OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Molecular Neuroscience is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
rhEPO Upregulates the PPARγ Pathway in Long-term Cultured Primary Nerve Cells via PI3K/Akt to Delay Cell Senescence	64
Association of Telomere Length with Cognitive Impairment	59
Exploring the Correlation of Abnormal CXCL9 Expression with Immune Infiltration in Glioma and Patient Prognosis Based on TCGA and GTEx Databases	51
Early Alterations of PACAP and VIP Expression in the Female Rat Brain Following Spinal Cord Injury	50
Diagnosis and Drug Prediction of Parkinson’s Disease Based on Immune-Related Genes	41
Effect of Reactive EGCs on Intestinal Motility and Enteric Neurons During Endotoxemia	37
SIRT1-Enriched Exosomes Derived from Bone Marrow Mesenchymal Stromal Cells Alleviate Peripheral Neuropathy via Conserving Mitochondrial Function	31
Pharmacological Activation of GPR55 Improved Cognitive Impairment Induced by Lipopolysaccharide in Mice	29
A Novel Cuprotosis-Related lncRNA Signature Effectively Predicts Prognosis in Glioma Patients	26
Association Between Wnt Target Genes and Cortical Volumes in Alzheimer’s Disease	26
Serum Brain-Derived Neurotrophic Factor (BDNF) in COVID-19 Patients and its Association with the COVID-19 Manifestations	26
Genetic Analysis of Forty MLPA-Negative Duchenne Muscular Dystrophy Patients by Whole-Exome Sequencing	25
Predicting the Cognitive Ability of Young Women Using a New Feature Selection Algorithm	25
Association of Total Bilirubin with Motor Signs in Early Parkinson’s Disease in LRRK2 Variant Carriers	25
Effects of Treadmill Exercise on Social Behavior in Rats Exposed to Thimerosal with Respect to the Hippocampal Level of GluN1, GluN2A, and GluN2B	22
Fibroblast Growth Factor 2 Levels in Patients with Major Depressive Disorder: A Meta-analysis	22
NKCC1 to KCC2 mRNA Ratio in Schizophrenia and Its Psychopathology: a Case–Control Study	21
Investigation of the Relation between Epithelial Barrier Function and Autism Symptom Severity in Children with Autism Spectrum Disorder	21
A Comprehensive Investigation into the Association Between Mthfr C677t, A1298c, and Ace I/D Variants and Risk of Migraine: an Updated Meta-Analysis of Genetic Association Studies with Trial Sequential	21
Age-Dependent Regulation of Dendritic Spine Density and Protein Expression in Mir324 KO Mice	21
Neuron–Glia-Ratio-Like Approach Evidenced for Limited Variability and In-Aggregate Circadian Shifts in Cortical Cell-Specific Transcriptomes	20
Paeonol Ameliorates Cuprizone-Induced Hippocampal Demyelination and Cognitive Deficits through Inhibition of Oxidative and Inflammatory Events	19
Role of Senataxin in Amyotrophic Lateral Sclerosis	19
Gene Panel Sequencing Analysis Revealed a Strong Contribution of Rare Coding Variants to the Risk of Parkinson’s Disease in Sporadic Moroccan Patients	19
Upregulation of Src Family Tyrosine Kinases in the Rat Striatum by Adenosine A2A Receptors	19

Data-Independent Acquisition-Based Serum Proteomic Profiling of Adult Moyamoya Disease Patients Reveals the Potential Pathogenesis of Vascular Changes	18
Cytohesin-4 Upregulation in Glioma-Associated M2 Macrophages Is Correlated with Pyroptosis and Poor Prognosis	17
Histological and Top-Down Proteomic Analyses of the Visual Pathway in the Cuprizone Demyelination Model	17
CD93 is Associated with Glioma-related Malignant Processes and Immunosuppressive Cell Infiltration as an Inspiring Biomarker of Survivance	17
Critical Evaluation of Valproic Acid-Induced Rodent Models of Autism: Current and Future Perspectives	17
BDNF Val66Met Polymorphism: Suggested Genetic Involvement in Some Children with Learning Disorder	17
Primary and Secondary Microcephaly, Global Developmental Delay, and Seizure in Two Siblings Caused by a Novel Missense Variant in the ZNF335 Gene	16
Comprehensive Analysis of the miRNA-mRNA Pathological Regulatory Network of Intestinal CD4 + T Cells in Parkinson’s Disease	16
