OOIR: Observatory of International Research

Papers

(The TQCC of Chemical Research in Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Clustering a Chemical Inventory for Safety Assessment of Fragrance Ingredients: Identifying Read-Across Analogs to Address Data Gaps	275
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology	146
Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes	117
Particulate Matter Toxicity Is Nrf2 and Mitochondria Dependent: The Roles of Metals and Polycyclic Aromatic Hydrocarbons	77
The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model	67
Neurotoxicology of Nanomaterials	65
Impact of e-Liquid Composition, Coil Temperature, and Puff Topography on the Aerosol Chemistry of Electronic Cigarettes	63
Toxicity of Carbon Nanotubes: Molecular Mechanisms, Signaling Cascades, and Remedies in Biomedical Applications	60
Review on Metal-Based Nanoparticles: Role of Reactive Oxygen Species in Renal Toxicity	56
Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products	52
Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models	52
GLORYx: Prediction of the Metabolites Resulting from Phase 1 and Phase 2 Biotransformations of Xenobiotics	52
Mitochondrial DNA Damage: Prevalence, Biological Consequence, and Emerging Pathways	49
Nuclear and Cytoplasmic Functions of Vitamin C	43
Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies	42
Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics	42
DeepDILI: Deep Learning-Powered Drug-Induced Liver Injury Prediction Using Model-Level Representation	41
Exposure to Aluminum, Cadmium, and Mercury and Autism Spectrum Disorder in Children: A Systematic Review and Meta-Analysis	40
Evaluating the Cytotoxicity of Ti₃C₂ MXene to Neural Stem Cells	38
A Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and Their Correlation with Oxidative Stress	37
Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease	37
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities	36
Prediction of the Blood–Brain Barrier (BBB) Permeability of Chemicals Based on Machine-Learning and Ensemble Methods	35
Behavior Effects of Structurally Diverse Per- and Polyfluoroalkyl Substances in Zebrafish	35
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry	35

Novel Δ⁸-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals	35
Nanomaterials and Innate Immunity: A Perspective of the Current Status in Nanosafety	34
Impact of the Physicochemical Features of TiO₂ Nanoparticles on Their In Vitro Toxicity	34
Safety Assessment of Nanomaterials for Antimicrobial Applications	34
Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies	33
A Mechanical Mechanism for Vitamin E Acetate in E-cigarette/Vaping-Associated Lung Injury	33
Advanced In Vitro Testing Strategies and Models of the Intestine for Nanosafety Research	31
Trade-off Predictivity and Explainability for Machine-Learning Powered Predictive Toxicology: An in-Depth Investigation with Tox21 Data Sets	31
Pred-Skin: A Web Portal for Accurate Prediction of Human Skin Sensitizers	31
Microcystins: Biogenesis, Toxicity, Analysis, and Control	31
Arsenic Exposure and Compromised Protein Quality Control	29
Thioproline Serves as an Efficient Antioxidant Protecting Human Cells from Oxidative Stress and Improves Cell Viability	28
Comparison of Cellular Morphological Descriptors and Molecular Fingerprints for the Prediction of Cytotoxicity- and Proliferation-Related Assays	28
Chemical and Toxicological Characterization of Vaping Emission Products from Commonly Used Vape Juice Diluents	28
Graphene-Based Materials In Vitro Toxicity and Their Structure–Activity Relationships: A Systematic Literature Review	28
Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed Caenorhabditis elegans	28
Metabolism and Toxicity of Fluorine Compounds	27
Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes	27
Ensemble Models Based on QuBiLS-MAS Features and Shallow Learning for the Prediction of Drug-Induced Liver Toxicity: Improving Deep Learning and Traditional Approaches	26
Physiologically Based Pharmacokinetic Models Predicting Renal and Hepatic Concentrations of Industrial Chemicals after Virtual Oral Doses in Rats	26
