Xenotransplantation

Papers
(The TQCC of Xenotransplantation is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-09-01 to 2024-09-01.)
ArticleCitations
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months77
Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies42
Decellularized xenografts in regenerative medicine: From processing to clinical application31
Genetically engineered pig kidney transplantation in a brain‐dead human subject29
Factors influencing attitudes toward xenotransplantation clinical trials: A report of focus group studies27
Physiological aspects of pig kidney xenotransplantation and implications for management following transplant24
The first clinical pig heart transplant: Was IVIg or pig cytomegalovirus detrimental to the outcome?24
Growth hormone receptor knockout: Relevance to xenotransplantation23
Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig‐to‐baboon xenotransplantation23
Recent progress and remaining hurdles toward clinical xenotransplantation22
Evidence suggesting that deletion of expression of N‐glycolylneuraminic acid (Neu5Gc) in the organ‐source pig is associated with increased antibody‐mediated rejection of kidney transplants in baboons22
Racial differences in attitudes to clinical pig organ Xenotransplantation20
The porcine cytomegalovirus (PCMV) will not stop xenotransplantation19
Long‐term porcine islet graft survival in diabetic non‐human primates treated with clinically available immunosuppressants16
Commentary on achievement of first life‐saving xenoheart transplant16
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?15
Solid‐phase silica‐based extraction leads to underestimation of residual DNA in decellularized tissues15
Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboons15
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models15
Evidence that sensitization to triple‐knockout pig cells will not be detrimental to subsequent allotransplantation13
Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons13
A perspective on the potential detrimental role of inflammation in pig orthotopic heart xenotransplantation12
The attitudes of religious group leaders towards xenotransplantation: A focus group study12
The problem of the “4th xenoantigen” after pig organ transplantation in non‐human primates may be overcome by expression of human “protective” proteins12
Initial evidence that blockade of the CD40/CD154 costimulation pathway alone is sufficient as maintenance therapy in xenotransplantation11
PCR and peptide based PCMV detection in pig – development and application of a combined testing procedure differentiating newly from latent infected pigs11
Xenotransplantation of tannic acid‐encapsulated neonatal porcine islets decreases proinflammatory innate immune responses11
World first pig‐to‐human cardiac xenotransplantation11
Experimental approach to nasal septal cartilage regeneration with adipose tissue‐derived stem cells and decellularized porcine septal cartilage11
Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood11
Scientific and psychosocial ethical considerations for initial clinical trials of kidney xenotransplantation11
The 2021 IXA Keith Reemtsma Lecture: Moving xenotransplantation to the clinic10
Immunological selection and monitoring of patients undergoing pig kidney transplantation10
Knowledge of and attitude toward xenotransplantation among medical students in China: A cross‐sectional study10
Potential roles of mesenchymal stromal cells in islet allo‐ and xenotransplantation for type 1 diabetes mellitus10
Further information on possible animal sources for human COVID‐1910
Xenotransplantation: A historical–ethical account of viewpoints9
Multipotent mesenchymal stromal cells derived from porcine exocrine pancreas improve insulin secretion from juvenile porcine islet cell clusters9
Assessment of glomerular filtration and tubular secretion in baboons with life‐supporting pig kidney grafts9
The first clinical trial—Kidney or heart?9
Coagulation, inflammation, and CD46 transgene expression in neonatal porcine islet xenotransplantation9
Attitudes of patients with renal disease on xenotransplantation: A systematic review9
Xenotransplantation of neonatal porcine bone marrow‐derived mesenchymal stem cells improves murine hind limb ischemia through lymphangiogenesis and angiogenesis8
Deep anterior lamellar keratoplasty with cross‐linked acellular porcine corneal stroma to manage fungal keratitis8
Xenotransplantation of neonatal porcine bone marrow–derived mesenchymal stem cells improves diabetic wound healing by promoting angiogenesis and lymphangiogenesis8
The case for the therapeutic use of mechanistic/mammalian target of rapamycin (mTOR) inhibitors in xenotransplantation8
The road to the first FDA‐approved genetically engineered pig heart transplantation into human7
Pig‐to‐human kidney transplantation using brain‐dead donors as recipients: One giant leap, or only one small step for transplantkind?7
Early testing of porcine organ xenotransplantation products in humans: Microbial safety as illustrated for porcine cytomegalovirus7
Invited commentary: Initial reflections on the world's first clinical genetically‐engineered pig heart transplant7
Generating liver using blastocyst complementation: Opportunities and challenges6
The effects of necrostatin‐1 on the in vitro development and function of young porcine islets over 14‐day prolonged tissue culture6
Current state of clinical trials on xenograft6
Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation6
Anti‐thymoglobulin induction improves neonatal porcine xenoislet engraftment and survival6
Extracellular histones and xenotransplantation6
Lebanese medical students’ knowledge on and attitude toward xenotransplantation and its ethical issues: A cross‐sectional study6
Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans6
Mixed xenogeneic porcine chimerism tolerizes human anti‐pig natural antibody‐producing cells in a humanized mouse model5
Knock‐out of N‐glycolylneuraminic acid attenuates antibody‐mediated rejection in xenogenically perfused porcine lungs5
Dot blots of solubilized extracellular matrix allow quantification of human antibodies bound to epitopes present in decellularized porcine pulmonary heart valves5
Generation of glycans depleted decellularized porcine pericardium, using digestive enzymatic supplements and enzymatic mixtures for food industry5
Comparison of islet isolation result and clinical applicability according to GMP‐grade collagenase enzyme blend in adult porcine islet isolation and culture5
Third update on possible animal sources for human COVID‐195
Opinions of nursing and theology faculty students on Xenotransplantation5
First transplantation of a pig heart from a multiple gene‐modified donor, porcine cytomegalovirus/roseolovirus, and antiviral drugs5
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