Biological & Pharmaceutical Bulletin

Article	Citations
Changes in Pharmacy Students’ Awareness of Hepatitis B Patients through Patient Lectures as Humanity Education: Findings from Questionnaire Surveys of Face-to-Face and Simultaneous Remote Classes	49
Errata for Biological and Pharmaceutical Bulletin	43
Effects of Disodium Cromoglycate Treatment in the Early Stage of Diabetic Nephropathy: Focus on Collagen Deposition	33
Genipin Attenuates Sepsis-Induced Splenocyte Apoptosis <i>via</i> the Inhibition of Endoplasmic Reticulum Stress	32
Protective Effect of Pemafibrate Treatment against Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats	30
Dietary Zinc Deficiency Induces Ca<sub>v</sub>3.2-Dependent Nociceptive Hypersensitivity in Mice	28
Effect of Chronic Ethanol Consumption on Exogenous Glucose Metabolism in Rats Using [1-<sup>13</sup>C], [2-<sup>13</sup>C], and [3-<sup>13</sup>C]glucose Breath Tes	26
Sorghum (<i>Sorghum bicolor</i>) Extract-Induced Adipogenesis Is Independent of PPARγ Ser273 Phosphorylation in 3T3-L1 Adipocytes	22
Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database	20
Effect of Amino Acid Substitution on Cell Adhesion Properties of Octa-arginine	18
Chlorogenic Acid Inhibited Epithelial–Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy	17
Cross-Cancer Type Evaluation of Potential Interstitial Lung Disease Complications of Immune Checkpoint Inhibitors Using JADER	17
Comparison of Addition of Indications for Antineoplastic Agents Approved in the United States and Japan from 2001 to 2020	17
Association between Weight Gain and Sex-Related Differences through 5-Fluorouracil Administration	17
Development of a Specific Competitive ELISA for Plasma Adropin Levels and Its Application to Investigating Energy Homeostasis in Mice	17
Identification and Physiological Analysis of Novel Riboflavin Transporter RFVT	16
Characterization of Potentially Inappropriate Medications That Need Special Attention in the Elderly with Dementia by Analyzing Pharmacy Claims Data	16
Development of an Analytical Method for Unsaturated Disaccharides from Heparan Sulfate Using Dansylhydrazine Derivatization and High-Performance Liquid Chromatography with Fluorescence Detection	15
Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport	15
Pharmacological Characteristics of Extracellular Ca<sup>2+</sup> Influx Pathways Responsible for Platelet-Activating Factor-Induced Contractions in Rat Esophagus Smooth Muscle: Involvement	15
Impact of Drugs and Patient Characteristics on Life Expectancy during the Induction Phase of Dialysis	14
New Directions for Advanced Targeting Strategies of EGFR Signaling in Cancer	14
Effect of Celecoxib Administration on the Skin of 40-Week-Old Mice	14
Process Optimization of Charge-Reversible Lipid Nanoparticles for Cytosolic Protein Delivery Using the Design-of-Experiment Approach	14
Target Therapeutic Ranges of Anti-MRSA Drugs, Linezolid, Tedizolid and Daptomycin, and the Necessity of TDM	14

Selective Inhibitory Effect of Hesperetin on the Automaticity of the Guinea Pig Pulmonary Vein Myocardium	14
Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression	14
Vitamin K3 Suppresses Pyroptosis in THP-1 Cells through Inhibition of NF-κB and JNK Signaling Pathways	14
Russelioside A, a Pregnane Glycoside from <i>Caralluma tuberculate</i>, Inhibits Cell-Intrinsic NF-κB Activity and Metastatic Ability of Breast Cancer Cells	14
Shimanami Leaf Intake Affects Bowel Movement and Intestinal Microbiota in Mice	14
Usefulness of an Intermittently Scanned Continuous Glucose Monitoring System for Risk Management of Individuals without Diabetes in Japan	13
Population Pharmacokinetic Model of Amiodarone and <i>N</i>-Desethylamiodarone Focusing on Glucocorticoid and Inflammation	13