Cannabis Vaping: Existing and Emerging Modalities, Chemistry, and Pulmonary Toxicology	26
Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing	25
Thermodynamic Parameters at Bio–Nano Interface and Nanomaterial Toxicity: A Case Study on BSA Interaction with ZnO, SiO₂, and TiO₂	25
Free Radical Production and Characterization of Heat-Not-Burn Cigarettes in Comparison to Conventional and Electronic Cigarettes	24
In Silico Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate	24
Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines	23
Toxicological Responses of α-Pinene-Derived Secondary Organic Aerosol and Its Molecular Tracers in Human Lung Cell Lines	23
What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure–Activity Relationships	23
Hormesis: A General Biological Principle	23
An Evaluation of the Occupational Health Hazards of Peptide Couplers	22
In Silico Models to Predict the Perturbation of Molecular Initiating Events Related to Thyroid Hormone Homeostasis	22
EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies	22
On Some Novel Similarity-Based Functions Used in the ML-Based q-RASAR Approach for Efficient Quantitative Predictions of Selected Toxicity End Points	22
Nonclinical Evaluation of Antibacterial Oxazolidinones Contezolid and Contezolid Acefosamil with Low Serotonergic Neurotoxicity	22
Integrated Proteomics and Metabolomics Reveal the Mechanism of Nephrotoxicity Induced by Triptolide	22
Interactions of Perfluorooctanesulfonate and 6:2 Chlorinated Polyfluorinated Ether Sulfonate with Human Serum Albumin: A Comparative Study	22
Toxicity and Gene Expression Profiling of Copper- and Titanium-Based Nanoparticles Using Air–Liquid Interface Exposure	21
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials	21
Quantitative Liquid Chromatography–Nanoelectrospray Ionization–High-Resolution Tandem Mass Spectrometry Analysis of Acrolein-DNA Adducts and Etheno-DNA Adducts in Oral Cells from Cigarette Smokers and	21
Graphene Family Nanomaterials in Ocular Applications: Physicochemical Properties and Toxicity	21
Nitroreduction: A Critical Metabolic Pathway for Drugs, Environmental Pollutants, and Explosives	20
High-Throughput Screening to Identify Chemical Cardiotoxic Potential	20
Redox Activity of Flavonoids: Impact on Human Health, Therapeutics, and Chemical Safety	20
New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides	20
Role of Hydrazine-Related Chemicals in Cancer and Neurodegenerative Disease	19
Arsenite Exposure Displaces Zinc from ZRANB2 Leading to Altered Splicing	19
Deep Graph Learning with Property Augmentation for Predicting Drug-Induced Liver Injury	19
Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Strand Cleavage at an Abasic Site in DNA	19
Prediction-Inspired Intelligent Training for the Development of Classification Read-across Structure–Activity Relationship (c-RASAR) Models for Organic Skin Sensitizers: Assessment of Classification E	19
Tissue Specific Fate of Nanomaterials by Advanced Analytical Imaging Techniques - A Review	18

Volatile Organic Compounds in Mainstream Smoke of Sixty Domestic Little Cigar Products	18
Disposable Puff Bar Electronic Cigarettes: Chemical Composition and Toxicity of E-liquids and a Synthetic Coolant	18
Looking for Post-Mortem Metabolomic Standardization: Waiting for Godot—The Importance of Post-Mortem Interval in Forensic Metabolomics	18
Determination of Aristolochic Acids in Vegetables: Nephrotoxic and Carcinogenic Environmental Pollutants Contaminating a Broad Swath of the Food Supply and Driving Incidence of Balkan Endemic Nephropa	18
Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors	18
Toxicity of Water- and Organic-Soluble Wood Tar Fractions from Biomass Burning in Lung Epithelial Cells	17
Verification of Exposure to Novichok Nerve Agents Utilizing a Semitargeted Human Butyrylcholinesterase Nonapeptide Assay	17
Comparison of Genotoxicity and Cytotoxicity of Polyvinyl Chloride and Poly(methyl methacrylate) Nanoparticles on Normal Human Lung Cell Lines	16
