Cellular Signalling

Papers
(The TQCC of Cellular Signalling is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Methylation and transcriptome analyses construct a prognostic model and reveal the suppressor role of VMO1 in lung adenocarcinoma117
Genome-scale CRISPR-Cas9 screening stratifies pancreatic cancer with distinct outcomes and immunotherapeutic efficacy91
PPP1CA promotes hepatocellular carcinoma progression in a YAP1-dependent way69
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage62
TIGAR attenuates intervertebral disc degeneration via autophagy-mediated Keap1 degradation and Nrf2 nuclear translocation to suppress nucleus pulposus pyroptosis56
Corrigendum to “GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway” [Cellular Signalin48
ArfGAP3 regulates vesicle transport and glucose uptake in myoblasts48
Comprehensive split TEV based protein-protein interaction screening reveals TAOK2 as a key modulator of Hippo signalling to limit growth48
Annexin A2 binds the 3′-UTR of H2AX mRNA and regulates histone-H2AX-derived hypoxia-inducible factor 1-alpha activation46
A novel role of ADAMTS16 in renal fibrosis through activating TGF-β/Smad signaling45
Circ_Mkrn2 facilitates the progression of atrial fibrillation via sponging miR-10b-5p42
Editorial Board42
Uptake of ox-LDL by binding to LRP6 mediates oxidative stress-induced BMSCs senescence promoting obesity-related bone loss41
Paeoniflorin suppresses the phenotypic transformation of vascular smooth muscle cells during atherosclerosis by regulating the MAPK/NF-κB pathways and ABCA1 expression41
Mechanical stress induced EndoMT in endothelial cells through PPARγ downregulation41
Primary cilium restricts TGF-β/SMAD signaling induced RIBEs in the co-culture model.40
DUSP2 affects bladder cancer prognosis by down-regulating MEK/ERK and P38 MAPK signaling pathways through PTPN739
TSG101 overexpression enhances metastasis in oral squamous cell carcinoma through cell cycle regulation39
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor39
Targeting CDK12 rescues C/EBPβ-mediated platinum and PARP inhibitor resistance in ovarian cancer38
DSCR1–1 attenuates osteoarthritis-associated chondrocyte injury by regulating the CREB1/ALDH2/Wnt/β-catenin axis: An in vitro and in vivo study38
Effect of fibroblasts small- conductance Ca2+ -activated potassium channel subtype 2 (SK2) on myocardial fibrosis in pressure overload mouse37
Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency37
Nuak kinase signaling in development and disease of the central nervous system37
KCa3.1 upregulation mediated by Ang II-induced JNK/AP-1 activation contributes to atrial fibrosis37
Caveolin-1 drives vasculogenic mimicry in lung adenocarcinoma through autophagy-mediated glycolytic reprogramming36
IFI6 regulation of physiological functions in granulosa cells36
Phosphorylation of mammalian mitochondrial EF-Tu by Fyn and c-Src kinases36
HOXA1 promotes aerobic glycolysis and cancer progression in cervical cancer35
METTL3 promotes the growth and metastasis of pancreatic cancer by regulating the m6A modification and stability of E2F535
The main molecular mechanisms of ferroptosis and its role in chronic kidney disease35
Lactate induces oxidative phosphorylation in osteoblasts via Gpr81–Stat3 signaling35
Identification of the PP1 interactome in human dental pulp: Insights for regenerative strategies34
GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway34
Exosomal circ_0008803 drives lung cancer cell migration and invasion via NF-κB activation34
The role of microRNA-induced apoptosis in diverse radioresistant cancers34
S100P facilitates LUAD progression via PKA/c-Jun-mediated tumor-associated macrophage recruitment and polarization34
Role of moesin and its phosphorylation in VE-cadherin expression and distribution in endothelial adherens junctions33
Importin α as a central regulator of nucleocytoplasmic transport: Structural basis, isoform diversification, and disease implications33
