Chemical Research in Toxicology

(The TQCC of Chemical Research in Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology151
Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes122
Toxicity of Carbon Nanotubes: Molecular Mechanisms, Signaling Cascades, and Remedies in Biomedical Applications66
Impact of e-Liquid Composition, Coil Temperature, and Puff Topography on the Aerosol Chemistry of Electronic Cigarettes63
Review on Metal-Based Nanoparticles: Role of Reactive Oxygen Species in Renal Toxicity57
GLORYx: Prediction of the Metabolites Resulting from Phase 1 and Phase 2 Biotransformations of Xenobiotics54
Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models53
Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products53
Mitochondrial DNA Damage: Prevalence, Biological Consequence, and Emerging Pathways49
Nuclear and Cytoplasmic Functions of Vitamin C46
Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics45
Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies44
Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease41
DeepDILI: Deep Learning-Powered Drug-Induced Liver Injury Prediction Using Model-Level Representation41
Exposure to Aluminum, Cadmium, and Mercury and Autism Spectrum Disorder in Children: A Systematic Review and Meta-Analysis40
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry39
Prediction of the Blood–Brain Barrier (BBB) Permeability of Chemicals Based on Machine-Learning and Ensemble Methods39
A Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and Their Correlation with Oxidative Stress39
Evaluating the Cytotoxicity of Ti3C2 MXene to Neural Stem Cells38
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities37
Behavior Effects of Structurally Diverse Per- and Polyfluoroalkyl Substances in Zebrafish37
Novel Δ8-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals35
Impact of the Physicochemical Features of TiO2 Nanoparticles on Their In Vitro Toxicity35
Trade-off Predictivity and Explainability for Machine-Learning Powered Predictive Toxicology: An in-Depth Investigation with Tox21 Data Sets33
A Mechanical Mechanism for Vitamin E Acetate in E-cigarette/Vaping-Associated Lung Injury33
Microcystins: Biogenesis, Toxicity, Analysis, and Control33
Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies33
Advanced In Vitro Testing Strategies and Models of the Intestine for Nanosafety Research32
Pred-Skin: A Web Portal for Accurate Prediction of Human Skin Sensitizers32
Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes31
Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing29
Comparison of Cellular Morphological Descriptors and Molecular Fingerprints for the Prediction of Cytotoxicity- and Proliferation-Related Assays29
Arsenic Exposure and Compromised Protein Quality Control29
Cannabis Vaping: Existing and Emerging Modalities, Chemistry, and Pulmonary Toxicology29
Chemical and Toxicological Characterization of Vaping Emission Products from Commonly Used Vape Juice Diluents28
Hormesis: A General Biological Principle28
Graphene-Based Materials In Vitro Toxicity and Their Structure–Activity Relationships: A Systematic Literature Review28
Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed Caenorhabditis elegans28
Physiologically Based Pharmacokinetic Models Predicting Renal and Hepatic Concentrations of Industrial Chemicals after Virtual Oral Doses in Rats27
Metabolism and Toxicity of Fluorine Compounds27
Ensemble Models Based on QuBiLS-MAS Features and Shallow Learning for the Prediction of Drug-Induced Liver Toxicity: Improving Deep Learning and Traditional Approaches27
Thermodynamic Parameters at Bio–Nano Interface and Nanomaterial Toxicity: A Case Study on BSA Interaction with ZnO, SiO2, and TiO225
Free Radical Production and Characterization of Heat-Not-Burn Cigarettes in Comparison to Conventional and Electronic Cigarettes25
Toxicological Responses of α-Pinene-Derived Secondary Organic Aerosol and Its Molecular Tracers in Human Lung Cell Lines25
An Evaluation of the Occupational Health Hazards of Peptide Couplers24
