OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Clinical Biochemistry and Nutrition is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Severe grade of melanosis coli is associated with a higher detection rate of colorectal adenoma	27
Effect of matcha consumption on gut microbiota in healthy Japanese individuals: study protocol for a double-blind crossover interventional study	20
The accumulation of copper in the brain of Down syndrome promotes oxidative stress: possible mechanism underlying cognitive impairment	19
Cardiac robustness regulated by reactive sulfur species	15
Characterization of the gut phageome of Japanese patients with ulcerative colitis under endoscopic remission	15
Low-carbohydrate diets adversely impact the skin of a mouse model of photoaging exposed to ultraviolet B radiation	14
Development of sandwich ELISAs for detecting glucagon-like peptide-1 secretion from intestinal L-cells and their application in STC-1 cells and mice	14
Acute exacerbation of idiopathic pulmonary fibrosis model by small amount of lipopolysaccharide in rats	14
The effect of aging on the antioxidative activity of astaxanthin in human aqueous humor	13
Different associations of specific non-alcoholic beverages with elevated high-sensitivity C-reactive protein in Korean adults: results from the Korea National Health and Nutrition Examination Survey (	12
25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) induces ectopic calcification	11
High poly-γ-glutamic acid-containing natto improves lipid metabolism and alters intestinal microbiota in mice fed a high-fat diet	11
Inhibition of lincRNA-Cox2 alleviates apoptosis and inflammatory injury of lipopolysaccharide-stimulated human bronchial epithelial cells via the Nrf2/HO-1 axis	11
Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells	10
Successful endoscopic hemostasis compared to transarterial embolization in patients with colonic diverticular bleeding	10
Associations of circulating xanthine oxidoreductase activity with cardiometabolic risk markers in overweight and obese Japanese men: a cross-sectional pilot study	10
Effect of tocotrienol on the primary progression of nonalcoholic steatohepatitis in a mouse model	9
Microglial inflammatory reactions regulated by oxidative stress	8
Acute effect of proprotein convertase subtilisin/kexin type 9 inhibitor on oxidized low-density lipoprotein and lipid profile in patients at cardiovascular risk	8
Quenching effect of cerium oxide nanoparticles on singlet oxygen: validation of the potential for reaction with multiple reactive oxygen species	7
The hypotaurine-taurine pathway as an antioxidative mechanism in patients with acute liver failure	7
A randomized, double-blinded study evaluating effect of matcha green tea on human fecal microbiota	7
8-Nitro-cGMP suppresses mineralization by mouse osteoblasts	7
Analysis of long-term serological and histological changes after eradication of <i>Helicobacter pylori</i>	7
SMOC2 promoted vascular smooth muscle cell proliferation, migration, and extracellular matrix degradation by activating BMP/TGF‐β1 signaling pathway	6

The anti-inflammatory and protective role of interleukin-38 in inflammatory bowel disease	6
Sirtuin 3 ameliorates inflammatory bowel disease via inhibiting intestinal inflammation and oxidative stress	6
TRIM62 knockdown by inhibiting the TLR4/NF-κB pathway and NLRP3 inflammasome attenuates cognitive impairment induced by diabetes in mice	6
Application of regulation of reactive oxygen species and lipid peroxidation to disease treatment	6
Metabolic changes induced by TGF-β1 via reduced expression of phosphatidylserine decarboxylase during myofibroblast transition	6
Genetic predicted causal inferences between antioxidants and birth weight	6
Edible bird’s nest extract downregulates epidermal apoptosis and helps reduce damage by ultraviolet radiation in skin of hairless mice	6
Crosstalk between oxygen signaling and iron metabolism in renal interstitial fibroblasts	6
Exploratory analysis of the association between dietary niacin intakes and nonalcoholic fatty liver disease among US adults: 1999-2018 data analysis from the National Health and Nutrition Examination	6
Association between reactive oxygen species production in neutrophils and liver fibrosis in the general population	6
Dose-dependent scavenging activity of the ultra-short-acting β1-blocker landiolol against specific free radicals	6
Role of copper and SOD3-mediated extracellular redox regulation in tumor progression	6
Effect of high-amylose rice “Hoshinishiki” on ‍postprandial glucose levels measured by ‍continuous glucose monitoring in patients with ‍diabetes	6
Relationship between critical care nutrition and post-intensive care syndrome in surviving ventilated patients with COVID-19: a multicenter prospective observational study	6