METTL3 contributes to osimertinib resistance in non-small cell lung cancer cell lines by regulating CDC25A and AURKB mRNA stability33
LncRNA Malat1 regulates iPSC-derived β-cell differentiation by targeting the miR-15b-5p/Ihh axis32
MCC in the spotlight: Its dual role in signal regulation and oncogenesis32
Activating transcription factor 6 protects against endothelial barrier dysfunction32
Mechanisms and therapeutic potential of multiple forms of programmed cell death in renal fibrosis32
Oncolytic HSV-1 suppresses cell invasion through downregulating Sp1 in experimental glioblastoma32
The renin-angiotensin-aldosterone system: An old tree sprouts new shoots31
Exploring m6A methylation in skin Cancer: Insights into molecular mechanisms and treatment30
The miR-7 family: an evolutionary conservation and multifunctional miRNA family30
Corrigendum to “VDAC1-mediated cytosolic leakage of mtDNA triggers pyroptosis of nucleus pulposus cells by activating the TLR9 signaling pathway” [Cellular Signaling 142 (2026) 112387].29
E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma29
DCN promotes dermal papilla cells proliferation by escaping chi-miR-497-5p mediated repression via circPIEZO2 sponging29
Retraction notice to "A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates α2M*-induced signalling" [Cellular Signalling 16 (2004) 929-938]29
PPARG-FABP4 regulates PI3K/Akt pathway to promote lung cancer-associated macrophage endoplasmic reticulum stress-mediated CD36 expression and affects lung squamous cell carcinoma metastasis28
The KSR1/MEK/ERK signaling pathway promotes the progression of intrauterine adhesions28
Hypoxia and ferroptosis28
Oncogenic crosstalk between ErbB2, nucleolin and Ras27
METTL3-mediated m6A RNA modification promotes corneal neovascularization by upregulating the canonical Wnt pathway during HSV-1 infection27
Circadian clock regulation of myofibroblast fate27
Hsp70/CHIP E3 ligase complex triggers K149-linked ubiquitination and degradation of BEST1 mutants p.P233L and p.P346H, impairing chloride channel function and retinal integrity27
Pannexin1: A potential therapeutic target for multi-organ ischemic diseases27
Paricalcitol attenuates oxidative stress and inflammatory response in the liver of NAFLD rats by regulating FOXO3a and NFκB acetylation27
Identification of resident progenitors labeled with Top2a responsible for proximal tubular regeneration in ischemia reperfusion-induced acute kidney injury27
Corrigendum to “Ginsenoside inhibits aerobic glycolysis in hepatocellular carcinoma through the hsa-miR-139-5p/AURKA axis” [Cellular Signalling 136 (2025) 112177]27
The YAP1 and EPHA3 receptor tyrosine kinase axis regulates cellular plasticity and treatment response26
ACSL4 coordinates metabolic and cell cycle reprogramming to promote endometrial cancer progression26
The super-enhancer regulatory gene SH2D1A promotes the progression of T cell acute lymphoblastic leukemia by activating CHI3L226
The emerging significance of the METTL family as m6A-modified RNA methyltransferases in head and neck cancer26
Corrigendum to “Hsp70/CHIP E3 ligase complex triggers K149-linked ubiquitination and degradation of BEST1 mutants p.P233L and p.P346H, impairing chloride channel function and retinal integrity” [Cellu26
RETRACTED: Exploring the role of astrocytic dysfunction and AQP4 in depression26
DTX3L promotes renal cell carcinoma progression via ubiquitination and degradation of LATS226
Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine26
HKDC1 promotes autophagy and proliferation in pancreatic adenocarcinoma through interaction with PARP1 and poly(ADP-ribosyl)ation26
NOX4 alleviates breast cancer cell aggressiveness by co-ordinating mitochondrial turnover through PGC1α/Drp1 axis26
Zika virus NS1 suppresses VE-cadherin via hsa-miR-29b-3p/DNMT3b/MMP-9 pathway in human brain microvascular endothelial cells25
