Environmental and Molecular Mutagenesis

Article	Citations
Abstracts from the 13th International Conference on Environmental Mutagens and 53rd Annual Meeting of the Environmental Mutagenesis and Genomics Society, August 27 ‐ September 1, 2022 ‐ Ottawa, Canada	50
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Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by HiFi sequencing	27
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Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose	24
Comparison between inhalational anesthetics in terms of DNA damage and immunological markers	22
Functional roles and cancer variants of the bifunctional glycosylase NEIL2	22
Effects of the air pollution dynamics on semen quality and sperm DNA methylation in men living in urban industrial agglomeration	19
Exploring the molecular and functional cellular response to hydrazine via transcriptomics and DNA repair mutant cell lines	15
In vitro and in vivo assessments of the genotoxic potential of 3‐chloroallyl alcohol	11
Poly‐ADP‐ribosylation dynamics, signaling, and analysis	10
Polycyclic aromatic hydrocarbons induce endothelial injury through miR‐155 to promote atherosclerosis	10
The PIG‐A gene mutation assay in human biomonitoring and disease	10
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Introducing AOP Reports: Collaborative review and publication of adverse outcome pathways	9
Veterinarians exposed to inhaled anesthetic present chromosome damage, apoptosis and cell cycle changes	9
A scoping review of recent advances in the application of comet assay to Allium cepa roots	8
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The impact of environmental contaminants on extracellular vesicles and their key molecular regulators: A literature and database‐driven review	8
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Utility of a next‐generation framework for assessment of genomic damage: A case study using the pharmaceutical drug candidate etoposide	7
Microsatellite mutation frequencies in river otters (Lontra Canadensis) from the Athabasca Oil Sands region are correlated to polycyclic aromatic compound tissue burden	7
Quantitative interpretation of ToxTracker dose–response data for potency comparisons and mode‐of‐action determination	7

Genotoxicity evaluation of gene therapies: A report from the International Workshop on Genotoxicity Testing (IWGT) 2022	6
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Synthesizing Genotoxicity Results in the MultiFlow Assay With Point‐of‐Departure Analysis and ToxPi Visualization Techniques	6
Genotoxicity evaluation of orally administered styrene monomer in mice using comet, micronucleus, and Pig‐a endpoints	6
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Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case–control study	6
Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (I	6
Bruce Nathan Ames, 1928–2024: A meaningful scientific life	6
Long noncoding RNA polymorphisms and colorectal cancer risk: Progression and future perspectives	5
Mutagenicity and carcinogenicity of combustion emissions are impacted more by combustor technology than by fuel composition: A brief review	5
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In vitro cytotoxicity and genotoxicity of single and combined pesticides used by Bolivian farmers	4
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Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson	4
Genotoxic repercussion of high‐intensity radiation (x‐rays) on hospital radiographers	4
Urinary mutagenicity and bladder cancer risk in northern New England	4
Correction to “Mutation spectra of the BRCA1/2 genes in human breast and ovarian cancer and germline”	4
Bisphenols induce human genomic damage and modulate HERVs/env expression	4
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AOP report: Development of an adverse outcome pathway for deposition of energy leading to learning and memory impairment	4
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Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity	3
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Downregulation of circular RNA hsa_circ_0087856 sensitizes bladder cancer cells to cisplatin through targeting miR‐1184/CITED2 signaling	3
DNAdamage in a Chilean population exposed to pesticides and its association withPON1(Q192RandL55M) susceptibility biomarker	3
Mutagenicity of the Danube River: The contribution of liquid phase and particulate suspended matter	3
Power analyses to inform Duplex Sequencing study designs for MutaMouse liver and bone marrow	3
Anatomy of a hotspot: Cisplatin hotspots in the tdk gene of Escherichia coli	3
Decrease of air pollution during lockdown in Tuscany (Italy): An effect on sperm DNA fragmentation?	3
Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI	3
Radiobiological features in offspring of natural populations of Drosophila melanogaster after Chernobyl accident	3
Ulexite modulates the neurotoxicological outcomes of acetylferrocene‐exposed rainbow trout	3
Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotox	3
Evaluation of the nitrosamine impurities of ACE inhibitors using computational, in vitro, and in vivo methods demonstrate no genotoxic potential	3
Comparative analysis of micronucleus induction and DNA damage biomarkers in TK6 and A375 cells using flow cytometry	2
Identification of a dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in lung squamous cell carcinoma	2
The regulatory function of tandem repeat VNTR2‐1 in hTERT gene involves basic Helix–loop–helix family transcription factors	2
Concentration‐ and time‐dependent induction of Cyp1a and DNA damage response by benzo(a)pyrene in LMH three‐dimensional spheroids	2
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Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology	2
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Mouse models to explore the biological and organismic role of DNA polymerase beta	2
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The role of Transcription Factor IIH complex in nucleotide excision repair	2
In vitro relationships of galactic cosmic radiation and epigenetic clocks in human bronchial epithelial cells	2
A study on Amygdalin's genotoxicological safety and modulatory activity in human peripheral lymphocytes in vitro	2
Visualization strategies to aid interpretation of high‐dimensional genotoxicity data	2
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The antiretroviral agents azidothymidine, stavudine, and didanosine have the identical mutational fingerprint in the rpoB region of Escherichia coli	2
High frequency of silent mutations in gyrA gene of Mycobacterium tuberculosis in Indian isolates	2
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Lack of hydroxyurea‐associated mutagenesis in pediatric sickle cell disease patients	2
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Elevated urinary mutagenicity among those exposed to bituminous coal combustion emissions or diesel engine exhaust	1
Genotoxicity in humans exposed to arsenic, lithium, and boron in drinking water in the Bolivian Andes—A cross sectional study	1
In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT)	1
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Cadmium exposure induces necroptosis of porcine spleen via ROS‐mediated activation of STAT1/RIPK3 signaling pathway	1
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Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review	1
Effect of dose and dose rate of gamma irradiation on the formation of micronuclei in bone marrow cells isolated from whole‐body‐irradiated mice	1
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ASIP gene polymorphism associated with black coat and skin color in Murrah buffalo	1
Investigations on the genotoxic potential of styrene in Fischer 344 rats using multiple endpoints	1
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Polymorphism in cytochrome P4502A6 reduces the risk to head and neck cancer and modifies the treatment outcome	1
Bladder cancer tissue‐derived exosomes suppress ferroptosis of T24 bladder cancer cells by transporting miR‐217	1
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Abstracts From the 54th Annual Meeting of the Environmental Mutagenesis and Genomics Society, September 9 – 13, 2023 ‐ Chicago, IL, USA, EMGS in the Windy City: Billowing the Sails of DNA Science	1
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Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT)	0
The in vitro genotoxicity potency of mixtures of pyrrolizidine alkaloids can be explained by dose addition of the individual mixture components	0
Investigating aneuploidy‐inducing effect of Nemacur, Rogor, and Dursban in human peripheral blood lymphocyte cultures	0
Mutational signatures in T‐lymphocytes of rats treated with N‐propyl‐N‐nitrosourea and procarbazine	0
Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting	0
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Improving knowledge on genotoxicity dynamics in somatic and germ cells of crayfish (Procambarus clarkii)	0
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: the special case of molnupiravir	0
Mutation spectra of the BRCA1/2 genes in human breast and ovarian cancer and germline	0
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Utility of ToxTracker in animal alternative testing strategy for fragrance materials	0
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Mutagenicity of a novel 2‐phenylbenzotriazole (non‐chlorinated 2‐phenylbenzotriazole‐9) in mice	0
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Abstracts From the 55th Annual Meeting of the Environmental Mutagenesis and Genomics Society, September 7 – 11, 2024 ‐ Palm Springs, CA, USA, An Oasis of DNA Discoveries	0
Design of a digital‐PCR assay to quantify fragmented human mitochondrial DNA	0
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In vitro genotoxicity potential investigation of 7 oxy‐PAHs	0