β-elemene inhibits adipogenesis in 3T3-L1 cells by regulating AMPK pathway	6
Reduced abundance of butyric acid-producing bacteria in the ileal mucosa-associated microbiota of ulcerative colitis patients	5
Association between upper limb muscle quality and knee osteoarthritis in dynapenia: an observational cross-sectional study	5
Targeted deletion of Atg5 in intestinal epithelial cells promotes dextran sodium sulfate-induced colitis	5
Low immunogenicity of vedolizumab determined by a simple drug-tolerant assay in patients with ulcerative colitis	5
Rapid pretreatment for multi-sample analysis of advanced glycation end products and their role in nephropathy	5
The Protective Role of Kakkalide in Sepsis-Induced Intestinal Barrier Dysfunction via Inhibition of NF-κB Pathway Activation	5
Vonoprazan vs lansoprazole for the treatment of artificial gastric ulcer after endoscopic submucosal dissection: a prospective randomized comparative study	5
Lipid-soluble polyphenols from sweet potato exert antitumor activity and enhance chemosensitivity in breast cancer	5
A cross-sectional study on the relationship between nutrient/food intake and gut microbiota in frailty among older community residents: The Kyotango study	5
Comparison of mucosa-associated microbiota in Crohn’s disease patients with and without anti-tumor necrosis factor-α therapy	4
Association between frailty and dietary quality in community-dwelling elderly: data from the 6th Korea National Health and Nutrition Examination Survey (2014–2015)	4
A nutritional intervention that promotes increased vegetable intake in Japanese with non-alcoholic fatty liver disease: a six-month trial	4
Effects of additives on reaction of nucleosides with UV light in presence of uric acid and salicylic acid	4
Changes in plasma-concentration ratios of branched-chain amino acids in acute and convalescent phases of bacterial pneumonia	4
Dietary Combination of Sucrose and Linoleic Acid Increases Intramyocellular Lipid and Impairs Muscle Strength in Female Zucker Diabetic Fatty Rats	4
Retrospective investigation of mesalamine intolerance in patients with ulcerative colitis	4
Association of lysophosphatidic acid molecules with liver fibrosis: different roles indicated	3
Effect of folic acid supplementation on the change of plasma <i>S</i>-adenosylhomocysteine level in Chinese hypertensive patients: a randomized, double-blind, controlled clinical trial	3
Reactions of kynurenic acid with hypobromous acid and hypochlorous acid	3
Eurycomanone from <i>Eurycoma longifolia</i> Jack upregulates neurotrophin-3 gene expression in ‍retinal Müller cells <i>in vitro</i>	3
Long-lasting renal dysfunction following tacrolimus induction therapy in ulcerative colitis patients	3
Monascus pigment prevent the oxidative cytotoxicity in myotube derived hydrogen peroxide	3
Can bone mass measured via bioelectrical impedance analysis be used to diagnose sarcopenia?	3
Combined effects of granulocyte and monocyte adsorption apheresis and corticosteroids on ulcerative colitis	3
Induction of mucosal healing by intensive granulocyte/monocyte adsorptive apheresis (GMA) without use of corticosteroids in patients with ulcerative colitis: long-term remission maintenance after indu	3
Impact of oligomeric enteral nutrition with low-molecular-weight whey peptides on diarrhea in critical care nutrition	3
Reducing early pregnancy loss with vitamin D<sub>3</sub>: an analysis of serum 1,25-(OH)D<sub>3</sub> modulation and miscarriage risk	3
Association between dyspeptic symptoms and endoscopic findings based on the Kyoto classification of gastritis in Japanese male	3
<i>Streptococcus thermophilus</i> extends lifespan through activation of DAF-16-mediated antioxidant pathway in <i>Caenorhabditis elegans</i>	3
Fermented rice bran supplementation ameliorates obesity via gut microbiota and metabolism modification in female mice	3
Induction of <i>MYCN</i>-amplified neuroblastoma differentiation through NMYC suppression using PPAR-γ antagonist	3
Relationships between body mass index and constipation, gastroesophageal reflux disease, stool forms based on the Bristol Stool Form Scale, and education level: results from an internet survey in Japa	3
Interaction between inorganic phosphate concentration and glucose metabolism in mild refeeding syndrome model	3
The alteration of serum bile acid profile among traumatic brain injury patients: a small-scale prospective study	3
Confirmation of efficacy, elucidation of mechanism, and new search for indications of radon therapy	3

Association of alcohol intake and female gender with high expression of TMPRSS2 in tongue as potential risk for SARS-CoV-2 infection	3
