OOIR: Observatory of International Research

Papers

(The TQCC of Environmental and Molecular Mutagenesis is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: the special case of molnupiravir	44
Permitted daily exposure limits for noteworthy N‐nitrosamines	42
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing	24
Quercetin mediated attenuation of cadmium‐induced oxidative toxicity and apoptosis of spermatogenic cells in caprine testes in vitro	19
Heavy metals modulate DNA compaction and methylation at CpG sites in the metal hyperaccumulator Arabidopsis halleri	19
AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations	18
In vitro cytotoxicity and genotoxicity of single and combined pesticides used by Bolivian farmers	18
Evaluation of the mutagenic effects of Molnupiravir and N4‐hydroxycytidine in bacterial and mammalian cells by HiFi sequencing	17
A comprehensive literature review and meta‐analysis of the prevalence of pan‐cancer BRCA mutations, homologous recombination repair gene mutations, and homologous recombination defic	17
The role of epigenetics in the reproductive toxicity of environmental endocrine disruptors	16
Differences in cell death in methionine versus cysteine depletion	14
Elevated urinary mutagenicity among those exposed to bituminous coal combustion emissions or diesel engine exhaust	10
Mutagenicity and carcinogenicity of combustion emissions are impacted more by combustor technology than by fuel composition: A brief review	10
In vitro genotoxicity of dibutyl phthalate on A549 lung cells at air–liquid interface in exposure concentrations relevant at workplaces	10
Recommendations for conducting the rodent erythrocyte Pig‐a assay: A report from the HESI GTTCPig‐a Workgroup	10
Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose	10
Dietary fat intake during early pregnancy is associated with cord blood DNA methylation at IGF2 and H19 genes in newborns	9
PacBio sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens	9
In vivo genotoxic effects of commercial grade cypermethrin on fish peripheral erythrocytes	8
Exogenous exposure to dihydroxyacetone mimics high fructose induced oxidative stress and mitochondrial dysfunction	8
Oxidative stress, DNA damage, inflammation and gene expression in occupationally exposed university hospital anesthesia providers	8
Ameliorative potential of vitamin C and E against Roundup‐glyphosate induced genotoxicity triggering apoptosis in caprine granulosa cells	8
Long noncoding RNA polymorphisms and colorectal cancer risk: Progression and future perspectives	8
Bladder cancer tissue‐derived exosomes suppress ferroptosis of T24 bladder cancer cells by transporting miR‐217	8
Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma L5178Y cells and Caenorhabditis elegans worms by PacBio sequencing	7

