mechanism of Human Cytomegalovirus-Induced Epithelial–Mesenchymal Transition in Glioma Cells <i>via</i> the Upregulation of RIP2 Expression	6
<i>Ajania purpurea</i> Extract Attenuates LPS-Induced Inflammation in RAW264.7 Cells and Peritonitis Mice	6
Ciclesonide Inhibits SARS-CoV-2 Papain-Like Protease <i>in Vitro</i>	6
Evaluation of Puberulic Acid-Induced Nephrotoxicity Using 3D-RPTEC	6
Goji Berry Juice Prevents Tumor Necrosis Factor Alpha-Induced Xerostomia in Human Salivary Gland Cells	6
Fabrication of 3D-Printed Contact Lens Composed of Polyethylene Glycol Diacrylate for Controlled Release of Azithromycin	6
Identification of the RORα Transcriptional Network Contributes to the Search for Therapeutic Targets in Atherosclerosis	6
The Mechanism of 5-Fluorouracil-Induced Hyperpigmentation in HRM-2 Hairless Mice: Focus on the Increase of Blood Vessels	6
Octa-arginine and Octa-lysine Promote Cell Adhesion through Heparan Sulfate Proteoglycans and Integrins	6
New Drug Delivery Systems for Stable Oral Absorption: Theory, Strategies, and Applications	6
Risk Assessment for Heart Failure in Patients with Type 2 Diabetes Mellitus Treated with Dipeptidyl Peptidase 4 Inhibitor Using a Large Claims Dataset	6
Machine Learning-Based Model for Estimating Vancomycin Maintenance Dose to Target the Area under the Concentration Curve of 400–600 mg·h/L in Japanese Patients	6
Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy	6

Anticancer Effects of New Disulfiram Analogs	6
Ameliorative Effects of Sweeteners on a Mouse Jet Lag Model	6
Foreword	6
Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain	6
Removal of Soluble ACE2 in VeroE6 Cells by 17β-Estradiol Reduces SARS-CoV-2 Infectivity	6
Impact of Bridged Nucleic Acid Positions within Blocking Oligonucleotides on DNA Amplification Inhibition in Wild-Type Blocking PCR	6
Development of SCAR Markers to Identify Medicinal Cultivars of <i>Paeonia lactiflora</i>	6
Inhibitory Actions of Antidepressants, Hypnotics, and Anxiolytics on Recombinant Human Acetylcholinesterase Activity	6
Effects of Body Composition on Renal Function Estimates in Older Patients	6
Biochemical Characterizations of the Putative Amidase Endolysin Ecd18980 Catalytic Domain from <i>Clostridioides difficile</i>	6
BET Inhibitors Induce p53-Independent Growth Arrest in HCT116 Cells <i>via</i> Epigenetic Control of the E2F1/c-<i>MYC</i> Axis	5
Polyphyllin E Inhibits Proliferation, Migration and Invasion of Ovarian Cancer Cells by Down-Regulating the AKT/NF-κB Pathway	5
Characterization of Novel Cell-Adhesive Peptides for Biomaterial Development	5
Royal Jelly Maintains Epidermal Stem Cell Properties by Repressing Senescence	5
Induction of Melanin Synthesis by <i>Pueraria lobata</i> Leaves in B16 Murine Melanoma Cells and Three-Dimensional Human Skin Equivalent	5
Exploring IDI2-AS1, OIP5-AS1, and LITATS1: Changes in Long Non-coding RNAs Induced by the Poly I:C Stimulation	5
SRF and SRF Cofactor mRNA Expression Is Differentially Regulated by BDNF Stimulation in Cortical Neurons	5
Oligodendroglia Generate Vascular Mural Cells and Neurons in the Adult Mouse Brain	5
Liver and Plasma Concentrations of Food Chemicals after Virtual Oral Doses Extrapolated Using <i>in Silico</i> Estimated Input Pharmacokinetic Parameters to Confirm Reported Liver Toxicity	5
<i>Cry2</i> Alleviates Cisplatin-Induced Cytotoxicity in Mouse Renal Cortex Tubular Cell Lines	5
Rapid Screening Detection of Genetically Modified Papaya by Loop-Mediated Isothermal Amplification	5
Notice of Addendum for Biological and Pharmaceutical Bulletin	5
Calculation of Human Melatonin Partial Metabolic Clearance in Healthy Adult Volunteers for Investigation of a Novel <i>in Vivo</i> CYP1A2 Phenotyping Method: A Pilot Study	5
Proton Pumping ATPases: Rotational Catalysis, Physiological Roles in Oral Pathogenic Bacteria, and Inhibitors	5
Efficacy of Naldemedine on Intestinal Hypomotility and Adhesions in Rodent Models of Postoperative Ileus	5
Feasibility Study of Dendrimer-Based TTR-CRISPR pDNA Polyplex for Ocular Amyloidosis <i>in Vitro</i>	5
Expression of the Discoidin Domain Receptor Family Depended on Glucose and Their High Expression in Arterial Tissues in the Rat Model of Type 2 Diabetes	5
Prevention of Renal Interstitial Fibrosis by Suplatast in a Mouse Model	5
Functional Domain Mapping of Werner Interacting Protein 1 (WRNIP1)	5