Pharmacological Investigation of Hypoalbuminemia on the Prolonged and Potentiated Action of Midazolam in Rats	13
Lipopolysaccharide Priming Exacerbates Anaphylatoxin C5a-Induced Anaphylaxis in Mice	12
Clozapine Induces Neuronal Activation in the Medial Prefrontal Cortex in a Projection Target-Biased Manner	12
A Reactive Metabolite of Clozapine Induces Hematopoietic Toxicity in HL-60 Cells Undergoing Granulocytic Differentiation through Its Effect on Glutathione Metabolism	12
3-Nitropropionic Acid Enhances Ferroptotic Cell Death <i>via</i> NOX2-Mediated ROS Generation in STHdhQ111 Striatal Cells Carrying Mutant Huntingtin	12
Magnitude of Fruit Juice–Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices	12
RasGRP2 Attenuates TAGE Modification of eNOS in Vascular Endothelial Cells	12
LncRNA <i>Gm16638-201</i> Inhibits the 14-3-3Ɛ Pathway in the Murine Prefrontal Cortex to Induce Depressive Behaviors	12
Fosphenytoin Alleviates Herpes Simplex Virus Infection-Induced Provoked and Spontaneous Pain-Like Behaviors in Mice	12
Cascade Enzyme Catalysis Supported Starvation and Photodynamic Synergistic Therapy for Breast Cancer	12
Indomethacin, a Non-steroidal Anti-inflammatory Drug, Induces Skin Dryness <i>via</i> PPARγ in Mice	12
Amodiaquine Analogs Are Potent Inhibitors of Interleukin-6 Production Induced by Activation of Toll-Like Receptors Recognizing Pathogen Nucleic Acids	12
Inhibition of p38 Mitogen-Activated Protein Kinases Attenuates Methylmercury Toxicity in SH-SY5Y Neuroblastoma Cells	11
L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α<sub>1B</sub> Receptor at the Second Transmembrane Interface	11
Piperacillin Exacerbates Vancomycin-Induced Toxicity in Renal Proximal Tubular Cells	11
Subsidy Programs for Herpes Zoster Vaccination in Japanese Municipalities	11
Evaluation of the Potential Inhibitory Effects of Medications for Detrusor Overactivity on Platelet-Activating Factor (PAF)-Induced Mechanical Activity in Guinea Pig Bladder Smooth Muscle	11
Kuanoniamine C Suppresses Adipogenesis and White Adipose Tissue Expansion by Modulating Mitochondrial Function	11
Inhibition Mechanism of SARS-CoV-2 Infection by a Cholesterol Derivative, Nat-20(S)-yne	11
Foreword	11
Lymphatic Transport and Immune Activation Effect by Locally Administered Extracellular Vesicles from <i>Saccharomyces cerevisiae</i> as Biocompatible Vaccine Adjuvants	11
Foreword	11
Effect of PEGylated Liposomalization of Oxaliplatin on the Gut Microbiota in Mice	11
3′,4′-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT–mTOR and NF-κB Pathways	11
The Role of SGLT2 Inhibitor Ipragliflozin on Cardiac Hypertrophy and microRNA Expression Profiles in a Non-diabetic Rat Model of Cardiomyopathy	11
Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels <i>via</i> VEGF Signaling Pathway Activation by miRNA-126	10
Antidepressant Effect of Intracerebroventricularly Administered Deltorphin Analogs in the Mouse Tail Suspension Test	10
Exploring Cell-Penetrating Peptides as Penetration Enhancers in Eye Drop Formulations Using a Reconstructed Human Corneal Epithelial Model	10
Effect of a Single Dose of Oxaliplatin on the Induction of Peripheral Neuropathy in a Rat Model: An <i>in Vivo</i> Electrophysiological Study	10
Cryopreservation of Hepatocyte Organoid-Derived Cells Generated from Human iPS Cells	10
Dose Individualization of Oral Multi-Kinase Inhibitors for the Implementation of Therapeutic Drug Monitoring	10
Innovative System for Delivering Nucleic Acids/Genes Based on Controlled Intracellular Trafficking as Well as Controlled Biodistribution for Nanomedicines	10
Chronotropic and Inotropic Effects of Sudachitin, a Polymethoxyflavone from the Peel of <i>Citrus sudachi</i> on Isolated Rat Atria and Its Underlying Mechanisms	10
