OOIR: Observatory of International Research

Papers

(The median citation count of Periodontology 2000 is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
The role of the microbiota in periodontal disease	311
Clinical and public health implications of periodontal and systemic diseases: An overview	235
The role of inflammation and genetics in periodontal disease	224
Periodontitis is an inflammatory disease of oxidative stress: We should treat it that way	215
Mechanisms underlying the association between periodontitis and atherosclerotic disease	191
The oral microbiome: Role of key organisms and complex networks in oral health and disease	178
Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy	164
The association of periodontal diseases with metabolic syndrome and obesity	153
The dental plaque biofilm matrix	145
Diabetes as a potential risk for periodontitis: association studies	143
Microbial signatures of health, gingivitis, and periodontitis	122
Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host	121
Effects of periodontal disease on glycemic control, complications, and incidence of diabetes mellitus	113
Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications	107
Oral health’s inextricable connection to systemic health: Special populations bring to bear multimodal relationships and factors connecting periodontal disease to systemic diseases and conditions	104
Periodontal disease and cancer: Epidemiologic studies and possible mechanisms	102
Oral‐lung microbiome interactions in lung diseases	95
Resilience of the oral microbiome	86
Peri‐implantitis is not periodontitis: Scientific discoveries shed light on microbiome‐biomaterial interactions that may determine disease phenotype	83
Osteoporosis and periodontal diseases – An update on their association and mechanistic links	78
Periodontal diseases and adverse pregnancy outcomes: Mechanisms	75
Periodontal diseases and association with atherosclerotic disease	75
Periodontal therapy and cardiovascular risk	75
Periodontal disease and adverse pregnancy outcomes	74
Periodontal disease as a possible cause for Alzheimer's disease	73

Association between metabolic syndrome and periodontitis: The role of lipids, inflammatory cytokines, altered host response, and the microbiome	69
Breaking the wave of peri‐implantitis	69
A bibliometric analysis of periodontology	68
Oral health‐related quality of life of patients rehabilitated with fixed and removable implant‐supported dental prostheses	67
Diabetes as a risk factor for periodontal disease—plausible mechanisms	66
Maintaining homeostatic control of periodontal bone tissue	63
Microbial transitions from health to disease	63
Prosthetic failures in dental implant therapy	62
Periodontitis and rheumatoid arthritis: What have we learned about their connection and their treatment?	59
Periodontitis and rheumatoid arthritis: An update 2012‐2017	56
Contemporary practices for mechanical oral hygiene to prevent periodontal disease	56
A public health approach for prevention of periodontal disease	55
Impact of systemic factors in shaping the periodontal microbiome	53
Acquisition and establishment of the oral microbiota	50
Oral biofilms revisited: A novel host tissue of bacteriological origin	50
Oral and periodontal implications of tobacco and nicotine products	48
Optimizing the quality of clinical studies on oral microbiome: A practical guide for planning, performing, and reporting	48
The prevention of periodontal disease—An overview	47
Probiotics for periodontal health—Current molecular findings	47
Frailty, aging, and periodontal disease: Basic biologic considerations	45
Surgical therapy of peri‐implantitis	45
Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia	45
Patient‐based outcomes and quality of life	44
Periodontal disease–related nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: An emerging concept of oral‐liver axis	42
Reducing errors in guided implant surgery to optimize treatment outcomes	41
Risk factors for periodontitis & peri‐implantitis	40
Complications in sinus lifting procedures: Classification and management	38
Role of Porphyromonas gingivalis in oral and orodigestive squamous cell carcinoma	38
Periodontitis, chronic liver diseases, and the emerging oral‐gut‐liver axis	38
Etiology, occurrence, and consequences of implant loss	37
Prevention and management of periodontal diseases and dental caries in the older adults	37
Complications in bone‐grafting procedures: Classification and management	36
Primer on etiology and treatment of progressive/severe periodontitis: A systemic health perspective	35
It is all about peri‐implant tissue health	35
Viruses, periodontitis, and comorbidities	34
Environmental factors and periodontal microbiome	33
Management and prevention of soft tissue complications in implant dentistry	33
Periodontal health and disease: The contribution of genetics	31
Can computer‐assisted implant surgery improve clinical outcomes and reduce the frequency and intensity of complications in implant dentistry? A critical review	30
Periodontal microorganisms and Alzheimer disease – A causative relationship?	30
Sustained‐release delivery of antimicrobial drugs for the treatment of periodontal diseases: Fantasy or already reality?	30
Fusobacterium nucleatum and cancer	30
Did Omics change periodontal therapy?	30
The psychobiological links between chronic stress‐related diseases, periodontal/peri‐implant diseases, and wound healing	29
The evolutionary history of the human oral microbiota and its implications for modern health	29
Periodontitis and coronavirus disease 2019	28
Inflammation as a link between periodontal disease and obesity	28
Maintaining a protective state for human periodontal tissue	28
The role of foreign body response in peri‐implantitis: What is the evidence?	27
Dendritic cells a critical link to alveolar bone loss and systemic disease risk in periodontitis: Immunotherapeutic implications	27

