Environmental and Molecular Mutagenesis

Article	Citations
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: the special case of molnupiravir	44
Permitted daily exposure limits for noteworthy N‐nitrosamines	42
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing	24
Heavy metals modulate DNA compaction and methylation at CpG sites in the metal hyperaccumulator Arabidopsis halleri	19
Quercetin mediated attenuation of cadmium‐induced oxidative toxicity and apoptosis of spermatogenic cells in caprine testes in vitro	19
AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations	18
In vitro cytotoxicity and genotoxicity of single and combined pesticides used by Bolivian farmers	18
A comprehensive literature review and meta‐analysis of the prevalence of pan‐cancer BRCA mutations, homologous recombination repair gene mutations, and homologous recombination defic	17
Evaluation of the mutagenic effects of Molnupiravir and N4‐hydroxycytidine in bacterial and mammalian cells by HiFi sequencing	17
The role of epigenetics in the reproductive toxicity of environmental endocrine disruptors	16
Differences in cell death in methionine versus cysteine depletion	14
Mutagenicity and carcinogenicity of combustion emissions are impacted more by combustor technology than by fuel composition: A brief review	10
In vitro genotoxicity of dibutyl phthalate on A549 lung cells at air–liquid interface in exposure concentrations relevant at workplaces	10
Recommendations for conducting the rodent erythrocyte Pig‐a assay: A report from the HESI GTTCPig‐a Workgroup	10
Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose	10
Elevated urinary mutagenicity among those exposed to bituminous coal combustion emissions or diesel engine exhaust	10
PacBio sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens	9
Dietary fat intake during early pregnancy is associated with cord blood DNA methylation at IGF2 and H19 genes in newborns	9
Ameliorative potential of vitamin C and E against Roundup‐glyphosate induced genotoxicity triggering apoptosis in caprine granulosa cells	8
Long noncoding RNA polymorphisms and colorectal cancer risk: Progression and future perspectives	8
Bladder cancer tissue‐derived exosomes suppress ferroptosis of T24 bladder cancer cells by transporting miR‐217	8
In vivo genotoxic effects of commercial grade cypermethrin on fish peripheral erythrocytes	8
Exogenous exposure to dihydroxyacetone mimics high fructose induced oxidative stress and mitochondrial dysfunction	8
Oxidative stress, DNA damage, inflammation and gene expression in occupationally exposed university hospital anesthesia providers	8
A scoping review of recent advances in the application of comet assay to Allium cepa roots	7

Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma L5178Y cells and Caenorhabditis elegans worms by PacBio sequencing	7
A comparison of classical and 21st century genotoxicity tools: A proof of concept study of 18 chemicals comparing in vitro micronucleus, ToxTracker and genomics‐based methods (TGx‐DDI<	7
In vitro genotoxicity potential investigation of 7 oxy‐PAHs	6
Toxicity and mutagenicity studies of 6PPD‐quinone in a marine invertebrate species and bacteria	6
Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate‐based formulations for genotoxic activity using in vitro assays	6
Implications of an epidemiological study showing an association between in utero NDMA exposure and childhood cancer	6
LncRNA polymorphisms and urologic cancer risk	6
Effect of dose and dose rate of gamma irradiation on the formation of micronuclei in bone marrow cells isolated from whole‐body‐irradiated mice	5
Transgenerational effects in offspring of chronically irradiated populations of Drosophila melanogaster after the Chernobyl accident	5
Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogeni	5
The use of benchmark dose uncertainty measurements for robust comparative potency analyses	5
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT)	5
Ulexite modulates the neurotoxicological outcomes of acetylferrocene‐exposed rainbow trout	5
Proteomic analysis of serum in workers exposed to diesel engine exhaust	4
Quantitative interpretation of ToxTracker dose–response data for potency comparisons and mode‐of‐action determination	4
The impact of environmental contaminants on extracellular vesicles and their key molecular regulators: A literature and database‐driven review	4
Biomonitoring of workers employed in a titanium dioxide production plant: Use of buccal micronucleus cytome assay as noninvasive biomarker to evaluate genotoxic and cytotoxic effects	4
Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case–control study	4
A new imaging platform (iScreen) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells	4
Polycyclic aromatic hydrocarbons induce endothelial injury through miR‐155 to promote atherosclerosis	4
