Xenotransplantation

Article	Citations
	38
Hendrik Jan (Henk) Schuurman, MSc, PhD (1950–2024): In Memoriam	33
Systemic inflammation in the xenotransplant recipient (SIXR) can occur in the absence of pCMV infection	22
Bioinformatic analysis as a first step to predict the compatibility of hematopoiesis and immune system genes between humans and pigs	22
Xenotransplantation Literature Update July–December 2024	20
A Review of Studies of Perfusion Storage of Pig Kidneys and Their Relevance to Clinical Xenotransplantation	20
Anti‐pig antibodies in swine veterinarian serum: Implications for clinical xenotransplantation	20
Impact of COVID‐19 Vaccination and Infection on Anti‐Triple‐Knockout (TKO) Pig Antibody Production: A Study in Patients With End‐Stage Liver Disease and Liver Transplant Recipients	19
First transplantation of a pig heart from a multiple gene‐modified donor, porcine cytomegalovirus/roseolovirus, and antiviral drugs	17
Transthoracic echocardiography is a simple tool for size matching in cardiac xenotransplantation	15
ECG Features in Orthotopic Cardiac Xenotransplantation: Comparisons With Published Literature	14
Anatomical and Physiological Considerations for Pig Cardiac Xenotransplantation	14
Complement Inhibition in Xenotransplantation–Where Should the Complement Cascade be Inhibited?	14
Issue Information	14
Modified CD40L‐Activated B‐Cell Proliferation Model for Validating the Suppressive Activity of CD40‐CD154 Pathway Inhibitors	13
RETRACTION: An IgM Cleaving Enzyme for Clearance of Anti‐Pig Xenoreactive Antibodies in a Nonhuman Primate Model	13
He reshaped the forefront of xenotransplantation: Agustin Pasqual Dalmasso (1933–2021)	13
Heterogenous expression of endocrine and progenitor cells within the neonatal porcine pancreatic lobes–Implications for neonatal porcine islet xenotransplantation	13
COVER IMAGE	12
An ethical algorithm for xenotransplantation? Further transparency and clarity needed	12
Assessment of Porcine Endogenous Retrovirus Infectivity to Human Cells Using Flowcytometric Isolation After Co‐Culture	12
Xenotransplantation: A historical–ethical account of viewpoints	12
Xenotransplantation Literature Update December 2023–June 2024	12
Xenoreactive antibodies in α‐granules of human platelets bind pig liver endothelial cells	11
Religion and Attitudes Toward Xenotransplantation: Results of a Nationwide Survey in the United States	11

The case for the therapeutic use of mechanistic/mammalian target of rapamycin (mTOR) inhibitors in xenotransplantation	11
Xenotransplantation in the Age of Genome Editing: Results From the Expert Report for the Federal Ethics Committee on Nonhuman Biotechnology With a Special Focus on Animal Ethics	10
Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain	10
Xenotransplantation of pig islet cells: Potential adverse impact of virus infections on their functionality and insulin production	9
Evaluation of Complement‐Dependent Cytotoxicity Assays for Gene‐Edited Pig‐to‐Human Xenotransplantation	9
Defect in Sensing Human Thrombin by Porcine Endothelial Protease‐Activated Receptor‐1: Molecular Incompatibility Between Porcine PAR‐1 and Human Thrombin	9
Issue Information	9
Ethical Analysis of Voluntariness in Pig Kidney Xenotransplant First‐in‐Human Clinical Trials	9
Announcement	8
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Observations on hydronephrosis after pig kidney transplantation in baboons	8
Global Research Trends and Current Status of Xenotransplantation: A Bibliometric Analysis	8
Genetic diversity, growth and heart function of Auckland Island pigs, a potential source for organ xenotransplantation	8
Clinical Pig Kidney Xenotransplantation Rewrites the Rules of Renal Graft Rejection	8
Donor‐Derived Cell‐Free DNA (dd‐cfDNA) as an Early Noninvasive Biomarker of Graft Injury in Pig‐to‐Monkey Islet Xenotransplantation	7