Combined fructose and sucrose consumption from an early age aggravates cardiac oxidative damage and causes a dilated cardiomyopathy in ‍SHR rats	3
A newly developed solution for the preservation of short-chain fatty acids, bile acids, and microbiota in fecal specimens	2
Association of urinary 8-hydroxydeoxyguanosine level with arteriosclerosis-related factors in ‍healthy, urban residents aged ≥50 years in ‍Japan	2
Ethanol enhances selenoprotein P expression via ERK-FoxO3a axis in HepG2 cells	2
Oral supplementation of a cell preparation of <i>Enterococcus faecalis</i> strain EC-12 stimulates superoxide dismutase production in the livers of healthy and arthritis-induced mice	2
Protective effects of 2-aminoethylthiosulfuric acid and structurally analogous organosulfur compounds against ionizing radiation	2
Effect of omega-3 fatty acids on sleep: a systematic review and meta-analysis of randomized controlled trials	2
Reciprocal regulation of protein arginine deiminase 2 and 4 expression in the colonic mucosa of ulcerative colitis	2
Linear association between aging and decreased blood thiol antioxidant activity in patients with cataract	2
Redox state as assessed using the measurement of human non-mercaptalbumin in embryo culture media is associated with successful embryo development in human <i>in vitro</i> fertilization	2
Effects of ergothioneine on oxidative DNA damage and immune response induced by circadian rhythm disturbance in mice	2
Characterized factors of subjects who were first time diagnosed as hyperglycemia more than 126 ‍mg/dl during annual or biannual medical checkups: a case-control study in Japan	2
Intensive, prolonged exercise seemingly causes gut dysbiosis in female endurance runners	2
LC/MS/MS detection of uric acid oxidation metabolites to evaluate reactive oxygen and nitrogen species <i>in vivo</i> with application to pseudo-inflammation	2
Comparison of the oxidative profiles before and after revascularization in peripheral arterial disease: a pilot study	2
Introduction to serial reviews: Copper biology in health and disease	2
A pathological link between dysregulated copper binding in Cu/Zn-superoxide dismutase and amyotrophic lateral sclerosis	2
Theaflavins decrease skeletal muscle wasting in disuse atrophy induced by hindlimb suspension in mice	2
Innovative novel candy made from a low-solubility amorphous material promotes saliva secretion: a randomized, double-blind, placebo-controlled crossover comparative trial	2
D-Cysteine supplementation partially protects against ferroptosis induced by xCT dysfunction via increasing the availability of glutathione	2
Balance of the prooxidant and antioxidant system is associated with mortality in critically ill patients	2
Metabolomics analysis of amino acid and fatty acids in colorectal cancer patients based on tandem mass spectrometry	2
Role of gut microbiota in inflammatory bowel disease pathogenesis	2
Plasma-activated medium exerts tumor-specific inhibitory effect on hepatocellular carcinoma via disruption of the salvage pathway	2
Method for detecting CoQ10 incorporation in the mitochondrial respiratory chain supercomplex	2
Short-term intake of delta-tocotrienol on lipid profiles in healthy subjects	2
Nobiletin, a polymethoxylated flavonoid from citrus, enhances IL-4 production in DO11.10 mice via antigen-presenting cells	2
Sebacic acid, a royal jelly-containing fatty acid, decreases LPS-induced IL-6 mRNA expression in ‍differentiated human THP-1 macrophage-like cells	2
Serum titer of neutralizing antibodies after COVID-19 vaccination in Japanese patients with inflammatory bowel disease	2
The fetal gastrointestinal tract is exposed to melatonin and superoxide dismutase rich amniotic fluid throughout prenatal development	2
Slowly progressive cell death induced by GPx4-deficiency occurs via MEK1/ERK2 activation as a downstream signal after iron-independent lipid peroxidation	2
Pharmacokinetics and effect of maslinic acid with physical exercise on grip strength and trunk muscle mass in healthy Japanese individuals	2
Increased salt intake is associated with diabetes and characteristic dietary habits: a community-based cross-sectional study in Japan	2
Singlet oxygen from endoperoxide initiates an intracellular reactive oxygen species release in HaCaT keratinocytes	2
Crosstalk of copper and zinc in the pathogenesis of vascular dementia	2
Regulation of type I IFN responses by deubiquitinating enzyme A in inflammatory bowel diseases	2
Resveratrol is converted to the ring portion of coenzyme Q10 and raises intracellular coenzyme Q10 levels in HepG2 cell	2
<i>Trans</i>-resveratrol reduced hepatic oxidative stress in an animal model without inducing an ‍upregulation of nuclear factor erythroid 2-‍related factor 2	1
Fat-free oral nutritional supplements for patients after acute illness: a prospective observational study	1
