Neuron

Article	Citations
Microglia states and nomenclature: A field at its crossroads	806
Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology	383
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo	292
ALS Genetics: Gains, Losses, and Implications for Future Therapies	258
White matter aging drives microglial diversity	249
Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research	244
The different autophagy degradation pathways and neurodegeneration	230
The neurobiology of long COVID	225
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration	198
Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease	196
Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer’s disease	196
Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines	192
Behavior needs neural variability	183
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells	183
Behaviorally consequential astrocytic regulation of neural circuits	180
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia	178
High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies	176
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias	174
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia	173
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology	158
Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis	157
Single-Cell Sequencing of Brain Cell Transcriptomes and Epigenomes	157
20 years of the default mode network: A review and synthesis	156
Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain	151
Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer’s Disease	149

Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions	149
Gender bias in academia: A lifetime problem that needs solutions	148
Virus exposure and neurodegenerative disease risk across national biobanks	147
The population doctrine in cognitive neuroscience	145
Brain-behavior correlations: Two paths toward reliability	145
Single cortical neurons as deep artificial neural networks	142
Transcriptional Programs of Circuit Assembly in the Drosophila Visual System	128
Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions	128
Orthogonal representations for robust context-dependent task performance in brains and neural networks	127
Opposing Influence of Top-down and Bottom-up Input on Excitatory Layer 2/3 Neurons in Mouse Primary Visual Cortex	126
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components	126
Internal senses of the vagus nerve	126
Area Postrema Cell Types that Mediate Nausea-Associated Behaviors	125
Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury	120
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease	118
The mouse prefrontal cortex: Unity in diversity	118
Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice	118
Enhancer viruses for combinatorial cell-subclass-specific labeling	117
IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice	115
In vitro neurons learn and exhibit sentience when embodied in a simulated game-world	113
Neural circuits of social behaviors: Innate yet flexible	110
Unraveling circuits of visual perception and cognition through the superior colliculus	109
The emergence and influence of internal states	108
Programming axonal mitochondrial maintenance and bioenergetics in neurodegeneration and regeneration	107
Sleep—A brain-state serving systems memory consolidation	106
Continuous Whole-Body 3D Kinematic Recordings across the Rodent Behavioral Repertoire	105
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes	104
A mechanism for inter-areal coherence through communication based on connectivity and oscillatory power	104
Regional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network	102
Replay bursts in humans coincide with activation of the default mode and parietal alpha networks	102
Spontaneous activity in developing thalamic and cortical sensory networks	101
Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans	101
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum	101
Fast Recurrent Processing via Ventrolateral Prefrontal Cortex Is Needed by the Primate Ventral Stream for Robust Core Visual Object Recognition	99
Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain	99
Hyperscanning: Beyond the Hype	98
Regional Aβ-tau interactions promote onset and acceleration of Alzheimer’s disease tau spreading	98
A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo	97
Medial and orbital frontal cortex in decision-making and flexible behavior	97
Mechanisms of memory under stress	96
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease	94
Behavioral, Physiological, and Neural Signatures of Surprise during Naturalistic Sports Viewing	93
Alternating sources of perisomatic inhibition during behavior	93
Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases	92
Large-Scale 3D Two-Photon Imaging of Molecularly Identified CA1 Interneuron Dynamics in Behaving Mice	92
Human and mouse trigeminal ganglia cell atlas implicates multiple cell types in migraine	92
Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease	91
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors	91
Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome	91
Spatial goal coding in the hippocampal formation	90

Mediodorsal and Ventromedial Thalamus Engage Distinct L1 Circuits in the Prefrontal Cortex	90
Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon	89
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation	89
A Disinhibitory Circuit for Contextual Modulation in Primary Visual Cortex	89
Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin	88
Preexisting hippocampal network dynamics constrain optogenetically induced place fields	87
Differential Emergence and Stability of Sensory and Temporal Representations in Context-Specific Hippocampal Sequences	87
An Open Resource for Non-human Primate Optogenetics	87
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory	86
The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection	86
Hypothalamus-habenula potentiation encodes chronic stress experience and drives depression onset	84
CellExplorer: A framework for visualizing and characterizing single neurons	84
Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2	82
Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia	82
Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable	81