Intracerebroventricular Administration of Dermorphin-Dynorphin Analogs Producing Antidepressant-Like Effects through Activation of μ<sub>1</sub>- and κ-Opioid Receptors in Mice	10
Protective Effects of <i>Pleurotus</i> Species on UVB-Induced Skin Disorders at Clinically Relevant Plasma Concentrations of the Antioxidant Ergothioneine in Hairless Mice	9
Structural Perspective of the Double-Stranded RNA Transport Mechanism by SID-1 Family Proteins	9
Prospective Analysis of Factors Influencing Inter-Individual Variation in Trough Plasma Voriconazole Concentrations in Older Patients—Impact of High <i>α</i>1-Acid Glycoprotein Levels	9
Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy	9
Carbon Monoxide Alleviates Post-ischemia–reperfusion Skeletal Muscle Injury and Systemic Inflammation	9
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy	9
Effects of Antibacterial Agents on Cancerous Cell Proliferation	9
Antidepressant-Like Effects of Intracerebroventricular Injection of Nociceptin Analogs in Mice	9
Cloperastine Reduces IL-6 Expression <i>via</i> Akt/GSK3/Nrf2 Signaling in Monocytes/Macrophages and Ameliorates Symptoms in a Mouse Sepsis Model Induced by Lipopolysaccharide	9

Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells	9
ELK3 Targeting AEG1 Promotes Migration and Invasion of Ovarian Cancer Cells under Hypoxia	9
Substrate-Dependent Alteration in the <i>C</i>- and <i>O</i>-Prenylation Specificities of <i>Cannabis</i> Prenyltransferase	9
Clinical Analysis and <i>in Vitro</i> Correlation of BCRP-Mediated Drug–Drug Interaction in the Gastrointestinal Tract	9
Magnetic Delivery of Paclitaxel by Magnetic Anionic Liposome/Atelocollagen Complexes for Targeted Cancer Therapy	9
Foreword	9
Deproteination of Serum–Drug Samples Utilizing a Temperature-Responsive Spin Column Containing Thermoresponsive Polymer Brush-Modified Beads	9
Platelets Affect the Activity of Amino Acid Transporter SNAT4 in HuH-7 Human Hepatoma Cells	9
Self-controlled Case Series Study for Acute Kidney Injury after Starting Proton Pump Inhibitors or Potassium-Competitive Acid Blocker in Patients with Cancer Using a Large Claims Database	9
Ginsenosides in <i>Panax ginseng</i> Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation	8
Effective Location of the Plantar Surface of the Hind Paw for the Evaluation of Mechanical Hyperalgesia Using von Frey Filaments in Mice Treated with Paclitaxel	8
Evaluation of Transport Activity Using Mouse Jejunal Epithelial Cell Monolayer Culture System	8
Phosphatidylcholine-Plasmalogen-Oleic Acid Has Protective Effects against Arachidonic Acid-Induced Cytotoxicity	8
Infliximab Treatment Persistence among Japanese Patients with Chronic Inflammatory Diseases: A Retrospective Japanese Claims Data Study	8
Seasonal Variations in Drug-Related Erythema Multiforme: A Time Series Analysis Using the JADER Database	8
A Novel Cross-Immune Antigen Vaccine Platform for Influenza Virus Type A	8
The Cyclin-Dependent Kinase 4/6 Inhibitor Abemaciclib Is Tolerated Better than Palbociclib by Advanced Breast Cancer Patients with High Serum Albumin Levels	8
Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin	8
RasGRP2 Attenuates Oxygen Deprivation-Induced Autophagy in Vascular Endothelial Cells	8
Anacardic Acid Derivatives Isolated from Fungal Species <i>Tyromyces fissilis</i> as New Histone Acetyltransferase Inhibitors	8
Impact of Polypharmacy and Risk Factors for Exacerbation of Lower Urinary Tract Symptoms in Patients with Urological Conditions: A Retrospective Study in a Japanese Municipal Hospital	8
Ononin Relieves the Thyroid Cancer Progression through Targeting the Caspase 3 and CD274 Expression Levels	8
Influence of Size, Flexibility, Hydrophobicity, Surface Charge, and Surface Chemistry on the Biodistribution of Orally Administered Polymer Nanoparticles	8
