OOIR: Observatory of International Research

Papers

(The TQCC of Chirality is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Featured Cover	95
Resolution and Absolute Configuration of Fargesin Enantiomers	94
Synthesis and separation of diastereomeric N‐(1‐phenylethyl)amides of inherently chiral hydroxydibenzoyloxy‐calix[4]arene acetic acids	75
Development of a novel HPLC‐ESI‐MS/MS method to analyze the stereoselective pharmacokinetics and tissue distribution of isoconazole enantiomers in rats	61
Enantiomeric composition of natural pericosine A derived from Periconia byssoides and α‐glycosidase inhibitory activity of (−)‐enantiomer	52
A concise review on recent advances in catalytic asymmetric hydrogenation	52
Enantiomeric separation of tryptophan via novel chiral polyamide composite membrane	47
New enantioselective liquid chromatography method development and validation of dipeptidyl peptidase IV inhibitors using a macrocyclic glycopeptide (vancomycin) chiral stationary phase under polar ion	40
Graph‐theoretical chirality measure and chirality–property relations for chemical structures with multiscale mirror asymmetries	38
Chiral diketopyrrolo[3,4‐c]pyrrole‐based oligothiophenes: Synthesis and characterization of aggregated states in solution and thin films	36
	32
	31
Electrochemiluminescent Chiral Sensor Based on Covalent Organic Frameworks for Discrimination of Phenylalanine Enantiomers	28
	28
Continuous chiral distances for two‐dimensional lattices	28
	24
Self‐assembly of chiral diketopyrrolopyrrole chromophores giving supramolecular chains in monolayers and twisted microtapes	22
Molecular modifications, biological activities, and applications of chitosan and derivatives: A recent update	22
Homochiral zeolites as chiral modifier for voltammetry sensors with high enantioselectivity	21
Development of Acid‐Functionalized Molecularly Imprinted Phenolic Resin for Chiral Recognition of S‐Venlafaxine	20
Study on the anti‐cancer activity of α‐phenethylamine ferrocenecarboxylic acid co‐crystals	20
Stereoisomeric Separation of Flavonoids by Two‐Dimensional Supercritical Fluid Chromatography: Identification of Adequate Chiral Columns and Application to Honey Analysis	20
Comparative enantioseparation of planar chiral ferrocenes on polysaccharide‐based chiral stationary phases	20
Cover Image, Volume 35, Issue 7	19
Enantioseparation and molecular modeling study of chiral amines as three naphthaldimine derivatives using amylose or cellulose trisphenylcarbamate chiral stationary phases	17

Stereoselective synthesis of 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids	17
	17
Exploring Naproxen Cocrystals Through Solid‐State Vibrational Circular Dichroism	16
Advancement in chiral heterocycles for the antidiabetic activity	16
Chiral phonons: circularly polarized Raman spectroscopy and ab initio calculations in a chiral crystal tellurium	15
Expanding the Role of Chiral Drugs and Chiral Nanomaterials as a Potential Therapeutic Tool	15
Enantioselective high‐performance liquid chromatography combined with spectroscopic methods and theoretical calculations: A valid strategy to determine the absolute configuration of eugenol derivative	15
	14
	14
	14
Issue Information	13
Research on promoting the asymmetric reaction of phenylacetylene with aldehydes by chloramphenicol base ligands	13
A covalent organic framework for chiral capillary electrochromatography using a cyclodextrin mobile phase additive	12
Switching the on‐surface orientation of oxygen‐functionalized helicene	12
Computing the electronic circular dichroism spectrum of DNA quadruple helices of different topology: A critical test for a generalized excitonic model based on a fragment diabatization	11
Evaluation of chiral N,N‐dimethyl‐sphingosine for the interaction between nerve growth factor and tropomyosin receptor kinase A	11
