Cellular Signalling

Papers
(The TQCC of Cellular Signalling is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Methylation and transcriptome analyses construct a prognostic model and reveal the suppressor role of VMO1 in lung adenocarcinoma107
MCC in the spotlight: Its dual role in signal regulation and oncogenesis89
Genome-scale CRISPR-Cas9 screening stratifies pancreatic cancer with distinct outcomes and immunotherapeutic efficacy64
PPP1CA promotes hepatocellular carcinoma progression in a YAP1-dependent way64
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage62
Exosomal circ_0008803 drives lung cancer cell migration and invasion via NF-κB activation58
METTL3 contributes to osimertinib resistance in non-small cell lung cancer cell lines by regulating CDC25A and AURKB mRNA stability56
Identification of the PP1 interactome in human dental pulp: Insights for regenerative strategies47
The role of microRNA-induced apoptosis in diverse radioresistant cancers45
TIGAR attenuates intervertebral disc degeneration via autophagy-mediated Keap1 degradation and Nrf2 nuclear translocation to suppress nucleus pulposus pyroptosis45
E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma44
ArfGAP3 regulates vesicle transport and glucose uptake in myoblasts43
Corrigendum to “GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway” [Cellular Signalin43
Comprehensive split TEV based protein-protein interaction screening reveals TAOK2 as a key modulator of Hippo signalling to limit growth41
Annexin A2 binds the 3′-UTR of H2AX mRNA and regulates histone-H2AX-derived hypoxia-inducible factor 1-alpha activation41
Activating transcription factor 6 protects against endothelial barrier dysfunction41
DSCR1–1 attenuates osteoarthritis-associated chondrocyte injury by regulating the CREB1/ALDH2/Wnt/β-catenin axis: An in vitro and in vivo study39
Targeting CDK12 rescues C/EBPβ-mediated platinum and PARP inhibitor resistance in ovarian cancer39
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor39
Oncolytic HSV-1 suppresses cell invasion through downregulating Sp1 in experimental glioblastoma39
KCa3.1 upregulation mediated by Ang II-induced JNK/AP-1 activation contributes to atrial fibrosis38
Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency37
S100P facilitates LUAD progression via PKA/c-Jun-mediated tumor-associated macrophage recruitment and polarization37
Effect of fibroblasts small- conductance Ca2+ -activated potassium channel subtype 2 (SK2) on myocardial fibrosis in pressure overload mouse36
Role of moesin and its phosphorylation in VE-cadherin expression and distribution in endothelial adherens junctions36
The main molecular mechanisms of ferroptosis and its role in chronic kidney disease36
Nuak kinase signaling in development and disease of the central nervous system35
Oncogenic crosstalk between ErbB2, nucleolin and Ras35
Caveolin-1 drives vasculogenic mimicry in lung adenocarcinoma through autophagy-mediated glycolytic reprogramming34
Paricalcitol attenuates oxidative stress and inflammatory response in the liver of NAFLD rats by regulating FOXO3a and NFκB acetylation34
IFI6 regulation of physiological functions in granulosa cells34
LncRNA Malat1 regulates iPSC-derived β-cell differentiation by targeting the miR-15b-5p/Ihh axis33
Corrigendum to “RBMS3 synergistically suppresses ovarian cancer progression at the post-transcriptional level by destabilizing ELAVL1 mRNA and inhibiting UPF1 methylation” [Cellular Signalling (2026) 33
Phosphorylation of mammalian mitochondrial EF-Tu by Fyn and c-Src kinases33
Mechanisms and therapeutic potential of multiple forms of programmed cell death in renal fibrosis33
A novel role of ADAMTS16 in renal fibrosis through activating TGF-β/Smad signaling33
The renin-angiotensin-aldosterone system: An old tree sprouts new shoots33