A Complex of Type I Platelet-Activating Factor Acetylhydrolase (PAF-AH) Catalytic Subunits Switches from α1/α2 Heterodimer to α2/α2 Homodimer during Adipocyte Differentiation of 3T3-L1 Cells	5
Solubilizing Effect of Caffeine on Precipitate of Risperidone Oral Solution and Tea Beverage	5
Effect of Growth Hormone Receptor Deficiency on Androgen-Associated Gene Expression of Hepatic Drug Metabolizing Enzymes and Drug Transporters in Pigs	5
Synergistic Effect of Baculovirus-Mediated Endostatin and Angiostatin Combined with Gemcitabine in Hepatocellular Carcinoma	5
Development of a Method of Liquid Chromatography Coupled with Tandem Mass Spectrometry for Simultaneous Determination of Linezolid and Tedizolid in Human Plasma	5
Possible Involvement of DNA Methylation and Protective Effect of Zebularine on Neuronal Cell Death after Glutamate Excitotoxity	5
<i>Astragalus</i> Polysaccharide Suppresses Cell Proliferation and Invasion by Up-Regulation of miR-195-5p in Non-small Cell Lung Cancer	5
Clinical Profiles of Japanese Patients with Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Collected by a Nationwide System from 2006 to 2023	5
Differential Suppressive Effects of Rho Kinase Inhibitor Fasudil on Serotonin- and Noradrenaline-Induced Contractions of Human Internal Thoracic Arteries and Saphenous Veins	5
Quetiapine Reverses the Behavior and Myelination in Alcohol-Exposed Gestational Diabetes Mellitus Offspring Mice <i>via</i> ERK1/2 Signaling	5
Comparison of the Speed of Enrollment for Clinical Trials Conducted by Japanese and Global Pharmaceutical Companies	5
The Role of TNF-α in the Pathogenesis of Temporomandibular Disorders	5
Multifactorial Alterations in Lacosamide Exposure in an Elderly Woman with Symptomatic Epilepsy and Tuberculous Pleurisy: A Case Report	5
Usefulness of the Albumin–Bilirubin Score in Determining the Initial Dose of Voriconazole for Patients with Liver Cirrhosis	5
Proteasome Inhibition Induces IRF1 Downstream Molecules Independently of JAK Activity in Cancers	5
Non-neuronal Cholinergic Muscarinic Acetylcholine Receptors in the Regulation of Immune Function	5
Development of a Novel Gastric Process Simulation Model: The Successful Assessment of Bioequivalence and Bioinequivalence of a Biopharmaceutics Classification System Class II Weak Acid Drug	5
Cathepsin G-Induced Cell Aggregation of Breast Cancer MCF-7 Decreases Doxorubicin Sensitivity in a Hypoxia-Inducible Factor-Independent Mechanism	5
Polyunsaturated Fatty Acid-Derived Lipid Mediators That Regulate Epithelial Homeostasis	5
Inhibition of TRPC4/5 Channel Is Effective in Protecting against Histamine-Induced Hyperpermeability by Blocking Ca<sup>2+</sup> Influx in Lung Microvascular Endothelial Cells	5
Biotransformation of Morphinone and Its Glutathione Adduct Derived from Morphine by Anaerobic Gut Microbes in Guinea Pigs	5
New Maintenance Culture Method for Intestinal Stem Cells Derived from Human Induced Pluripotent Stem Cells	5
Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation	5
Qualification of <i>In Vitro</i> Dissolution Absorption System 2 (IDAS2) with Caco-2 and MDCK Cell Monolayers: Dose Sensitivity Study Using BCS Class I and III Drugs	5
A Survey of Near-Miss Dispensing Errors in Hospital Pharmacies in Japan: DEPP-J Study—Multi-Center Prospective Observational Study—	5
Modeled Rat Hepatic and Plasma Concentrations of Chemicals after Virtual Administrations Using Two Sets of <i>in Silico</i> Liver-to-Plasma Partition Coefficients	5
Anti-atrial Fibrillatory Effects of the TRPC3 Channel Inhibitor Pyrazole-3 in Rats with Atrial Enlargement Induced by Chronic Volume Overload	5
Impact of Gut Microbiota on the Pharmacokinetics of Glycyrrhizic Acid in Yokukansan, a Kampo Medicine	5
Mitochondrial Coenzyme Q<sub>10</sub> Delivery Improves Energy Production in Rat Cardiac Myoblasts and Duchenne Muscular Dystrophy Model Rat Cardiomyocytes	5
Gambogenic Acid Inhibits Basal Autophagy of Drug-Resistant Hepatoma Cells and Improves Its Sensitivity to Adriamycin	5
<i>MicroRNA-5572</i> Is Associated with Endoplasmic Reticulum Stress Responses in Low Zinc Treated and SOD1 G85R-Transfected HEK293 Cells	5
Association between Inhalation Instruction Method in Community Pharmacies and Inhaler Device Handling Error in Patients with Obstructive Lung Disease: An Evaluation of the Impact of Practical Demonstr	5