Production of a Urinary Selenium Metabolite, Trimethylselenonium, by Thiopurine S-Methyltransferase and Indolethylamine N-Methyltransferase	16
Exploring Flow Cytometry-Based Micronucleus Scoring for Reliable Nanomaterial Genotoxicity Assessment	16
Targeting Human Islet Amyloid Polypeptide Aggregation and Toxicity in Type 2 Diabetes: An Overview of Peptide-Based Inhibitors	16
ATF3 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an N⁶-Methyladenosine-Based Epitranscriptomic Mechanism	16
Electronic Cigarette Refill Fluids Sold Worldwide: Flavor Chemical Composition, Toxicity, and Hazard Analysis	16
Hot Wires and Film Boiling: Another Look at Carbonyl Formation in Electronic Cigarettes	16
Revealing Silver Nanoparticle Uptake by Macrophages Using SR-μXRF and LA-ICP-MS	15
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration	15
Flavor-Toxicant Correlation in E-cigarettes: A Meta-Analysis	15
Determination of (R)-(+)- and (S)-(−)-Nicotine Chirality in Puff Bar E-Liquids by ¹H NMR Spectroscopy, Polarimetry, and Gas Chromatography–Mass Spectrometry	15
The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase	15
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36	15
Mechanistic Insights into the Role of Iron, Copper, and Carbonaceous Component on the Oxidative Potential of Ultrafine Particulate Matter	15
Density Functional Theory in the Prediction of Mutagenicity: A Perspective	15
HIF1, HSF1, and NRF2: Oxidant-Responsive Trio Raising Cellular Defenses and Engaging Immune System	15
Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli	15
Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties	15
Ozone-Induced DNA Damage: A Pandora’s Box of Oxidatively Modified DNA Bases	15
Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars	14
Human Metabolism and Urinary Excretion Kinetics of Nonylphenol in Three Volunteers after a Single Oral Dose	14
Metabolic Activation of Atomoxetine Mediated by Cytochrome P450 2D6	14
Reaction of Cyanide with Hg⁰-Contaminated Gold Mining Tailings Produces Soluble Mercuric Cyanide Complexes	14
Drug Safety Data Curation and Modeling in ChEMBL: Boxed Warnings and Withdrawn Drugs	14
Adsorption of Horseradish Peroxidase on Metallic Nanoparticles: Effects on Reactive Oxygen Species Detection Using 2′,7′-Dichlorofluorescin Diacetate	14
Metabolomics Profiles of Smokers from Two Ethnic Groups with Differing Lung Cancer Risk	14
Metabolic Pattern of Hepatotoxic Pyrrolizidine Alkaloids in Liver Cells	14
Mutagenic and Cancer Risk Estimation of Particulate Bound Polycyclic Aromatic Hydrocarbons from the Emission of Different Biomass Fuels	14
High-Resolution Metabolomic Assessment of Pesticide Exposure in Central Valley, California	14
Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing	14
Vaped Humectants in E-Cigarettes Are a Source of Phenols	14
Systematic Identification of Molecular Targets and Pathways Related to Human Organ Level Toxicity	14
Integrated In Silico Models for the Prediction of No-Observed-(Adverse)-Effect Levels and Lowest-Observed-(Adverse)-Effect Levels in Rats for Sub-chronic Repeated-Dose Toxicity	14
Characterizing Adduct Formation of Electrophilic Skin Allergens with Human Serum Albumin and Hemoglobin	13
Structure Activity Relationship for Fumonisin Phytotoxicity	13
Reactive Metabolites from Thiazole-Containing Drugs: Quantum Chemical Insights into Biotransformation and Toxicity	13
Protective Role of Glutathione against Peroxynitrite-Mediated DNA Damage During Acute Inflammation	13
Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury	13
Predicted AS3MT Proteins Methylate Arsenic and Support Two Major Phylogenetic AS3MT Groups	13
Teneligliptin Promotes Bile Acid Synthesis and Attenuates Lipid Accumulation in Obese Mice by Targeting the KLF15-Fgf15 Pathway	13
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats	13
Predicting Chemical-Induced Liver Toxicity Using High-Content Imaging Phenotypes and Chemical Descriptors: A Random Forest Approach	13
Carrier Solvents of Electronic Nicotine Delivery Systems Alter Pulmonary Surfactant	13
