Chemical Research in Toxicology

Article	Citations
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology	168
Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes	144
Toxicity of Carbon Nanotubes: Molecular Mechanisms, Signaling Cascades, and Remedies in Biomedical Applications	75
Impact of e-Liquid Composition, Coil Temperature, and Puff Topography on the Aerosol Chemistry of Electronic Cigarettes	75
Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products	63
Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models	62
Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease	53
Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics	53
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities	50
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry	49
Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies	48
DeepDILI: Deep Learning-Powered Drug-Induced Liver Injury Prediction Using Model-Level Representation	48
Prediction of the Blood–Brain Barrier (BBB) Permeability of Chemicals Based on Machine-Learning and Ensemble Methods	47
Behavior Effects of Structurally Diverse Per- and Polyfluoroalkyl Substances in Zebrafish	44
Evaluating the Cytotoxicity of Ti3C2 MXene to Neural Stem Cells	42
Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes	41
Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing	40
Trade-off Predictivity and Explainability for Machine-Learning Powered Predictive Toxicology: An in-Depth Investigation with Tox21 Data Sets	40
Comparison of Cellular Morphological Descriptors and Molecular Fingerprints for the Prediction of Cytotoxicity- and Proliferation-Related Assays	38
Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies	37
Novel Δ8-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals	37
Toxicological Responses of α-Pinene-Derived Secondary Organic Aerosol and Its Molecular Tracers in Human Lung Cell Lines	34
Metabolism and Toxicity of Fluorine Compounds	33
On Some Novel Similarity-Based Functions Used in the ML-Based q-RASAR Approach for Efficient Quantitative Predictions of Selected Toxicity End Points	32
What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure–Activity Relationships	32

Hormesis: A General Biological Principle	32
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials	31
Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed Caenorhabditis elegans	31
In Silico Models to Predict the Perturbation of Molecular Initiating Events Related to Thyroid Hormone Homeostasis	30
Cannabis Vaping: Existing and Emerging Modalities, Chemistry, and Pulmonary Toxicology	30
Prediction-Inspired Intelligent Training for the Development of Classification Read-across Structure–Activity Relationship (c-RASAR) Models for Organic Skin Sensitizers: Assessment of Classification E	29
Role of Hydrazine-Related Chemicals in Cancer and Neurodegenerative Disease	29
An Evaluation of the Occupational Health Hazards of Peptide Couplers	29
Graphene-Based Materials In Vitro Toxicity and Their Structure–Activity Relationships: A Systematic Literature Review	28
Redox Activity of Flavonoids: Impact on Human Health, Therapeutics, and Chemical Safety	27
Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines	27
Nitroreduction: A Critical Metabolic Pathway for Drugs, Environmental Pollutants, and Explosives	26
High-Throughput Screening to Identify Chemical Cardiotoxic Potential	26
In Silico Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate	26
Graphene Family Nanomaterials in Ocular Applications: Physicochemical Properties and Toxicity	26
Disposable Puff Bar Electronic Cigarettes: Chemical Composition and Toxicity of E-liquids and a Synthetic Coolant	25
Nonclinical Evaluation of Antibacterial Oxazolidinones Contezolid and Contezolid Acefosamil with Low Serotonergic Neurotoxicity	25
Deep Graph Learning with Property Augmentation for Predicting Drug-Induced Liver Injury	24
Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Strand Cleavage at an Abasic Site in DNA	22
Toxicity of Water- and Organic-Soluble Wood Tar Fractions from Biomass Burning in Lung Epithelial Cells	22
HIF1, HSF1, and NRF2: Oxidant-Responsive Trio Raising Cellular Defenses and Engaging Immune System	22