In Silico Models to Predict the Perturbation of Molecular Initiating Events Related to Thyroid Hormone Homeostasis24
Interactions of Perfluorooctanesulfonate and 6:2 Chlorinated Polyfluorinated Ether Sulfonate with Human Serum Albumin: A Comparative Study24
On Some Novel Similarity-Based Functions Used in the ML-Based q-RASAR Approach for Efficient Quantitative Predictions of Selected Toxicity End Points24
What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure–Activity Relationships24
In Silico Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate24
Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines24
Graphene Family Nanomaterials in Ocular Applications: Physicochemical Properties and Toxicity22
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials22
Nonclinical Evaluation of Antibacterial Oxazolidinones Contezolid and Contezolid Acefosamil with Low Serotonergic Neurotoxicity22
Integrated Proteomics and Metabolomics Reveal the Mechanism of Nephrotoxicity Induced by Triptolide22
EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies22
Prediction-Inspired Intelligent Training for the Development of Classification Read-across Structure–Activity Relationship (c-RASAR) Models for Organic Skin Sensitizers: Assessment of Classification E21
Quantitative Liquid Chromatography–Nanoelectrospray Ionization–High-Resolution Tandem Mass Spectrometry Analysis of Acrolein-DNA Adducts and Etheno-DNA Adducts in Oral Cells from Cigarette Smokers and21
Nitroreduction: A Critical Metabolic Pathway for Drugs, Environmental Pollutants, and Explosives21
Redox Activity of Flavonoids: Impact on Human Health, Therapeutics, and Chemical Safety21
Role of Hydrazine-Related Chemicals in Cancer and Neurodegenerative Disease21
High-Throughput Screening to Identify Chemical Cardiotoxic Potential21
New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides20
Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Strand Cleavage at an Abasic Site in DNA20
Deep Graph Learning with Property Augmentation for Predicting Drug-Induced Liver Injury20
Toxicity of Water- and Organic-Soluble Wood Tar Fractions from Biomass Burning in Lung Epithelial Cells19
Looking for Post-Mortem Metabolomic Standardization: Waiting for Godot—The Importance of Post-Mortem Interval in Forensic Metabolomics19
Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors18
Disposable Puff Bar Electronic Cigarettes: Chemical Composition and Toxicity of E-liquids and a Synthetic Coolant18
Volatile Organic Compounds in Mainstream Smoke of Sixty Domestic Little Cigar Products18
Determination of Aristolochic Acids in Vegetables: Nephrotoxic and Carcinogenic Environmental Pollutants Contaminating a Broad Swath of the Food Supply and Driving Incidence of Balkan Endemic Nephropa18
Verification of Exposure to Novichok Nerve Agents Utilizing a Semitargeted Human Butyrylcholinesterase Nonapeptide Assay17
ATF3 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an N6-Methyladenosine-Based Epitranscriptomic Mechanism17
HIF1, HSF1, and NRF2: Oxidant-Responsive Trio Raising Cellular Defenses and Engaging Immune System17
Mechanistic Insights into the Role of Iron, Copper, and Carbonaceous Component on the Oxidative Potential of Ultrafine Particulate Matter16
Comparison of Genotoxicity and Cytotoxicity of Polyvinyl Chloride and Poly(methyl methacrylate) Nanoparticles on Normal Human Lung Cell Lines16
Hot Wires and Film Boiling: Another Look at Carbonyl Formation in Electronic Cigarettes16
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration16
High-Resolution Metabolomic Assessment of Pesticide Exposure in Central Valley, California16
Production of a Urinary Selenium Metabolite, Trimethylselenonium, by Thiopurine S-Methyltransferase and Indolethylamine N-Methyltransferase16
Targeting Human Islet Amyloid Polypeptide Aggregation and Toxicity in Type 2 Diabetes: An Overview of Peptide-Based Inhibitors16
Electronic Cigarette Refill Fluids Sold Worldwide: Flavor Chemical Composition, Toxicity, and Hazard Analysis16