Resolution of trans‐1,2‐cyclohexanedicarboxylic acid containing two carboxylic groups by forming diastereomeric salts based on feeding molar ratio control	10
On the choice of coordinate origin in length gauge optical rotation calculations	10
Enantiomeric Analysis of Chiral Drugs Using Mass Spectrometric Methods: A Comprehensive Review	10
Preparation of a bis‐triazolyl bridged β‐cyclodextrin stationary phase and its application for enantioseparation of chiral compounds by HPLC	10
Issue Information	10
Chiral probe for mass spectrometric identification and quantitation of levodropropizine and its enantiomer, dextrodropropizine	10
Correction to “Effect of chirality in the supramolecular polymerization of N‐annulated perylenediimides: Cancelling pathway complexity”	10
Principles for Stereoselective Separation of Chiral Drug Compounds Enantiomers and Diastereomers in Pharmaceuticals and Biopharmaceuticals Using Liquid Chromatography	9
Issue Information	9
Chiral Ionic Liquids for Enantioselective Liquid–Liquid Extraction of DL‐3‐Phenyllactic Acid: Synthesis, Characterization, and Mechanistic Insights	9
Chiral LC–MS/MS method for the discrimination of triiodothyronine enantiomers on a crown ether‐based chiral stationary phase	9
Separation of enantiomers of chiral fullerene derivatives through enantioselective encapsulation within an adaptable helical cavity of syndiotactic poly(methyl methacrylate) with helicity memory	9
Different degradation patterns and mechanisms of chiral contaminant enantiomers: beta‐cypermethrin as a case study	9
Remarkable enantioselectivity enhancement of the extractors with nonaxial chirality in liquid–liquid extraction of underivatized amino acids by introducing t‐butyl group	9
Catalytic Performance of Chiral Tetraaza‐Bridged Calix[4]arene[2]triazine Derivatives for Enantioselective Michael Reactions	9
Issue Information	9
Enantioseparation of linezolid and tedizolid using validated high‐performance liquid chromatographic method	9
A recent update on new synthetic chiral compounds with antileishmanial activity	9
	8
Cover Image, Volume 35, Issue 2	8
Issue Information	8
Spectroscopic Study of R‐ and S‐Ketoprofen Inclusion Complexes With 2‐Hydroxypropyl‐β‐cyclodextrin	8
Issue Information	8
Optimizing Enantiomeric Resolution of Chiral Triazoles in Supercritical Fluid Chromatography	8
Featured Cover	8
Time‐Dependent Resolution of an Atropisomeric 1‐Arylpyrrole by a Novel 1‐Arylethylamine Saltforming Agent	8
Cover Image, Volume 36, Issue 6	8
Size dependence of optical activities in helical polymers	8
Circularly polarized and total luminescence as probes of nucleation and growth in chiral nanocrystals	7
	7
Determination of Enantiomeric Excess via ³¹P‐NMR	7
Development and validation of a novel chiral chromatographic method for separation of lenalidomide enantiomers in human plasma	7
Enantioseparation and Determination for Racemate Carnitine Based on a Chiral Hybrid Material Synthesized by Metal Organic Framework and Covalent Organic Framework in Capillary Electrochromatography	7
Concentration and pH effect on the electronic circular dichroism and anisotropy spectra of aqueous solutions of glyceric acid calcium salt	7

	7
Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier	7
	7
Editors' note	7
Chiral separation of dipeptides on Cinchona‐based zwitterionic chiral stationary phases under buffer‐free reversed‐phase conditions	6
Chiral recognition mechanism studies of Tyr‐Arg‐Phe‐Lys‐NH₂ tetrapeptide on crown ether‐based chiral stationary phase	6
	6
Computational Molecular Docking Analysis of Linalool Enantiomers Interaction With Mitogen‐Activated Protein Kinase 1 (MAPK1): Insights Into Potential Binding Mechanisms and Affinity	6
Issue Information	6
Cross‐Catalysis and Weak Interactions: Keys to the Chiral Polarization of the Biosphere	6
An Enzymatic Method to Obtain Enantiopure 3‐Pyridyl and Substituted Phenyl Alanine	6
Issue Information	6