Functional Xenogeneic Liver Support in a Living Human: Promise, Lessons, and Next Steps	7
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Antibodies against hyaluronan oligosaccharides in xenotransplantation	7
Rural Transplant Disparities and Xenotransplantation: Scaling Is Not Enough	7
Vatican Reaffirms Moral Permissibility of Xenotransplantation	7
International Xenotransplantation Association (IXA) Position Paper on the History, Current Status, and Regulation of Xenotransplantation	7
A compositional analysis of native and decellularized porcine nasal septum cartilage	7
Exploring attitudes toward xenotransplantation: A scoping review of healthcare workers, healthcare students, and kidney patients	7
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Xenotransplantation, Ethics, and Pediatric Decedent Studies	7
Pilot Survey of Attitudes Toward Xenotransplantation Among Nursing Students in London, UK	6
Historic progress in xenotransplantation with successful transplantation of genetically‐edited pig kidneys into living recipients	6
The impact of IdeS (imlifidase) on allo‐specific, xeno‐reactive, and protective antibodies in a sensitized rhesus macaque model	6
Porcine Cytomegalovirus/Porcine Roseolovirus (PCMV/PRV) and Antiviral Drugs	6
Asking the Right Questions: Larry Faucette's Journey Through Xenotransplant	6
Humoral Barrier to Preclinical and Clinical Xenotransplantation	6
Comparative Inhibitory Effects of Tacrolimus, Cyclosporine, and Rapamycin on Human Anti‐Pig Xenogeneic Mixed Lymphocyte Reactions	6
Issue Information	6
Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans	6
Two‐day Static Cold Preservation of α1,3‐Galactosyltransferase Knockout Kidney Grafts Before Simulated Xenotransplantation	6
The Emergence of the Asian Xenotransplantation Association: Regional Collaboration in a Rapidly Evolving Field	5
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Alteration of γδ T cell subsets in non‐human primates transplanted with GGTA1 gene‐deficient porcine blood vessels	5
Human CD64 Alleviates Antibody‐Mediated Rejection in Xenotransplantation	5
Harmonizing International Regulatory Standards for Porcine Endogenous Retrovirus (PERV) Screening in Genetically Modified Porcine Donors for First‐in‐Human Pancreatic Islet Xenotransplantation	5
In Memoriam – Guy Alexandre (1934–2024)	5
Removal of Porcine Endogenous Retroviruses in Decellularized Liver Bioscaffolds	5
The International Human Xenotransplantation Inventory: Current Data and Future Directions	5
Methodological Approaches to Improve the Robustness of Bibliometric Studies in Xenotransplantation	5
Large‐Scale Formation and Long‐Term Culture of Hepatocyte Organoids From Streamlined In Vivo Genome‐Edited GGTA1−/− Pigs for Bioartificial Liver Applications	5
Antibody‐mediated rejection in xenotransplantation: Can it be prevented or reversed?	5
RETRACTION: Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication with Preserved Bioactivity: A Comparative Evaluation	5
Renin‐Angiotensin‐Aldosterone System (RAAS) in Pig‐to‐Baboon Kidney Xenotransplantation—Relevance to Clinical Pig Kidney Xenotransplantation	4
Realistic Prospects of Xenotransplantation in Japan: Specific Regulations for Clinical Application	4
Governmental Questionnaire Survey on Adolescent and Young Adults’ Views on the Clinical Application of Xenotransplantation	4

The birth of Dolly and xenotransplantation 25 years on	4
Issue Information	4
Xenotransplantation and Disability Contraindications to Pediatric Heart Transplantation: Are We at the Horizon of Organ Transplantation for any Person That May Benefit?	4
Use of Brain Death Recipients in Xenotransplantation: A Double‐Edged Sword	4
Xenotransplantation Literature Update: July–December 2025	4
Sex Differences in Maturation and Function of Neonatal Porcine Islets Upon Transplantation in Mice	4
In vivo induction of regulatory T cells by anti‐CD45RB antibody causes transferable tolerance to discordant human xenogenic islets	4