Exploring Flow Cytometry-Based Micronucleus Scoring for Reliable Nanomaterial Genotoxicity Assessment16
Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing16
Determination of (R)-(+)- and (S)-(−)-Nicotine Chirality in Puff Bar E-Liquids by 1H NMR Spectroscopy, Polarimetry, and Gas Chromatography–Mass Spectrometry15
The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase15
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats15
Density Functional Theory in the Prediction of Mutagenicity: A Perspective15
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD3615
Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli15
Flavor-Toxicant Correlation in E-cigarettes: A Meta-Analysis15
Ozone-Induced DNA Damage: A Pandora’s Box of Oxidatively Modified DNA Bases15
Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties15
Mechanistic Insights into the Cytotoxicity of Graphene Oxide Derivatives in Mammalian Cells14
Exploring the Potential of ToxCast Data in Supporting Read-Across for Evaluation of Food Chemical Safety14
Metabolic Activation of Atomoxetine Mediated by Cytochrome P450 2D614
Systematic Identification of Molecular Targets and Pathways Related to Human Organ Level Toxicity14
Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters14
Adsorption of Horseradish Peroxidase on Metallic Nanoparticles: Effects on Reactive Oxygen Species Detection Using 2′,7′-Dichlorofluorescin Diacetate14
Vaped Humectants in E-Cigarettes Are a Source of Phenols14
Liver Injury Caused by Green Tea Extract in PD-1–/– Mice: An Impaired Immune Tolerance Model for Idiosyncratic Drug-Induced Liver Injury14
Reaction of Cyanide with Hg0-Contaminated Gold Mining Tailings Produces Soluble Mercuric Cyanide Complexes14
Integrated In Silico Models for the Prediction of No-Observed-(Adverse)-Effect Levels and Lowest-Observed-(Adverse)-Effect Levels in Rats for Sub-chronic Repeated-Dose Toxicity14
Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars14
Human Metabolism and Urinary Excretion Kinetics of Nonylphenol in Three Volunteers after a Single Oral Dose14
Reactive Metabolites from Thiazole-Containing Drugs: Quantum Chemical Insights into Biotransformation and Toxicity14
Metabolic Pattern of Hepatotoxic Pyrrolizidine Alkaloids in Liver Cells14
Mutagenic and Cancer Risk Estimation of Particulate Bound Polycyclic Aromatic Hydrocarbons from the Emission of Different Biomass Fuels14
Drug Safety Data Curation and Modeling in ChEMBL: Boxed Warnings and Withdrawn Drugs14
Carrier Solvents of Electronic Nicotine Delivery Systems Alter Pulmonary Surfactant13
Exposure Assessment of Toxicologically Relevant Volatile Organic Compounds Emitted from Polymer-Based Costume Masks13
Structure Activity Relationship for Fumonisin Phytotoxicity13
Enhanced Disrupting Effect of Benzophenone-1 Chlorination Byproducts to the Androgen Receptor: Cell-Based Assays and Gaussian Accelerated Molecular Dynamics Simulations13
Advances on the Influence of Methylmercury Exposure during Neurodevelopment13
Protective Role of Glutathione against Peroxynitrite-Mediated DNA Damage During Acute Inflammation13
Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury13
Effects of E-Cigarette Aerosols with Varying Levels of Nicotine on Biomarkers of Oxidative Stress and Inflammation in Mice13
Electronic Cigarette Solvents, JUUL E-Liquids, and Biomarkers of Exposure: In Vivo Evidence for Acrolein and Glycidol in E-Cig-Derived Aerosols13
Teneligliptin Promotes Bile Acid Synthesis and Attenuates Lipid Accumulation in Obese Mice by Targeting the KLF15-Fgf15 Pathway13
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products13
Predicting Chemical-Induced Liver Toxicity Using High-Content Imaging Phenotypes and Chemical Descriptors: A Random Forest Approach13
Predicted AS3MT Proteins Methylate Arsenic and Support Two Major Phylogenetic AS3MT Groups13
Characterizing Adduct Formation of Electrophilic Skin Allergens with Human Serum Albumin and Hemoglobin13
Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease13