NCAPG promotes epithelial-mesenchymal transition through SIP-dependent ubiquitination regulation of β-catenin in hepatocellular carcinoma25
Sustained systemic inflammation increases autophagy and induces EMT/fibrotic changes in mouse liver cells: Protection by melatonin25
Potential role of Hematopoietic PBX-Interacting Protein (HPIP) in trophoblast fusion and invasion: Implications in pre-eclampsia pathogenesis25
PDCD4 exacerbates myocardial ischemia-reperfusion injury via AKT-mediated apoptosis25
Promoting the proliferation of osteoarthritis chondrocytes by resolvin D1 regulating the NLRP3/caspase-1 signaling pathway25
Retraction notice to “Exploring the role of biologics in depression” [Cellular Signalling 98 (2022) 110409]24
Corrigendum to “Nintedanib improves bleomycin-induced pulmonary fibrosis by inhibiting the Clec7a/SPP1 pathway in interstitial macrophages” [Cellular Signalling, 2025 April, Volume 128, 111635]24
EOGT knockdown promotes ferroptosis and inhibits hepatocellular carcinoma proliferation by regulating SLC7A11 via HEY124
PDGFRB promotes dedifferentiation and pulmonary metastasis through rearrangement of cytoskeleton under hypoxic microenvironment in osteosarcoma24
Hsa_circ_0048764 facilitates the progression of non-small cell lung cancer by targeting miR-1178-3p/HMGA1 axis24
The biological clock gene PER2 promotes PANoptosis in oral squamous cell carcinoma by facilitating the formation of the Caspase-8/RIPK3/ASC complex24
Exosomal B7-H3 facilitates colorectal cancer angiogenesis and metastasis through AKT1/mTOR/VEGFA pathway24
SphK1 deficiency ameliorates the development of atherosclerosis by inhibiting the S1P/S1PR3/Rhoa/ROCK pathway24
CircRNA0007766 accelerates cancer progression via miR-34c-5p/cyclin D1 axis in adenocarcinoma of the esophagogastric junction (AEG)24
Understanding the impact of nuclear-localized GPCRs on cellular signalling24
METTL3 modulates bone Cancer pain via m6A-dependent JAK2/STAT3 activation in spinal astrocytes24
HSYA targets the ZBP1–166R site to inhibit MAVS signaling: A potential therapeutic strategy for cerebral ischemia-reperfusion injury23
Low-intensity pulsed ultrasound (LIPUS) promotes skeletal muscle regeneration by regulating PGC-1α/AMPK/GLUT4 pathways in satellite cells/myoblasts23
Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload23
Endoplasmic reticulum stress regulates intestinal motility in acute pancreatitis by regulating the expression and phosphorylation of nNOS through IRE1α/XBP1s-PI3K/Akt signaling axis23
ACVR1 mediates renal tubular EMT in kidney fibrosis via AKT activation23
Isoimperatorin down-regulates epithelial mesenchymal transition through modulating NF-κB signaling and CXCR4 expression in colorectal and hepatocellular carcinoma cells22
The Wnt signaling pathway plays a key role in regulating the pluripotent state of rbESCs and promoting their commitment to the primordial germ cell fate22
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy22
The emerging role of PANoptosis in viral infections disease22
mTOR potentiates senescent phenotypes and primary cilia formation after cisplatin-induced G2 arrest in retinal pigment epithelial cells22
Exploring the therapeutic potential of 4,4′-dimethoxychalcone: Inducing apoptosis in cancer cells via ER stress and autophagy disruption22
STEAP4 modulates cell proliferation and oxidative stress in benign prostatic hyperplasia22
Activation of SIRT3 by Tanshinone IIA ameliorates renal fibrosis by suppressing the TGF-β/TSP-1 pathway and attenuating oxidative stress22
MSTN gene knockout suppresses the activation of lung fibroblasts through the inhibition of the Smad/AKT signaling pathway, thereby ameliorating pulmonary fibrosis22
Histone H4K12 lactylation promotes malignancy progression in triple-negative breast cancer through SLFN5 downregulation22
ADAMTSL2 facilitates ACLY-mediated lipid metabolism in colorectal cancer by activating Notch signaling pathway22
The signaling pathways activated by ROR1 in cancer22
