Environmental and Molecular Mutagenesis

Article	Citations
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: the special case of molnupiravir	39
A review on the 40th anniversary of the first regulation of drinking water disinfection by‐products	39
Permitted daily exposure limits for noteworthy N‐nitrosamines	29
Solar ultraviolet‐induced DNA damage response: Melanocytes story in transformation to environmental melanomagenesis	22
ATR signaling in mammalian meiosis: From upstream scaffolds to downstream signaling	21
Roles of Chk2/CHEK2 in guarding against environmentally induced DNA damage and replication‐stress	21
DNA–protein crosslinks from environmental exposure: Mechanisms of formation and repair	20
Subacute cannabidiol alters genome‐wide DNA methylation in adult mouse hippocampus	19
Quercetin mediated attenuation of cadmium‐induced oxidative toxicity and apoptosis of spermatogenic cells in caprine testes in vitro	18
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing	18
Inhibition of urinary bladder cancer cell proliferation by silibinin	17
PIG‐A gene mutation as a genotoxicity biomarker in human population studies: An investigation in lead‐exposed workers	16
In vitro cytotoxicity and genotoxicity of single and combined pesticides used by Bolivian farmers	16
The role of epigenetics in the reproductive toxicity of environmental endocrine disruptors	15
Heavy metals modulate DNA compaction and methylation at CpG sites in the metal hyperaccumulator Arabidopsis halleri	14
Differences in cell death in methionine versus cysteine depletion	13
Human blood PIG‐A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra‐ and inter‐subject variation	13
Long INterspersed element‐1 mobility as a sensor of environmental stresses	13
Genotoxicity as a toxicologically relevant endpoint to inform risk assessment: A case study with ethylene oxide	11
Evaluation of the mutagenic effects of Molnupiravir and N4‐hydroxycytidine in bacterial and mammalian cells by HiFi sequencing	11
Radio‐adaptive response, individual radio‐sensitivity and correlation of base excision repair gene polymorphism (hOGG1, APE1, XRCC1, and LIGASE1) in human peripheral blood	11
AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations	11
Clothianidin induces DNA damage and oxidative stress in bronchial epithelial cells	10
Thirdhand smoke exposure causes replication stress and impaired transcription in human lung cells	9
Recommendations for conducting the rodent erythrocyte Pig‐a assay: A report from the HESI GTTCPig‐a Workgroup	9

In vitro genotoxicity of dibutyl phthalate on A549 lung cells at air–liquid interface in exposure concentrations relevant at workplaces	9
Modified hydrated sodium calcium aluminosilicate‐supplemented diet protects porcine oocyte quality from zearalenone toxicity	9
Heritable hazards of smoking: Applying the “clean sheet” framework to further science and policy	8
Dietary fat intake during early pregnancy is associated with cord blood DNA methylation at IGF2 and H19 genes in newborns	8
Elevated urinary mutagenicity among those exposed to bituminous coal combustion emissions or diesel engine exhaust	8
Long noncoding RNA polymorphisms and colorectal cancer risk: Progression and future perspectives	8
Oxidative stress, DNA damage, inflammation and gene expression in occupationally exposed university hospital anesthesia providers	8
In vivo genotoxic effects of commercial grade cypermethrin on fish peripheral erythrocytes	7
Similar polycyclic aromatic hydrocarbon and genotoxicity profiles of atmospheric particulate matter from cities on three different continents	7
Ameliorative potential of vitamin C and E against Roundup‐glyphosate induced genotoxicity triggering apoptosis in caprine granulosa cells	7
PacBio sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens	7
Genetic instability assessed by telomere length and micronucleus in physicians exposed to anesthetics	7
Mutagenicity and carcinogenicity of combustion emissions are impacted more by combustor technology than by fuel composition: A brief review	7
Promoter hypermethylation in CSF3R induces peripheral neutrophil reduction in benzene‐exposure poisoning	7
Exogenous exposure to dihydroxyacetone mimics high fructose induced oxidative stress and mitochondrial dysfunction	7
A comprehensive literature review and meta‐analysis of the prevalence of pan‐cancer BRCA mutations, homologous recombination repair gene mutations, and homologous recombination defic	6
Bladder cancer tissue‐derived exosomes suppress ferroptosis of T24 bladder cancer cells by transporting miR‐217	6
Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose	6
In vitro genotoxicity potential investigation of 7 oxy‐PAHs	6
Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment	6
LncRNA polymorphisms and urologic cancer risk	6
The release of contaminants from steel slags and natural aggregates: Evaluation of toxicity and genotoxicity	6
A comparison of classical and 21st century genotoxicity tools: A proof of concept study of 18 chemicals comparing in vitro micronucleus, ToxTracker and genomics‐based methods (TGx‐DDI<	6