Volatile Organic Compounds in Mainstream Smoke of Sixty Domestic Little Cigar Products	22
Electronic Cigarette Refill Fluids Sold Worldwide: Flavor Chemical Composition, Toxicity, and Hazard Analysis	22
Looking for Post-Mortem Metabolomic Standardization: Waiting for Godot—The Importance of Post-Mortem Interval in Forensic Metabolomics	22
Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds	21
Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors	21
Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity	21
Plasma Protein Binding Evaluations of Per- and Polyfluoroalkyl Substances for Category-Based Toxicokinetic Assessment	20
ATF3 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an N6-Methyladenosine-Based Epitranscriptomic Mechanism	20
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products	20
The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase	20
Mechanistic Insights into the Role of Iron, Copper, and Carbonaceous Component on the Oxidative Potential of Ultrafine Particulate Matter	19
High-Resolution Metabolomic Assessment of Pesticide Exposure in Central Valley, California	19
Predicting DNA-Reactivity of N-Nitrosamines: A Quantum Chemical Approach	19
Determination of (R)-(+)- and (S)-(−)-Nicotine Chirality in Puff Bar E-Liquids by 1H NMR Spectroscopy, Polarimetry, and Gas Chromatography–Mass Spectrometry	18
Flavor-Toxicant Correlation in E-cigarettes: A Meta-Analysis	18
Triterpenoids as Reactive Oxygen Species Modulators of Cell Fate	18
Comparison of Genotoxicity and Cytotoxicity of Polyvinyl Chloride and Poly(methyl methacrylate) Nanoparticles on Normal Human Lung Cell Lines	18
Verification of Exposure to Novichok Nerve Agents Utilizing a Semitargeted Human Butyrylcholinesterase Nonapeptide Assay	18
Reactive Metabolites from Thiazole-Containing Drugs: Quantum Chemical Insights into Biotransformation and Toxicity	17
Drug Safety Data Curation and Modeling in ChEMBL: Boxed Warnings and Withdrawn Drugs	17
Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights	17
Liver Injury Caused by Green Tea Extract in PD-1–/– Mice: An Impaired Immune Tolerance Model for Idiosyncratic Drug-Induced Liver Injury	17
Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters	17
Exploring the Potential of ToxCast Data in Supporting Read-Across for Evaluation of Food Chemical Safety	17
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration	17
Formation of Redox-Active Duroquinone from Vaping of Vitamin E Acetate Contributes to Oxidative Lung Injury	16
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats	16
Mass Spectrometry Analysis of DNA and Protein Adducts as Biomarkers in Human Exposure to Cigarette Smoking: Acrolein as an Example	16
Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease	16

Effects of E-Cigarette Aerosols with Varying Levels of Nicotine on Biomarkers of Oxidative Stress and Inflammation in Mice	16
Ozone-Induced DNA Damage: A Pandora’s Box of Oxidatively Modified DNA Bases	16
Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties	16
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases	16
Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars	15
Human Metabolism and Urinary Excretion Kinetics of Nonylphenol in Three Volunteers after a Single Oral Dose	15
Mapping Chemical Respiratory Sensitization: How Useful Are Our Current Computational Tools?	15
In Silico Prediction of Human and Rat Liver Microsomal Stability via Machine Learning Methods	15
Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli	15
Systematic Identification of Molecular Targets and Pathways Related to Human Organ Level Toxicity	15
Polystyrene Nanoplastics Induce Neutrophil Extracellular Traps in Mice Neutrophils	15
Adsorption of Horseradish Peroxidase on Metallic Nanoparticles: Effects on Reactive Oxygen Species Detection Using 2′,7′-Dichlorofluorescin Diacetate	15
The Human Glyoxalase Gene Family in Health and Disease	15
Effects of Bisphenol A and Bisphenol S Exposure at Low Doses on the Metabolome of Adolescent Male Sprague–Dawley Rats	14
Metabolic Activation of Atomoxetine Mediated by Cytochrome P450 2D6	14