Electronic Cigarette Solvents, JUUL E-Liquids, and Biomarkers of Exposure: In Vivo Evidence for Acrolein and Glycidol in E-Cig-Derived Aerosols	13
Liver Injury Caused by Green Tea Extract in PD-1^–/– Mice: An Impaired Immune Tolerance Model for Idiosyncratic Drug-Induced Liver Injury	13
Epigenomic, Transcriptomic, and Protective Effect of Carotenoid Fucoxanthin in High Glucose-Induced Oxidative Stress in Mes13 Kidney Mesangial Cells	13
Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters	13
Exposure Assessment of Toxicologically Relevant Volatile Organic Compounds Emitted from Polymer-Based Costume Masks	12
Mass Spectrometry Analysis of DNA and Protein Adducts as Biomarkers in Human Exposure to Cigarette Smoking: Acrolein as an Example	12
In Silico Prediction of Human and Rat Liver Microsomal Stability via Machine Learning Methods	12
Exploring the Potential of ToxCast Data in Supporting Read-Across for Evaluation of Food Chemical Safety	12
PARP1 Is Required for ATM-Mediated p53 Activation and p53-Mediated Gene Expression after Ionizing Radiation	12
DNA Damage and Oxidative Stress of Tobacco Smoke Condensate in Human Bladder Epithelial Cells	12
Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity	12
Impact of Atomizer Age and Flavor on In Vitro Toxicity of Aerosols from a Third-Generation Electronic Cigarette against Human Oral Cells	12
Critical Choices in Predicting Stone Wool Biodurability: Lysosomal Fluid Compositions and Binder Effects	12
Triterpenoids as Reactive Oxygen Species Modulators of Cell Fate	12
Enhanced Disrupting Effect of Benzophenone-1 Chlorination Byproducts to the Androgen Receptor: Cell-Based Assays and Gaussian Accelerated Molecular Dynamics Simulations	12
Mechanistic Insights into the Cytotoxicity of Graphene Oxide Derivatives in Mammalian Cells	12
Biological Impacts of Reduced Graphene Oxide Affected by Protein Corona Formation	12
Effects of Arsenic on wnt/β-catenin Signaling Pathway: A Systematic Review and Meta-analysis	12
Effects of E-Cigarette Aerosols with Varying Levels of Nicotine on Biomarkers of Oxidative Stress and Inflammation in Mice	12
Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry Analysis of Apurinic/Apyrimidinic Sites in Oral Cell DNA of Cigarette Smokers, e-Cigarette Users, and Nonsmok	12
Systems Toxicology Approach for Testing Chemical Cardiotoxicity in Larval Zebrafish	12
Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease	12
COVID-19, Air Pollution, and Racial Inequity: Connecting the Dots	12
Advances on the Influence of Methylmercury Exposure during Neurodevelopment	12
Systematic Analysis of Protein Targets Associated with Adverse Events of Drugs from Clinical Trials and Postmarketing Reports	12
Binding and Metabolism of Brominated Flame Retardant β-1,2-Dibromo-4-(1,2-dibromoethyl)cyclohexane in Human Microsomal P450 Enzymes: Insights from Computational Studies	11
The Human Glyoxalase Gene Family in Health and Disease	11
Cytochrome P450 Mediated Bioactivation of Rutaevin, a Bioactive and Potentially Hepatotoxic Component of Evodia Rutaecarpa	11
Mapping Chemical Respiratory Sensitization: How Useful Are Our Current Computational Tools?	11
Metabolites of Tobacco- and E-Cigarette-Related Nitrosamines Can Drive Cu²⁺-Mediated DNA Oxidation	11

In Vivo Metabolism of Aristolochic Acid I and II in Rats Is Influenced by Their Coexposure	11
Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity	11
Nonclinical Toxicological Studies of Brazilian Red Propolis and Its Primary Botanical Source Dalbergia ecastaphyllum	11
Skin Doctor CP: Conformal Prediction of the Skin Sensitization Potential of Small Organic Molecules	11
Green Toxicology: Connecting Green Chemistry and Modern Toxicology	11
Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor Erdafitinib	11
Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells	11
Mass Spectrometric Profiling of Neuropeptides in Response to Copper Toxicity via Isobaric Tagging	11
Autophagy Plays a Protective Role in Sodium Hydrosulfide-Induced Acute Lung Injury by Attenuating Oxidative Stress and Inflammation in Rats	11
Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights	11
Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice	11
1,2-Naphthoquinone as a Poison of Human Type II Topoisomerases	11
Post-Mortem Metabolomics: A Novel Approach in Clinical Biomarker Discovery and a Potential Tool in Death Investigations	11
Strategies to Mitigate the Bioactivation of Aryl Amines	11
Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,N⁶-Ethenoadenine in Strongly Positioned Nucleosome Core Particles	11
Introduction to Special Issue: Computational Toxicology	11
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products	11
Energy Storage Materials as Emerging Nano-contaminants	11
Structure-Based Reactivity Profiles of Reactive Metabolites with Glutathione	11
Benzyl Butyl Phthalate Induced Early lncRNA H19 Regulation in C3H10T1/2 Stem Cell Line	11
Formation of Redox-Active Duroquinone from Vaping of Vitamin E Acetate Contributes to Oxidative Lung Injury	11
Quantitation of Protein Adducts of Aristolochic Acid I by Liquid Chromatography–Tandem Mass Spectrometry: A Novel Method for Biomonitoring Aristolochic Acid Exposure	11
In Silico Prediction of CYP2C8 Inhibition with Machine-Learning Methods	11
In Vitro Phase I Metabolic Profiling of the Synthetic Cannabinoids AM-694, 5F-NNEI, FUB-APINACA, MFUBINAC, and AMB-FUBINACA	10
Hepatotoxicity of Cadmium Telluride Quantum Dots Induced by Mitochondrial Dysfunction	10
Targeting Chloride Ion Channels: New Insights into the Mechanism of Action of the Marine Toxin Azaspiracid	10
Use of Cause-and-Effect Analysis to Optimize the Reliability of In Vitro Inhalation Toxicity Measurements Using an Air–Liquid Interface	10
Effects of Standardized Medicinal Plant Extracts on Drug Metabolism Mediated by CYP3A4 and CYP2D6 Enzymes	10
Probing the Hidden Role of Mitochondrial DNA Damage and Dysfunction in the Etiology of Aristolochic Acid Nephropathy	10
Novel o-Toluidine Metabolite in Rat Urine Associated with Urinary Bladder Carcinogenesis	10
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis	10
Thinking Outside the Cage: A New Hypothesis That Accounts for Variable Yields of Radicals from the Reaction of CO₂ with ONOO^–	10
Linking Coregulated Gene Modules with Polycyclic Aromatic Hydrocarbon-Related Cancer Risk in the 3D Human Bronchial Epithelium	10
Predicting DNA-Reactivity of N-Nitrosamines: A Quantum Chemical Approach	10
Biological Basis for Threshold Responses to Methylating Agents	10
Interindividual Differences in DNA Adduct Formation and Detoxification of 1,3-Butadiene-Derived Epoxide in Human HapMap Cell Lines	10
Dose-Dependent Molecular Responses of Labeo rohita to Triphenyl Phosphate	10
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)	10
Unexpected Observations: Probiotic Administration Greatly Aggravates the Reproductive Toxicity of Perfluorobutanesulfonate in Zebrafish	10
Emerging Chemicals of Health Concern in Electronic Nicotine Delivery Systems	10
Identification of an N′-Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA	10
Free-Base Nicotine Fraction α_fb in Non-Aqueous versus Aqueous Solutions: Electronic Cigarette Fluids Without versus With Dilution with Water	10
Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds	10
Vaping Cannabinoid Acetates Leads to Ketene Formation	10
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions	10
Biomarkers of DNA Oxidation Products: Links to Exposure and Disease in Public Health Studies	10
Effects of Bisphenol A and Bisphenol S Exposure at Low Doses on the Metabolome of Adolescent Male Sprague–Dawley Rats	10
Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury	10
Plasma Protein Binding Evaluations of Per- and Polyfluoroalkyl Substances for Category-Based Toxicokinetic Assessment	10
Is It Realistic to Propose Determination of a Lifetime Internal Exposome?	10
Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of Promutagenic DNA–DNA Cross-Links in Human Hapmap Cell Lines	10
Post-Mortem Changes of Methomyl in Blood with Hemoglobin	10
Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice	10
Effects of Gut Microbiome on Carcinogenic DNA Damage	10
