OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Autoimmunity is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Safety of biologic immunosuppressants in pregnant women with immune-mediated inflammatory diseases	412
Janus kinase inhibition prevents autoimmune diabetes in LEW.1WR1 rats	190
ATP-binding cassette G1 membrane transporter-mediated cholesterol efflux capacity influences coronary atherosclerosis and cardiovascular risk in Rheumatoid Arthritis	155
GILZ regulates type I interferon release and sequesters STAT1	148
HNF4α, SP1 and c-myc are master regulators of CNS autoimmunity	130
Advances in SLE classification criteria	126
The universal effects of low-dose interleukin-2 across 13 autoimmune diseases in a basket clinical trial	117
Autoimmune associated HLAs and T cell autoantigens exhibit common patterns across several autoimmune diseases	106
Breach of tolerance versus burden of bile acids: Resolving the conundrum in the immunopathogenesis and natural history of primary biliary cholangitis	105
Disease activity in patients with immune-mediated inflammatory diseases after SARS-CoV-2 vaccinations	104
Differences in innate immune cell populations distinguish autoimmune from herpesvirus-associated encephalitis	99
Autoreactivity to self-antigens LL37 and ADAMTSL5 influences the clinical response to risankizumab in psoriatic patients	93
Editorial Board	93
Immunological and fibrotic profiling in the NOD.c3c4 murine model of autoimmune cholangitis	91
Ectopic CD4+ T cells in choroid plexus mediate neuropsychiatric lupus symptoms in mice via interferon-γ induced microglia activation	86
Tfh cell-derived small extracellular vesicles exacerbate the severity of collagen-induced arthritis by enhancing B-cell responses	83
Global and regional epidemiology of psoriatic arthritis in patients with psoriasis: A comprehensive systematic analysis and modelling study	76
Lupus nephritis: new progress in diagnosis and treatment	75
Post-translationally modified proteins bind and activate complement with implications for cellular uptake and autoantibody formation	71
Anti-annexin A4 antibody as a biomarker for desquamative interstitial pneumonia	71
Editorial Board	70
Genetic and transcriptomic analyses support a switch to lytic phase in Epstein Barr virus infection as an important driver in developing Systemic Lupus Erythematosus	63
Editorial Board	56
Editorial Board	52
Autoantibodies against a subunit of mitochondrial respiratory chain complex I in inclusion body myositis	52

Glycobiology of psoriasis: A review	50
Sunscreen use associated with elevated prevalence of anti-nuclear antibodies in U.S. adults	50
Identification of the central tolerance checkpoint for autoreactive proteinase 3+ B cells in human bone marrow	49
Antigenic mimicry – The key to autoimmunity in immune privileged organs	48
Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations	48
Cellular communication network factor 3 contributes to the pathological process of rheumatoid arthritis through promoting cell senescence and osteoclastogenesis in the joint	47
Targeting macrophages with phosphatidylserine-rich liposomes as a potential antigen-specific immunotherapy for type 1 diabetes	46
LAT1 enables T cell activation under inflammatory conditions	45
Mitochondrial dysfunction is a potential key mechanism for atherosclerosis predisposition in patients with systemic lupus erythematosus	45
Intracellular virus sensor MDA5 mutation develops autoimmune myocarditis and nephritis	44
Assessment of the 2023 ACR/EULAR antiphospholipid syndrome classification criteria in a Chinese cohort: Impact on clinical practice	39
Whole blood transcriptome identifies interferon-regulated genes as key drivers in thrombotic primary antiphospholipid syndrome	38
Earlier vs. later time period of COVID-19 infection and emergent autoimmune signs, symptoms, and serologies	37
FAPI PET/CT for tracking disease trajectory in myositis-related interstitial lung disease	37
Interferon signatures fuel B cell hyperactivity and plasmablast expansion in systemic lupus erythematosus	37
The complement system and human autoimmune diseases	36
Editorial Board	35
The role of gut flora-driven Th cell responses in preclinical rheumatoid arthritis	34
Clinical targeted treatment in Sjogren's disease: A systematic literature review for an evidence-based medicine approach	33
Renal and vascular outcomes in patients with isolated antiphospholipid syndrome nephropathy	32
Differential changes in the gut microbiota between extrinsic and intrinsic atopic dermatitis	32
Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis	31
Pregnancy-related complications in systemic lupus erythematosus	30
Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels in primary antiphospholipid syndrome. The multicenter ATHERO-APS study	29
External and internal exposome as triggers of biological signalling in systemic sclerosis – A narrative synthesis	29
The aryl hydrocarbon receptor in immune regulation and autoimmune pathogenesis	29
Single-cell sequencing of the retina shows that LDHA regulates pathogenesis of autoimmune uveitis	29
Antigen-specific immune reactions by expanded CD8+ T cell clones from HLA-B*27-positive patients with spondyloarthritis	29
Familial patterns of alopecia areata: A systematic review and meta-analysis	28
Peripheral immune profiling highlights a dynamic role of low-density granulocytes in myasthenia gravis	28
Impact of BNT162b2 mRNA anti-SARS-CoV-2 vaccine on interferon-alpha production by plasmacytoid dendritic cells and autoreactive T cells in patients with systemic lupus erythematosus: The COVALUS proje	28
Long-term efficacy and safety of colchicine and anti-IL-1 blockers in FMF: results from the Eurofever multicenter observational study	27
Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosus	27
Clinical utility of measuring CD4+ T follicular cells in patients with immune dysregulation	27
LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis	26
Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target	26
Interferon signature in giant cell arteritis aortitis	26
Autoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review	26
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice	26
Autoimmune hepatitis after SARS-CoV-2 vaccine: New-onset or flare-up?	25
Coronavirus disease 2019, vaccination against coronavirus and immunoglobulin A-mediated diseases: systematic literature review	24
Environmental exposures as risk factors for idiopathic inflammatory myopathies	24
Does COVID-19 impact the prevalence of myositis specific antibodies in the Netherlands? A comparative nationwide study	24
Recent advances in cutaneous lupus	24
Functional metagenomic analysis reveals potential inflammatory triggers associated with genetic risk for autoimmune disease	24
Evaluation of the mycophenolate mofetil–rituximab combination in systemic sclerosis: a French retrospective multicenter study (MycRiSSc)	23
Alternate splicing converts human CD137 from costimulatory to immunosuppressive function	23
Temporal trajectories and DMARD therapy retention of rheumatoid arthritis patients with different autoimmune and inflammatory comorbidity profiles: a retrospective analysis	23
Altered lipid metabolism in synovial fibroblasts of individuals at risk of developing rheumatoid arthritis	23
T cell aging as a risk factor for autoimmunity	22

Editorial Board	22
Autoantibodies against α-synuclein inhibit its aggregation and cytotoxicity	22
Extracellular vesicle autoantibodies	21
Pro-fibrotic effect of the susceptible gene PCSK5 in vascular fibrosis of Takayasu arteritis via TGF-β and SMAD3 signaling pathway activation	21
High T-cell response rate after COVID-19 vaccination in belimumab and rituximab recipients	21
Identifying the genetic association between systemic lupus erythematosus and the risk of autoimmune liver diseases	21
Interleukin 17-producing C-C motif chemokine receptor 6 + conventional CD4+ T cells are arthritogenic in an animal model of spondyloarthritis	21
High-content multimodal analysis supports the IL-7/IL-7 receptor axis as a relevant therapeutic target in primary Sjögren's syndrome	21
Gut microbiota in systemic lupus erythematosus: A fuse and a solution	20
RNA-binding protein hnRNP UL1 binds κB sites to attenuate NF-κB-mediated inflammation	20
Acquired susceptibility to autoimmune diseases in pediatric patients with Escherichia coli infection: A population-matched retrospective cohort study	20
Significance of anti-transcobalamin receptor antibodies in cutaneous arteritis revealed by proteome-wide autoantibody screening	20
Anti-DNA antibody-targeted D-peptide nanoparticles ameliorate lupus nephritis in MRL/lpr mice	20
Interleukin-15 is a hair follicle immune privilege guardian	19
Preliminary safety and efficacy of relmacabtagene autoleucel (relma-cel) in adults with moderately to severely active systemic lupus erythematosus: a phase I dose-escalation study	19
2023 International Consensus Guidance for the use of Tripterygium Wilfordii Hook F in the treatment of active rheumatoid arthritis	19
Methotrexate and low-dose prednisone in idiopathic retroperitoneal fibrosis: a randomised clinical trial	19
Application of laboratory models for sarcoidosis research	18
A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile	18