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p6222
CPT2-mediated fatty acid oxidation inhibits tumorigenesis and enhances sorafenib sensitivity via the ROS/PPARγ/NF-κB pathway in clear cell renal cell carcinoma22
Downregulation of NNMT affects trophoblast function via inhibiting COMP/CD36/ERK1/2 axis in recurrent spontaneous abortion22
Inhibition of ubiquitin-specific protease 7 ameliorates ferroptosis-mediated myocardial infarction by contrasting oxidative stress: An in vitro and in vivo analysis22
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis22
Vav1 accelerates Ras-driven lung cancer and modulates its tumor microenvironment.21
BDH1 regulates cardiomyocyte apoptosis and diabetic cardiomyopathy by modulating mitochondrial dynamics and attenuating oxidative stress21
Editorial Board21
A comprehensive evaluation of circ_0065214/ miR-188-3p/GPNMB axis in breast cancer21
LRP1 regulates GDNF secretion and perineural invasion in pancreatic cancer via PI3K/AKT signaling21
Crosstalk between hippo and Wnt pathways in intestinal stem cells regeneration21
Unraveling the role of the renin-angiotensin system in severe mental illnesses: An insight into psychopathology and cognitive deficits21
A computational biology approach to identify potential protein biomarkers and drug targets for sporadic amyotrophic lateral sclerosis21
ACSS3 protein macromolecule regulates glycolysis in keloid through Wnt/β-catenin signaling pathway: Bioinformatics, machine learning, and experimental validation21
METTL14-mediated N6-methyladenosine modification of TCP1 mRNA promotes acute myeloid leukemia progression21
TYROBP overexpression alters macrophage phenotype and enhances pancreatic cancer stemness through STAT3 and PKM2 signaling20
Evolving perspectives on lipid mediated cell-to-cell communication: The adenylyl cyclase signaling system20
Circ-AMOTL1 enhances cardiac fibrosis through binding with EIF4A3 and stabilizing MARCKS expression in diabetic cardiomyopathy20
Prolyl isomerase Pin1 promotes autophagy and cancer cell viability through activating FoxO3 signalling20
TNALP promotes epithelial oxidative stress and fibrosis via SIRT3-dependent mechanisms in tracheal injury20
Small extracellular vesicles from HO-1-modified bone marrow-derived mesenchymal stem cells attenuate ischemia-reperfusion injury after steatotic liver transplantation by suppressing ferroptosis via mi20
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma20
Aquaporin-5 facilitates liver regeneration following hepatectomy via ROS/GSDMD pathway20
Y-box binding protein 1: A critical target for understanding and treating cardiovascular disease19
CircINADL promotes nasopharyngeal carcinoma metastasis by inhibiting HuR ubiquitin degradation and disrupting the hippo signaling pathway19
Single-cell RNA sequencing reveals B cell dynamics and osteoclast activation in Talaromycosis-related bone destruction19
RORα inhibits proliferation and chemoresistance through AKR1A1-induced glucose and lipid reprogramming in gastric cancer19
RNA and protein degradation in the aging process19
An update on the molecular mechanism and pharmacological interventions for Ischemia-reperfusion injury by regulating AMPK/mTOR signaling pathway in autophagy19
Cell-type specific contribution of KLF4 to fibrotic nephropathy in tubular epithelium and fibroblast19
Human placental mesenchymal stromal cells alleviate intestinal oxidative damage in mice with graft-versus-host disease via CD73/adenosine/PI3K/Akt/GSK-3β axis19
Boldine prevents the inflammatory response of cardiac fibroblasts induced by SGK1-NFκB signaling pathway activation19
AMPK-mediated autophagy pathway activation promotes ΔFosB degradation to improve levodopa-induced dyskinesia19
Deciphering the relationship between caveolae-mediated intracellular transport and signalling events19
Lactate dehydrogenase B as a metabolism-related marker for immunotherapy in head and neck squamous cell carcinoma19