Implications of an epidemiological study showing an association between in utero NDMA exposure and childhood cancer	5
Biomarkers of genome instability in normal mammalian genomes following drug‐induced replication stress	5
Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogeni	5
A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis	5
Assessment of systemic genetic damage in pediatric inflammatory bowel disease	5
Quantification of cancer driver mutations in human breast and lung DNA using targeted, error‐corrected CarcSeq	5
Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma L5178Y cells and Caenorhabditis elegans worms by PacBio sequencing	5
Transgenerational effects in offspring of chronically irradiated populations of Drosophila melanogaster after the Chernobyl accident	5
Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate‐based formulations for genotoxic activity using in vitro assays	4
CD59‐deficient bone marrow erythroid cells from rats treated with procarbazine and propyl‐nitrosourea have mutations in thePig‐agene	4
Proteomic analysis of serum in workers exposed to diesel engine exhaust	4
A scoping review of recent advances in the application of comet assay to Allium cepa roots	4
Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case–control study	4
Mitochondrial DNA copy number and cytogenetic damage among fuel filling station attendants	4
Biomonitoring of workers employed in a titanium dioxide production plant: Use of buccal micronucleus cytome assay as noninvasive biomarker to evaluate genotoxic and cytotoxic effects	3
In vitro and in vivo mammalian mutation assays support a nonmutagenic mechanism of carcinogenicity for hydrazine	3
The impact of environmental contaminants on extracellular vesicles and their key molecular regulators: A literature and database‐driven review	3
The use of benchmark dose uncertainty measurements for robust comparative potency analyses	3
Analysis of mutations in tumor and normal adjacent tissue via fluorescence detection	3
Alteration of methylation status in archival DNA samples: A qualitative assessment by methylation specific polymerase chain reaction	3
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT)	3
Effect of dose and dose rate of gamma irradiation on the formation of micronuclei in bone marrow cells isolated from whole‐body‐irradiated mice	3
Cytotoxicity and genotoxicity assays of halobenzoquinones disinfection byproducts using different human cell lines	3
Identification of a dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in lung squamous cell carcinoma	3
Evaluation ofPIG‐A‐mutated granulocytes and ex‐vivo binucleated micronucleated lymphocytes frequencies after breast cancer radiotherapy in humans	3
Polymorphism in cytochrome P4502A6 reduces the risk to head and neck cancer and modifies the treatment outcome	3
Polycyclic aromatic hydrocarbons induce endothelial injury through miR‐155 to promote atherosclerosis	3

An introduction for the special issue on environmental health and genome integrity	2
In vitro relationships of galactic cosmic radiation and epigenetic clocks in human bronchial epithelial cells	2
TIM‐3 polymorphism is involved in the progression of esophageal squamous cell carcinoma by regulating gene expression	2
Quantitative interpretation of ToxTracker dose–response data for potency comparisons and mode‐of‐action determination	2
DNA damage and oxidative stress in gill cells of Cnesterodon decemmaculatus exposed to pesticides by runoff source in an agricultural basin	2
Inability of GSTT1 to activate iodinated halomethanes to mutagens in Salmonella	2
FAM35A/SHLD2/RINN2: A novel determinant of double strand break repair pathway choice and genome stability in cancer	2
Micronucleated erythrocytes in peripheral blood from neonate rats fed by nursing mothers exposed to X‐rays	2
Concentration‐ and time‐dependent induction of Cyp1a and DNA damage response by benzo(a)pyrene in LMH three‐dimensional spheroids	2
Mutational signatures in T‐lymphocytes of rats treated with N‐propyl‐N‐nitrosourea and procarbazine	2
Global and gene‐specific promoter methylation, and micronuclei induction in lead‐exposed workers: A cross‐sectional study	2
A new imaging platform (iScreen) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells	2
Ulexite modulates the neurotoxicological outcomes of acetylferrocene‐exposed rainbow trout	2
Determination of a positive response in the Ames Salmonella mutagenicity assay	2
Design of a digital‐PCR assay to quantify fragmented human mitochondrial DNA	2
Increased DNA strand breaks and neoplastic transformation in human bladder cells treated with pioglitazone	2
Enhancing the sensitivity of the thymidine kinase assay by using DNA repair‐deficient human TK6 cells	2
Lack of hydroxyurea‐associated mutagenesis in pediatric sickle cell disease patients	2
Effects of the air pollution dynamics on semen quality and sperm DNA methylation in men living in urban industrial agglomeration	2
Radiobiological features in offspring of natural populations of Drosophila melanogaster after Chernobyl accident	2
