OOIR: Observatory of International Research

Papers

(The median citation count of Xenotransplantation is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Meeting report: Xenotransplantation Development Conference in Neijiang, China	83
Deceased humans and living pigs as sources of kidneys for clinical transplantation—Can they be compared?	31
Bridging Therapies—Ex Vivo Liver Xenoperfusion and the Role of Machine Perfusion: An Update	29
Comparison of islet isolation result and clinical applicability according to GMP‐grade collagenase enzyme blend in adult porcine islet isolation and culture	28
Scientific and psychosocial ethical considerations for initial clinical trials of kidney xenotransplantation	25
Bioinformatic analysis as a first step to predict the compatibility of hematopoiesis and immune system genes between humans and pigs	24
Issue Information	24
Issue Information	22
	22
Invited commentary	19
Clinical cardiac xenotransplantation first in the clinical arena	16
Cover image	15
A compositional analysis of native and decellularized porcine nasal septum cartilage	15
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models	14
	13
Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques	12
Cover image	12
	12
Current state of clinical trials on xenograft	11
Hendrik Jan (Henk) Schuurman, MSc, PhD (1950–2024): In Memoriam	11
Transgenic pigs expressing near infrared fluorescent protein—A novel tool for noninvasive imaging of islet xenotransplants	11
Issue Information	11
Abstracts	11
	10
Development of a panel for detection of pathogens in xenotransplantation donor pigs	10

Incidence of serum antibodies to xenoantigens on triple‐knockout pig cells in different human groups	10
In defense of xenotransplantation research: Because of, not in spite of, animal welfare concerns	10
In Memoriam: Sir Roy Calne, FRCS, FRS, 1930–2024	9
Anti‐pig antibodies in swine veterinarian serum: Implications for clinical xenotransplantation	9
Knock‐out of N‐glycolylneuraminic acid attenuates antibody‐mediated rejection in xenogenically perfused porcine lungs	9
The porcine cytomegalovirus (PCMV) will not stop xenotransplantation	9
Increased human complement pathway regulatory protein gene dose is associated with increased endothelial expression and prolonged survival during ex‐vivo perfusion of GTKO pig lungs with human blood	8
Commentary on achievement of first life‐saving xenoheart transplant	8
Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs	8
Systemic inflammation in xenograft recipients (SIXR) or undetected PCMV/PRV transmission?	7
Comparative Inhibitory Effects of Tacrolimus, Cyclosporine, and Rapamycin on Human Anti‐Pig Xenogeneic Mixed Lymphocyte Reactions	7
Xenotransplantation of tannic acid‐encapsulated neonatal porcine islets decreases proinflammatory innate immune responses	7
An intrinsic link to an extrinsic cause of cardiac xenograft growth after xenotransplantation	7
Systemic inflammation in the xenotransplant recipient (SIXR) can occur in the absence of pCMV infection	6
A perspective on the potential detrimental role of inflammation in pig orthotopic heart xenotransplantation	6
Close contacts of xenograft recipients: Ethical considerations due to risk of xenozoonosis	6
First transplantation of a pig heart from a multiple gene‐modified donor, porcine cytomegalovirus/roseolovirus, and antiviral drugs	6
The Young Investigator Committee of the International Xenotransplantation Association—Perspective of advancements in the field in 2023	6
Transthoracic echocardiography is a simple tool for size matching in cardiac xenotransplantation	5
Barriers toward xenotransplantation in Arab World	5
Xenotransplantation Literature Update January/February 2021	5
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months	5
Invited commentary on “Deep Anterior lamellar keratoplasty with Cross‐linked Acellular Porcine Corneal Stroma to Manage Fungal Keratitis”	5
Antibodies against hyaluronan oligosaccharides in xenotransplantation	5
Issue Information	4
Semi‐automated digital quantification of cellular infiltrates for in vivo evaluation of transplanted islets of Langerhans encapsulated with bioactive materials	4
Anti‐thymoglobulin induction improves neonatal porcine xenoislet engraftment and survival	4
Porcine cytomegalovirus: A very unwelcome stowaway	4
Porcine embryonic stem cells: An alternative solution for the shortage of human islets to treat type 1 diabetes?	4
Potential roles of mesenchymal stromal cells in islet allo‐ and xenotransplantation for type 1 diabetes mellitus	4
Distinct Pro‐Inflammatory Species‐Specific Transcriptional Changes in Human T Cells Following Pig Xenogeneic Stimulation	4
What is the clinical relevance of deviant serum calcium and phosphate levels after pig‐to‐primate kidney xenotransplantation?	4
	4
hEPCR.hTBM.hCD47.hHO‐1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood	4
Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs	4
ECG Features in Orthotopic Cardiac Xenotransplantation: Comparisons With Published Literature	4
Antibody‐mediated rejection in xenotransplantation: Can it be prevented or reversed?	4
Agnès Marie Azimzadeh, Ph.D – “In Memoriam”	4
	3
	3
Limited environmental stability of infectious porcine endogenous retrovirus type C; Usage of reverse transcriptase in combination with viral RNA as markers for infectious virus	3
Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans	3
The 2021 IXA Keith Reemtsma Lecture: Moving xenotransplantation to the clinic	3
Issue Information	3
Issue Information	3
Asking the Right Questions: Larry Faucette's Journey Through Xenotransplant	3
The impact of IdeS (imlifidase) on allo‐specific, xeno‐reactive, and protective antibodies in a sensitized rhesus macaque model	3
Human erythrocyte fragmentation during ex‐vivo pig organ perfusion	3
	3
Issue Information	3