Lack of hydroxyurea‐associated mutagenesis in pediatric sickle cell disease patients	4
Polymorphism in cytochrome P4502A6 reduces the risk to head and neck cancer and modifies the treatment outcome	4
Effects of the air pollution dynamics on semen quality and sperm DNA methylation in men living in urban industrial agglomeration	4
Chromosome damage in regions with different levels of air pollution	3
Identification of a dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in lung squamous cell carcinoma	3
Evaluation ofPIG‐A‐mutated granulocytes and ex‐vivo binucleated micronucleated lymphocytes frequencies after breast cancer radiotherapy in humans	3
Analysis of mutations in tumor and normal adjacent tissue via fluorescence detection	3
Determination of a positive response in the Ames Salmonella mutagenicity assay	3
Mutational signatures in T‐lymphocytes of rats treated with N‐propyl‐N‐nitrosourea and procarbazine	3
In vitro relationships of galactic cosmic radiation and epigenetic clocks in human bronchial epithelial cells	3
TIM‐3 polymorphism is involved in the progression of esophageal squamous cell carcinoma by regulating gene expression	3
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology	3
Mutagenicity of a novel 2‐phenylbenzotriazole (non‐chlorinated 2‐phenylbenzotriazole‐9) in mice	3
Impact of individual factors on DNA methylation of drug metabolism genes: A systematic review	3
The aflatoxin B1‐induced imidazole ring‐opened guanine adduct: High mutagenic potential that is minimally affected by sequence context	3
In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT)	3
Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting	2
Templated insertions—DNA repair gets acrobatic	2
Improving knowledge on genotoxicity dynamics in somatic and germ cells of crayfish (Procambarus clarkii)	2
The role of Transcription Factor IIH complex in nucleotide excision repair	2
Global and gene‐specific promoter methylation, and micronuclei induction in lead‐exposed workers: A cross‐sectional study	2
The aryl hydrocarbon receptor (AhR) activation mediates benzo(a)pyrene‐induced overexpression of AQP3 and Notch1 in HaCaT cells	2
DNA damage and oxidative stress in gill cells of Cnesterodon decemmaculatus exposed to pesticides by runoff source in an agricultural basin	2
AOP report: Development of an adverse outcome pathway for deposition of energy leading to learning and memory impairment	2
A study on Amygdalin's genotoxicological safety and modulatory activity in human peripheral lymphocytes in vitro	2
Increased DNA strand breaks and neoplastic transformation in human bladder cells treated with pioglitazone	2
Design of a digital‐PCR assay to quantify fragmented human mitochondrial DNA	2
Concentration‐ and time‐dependent induction of Cyp1a and DNA damage response by benzo(a)pyrene in LMH three‐dimensional spheroids	2
Decrease of air pollution during lockdown in Tuscany (Italy): An effect on sperm DNA fragmentation?	2
Genome‐wide impact of cytosine methylation and DNA sequence context on UV‐induced CPD formation	2

In vitro human cell‐based aneugen molecular mechanism assay	2
Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by HiFi sequencing	2
Genotoxicity evaluation of orally administered styrene monomer in mice using comet, micronucleus, and Pig‐a endpoints	2
Investigation of the potential mutagenicity of ethyl tertiary‐butyl ether in the tumor target tissue using transgenic Big Blue Fischer 344 rats following whole body inhalation exposure	2
Utility of ToxTracker in animal alternative testing strategy for fragrance materials	2
Circ_0000033 up‐regulates NUAK2 by sequestering miR‐378a‐3p to promote breast tumorigenesis	2
Cadmium exposure induces necroptosis of porcine spleen via ROS‐mediated activation of STAT1/RIPK3 signaling pathway	2
Identification of differential methylome signatures of white pigmented skin patches in Nili Ravi buffalo of India	2
Radiobiological features in offspring of natural populations of Drosophila melanogaster after Chernobyl accident	2
Inability of GSTT1 to activate iodinated halomethanes to mutagens in Salmonella	2
Bisphenols induce human genomic damage and modulate HERVs/env expression	2
Micronucleated erythrocytes in peripheral blood from neonate rats fed by nursing mothers exposed to X‐rays	2
Utility of a next‐generation framework for assessment of genomic damage: A case study using the pharmaceutical drug candidate etoposide	1
Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity	1
Genotoxicity assessment in HepaRG™ cells as a new approach methodology follow up to a positive response in the human TK6 cell micronucleus assay: Naphthalene case study	1
Exploring the molecular and functional cellular response to hydrazine via transcriptomics and DNA repair mutant cell lines	1
Modulation of gene expression and inflammation but not DNA damage after sevoflurane anesthesia	1