Methylselenocysteine Potentiates Etoposide-Induced Cytotoxicity by Enhancing Gap Junction Activity	8
Panobinostat, a Histone Deacetylase Inhibitor, Reduces LPS-Induced Expression of Inducible Nitric Oxide Synthase in Rat Immortalized Microglia HAPI Cells	8
Quercetin, a Natural Dietary Flavonoid, Emerges a Novel USP7 Inhibitor with Anti-colorectal Cancer Effects	8
Characterization of CNS Network Changes in Two Rodent Models of Chronic Pain	8
Effect of Orally Ingested Water Containing H<sub>2</sub>-Filled Ultrafine Bubbles (UFBs) on Ethanol-Induced Oxidative Stress in Rats	8
Association between Early Guanfacine Discontinuation and Somnolence for Attention-Deficit/Hyperactivity Disorder	8
Influence of the Th1 Cytokine Environment on CCL5 Production from Langerhans Cells	7
Saikosaponin A Inhibits Growth of Human Bladder Carcinoma T24 and 5637 Cells Both <i>in Vitro</i> and <i>in Vivo</i>	7
Extracellular Vesicles Derived from the Serum of <i>Seriola quinqueradiata</i> Induce Human Umbilical Vein Endothelial Cell Proliferation through Angiogenic Signaling	7
Risk Factors for Treatment Transition in Patients with Low-Risk Atrial Fibrillation Patients Undergoing Anticoagulation Monotherapy: A Large Claims Database Study in Japan	7
Longitudinal Trend in Antimicrobial Susceptibility among <i>Haemophilus influenzae</i>: A Single-Centre Study in Japan	7
Point Mutation Analysis of the Drug Efflux Pump MexB in Clinical Isolates of <i>Pseudomonas aeruginosa</i>	7
Foreword	7
Photoacoustic Imaging for Monitoring Calcium Dynamics in the Heart	7
Qualitative Changes in Collagen Induced by UV Irradiation Affect Its Interaction with Cells	7
Andrographolide/Phospholipid/Cyclodextrin Complex-Loaded Nanoemulsion: Preparation, Optimization, <i>in Vitro</i> and <i>in Vivo</i> Evaluation	7
Endogenous SOLOIST/MRTFB i4, a Neuronal Isoform of MKL2/MRTFB, Positively and Negatively Regulates SRF Target Immediate Early Genes in Neuro-2a Cells	7
Skin Dryness Induced in the KK-Ay/TaJcl Type 2 Diabetes Mouse Model Deteriorates Following Dapagliflozin Administration	7
Contamination-Free Milling of Ketoprofen Nanoparticles Using Mannitol Medium and Hoover Automatic Muller: Optimization of Effective Design of Experiment	7
Ketogenic Diet Alleviates Mechanical Allodynia in the Models of Inflammatory and Neuropathic Pain in Male Mice	7
Analysis of Risk Factors for Developing Tuberculosis in Patients Who Received Prophylactic Latent Tuberculosis Infection Treatment with Experience of Biologic Medications	7
Mogroside Alleviates Diabetes Mellitus and Modulates Intestinal Microflora in Type 2 Diabetic Mice	7
Siweixizangmaoru Decoction Ameliorated Type II Collagen-Induced Arthritis in Rats <i>via</i> Regulating JAK2–STAT3 and NF-κB Signaling Pathway	7
Curcumin Is Primarily Distributed in Lung, Spleen and Liver, Metabolized to Glucuronide and Sulfate, and Excreted through Bile and Urine by Using an Amorphous Curcumin Formulation with High Absorbabil	7
Protective Effects of <i>Coptis chinensis</i> Rhizome Extract and Its Constituents (Berberine, Coptisine, and Palmatine) against α-Synuclein Neurotoxicity in Dopaminergic SH-SY5Y Cells	7
The Potential Effects of 2,3,4-Trihydroxybenzophenone on the Transient Cerebral Ischemic Stroke in Male Mice	7
Functional Analysis of Modified Caco-2 Cells Carrying CES2A1 as a Model for Intestinal Absorption of Prodrugs	7
Development of a Nanocarrier-Based Splenic B Cell-Targeting System for Loading Antigens <i>in Vitro</i>	6
Renal Metabolomics Study and Critical Pathway Validation of Shenkang Injection in the Treatment of Chronic Renal Failure	6
Probes with Tailored Pharmacokinetics for Radiotheranostics	6