PPARG-FABP4 regulates PI3K/Akt pathway to promote lung cancer-associated macrophage endoplasmic reticulum stress-mediated CD36 expression and affects lung squamous cell carcinoma metastasis32
Circ_Mkrn2 facilitates the progression of atrial fibrillation via sponging miR-10b-5p32
Mechanical stress induced EndoMT in endothelial cells through PPARγ downregulation32
The miR-7 family: an evolutionary conservation and multifunctional miRNA family32
Editorial Board32
Uptake of ox-LDL by binding to LRP6 mediates oxidative stress-induced BMSCs senescence promoting obesity-related bone loss32
The KSR1/MEK/ERK signaling pathway promotes the progression of intrauterine adhesions32
HOXA1 promotes aerobic glycolysis and cancer progression in cervical cancer31
Primary cilium restricts TGF-β/SMAD signaling induced RIBEs in the co-culture model.31
Lactate induces oxidative phosphorylation in osteoblasts via Gpr81–Stat3 signaling31
GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway30
TSG101 overexpression enhances metastasis in oral squamous cell carcinoma through cell cycle regulation30
METTL3 promotes the growth and metastasis of pancreatic cancer by regulating the m6A modification and stability of E2F529
Hypoxia and ferroptosis29
DUSP2 affects bladder cancer prognosis by down-regulating MEK/ERK and P38 MAPK signaling pathways through PTPN728
METTL3-mediated m6A RNA modification promotes corneal neovascularization by upregulating the canonical Wnt pathway during HSV-1 infection28
Exploring m6A methylation in skin Cancer: Insights into molecular mechanisms and treatment28
Hsp70/CHIP E3 ligase complex triggers K149-linked ubiquitination and degradation of BEST1 mutants p.P233L and p.P346H, impairing chloride channel function and retinal integrity28
ACVR1 mediates renal tubular EMT in kidney fibrosis via AKT activation28
Exosomal B7-H3 facilitates colorectal cancer angiogenesis and metastasis through AKT1/mTOR/VEGFA pathway27
Pannexin1: A potential therapeutic target for multi-organ ischemic diseases27
Identification of resident progenitors labeled with Top2a responsible for proximal tubular regeneration in ischemia reperfusion-induced acute kidney injury27
Circadian clock regulation of myofibroblast fate27
The signaling pathways activated by ROR1 in cancer27
MSTN gene knockout suppresses the activation of lung fibroblasts through the inhibition of the Smad/AKT signaling pathway, thereby ameliorating pulmonary fibrosis26
The emerging significance of the METTL family as m6A-modified RNA methyltransferases in head and neck cancer26
Downregulation of NNMT affects trophoblast function via inhibiting COMP/CD36/ERK1/2 axis in recurrent spontaneous abortion26
Corrigendum to “Ginsenoside inhibits aerobic glycolysis in hepatocellular carcinoma through the hsa-miR-139-5p/AURKA axis” [Cellular Signalling 136 (2025) 112177]26
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy25
Corrigendum to “Hsp70/CHIP E3 ligase complex triggers K149-linked ubiquitination and degradation of BEST1 mutants p.P233L and p.P346H, impairing chloride channel function and retinal integrity” [Cellu25
DTX3L promotes renal cell carcinoma progression via ubiquitination and degradation of LATS225
The Wnt signaling pathway plays a key role in regulating the pluripotent state of rbESCs and promoting their commitment to the primordial germ cell fate25
The YAP1 and EPHA3 receptor tyrosine kinase axis regulates cellular plasticity and treatment response25
EOGT knockdown promotes ferroptosis and inhibits hepatocellular carcinoma proliferation by regulating SLC7A11 via HEY125
Low-intensity pulsed ultrasound (LIPUS) promotes skeletal muscle regeneration by regulating PGC-1α/AMPK/GLUT4 pathways in satellite cells/myoblasts25
G protein-coupled receptor kinase type 2 and β-arrestin2: Key players in immune cell functions and inflammation25
Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine25
HKDC1 promotes autophagy and proliferation in pancreatic adenocarcinoma through interaction with PARP1 and poly(ADP-ribosyl)ation25
