OOIR: Observatory of International Research

Papers

(The TQCC of Chirality is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Chiral diketopyrrolo[3,4‐c]pyrrole‐based oligothiophenes: Synthesis and characterization of aggregated states in solution and thin films	104
A concise review on recent advances in catalytic asymmetric hydrogenation	94
Enantiomeric separation of tryptophan via novel chiral polyamide composite membrane	90
Featured Cover	72
Resolution and Absolute Configuration of Fargesin Enantiomers	58
Synthesis and separation of diastereomeric N‐(1‐phenylethyl)amides of inherently chiral hydroxydibenzoyloxy‐calix[4]arene acetic acids	50
New enantioselective liquid chromatography method development and validation of dipeptidyl peptidase IV inhibitors using a macrocyclic glycopeptide (vancomycin) chiral stationary phase under polar ion	48
Graph‐theoretical chirality measure and chirality–property relations for chemical structures with multiscale mirror asymmetries	43
Enantiomeric composition of natural pericosine A derived from Periconia byssoides and α‐glycosidase inhibitory activity of (−)‐enantiomer	39
Development of a novel HPLC‐ESI‐MS/MS method to analyze the stereoselective pharmacokinetics and tissue distribution of isoconazole enantiomers in rats	37
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Electrochemiluminescent Chiral Sensor Based on Covalent Organic Frameworks for Discrimination of Phenylalanine Enantiomers	28
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Comparative enantioseparation of planar chiral ferrocenes on polysaccharide‐based chiral stationary phases	25
Homochiral zeolites as chiral modifier for voltammetry sensors with high enantioselectivity	25
Self‐assembly of chiral diketopyrrolopyrrole chromophores giving supramolecular chains in monolayers and twisted microtapes	24
Continuous chiral distances for two‐dimensional lattices	21
Development of Acid‐Functionalized Molecularly Imprinted Phenolic Resin for Chiral Recognition of S‐Venlafaxine	21
Molecular modifications, biological activities, and applications of chitosan and derivatives: A recent update	21
Study on the anti‐cancer activity of α‐phenethylamine ferrocenecarboxylic acid co‐crystals	20
Cover Image, Volume 35, Issue 7	20
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Enantioselective high‐performance liquid chromatography combined with spectroscopic methods and theoretical calculations: A valid strategy to determine the absolute configuration of eugenol derivative	19

Stereoselective synthesis of 3,4‐dihydropyrrolo[1,2‐a]pyrazin‐1(2H)‐one derivatives as PIM kinase inhibitors inspired from marine alkaloids	18
Chiral phonons: circularly polarized Raman spectroscopy and ab initio calculations in a chiral crystal tellurium	17
Exploring Naproxen Cocrystals Through Solid‐State Vibrational Circular Dichroism	17
Advancement in chiral heterocycles for the antidiabetic activity	17
Enantioseparation and molecular modeling study of chiral amines as three naphthaldimine derivatives using amylose or cellulose trisphenylcarbamate chiral stationary phases	15
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Expanding the Role of Chiral Drugs and Chiral Nanomaterials as a Potential Therapeutic Tool	15
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Issue Information	14
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Resolution of trans‐1,2‐cyclohexanedicarboxylic acid containing two carboxylic groups by forming diastereomeric salts based on feeding molar ratio control	14
Research on promoting the asymmetric reaction of phenylacetylene with aldehydes by chloramphenicol base ligands	13
Enantiomeric Analysis of Chiral Drugs Using Mass Spectrometric Methods: A Comprehensive Review	12
On the choice of coordinate origin in length gauge optical rotation calculations	12
Evaluation of chiral N,N‐dimethyl‐sphingosine for the interaction between nerve growth factor and tropomyosin receptor kinase A	12
Switching the on‐surface orientation of oxygen‐functionalized helicene	12
Preparation of a bis‐triazolyl bridged β‐cyclodextrin stationary phase and its application for enantioseparation of chiral compounds by HPLC	11
Correction to “Effect of chirality in the supramolecular polymerization of N‐annulated perylenediimides: Cancelling pathway complexity”	10