Maternal Sodium p-Perfluorous Nonenoxybenzene Sulfonate Exposure Disturbed Lipid Metabolism and Induced an Imbalance in Tyrosine Metabolism in the F1 Generation of Mice	9
Mass Spectrometric Quantitation of Apurinic/Apyrimidinic Sites in Tissue DNA of Rats Exposed to Tobacco-Specific Nitrosamines and in Lung and Leukocyte DNA of Cigarette Smokers and Nonsmokers	9
Antagonism of GPR4 with NE 52-QQ57 and the Suppression of AGE-Induced Degradation of Type II Collagen in Human Chondrocytes	9
Metabolic Activation and Cytotoxicity of Labetalol Hydrochloride Mediated by Sulfotransferases	9
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases	9
In Vitro Glucuronidation of Caribbean Ciguatoxins in Fish: First Report of Conjugative Ciguatoxin Metabolites	9
Polystyrene Nanoplastics Induce Neutrophil Extracellular Traps in Mice Neutrophils	9
Distinct Orchestration and Dynamic Processes on γ-H2AX and p-H3 for Two Major Types of Genotoxic Chemicals Revealed by Mass Spectrometry Analysis	9
Quantifying Analogue Suitability for SAR-Based Read-Across Toxicological Assessment	9
Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs)	9
Methylmercury Can Facilitate the Formation of Dehydroalanine in Selenoenzymes: Insight from DFT Molecular Modeling	9
Quantitative Structure–Activity Relationship (QSAR) Model for the Severity Prediction of Drug-Induced Rhabdomyolysis by Using Random Forest	9
Development of a Battery of In Silico Prediction Tools for Drug-Induced Liver Injury from the Vantage Point of Translational Safety Assessment	9
Artificial Intelligence Meets Toxicology	9
Applications of CometChip for Environmental Health Studies	9
Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening	9
Organophosphorus Pesticides Promote Protein Cross-Linking	9
Cytochrome P450-Mediated Bioactivation: Implication for the Liver Injury Induced by Fraxinellone, A Bioactive Constituent from Dictamni Cortex	9
Genetically Encoded Fluorescent Redox Indicators for Unveiling Redox Signaling and Oxidative Toxicity	9
Energy Starvation in Daphnia magna from Exposure to a Lithium Cobalt Oxide Nanomaterial	9
An Updated In Silico Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Conce	9
Analysis of Nicotine and Non-nicotine Tobacco Constituents in Aqueous Smoke/Aerosol Extracts by UHPLC and Ultraperformance Convergence Chromatography–Tandem Mass Spectrometry	9
Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen	9
Modeling the Bioactivation and Subsequent Reactivity of Drugs	9
Experimental Exposure Assessment of Ionizable Organic Chemicals in In Vitro Cell-Based Bioassays	9
In Vivo Identification of Adducts from the New Hypoxia-Activated Prodrug CP-506 Using DNA Adductomics	9
In Silico Assessment of Acute Oral Toxicity for Mixtures	9
Phytochemicals in the Management of Arsenic Toxicity	9
Uptake and Removal of Uranium by and from Human Teeth	9
A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium	9
Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA	9
Chemical and Biochemical Aspects of Molecular Hydrogen in Treating Kawasaki Disease and COVID-19	9
Biomonitoring of Ambient Outdoor Air Pollutant Exposure in Humans Using Targeted Serum Albumin Adductomics	9
Investigation of 2′-Deoxyadenosine-Derived Adducts Specifically Formed in Rat Liver and Lung DNA by N′-Nitrosonornicotine Metabolism	9
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure	9
Polybrominated Diphenyl Ether Quinone Exposure Induces Atherosclerosis Progression via CD36-Mediated Lipid Accumulation, NLRP3 Inflammasome Activation, and Pyroptosis	9
Role of Protein Damage Inflicted by Dopamine Metabolites in Parkinson’s Disease: Evidence, Tools, and Outlook	9
Role of Citrus medica L. Fruits Extract in Combatting the Hematological and Hepatic Toxic Effects of Carbofuran	9
Evidence for Polyamine, Biogenic Amine, and Amino Acid Adduction Resulting from Metabolic Activation of Diosbulbin B	8
New Associations between Drug-Induced Adverse Events in Animal Models and Humans Reveal Novel Candidate Safety Targets	8
Diclofenac Sodium Triggers p53-Dependent Apoptosis in Human Corneal Epithelial Cells via ROS-Mediated Crosstalk	8