CPT2-mediated fatty acid oxidation inhibits tumorigenesis and enhances sorafenib sensitivity via the ROS/PPARγ/NF-κB pathway in clear cell renal cell carcinoma24
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p6224
The super-enhancer regulatory gene SH2D1A promotes the progression of T cell acute lymphoblastic leukemia by activating CHI3L224
HSYA targets the ZBP1–166R site to inhibit MAVS signaling: A potential therapeutic strategy for cerebral ischemia-reperfusion injury24
NCAPG promotes epithelial-mesenchymal transition through SIP-dependent ubiquitination regulation of β-catenin in hepatocellular carcinoma24
Endoplasmic reticulum stress regulates intestinal motility in acute pancreatitis by regulating the expression and phosphorylation of nNOS through IRE1α/XBP1s-PI3K/Akt signaling axis24
NOX4 alleviates breast cancer cell aggressiveness by co-ordinating mitochondrial turnover through PGC1α/Drp1 axis24
Promoting the proliferation of osteoarthritis chondrocytes by resolvin D1 regulating the NLRP3/caspase-1 signaling pathway24
ACSL4 coordinates metabolic and cell cycle reprogramming to promote endometrial cancer progression24
RETRACTED: Exploring the role of astrocytic dysfunction and AQP4 in depression24
Sustained systemic inflammation increases autophagy and induces EMT/fibrotic changes in mouse liver cells: Protection by melatonin23
PDCD4 exacerbates myocardial ischemia-reperfusion injury via AKT-mediated apoptosis23
Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload23
SphK1 deficiency ameliorates the development of atherosclerosis by inhibiting the S1P/S1PR3/Rhoa/ROCK pathway23
Zika virus NS1 suppresses VE-cadherin via hsa-miR-29b-3p/DNMT3b/MMP-9 pathway in human brain microvascular endothelial cells23
Isoimperatorin down-regulates epithelial mesenchymal transition through modulating NF-κB signaling and CXCR4 expression in colorectal and hepatocellular carcinoma cells23
Hsa_circ_0048764 facilitates the progression of non-small cell lung cancer by targeting miR-1178-3p/HMGA1 axis22
Retraction notice to “Exploring the role of biologics in depression” [Cellular Signalling 98 (2022) 110409]22
CircRNA0007766 accelerates cancer progression via miR-34c-5p/cyclin D1 axis in adenocarcinoma of the esophagogastric junction (AEG)22
PDGFRB promotes dedifferentiation and pulmonary metastasis through rearrangement of cytoskeleton under hypoxic microenvironment in osteosarcoma22
The roles of IDH2 and glutathione metabolism in cetuximab resistance in head and neck squamous cell carcinoma investigated by metabolomics and transcriptomics22
Crosstalk between hippo and Wnt pathways in intestinal stem cells regeneration22
B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells22
Corrigendum to “Nintedanib improves bleomycin-induced pulmonary fibrosis by inhibiting the Clec7a/SPP1 pathway in interstitial macrophages” [Cellular Signalling, 2025 April, Volume 128, 111635]22
Activation of SIRT3 by Tanshinone IIA ameliorates renal fibrosis by suppressing the TGF-β/TSP-1 pathway and attenuating oxidative stress22
METTL3 modulates bone Cancer pain via m6A-dependent JAK2/STAT3 activation in spinal astrocytes22
Editorial Board22
Aquaporin-5 facilitates liver regeneration following hepatectomy via ROS/GSDMD pathway22
The biological clock gene PER2 promotes PANoptosis in oral squamous cell carcinoma by facilitating the formation of the Caspase-8/RIPK3/ASC complex22
STEAP4 modulates cell proliferation and oxidative stress in benign prostatic hyperplasia22
Potential role of Hematopoietic PBX-Interacting Protein (HPIP) in trophoblast fusion and invasion: Implications in pre-eclampsia pathogenesis22
Understanding the impact of nuclear-localized GPCRs on cellular signalling22
mTOR potentiates senescent phenotypes and primary cilia formation after cisplatin-induced G2 arrest in retinal pigment epithelial cells22