Epigenomic, Transcriptomic, and Protective Effect of Carotenoid Fucoxanthin in High Glucose-Induced Oxidative Stress in Mes13 Kidney Mesangial Cells13
Systems Toxicology Approach for Testing Chemical Cardiotoxicity in Larval Zebrafish12
Formation of Redox-Active Duroquinone from Vaping of Vitamin E Acetate Contributes to Oxidative Lung Injury12
Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds12
COVID-19, Air Pollution, and Racial Inequity: Connecting the Dots12
Biological Impacts of Reduced Graphene Oxide Affected by Protein Corona Formation12
Systematic Analysis of Protein Targets Associated with Adverse Events of Drugs from Clinical Trials and Postmarketing Reports12
Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights12
In Silico Prediction of Human and Rat Liver Microsomal Stability via Machine Learning Methods12
Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity12
Triterpenoids as Reactive Oxygen Species Modulators of Cell Fate12
In Silico Prediction of CYP2C8 Inhibition with Machine-Learning Methods12
Vaping Cannabinoid Acetates Leads to Ketene Formation12
Strategies to Mitigate the Bioactivation of Aryl Amines12
Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity12
Impact of Atomizer Age and Flavor on In Vitro Toxicity of Aerosols from a Third-Generation Electronic Cigarette against Human Oral Cells12
Critical Choices in Predicting Stone Wool Biodurability: Lysosomal Fluid Compositions and Binder Effects12
Mass Spectrometry Analysis of DNA and Protein Adducts as Biomarkers in Human Exposure to Cigarette Smoking: Acrolein as an Example12
Post-Mortem Metabolomics: A Novel Approach in Clinical Biomarker Discovery and a Potential Tool in Death Investigations12
PARP1 Is Required for ATM-Mediated p53 Activation and p53-Mediated Gene Expression after Ionizing Radiation12
DNA Damage and Oxidative Stress of Tobacco Smoke Condensate in Human Bladder Epithelial Cells12
Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury12
Mapping Chemical Respiratory Sensitization: How Useful Are Our Current Computational Tools?12
Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry Analysis of Apurinic/Apyrimidinic Sites in Oral Cell DNA of Cigarette Smokers, e-Cigarette Users, and Nonsmok12
Metabolites of Tobacco- and E-Cigarette-Related Nitrosamines Can Drive Cu2+-Mediated DNA Oxidation11
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis11
1,2-Naphthoquinone as a Poison of Human Type II Topoisomerases11
Modeling the Bioactivation and Subsequent Reactivity of Drugs11
Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice11
Effects of Bisphenol A and Bisphenol S Exposure at Low Doses on the Metabolome of Adolescent Male Sprague–Dawley Rats11
Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells11
Introduction to Special Issue: Computational Toxicology11
Mass Spectrometric Profiling of Neuropeptides in Response to Copper Toxicity via Isobaric Tagging11
In Vivo Metabolism of Aristolochic Acid I and II in Rats Is Influenced by Their Coexposure11
Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice11
Quantitation of Protein Adducts of Aristolochic Acid I by Liquid Chromatography–Tandem Mass Spectrometry: A Novel Method for Biomonitoring Aristolochic Acid Exposure11
Skin Doctor CP: Conformal Prediction of the Skin Sensitization Potential of Small Organic Molecules11
Green Toxicology: Connecting Green Chemistry and Modern Toxicology11
Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor Erdafitinib11
The Human Glyoxalase Gene Family in Health and Disease11
Cytochrome P450 Mediated Bioactivation of Rutaevin, a Bioactive and Potentially Hepatotoxic Component of Evodia Rutaecarpa11
Emerging Chemicals of Health Concern in Electronic Nicotine Delivery Systems11
Benzyl Butyl Phthalate Induced Early lncRNA H19 Regulation in C3H10T1/2 Stem Cell Line11
Nonclinical Toxicological Studies of Brazilian Red Propolis and Its Primary Botanical Source Dalbergia ecastaphyllum11
Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen11
