Xenotransplantation

Article	Citations
	38
Systemic inflammation in the xenotransplant recipient (SIXR) can occur in the absence of pCMV infection	32
Bioinformatic analysis as a first step to predict the compatibility of hematopoiesis and immune system genes between humans and pigs	22
Hendrik Jan (Henk) Schuurman, MSc, PhD (1950–2024): In Memoriam	22
Transthoracic echocardiography is a simple tool for size matching in cardiac xenotransplantation	21
Xenotransplantation Literature Update July–December 2024	20
Impact of COVID‐19 Vaccination and Infection on Anti‐Triple‐Knockout (TKO) Pig Antibody Production: A Study in Patients With End‐Stage Liver Disease and Liver Transplant Recipients	20
Anti‐pig antibodies in swine veterinarian serum: Implications for clinical xenotransplantation	19
First transplantation of a pig heart from a multiple gene‐modified donor, porcine cytomegalovirus/roseolovirus, and antiviral drugs	19
Anatomical and Physiological Considerations for Pig Cardiac Xenotransplantation	16
A Review of Studies of Perfusion Storage of Pig Kidneys and Their Relevance to Clinical Xenotransplantation	15
RETRACTION: An IgM Cleaving Enzyme for Clearance of Anti‐Pig Xenoreactive Antibodies in a Nonhuman Primate Model	14
ECG Features in Orthotopic Cardiac Xenotransplantation: Comparisons With Published Literature	14
Issue Information	13
Complement Inhibition in Xenotransplantation–Where Should the Complement Cascade be Inhibited?	13
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Heterogenous expression of endocrine and progenitor cells within the neonatal porcine pancreatic lobes–Implications for neonatal porcine islet xenotransplantation	13
Modified CD40L‐Activated B‐Cell Proliferation Model for Validating the Suppressive Activity of CD40‐CD154 Pathway Inhibitors	12
He reshaped the forefront of xenotransplantation: Agustin Pasqual Dalmasso (1933–2021)	12
An ethical algorithm for xenotransplantation? Further transparency and clarity needed	12
COVER IMAGE	11
The case for the therapeutic use of mechanistic/mammalian target of rapamycin (mTOR) inhibitors in xenotransplantation	11
Xenotransplantation Literature Update December 2023–June 2024	11
Xenoreactive antibodies in α‐granules of human platelets bind pig liver endothelial cells	11
Religion and Attitudes Toward Xenotransplantation: Results of a Nationwide Survey in the United States	11

Xenotransplantation: A historical–ethical account of viewpoints	11
Assessment of Porcine Endogenous Retrovirus Infectivity to Human Cells Using Flowcytometric Isolation After Co‐Culture	11
Xenotransplantation in the Age of Genome Editing: Results From the Expert Report for the Federal Ethics Committee on Nonhuman Biotechnology With a Special Focus on Animal Ethics	10
Xenotransplantation of pig islet cells: Potential adverse impact of virus infections on their functionality and insulin production	10
Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain	10
Overcoming perioperative inflammation as a hurdle for successful preclinical orthotopic cardiac xenogeneic transplantations – particular in regard of the mandatory use of heart‐lung machines	9
Issue Information	9
Evaluation of Complement‐Dependent Cytotoxicity Assays for Gene‐Edited Pig‐to‐Human Xenotransplantation	9
Global Research Trends and Current Status of Xenotransplantation: A Bibliometric Analysis	8
Observations on hydronephrosis after pig kidney transplantation in baboons	8
Clinical Pig Kidney Xenotransplantation Rewrites the Rules of Renal Graft Rejection	8
Announcement	8
Ethical Analysis of Voluntariness in Pig Kidney Xenotransplant First‐in‐Human Clinical Trials	8
Defect in Sensing Human Thrombin by Porcine Endothelial Protease‐Activated Receptor‐1: Molecular Incompatibility Between Porcine PAR‐1 and Human Thrombin	8
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Functional Xenogeneic Liver Support in a Living Human: Promise, Lessons, and Next Steps	7
Vatican Reaffirms Moral Permissibility of Xenotransplantation	7
Genetic diversity, growth and heart function of Auckland Island pigs, a potential source for organ xenotransplantation	7
Rural Transplant Disparities and Xenotransplantation: Scaling Is Not Enough	7
Exploring attitudes toward xenotransplantation: A scoping review of healthcare workers, healthcare students, and kidney patients	7
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Donor‐Derived Cell‐Free DNA (dd‐cfDNA) as an Early Noninvasive Biomarker of Graft Injury in Pig‐to‐Monkey Islet Xenotransplantation	7
Comparative Inhibitory Effects of Tacrolimus, Cyclosporine, and Rapamycin on Human Anti‐Pig Xenogeneic Mixed Lymphocyte Reactions	6
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Pilot Survey of Attitudes Toward Xenotransplantation Among Nursing Students in London, UK	6
Issue Information	6
Porcine Cytomegalovirus/Porcine Roseolovirus (PCMV/PRV) and Antiviral Drugs	6
International Xenotransplantation Association (IXA) Position Paper on the History, Current Status, and Regulation of Xenotransplantation	6
Xenotransplantation, Ethics, and Pediatric Decedent Studies	6