TYROBP overexpression alters macrophage phenotype and enhances pancreatic cancer stemness through STAT3 and PKM2 signaling22
Boldine prevents the inflammatory response of cardiac fibroblasts induced by SGK1-NFκB signaling pathway activation21
The emerging role of PANoptosis in viral infections disease21
The role of RNA binding proteins in regulating oocyte maturation21
Y-box binding protein 1: A critical target for understanding and treating cardiovascular disease21
Mst1 inhibition attenuates obesity cardiomyopathy via reversing FUNDC1-related mitophagy21
Hsa_circ_0000851 promotes PDK1/p-AKT-mediated cell proliferation and migration by regulating miR-1183 in triple-negative breast cancer21
Epicatechin protects mice against OVA-induced asthma through inhibiting airway inflammation and modulating gut microbiota21
Substrate stiffness modulates osteogenic and adipogenic differentiation of osteosarcoma through PIEZO1 mediated signaling pathway21
RNA and protein degradation in the aging process21
Acute myeloid leukemia cells induce senescence and adipogenic differentiation of mesenchymal stem cells in a tumor-supportive microenvironment at the same time21
6-methylcoumarin/miR-122 suppresses hepatic Sortilin-mediated ApoB-100 secretion to attenuate aortic atherosclerosis20
AMPK-mediated autophagy pathway activation promotes ΔFosB degradation to improve levodopa-induced dyskinesia20
TNALP promotes epithelial oxidative stress and fibrosis via SIRT3-dependent mechanisms in tracheal injury20
Corrigendum to “TET1 mediated m5C modification of RelB aggravates cerebral ischemia/reperfusion-induced neuroinflammation through regulating microglia polarization” [Cell Signal. 2024 Aug;120:111210]20
A comprehensive evaluation of circ_0065214/ miR-188-3p/GPNMB axis in breast cancer20
Fangchinoline inhibits metastasis and reduces inflammation-induced epithelial-mesenchymal transition by targeting the FOXM1-ADAM17 axis in hepatocellular carcinoma20
Exploring the therapeutic potential of 4,4′-dimethoxychalcone: Inducing apoptosis in cancer cells via ER stress and autophagy disruption20
Vav1 accelerates Ras-driven lung cancer and modulates its tumor microenvironment.20
SARS-CoV-2 NSP16 promotes IL-6 production by regulating the stabilization of HIF-1α19
CircINADL promotes nasopharyngeal carcinoma metastasis by inhibiting HuR ubiquitin degradation and disrupting the hippo signaling pathway19
Deciphering the relationship between caveolae-mediated intracellular transport and signalling events19
miR-15a-5p enhances the malignant phenotypes of colorectal cancer cells through the STAT3/TWIST1 and PTEN/AKT signaling pathways by targeting SIRT419
Histone H4K12 lactylation promotes malignancy progression in triple-negative breast cancer through SLFN5 downregulation19
ADAMTSL2 facilitates ACLY-mediated lipid metabolism in colorectal cancer by activating Notch signaling pathway19
Small extracellular vesicles from HO-1-modified bone marrow-derived mesenchymal stem cells attenuate ischemia-reperfusion injury after steatotic liver transplantation by suppressing ferroptosis via mi19
FGD5-AS1/miR-5590-3p/PINK1 induces Lenvatinib resistance in hepatocellular carcinoma19
CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer19
LINC00426, a novel m6A-regulated long non-coding RNA, induces EMT in cervical cancer by binding to ZEB119
Lactate dehydrogenase B as a metabolism-related marker for immunotherapy in head and neck squamous cell carcinoma19
An update on the molecular mechanism and pharmacological interventions for Ischemia-reperfusion injury by regulating AMPK/mTOR signaling pathway in autophagy19
RORα inhibits proliferation and chemoresistance through AKR1A1-induced glucose and lipid reprogramming in gastric cancer19
MicroRNA-30c-5p arrests bladder cancer G2/M phase and suppresses its progression by targeting PRC1-mediated blocking of CDK1/Cyclin B1 axis19
DEAD-box protein 21 promotes renal fibrosis via p21-dependent cell cycle arrest in proximal tubular epithelial cells19