Re‐Evaluating Acceptable Intake: A Comparative Study of N‐Nitrosomorpholine and N‐Nitroso Reboxetine Potency	0
Identification of differential methylome signatures of white pigmented skin patches in Nili Ravi buffalo of India	0
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Permitted daily exposure limits for noteworthy N‐nitrosamines	0
AOP Report: Development of an adverse outcome pathway for deposition of energy leading to bone loss	0
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines	0
Chromosome damage in regions with different levels of air pollution	0
Machine learning enhances genotoxicity assessment using MultiFlow® DNA damage assay	0
Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo m	0
Extracellular Vesicle (EV) Mechanisms of Toxicity for Per and Polyfluoroalkyl Substances: Comparing Transcriptomic Points of Departure Across Global Versus EV Regulatory Gene Set	0
Mutagenicity of the organic fraction of World Trade Center dust	0
Circ_0000033 up‐regulates NUAK2 by sequestering miR‐378a‐3p to promote breast tumorigenesis	0
Review and meta‐analysis of gene expression biomarkers predictive of chemical‐induced genotoxicity in vivo	0
Remembering Radim J. Šrám	0
Dietary fat intake during early pregnancy is associated with cord blood DNA methylation at IGF2 and H19 genes in newborns	0
Morphological markers of chromosomal instability in bone marrow aspiration and trephine biopsy of acute leukemia and myelodysplastic syndrome	0
PacBio sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens	0
In vitro human cell‐based aneugen molecular mechanism assay	0
LncRNA polymorphisms and urologic cancer risk	0
Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model	0
Assessment of genotoxic potential of fragrance materials in the chicken egg assays	0
Mitigation of Volatile Chemicals' Effect on Adjacent Microtiter Plate Wells	0
Qualitative and quantitative changes in mitochondrial DNA associated with cervical cancer: A comprehensive review	0
In vivo genotoxic effects of commercial grade cypermethrin on fish peripheral erythrocytes	0
Transcriptome profiling of guinea pig skin exposed to a high‐power terahertz source	0
Epigenetic Modifications Associated With Wildland–Urban Interface (WUI) Firefighting	0

The aryl hydrocarbon receptor (AhR) activation mediates benzo(a)pyrene‐induced overexpression of AQP3 and Notch1 in HaCaT cells	0
Mutagenicity evaluation of methyl tertiary‐ butyl ether in multiple tissues of transgenic rats following whole body inhalation exposure	0
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Outcome of IWGT workshop on transcriptomic biomarkers for genotoxicity: Key considerations for bioinformatics	0
Cytogenotoxicity effects in addicts with multidrug consumption	0
AOP report: Development of an adverse outcome pathway for deposition of energy leading to cataracts	0
Tong‐man Ong (June 9, 1935–January 5, 2025)	0
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Clonality, trafficking, and molecular alterations among Hprt mutant T lymphocytes isolated from control mice versus mice treated with N‐ethyl‐N‐nitrosourea	0
Templated insertions—DNA repair gets acrobatic	0
The association between serum estradiol levels and sperm DNA integrity	0
Determination of a positive response in the Ames Salmonella mutagenicity assay	0
Global and gene‐specific promoter methylation, and micronuclei induction in lead‐exposed workers: A cross‐sectional study	0
Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity	0
Proteomic analysis of serum in workers exposed to diesel engine exhaust	0
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Evaluation of the mutagenic effects of Molnupiravir and N4‐hydroxycytidine in bacterial and mammalian cells by HiFi sequencing	0
Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma L5178Y cells and Caenorhabditis elegans worms by PacBio sequencing	0
AOP report: Development of an adverse outcome pathway for deposition of energy leading to abnormal vascular remodeling	0
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Genetic instability of a single exposure to sevoflurane at different concentrations in monitored mice	0
Benchmark Response (BMR) Values for In Vivo Mutagenicity Endpoints	0
Associations between KCNQ1OT1 genetic variation rs10766212 and susceptibility to colorectal cancer and clinical stage in a Chinese Han population	0
Assessment of the genotoxicity of tert‐butyl alcohol in an in vivo thyroid comet assay	0
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Within‐laboratory reproducibility of Ames test results: Are repeat tests necessary?	0
Assessing the impact of different solvents in the bacterial reverse mutation test	0
Transcriptomic and epigenomic signatures distinguish high‐ and low‐risk endotypes for liver tumor development	0
Assessing testicular germ cell DNA damage in the comet assay; introduction of a proof‐of‐concept	0
Mutagenicity of the agriculture pesticide chlorothalonil assessed by somatic mutation and recombination test in Drosophila melanogaster	0