The in vitro genotoxicity potency of mixtures of pyrrolizidine alkaloids can be explained by dose addition of the individual mixture components	1
CircRNA RNF10 inhibits tumorigenicity by targeting miR‐942‐5p/GOLIM4 axis in breast cancer	1
Mutagenicity of the organic fraction of World Trade Center dust	1
Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo m	1
Effect of smoking on methylation and semen parameters	1
Cytogenotoxicity effects in addicts with multidrug consumption	1
ASIP gene polymorphism associated with black coat and skin color in Murrah buffalo	1
Mutagenicity of the Danube River: The contribution of liquid phase and particulate suspended matter	1
Functional roles and cancer variants of the bifunctional glycosylase NEIL2	1
Oxidative DNA damage on the VEGF G‐quadruplex forming promoter is repaired via long‐patch BER	1
Assessing the genotoxicity of N‐nitrosodiethylamine with three in vivo endpoints in male Big Blue® transgenic and wild‐type C57BL/6N mice	1
AOP report: Development of an adverse outcome pathway for deposition of energy leading to cataracts	1
Microsatellite mutation frequencies in river otters (Lontra Canadensis) from the Athabasca Oil Sands region are correlated to polycyclic aromatic compound tissue burden	1
DNAdamage in a Chilean population exposed to pesticides and its association withPON1(Q192RandL55M) susceptibility biomarker	1
The PIG‐A gene mutation assay in human biomonitoring and disease	1
Downregulation of circular RNA hsa_circ_0087856 sensitizes bladder cancer cells to cisplatin through targeting miR‐1184/CITED2 signaling	1
Occupational exposure to diesel engine exhaust and serum levels of microRNAs in a cross‐sectional molecular epidemiology study in China	1
A promising Ames battery for mutagenicity characterization of new dyes	1
The association between serum estradiol levels and sperm DNA integrity	1
Assessing testicular germ cell DNA damage in the comet assay; introduction of a proof‐of‐concept	1
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High frequency of silent mutations in gyrA gene of Mycobacterium tuberculosis in Indian isolates	0
Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI	0
Mutational spectra induced by flavonoid extracts from pepper tree (Schinus terebinthifolius, Raddi) stem bark	0
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Genotoxic repercussion of high‐intensity radiation (x‐rays) on hospital radiographers	0
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Power analyses to inform Duplex Sequencing study designs for MutaMouse liver and bone marrow	0
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Mutagenicity of the agriculture pesticide chlorothalonil assessed by somatic mutation and recombination test in Drosophila melanogaster	0
Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology	0
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Within‐laboratory reproducibility of Ames test results: Are repeat tests necessary?	0
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Abstracts From the 54th Annual Meeting of the Environmental Mutagenesis and Genomics Society, September 9 – 13, 2023 ‐ Chicago, IL, USA, EMGS in the Windy City: Billowing the Sails of DNA Science	0
Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment	0
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Morphological markers of chromosomal instability in bone marrow aspiration and trephine biopsy of acute leukemia and myelodysplastic syndrome	0
Investigations on the genotoxic potential of styrene in Fischer 344 rats using multiple endpoints	0
Visualization strategies to aid interpretation of high‐dimensional genotoxicity data	0
Introducing AOP Reports: Collaborative review and publication of adverse outcome pathways	0
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Establishment of a nonradioactive DNA ligation assay and its applications in murine tissues	0
Genotoxicity evaluation of gene therapies: A report from the International Workshop on Genotoxicity Testing (IWGT) 2022	0
The association of epidermal growth factor variant with oral squamous cell carcinoma	0
Abstracts From the 55th Annual Meeting of the Environmental Mutagenesis and Genomics Society, September 7 – 11, 2024 ‐ Palm Springs, CA, USA, An Oasis of DNA Discoveries	0
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The antiretroviral agents azidothymidine, stavudine, and didanosine have the identical mutational fingerprint in the rpoB region of Escherichia coli	0

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Mutation spectra of the BRCA1/2 genes in human breast and ovarian cancer and germline	0
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Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review	0
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Evaluation of the nitrosamine impurities of ACE inhibitors using computational, in vitro, and in vivo methods demonstrate no genotoxic potential	0