Urinary Proteome Analysis of Global Cerebral Ischemia–Reperfusion Injury Rat Model via Data-Independent Acquisition and Parallel Reaction Monitoring Proteomics	15
Vineland Adaptive Behavior Scale in a Cohort of Four ADNP Syndrome Patients Implicates Age-Dependent Developmental Delays with Increased Impact of Activities of Daily Living	14
First LIPA Mutational Analysis in Egyptian Patients Reveals One Novel Variant: Wolman Disease	14
Anti-Inflammatory Properties of KLS-13019: a Novel GPR55 Antagonist for Dorsal Root Ganglion and Hippocampal Cultures	13
DRAXIN as a Novel Diagnostic Marker to Predict the Poor Prognosis of Glioma Patients	13
Correction to: Microglia Activation in Retinal Ischemia Triggers Cytokine and Toll-Like Receptor Response	13
Tyrosinyl-amantadine: A New Amantadine Derivative With an Ameliorative Effect in a 6-OHDA Experimental Model of Parkinson’s Disease in Rats	13
Clinical and Molecular Spectrum of Muscular Dystrophies (MDs) with Intellectual Disability (ID): a Comprehensive Overview	13
Unique Ataxia-Oculomotor Apraxia 2 (AOA2) in Israel with Novel Variants, Atypical Late Presentation, and Possible Identification of a Poison Exon	13
FAS-mediated circRNA-miRNA-mRNA Crosstalk Network Regulates Immune Cell Infiltration in Cerebral Infarction	13
β-Hydroxybutyrate Alleviates Low Glucose–Induced Apoptosis via Modulation of ROS-Mediated p38 MAPK Signaling	13
Abnormal Transcript Levels of Cytokines Among Iranian COVID-19 Patients	13
Correction: Concurrent Assessment of Oxidative Stress and MT-ATP6 Gene Profiling to Facilitate Diagnosis of Autism Spectrum Disorder (ASD) in Tamil Nadu Population	13
Investigation of LncRNA PVT1 and MiR-21-5p Expression as Promising Novel Biomarkers for Autism Spectrum Disorder	13
Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Levels in Adolescent with Bipolar Disorder and Their Relationship with Metabolic Parameters	13
Spreading of Tau Protein Does Not Depend on Aggregation Propensity	12
Integrated Proteome and Phosphoproteome Analyses Reveal Early- and Late-Stage Protein Networks of Traumatic Brain Injury	12
MiR-106b-5p Attenuates Neuropathic Pain by Regulating the P2X4 Receptor in the Spinal Cord in Mice	12
Molecular Insights to the Wnt Signaling During Alzheimer’s Disorder: a Potential Target for Therapeutic Interventions	12
Effects of Meranzin Hydrate On the LncRNA–miRNA–mRNA Regulatory Network in the Hippocampus of a Rat Model of Depression	12
New Target of Oxidative Stress Regulation in Cochleae: Alternative Splicing of the p62/Sqstm1 Gene	12
Correction to: MicroRNA-351 Promotes the Proliferation and Invasion of Glioma Cells Through Downregulation of NAIF1	11
OECs Prevented Neuronal Cells from Apoptosis Partially Through Exosome-derived BDNF	11
Molecular Subgroup Classification in Alzheimer’s Disease by Transcriptomic Profiles	11
Psychobiotics: the Influence of Gut Microbiota on the Gut-Brain Axis in Neurological Disorders	11
Effects of Sevoflurane Exposure on Fetal Brain Development Using Cerebral Organoids	11
Identification of Key Genes Associated with Risk and Prognosis of Neuroblastoma	10
Untargeted Metabolomic Analysis Reveals the Metabolic Disturbances and Exacerbation of Oxidative Stress in the Cerebral Cortex of a BTBR Mouse Model of Autism	10
The Role of Single Nucleotide Polymorphisms of Monoamine Oxidase B, Dopamine D2 Receptor, and DOPA Decarboxylase Receptors Among Patients Treated for Parkinson’s Disease	10
Heparan Sulfate Proteoglycans (HSPGs) Serve as the Mediator Between Monomeric Tau and Its Subsequent Intracellular ERK1/2 Pathway Activation	10
RIT1 Promotes Glioma Proliferation and Invasion via the AKT/ERK/NF-ĸB Signaling Pathway	10
Gender-related Characteristics of Oxidative Stress Severity and Cognitive Impairment in Patients With Schizophrenia	10
Tumor Resident, B-Cell Receptor Chemical Characteristics Associated with Better Overall Survival for Neuroblastoma	10