Construction of a Temperature-Sensitive Shuttle Vector between Lactic Acid Bacteria and <i>Escherichia coli</i> and Its Application to a Tn<i>10</i>-Based Random Mutagenesis To	5
Salidroside Induces Apoptosis in Human Gastric Cancer Cells <i>via</i> the Downregulation of ENO1/PKM2/GLUT1 Expression	5
PI3K/AKT1 Signaling Pathway Mediates Sinomenine-Induced Hepatocellular Carcinoma Cells Apoptosis: An <i>in Vitro</i> and <i>in Vivo</i> Study	5
Selexipag Improves Lipopolysaccharide-Induced ARDS on C57BL/6 Mice by Modulating the cAMP/PKA and cAMP/Epac1 Signaling Pathways	5
Topical Xerostomia Treatment with Hyaluronate Sheets Containing Pilocarpine	5
Renal Metabolomics Study and Critical Pathway Validation of Shenkang Injection in the Treatment of Chronic Renal Failure	5
Vitexin Attenuates Non-alcoholic Fatty Liver Disease Lipid Accumulation in High Fat-Diet Fed Mice by Activating Autophagy and Reducing Endoplasmic Reticulum Stress in Liver	5
Quantitative Assessment of the Post-translational Modifications of Human Serum Albumin by Dimethyl Trisulfide	5
Wogonin Attenuates Bleomycin-Induced Pulmonary Fibrosis and Oxidative Stress Injury <i>via</i> the MAPK Signaling Pathway	5
Decreased Analgesic Effect of Tramadol in Japanese Patients with CYP2D6 Intermediate Metabolizers after Orthopedic Surgery	5
Assessment of Diagnosis Timing of Attention-Deficit/Hyperactivity Disorder in Working-Age Workers with Psychiatric Diseases Using Large Claims Data	5
Combination Therapy with Betamethasone and Josamycin Demonstrates Superior Therapeutic Efficacy in an NC/Nga Mouse Model of Atopic Dermatitis	5
Curculigoside Represses the Proliferation and Metastasis of Osteosarcoma <i>via</i> the JAK/STAT and NF-κB Signaling Pathways	5
Calsequestrin-1 Deficiency Induced Malignant Hyperthermia-Like Skeletal Injury through Mitochondrial Disorder	5
Descriptive Study on a Nationwide Exploratory Questionnaire Survey of Emergency Contraceptive Pills and Their Sexual History and Knowledge in Japan	5
Transcriptional Mechanism of the Mouse β4-Galactosyltransferase 6 Gene in Mouse Neuroblastoma Cell Line Neuro-2a	5
A Novel Lithocholic Acid Derivative Upregulates Detoxification-Related Genes in Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids	5
Efficacy of Zinc Acetate in the Treatment of Zinc Deficiency in Elderly Inpatients and Effect of Total Dose on Its Replacement Therapy	5
LncRNA Snhg5 Attenuates Status Epilepticus Induced Inflammation through Regulating NF-κΒ Signaling Pathway	5
Current Status and Perspectives of Therapeutic Antibodies Targeting the Spike Protein S2 Subunit against SARS-CoV-2	5
Platelet-Activating Factor (PAF) Induces Strong Mechanical Activities Accompanied by Basal Tension Increases in Esophageal and Gastric Fundus Smooth Muscles from Rat	4
Identification of Azalamellarin N as a Pyroptosis Inhibitor	4
Development of a New Jelly Coating Technology (Oral Jelly Coating) to Improve Prescribed Medication Adherence	4
TNF-α Mediated the Disruption of Hepatic Tight Junction Expression in Blood–Biliary Barrier of Colitis <i>via</i> Downregulating PI3K/AKT Signaling Pathway	4
Revealing the Anticancer Mechanism of Cephaibol A, a Peptaibol Isolated from <i>Acremonium tubakii</i> BMC-58, Triggering Apoptosis <i>via</i> the Mitochondrial Pathway in Huma	4
Association between the Prognostic Nutritional Index and the Occurrence of Immune-Related Adverse Events	4
Different Properties of Involuted Thymus upon Nutritional Deficiency in Young and Aged Mice	4
Effects of Simvastatin on RBL-2H3 Cell Degranulation	4
Development of Low-Density Lipoprotein Receptor-Targeted Liposomes for Enhanced Accumulation in Ischemia/Reperfusion Environment	4
CRISPRa Analysis of Phosphoinositide Phosphatases Shows That TMEM55A Is a Positive Regulator of Autophagy	4
Regioselective Glucuronidation of Flavones at C5, C7, and C4′ Positions in Human Liver and Intestinal Microsomes: Comparison among Apigenin, Acacetin, and Genkwanin	4
Analysis of Appendicitis Cases in the Japanese Adverse Drug Event Report (JADER) Database	4
Binding of AraC-Type Activator DesR to the Promoter Region of <i>Vibrio vulnificus</i> Ferrioxamine B Receptor Gene	4
Involvement of <i>Bmal1</i> and <i>Clock</i> in Bromobenzene Metabolite-Induced Diurnal Renal Toxicity	4