Neuron

Article	Citations
The Bidirectional Relationship of Depression and Inflammation: Double Trouble	951
Microglia states and nomenclature: A field at its crossroads	581
Astrocyte Crosstalk in CNS Inflammation	471
Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology	312
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury	295
COVID-19 and the Chemical Senses: Supporting Players Take Center Stage	261
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo	246
White matter aging drives microglial diversity	229
ALS Genetics: Gains, Losses, and Implications for Future Therapies	228
Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research	208
Somatotopic Organization and Intensity Dependence in Driving Distinct NPY-Expressing Sympathetic Pathways by Electroacupuncture	197
The different autophagy degradation pathways and neurodegeneration	182
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration	181
How Can Hearing Loss Cause Dementia?	178
Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer’s disease	172
Artificial Neural Networks for Neuroscientists: A Primer	167
Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines	166
High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies	164
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells	163
The neurobiology of long COVID	163
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia	163
Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation	162
Behavior needs neural variability	161
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia	160
Behaviorally consequential astrocytic regulation of neural circuits	158

Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease	153
Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis	148
Single-Cell Sequencing of Brain Cell Transcriptomes and Epigenomes	147
A Primer on Motion Capture with Deep Learning: Principles, Pitfalls, and Perspectives	143
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology	143
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias	140
Ultrasound Technologies for Imaging and Modulating Neural Activity	140
Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer’s Disease	138
Imaging Neurotransmitter and Neuromodulator Dynamics In Vivo with Genetically Encoded Indicators	136
Map Making: Constructing, Combining, and Inferring on Abstract Cognitive Maps	132
Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain	128
Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions	128
Transcriptional Programs of Circuit Assembly in the Drosophila Visual System	125
Magnetoelectric Materials for Miniature, Wireless Neural Stimulation at Therapeutic Frequencies	123
Single cortical neurons as deep artificial neural networks	123
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components	123
The population doctrine in cognitive neuroscience	121
Deep Reinforcement Learning and Its Neuroscientific Implications	120
Plasticity and Spontaneous Activity Pulses in Disused Human Brain Circuits	119
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes	119
Gender bias in academia: A lifetime problem that needs solutions	116
A Distributed Neural Code in the Dentate Gyrus and in CA1	115
Virus exposure and neurodegenerative disease risk across national biobanks	114
Area Postrema Cell Types that Mediate Nausea-Associated Behaviors	113
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease	111
Ultra-slow Oscillations in fMRI and Resting-State Connectivity: Neuronal and Vascular Contributions and Technical Confounds	110
Brain-behavior correlations: Two paths toward reliability	110
Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis	110
Opposing Influence of Top-down and Bottom-up Input on Excitatory Layer 2/3 Neurons in Mouse Primary Visual Cortex	109
Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury	109
Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism	108
Enhancer viruses for combinatorial cell-subclass-specific labeling	106
Comprehensive Dual- and Triple-Feature Intersectional Single-Vector Delivery of Diverse Functional Payloads to Cells of Behaving Mammals	106
Integrative Benchmarking to Advance Neurally Mechanistic Models of Human Intelligence	103
Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions	103
Neural circuits of social behaviors: Innate yet flexible	102
Unraveling circuits of visual perception and cognition through the superior colliculus	102
Fovea-like Photoreceptor Specializations Underlie Single UV Cone Driven Prey-Capture Behavior in Zebrafish	102
IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice	99
Orthogonal representations for robust context-dependent task performance in brains and neural networks	99
Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice	99
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes	97
Arousal Modulates Retinal Output	97
Regional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network	96
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum	96
G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD	96
Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer’s Disease	96
A mechanism for inter-areal coherence through communication based on connectivity and oscillatory power	95
The mouse prefrontal cortex: Unity in diversity	95
Neural Trajectories in the Supplementary Motor Area and Motor Cortex Exhibit Distinct Geometries, Compatible with Different Classes of Computation	95

In vitro neurons learn and exhibit sentience when embodied in a simulated game-world	94
Internal senses of the vagus nerve	94
Spontaneous activity in developing thalamic and cortical sensory networks	94
An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques	94
Continuous Whole-Body 3D Kinematic Recordings across the Rodent Behavioral Repertoire	93
Replay bursts in humans coincide with activation of the default mode and parietal alpha networks	92
Hyperscanning: Beyond the Hype	91
VTA Glutamate Neuron Activity Drives Positive Reinforcement Absent Dopamine Co-release	91
Behavioral, Physiological, and Neural Signatures of Surprise during Naturalistic Sports Viewing	91
Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome	90
The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor	89
An Integrated Index: Engrams, Place Cells, and Hippocampal Memory	89
Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator	89
Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain	88
Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases	88
Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans	87
A Neural Network for Wind-Guided Compass Navigation	87
Slow Drift of Neural Activity as a Signature of Impulsivity in Macaque Visual and Prefrontal Cortex	87
Disrupted Place Cell Remapping and Impaired Grid Cells in a Knockin Model of Alzheimer's Disease	87
Recent Advances in Electrical Neural Interface Engineering: Minimal Invasiveness, Longevity, and Scalability	86
Spatial goal coding in the hippocampal formation	85
Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin	85
The emergence and influence of internal states	85
VTA Glutamatergic Neurons Mediate Innate Defensive Behaviors	85
Mediodorsal and Ventromedial Thalamus Engage Distinct L1 Circuits in the Prefrontal Cortex	85
Extraction of Distinct Neuronal Cell Types from within a Genetically Continuous Population	85
A Disinhibitory Circuit for Contextual Modulation in Primary Visual Cortex	84
Fast Recurrent Processing via Ventrolateral Prefrontal Cortex Is Needed by the Primate Ventral Stream for Robust Core Visual Object Recognition	83
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation	83
An Open Resource for Non-human Primate Optogenetics	83
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory	83
Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon	83
A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo	82
SNAREopathies: Diversity in Mechanisms and Symptoms	82
Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia	81
Large-Scale 3D Two-Photon Imaging of Molecularly Identified CA1 Interneuron Dynamics in Behaving Mice	81
Astrocytes Control Sensory Acuity via Tonic Inhibition in the Thalamus	81
Programming axonal mitochondrial maintenance and bioenergetics in neurodegeneration and regeneration	81
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease	81
Alternating sources of perisomatic inhibition during behavior	80
The Parabrachial Nucleus Directly Channels Spinal Nociceptive Signals to the Intralaminar Thalamic Nuclei, but Not the Amygdala	80
Preexisting hippocampal network dynamics constrain optogenetically induced place fields	80
Differential Emergence and Stability of Sensory and Temporal Representations in Context-Specific Hippocampal Sequences	80
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors	79
20 years of the default mode network: A review and synthesis	79
A M/EEG-fMRI Fusion Primer: Resolving Human Brain Responses in Space and Time	78
Neural Sequences as an Optimal Dynamical Regime for the Readout of Time	77
Regional Aβ-tau interactions promote onset and acceleration of Alzheimer’s disease tau spreading	77
Precise Holographic Manipulation of Olfactory Circuits Reveals Coding Features Determining Perceptual Detection	77
Short-Term Plasticity at Hippocampal Mossy Fiber Synapses Is Induced by Natural Activity Patterns and Associated with Vesicle Pool Engram Formation	77
Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation	76
TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells	75
Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2	75
Frequency of theta rhythm is controlled by acceleration, but not speed, in running rats	75
The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection	75
Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable	75
Mechanisms of memory under stress	74
Sleep—A brain-state serving systems memory consolidation	73
Cochlear neural degeneration disrupts hearing in background noise by increasing auditory cortex internal noise	73
Human and mouse trigeminal ganglia cell atlas implicates multiple cell types in migraine	73
Two Brain Pathways Initiate Distinct Forward Walking Programs in Drosophila	72
What Is the Relationship between Pain and Emotion? Bridging Constructs and Communities	72
Medial and orbital frontal cortex in decision-making and flexible behavior	72
Mesoscopic Imaging: Shining a Wide Light on Large-Scale Neural Dynamics	72
Reconstruction of the Hypothalamo-Neurohypophysial System and Functional Dissection of Magnocellular Oxytocin Neurons in the Brain	71
Orchestrating Opiate-Associated Memories in Thalamic Circuits	71
Periaqueductal gray/dorsal raphe dopamine neurons contribute to sex differences in pain-related behaviors	71
Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas	70
A photoswitchable GPCR-based opsin for presynaptic inhibition	69
No consolidation without representation: Correspondence between neural and psychological representations in recent and remote memory	69
Cell-type-specific binocular vision guides predation in mice	69
CellExplorer: A framework for visualizing and characterizing single neurons	68
Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury	68
Hypothalamus-habenula potentiation encodes chronic stress experience and drives depression onset	67
Microbiota-brain interactions: Moving toward mechanisms in model organisms	67
What is the dynamical regime of cerebral cortex?	67
Expanding evolutionary neuroscience: insights from comparing variation in behavior	67
Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease	67
Sleep Promotes Downward Firing Rate Homeostasis	66
A cerebellar-thalamocortical pathway drives behavioral context-dependent movement initiation	66

Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy	66
A Platform for Brain-wide Volumetric Functional Ultrasound Imaging and Analysis of Circuit Dynamics in Awake Mice	66
Brain rhythms define distinct interaction networks with differential dependence on anatomy	66
Brain microvasculature has a common topology with local differences in geometry that match metabolic load	66
Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry	66
Optimal anticipatory control as a theory of motor preparation: A thalamo-cortical circuit model	65
Viral Vectors for Neural Circuit Mapping and Recent Advances in Trans-synaptic Anterograde Tracers	65
Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms	64
Visceral Mechano-sensing Neurons Control Drosophila Feeding by Using Piezo as a Sensor	64
Cooling of Medial Septum Reveals Theta Phase Lag Coordination of Hippocampal Cell Assemblies	64
RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury	64
The Dentate Gyrus Classifies Cortical Representations of Learned Stimuli	64
Cortical Observation by Synchronous Multifocal Optical Sampling Reveals Widespread Population Encoding of Actions	64
Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle	64
Spatial modulation of hippocampal activity in freely moving macaques	64
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD	63
A cellular taxonomy of the adult human spinal cord	63
Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety	62
Hippocampal Network Reorganization Underlies the Formation of a Temporal Association Memory	62
A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice	62
Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis	62
Emergence of Neuronal Diversity during Vertebrate Brain Development	62
A direct lateral entorhinal cortex to hippocampal CA2 circuit conveys social information required for social memory	61
Upgrading the Physiological Relevance of Human Brain Organoids	61
Extracting the dynamics of behavior in sensory decision-making experiments	61
Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation	61
Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans	61
Sub-second Dopamine and Serotonin Signaling in Human Striatum during Perceptual Decision-Making	61
Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface	61
HepaCAM controls astrocyte self-organization and coupling	61
Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing	60
How does hemispheric specialization contribute to human-defining cognition?	60
Sensory Discrimination of Blood and Floral Nectar by Aedes aegypti Mosquitoes	60
Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells	60
Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions	60
Rapid suppression and sustained activation of distinct cortical regions for a delayed sensory-triggered motor response	60
Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors	59
Interoception of breathing and its relationship with anxiety	59
Guidelines to Study and Develop Soft Electrode Systems for Neural Stimulation	59
Head Movements Control the Activity of Primary Visual Cortex in a Luminance-Dependent Manner	59
Synaptic correlates of associative fear memory in the lateral amygdala	59
Transient and Persistent Representations of Odor Value in Prefrontal Cortex	59
Cortical Representations of Conspecific Sex Shape Social Behavior	59
Encoding of 3D Head Orienting Movements in the Primary Visual Cortex	59
Flexible rerouting of hippocampal replay sequences around changing barriers in the absence of global place field remapping	58
Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH	58
Metabolic Regulation of Neocortical Expansion in Development and Evolution	58
Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems	58
Two Forms of Knowledge Representations in the Human Brain	58
Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons	58
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis	58
Entorhinal and ventromedial prefrontal cortices abstract and generalize the structure of reinforcement learning problems	58
Decoding Cellular Mechanisms for Mechanosensory Discrimination	58
Make war not love: The neural substrate underlying a state-dependent switch in female social behavior	57
Divergent brainstem opioidergic pathways that coordinate breathing with pain and emotions	57
Differential Synaptic Input to External Globus Pallidus Neuronal Subpopulations In Vivo	56
Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony	56
A Systematic Nomenclature for the Drosophila Ventral Nerve Cord	56
Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells	56
Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering	56
Single-trial decoding of movement intentions using functional ultrasound neuroimaging	55
Direct neuronal reprogramming: Fast forward from new concepts toward therapeutic approaches	55
Relocation of an Extrasynaptic GABAA Receptor to Inhibitory Synapses Freezes Excitatory Synaptic Strength and Preserves Memory	55
A Functional Topographic Map for Spinal Sensorimotor Reflexes	55
A Visual Circuit Related to the Nucleus Reuniens for the Spatial-Memory-Promoting Effects of Light Treatment	55
APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival	54
The Temporal Association Cortex Plays a Key Role in Auditory-Driven Maternal Plasticity	54
NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming	54
Subcircuits of Deep and Superficial CA1 Place Cells Support Efficient Spatial Coding across Heterogeneous Environments	54
Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior	54
Challenges for Large-Scale Cortical Interfaces	54
Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder	54
Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions	54
Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain	54
Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior	54
A dopamine gradient controls access to distributed working memory in the large-scale monkey cortex	54
Signatures of rapid plasticity in hippocampal CA1 representations during novel experiences	54
Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury	54
General anesthesia globally synchronizes activity selectively in layer 5 cortical pyramidal neurons	53
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel	53
Hippocampal ripples and their coordinated dialogue with the default mode network during recent and remote recollection	53
Human cells and networks of pain: Transforming pain target identification and therapeutic development	52
The cellular and molecular basis of somatosensory neuron development	52
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience	52
Sensory and Behavioral Components of Neocortical Signal Flow in Discrimination Tasks with Short-Term Memory	52
Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking	51
NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior	51
GABAergic neuronal IL-4R mediates T cell effect on memory	51
NDNF interneurons in layer 1 gain-modulate whole cortical columns according to an animal’s behavioral state	51
Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors	51
Cell-Type-Specific Outcome Representation in the Primary Motor Cortex	51
The advent of fear conditioning as an animal model of post-traumatic stress disorder: Learning from the past to shape the future of PTSD research	51
Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease	51
Cellular activity in insular cortex across seconds to hours: Sensations and predictions of bodily states	50
Piezo1-Mediated Ca2+ Activities Regulate Brain Vascular Pathfinding during Development	50