The Effects of Methanol Extracts of Hyssopus officinalis on Model of Induced Glioblastoma Multiforme (GBM) in Rats	10
Network Biology Approaches to Uncover Therapeutic Targets Associated with Molecular Signaling Pathways from circRNA in Postoperative Cognitive Dysfunction Pathogenesis	10
Integrative Analysis of Inflammatory Response-Related Gene for Predicting Prognosis and Immunotherapy in Glioma	10
GM1 Reduced the Symptoms of Autism Spectrum Disorder by Suppressing α-Syn Through Activating Autophagy	10
The Role of Cystathionine-β-Synthase, H2S, and miRNA-377 in Hypoxic-Ischemic Encephalopathy: Insights from Human and Animal Studies	10
OXTR-Related Markers in Clinical Depression: a Longitudinal Case–Control Psychotherapy Study	9
MiR-574-5P, miR-1827, and miR-4429 as Potential Biomarkers for Schizophrenia	9
Correction: Age-Dependent Regulation of Dendritic Spine Density and Protein Expression in Mir324 KO Mice	9
Prosaposin Reduces α-Synuclein in Cells and Saposin C Dislodges it from Glucosylceramide-enriched Lipid Membranes	9

Discovering Common Pathogenic Mechanisms of COVID-19 and Parkinson Disease: An Integrated Bioinformatics Analysis	9
Sinomenine Attenuates Trimethyltin-Induced Cognitive Decline via Targeting Hippocampal Oxidative Stress and Neuroinflammation	9
Fetal Neuroprotective Mechanism of Maternal Magnesium Sulfate: Proteomic Analysis	8
Anti-Vascular Endothelial Growth Factor Therapy Abolishes Glioma-Associated Endothelial Cell-Induced Tumor Invasion	8
Particulate Matters Affecting lncRNA Dysregulation and Glioblastoma Invasiveness: In Silico Applications and Current Insights	8
Differential Expression of MicroRNAs and Predicted Drug Target in Amyotrophic Lateral Sclerosis	8
Knockdown of Rab7B, But Not of Rab7A, Which Antagonistically Regulates Oligodendroglial Cell Morphological Differentiation, Recovers Tunicamycin-Induced Defective Differentiation in FBD-102b Cells	8
Evaluating Gene Expression and Methylation Profiles of TCF4, MBP, and EGR1 in Peripheral Blood of Drug-Free Patients with Schizophrenia: Correlations with Psychopathology, Intelligence, and Cognitive	8
Assessment of Serum Hypoxia Biomarkers Pre- and Post-radiotherapy in Patients with Brain Tumors	8
Effect of Proinflammatory S100A9 Protein on Migration and Proliferation of Microglial Cells	8
Whole-Exome Sequencing Identified a Novel Mutation in RNF216 in a Family with Gordon Holmes Syndrome	8
Autophagy Dysfunction in ALS: from Transport to Protein Degradation	8
Intercellular Propagation and Aggregate Seeding of Mutant Ataxin-1	8
An Imbalance in the Pro/mature BDNF Ratio Occurs in Multiple Brain Regions During Normal Ageing in Wild-Type Mice	8
Lipopolysaccharide Exacerbates Ketamine-Induced Psychotic-Like Behavior, Oxidative Stress, and Neuroinflammation in Mice: Ameliorative Effect of Diosmin	8
Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia–Reperfusion Injury in Rats	8
CircRFX3 Up-regulates Its Host Gene RFX3 to Facilitate Tumorigenesis and Progression of Glioma	7
Hederagenin Upregulates PTPN1 Expression in Aβ-Stimulated Neuronal Cells, Exerting Anti-Oxidative Stress and Anti-Apoptotic Activities	7
Detecting Biomarkers of Alzheimer’s Disease Based on Multi-constrained Uncertainty-Aware Adaptive Sparse Multi-view Canonical Correlation Analysis	7
Normalization of HPA Axis, Cholinergic Neurotransmission, and Inhibiting Brain Oxidative and Inflammatory Dynamics Are Associated with The Adaptogenic-like Effect of Rutin Against Psychosocial Defeat	7
Ursolic Acid Enhances Myelin Repair in Adult Mice Brains and Stimulates Exhausted Oligodendrocyte Progenitors to Remyelinate	7
Journal of Molecular Neuroscience (JOMN)—Special Issue European Society for Neurochemistry (ESN) First Virtual Conference, May 2021	7
MiR-3918 Inhibits Tumorigenesis of Glioma via Targeting EGFR to Regulate PI3K/AKT and ERK Pathways	7
Activation of Lateral Parabrachial Nucleus (LPBn) PACAP-Expressing Projection Neurons to the Bed Nucleus of the Stria Terminalis (BNST) Enhances Anxiety-like Behavior	7