Impact of Bridged Nucleic Acid Positions within Blocking Oligonucleotides on DNA Amplification Inhibition in Wild-Type Blocking PCR	6
Ameliorative Effects of Sweeteners on a Mouse Jet Lag Model	6
Anticancer Effects of New Disulfiram Analogs	6
Effects of Body Composition on Renal Function Estimates in Older Patients	6
Octa-arginine and Octa-lysine Promote Cell Adhesion through Heparan Sulfate Proteoglycans and Integrins	6
Fabrication of 3D-Printed Contact Lens Composed of Polyethylene Glycol Diacrylate for Controlled Release of Azithromycin	6
Goji Berry Juice Prevents Tumor Necrosis Factor Alpha-Induced Xerostomia in Human Salivary Gland Cells	6
Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment	6
Pinpoint Insertion of a Single Amino Acid into a Framework Region Enhanced the Affinity of an Anti-cortisol Antibody to Enable Sensitive Immunoassays	6
<i>Ajania purpurea</i> Extract Attenuates LPS-Induced Inflammation in RAW264.7 Cells and Peritonitis Mice	6
Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain	6
Biochemical Characterizations of the Putative Amidase Endolysin Ecd18980 Catalytic Domain from <i>Clostridioides difficile</i>	6
<i>Salvia miltiorrhiza</i> Prevents Methylglyoxal-Induced Glucotoxicity <i>via</i> the Regulation of Apoptosis-Related Pathways and the Glyoxalase System in Human Umbilical Vei	6
Assessment of Risk of Acidosis in Patients with Mild-to-Moderate Chronic Kidney Disease Treated with Intravenous Branched-Chain Amino Acid-Enriched Solution: A Propensity Score Matching Analysis	6
Evaluation of Puberulic Acid-Induced Nephrotoxicity Using 3D-RPTEC	6
Machine Learning-Based Model for Estimating Vancomycin Maintenance Dose to Target the Area under the Concentration Curve of 400–600 mg·h/L in Japanese Patients	6
Blocking CXC Motif Chemokine Ligand 2 Ameliorates Diabetic Peripheral Neuropathy <i>via</i> Inhibiting Apoptosis and NLRP3 Inflammasome Activation	6
Medical Economic Benefit Derived from the Use of Tracing Reports by Pharmacy-Based Pharmacists for Pharmaceutical Intervention and Reduction of Leftover Medicines	6
Analysis of Risk Factors for Infusion-Related Reactions Following Rituximab Administration in Patients with Desensitization before Renal Transplantation	6
Effects of Ingested Water Volume on Oral Absorption of Fenofibrate, a BCS Class II Drug, from Micronized and Amorphous Solid Dispersion Formulations in Rats	6
Usefulness of the Albumin–Bilirubin Score in Determining the Initial Dose of Voriconazole for Patients with Liver Cirrhosis	6
Biotransformation of Morphinone and Its Glutathione Adduct Derived from Morphine by Anaerobic Gut Microbes in Guinea Pigs	6
Structural Impact Assessment of Cytochrome P450 2A13 Polymorphisms Using Molecular Dynamics Simulations	6
A Survey of Near-Miss Dispensing Errors in Hospital Pharmacies in Japan: DEPP-J Study—Multi-Center Prospective Observational Study—	6
Inhibitory Actions of Antidepressants, Hypnotics, and Anxiolytics on Recombinant Human Acetylcholinesterase Activity	6
Serum Concentrations of Infliximab and IL-6 for Predicting One-Year Discontinuation of Infliximab Treatment Owing to Secondary Non-response in Patients with Rheumatoid Arthritis	6
Mechanism of Human Cytomegalovirus-Induced Epithelial–Mesenchymal Transition in Glioma Cells <i>via</i> the Upregulation of RIP2 Expression	6

Removal of Soluble ACE2 in VeroE6 Cells by 17β-Estradiol Reduces SARS-CoV-2 Infectivity	6
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte	6
Liver and Plasma Concentrations of Food Chemicals after Virtual Oral Doses Extrapolated Using <i>in Silico</i> Estimated Input Pharmacokinetic Parameters to Confirm Reported Liver Toxicity	6
Ciclesonide Inhibits SARS-CoV-2 Papain-Like Protease <i>in Vitro</i>	6
Visualization and Optical Manipulation of the Erectile Tissue, Penile Corpus Cavernous	6