In vitro human cell‐based aneugen molecular mechanism assay	1
Image analysis of mechanistic protein biomarkers for the characterization of genotoxicants: Aneugens, clastogens, and reactive oxygen species inducers	1
Chromosome damage in regions with different levels of air pollution	1
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology	1
Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting	1
Toxicity and mutagenicity studies of 6PPD‐quinone in a marine invertebrate species and bacteria	1
The aflatoxin B1‐induced imidazole ring‐opened guanine adduct: High mutagenic potential that is minimally affected by sequence context	1
DNAdamage in a Chilean population exposed to pesticides and its association withPON1(Q192RandL55M) susceptibility biomarker	1
Downregulation of circular RNA hsa_circ_0087856 sensitizes bladder cancer cells to cisplatin through targeting miR‐1184/CITED2 signaling	1
Occupational exposure to diesel engine exhaust and serum levels of microRNAs in a cross‐sectional molecular epidemiology study in China	1
Mutagenicity of the organic fraction of World Trade Center dust	1
Testing of acetaminophen in support of the international multilaboratory in vivo rat Pig‐a assay validation trial	1
CircRNA RNF10 inhibits tumorigenicity by targeting miR‐942‐5p/GOLIM4 axis in breast cancer	1
Utility of ToxTracker in animal alternative testing strategy for fragrance materials	1
Utility of a next‐generation framework for assessment of genomic damage: A case study using the pharmaceutical drug candidate etoposide	1
In vivo kinetics of the genotoxic and cytotoxic activities of cladribine and clofarabine	1
Identification of differential methylome signatures of white pigmented skin patches in Nili Ravi buffalo of India	1
A promising Ames battery for mutagenicity characterization of new dyes	1
Bisphenols induce human genomic damage and modulate HERVs/env expression	1
Mutagenicity of a novel 2‐phenylbenzotriazole (non‐chlorinated 2‐phenylbenzotriazole‐9) in mice	1
A study on Amygdalin's genotoxicological safety and modulatory activity in human peripheral lymphocytes in vitro	1
Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo m	1
Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity	1
Intra‐ and inter‐laboratory reproducibility of the rat blood Pig‐a gene mutation assay	1
Interaction of cytochrome P450s with environmental risk factors increases their expression and risk to head and neck cancer	0
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Targeted proteomic scan identifies alteration of serum proteins among workers occupationally exposed to low levels of trichloroethylene	0
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Impact of individual factors on DNA methylation of drug metabolism genes: A systematic review	0
Abstracts from the 13th International Conference on Environmental Mutagens and 53rd Annual Meeting of the Environmental Mutagenesis and Genomics Society, August 27 ‐ September 1, 2022 ‐ Ottawa, Canada	0
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In vitro and in vivo assessments of the genotoxic potential of 3‐chloroallyl alcohol	0
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Investigating aneuploidy‐inducing effect of Nemacur, Rogor, and Dursban in human peripheral blood lymphocyte cultures	0
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ASIP gene polymorphism associated with black coat and skin color in Murrah buffalo	0
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Genotoxic repercussion of high‐intensity radiation (x‐rays) on hospital radiographers	0
Genotoxicity in humans exposed to arsenic, lithium, and boron in drinking water in the Bolivian Andes—A cross sectional study	0
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Exploring the molecular and functional cellular response to hydrazine via transcriptomics and DNA repair mutant cell lines	0
The association between serum estradiol levels and sperm DNA integrity	0
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Cytogenotoxicity effects in addicts with multidrug consumption	0
Modulation of gene expression and inflammation but not DNA damage after sevoflurane anesthesia	0
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The in vitro genotoxicity potency of mixtures of pyrrolizidine alkaloids can be explained by dose addition of the individual mixture components	0
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Mutagenicity of the Danube River: The contribution of liquid phase and particulate suspended matter	0
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Investigation of the potential mutagenicity of ethyl tertiary‐butyl ether in the tumor target tissue using transgenic Big Blue Fischer 344 rats following whole body inhalation exposure	0
Abstracts from the Environmental Mutagenesis and Genomics Society 51st Annual Meeting, September 12–16, 2020	0
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The regulatory function of tandem repeat VNTR2‐1 in hTERT gene involves basic Helix–loop–helix family transcription factors	0