Antibody‐mediated rejection in xenotransplantation: Can it be prevented or reversed?	6
Historic progress in xenotransplantation with successful transplantation of genetically‐edited pig kidneys into living recipients	6
A compositional analysis of native and decellularized porcine nasal septum cartilage	6
Antibodies against hyaluronan oligosaccharides in xenotransplantation	6
The Emergence of the Asian Xenotransplantation Association: Regional Collaboration in a Rapidly Evolving Field	6
Asking the Right Questions: Larry Faucette's Journey Through Xenotransplant	6
Human CD64 Alleviates Antibody‐Mediated Rejection in Xenotransplantation	5
Humoral Barrier to Preclinical and Clinical Xenotransplantation	5
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RETRACTION: Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication with Preserved Bioactivity: A Comparative Evaluation	5
Alteration of γδ T cell subsets in non‐human primates transplanted with GGTA1 gene‐deficient porcine blood vessels	5
Two‐day Static Cold Preservation of α1,3‐Galactosyltransferase Knockout Kidney Grafts Before Simulated Xenotransplantation	5
Harmonizing International Regulatory Standards for Porcine Endogenous Retrovirus (PERV) Screening in Genetically Modified Porcine Donors for First‐in‐Human Pancreatic Islet Xenotransplantation	5
The impact of IdeS (imlifidase) on allo‐specific, xeno‐reactive, and protective antibodies in a sensitized rhesus macaque model	5
Governmental Questionnaire Survey on Adolescent and Young Adults’ Views on the Clinical Application of Xenotransplantation	5
In Memoriam – Guy Alexandre (1934–2024)	5
Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans	5
Large‐Scale Formation and Long‐Term Culture of Hepatocyte Organoids From Streamlined In Vivo Genome‐Edited GGTA1−/− Pigs for Bioartificial Liver Applications	5
In vivo induction of regulatory T cells by anti‐CD45RB antibody causes transferable tolerance to discordant human xenogenic islets	5
Sex Differences in Maturation and Function of Neonatal Porcine Islets Upon Transplantation in Mice	4
Xenotransplantation clinical trials: Should patients with diminished capacity be permitted to enroll?	4

Xenotransplantation Literature Update: July–December 2025	4
How to Detect Porcine Endogenous Retrovirus (PERV) Infections in Patients After Transplantation of Pig Organs	4
Use of Brain Death Recipients in Xenotransplantation: A Double‐Edged Sword	4
The birth of Dolly and xenotransplantation 25 years on	4
SARS‐CoV‐2 does not infect pigs, but this has to be verified regularly	4
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Realistic Prospects of Xenotransplantation in Japan: Specific Regulations for Clinical Application	4
Issue Information	4
Removal of Porcine Endogenous Retroviruses in Decellularized Liver Bioscaffolds	4
Treatment of Presumptive Rejection After Orthotopic Pig‐to‐Baboon Cardiac Xenotransplantation	4
The International Human Xenotransplantation Inventory: Current Data and Future Directions	4
Renin‐Angiotensin‐Aldosterone System (RAAS) in Pig‐to‐Baboon Kidney Xenotransplantation—Relevance to Clinical Pig Kidney Xenotransplantation	4
RETRACTION: Evaluation of Complement‐Dependent Cytotoxicity Assays for Gene‐Edited Pig‐to‐Human Xenotransplantation	4
International Xenotransplantation Association (IXA) Position Paper on Kidney Xenotransplantation	3
Advances in Subclinical and Clinical Trials and Immunosuppressive Therapies in Xenotransplantation	3
Will Pig Organ Xenotransplantation in Patients Complicate the Use of Commonly Administered Drugs?	3
Author List	3
In Vitro Evaluation of Basiliximab as an Induction Therapy for Xenotransplantation	3
“Will I Still be Myself?” Opposition to Xenotransplantation Among Chinese Kidney Transplant Candidates: A Qualitative Study	3
Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication With Preserved Bioactivity: A Comparative Evaluation	3
The porcine cytomegalovirus (PCMV) will not stop xenotransplantation	3
Issue Information	3
Pig‐to‐human kidney transplantation using brain‐dead donors as recipients: One giant leap, or only one small step for transplantkind?	3
Xenotransplantation at 30 years – A personal reminiscence and some thoughts for the future	3
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Patient informed consent for a clinical trial of gene‐edited pig kidney transplantation: A representative consent form	3
Knock‐out of N‐glycolylneuraminic acid attenuates antibody‐mediated rejection in xenogenically perfused porcine lungs	3
Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs	3
CMAH‐Targeted Knock‐In of Inducible Heme Oxygenase‐1 and Constitutive CD47 in GGTA1‐Knockout Pigs for Xenotransplantation	3
In Memoriam: Sir Roy Calne, FRCS, FRS, 1930–2024	3
Public Attitudes Toward Xenotransplantation in South Korea: A 2023 Survey Study	3
Long‐term control of diabetes by tofacitinib‐based immunosuppressive regimen after allo islet transplantation in diabetic rhesus monkeys that rejected previously transplanted porcine islets	3
Xenotransplantation and Disability Contraindications to Pediatric Heart Transplantation: Are We at the Horizon of Organ Transplantation for any Person That May Benefit?	3