How to Detect Porcine Endogenous Retrovirus (PERV) Infections in Patients After Transplantation of Pig Organs	4
In Vitro Evaluation of Basiliximab as an Induction Therapy for Xenotransplantation	4
Treatment of Presumptive Rejection After Orthotopic Pig‐to‐Baboon Cardiac Xenotransplantation	4
Xenotransplantation clinical trials: Should patients with diminished capacity be permitted to enroll?	4
SARS‐CoV‐2 does not infect pigs, but this has to be verified regularly	4
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RETRACTION: Evaluation of Complement‐Dependent Cytotoxicity Assays for Gene‐Edited Pig‐to‐Human Xenotransplantation	4
Long‐term control of diabetes by tofacitinib‐based immunosuppressive regimen after allo islet transplantation in diabetic rhesus monkeys that rejected previously transplanted porcine islets	4
Views of Living Donor Liver Transplant Recipients About Xenotransplantation in Türkiye: A Qualitative Study	3
Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication With Preserved Bioactivity: A Comparative Evaluation	3
Will Pig Organ Xenotransplantation in Patients Complicate the Use of Commonly Administered Drugs?	3
Advances in Subclinical and Clinical Trials and Immunosuppressive Therapies in Xenotransplantation	3
Issue Information	3
Knock‐out of N‐glycolylneuraminic acid attenuates antibody‐mediated rejection in xenogenically perfused porcine lungs	3
CMAH‐Targeted Knock‐In of Inducible Heme Oxygenase‐1 and Constitutive CD47 in GGTA1‐Knockout Pigs for Xenotransplantation	3
In Memoriam: Sir Roy Calne, FRCS, FRS, 1930–2024	3
Which Platform of SARS‐CoV‐2 Vaccines Should be Used for Xenotransplant Recipients?	3
Author List	3
Xenotransplantation at 30 years – A personal reminiscence and some thoughts for the future	3
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Cellular Landscapes of Different Gene‐Edited Pig Hearts Associated With Cardiac Xenotransplantation	3
International Xenotransplantation Association (IXA) Position Paper on Kidney Xenotransplantation	3
Bridging Therapies—Ex Vivo Liver Xenoperfusion and the Role of Machine Perfusion: An Update	3
Patient informed consent for a clinical trial of gene‐edited pig kidney transplantation: A representative consent form	3
“Will I Still be Myself?” Opposition to Xenotransplantation Among Chinese Kidney Transplant Candidates: A Qualitative Study	3
Public Attitudes Toward Xenotransplantation in South Korea: A 2023 Survey Study	3
Noninvasive Monitoring of Complement Using the Bioluminescent Modified Ham Assay in the Second Porcine‐to‐Human Live Heart Transplant	3
Periodic Trajectories of the Plasma Metabolome in a Pig‐to‐Non‐Human Primate Cardiac Xenograft Model	3
Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs	3
Integrated Multi‐Omics Analysis of Coagulation Dysregulation and Immune Pathway Alterations in 10‐Gene Pig‐to‐Monkey Liver Xenotransplantation: A Case Report	3
Novel factors potentially initiating acute antibody‐mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen	2
Non‐Classical Swine Leukocyte Antigens SLA‐6, ‐7, and ‐8, Are Xenoantigens for Some Waitlisted Patients	2
Evaluation of knowledge, attitude, and awareness of liver transplant patients toward xenotransplantation	2
Issue Information	2
Human or Not? An Experimental Investigation of Xenotransplantation Acceptability Across Donation Contexts	2
Abstracts	2
COVER IMAGE	2
Xenotransplantation Literature Update: January–June 2025	2
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A murine groin site cardiac transplantation model—applicable tool for studying roles of peripheral lymph nodes in transplantation	2
Molecular incompatibility between pig CD200 and human CD200 receptor in in vitro xenogeneic immune responses	2
Development and characterization of islet‐derived mesenchymal stem cells from clinical grade neonatal porcine cryopreserved islets	2
