OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Clinical Biochemistry and Nutrition is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Development of sandwich ELISAs for detecting glucagon-like peptide-1 secretion from intestinal L-cells and their application in STC-1 cells and mice	41
DNA-mediated ZNF649 downregulation modulates the Hedgehog signaling pathway to ‍reduce the sensitivity of gastric cardia cancer to ‍5-FU	22
TRIM62 knockdown by inhibiting the TLR4/NF-κB pathway and NLRP3 inflammasome attenuates cognitive impairment induced by diabetes in mice	19
A cross-sectional study on the relationship between nutrient/food intake and gut microbiota in frailty among older community residents: The Kyotango study	19
Characterization of the gut phageome of Japanese patients with ulcerative colitis under endoscopic remission	18
Association between dietary fiber intake and mortality in populations with accelerated biological aging: a study based on NHANES 1999–2018 data	17
Reduced abundance of butyric acid-producing bacteria in the ileal mucosa-associated microbiota of ulcerative colitis patients	16
Mechanism of enteral nutrition in regulating Tfh/Tfr immune imbalance in colorectal cancer via the TLR4 signaling pathway	16
Quenching effect of cerium oxide nanoparticles on singlet oxygen: validation of the potential for reaction with multiple reactive oxygen species	15
Sirtuin 3 ameliorates inflammatory bowel disease via inhibiting intestinal inflammation and oxidative stress	15
Newly developed evaluation for intestinal permeability using <i>Caenorhabditis elegans</i>: protective effects of agaro-oligosaccharides on ‍intestinal permeability	14
Association of lysophosphatidic acid molecules with liver fibrosis: different roles indicated	13
Comparison of the oxidative profiles before and after revascularization in peripheral arterial disease: a pilot study	13
Nobiletin, a polymethoxylated flavonoid from citrus, enhances IL-4 production in DO11.10 mice via antigen-presenting cells	13
Plasma-activated medium exerts tumor-specific inhibitory effect on hepatocellular carcinoma via disruption of the salvage pathway	13
Induction of <i>MYCN</i>-amplified neuroblastoma differentiation through NMYC suppression using PPAR-γ antagonist	13
Relationships between body mass index and constipation, gastroesophageal reflux disease, stool forms based on the Bristol Stool Form Scale, and education level: results from an internet survey in Japa	12
LC/MS/MS detection of uric acid oxidation metabolites to evaluate reactive oxygen and nitrogen species <i>in vivo</i> with application to pseudo-inflammation	12
8-Prenylnaringenin suppresses obesity in high-fat diet-fed C57BL/6J mice via adiponectin secretion	12
Reactive oxygen species generation by photothermal effects of adhesive near-infrared agents on the plasma membrane	11
Gut dysbiosis induced by a high-salt diet aggravates atherosclerosis by increasing the absorption of saturated fatty acids in ApoE-deficient mice	10
A mixed antioxidant supplement improves cognitive function, and coordination in aged mice	10
Shear stress stimuli-induced erythrocytes’ mechanical damage, and its relation to erythrocytes’ membrane oxidation and cellular aging	10
Balance of the prooxidant and antioxidant system is associated with mortality in critically ill patients	9
Intragastric bacterial infection and endoscopic findings in <i>Helicobacter pylori</i>-negative patients	9

Fat-free oral nutritional supplements for patients after acute illness: a prospective observational study	9
Linear association between aging and decreased blood thiol antioxidant activity in patients with cataract	8
Analysis of serum zinc level in patients with severe trauma	8
Inhibition of ALA dehydratase activity in heme biosynthesis reduces cytoglobin expression which is related to the proliferation and viability of keloid fibroblasts	8
GPRC5A regulates proliferation and oxidative stress by inhibiting the STAT3/Socs3/c-‍MYC pathway in hepatocellular carcinoma	8
Poricoic acid a inhibits mitochondrial dysfunction in myocardial infarction by activating SIRT3	8
HIF1α/CCL7/KIAA1199 axis mediates hypoxia-induced gastric cancer aggravation and glycolysis alteration	8
Twendee X, a mixed antioxidant supplement, improves cognitive function, coordination, and neurotrophic factor expression in long-term vitamin E-deficient mice	8