Emedastine Inhibits Th1 and Th2 Cell Differentiation Mediated by Mast Cells	6
Phospholipid Scramblase 1 Localizes Proximal to Sphingomyelin Synthase Isoforms but Is Not Involved in Sphingomyelin Synthesis	6
Development of SCAR Markers to Identify Medicinal Cultivars of <i>Paeonia lactiflora</i>	6
Rapid Screening Detection of Genetically Modified Papaya by Loop-Mediated Isothermal Amplification	6
Foreword	6
Development of a Novel Gastric Process Simulation Model: The Successful Assessment of Bioequivalence and Bioinequivalence of a Biopharmaceutics Classification System Class II Weak Acid Drug	6
The Mechanism of 5-Fluorouracil-Induced Hyperpigmentation in HRM-2 Hairless Mice: Focus on the Increase of Blood Vessels	6
Feasibility Study of Dendrimer-Based TTR-CRISPR pDNA Polyplex for Ocular Amyloidosis <i>in Vitro</i>	6
New Drug Delivery Systems for Stable Oral Absorption: Theory, Strategies, and Applications	6
Risk Assessment for Heart Failure in Patients with Type 2 Diabetes Mellitus Treated with Dipeptidyl Peptidase 4 Inhibitor Using a Large Claims Dataset	6
Impact of Gut Microbiota on the Pharmacokinetics of Glycyrrhizic Acid in Yokukansan, a Kampo Medicine	5
Proteasome Inhibition Induces IRF1 Downstream Molecules Independently of JAK Activity in Cancers	5
Decreased Analgesic Effect of Tramadol in Japanese Patients with CYP2D6 Intermediate Metabolizers after Orthopedic Surgery	5
<i>Astragalus</i> Polysaccharide Suppresses Cell Proliferation and Invasion by Up-Regulation of miR-195-5p in Non-small Cell Lung Cancer	5
Calculation of Human Melatonin Partial Metabolic Clearance in Healthy Adult Volunteers for Investigation of a Novel <i>in Vivo</i> CYP1A2 Phenotyping Method: A Pilot Study	5
Nanaomycin K Inhibited Cell Proliferation and Epithelial–Mesenchymal Transition in Renal Cell Carcinoma	5
Assessment of Diagnosis Timing of Attention-Deficit/Hyperactivity Disorder in Working-Age Workers with Psychiatric Diseases Using Large Claims Data	5
Simple Cytosolic and Nuclear Introduction of Boron Compounds Using Cationic Lipids to Enhance Cancer Cell-Killing Activity in Boron Neutron Capture Therapy	5
Selexipag Improves Lipopolysaccharide-Induced ARDS on C57BL/6 Mice by Modulating the cAMP/PKA and cAMP/Epac1 Signaling Pathways	5
Therapeutic Drug Monitoring of Antibody Drugs	5
Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation	5
Predicting the Safety of Ocular Iontophoresis Using Reconstructed Human Corneal Epithelial Cells	5
Synergistic Effect of Baculovirus-Mediated Endostatin and Angiostatin Combined with Gemcitabine in Hepatocellular Carcinoma	5
Expression of the Discoidin Domain Receptor Family Depended on Glucose and Their High Expression in Arterial Tissues in the Rat Model of Type 2 Diabetes	5
Exploring IDI2-AS1, OIP5-AS1, and LITATS1: Changes in Long Non-coding RNAs Induced by the Poly I:C Stimulation	5
Calsequestrin-1 Deficiency Induced Malignant Hyperthermia-Like Skeletal Injury through Mitochondrial Disorder	5
<i>MicroRNA-5572</i> Is Associated with Endoplasmic Reticulum Stress Responses in Low Zinc Treated and SOD1 G85R-Transfected HEK293 Cells	5
Oligodendroglia Generate Vascular Mural Cells and Neurons in the Adult Mouse Brain	5
A Novel Lithocholic Acid Derivative Upregulates Detoxification-Related Genes in Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids	5
Notice of Addendum for Biological and Pharmaceutical Bulletin	5
Induction of Melanin Synthesis by <i>Pueraria lobata</i> Leaves in B16 Murine Melanoma Cells and Three-Dimensional Human Skin Equivalent	5
Proton Pumping ATPases: Rotational Catalysis, Physiological Roles in Oral Pathogenic Bacteria, and Inhibitors	5
Descriptive Study on a Nationwide Exploratory Questionnaire Survey of Emergency Contraceptive Pills and Their Sexual History and Knowledge in Japan	5