Prolyl isomerase Pin1 promotes autophagy and cancer cell viability through activating FoxO3 signalling19
Evolving perspectives on lipid mediated cell-to-cell communication: The adenylyl cyclase signaling system19
Single-cell RNA sequencing reveals B cell dynamics and osteoclast activation in Talaromycosis-related bone destruction19
Functional delineation of the luminal epithelial microenvironment in breast using cell-based screening in combinatorial microenvironments19
The major vault protein integrates adhesion-driven signals to regulate collagen remodeling19
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression19
BDH1 regulates cardiomyocyte apoptosis and diabetic cardiomyopathy by modulating mitochondrial dynamics and attenuating oxidative stress19
Human placental mesenchymal stromal cells alleviate intestinal oxidative damage in mice with graft-versus-host disease via CD73/adenosine/PI3K/Akt/GSK-3β axis18
ACSS3 protein macromolecule regulates glycolysis in keloid through Wnt/β-catenin signaling pathway: Bioinformatics, machine learning, and experimental validation18
Inhibition of ubiquitin-specific protease 7 ameliorates ferroptosis-mediated myocardial infarction by contrasting oxidative stress: An in vitro and in vivo analysis18
ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation18
Lycium barbarum alleviates oxidative stress-induced ferroptosis and enhances mitophagy in intervertebral disc degeneration18
IL-10 inhibits osteoclast differentiation and osteolysis through MEG3/IRF8 pathway18
Circ-AMOTL1 enhances cardiac fibrosis through binding with EIF4A3 and stabilizing MARCKS expression in diabetic cardiomyopathy18
A computational biology approach to identify potential protein biomarkers and drug targets for sporadic amyotrophic lateral sclerosis18
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis18
LRP1 regulates GDNF secretion and perineural invasion in pancreatic cancer via PI3K/AKT signaling18
METTL14-mediated N6-methyladenosine modification of TCP1 mRNA promotes acute myeloid leukemia progression18
Unraveling the role of the renin-angiotensin system in severe mental illnesses: An insight into psychopathology and cognitive deficits18
RIPK4 downregulation impairs Wnt3A-stimulated invasiveness via Wnt/β-catenin signaling in melanoma cells and tumor growth in vivo18
Non-cyclic nucleotide EPAC1 activators suppress lipopolysaccharide-regulated gene expression, signalling and intracellular communication in differentiated macrophage-like THP-1 cells17
C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade17
GPR91 mediates low shear stress-induced endothelial ferroptosis via EGR1-dependent GPX4 repression17
SIRT5-mediated desuccinylation prevents mitochondrial dysfunction in alveolar epithelial cells senescence and pulmonary fibrosis17
YTHDF2 drives oral squamous cell carcinoma progression via m6A-dependent degradation of MTUS1/ATIP1 mRNA and mitochondrial dysregulation17
Corrigendum to “Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1” [Cellular Signalling, 28: (2016) 412–424]17
The trilateral crosstalk of TGF β1-ROS-Nrf2 axis in fibrosis: Decoding mechanistic networks for precision therapeutics17
PRAP1 regulates colorectal cancer cell proliferation and ferroptosis through the Nrf2 signaling pathway17
Mammalian cleavage factor 25 targets KLF14 to inhibit hepatic stellate cell activation and liver fibrosis17
VMP1 enhances autophagy to mitigate cardiac fibroblast activation and reduce post-ischemia-reperfusion fibrosis17
Visfatin-induced upregulation of lipogenesis via EGFR/AKT/GSK3β pathway promotes breast cancer cell growth17
Mechanisms of constitutive and agonist-induced 5-HT2B internalization, persistent endosomal signaling and paradoxical regulation of agonist pharmacology17
The FMO3/TMAO/HSP90β axis aggravates MAFLD by disrupting mitochondrial protein homeostasis17