Anti–Non‐Gal Antibodies Against Porcine Protein Antigens as Barrier to Long‐Term Grafting of Xenografts in Humans	2
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?	2
Liver Xenotransplantation: Ethical and Societal Implications	2
Quantitative Proteomic Analysis of Cardiac Xenograft Failure in a Pig‐to‐Non‐Human Primate Model Identifies NF‐κB as a Critical Immunomodulatory Target	2
An IgM Cleaving Enzyme for Clearance of Anti‐Pig Xenoreactive Antibodies in a Nonhuman Primate Model	2
Xenotransplantation literature update March 2023–November 2023	2
Issue Information	2
The first clinical pig heart transplant: Was IVIg or pig cytomegalovirus detrimental to the outcome?	1
Transplantation of porcine adrenal spheroids for the treatment of adrenal insufficiency	1
Issue Information	1
Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs	1
Barriers toward xenotransplantation in Arab World	1
Large‐gap peripheral nerve repair using xenogeneic transplants in rhesus macaques	1
Systemic inflammation in xenograft recipients (SIXR) or undetected PCMV/PRV transmission?	1
Current state of clinical trials on xenograft	1
Assessing Knowledge, Attitudes, and Practices of Healthcare Workers in Saudi Arabia Towards Xenotransplantation: Insights From a Cross‐Sectional Survey	1
The attitudes of religious group leaders towards xenotransplantation: A focus group study	1
Lessons learned from the first cardiac xenotransplant in a consciously consenting human: Psychiatric considerations and the impact of media exposure	1
Attitudes Toward Renal Xenotransplantation in a Muslim Country: Analysis of Specific Subgroups	1
Mathieu Jaboulay's (1860–1913) contribution to xenotransplantation	1
Investigational New Drug Enabling Nonclinical Study of Xenogeneic Life‐Supporting Porcine Kidneys With 10 Gene Edits (10 GE) in a Nonhuman Primate Test System	1
RETRACTED: Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication With Preserved Bioactivity: A Comparative Evaluation	1
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The Young Investigator Committee of the International Xenotransplantation Association—Perspective of advancements in the field in 2023	1
Development of a panel for detection of pathogens in xenotransplantation donor pigs	1
Early Experimental Report of the First 8‐Gene‐Edited Pig‐to‐Rhesus Macaque Cardiac Xenotransplantation in China	1
Characteristics Associated With Acceptance of Porcine Xenotransplantation	1
Assessment of glomerular filtration and tubular secretion in baboons with life‐supporting pig kidney grafts	1
Mapping the Evolution of Solid Organ Xenotransplantation Research:A Systematic Review	1
Pilot Study: Functional Survival of Human Stem Cell‐Derived Islets Microencapsulated With Alginate Incorporating CXCL12 in Non‐Human Primates Without Systemic Immunosuppression	1
How Much Will a Pig Organ Transplant Cost? A Preliminary Estimate of the Cost of Xenotransplantation Versus Allotransplantation in the USA	1

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Late graft failure of pig‐to‐rhesus renal xenografts has features of glomerulopathy and recipients have anti‐swine leukocyte antigen class I and class II antibodies	1
Close contacts of xenograft recipients: Ethical considerations due to risk of xenozoonosis	1
Opinions of nursing and theology faculty students on Xenotransplantation	1
A Report of Four Depletional Induction Strategies in Non‐Human Primate Islet Xenotransplantation	1
Iscalimab Combined With Transient Tesidolumab Prolongs Survival in Pig‐to‐Rhesus Monkey Renal Xenografts	1
Short‐term function and immune‐protection of microencapsulated adult porcine islets with alginate incorporating CXCL12 in healthy and diabetic non‐human primates without systemic immune suppression: A	1
Issue Information	1
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Xenotransplantation in China: Past, Present, and Future	1