Absolute configuration assignment of stigmasterol oxiranes	10
Separation of enantiomers of chiral fullerene derivatives through enantioselective encapsulation within an adaptable helical cavity of syndiotactic poly(methyl methacrylate) with helicity memory	10
Computing the electronic circular dichroism spectrum of DNA quadruple helices of different topology: A critical test for a generalized excitonic model based on a fragment diabatization	10
A covalent organic framework for chiral capillary electrochromatography using a cyclodextrin mobile phase additive	10
Issue Information	10
Chiral probe for mass spectrometric identification and quantitation of levodropropizine and its enantiomer, dextrodropropizine	10
Issue Information	10
Transition metal complexes bearing atropisomeric saturated NHC ligands	9
Chiral Ionic Liquids for Enantioselective Liquid–Liquid Extraction of DL‐3‐Phenyllactic Acid: Synthesis, Characterization, and Mechanistic Insights	9
Different degradation patterns and mechanisms of chiral contaminant enantiomers: beta‐cypermethrin as a case study	9
A recent update on new synthetic chiral compounds with antileishmanial activity	9
Chiral LC–MS/MS method for the discrimination of triiodothyronine enantiomers on a crown ether‐based chiral stationary phase	9
Remarkable enantioselectivity enhancement of the extractors with nonaxial chirality in liquid–liquid extraction of underivatized amino acids by introducing t‐butyl group	9
Enantioseparation of linezolid and tedizolid using validated high‐performance liquid chromatographic method	9
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Catalytic Performance of Chiral Tetraaza‐Bridged Calix[4]arene[2]triazine Derivatives for Enantioselective Michael Reactions	8
Issue Information	8
Cover Image, Volume 36, Issue 6	8
Principles for Stereoselective Separation of Chiral Drug Compounds Enantiomers and Diastereomers in Pharmaceuticals and Biopharmaceuticals Using Liquid Chromatography	8
Issue Information	8
Cover Image, Volume 35, Issue 2	8
Chiral organic stereochemistry: Chiral HPLC, chiral auxiliaries, CD spectroscopy, X‐ray crystallography, and light‐powered chiral molecular motors	8
Circularly polarized luminescence of Eu(III) complexes with chiral 1,1′‐bi‐2‐naphtol‐derived bisphosphate ligands	8
Spectroscopic Study of R‐ and S‐Ketoprofen Inclusion Complexes With 2‐Hydroxypropyl‐β‐cyclodextrin	8
Size dependence of optical activities in helical polymers	8
Featured Cover	8
Concentration and pH effect on the electronic circular dichroism and anisotropy spectra of aqueous solutions of glyceric acid calcium salt	7
Determination of Enantiomeric Excess via ³¹P‐NMR	7
Rational design of highly enantioselective composite voltammetric sensors using a computationally predicted chiral modifier	7
Development and validation of a novel chiral chromatographic method for separation of lenalidomide enantiomers in human plasma	7
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Editors' note	7

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Circularly polarized and total luminescence as probes of nucleation and growth in chiral nanocrystals	7
Optimizing Enantiomeric Resolution of Chiral Triazoles in Supercritical Fluid Chromatography	7
Racemization mechanism of lithium tert‐butylphenylphosphido‐borane: A kinetic insight	7
An Enzymatic Method to Obtain Enantiopure 3‐Pyridyl and Substituted Phenyl Alanine	7
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Issue Information	7
Time‐Dependent Resolution of an Atropisomeric 1‐Arylpyrrole by a Novel 1‐Arylethylamine Saltforming Agent	7
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Enantioselective voltammetric sensor based on mesoporous graphitized carbon black Carbopack X and fulvene derivative	6
Issue Information	6
Chiral recognition mechanism studies of Tyr‐Arg‐Phe‐Lys‐NH₂ tetrapeptide on crown ether‐based chiral stationary phase	6
Cross‐Catalysis and Weak Interactions: Keys to the Chiral Polarization of the Biosphere	6
Issue Information	6
Impact of cyclofructan derivatives as efficient chiral selector in chiral analysis: An overview	6
Computational Molecular Docking Analysis of Linalool Enantiomers Interaction With Mitogen‐Activated Protein Kinase 1 (MAPK1): Insights Into Potential Binding Mechanisms and Affinity	6