Quantitative Structure–Activity Relationship (QSAR) Model for the Severity Prediction of Drug-Induced Rhabdomyolysis by Using Random Forest11
In Silico Assessment of Acute Oral Toxicity for Mixtures11
Hepatotoxicity of Cadmium Telluride Quantum Dots Induced by Mitochondrial Dysfunction11
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)11
Plasma Protein Binding Evaluations of Per- and Polyfluoroalkyl Substances for Category-Based Toxicokinetic Assessment11
Autophagy Plays a Protective Role in Sodium Hydrosulfide-Induced Acute Lung Injury by Attenuating Oxidative Stress and Inflammation in Rats11
Use of Cause-and-Effect Analysis to Optimize the Reliability of In Vitro Inhalation Toxicity Measurements Using an Air–Liquid Interface10
Probing the Hidden Role of Mitochondrial DNA Damage and Dysfunction in the Etiology of Aristolochic Acid Nephropathy10
Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA10
Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs)10
Methylmercury Can Facilitate the Formation of Dehydroalanine in Selenoenzymes: Insight from DFT Molecular Modeling10
Linking Coregulated Gene Modules with Polycyclic Aromatic Hydrocarbon-Related Cancer Risk in the 3D Human Bronchial Epithelium10
Role of Citrus medica L. Fruits Extract in Combatting the Hematological and Hepatic Toxic Effects of Carbofuran10
Metabolic Activation and Cytotoxicity of Labetalol Hydrochloride Mediated by Sulfotransferases10
Effects of Standardized Medicinal Plant Extracts on Drug Metabolism Mediated by CYP3A4 and CYP2D6 Enzymes10
Unexpected Observations: Probiotic Administration Greatly Aggravates the Reproductive Toxicity of Perfluorobutanesulfonate in Zebrafish10
Identification of an N′-Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA10
Polystyrene Nanoplastics Induce Neutrophil Extracellular Traps in Mice Neutrophils10
Post-Mortem Changes of Methomyl in Blood with Hemoglobin10
Predicting DNA-Reactivity of N-Nitrosamines: A Quantum Chemical Approach10
Effects of Gut Microbiome on Carcinogenic DNA Damage10
Biomarkers of DNA Oxidation Products: Links to Exposure and Disease in Public Health Studies10
Dose-Dependent Molecular Responses of Labeo rohita to Triphenyl Phosphate10
Is It Realistic to Propose Determination of a Lifetime Internal Exposome?10
Genetically Encoded Fluorescent Redox Indicators for Unveiling Redox Signaling and Oxidative Toxicity10
Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of Promutagenic DNA–DNA Cross-Links in Human Hapmap Cell Lines10
Thinking Outside the Cage: A New Hypothesis That Accounts for Variable Yields of Radicals from the Reaction of CO2 with ONOO10
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure10
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions10
Biological Basis for Threshold Responses to Methylating Agents10
Targeting Chloride Ion Channels: New Insights into the Mechanism of Action of the Marine Toxin Azaspiracid10
Phytochemicals in the Management of Arsenic Toxicity9
Principal Metabolites in Extracts of Different Plants Responsible for Antibacterial Effects9
A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium9
In Vitro Glucuronidation of Caribbean Ciguatoxins in Fish: First Report of Conjugative Ciguatoxin Metabolites9
Investigation of 2′-Deoxyadenosine-Derived Adducts Specifically Formed in Rat Liver and Lung DNA by N′-Nitrosonornicotine Metabolism9
Biomonitoring of Ambient Outdoor Air Pollutant Exposure in Humans Using Targeted Serum Albumin Adductomics9
Analysis of Nicotine and Non-nicotine Tobacco Constituents in Aqueous Smoke/Aerosol Extracts by UHPLC and Ultraperformance Convergence Chromatography–Tandem Mass Spectrometry9
Polybrominated Diphenyl Ether Quinone Exposure Induces Atherosclerosis Progression via CD36-Mediated Lipid Accumulation, NLRP3 Inflammasome Activation, and Pyroptosis9
Development of a Battery of In Silico Prediction Tools for Drug-Induced Liver Injury from the Vantage Point of Translational Safety Assessment9
Antagonism of GPR4 with NE 52-QQ57 and the Suppression of AGE-Induced Degradation of Type II Collagen in Human Chondrocytes9