Acute myeloid leukemia cells induce senescence and adipogenic differentiation of mesenchymal stem cells in a tumor-supportive microenvironment at the same time19
miR-15a-5p enhances the malignant phenotypes of colorectal cancer cells through the STAT3/TWIST1 and PTEN/AKT signaling pathways by targeting SIRT419
ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation19
CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer19
Mst1 inhibition attenuates obesity cardiomyopathy via reversing FUNDC1-related mitophagy19
SARS-CoV-2 NSP16 promotes IL-6 production by regulating the stabilization of HIF-1α19
The trilateral crosstalk of TGF β1-ROS-Nrf2 axis in fibrosis: Decoding mechanistic networks for precision therapeutics19
DEAD-box protein 21 promotes renal fibrosis via p21-dependent cell cycle arrest in proximal tubular epithelial cells19
Corrigendum to “TET1 mediated m5C modification of RelB aggravates cerebral ischemia/reperfusion-induced neuroinflammation through regulating microglia polarization” [Cell Signal. 2024 Aug;120:111210]19
Study on the effects and mechanism of RRM2 on three gynecological malignancies19
LINC00426, a novel m6A-regulated long non-coding RNA, induces EMT in cervical cancer by binding to ZEB118
Lycium barbarum alleviates oxidative stress-induced ferroptosis and enhances mitophagy in intervertebral disc degeneration18
Fangchinoline inhibits metastasis and reduces inflammation-induced epithelial-mesenchymal transition by targeting the FOXM1-ADAM17 axis in hepatocellular carcinoma18
The roles of IDH2 and glutathione metabolism in cetuximab resistance in head and neck squamous cell carcinoma investigated by metabolomics and transcriptomics18
Hsa_circ_0000851 promotes PDK1/p-AKT-mediated cell proliferation and migration by regulating miR-1183 in triple-negative breast cancer18
Substrate stiffness modulates osteogenic and adipogenic differentiation of osteosarcoma through PIEZO1 mediated signaling pathway18
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression18
RIPK4 downregulation impairs Wnt3A-stimulated invasiveness via Wnt/β-catenin signaling in melanoma cells and tumor growth in vivo18
The role of RNA binding proteins in regulating oocyte maturation18
6-methylcoumarin/miR-122 suppresses hepatic Sortilin-mediated ApoB-100 secretion to attenuate aortic atherosclerosis18
MicroRNA-30c-5p arrests bladder cancer G2/M phase and suppresses its progression by targeting PRC1-mediated blocking of CDK1/Cyclin B1 axis18
VMP1 enhances autophagy to mitigate cardiac fibroblast activation and reduce post-ischemia-reperfusion fibrosis18
Functional delineation of the luminal epithelial microenvironment in breast using cell-based screening in combinatorial microenvironments18
The major vault protein integrates adhesion-driven signals to regulate collagen remodeling18
Epicatechin protects mice against OVA-induced asthma through inhibiting airway inflammation and modulating gut microbiota18
Gα13 signaling in the nervous system: Roles in neurodevelopment, stress responses, and neurological disorders18
Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine17
Reduced YAP1 and FOLR1 in gliomas predict better response to chemotherapeutics17
Corrigendum to “Numb/Notch/PLK1 signaling pathway mediated hyperglycemic memory in pancreatic cancer cell radioresistance and the therapeutic effects of metformin” [Cellular Signalling 93 (2022) 1102617
WITHDRAWN: Evolving perspectives on lipid mediated cell-to-cell communication: The adenylyl cyclase signaling system17
Mechanisms of constitutive and agonist-induced 5-HT2B internalization, persistent endosomal signaling and paradoxical regulation of agonist pharmacology17
Immunogenicity of cancer cells: An overview17
RETRACTED: Exploring the role of biologics in depression17
DDX24 promotes tumor progression by mediating hexokinase-1 induced glycolysis in gastric cancer17
Visfatin-induced upregulation of lipogenesis via EGFR/AKT/GSK3β pathway promotes breast cancer cell growth17