Mutagenic and Cancer Risk Estimation of Particulate Bound Polycyclic Aromatic Hydrocarbons from the Emission of Different Biomass Fuels	14
Metabolic Pattern of Hepatotoxic Pyrrolizidine Alkaloids in Liver Cells	14
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis	14
Skin Doctor CP: Conformal Prediction of the Skin Sensitization Potential of Small Organic Molecules	14
Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice	14
DNA Damage and Oxidative Stress of Tobacco Smoke Condensate in Human Bladder Epithelial Cells	14
Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury	14
Quantum-Mechanical Approach to Predicting the Carcinogenic Potency of N-Nitroso Impurities in Pharmaceuticals	14
Epigenomic, Transcriptomic, and Protective Effect of Carotenoid Fucoxanthin in High Glucose-Induced Oxidative Stress in Mes13 Kidney Mesangial Cells	14
Exposure Assessment of Toxicologically Relevant Volatile Organic Compounds Emitted from Polymer-Based Costume Masks	14
Vaping Cannabinoid Acetates Leads to Ketene Formation	14
Enhanced Disrupting Effect of Benzophenone-1 Chlorination Byproducts to the Androgen Receptor: Cell-Based Assays and Gaussian Accelerated Molecular Dynamics Simulations	14
Advances on the Influence of Methylmercury Exposure during Neurodevelopment	14
Systematic Analysis of Protein Targets Associated with Adverse Events of Drugs from Clinical Trials and Postmarketing Reports	14
Cytochrome P450 Mediated Bioactivation of Rutaevin, a Bioactive and Potentially Hepatotoxic Component of Evodia Rutaecarpa	14
Predicted AS3MT Proteins Methylate Arsenic and Support Two Major Phylogenetic AS3MT Groups	14
Post-Mortem Metabolomics: A Novel Approach in Clinical Biomarker Discovery and a Potential Tool in Death Investigations	14
Electronic Cigarette Solvents, JUUL E-Liquids, and Biomarkers of Exposure: In Vivo Evidence for Acrolein and Glycidol in E-Cig-Derived Aerosols	13
Structure Activity Relationship for Fumonisin Phytotoxicity	13
Role of Citrus medica L. Fruits Extract in Combatting the Hematological and Hepatic Toxic Effects of Carbofuran	13
Biological Impacts of Reduced Graphene Oxide Affected by Protein Corona Formation	13
Introduction to Special Issue: Computational Toxicology	13
Chemical and Biochemical Aspects of Molecular Hydrogen in Treating Kawasaki Disease and COVID-19	13
Quantifying Analogue Suitability for SAR-Based Read-Across Toxicological Assessment	13
Examining Metal Contents in Primary and Secondhand Aerosols Released by Electronic Cigarettes	13
COVID-19, Air Pollution, and Racial Inequity: Connecting the Dots	13
Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor Erdafitinib	13
Use of Cause-and-Effect Analysis to Optimize the Reliability of In Vitro Inhalation Toxicity Measurements Using an Air–Liquid Interface	13
Autophagy Plays a Protective Role in Sodium Hydrosulfide-Induced Acute Lung Injury by Attenuating Oxidative Stress and Inflammation in Rats	13
AI/ML Models to Predict the Severity of Drug-Induced Liver Injury for Small Molecules	13
Nonclinical Toxicological Studies of Brazilian Red Propolis and Its Primary Botanical Source Dalbergia ecastaphyllum	13
Role of Protein Damage Inflicted by Dopamine Metabolites in Parkinson’s Disease: Evidence, Tools, and Outlook	13
Quantitative Structure–Activity Relationship (QSAR) Model for the Severity Prediction of Drug-Induced Rhabdomyolysis by Using Random Forest	13
Use of Chicken Embryo Model in Toxicity Studies of Endocrine-Disrupting Chemicals and Nanoparticles	13
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)	13
Carrier Solvents of Electronic Nicotine Delivery Systems Alter Pulmonary Surfactant	13
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells	12
A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies	12
Quantitation of Protein Adducts of Aristolochic Acid I by Liquid Chromatography–Tandem Mass Spectrometry: A Novel Method for Biomonitoring Aristolochic Acid Exposure	12
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions	12
Methylmercury Can Facilitate the Formation of Dehydroalanine in Selenoenzymes: Insight from DFT Molecular Modeling	12
Development of a Battery of In Silico Prediction Tools for Drug-Induced Liver Injury from the Vantage Point of Translational Safety Assessment	12