MTFR2 accelerates hepatocellular carcinoma mediated by metabolic reprogramming via the Akt signaling pathway17
Corrigendum to “Numb/Notch/PLK1 signaling pathway mediated hyperglycemic memory in pancreatic cancer cell radioresistance and the therapeutic effects of metformin” [Cellular Signalling 93 (2022) 1102617
Study on the effects and mechanism of RRM2 on three gynecological malignancies17
Corrigendum to “O-GlcNAcylated c-Jun antagonizes ferroptosis via inhibiting GSH synthesis in liver cancer” [Cellular Signalling, 2019 Nov:63:109384. doi:10.1016/j.cellsig.2019.109384]17
The novel diarylurea derivative HPT-15 for potential treatment of triple-negative breast cancer via dual inhibition of the mTOR and MAPK pathways17
Unveiling the potential of proteomic and genetic signatures for precision therapeutics in lung cancer management17
Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine17
Unraveling the molecular crosstalk and immune landscape between COVID-19 infections and ischemic heart failure comorbidity: New insights into diagnostic biomarkers and therapeutic approaches17
Migrasomes: Critical players in intercellular nanovesicle communication17
Immunogenicity of cancer cells: An overview17
Lung cancer associated transcript 1 binds heat shock protein 90 to promote growth of hepatocellular carcinoma17
Features and functional mechanisms of super-enhancers in cardiovascular disorders, cancer, autoimmune diseases and neurodegenerative disorders17
Corrigendum to “RNA and protein degradation in the aging process” [Cellular Signalling 136 (2025) 112166]16
The role of FPR3 in remodeling the immune microenvironment and lung metastasis of colon adenocarcinoma16
Non-coding RNAs as mediators of epithelial to mesenchymal transition in metastatic colorectal cancers16
Macrophage-conditioned medium enhances tunneling nanotube formation in breast cancer cells via PKC, Src, NF-κB, and p38 MAPK signaling16
Neutrophil extracellular traps promote gastric cancer cell metastasis via the NAT10-mediated N4-acetylcytidine modification of SMYD216
Anthocyanins from blueberry ameliorated arsenic-induced memory impairment, oxidative stress, and mitochondrial-biosynthesis imbalance in rat hippocampal neurons16
WITHDRAWN: Evolving perspectives on lipid mediated cell-to-cell communication: The adenylyl cyclase signaling system16
RETRACTED: Exploring the role of biologics in depression16
Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway16
Hypoxia-induced HIF1A impairs sorafenib sensitivity in hepatocellular carcinoma through NSUN2-mediated stabilization of GDF1516
Cellular signaling and radioresistance in prostate cancer16
AKR1B1 bridges metabolic pathways and disease progression16
Transcriptome sequencing analysis reveals miR-30c-5p promotes ferroptosis in cervical cancer and inhibits growth and metastasis of cervical cancer xenografts by targeting the METTL3/KRAS axis16
Reduced YAP1 and FOLR1 in gliomas predict better response to chemotherapeutics16
CAFs-EVs-miR-6765-3p promotes malignant progression of colorectal cancer by regulating aerobic glycolysis mediated by the GNG7/mTOR pathway16
Targeting epithelial cell-derived TWIST1 alleviates allergic asthma16
Cancer-associated fibroblasts-induced remodeling of tumor immune microenvironment via Jagged1 in glioma16
M6A reader IGF2BP3 stabili1zes SLC7A11 to antagonize ferroptosis and promote gastric tumorigenesis16
Overexpression of Dermokine-α enhances the proliferation and epithelial-mesenchymal transition of pancreatic tumor cells16
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury16
Aerobic plus resistance exercise attenuates skeletal muscle atrophy induced by dexamethasone through the HDAC4/FoxO3a pathway16
SIRT3 mitigates osteoarthritis by suppressing ferroptosis through activating AMPK signaling pathway16
CDS1 deficiency promotes colorectal cancer progression by suppressing CDP-DAG-induced ferroptosis in MDSCs16