Interaction of cytochrome P450s with environmental risk factors increases their expression and risk to head and neck cancer	0
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Comparative analysis of micronucleus induction and DNA damage biomarkers in TK6 and A375 cells using flow cytometry	0
Clonality, trafficking, and molecular alterations among Hprt mutant T lymphocytes isolated from control mice versus mice treated with N‐ethyl‐N‐nitrosourea	0
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Remembering Radim J. Šrám	0
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Mouse models to explore the biological and organismic role of DNA polymerase beta	0
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AOP report: Development of an adverse outcome pathway for deposition of energy leading to abnormal vascular remodeling	0
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Firefighting, per‐ and polyfluoroalkyl substances, and DNA methylation of genes associated with prostate cancer risk	0
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Genotoxicity in humans exposed to arsenic, lithium, and boron in drinking water in the Bolivian Andes—A cross sectional study	0
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Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (I	0
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Anatomy of a hotspot: Cisplatin hotspots in the tdk gene of Escherichia coli	0
Comparison between inhalational anesthetics in terms of DNA damage and immunological markers	0
The regulatory function of tandem repeat VNTR2‐1 in hTERT gene involves basic Helix–loop–helix family transcription factors	0
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Poly‐ADP‐ribosylation dynamics, signaling, and analysis	0
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AOP Report: Development of an adverse outcome pathway for deposition of energy leading to bone loss	0
In vitro and in vivo assessments of the genotoxic potential of 3‐chloroallyl alcohol	0
Correction to “Mutation spectra of the BRCA1/2 genes in human breast and ovarian cancer and germline”	0
Assessment of genotoxic potential of fragrance materials in the chicken egg assays	0
A cross‐sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements	0
Targeted proteomic scan identifies alteration of serum proteins among workers occupationally exposed to low levels of trichloroethylene	0
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Abstracts from the 13th International Conference on Environmental Mutagens and 53rd Annual Meeting of the Environmental Mutagenesis and Genomics Society, August 27 ‐ September 1, 2022 ‐ Ottawa, Canada	0
Erratum to “Genotoxic repercussion of high‐intensity radiation (x‐rays) on hospital radiographers”	0
Mutagenicity of N‐hydroxy‐4‐aminobiphenyl in human TP53 knock‐in (Hupki) mouse embryo fibroblasts	0
Abstracts from the Environmental Mutagenesis and Genomics Society 52nd Annual Meeting, September 22–25, 2021, Virtual Meeting ‐ Real Science Program Chair: Jeff Bemis, PhD New Investigator Co‐Chair: I	0
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson	0
Transcriptome profiling of guinea pig skin exposed to a high‐power terahertz source	0
Investigating aneuploidy‐inducing effect of Nemacur, Rogor, and Dursban in human peripheral blood lymphocyte cultures	0
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Kinetics of the in vivo genotoxic and radioprotective effects of methyl gallate and epigallocatechin gallate	0
Artificial targeting of the NEIL1 DNA glycosylase to the mitochondria	0
Associations between KCNQ1OT1 genetic variation rs10766212 and susceptibility to colorectal cancer and clinical stage in a Chinese Han population	0
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Qualitative and quantitative changes in mitochondrial DNA associated with cervical cancer: A comprehensive review	0
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Veterinarians exposed to inhaled anesthetic present chromosome damage, apoptosis and cell cycle changes	0
Urinary mutagenicity and bladder cancer risk in northern New England	0
Pig‐a gene mutations in bone marrow granulocytes of procarbazine‐treated F344 rats	0
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Assessment of the genotoxicity of tert‐butyl alcohol in an in vivo thyroid comet assay	0
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Mutagenicity evaluation of methyl tertiary‐ butyl ether in multiple tissues of transgenic rats following whole body inhalation exposure	0
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Absence of genotoxicity following pulmonary exposure to metal oxides of copper, tin, aluminum, zinc, and titanium in mice	0
Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures	0
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