In Silico Assessment of Acute Oral Toxicity for Mixtures	12
Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity	12
Chemistry, Pharmacology, and Toxicology of Monoisoamyl Dimercaptosuccinic Acid: A Chelating Agent for Chronic Metal Poisoning	12
Machine Learning Model for Screening Thyroid Stimulating Hormone Receptor Agonists Based on Updated Datasets and Improved Applicability Domain Metrics	12
Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry Analysis of Apurinic/Apyrimidinic Sites in Oral Cell DNA of Cigarette Smokers, e-Cigarette Users, and Nonsmok	12
Critical Choices in Predicting Stone Wool Biodurability: Lysosomal Fluid Compositions and Binder Effects	12
In Silico Prediction of CYP2C8 Inhibition with Machine-Learning Methods	12
Green Toxicology: Connecting Green Chemistry and Modern Toxicology	12
Phytochemicals in the Management of Arsenic Toxicity	12
Predicting the Mitochondrial Toxicity of Small Molecules: Insights from Mechanistic Assays and Cell Painting Data	12
Dose-Dependent Molecular Responses of Labeo rohita to Triphenyl Phosphate	12
Comparative Effects of Brominated Flame Retardants BDE-209, TBBPA, and HBCD on Neurotoxicity in Mice	12
1,2-Naphthoquinone as a Poison of Human Type II Topoisomerases	12
Toxicity and Metabolomic Impact of Cobalt, Chromium, and Nickel Exposure on HepaRG Hepatocytes	12
Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen	12
Modeling the Bioactivation and Subsequent Reactivity of Drugs	12
Targeting Chloride Ion Channels: New Insights into the Mechanism of Action of the Marine Toxin Azaspiracid	12
Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells	12
Linking Coregulated Gene Modules with Polycyclic Aromatic Hydrocarbon-Related Cancer Risk in the 3D Human Bronchial Epithelium	11
In Vivo Identification of Adducts from the New Hypoxia-Activated Prodrug CP-506 Using DNA Adductomics	11
Uptake and Removal of Uranium by and from Human Teeth	11
Identification of Formaldehyde-Induced DNA–RNA Cross-Links in the A/J Mouse Lung Tumorigenesis Model	11
Probing the Hidden Role of Mitochondrial DNA Damage and Dysfunction in the Etiology of Aristolochic Acid Nephropathy	11

Identification of an N′-Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA	11
Biomonitoring of Ambient Outdoor Air Pollutant Exposure in Humans Using Targeted Serum Albumin Adductomics	11
Polybrominated Diphenyl Ether Quinone Exposure Induces Atherosclerosis Progression via CD36-Mediated Lipid Accumulation, NLRP3 Inflammasome Activation, and Pyroptosis	11
Biomarkers of DNA Oxidation Products: Links to Exposure and Disease in Public Health Studies	11
Maternal Sodium p-Perfluorous Nonenoxybenzene Sulfonate Exposure Disturbed Lipid Metabolism and Induced an Imbalance in Tyrosine Metabolism in the F1 Generation of Mice	11
Mass Spectrometric Profiling of Neuropeptides in Response to Copper Toxicity via Isobaric Tagging	11
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)	11
DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B1-Induced Formamidopyrimidine Guanine Adduct	11
Benzyl Butyl Phthalate Induced Early lncRNA H19 Regulation in C3H10T1/2 Stem Cell Line	11
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure	11
Quantitative In Vitro-to-In Vivo Extrapolation: Nominal versus Freely Dissolved Concentration	11
Effect of Titanium Dioxide Nanoparticles on Mammalian Cell Cycle In Vitro: A Systematic Review and Meta-Analysis	11
Integrated QSAR and Adverse Outcome Pathway Analysis of Chemicals Released on 3D Printing Using Acrylonitrile Butadiene Styrene	11
Ecotoxicity Risk of Low-Dose Methylmercury Exposure to Caenorhabditis elegans: Multigenerational Toxicity and Population Discrepancy	11
Saagar–A New, Extensible Set of Molecular Substructures for QSAR/QSPR and Read-Across Predictions	11
Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of Promutagenic DNA–DNA Cross-Links in Human Hapmap Cell Lines	11
Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic Site in Duplex DNA	11
Post-Mortem Changes of Methomyl in Blood with Hemoglobin	11
Probing the Interactions of Perfluorocarboxylic Acids of Various Chain Lengths with Human Serum Albumin: Calorimetric and Spectroscopic Investigations	10