A comparison of classical and 21st century genotoxicity tools: A proof of concept study of 18 chemicals comparing in vitro micronucleus, ToxTracker and genomics‐based methods (TGx‐DDI<	7
A scoping review of recent advances in the application of comet assay to Allium cepa roots	7
Toxicity and mutagenicity studies of 6PPD‐quinone in a marine invertebrate species and bacteria	6
Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate‐based formulations for genotoxic activity using in vitro assays	6
Implications of an epidemiological study showing an association between in utero NDMA exposure and childhood cancer	6
LncRNA polymorphisms and urologic cancer risk	6
In vitro genotoxicity potential investigation of 7 oxy‐PAHs	6
The use of benchmark dose uncertainty measurements for robust comparative potency analyses	5
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT)	5
Ulexite modulates the neurotoxicological outcomes of acetylferrocene‐exposed rainbow trout	5
Effect of dose and dose rate of gamma irradiation on the formation of micronuclei in bone marrow cells isolated from whole‐body‐irradiated mice	5
Transgenerational effects in offspring of chronically irradiated populations of Drosophila melanogaster after the Chernobyl accident	5
Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogeni	5
Lack of hydroxyurea‐associated mutagenesis in pediatric sickle cell disease patients	4
Polymorphism in cytochrome P4502A6 reduces the risk to head and neck cancer and modifies the treatment outcome	4
Effects of the air pollution dynamics on semen quality and sperm DNA methylation in men living in urban industrial agglomeration	4
Proteomic analysis of serum in workers exposed to diesel engine exhaust	4
Quantitative interpretation of ToxTracker dose–response data for potency comparisons and mode‐of‐action determination	4
The impact of environmental contaminants on extracellular vesicles and their key molecular regulators: A literature and database‐driven review	4
Biomonitoring of workers employed in a titanium dioxide production plant: Use of buccal micronucleus cytome assay as noninvasive biomarker to evaluate genotoxic and cytotoxic effects	4
Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case–control study	4
A new imaging platform (iScreen) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells	4
Polycyclic aromatic hydrocarbons induce endothelial injury through miR‐155 to promote atherosclerosis	4
Mutational signatures in T‐lymphocytes of rats treated with N‐propyl‐N‐nitrosourea and procarbazine	3
In vitro relationships of galactic cosmic radiation and epigenetic clocks in human bronchial epithelial cells	3
TIM‐3 polymorphism is involved in the progression of esophageal squamous cell carcinoma by regulating gene expression	3
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology	3
Mutagenicity of a novel 2‐phenylbenzotriazole (non‐chlorinated 2‐phenylbenzotriazole‐9) in mice	3
Impact of individual factors on DNA methylation of drug metabolism genes: A systematic review	3
The aflatoxin B₁‐induced imidazole ring‐opened guanine adduct: High mutagenic potential that is minimally affected by sequence context	3
In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT)	3
Chromosome damage in regions with different levels of air pollution	3
Identification of a dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in lung squamous cell carcinoma	3
Evaluation ofPIG‐A‐mutated granulocytes and ex‐vivo binucleated micronucleated lymphocytes frequencies after breast cancer radiotherapy in humans	3
Analysis of mutations in tumor and normal adjacent tissue via fluorescence detection	3
Determination of a positive response in the Ames Salmonella mutagenicity assay	3
In vitro human cell‐based aneugen molecular mechanism assay	2
Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by HiFi sequencing	2
Genotoxicity evaluation of orally administered styrene monomer in mice using comet, micronucleus, and Pig‐a endpoints	2
Investigation of the potential mutagenicity of ethyl tertiary‐butyl ether in the tumor target tissue using transgenic Big Blue Fischer 344 rats following whole body inhalation exposure	2
Utility of ToxTracker in animal alternative testing strategy for fragrance materials	2
Circ_0000033 up‐regulates NUAK2 by sequestering miR‐378a‐3p to promote breast tumorigenesis	2
Cadmium exposure induces necroptosis of porcine spleen via ROS‐mediated activation of STAT1/RIPK3 signaling pathway	2
Identification of differential methylome signatures of white pigmented skin patches in Nili Ravi buffalo of India	2
Radiobiological features in offspring of natural populations of Drosophila melanogaster after Chernobyl accident	2
Inability of GSTT1 to activate iodinated halomethanes to mutagens in Salmonella	2
Bisphenols induce human genomic damage and modulate HERVs/env expression	2
Micronucleated erythrocytes in peripheral blood from neonate rats fed by nursing mothers exposed to X‐rays	2
Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting	2
Templated insertions—DNA repair gets acrobatic	2

Improving knowledge on genotoxicity dynamics in somatic and germ cells of crayfish (Procambarus clarkii)	2
The role of Transcription Factor IIH complex in nucleotide excision repair	2
Global and gene‐specific promoter methylation, and micronuclei induction in lead‐exposed workers: A cross‐sectional study	2
The aryl hydrocarbon receptor (AhR) activation mediates benzo(a)pyrene‐induced overexpression of AQP3 and Notch1 in HaCaT cells	2
DNA damage and oxidative stress in gill cells of Cnesterodon decemmaculatus exposed to pesticides by runoff source in an agricultural basin	2
AOP report: Development of an adverse outcome pathway for deposition of energy leading to learning and memory impairment	2
A study on Amygdalin's genotoxicological safety and modulatory activity in human peripheral lymphocytes in vitro	2
Increased DNA strand breaks and neoplastic transformation in human bladder cells treated with pioglitazone	2
Design of a digital‐PCR assay to quantify fragmented human mitochondrial DNA	2
Concentration‐ and time‐dependent induction of Cyp1a and DNA damage response by benzo(a)pyrene in LMH three‐dimensional spheroids	2
Decrease of air pollution during lockdown in Tuscany (Italy): An effect on sperm DNA fragmentation?	2
Genome‐wide impact of cytosine methylation and DNA sequence context on UV‐induced CPD formation	2