Heterogenous expression of endocrine and progenitor cells within the neonatal porcine pancreatic lobes–Implications for neonatal porcine islet xenotransplantation	3
	2
He reshaped the forefront of xenotransplantation: Agustin Pasqual Dalmasso (1933–2021)	2
Attitudes of patients with renal disease on xenotransplantation: A systematic review	2
Historic progress in xenotransplantation with successful transplantation of genetically‐edited pig kidneys into living recipients	2
Anti–Non‐Gal Antibodies Against Porcine Protein Antigens as Barrier to Long‐Term Grafting of Xenografts in Humans	2
Xenotransplantation of neonatal porcine bone marrow‐derived mesenchymal stem cells improves murine hind limb ischemia through lymphangiogenesis and angiogenesis	2
Intensive Surveillance of Porcine‐Rhesus Kidney Xenotransplant Using Different Ultrasound Techniques	2
Late graft failure of pig‐to‐rhesus renal xenografts has features of glomerulopathy and recipients have anti‐swine leukocyte antigen class I and class II antibodies	2
Evidence suggesting that deletion of expression of N‐glycolylneuraminic acid (Neu5Gc) in the organ‐source pig is associated with increased antibody‐mediated rejection of kidney transplants in baboons	2
	2
Xenotransplantation literature update March 2023–November 2023	2
Generation and transplantation of hepatocytes‐like cells using human origin hepatogenic serum for acute liver injury treatment	2
Issue Information	2
Issue Information	2
Glycocalyx dynamics and the inflammatory response of genetically modified porcine endothelial cells	2
Opinions of nursing and theology faculty students on Xenotransplantation	2
An IgM Cleaving Enzyme for Clearance of Anti‐Pig Xenoreactive Antibodies in a Nonhuman Primate Model	2
Characterisation of transgenic pigs expressing a human T cell‐depleting anti‐CD2 monoclonal antibody	2
Multipotent mesenchymal stromal cells derived from porcine exocrine pancreas improve insulin secretion from juvenile porcine islet cell clusters	2
Large‐Scale Formation and Long‐Term Culture of Hepatocyte Organoids From Streamlined In Vivo Genome‐Edited GGTA1^−/− Pigs for Bioartificial Liver Applications	2
Two‐day Static Cold Preservation of α1,3‐Galactosyltransferase Knockout Kidney Grafts Before Simulated Xenotransplantation	2
Molecular incompatibility between pig CD200 and human CD200 receptor in in vitro xenogeneic immune responses	2
Xenotransplantation of neonatal porcine bone marrow–derived mesenchymal stem cells improves diabetic wound healing by promoting angiogenesis and lymphangiogenesis	2
Lebanese medical students’ knowledge on and attitude toward xenotransplantation and its ethical issues: A cross‐sectional study	1
	1
PCR and peptide based PCMV detection in pig – development and application of a combined testing procedure differentiating newly from latent infected pigs	1
A study of knowledge and acceptance of kidney xenotransplantation among Chinese kidney transplant recipients and candidates	1
Xenotransplantation: A historical–ethical account of viewpoints	1
SARS‐CoV‐2 does not infect pigs, but this has to be verified regularly	1
Novel factors potentially initiating acute antibody‐mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen	1
Alteration of γδ T cell subsets in non‐human primates transplanted with GGTA1 gene‐deficient porcine blood vessels	1
A murine groin site cardiac transplantation model—applicable tool for studying roles of peripheral lymph nodes in transplantation	1
	1
An ethical algorithm for xenotransplantation? Further transparency and clarity needed	1
Development and characterization of islet‐derived mesenchymal stem cells from clinical grade neonatal porcine cryopreserved islets	1
In Memoriam – Guy Alexandre (1934–2024)	1
Xenotransplantation clinical trials: Should patients with diminished capacity be permitted to enroll?	1
Factors influencing attitudes toward xenotransplantation clinical trials: A report of focus group studies	1
Preservation of Cardiac Xenografts in a Model of Infant Human Cardiac Transplantation	1
Evaluation of knowledge, attitude, and awareness of liver transplant patients toward xenotransplantation	1
	1
Issue Information	1
Open invitation to contribute ideas to a multifaceted approach to ethics in xenotransplantation	1
	1
Coagulation, inflammation, and CD46 transgene expression in neonatal porcine islet xenotransplantation	1
Emergence of novel circoviruses in humans and pigs and their possible importance for xenotransplantation and blood transfusions	1
Issue Information	1
Non‐Classical Swine Leukocyte Antigens SLA‐6, ‐7, and ‐8, Are Xenoantigens for Some Waitlisted Patients	1
Xenoreactive antibodies in α‐granules of human platelets bind pig liver endothelial cells	1
Generation of glycans depleted decellularized porcine pericardium, using digestive enzymatic supplements and enzymatic mixtures for food industry	1
Hemodynamics in pig‐to‐baboon heterotopic thoracic cardiac xenotransplantation: Recovery from perioperative cardiac xenograft dysfunction and impairment by cardiac overgrowth	1
The evidence of a macrophage barrier in the xenotransplantation of human hematopoietic stem cells to severely immunodeficient rats	1
Immunological selection and monitoring of patients undergoing pig kidney transplantation	1
Early testing of porcine organ xenotransplantation products in humans: Microbial safety as illustrated for porcine cytomegalovirus	1
In vivo induction of regulatory T cells by anti‐CD45RB antibody causes transferable tolerance to discordant human xenogenic islets	1
Pancreas preservation with amphotericin B deteriorates islet yield for porcine islet isolation	1
Recent progress and remaining hurdles toward clinical xenotransplantation	1