IFN-γ Triggered IFITM2 Expression to Induce Malignant Phenotype in Elderly GBM	7
The Heterogeneity of Tumour-Associated Macrophages Contributes to the Recurrence and Outcomes of Glioblastoma Patients	7
AATF Competitively Interacts with Nuclear AIF and Inhibits Parthanatos of Neurons in dMCAO/R and OGD/R Models	7
Hippocampal Activated Microglia May Contribute to Blood–Brain Barrier Impairment and Cognitive Dysfunction in Post-Traumatic Stress Disorder-Like Rats	7
Comparative Study on the Exacerbating Effects of Casein-Rich vs. Gluten-Rich Diets on Biochemical-Induced Features in Rodent Model of Autism	7
Pulsed Electromagnetic Field Protects Against Brain Injury After Intracerebral Hemorrhage: Involvement of Anti-Inflammatory Processes and Hematoma Clearance via CD36	6
Circulating Non-coding RNAs as Potential Biomarkers for Ischemic Stroke: A Systematic Review	6
Whole-Transcriptome Analysis of Serum L1CAM-Captured Extracellular Vesicles Reveals Neural and Glycosylation Changes in Autism Spectrum Disorder	6
Reinforcing Interdisciplinary Collaborations to Unravel the Astrocyte “Calcium Code”	6
Transcriptomic Analyses of Neurotoxic Astrocytes Derived from Adult Triple Transgenic Alzheimer’s Disease Mice	6
Cortical VIP+ Interneurons in the Upper and Deeper Layers Are Transcriptionally Distinct	6
A Cocktail of Polyherbal Bioactive Compounds and Regular Mobility Training as Senolytic Approaches in Age-dependent Alzheimer’s: the In Silico Analysis, Lifestyle Intervention in Old Age	6
BMP4, SGSH, and SLC11A2 are Predicted to Be Biomarkers of Aging Associated with Programmed Cell Death	6
A Comprehensive Investigation of Risk Association Between the -786 T > C, + 884 G > A, VNTR, rs743506, rs3918226 of eNOS and Susceptibility of Migraine: A Updated Meta-Analysis Utilizing Trial S	6
Neuro-COVID-19 With or Without the Multisystem Inflammatory Syndrome (MIS-C): A Single-Center Study	6
Investigation of the Role of Induced Overexpression of the Isolated Secreted Klotho on the A-172 Human Glioblastoma Cells	6
Identify Biomarkers of Alzheimer's Disease Based on Multi-task Canonical Correlation Analysis and Regression Model	5
Distribution of PACAP and PAC1 Receptor in the Human Eye	5
GPCR Intracellular Loop Regulation of Beta-Arrestin-Mediated Endosomal Signaling Dynamics	5
Correction to: Evaluation of AQP4/TRPV4 Channel Co-expression, Microvessel Density, and its Association with Peritumoral Brain Edema in Intracranial Meningiomas	5
RNA Sequencing of Intraoperative Peritumoral Tissues Reveals Potential Pathways Involved in Glioma-Related Seizures	5
A Type 3 Gaucher-Like Disease Due To Saposin C Deficiency in Two Emirati Families Caused by a Novel Splice Site Variant in the PSAP Gene	5
Genotypic-Phenotypic Analysis, Metabolic Profiling and Clinical Correlations in Parkinson’s Disease Patients from Tamil Nadu Population, India	5
The Role of Post-Translational Modifications on the Structure and Function of Tau Protein	5
Correction to: Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport	5
Mitochondrial Dysfunction Contributes To Zinc-induced Neurodegeneration: a Link with NADPH Oxidase	5
Neuroprotective Efficacy of Fisetin Against VPA-Induced Autistic Neurobehavioral Alterations by Targeting Dysregulated Redox Homeostasis	5
Stat3-Induced lncRNA Kcnq1ot1 Regulates the Apoptosis of Neuronal Cells in Spinal Cord Injury	5
Integrated Analysis and Identification of CSF-Derived Risk miRNAs and Pivotal Genes in Multiple Sclerosis	5
Effects of Glycogen Synthase Kinase-3 Beta Gene Polymorphisms on the Plasma Concentration of Aripiprazole in Chinese Patients with Schizophrenia: A Preliminary Study	5
Components of Salvia miltiorrhiza and Panax notoginseng Protect Pericytes Against OGD/R-Induced Injury via Regulating the PI3K/AKT/mTOR and JNK/ERK/P38 Signaling Pathways	5
Massive Accumulation of Sphingomyelin Affects the Lysosomal and Mitochondria Compartments and Promotes Apoptosis in Niemann-Pick Disease Type A	5