JAK inhibitors in refractory juvenile rheumatic diseases: Efficacy, tolerance and type-I interferon profiling, a single center retrospective study	18
Pin1 maintains the effector program of pathogenic Th17 cells in autoimmune neuroinflammation	18
Autoimmune diseases and the risk of bladder cancer: A Mendelian randomization analysis	18
T follicular helper cells in autoimmune diseases	18
Immunosuppression induces regression of fibrosis in primary biliary cholangitis with moderate-to-severe interface hepatitis	18
Suppression of YTHDF2 attenuates autoimmune hepatitis by expansion of myeloid-derived suppressor cells	17
Natural IgG protects against early dissemination of vesicular stomatitis virus	17
CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus	17
Genetic and pharmacological targeting of GSDMD ameliorates systemic inflammation in macrophage activation syndrome	17
Multi-omics study reveals different pathogenesis of the generation of skin lesions in SLE and IDLE patients	17
Association between age groups and relapse of type 1 autoimmune pancreatitis: a large-scale retrospective cohort study	17
Altered glucose metabolism in B cells: Implications for the pathogenesis and treatment of autoimmune diseases	17
Cytokine producing B-cells and their capability to polarize macrophages in giant cell arteritis	17
VEXAS syndrome: A newly identified X-Linked hematoinflammatory disorder – A comprehensive overview of its genetic, molecular, inflammatory, and clinical landscape	17
Comprehensive description of adult-onset Still's disease after COVID-19 vaccination	17
Acute-type acquired hemophilia A after COVID-19 mRNA vaccine administration: A new disease entity?	17
Accelerated waning of immune responses to a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases	17
Fecal microbiota transplantation in the treatment of systemic lupus erythematosus: What we learnt from the explorative clinical trial	17
Corrigendum to “Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies” [J. Autoimmun. 126 (2022) 102774]	16
PD1+ innate lymphoid cells 3 predict JAK-dependent inflammation in rheumatoid arthritis	16
Poorer survival for patients with inflammatory arthritis treated with immune checkpoint inhibitors for melanoma	16
Treatment of mixed connective tissue disease: A multicenter retrospective study	16
A cluster of type II interferon-regulated genes associates with disease activity in patients with systemic lupus erythematosus	16
PD-1 antibody interactions with Fc gamma receptors enable PD-1 agonism to inhibit T cell activation – therapeutic implications for autoimmunity	16
Neutrophil activation biomarker pentraxin 3 for diagnosis and monitoring of macrophage activation syndrome occurrence in adult-onset Still's disease	16
Amelioration of immunoglobulin A vasculitis by suppression of the pathological expansion of T follicular helper 17 cells	16
Leukocytoclastic vasculitis (cutaneous small-vessel vasculitis) after COVID-19 vaccination	16
Outcome and prognosis of isolated carotid vasculitis	16
Developmental drugs for sarcoidosis	16
Cognitive dysfunction in SLE: An understudied clinical manifestation	16
Elevated unphosphorylated STAT1 and IRF9 in T and B cells of primary sjögren's syndrome: Novel biomarkers for disease activity and subsets	16
Regulatory T cells effectively downregulate the autoimmune anti-MPO response and ameliorate anti-MPO induced glomerulonephritis in mice	16
Chimeric antigen receptor T cell therapy: a new frontier therapeutic landscape in autoimmune diseases	16
Monoclonal antibodies from B cells of patients with anti-MDA5 antibody-positive dermatomyositis directly stimulate interferon gamma production	16
Comparative effectiveness of preventive treatment with dimethyl fumarate-loaded solid lipid nanoparticles and oral dimethyl fumarate in a mouse model of multiple sclerosis	15
Sonic hedgehog promotes synovial inflammation and articular damage through p38 mitogen-activated protein kinase signaling in experimental arthritis	15
Repeated immunization with ATRA-containing liposomal adjuvant transdifferentiates Th17 cells to a Tr1-like phenotype	15
Pathogenicity of functionally activated PD-1+CD8+ cells and counterattacks by muscular PD-L1 through IFNγ in myositis	15
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis	15
Autoimmune hepatitis following COVID-19 vaccination	15
Extracellular microRNAs induce dendritic cell-dependent joint inflammation and potentiate osteoclast differentiation via TLR7/8 engagement	15
Elderly-onset systemic sclerosis defines a distinct clinical subset: analysis from the SPRING registry of the Italian Society for Rheumatology	15