PacBio full-length transcriptome analysis reveals the role of tRNA-like structures in RNA processing15
NR2F2 and its contribution to lymph node metastasis in oral squamous cell carcinoma15
SHMT proteins: An emerging set of serine hydroxymethyltransferase in cancer15
Identification and validation of ferroptosis-related genes for diabetic retinopathy15
Ferroptosis-related LINC02535/has-miR-30c-5p/EIF2S1 axis as a novel prognostic biomarker involved in immune infiltration and progression of PDAC15
Tumor-suppressive role of miR-139-5p in angiogenesis and tumorigenesis of ovarian cancer: Based on GEO microarray analysis and experimental validation15
Extracellular vesicle-induced cyclic AMP signaling15
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells15
TRIM33 enhances the ubiquitination of TFRC to enhance the susceptibility of liver cancer cells to ferroptosis15
CTCF modulates adipocyte lipolysis via directly regulating the expression of Beclin 1 with the cooperation of PPARγ15
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX115
CUEDC2 improves pyroptosis and kidney damage in diabetic kidney disease by inhibiting NLRP3 inflammasome activation15
The role of acetaldehyde dehydrogenase 2 in the pathogenesis of liver diseases15
Development of stemness-related signature to optimize prognosis prediction and identify XMD8-85 as a novel therapeutic compound for glioma15
The role of arrestin-1 N-edge in rhodopsin binding15
Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy15
Targeting ferroptosis in cervical cancer: Mechanistic insights and therapeutic opportunities15
Deficiency of ATF2 retards senescence induced by replication stress and pamidronate in mouse jaw bone marrow stem cells15
DDX24 promotes tumor progression by mediating hexokinase-1 induced glycolysis in gastric cancer15
LncRNA HMOX1 alleviates renal ischemia-reperfusion-induced ferroptotic injury via the miR-3587/HMOX1 axis15
STNM1 in human cancers: role, function and potential therapy sensitizer15
SYK and ZAP70 kinases in autoimmunity and lymphoid malignancies14
PINK1 deficiency alleviates bleomycin-induced pulmonary fibrosis in mice14
ALKBH5-mediated m6A modification of ID2 mRNA promotes choroidal neovascularization and subretinal fibrosis14
Progress in targeted ferroptosis regulation and mechanism of action in hepatocellular carcinoma14
HDAC1 inhibits beige adipocyte-mediated thermogenesis through histone crotonylation of Pgc1a/Ucp114
Redox guardian or oncogenic driver? The dual roles of PRDX1 in tumorigenesis14
ADSC exosomes improve high glucose induced fibroblast oxidative stress injury and accelerate DFU wound healing via regulating Keap1/Nrf2 axis14
Promoter A1312C mutation leads to microRNA-7 downregulation in human non-small cell lung cancer14
Akt-Axin1/TNKS-Tiam1-Rac1 mediates insulin-stimulated GLUT4 translocation in skeletal muscle cells14
Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc14
The cytopathic activity of cholera toxin requires a threshold quantity of cytosolic toxin14
Induction, amplification, and propagation of diabetic retinopathy-associated inflammatory cytokines between human retinal microvascular endothelial and Müller cells and in the mouse retina14
Unveiling the bidirectional role of MMP9: A key player in kidney injury14
FOXC1 promotes EMT and colorectal cancer progression by attracting M2 macrophages via the TGF-β/Smad2/3/snail pathway14
A novel role of follicular fluid chemokine CCL21 in promoting porcine oocyte in vitro maturation through activating ERK1/2 signaling pathway14
Ewing sarcoma depends on C4orf48/NICOL, a NELL2 cofactor regulated by Hippo signaling14
Hijacking of GPCRs and RTKs by pathogens14
FGF10 attenuates allergic airway inflammation in asthma by inhibiting PI3K/AKT/NF-κB pathway14
An integrative pan-cancer analysis of WWC family genes and functional validation in lung cancer14
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