In Vivo Identification of Adducts from the New Hypoxia-Activated Prodrug CP-506 Using DNA Adductomics9
Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening9
Binimetinib Is a Potent Reversible and Time-Dependent Inhibitor of Cytochrome P450 1A29
Organophosphorus Pesticides Promote Protein Cross-Linking9
Distinct Orchestration and Dynamic Processes on γ-H2AX and p-H3 for Two Major Types of Genotoxic Chemicals Revealed by Mass Spectrometry Analysis9
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases9
Energy Starvation in Daphnia magna from Exposure to a Lithium Cobalt Oxide Nanomaterial9
Examining Metal Contents in Primary and Secondhand Aerosols Released by Electronic Cigarettes9
Role of Protein Damage Inflicted by Dopamine Metabolites in Parkinson’s Disease: Evidence, Tools, and Outlook9
The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review9
Artificial Intelligence Meets Toxicology9
Applications of CometChip for Environmental Health Studies9
Uptake and Removal of Uranium by and from Human Teeth9
Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish9
Chemical and Biochemical Aspects of Molecular Hydrogen in Treating Kawasaki Disease and COVID-199
An Updated In Silico Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Conce9
Cytochrome P450-Mediated Bioactivation: Implication for the Liver Injury Induced by Fraxinellone, A Bioactive Constituent from Dictamni Cortex9
Quantifying Analogue Suitability for SAR-Based Read-Across Toxicological Assessment9
Differential Cytotoxicity of Haloaromatic Disinfection Byproducts and Lead Co-exposures against Human Intestinal and Neuronal Cells9
Experimental Exposure Assessment of Ionizable Organic Chemicals in In Vitro Cell-Based Bioassays9
Maternal Sodium p-Perfluorous Nonenoxybenzene Sulfonate Exposure Disturbed Lipid Metabolism and Induced an Imbalance in Tyrosine Metabolism in the F1 Generation of Mice9
Mass Spectrometric Quantitation of Apurinic/Apyrimidinic Sites in Tissue DNA of Rats Exposed to Tobacco-Specific Nitrosamines and in Lung and Leukocyte DNA of Cigarette Smokers and Nonsmokers9
Identification of Formaldehyde-Induced DNA–RNA Cross-Links in the A/J Mouse Lung Tumorigenesis Model8
Role of Particulate Matter from Afghanistan and Iraq in Deployment-Related Lung Disease8
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)8
Chemistry, Pharmacology, and Toxicology of Monoisoamyl Dimercaptosuccinic Acid: A Chelating Agent for Chronic Metal Poisoning8
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells8
UVB Drives Metabolic Rewiring and Epigenetic Reprograming and Protection by Sulforaphane in Human Skin Keratinocytes8
Direct Alkylation of Deoxyguanosine by Azaserine Leads to O6-Carboxymethyldeoxyguanosine8
Insights into the Molecular Mechanisms of Liuwei Dihuang Decoction via Network Pharmacology8
Ecotoxicity Risk of Low-Dose Methylmercury Exposure to Caenorhabditis elegans: Multigenerational Toxicity and Population Discrepancy8
Saagar–A New, Extensible Set of Molecular Substructures for QSAR/QSPR and Read-Across Predictions8
New Associations between Drug-Induced Adverse Events in Animal Models and Humans Reveal Novel Candidate Safety Targets8
Metabolic Profiles of Tetrabromobisphenol A in Humans Extrapolated from Humanized-Liver Mouse Data Using a Simplified Physiologically Based Pharmacokinetic Model8
Gas Chromatography-Tandem Mass Spectrometry Verification of Sulfur Mustard Exposure in Humans through the Conversion of Protein Adducts to Free Sulfur Mustard8
Analysis of Biomarkers of DNA Damage and Mutagenicity in Mice Exposed to Acrylonitrile8
Novel Poly(ADP-ribose) Polymerase-1 Inhibitor DDHCB Inhibits Proliferation of BRCA Mutant Breast Cancer Cell In Vitro and In Vivo through a Synthetic Lethal Mechanism8
Evidence for Polyamine, Biogenic Amine, and Amino Acid Adduction Resulting from Metabolic Activation of Diosbulbin B8
Diclofenac Sodium Triggers p53-Dependent Apoptosis in Human Corneal Epithelial Cells via ROS-Mediated Crosstalk8
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System8