Transferrin, insulin, and progesterone modulate intracellular concentrations of coenzyme Q and cholesterol, products of the mevalonate pathway, in undifferentiated PC12 cells	1
Cellular level of coenzyme Q increases with neuronal differentiation, playing an important role in neural elongations	1
Twendee X, a mixed antioxidant supplement, improves cognitive function, coordination, and neurotrophic factor expression in long-term vitamin E-deficient mice	1
Single oral administration of quercetin glycosides prevented acute hyperglycemia by ‍promoting GLUT4 translocation in skeletal muscles through the activation of AMPK in mice	1
Oleic acid to stearic acid ratio might be a potential marker for insulin resistance in non-obese Japanese	1
Optimizing vitamin supplementation via reference interval update of vitamins A, E, B1, and B6 using HPLC	1
Reactive oxygen species induced by indomethacin enhance accumulation of heme ‍carrier protein 1 and hematoporphyrin accumulation <i>in vitro</i> and <i>in vivo</i> in a brain t	1
Orally ingested ubiquinol-10 or ubiquinone-10 reaches the intestinal tract and is absorbed by the small intestine of mice mostly in its original form	1
Mitochondrial stress and glycoxidation increase with decreased kidney function	1
Intragastric bacterial infection and endoscopic findings in <i>Helicobacter pylori</i>-negative patients	1
CREB1 regulates RECQL4 to inhibit mitophagy and promote esophageal cancer metastasis	1
5-<i>N</i>-Carboxyimino-6-aminopyrimidine-2,4(3<i>H</i>)-dione, a novel indicator for hypochlorite formation	1
Effects of luseogliflozin treatment on hyperglycemia-induced muscle atrophy in rats	1
Vitamin D insufficiency and disease risk in the elderly	1
Assessment of exposure and DNA damage from second-hand smoke using potential biomarker in urine: cigarettes and heated tobacco products	1
Coenzyme Q10 levels increase with embryonic development in medaka	1
Identification of miRNAs Associated with Eosinophilic Esophagitis Shown by Esophageal Mucosal Biopsy Results of Japanese Patients	1
Protective effects of dried mature <i>Citrus unshiu</i> peel (Chenpi) and hesperidin on aspirin-induced oxidative damage	1
Humoral and cellular factors inhibit phosphate-induced vascular calcification during the growth period	1
The significance of CDT1 expression in non-cancerous and cancerous liver in cases with hepatocellular carcinoma	1
Dietary intervention of prebiotic partially hydrolyzed guar gum improves skin viscoelasticity, stratum corneum hydration, and ‍reduction of trans-epidermal water loss: a ‍randomized, double-blind, and	1
Efficacy evaluation of upper gastrointestinal endoscopy screening for secondary prevention of gastric cancer using the standardized detection ratio during a medical check-up in ‍Japan	1
High-intensity exercise impairs intestinal barrier function by generating oxidative stress	1
A mixed antioxidant supplement improves cognitive function, and coordination in aged mice	1
Soy isoflavone genistein attenuates the efficacy of immune checkpoint therapy in C57BL/6 mice inoculated with B16F1 melanoma and a high PD-‍L1 expression level reflects tumor resistance	1
Effects of reaction environments on radical-scavenging mechanisms of ascorbic acid	1
Gut dysbiosis induced by a high-salt diet aggravates atherosclerosis by increasing the absorption of saturated fatty acids in ApoE-deficient mice	1
State of anxiety may be associated with exocrine pancreatic insufficiency in functional dyspepsia patients with pancreatic enzyme abnormalities	1
Iron as spirit of life to share under monopoly	1
NEK7 inhibition attenuates Aβ<sub>42</sub>-induced cognitive impairment by regulating TLR4/NF-κB and the NLRP3 inflammasome in mice	1
Zinc supplementation with polaprezinc was associated with improvements in albumin, prothrombin time activity, and hemoglobin in ‍chronic liver disease	1
Increased expression of ELOVL7 contributes to production of inflammatory cytokines in THP-1 cell-derived M1-like macrophages	1
Stimulatory effects of collagen production induced by coenzyme Q<sub>10</sub> in cultured skin fibroblasts	1
Oxidative stress induces tau hyperphosphorylation via MARK activation in neuroblastoma N1E-115 cells	1
Single-cell analysis reveals islet autoantigen’s immune activation in type 1 diabetes patients	1
Availability of dietary secoisolariciresinol diglucoside on borderline blood cholesterol level in men: a randomized, parallel, controlled, double-blinded clinical trial	1
Miso, fermented soybean paste, suppresses high-fat/high-sucrose diet-induced muscle atrophy in mice	1
Dietary antioxidants and flavonoids intake, and their association with inflammation and oxidative stress parameters in asthmatic women: a case-control study	1
Erratum	1