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Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogeni	0
Interaction of cytochrome P450s with environmental risk factors increases their expression and risk to head and neck cancer	0
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Abstracts from the Environmental Mutagenesis and Genomics Society 52nd Annual Meeting, September 22–25, 2021, Virtual Meeting ‐ Real Science Program Chair: Jeff Bemis, PhD New Investigator Co‐Chair: I	0
A comprehensive literature review and meta‐analysis of the prevalence of pan‐cancer BRCA mutations, homologous recombination repair gene mutations, and homologous recombination defic	0
Occupational exposure to diesel engine exhaust and serum levels of microRNAs in a cross‐sectional molecular epidemiology study in China	0
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An Enhanced Metabolization Protocol for In Vitro Genotoxicity Assessment of N‐Nitrosamines in Mammalian Cells	0
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Implications of an epidemiological study showing an association between in utero NDMA exposure and childhood cancer	0
Oxidative DNA damage on the VEGF G‐quadruplex forming promoter is repaired via long‐patch BER	0
Impact of individual factors on DNA methylation of drug metabolism genes: A systematic review	0
Toxicity and mutagenicity studies of 6PPD‐quinone in a marine invertebrate species and bacteria	0
CircRNA RNF10 inhibits tumorigenicity by targeting miR‐942‐5p/GOLIM4 axis in breast cancer	0
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology	0
In vitro genotoxicity of dibutyl phthalate on A549 lung cells at air–liquid interface in exposure concentrations relevant at workplaces	0
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Erratum to “Genotoxic repercussion of high‐intensity radiation (x‐rays) on hospital radiographers”	0
Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment	0
The association of epidermal growth factor variant with oral squamous cell carcinoma	0
A new imaging platform (iScreen) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells	0
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Hollaender award 2023: Adventures in applied genetic toxicology	0
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing	0
Absence of genotoxicity following pulmonary exposure to metal oxides of copper, tin, aluminum, zinc, and titanium in mice	0
Kinetics of the in vivo genotoxic and radioprotective effects of methyl gallate and epigallocatechin gallate	0
Targeted proteomic scan identifies alteration of serum proteins among workers occupationally exposed to low levels of trichloroethylene	0
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The aflatoxin B1‐induced imidazole ring‐opened guanine adduct: High mutagenic potential that is minimally affected by sequence context	0
A cross‐sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements	0
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Genotoxicity assessment in HepaRG™ cells as a new approach methodology follow up to a positive response in the human TK6 cell micronucleus assay: Naphthalene case study	0
Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures	0
Establishment of a nonradioactive DNA ligation assay and its applications in murine tissues	0
Effect of smoking on methylation and semen parameters	0
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Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate‐based formulations for genotoxic activity using in vitro assays	0
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Firefighting, per‐ and polyfluoroalkyl substances, and DNA methylation of genes associated with prostate cancer risk	0
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AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations	0
Assessing the genotoxicity of N‐nitrosodiethylamine with three in vivo endpoints in male Big Blue® transgenic and wild‐type C57BL/6N mice	0
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Quercetin mediated attenuation of cadmium‐induced oxidative toxicity and apoptosis of spermatogenic cells in caprine testes in vitro	0
DNA damage and oxidative stress in gill cells of Cnesterodon decemmaculatus exposed to pesticides by runoff source in an agricultural basin	0
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Genome‐wide impact of cytosine methylation and DNA sequence context on UV‐induced CPD formation	0
Artificial targeting of the NEIL1 DNA glycosylase to the mitochondria	0
Modulation of gene expression and inflammation but not DNA damage after sevoflurane anesthesia	0
Investigation of mutagenicity of styrene in tumor target and non‐target tissues of transgenic Big Blue® mice	0
Ameliorative potential of vitamin C and E against Roundup‐glyphosate induced genotoxicity triggering apoptosis in caprine granulosa cells	0
Investigation of the potential mutagenicity of ethyl tertiary‐butyl ether in the tumor target tissue using transgenic Big Blue Fischer 344 rats following whole body inhalation exposure	0