Which Platform of SARS‐CoV‐2 Vaccines Should be Used for Xenotransplant Recipients?	3
Bridging Therapies—Ex Vivo Liver Xenoperfusion and the Role of Machine Perfusion: An Update	3
Periodic Trajectories of the Plasma Metabolome in a Pig‐to‐Non‐Human Primate Cardiac Xenograft Model	3
Cellular Landscapes of Different Gene‐Edited Pig Hearts Associated With Cardiac Xenotransplantation	3
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Liver Xenotransplantation: Ethical and Societal Implications	2
Non‐Classical Swine Leukocyte Antigens SLA‐6, ‐7, and ‐8, Are Xenoantigens for Some Waitlisted Patients	2
An IgM Cleaving Enzyme for Clearance of Anti‐Pig Xenoreactive Antibodies in a Nonhuman Primate Model	2
Molecular incompatibility between pig CD200 and human CD200 receptor in in vitro xenogeneic immune responses	2
Abstracts	2
Evaluation of knowledge, attitude, and awareness of liver transplant patients toward xenotransplantation	2
Novel factors potentially initiating acute antibody‐mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen	2
Xenotransplantation in China: Past, Present, and Future	2
A murine groin site cardiac transplantation model—applicable tool for studying roles of peripheral lymph nodes in transplantation	2
Issue Information	2
Development and characterization of islet‐derived mesenchymal stem cells from clinical grade neonatal porcine cryopreserved islets	2
Xenotransplantation literature update March 2023–November 2023	2
Quantitative Proteomic Analysis of Cardiac Xenograft Failure in a Pig‐to‐Non‐Human Primate Model Identifies NF‐κB as a Critical Immunomodulatory Target	2
Mapping the Evolution of Solid Organ Xenotransplantation Research:A Systematic Review	2
Xenotransplantation Literature Update: January–June 2025	2
Integrated Multi‐Omics Analysis of Coagulation Dysregulation and Immune Pathway Alterations in 10‐Gene Pig‐to‐Monkey Liver Xenotransplantation: A Case Report	2
Anti–Non‐Gal Antibodies Against Porcine Protein Antigens as Barrier to Long‐Term Grafting of Xenografts in Humans	2
Issue Information	2
Mathieu Jaboulay's (1860–1913) contribution to xenotransplantation	1
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?	1
Lessons learned from the first cardiac xenotransplant in a consciously consenting human: Psychiatric considerations and the impact of media exposure	1
Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs	1
Development of a panel for detection of pathogens in xenotransplantation donor pigs	1
Opinions of nursing and theology faculty students on Xenotransplantation	1
The Young Investigator Committee of the International Xenotransplantation Association—Perspective of advancements in the field in 2023	1
Close contacts of xenograft recipients: Ethical considerations due to risk of xenozoonosis	1
How Much Will a Pig Organ Transplant Cost? A Preliminary Estimate of the Cost of Xenotransplantation Versus Allotransplantation in the USA	1
The attitudes of religious group leaders towards xenotransplantation: A focus group study	1
Pilot Study: Functional Survival of Human Stem Cell‐Derived Islets Microencapsulated With Alginate Incorporating CXCL12 in Non‐Human Primates Without Systemic Immunosuppression	1
COVER IMAGE	1
Attitudes Toward Renal Xenotransplantation in a Muslim Country: Analysis of Specific Subgroups	1
Assessing Knowledge, Attitudes, and Practices of Healthcare Workers in Saudi Arabia Towards Xenotransplantation: Insights From a Cross‐Sectional Survey	1
RETRACTED: Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication With Preserved Bioactivity: A Comparative Evaluation	1
Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques	1
Systemic inflammation in xenograft recipients (SIXR) or undetected PCMV/PRV transmission?	1
Barriers toward xenotransplantation in Arab World	1
Assessment of glomerular filtration and tubular secretion in baboons with life‐supporting pig kidney grafts	1
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Iscalimab Combined With Transient Tesidolumab Prolongs Survival in Pig‐to‐Rhesus Monkey Renal Xenografts	1
The first clinical pig heart transplant: Was IVIg or pig cytomegalovirus detrimental to the outcome?	1
Transplantation of porcine adrenal spheroids for the treatment of adrenal insufficiency	1
Issue Information	1

Intensive Surveillance of Porcine‐Rhesus Kidney Xenotransplant Using Different Ultrasound Techniques	1
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Short‐term function and immune‐protection of microencapsulated adult porcine islets with alginate incorporating CXCL12 in healthy and diabetic non‐human primates without systemic immune suppression: A	1
Current state of clinical trials on xenograft	1
Characteristics Associated With Acceptance of Porcine Xenotransplantation	1
Investigational New Drug Enabling Nonclinical Study of Xenogeneic Life‐Supporting Porcine Kidneys With 10 Gene Edits (10 GE) in a Nonhuman Primate Test System	1
Issue Information	1
A Report of Four Depletional Induction Strategies in Non‐Human Primate Islet Xenotransplantation	1