Enantioselective voltammetric sensor based on mesoporous graphitized carbon black Carbopack X and fulvene derivative	6
	5
Molecular Docking Observations on Enantiomeric Retention Trends and Selection of Chiral Stationary Phase	5
Resolution of N‐acetyl‐DL‐methionine methyl ester by the lipase from Brucella thiophenivorans	5
Comparative rotatory power of bent and twisted polyynes	5
Enantioselective Degradation and Processing Factors of Seven Chiral Pesticides During the Processing of Wine and Rice Wine	5
Lipase mediated new chemo‐enzymatic synthesis of (RS)‐, (R)‐, and (S)‐bunolol	5
Chiral recognition of tryptophan enantiomer based on the electrode modified by polyaniline adsorption bovine serum albumin complex	5
Chiral Post‐Modification of UiO‐66‐NH₂ on Gas Chromatography Chiral Separation	5
Voltammetric Sensor for Naproxen Enantiomers Based on a Paste Electrode Modified With a Chiral Nickel(II) Complex	5
Controlling Sign and Magnitude of Circularly Polarized Luminescence of Axially Chiral Schiff‐Base Boron Difluoride Complexes Bearing Polyethylene Glycol Chains	5
Chiral Chromatography and Artificial Intelligence Integration in Enantiomers Separation	5
Enantioselective Analysis and Separation of Two β‐Blockers via Derivatization Approach	5
Determination of N‐centered stereochemistry in N22‐methylated chlorophyll‐a derivatives and their epimer‐dependent optical spectra	5
Valbenazine isomers and enantiomer determination by chiral normal phase liquid chromatography	5
Achiral 2‐pyridone and 4‐aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals	5
Induced Chirality in Sulfasalazine by Complexation With Albumins: Theoretical and Experimental Study	5
Issue Information	5
Determination of chiral bioactive molecules in Justicia adhatoda leaves by GC–MS	5
Issue Information	4
Chiral Chromatographic Separation of Fifteen New Hexahydroquinoline Derivatives	4
Featured Cover	4
Issue Information	4
2‐O‐Acetyl‐3,4,5,6‐tetra‐O‐benzyl‐d‐myo‐inosityl diphenylphosphate: A new useful intermediate to inositol phosphate and phospholipids	4
Air‐tolerant upconverted circularly polarized luminescence enabled by confined space of chiral micelle	4
Comparison of percutaneous permeation profiles of flurbiprofen enantiomers	4
Cover Image, Volume 34, Issue 11	4
Secondary structural analyses of histone H2A‐H2B proteins extracted from heated cells	4
Impact of chiral ligands on photophysical and electro‐optical properties of β‐diketonate europium complexes in circularly polarized OLEDs	4
	4
	4
Stereoselectivity of paclobutrazol enantiomers to oxidative stress in wheat	4
Gram‐scale synthesis of (S)‐1‐(thiophen‐2‐yl)ethanol in high enantiomeric purity under Enterococcus faecium BY48 biocatalysts	4
Development of robust chiroptical systems through spirobifluorenes	4
Biological applications of chiral inorganic nanomaterials	4
Enantioselective separation and determination of ibuprofen: Stereoselective pharmacokinetics, pharmacodynamics and analytical methods	4
Chiral acidic molecularly imprinted polymer for enantio‐separation of norepinephrine racemate	4
Towards enantioselective ultrahigh performance liquid chromatography–mass spectrometry‐based metabolomics of branched‐chain fatty acids and anteiso‐fatty acids under reversed‐phase conditions u	4
Issue Information	4
Issue Information	4
Straightforward synthesis of chiral sulfonate‐based ionic liquids from amino alcohols for chiral recognition	4
Chiral Differentiation of Chiral Lactides and Chiral Diketones on Native and Phenylcarbamoylated Cyclodextrin Chiral Stationary Phases	4
Individual scale factor approach for the vibrational circular dichroism similarity‐guided spectral and conformational analysis of perezone and dihydroperezone	4
Quantification of Oseltamivir Phosphate Enantiomeric Impurity by Chiral HPLC Method With the Aid of Solvent Extraction and Phosphate Salt‐Out Method	4
Photo racemization of 2,2′‐dihydroxy‐1,1′‐binaphthyl derivatives	4