Gambogenic Acid Inhibits Basal Autophagy of Drug-Resistant Hepatoma Cells and Improves Its Sensitivity to Adriamycin	5
Topical Xerostomia Treatment with Hyaluronate Sheets Containing Pilocarpine	5
Wogonin Attenuates Bleomycin-Induced Pulmonary Fibrosis and Oxidative Stress Injury <i>via</i> the MAPK Signaling Pathway	5
Inhibition of TRPC4/5 Channel Is Effective in Protecting against Histamine-Induced Hyperpermeability by Blocking Ca<sup>2+</sup> Influx in Lung Microvascular Endothelial Cells	5
Quantitative Assessment of the Post-translational Modifications of Human Serum Albumin by Dimethyl Trisulfide	5
Development of a Highly Sensitive and Rapid Liquid Chromatography–Tandem Mass Spectrometric Method Using a Basic Mobile Phase Additive to Determine the Characteristics of the Urinary Metabolites for N	5
LncRNA Snhg5 Attenuates Status Epilepticus Induced Inflammation through Regulating NF-κΒ Signaling Pathway	5
Detection of Characteristic Phosphatidylcholine Containing Very Long Chain Fatty Acids in Cerebrospinal Fluid from Patients with X-Linked Adrenoleukodystrophy	5
Modeled Rat Hepatic and Plasma Concentrations of Chemicals after Virtual Administrations Using Two Sets of <i>in Silico</i> Liver-to-Plasma Partition Coefficients	5
Efficacy of Enhanced Antimicrobial Stewardship Team Interventions for Patients Receiving Meropenem and Tazobactam/Piperacillin	5
Curculigoside Represses the Proliferation and Metastasis of Osteosarcoma <i>via</i> the JAK/STAT and NF-κB Signaling Pathways	5
Effect of Growth Hormone Receptor Deficiency on Androgen-Associated Gene Expression of Hepatic Drug Metabolizing Enzymes and Drug Transporters in Pigs	5
Transcriptional Mechanism of the Mouse β4-Galactosyltransferase 6 Gene in Mouse Neuroblastoma Cell Line Neuro-2a	5
Multifactorial Alterations in Lacosamide Exposure in an Elderly Woman with Symptomatic Epilepsy and Tuberculous Pleurisy: A Case Report	5
SRF and SRF Cofactor mRNA Expression Is Differentially Regulated by BDNF Stimulation in Cortical Neurons	5
New Maintenance Culture Method for Intestinal Stem Cells Derived from Human Induced Pluripotent Stem Cells	5
Current Status and Perspectives of Therapeutic Antibodies Targeting the Spike Protein S2 Subunit against SARS-CoV-2	5
Functional Domain Mapping of Werner Interacting Protein 1 (WRNIP1)	5
Differential Suppressive Effects of Rho Kinase Inhibitor Fasudil on Serotonin- and Noradrenaline-Induced Contractions of Human Internal Thoracic Arteries and Saphenous Veins	5
Mitochondrial Coenzyme Q<sub>10</sub> Delivery Improves Energy Production in Rat Cardiac Myoblasts and Duchenne Muscular Dystrophy Model Rat Cardiomyocytes	5
Solubilizing Effect of Caffeine on Precipitate of Risperidone Oral Solution and Tea Beverage	5
Association between Inhalation Instruction Method in Community Pharmacies and Inhaler Device Handling Error in Patients with Obstructive Lung Disease: An Evaluation of the Impact of Practical Demonstr	5
Anti-atrial Fibrillatory Effects of the TRPC3 Channel Inhibitor Pyrazole-3 in Rats with Atrial Enlargement Induced by Chronic Volume Overload	5
<i>Cry2</i> Alleviates Cisplatin-Induced Cytotoxicity in Mouse Renal Cortex Tubular Cell Lines	5
Royal Jelly Maintains Epidermal Stem Cell Properties by Repressing Senescence	5
Cathepsin G-Induced Cell Aggregation of Breast Cancer MCF-7 Decreases Doxorubicin Sensitivity in a Hypoxia-Inducible Factor-Independent Mechanism	5
Possible Involvement of DNA Methylation and Protective Effect of Zebularine on Neuronal Cell Death after Glutamate Excitotoxity	5
Polyphyllin E Inhibits Proliferation, Migration and Invasion of Ovarian Cancer Cells by Down-Regulating the AKT/NF-κB Pathway	5
Characterization of Novel Cell-Adhesive Peptides for Biomaterial Development	5