Deficiency of ATF2 retards senescence induced by replication stress and pamidronate in mouse jaw bone marrow stem cells17
Corrigendum to “O-GlcNAcylated c-Jun antagonizes ferroptosis via inhibiting GSH synthesis in liver cancer” [Cellular Signalling, 2019 Nov:63:109384. doi:10.1016/j.cellsig.2019.109384]17
The novel diarylurea derivative HPT-15 for potential treatment of triple-negative breast cancer via dual inhibition of the mTOR and MAPK pathways17
PRAP1 regulates colorectal cancer cell proliferation and ferroptosis through the Nrf2 signaling pathway17
Corrigendum to “RNA and protein degradation in the aging process” [Cellular Signalling 136 (2025) 112166]17
Unveiling the potential of proteomic and genetic signatures for precision therapeutics in lung cancer management17
Development of stemness-related signature to optimize prognosis prediction and identify XMD8-85 as a novel therapeutic compound for glioma17
CAFs-EVs-miR-6765-3p promotes malignant progression of colorectal cancer by regulating aerobic glycolysis mediated by the GNG7/mTOR pathway17
MTFR2 accelerates hepatocellular carcinoma mediated by metabolic reprogramming via the Akt signaling pathway17
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury17
Neutrophil extracellular traps promote gastric cancer cell metastasis via the NAT10-mediated N4-acetylcytidine modification of SMYD217
Migrasomes: Critical players in intercellular nanovesicle communication17
Corrigendum to “Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1” [Cellular Signalling, 28: (2016) 412–424]17
SIRT3 mitigates osteoarthritis by suppressing ferroptosis through activating AMPK signaling pathway17
Unraveling the molecular crosstalk and immune landscape between COVID-19 infections and ischemic heart failure comorbidity: New insights into diagnostic biomarkers and therapeutic approaches17
CDS1 deficiency promotes colorectal cancer progression by suppressing CDP-DAG-induced ferroptosis in MDSCs17
Features and functional mechanisms of super-enhancers in cardiovascular disorders, cancer, autoimmune diseases and neurodegenerative disorders17
Non-cyclic nucleotide EPAC1 activators suppress lipopolysaccharide-regulated gene expression, signalling and intracellular communication in differentiated macrophage-like THP-1 cells17
C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade17
NR2F2 and its contribution to lymph node metastasis in oral squamous cell carcinoma17
TRIM33 enhances the ubiquitination of TFRC to enhance the susceptibility of liver cancer cells to ferroptosis17
The role of arrestin-1 N-edge in rhodopsin binding16
Macrophage-conditioned medium enhances tunneling nanotube formation in breast cancer cells via PKC, Src, NF-κB, and p38 MAPK signaling16
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells16
Non-coding RNAs as mediators of epithelial to mesenchymal transition in metastatic colorectal cancers16
Cellular signaling and radioresistance in prostate cancer16
Silencing Adamts2 attenuates fibroblast-mediated fibrosis and promotes axonal regeneration in an in vitro model16
Aerobic plus resistance exercise attenuates skeletal muscle atrophy induced by dexamethasone through the HDAC4/FoxO3a pathway16
SHMT proteins: An emerging set of serine hydroxymethyltransferase in cancer16
YTHDF2 drives oral squamous cell carcinoma progression via m6A-dependent degradation of MTUS1/ATIP1 mRNA and mitochondrial dysregulation16
CTCF modulates adipocyte lipolysis via directly regulating the expression of Beclin 1 with the cooperation of PPARγ16
Overexpression of Dermokine-α enhances the proliferation and epithelial-mesenchymal transition of pancreatic tumor cells16
Hypoxia-induced HIF1A impairs sorafenib sensitivity in hepatocellular carcinoma through NSUN2-mediated stabilization of GDF1516
GPR91 mediates low shear stress-induced endothelial ferroptosis via EGR1-dependent GPX4 repression16
PacBio full-length transcriptome analysis reveals the role of tRNA-like structures in RNA processing16