Effect of smoking on methylation and semen parameters	0

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The association of epidermal growth factor variant with oral squamous cell carcinoma	0
Genotoxicity assessment in HepaRG™ cells as a new approach methodology follow up to a positive response in the human TK6 cell micronucleus assay: Naphthalene case study	0
Pig‐a gene mutations in bone marrow granulocytes of procarbazine‐treated F344 rats	0
A cross‐sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements	0
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Microsatellite mutation frequencies in river otters (Lontra Canadensis) from the Athabasca Oil Sands region are correlated to polycyclic aromatic compound tissue burden	0
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Decrease of air pollution during lockdown in Tuscany (Italy): An effect on sperm DNA fragmentation?	0
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Associations between KCNQ1OT1 genetic variation rs10766212 and susceptibility to colorectal cancer and clinical stage in a Chinese Han population	0
Abstracts from the Environmental Mutagenesis and Genomics Society 52nd Annual Meeting, September 22–25, 2021, Virtual Meeting ‐ Real Science Program Chair: Jeff Bemis, PhD New Investigator Co‐Chair: I	0
Remembering Radim J. Šrám	0
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Kinetics of the in vivo genotoxic and radioprotective effects of methyl gallate and epigallocatechin gallate	0
Veterinarians exposed to inhaled anesthetic present chromosome damage, apoptosis and cell cycle changes	0
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Genotoxicity evaluation of orally administered styrene monomer in mice using comet, micronucleus, and Pig‐a endpoints	0
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Introducing AOP Reports: Collaborative review and publication of adverse outcome pathways	0
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Improving knowledge on genotoxicity dynamics in somatic and germ cells of crayfish (Procambarus clarkii)	0
Genome‐wide impact of cytosine methylation and DNA sequence context on UV‐induced CPD formation	0
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The aryl hydrocarbon receptor (AhR) activation mediates benzo(a)pyrene‐induced overexpression of AQP3 and Notch1 in HaCaT cells	0
Clonality, trafficking, and molecular alterations among Hprt mutant T lymphocytes isolated from control mice versus mice treated with N‐ethyl‐N‐nitrosourea	0
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The PIG‐A gene mutation assay in human biomonitoring and disease	0
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Cadmium exposure induces necroptosis of porcine spleen via ROS‐mediated activation of STAT1/RIPK3 signaling pathway	0
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Mutational spectra induced by flavonoid extracts from pepper tree (Schinus terebinthifolius, Raddi) stem bark	0
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Circ_0000033 up‐regulates NUAK2 by sequestering miR‐378a‐3p to promote breast tumorigenesis	0
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Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review	0
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Assessing testicular germ cell DNA damage in the comet assay; introduction of a proof‐of‐concept	0
Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI	0
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Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by HiFi sequencing	0
Abstracts From the 54th Annual Meeting of the Environmental Mutagenesis and Genomics Society, September 9 – 13, 2023 ‐ Chicago, IL, USA, EMGS in the Windy City: Billowing the Sails of DNA Science	0
Morphological markers of chromosomal instability in bone marrow aspiration and trephine biopsy of acute leukemia and myelodysplastic syndrome	0
Erratum to “Genotoxic repercussion of high‐intensity radiation (x‐rays) on hospital radiographers”	0
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Transcriptome profiling of guinea pig skin exposed to a high‐power terahertz source	0
Functional roles and cancer variants of the bifunctional glycosylase NEIL2	0
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Mutagenicity of N‐hydroxy‐4‐aminobiphenyl in human TP53 knock‐in (Hupki) mouse embryo fibroblasts	0
The role of Transcription Factor IIH complex in nucleotide excision repair	0
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Oxidative DNA damage on the VEGF G‐quadruplex forming promoter is repaired via long‐patch BER	0
The antiretroviral agents azidothymidine, stavudine, and didanosine have the identical mutational fingerprint in the rpoB region of Escherichia coli	0
Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures	0
In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT)	0
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Templated insertions—DNA repair gets acrobatic	0
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