Macromolecular helicity induction and static helicity memory of poly(biphenylylacetylene)s bearing aromatic pendant groups and their use as chiral stationary phases for high‐performance liquid chromat	6
Chiral separation of dipeptides on Cinchona‐based zwitterionic chiral stationary phases under buffer‐free reversed‐phase conditions	6
Molecular Docking Observations on Enantiomeric Retention Trends and Selection of Chiral Stationary Phase	5
Determination of N‐centered stereochemistry in N22‐methylated chlorophyll‐a derivatives and their epimer‐dependent optical spectra	5
Chiral Post‐Modification of UiO‐66‐NH₂ on Gas Chromatography Chiral Separation	5
Resolution of N‐acetyl‐DL‐methionine methyl ester by the lipase from Brucella thiophenivorans	5
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Induced Chirality in Sulfasalazine by Complexation With Albumins: Theoretical and Experimental Study	5
Achiral 2‐pyridone and 4‐aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals	5
Voltammetric Sensor for Naproxen Enantiomers Based on a Paste Electrode Modified With a Chiral Nickel(II) Complex	5
Issue Information	5
Chiral recognition of tryptophan enantiomer based on the electrode modified by polyaniline adsorption bovine serum albumin complex	5
Comparative rotatory power of bent and twisted polyynes	5
Enantioselective Analysis and Separation of Two β‐Blockers via Derivatization Approach	5
Controlling Sign and Magnitude of Circularly Polarized Luminescence of Axially Chiral Schiff‐Base Boron Difluoride Complexes Bearing Polyethylene Glycol Chains	5
DABCO‐based chiral ionic liquids as recoverable and reusable organocatalyst for asymmetric Diels–Alder reaction	5
Enantioselective Degradation and Processing Factors of Seven Chiral Pesticides During the Processing of Wine and Rice Wine	5
Valbenazine isomers and enantiomer determination by chiral normal phase liquid chromatography	5
Issue Information	4
Stereoselectivity of paclobutrazol enantiomers to oxidative stress in wheat	4
Determination of chiral bioactive molecules in Justicia adhatoda leaves by GC–MS	4
Issue Information	4
Air‐tolerant upconverted circularly polarized luminescence enabled by confined space of chiral micelle	4
Individual scale factor approach for the vibrational circular dichroism similarity‐guided spectral and conformational analysis of perezone and dihydroperezone	4
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Biological applications of chiral inorganic nanomaterials	4
Quantification of Oseltamivir Phosphate Enantiomeric Impurity by Chiral HPLC Method With the Aid of Solvent Extraction and Phosphate Salt‐Out Method	4
Lipase mediated new chemo‐enzymatic synthesis of (RS)‐, (R)‐, and (S)‐bunolol	4
Development of robust chiroptical systems through spirobifluorenes	4
Straightforward synthesis of chiral sulfonate‐based ionic liquids from amino alcohols for chiral recognition	4
Featured Cover	4
Towards enantioselective ultrahigh performance liquid chromatography–mass spectrometry‐based metabolomics of branched‐chain fatty acids and anteiso‐fatty acids under reversed‐phase conditions u	4
Photo racemization of 2,2′‐dihydroxy‐1,1′‐binaphthyl derivatives	4
Issue Information	4
Chiral Chromatographic Separation of Fifteen New Hexahydroquinoline Derivatives	4
Impact of chiral ligands on photophysical and electro‐optical properties of β‐diketonate europium complexes in circularly polarized OLEDs	4
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Issue Information	4
Gram‐scale synthesis of (S)‐1‐(thiophen‐2‐yl)ethanol in high enantiomeric purity under Enterococcus faecium BY48 biocatalysts	4
Chiral Differentiation of Chiral Lactides and Chiral Diketones on Native and Phenylcarbamoylated Cyclodextrin Chiral Stationary Phases	4
2‐O‐Acetyl‐3,4,5,6‐tetra‐O‐benzyl‐d‐myo‐inosityl diphenylphosphate: A new useful intermediate to inositol phosphate and phospholipids	4
A novel isosteviol‐based bifunctional squaramide organocatalyst for enantioselective Michael addition of acetylacetone to nitroolefins	4
Secondary structural analyses of histone H2A‐H2B proteins extracted from heated cells	4
Metal–organic frameworks in chiral separation of pharmaceuticals	4
Comparison of percutaneous permeation profiles of flurbiprofen enantiomers	4