Transcriptome sequencing analysis reveals miR-30c-5p promotes ferroptosis in cervical cancer and inhibits growth and metastasis of cervical cancer xenografts by targeting the METTL3/KRAS axis16
Targeting epithelial cell-derived TWIST1 alleviates allergic asthma16
APE1/Ref-1 redox function prevents VSMC phenotypic switching through KLF4 suppression16
Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway16
Targeting ferroptosis in cervical cancer: Mechanistic insights and therapeutic opportunities16
Glaucoma and the ocular renin-angiotensin-aldosterone system: Update on molecular signalling and treatment perspectives15
Gastric cancer-derived exosomal miR-196a-5p remodels the pre-metastatic niche for peritoneal dissemination15
Multi-omics reveals that QKI-mediated NIN exon 18 splicing drives breast cancer cell progression15
PINK1 deficiency alleviates bleomycin-induced pulmonary fibrosis in mice15
An integrative pan-cancer analysis of WWC family genes and functional validation in lung cancer15
Mst1 knockout and Nrf2 activation alleviate diabetic cardiomyopathy pathogenesis through autophagy modulation in type 2 diabetic mice15
Progress in targeted ferroptosis regulation and mechanism of action in hepatocellular carcinoma15
Cancer-associated fibroblasts-induced remodeling of tumor immune microenvironment via Jagged1 in glioma15
Anthocyanins from blueberry ameliorated arsenic-induced memory impairment, oxidative stress, and mitochondrial-biosynthesis imbalance in rat hippocampal neurons15
Identification and validation of ferroptosis-related genes for diabetic retinopathy15
M6A reader IGF2BP3 stabili1zes SLC7A11 to antagonize ferroptosis and promote gastric tumorigenesis15
Lipid metabolic reprogramming of CD8+ T cells in the tumor microenvironment15
Ewing sarcoma depends on C4orf48/NICOL, a NELL2 cofactor regulated by Hippo signaling15
Induction, amplification, and propagation of diabetic retinopathy-associated inflammatory cytokines between human retinal microvascular endothelial and Müller cells and in the mouse retina15
Tumor-suppressive role of miR-139-5p in angiogenesis and tumorigenesis of ovarian cancer: Based on GEO microarray analysis and experimental validation15
Ectopic viral integration Site-1 oncogene promotes NRAS pathway through epigenetic silencing of microRNA-124 in acute myeloid leukemia15
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice15
The cytopathic activity of cholera toxin requires a threshold quantity of cytosolic toxin15
Mammalian cleavage factor 25 targets KLF14 to inhibit hepatic stellate cell activation and liver fibrosis15
Lung cancer associated transcript 1 binds heat shock protein 90 to promote growth of hepatocellular carcinoma15
The FMO3/TMAO/HSP90β axis aggravates MAFLD by disrupting mitochondrial protein homeostasis15
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX115
IL-33/ST2 axis delays disc degeneration through PI3K/AKT-dependent regulation of nucleus pulposus cell proliferation and apoptosis15
Redox guardian or oncogenic driver? The dual roles of PRDX1 in tumorigenesis15
Akt-Axin1/TNKS-Tiam1-Rac1 mediates insulin-stimulated GLUT4 translocation in skeletal muscle cells15
LncRNA HMOX1 alleviates renal ischemia-reperfusion-induced ferroptotic injury via the miR-3587/HMOX1 axis15
LncRNA HOXA11-AS intercepts the POU2F2-mediated downregulation of SLC3A2 in osteoarthritis to suppress ferroptosis15
ALKBH5-mediated m6A modification of ID2 mRNA promotes choroidal neovascularization and subretinal fibrosis15
CD44-mediated copper accumulation drives Ly6Chi macrophages activation in ulcerative colitis15
Hijacking of GPCRs and RTKs by pathogens15
AKR1B1 bridges metabolic pathways and disease progression15
Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy15
CUEDC2 improves pyroptosis and kidney damage in diabetic kidney disease by inhibiting NLRP3 inflammasome activation15
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