Expanding evolutionary neuroscience: insights from comparing variation in behavior	80
Periaqueductal gray/dorsal raphe dopamine neurons contribute to sex differences in pain-related behaviors	79
RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury	79
Cochlear neural degeneration disrupts hearing in background noise by increasing auditory cortex internal noise	78
Frequency of theta rhythm is controlled by acceleration, but not speed, in running rats	78
Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms	78
Brain microvasculature has a common topology with local differences in geometry that match metabolic load	77
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD	76
Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis	76
Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy	76
Reconstruction of the Hypothalamo-Neurohypophysial System and Functional Dissection of Magnocellular Oxytocin Neurons in the Brain	76
Cell-type-specific binocular vision guides predation in mice	75
Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety	75
Microbiota-brain interactions: Moving toward mechanisms in model organisms	74
No consolidation without representation: Correspondence between neural and psychological representations in recent and remote memory	74
What is the dynamical regime of cerebral cortex?	74
A cellular taxonomy of the adult human spinal cord	73
Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions	72
Emergence of Neuronal Diversity during Vertebrate Brain Development	72
Optimal anticipatory control as a theory of motor preparation: A thalamo-cortical circuit model	72
Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury	72
Extracting the dynamics of behavior in sensory decision-making experiments	72
Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease	72
Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas	72
Make war not love: The neural substrate underlying a state-dependent switch in female social behavior	72
A direct lateral entorhinal cortex to hippocampal CA2 circuit conveys social information required for social memory	71
Entorhinal and ventromedial prefrontal cortices abstract and generalize the structure of reinforcement learning problems	71
A photoswitchable GPCR-based opsin for presynaptic inhibition	71
Spatial modulation of hippocampal activity in freely moving macaques	70
Sleep Promotes Downward Firing Rate Homeostasis	69
Direct neuronal reprogramming: Fast forward from new concepts toward therapeutic approaches	69
Principles of large-scale neural interactions	69
Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells	69
Divergent brainstem opioidergic pathways that coordinate breathing with pain and emotions	69
Flexible rerouting of hippocampal replay sequences around changing barriers in the absence of global place field remapping	69
Brain rhythms define distinct interaction networks with differential dependence on anatomy	68
The cellular and molecular basis of somatosensory neuron development	68
A cerebellar-thalamocortical pathway drives behavioral context-dependent movement initiation	68
A Platform for Brain-wide Volumetric Functional Ultrasound Imaging and Analysis of Circuit Dynamics in Awake Mice	68
Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons	67
Rapid suppression and sustained activation of distinct cortical regions for a delayed sensory-triggered motor response	67
Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons	67
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis	67
Interoception of breathing and its relationship with anxiety	67
HepaCAM controls astrocyte self-organization and coupling	66
Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior	65
Sub-second Dopamine and Serotonin Signaling in Human Striatum during Perceptual Decision-Making	65
How does hemispheric specialization contribute to human-defining cognition?	65
Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain	65
Microglia in multiple sclerosis: Protectors turn destroyers	65
Signatures of rapid plasticity in hippocampal CA1 representations during novel experiences	64
An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury	64
Sensory Discrimination of Blood and Floral Nectar by Aedes aegypti Mosquitoes	64
Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury	63
Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation	63
NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming	63
Synaptic correlates of associative fear memory in the lateral amygdala	63
A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking	63
General anesthesia globally synchronizes activity selectively in layer 5 cortical pyramidal neurons	63
Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems	63
Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors	63
Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells	62
A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice	62
Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing	62
Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH	62

Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions	62
Single-trial decoding of movement intentions using functional ultrasound neuroimaging	61
Relocation of an Extrasynaptic GABAA Receptor to Inhibitory Synapses Freezes Excitatory Synaptic Strength and Preserves Memory	61
Metabolic Regulation of Neocortical Expansion in Development and Evolution	61
Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior	60
Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9	60
A Visual Circuit Related to the Nucleus Reuniens for the Spatial-Memory-Promoting Effects of Light Treatment	60
Subcircuits of Deep and Superficial CA1 Place Cells Support Efficient Spatial Coding across Heterogeneous Environments	59
A dopamine gradient controls access to distributed working memory in the large-scale monkey cortex	59
Hippocampal ripples and their coordinated dialogue with the default mode network during recent and remote recollection	59
Blood-based biomarkers for Alzheimer’s disease: Current state and future use in a transformed global healthcare landscape	59
Decoding Cellular Mechanisms for Mechanosensory Discrimination	59
The advent of fear conditioning as an animal model of post-traumatic stress disorder: Learning from the past to shape the future of PTSD research	58
Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking	58
Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition	58
Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain	58
Dynamin is primed at endocytic sites for ultrafast endocytosis	58
A Functional Topographic Map for Spinal Sensorimotor Reflexes	57
Visual intracortical and transthalamic pathways carry distinct information to cortical areas	57
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel	57
A functionally ordered visual feature map in the Drosophila brain	57
Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking	57
GABAergic neuronal IL-4R mediates T cell effect on memory	56
Highly selective brain-to-gut communication via genetically defined vagus neurons	56
A central mechanism of analgesia in mice and humans lacking the sodium channel NaV1.7	56
Local feedback inhibition tightly controls rapid formation of hippocampal place fields	56
Differential Synaptic Input to External Globus Pallidus Neuronal Subpopulations In Vivo	56
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience	56
Over and above frequency: Gamma oscillations as units of neural circuit operations	55
Extrinsic control and intrinsic computation in the hippocampal CA1 circuit	55
NDNF interneurons in layer 1 gain-modulate whole cortical columns according to an animal’s behavioral state	55
Neuroblastoma: When differentiation goes awry	55
NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior	55
A prefrontal network integrates preferences for advance information about uncertain rewards and punishments	55
Synchronized cluster firing, a distinct form of sensory neuron activation, drives spontaneous pain	54
Cellular activity in insular cortex across seconds to hours: Sensations and predictions of bodily states	54
CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities	54
Presynaptic store-operated Ca2+ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress	54
Neocortex saves energy by reducing coding precision during food scarcity	54
Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility	54
Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK	53
Synaptic-like axo-axonal transmission from striatal cholinergic interneurons onto dopaminergic fibers	53
Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier	53
In vivo endocannabinoid dynamics at the timescale of physiological and pathological neural activity	53
Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement	53
Sensory and Behavioral Components of Neocortical Signal Flow in Discrimination Tasks with Short-Term Memory	53
RNA modulates physiological and neuropathological protein phase transitions	53
Planning in the brain	53
Visual thalamocortical mechanisms of waking state-dependent activity and alpha oscillations	53
Human cells and networks of pain: Transforming pain target identification and therapeutic development	53
Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor	53
A functional subdivision within the somatosensory system and its implications for pain research	52
Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats	52
Locus coeruleus anchors a trisynaptic circuit controlling fear-induced suppression of feeding	51
Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction	51
Neural state space alignment for magnitude generalization in humans and recurrent networks	51
Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2	51
Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes	51
Hippocampal-amygdala memory circuits govern experience-dependent observational fear	51
Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator	51
The anterior cingulate cortex directs exploration of alternative strategies	51
A neural code for egocentric spatial maps in the human medial temporal lobe	51
Oxytocin receptor is not required for social attachment in prairie voles	51
Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons	50
Mitophagy in the basolateral amygdala mediates increased anxiety induced by aversive social experience	50
Rethinking retrosplenial cortex: Perspectives and predictions	50
Unveiling the abstract format of mnemonic representations	50
Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury	50
Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse	50
Periphery signals generated by Piezo-mediated stomach stretch and Neuromedin-mediated glucose load regulate the Drosophila brain nutrient sensor	50
A locus coeruleus to dentate gyrus noradrenergic circuit modulates aversive contextual processing	50
High-density single-unit human cortical recordings using the Neuropixels probe	50
Reward signals in the cerebellum: Origins, targets, and functional implications	49
Transcriptional and functional divergence in lateral hypothalamic glutamate neurons projecting to the lateral habenula and ventral tegmental area	49
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices	49
Functional neuroimaging in psychiatry and the case for failing better	48
Joint representation of working memory and uncertainty in human cortex	48
Machine learning dissection of human accelerated regions in primate neurodevelopment	48
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4	48
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation	48
CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells	47
Multisensory coding of angular head velocity in the retrosplenial cortex	47
An activity-dependent determinant of synapse elimination in the mammalian brain	47
Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease	47
Neural activity in the mouse claustrum in a cross-modal sensory selection task	47
A Presynaptic Perspective on Transport and Assembly Mechanisms for Synapse Formation	47
Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals	46
Promises and challenges of human computational ethology	46
Optogenetic fUSI for brain-wide mapping of neural activity mediating collicular-dependent behaviors	46
Chromatin-mediated alternative splicing regulates cocaine-reward behavior	46
Interneuronal exchange and functional integration of synaptobrevin via extracellular vesicles	46
Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel	46
5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis	46
Laboratory models of post-traumatic stress disorder: The elusive bridge to translation	45
Not so spontaneous: Multi-dimensional representations of behaviors and context in sensory areas	45