Efficacy of Naldemedine on Intestinal Hypomotility and Adhesions in Rodent Models of Postoperative Ileus	5
BET Inhibitors Induce p53-Independent Growth Arrest in HCT116 Cells <i>via</i> Epigenetic Control of the E2F1/c-<i>MYC</i> Axis	5
Pharmacological Studies on the Ca<sup>2+</sup> Influx Pathways in Platelet-Activating Factor (PAF)-Induced Mouse Urinary Bladder Smooth Muscle Contraction	5
Polyunsaturated Fatty Acid-Derived Lipid Mediators That Regulate Epithelial Homeostasis	5
Enhanced Type I Collagen Synthesis in Fibroblasts by Dermal Stem/Progenitor Cell-Derived Exosomes	5
Prevention of Renal Interstitial Fibrosis by Suplatast in a Mouse Model	5
PI3K/AKT1 Signaling Pathway Mediates Sinomenine-Induced Hepatocellular Carcinoma Cells Apoptosis: An <i>in Vitro</i> and <i>in Vivo</i> Study	5
A Complex of Type I Platelet-Activating Factor Acetylhydrolase (PAF-AH) Catalytic Subunits Switches from α1/α2 Heterodimer to α2/α2 Homodimer during Adipocyte Differentiation of 3T3-L1 Cells	5
Vitexin Attenuates Non-alcoholic Fatty Liver Disease Lipid Accumulation in High Fat-Diet Fed Mice by Activating Autophagy and Reducing Endoplasmic Reticulum Stress in Liver	5
Construction of a Temperature-Sensitive Shuttle Vector between Lactic Acid Bacteria and <i>Escherichia coli</i> and Its Application to a Tn<i>10</i>-Based Random Mutagenesis To	5
Clinical Profiles of Japanese Patients with Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Collected by a Nationwide System from 2006 to 2023	5
Catheter-Related Bloodstream Infection in Patients Receiving Vitamin-Enriched Peripheral Parenteral Nutrition: A Retrospective Cohort Study	5
Comparison of the Speed of Enrollment for Clinical Trials Conducted by Japanese and Global Pharmaceutical Companies	5
Qualification of <i>In Vitro</i> Dissolution Absorption System 2 (IDAS2) with Caco-2 and MDCK Cell Monolayers: Dose Sensitivity Study Using BCS Class I and III Drugs	5
Development of a Method of Liquid Chromatography Coupled with Tandem Mass Spectrometry for Simultaneous Determination of Linezolid and Tedizolid in Human Plasma	5
Efficacy of Zinc Acetate in the Treatment of Zinc Deficiency in Elderly Inpatients and Effect of Total Dose on Its Replacement Therapy	5
Quetiapine Reverses the Behavior and Myelination in Alcohol-Exposed Gestational Diabetes Mellitus Offspring Mice <i>via</i> ERK1/2 Signaling	5
Non-neuronal Cholinergic Muscarinic Acetylcholine Receptors in the Regulation of Immune Function	5
Combination Therapy with Betamethasone and Josamycin Demonstrates Superior Therapeutic Efficacy in an NC/Nga Mouse Model of Atopic Dermatitis	5
Effectiveness of Pharmacists’ Recommendations for Dental Examinations for Prevention of Medication-Related Osteonecrosis of the Jaw	4
Probing the Deoxyflavonoid Biosynthesis: Naringenin Chalcone Is a Substrate for the Reductase Synthesizing Isoliquiritigenin	4
CRISPRa Analysis of Phosphoinositide Phosphatases Shows That TMEM55A Is a Positive Regulator of Autophagy	4
Exposure-Response Analysis and Mechanism of Ginkgolide B’s Neuroprotective Effect in Acute Cerebral Ischemia/Reperfusion Stage in Rat	4
Development of Low-Density Lipoprotein Receptor-Targeted Liposomes for Enhanced Accumulation in Ischemia/Reperfusion Environment	4
Incidence of Hepatobiliary Injury in Patients Undergoing Dai-kenchu-to Administration Following Gastrectomy: A Retrospective Cohort Study Using Japanese Diagnosis Procedure Combination Data	4
Development and Stability of a New Transdermal Formulation of Pregabalin for Skin Permeation	4
Impact of Hepatitis B Surface and Core Antibody Levels on Hepatitis B Virus Reactivation	4
Application Site of Transdermal Scopolamine Influences Efficacy and Drug Concentration in Salivary Glands in Rats	4