NEK7 inhibition attenuates Aβ<sub>42</sub>-induced cognitive impairment by regulating TLR4/NF-κB and the NLRP3 inflammasome in mice	8
Association between comprehensive dietary antioxidant index and stroke: mediating role of ‍oxidative stress	7
Involvement of α-klotho in growth hormone (GH) signaling	7
Background factors of idiopathic peptic ulcers and optimal treatment methods: a multicenter retrospective Japanese study	7
The effects of lutein, zeaxanthin and anthocyanins supplementation on visual function and vision protection in healthy school-‍aged children: a single-center prospective randomized controlled study	7
Association of serum vitamin D and serum vitamin C with the risk of melanoma among adults in the United States: a cross-sectional analysis of 2003–2006 and 2017–2018 NHANES data	7
Evaluation of malnutrition by objective nutritional indexes and predictors in hospitalized patients with COVID-19	7
Adiponectin inhibits chemokine-induced cell migration via direct interaction with platelet factor 4	7
Modulations of the mTORC2–GATA3 axis by ‍an ‍isorhamnetin activated endosomal–lysosomal system of the J774.1 macrophage-like cell line	7
Enhancement of cytotoxic effects with ALA-PDT on treatment of radioresistant cancer cells	7
Sanguinarine attenuates hypoxia/reoxygenation-triggered H9c2 cell injury through activation of the Nrf2/NLRP3 pathway	6
Application of regulation of reactive oxygen species and lipid peroxidation to disease treatment	6
Effects of ergothioneine on oxidative DNA damage and immune response induced by circadian rhythm disturbance in mice	6
Effects of luseogliflozin treatment on hyperglycemia-induced muscle atrophy in rats	6
High poly-γ-glutamic acid-containing natto improves lipid metabolism and alters intestinal microbiota in mice fed a high-fat diet	6
Lipoprotein(a): structural basis, bidirectional risk, and therapeutic frontiers	6
Andrographolide derivative CX-10 alleviates ulcerative colitis by modulating autophagy and cellular stress	6
<i>N</i>-oxide-based and trioxolane-based fluorescent probes for monitoring labile iron and labile heme: an update	6
Association between upper limb muscle quality and knee osteoarthritis in dynapenia: an observational cross-sectional study	6
Reducing early pregnancy loss with vitamin D<sub>3</sub>: an analysis of serum 1,25-(OH)D<sub>3</sub> modulation and miscarriage risk	6
Optimizing vitamin supplementation via reference interval update of vitamins A, E, B1, and B6 using HPLC	6
FOXM1 transcriptionally activates NEIL3 to inhibit ferroptosis in lung adenocarcinoma cells	6
Exploring the potential targets and molecular mechanisms of cordycepin against gastric cancer based on bioinformatics analysis and network pharmacology	5
Knockdown of LRRK2 inhibits the progression of lung cancer by regulating TLR4/NF-κB pathways and NLRP3 inflammasome	5
Dietary antioxidants and flavonoids intake, and their association with inflammation and oxidative stress parameters in asthmatic women: a case-control study	5
The association between serum zinc level and clinical features in patients with inflammatory bowel disease	5
Effect of fat ingestion on postprandial oxidative status in healthy young women: a pilot study	5
Effects of body position on high-resolution manometry parameters and their correlations with symptoms	5
The ratio of TG/CysC is a significant indicator of nephritis in children with IgA vasculitis	5
Effective disruption of cancer cell membranes by photodynamic therapy with cell membrane-adhesive photosensitizer	5
Acute effect of fructose, sucrose, and isomaltulose on uric acid metabolism in healthy participants	5
Improvement trend for individual health guidance intervention according to Japan clinical guidelines by public health nurses for type 2 diabetes mellitus who visited for medical checkups regularly: a	5
Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-‍L1 expression level reflects tumor resistance	5
Dietary intervention of prebiotic partially hydrolyzed guar gum improves skin viscoelasticity, stratum corneum hydration, and ‍reduction of trans-epidermal water loss: a ‍randomized, double-blind, and	5
Relationship between serum pyridoxal 5'-‍phosphate concentration and cognitive function in older Japanese	5
Protective effects of liposomes encapsulating ferulic acid against CCl<sub>4</sub>-induced oxidative liver damage <i>in vivo</i> rat model	5
Mixed lesions in premalignant colorectal polyps	5