Association between periodontitis and chronic kidney disease	26
Periodontitis and implant complications in diabetes	25
Paradigm shift in the pathogenesis and treatment of oral cancer and other cancers focused on the oralome and antimicrobial‐based therapeutics	25
Metatranscriptomic analyses of the oral microbiome	25
Periodontology and pregnancy: An overview of biomedical and epidemiological evidence	24
The human oral phageome	24
Metaproteome and metabolome of oral microbial communities	24
Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives	23
Mental health and periodontal and peri‐implant diseases	23
The role of cigarette smoking in periodontal disease and treatment outcomes of dental implant therapy	23
Oral microbiome shifts during pregnancy and adverse pregnancy outcomes: Hormonal and Immunologic changes at play	21
The human oral virome: Shedding light on the dark matter	21
Esthetic complications in implant dentistry	21
Alzheimer disease and the periodontal patient: New insights, connections, and therapies	20
Oral bacteria, oral health, and adverse pregnancy outcomes	20
Spatial scale in analysis of the dental plaque microbiome	19
Pros and cons of causative association between periodontitis and rheumatoid arthritis	19
Minimal invasiveness in soft tissue augmentation at dental implants: A systematic review and meta‐analysis of patient‐reported outcome measures	18
Waistline to the gumline: Relationship between obesity and periodontal disease‐biological and management considerations	18
Fungal diseases: Oral dysbiosis in susceptible hosts	18
Novel natural product‐based oral topical rinses and toothpastes to prevent periodontal diseases	17
Treatment planning considerations in the older adult with periodontal disease	17
Biological strategies for the prevention of periodontal disease: Probiotics and vaccines	17
Microbiomics: Were we all wrong before?	17
Maintaining homeostatic control of periodontal epithelial tissue	17
Periodontal connection with intestinal inflammation: Microbiological and immunological mechanisms	17
Overcoming behavioral obstacles to prevent periodontal disease: Behavioral change techniques and self‐performed periodontal infection control	16
Impact of calorie restriction and intermittent fasting on periodontal health	16
Subgingival fungi, Archaea, and viruses under the omics loupe	16
Minimal invasiveness at dental implant placement: A systematic review with meta‐analyses on flapless fully guided surgery	16
Wound healing dynamics, morbidity, and complications of palatal soft‐tissue harvesting	15
What periodontal recall interval is supported by evidence?	15
Interventions to prevent periodontal disease in tobacco‐, alcohol‐, and drug‐dependent individuals	15
Probing periodontal microbial dark matter using metataxonomics and metagenomics	15
Human and herpesvirus microRNAs in periodontal disease	15
Clinical and patient‐reported outcomes of tissue engineering strategies for periodontal and peri‐implant reconstruction	14
Peri‐implantitis as the consequence of errors in implant therapy	14
Biological mechanisms underlying complications related to implant site preparation	13
Management and sequelae of dental implant removal	13
The role of systemic diseases and local conditions as risk factors	13
Influence of epigenetics on periodontitis and peri‐implantitis pathogenesis	12
Maladaptive trained immunity and clonal hematopoiesis as potential mechanistic links between periodontitis and inflammatory comorbidities	12
Oral health status and the etiology and prevention of nonventilator hospital‐associated pneumonia	11
Impact of health and lifestyle food supplements on periodontal tissues and health	10
Myeloid‐derived suppressor cells in obesity‐associated periodontal disease: A conceptual model	10
Life‐threatening pathogens in severe/progressive periodontitis: Focal infection risk, future periodontal practice, role of the Periodontology 2000	10
Alveolar ridge preservation: Complications and cost‐effectiveness	10
Omics and interspecies interaction	9
Complications and treatment errors in periodontal and implant therapy	9
Periodontitis and peri‐implantitis in elderly people experiencing institutional and hospital confinement	9