A New CSRML Structure-Based Fingerprint Method for Profiling and Categorizing Per- and Polyfluoroalkyl Substances (PFAS)	10
A Wide Range of Flavoring–Carrier Fluid Adducts Form in E-Cigarette Liquids	10
Aldehyde-Associated Mutagenesis─Current State of Knowledge	10
Artificial Intelligence Meets Toxicology	10
Metabolic Activation and Cytotoxicity of Labetalol Hydrochloride Mediated by Sulfotransferases	10
Chronic Exposure to Climbazole Induces Oxidative Stress and Sex Hormone Imbalance in the Testes of Male Zebrafish	10
Dissolution Rate of Nanomaterials Determined by Ions and Particle Size under Lysosomal Conditions: Contributions to Standardization of Simulant Fluids and Analytical Methods	10
Analysis of Nicotine and Non-nicotine Tobacco Constituents in Aqueous Smoke/Aerosol Extracts by UHPLC and Ultraperformance Convergence Chromatography–Tandem Mass Spectrometry	10
Genetically Encoded Fluorescent Redox Indicators for Unveiling Redox Signaling and Oxidative Toxicity	10
Equivariant Graph Neural Networks for Toxicity Prediction	10
Influence of Nitrite on Formation of Tobacco-Specific Nitrosamines in Electronic Cigarette Liquids and Aerosols	10
The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review	10
In Vitro Glucuronidation of Caribbean Ciguatoxins in Fish: First Report of Conjugative Ciguatoxin Metabolites	10
Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment	10
Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation	10
Investigation of 2′-Deoxyadenosine-Derived Adducts Specifically Formed in Rat Liver and Lung DNA by N′-Nitrosonornicotine Metabolism	10
A Review of Stable Isotope Labeling and Mass Spectrometry Methods to Distinguish Exogenous from Endogenous DNA Adducts and Improve Dose–Response Assessments	10
Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening	10
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells	10
A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium	10
Coexposure to Inhaled Aldehydes or Carbon Dioxide Enhances the Carcinogenic Properties of the Tobacco-Specific Nitrosamine 4-Methylnitrosamino-1-(3-pyridyl)-1-butanone in the A/J Mouse Lung	9
Combining In Vivo Data with In Silico Predictions for Modeling Hepatic Steatosis by Using Stratified Bagging and Conformal Prediction	9
Principal Metabolites in Extracts of Different Plants Responsible for Antibacterial Effects	9
Toward Realistic Dosimetry In Vitro: Determining Effective Concentrations of Test Substances in Cell Culture and Their Prediction by an In Silico Mass Balance Model	9
Organophosphorus Pesticides Promote Protein Cross-Linking	9
Quercetin Attenuates Vascular Endothelial Dysfunction in Atherosclerotic Mice by Inhibiting Myeloperoxidase and NADPH Oxidase Function	9
New Associations between Drug-Induced Adverse Events in Animal Models and Humans Reveal Novel Candidate Safety Targets	9
Energy Starvation in Daphnia magna from Exposure to a Lithium Cobalt Oxide Nanomaterial	9
Omarigliptin Prevents TNF-α-Induced Cellular Senescence in Rat Aorta Vascular Smooth Muscle Cells	9
A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium	9
Metabolic Activation of Gemfibrozil Mediated by Cytochrome P450 Enzymes and Sulfotransferases	9
High-Throughput Screening of ToxCast PFAS Chemical Library for Potential Inhibitors of the Human Sodium Iodide Symporter	9
Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities	9
Attaching a Dipeptide to Fullerene as an Antioxidant Hybrid against DNA Oxidation	9
Metabolic Profiles of Tetrabromobisphenol A in Humans Extrapolated from Humanized-Liver Mouse Data Using a Simplified Physiologically Based Pharmacokinetic Model	9
Diclofenac Sodium Triggers p53-Dependent Apoptosis in Human Corneal Epithelial Cells via ROS-Mediated Crosstalk	9
Quantitation of DNA Adducts Resulting from Acrolein Exposure and Lipid Peroxidation in Oral Cells of Cigarette Smokers from Three Racial/Ethnic Groups with Differing Risks for Lung Cancer	9
An Updated In Silico Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Conce	9
Quantitation of Nitration, Chlorination, and Oxidation in Hemoglobin of Breast Cancer Patients by Nanoflow Liquid Chromatography Tandem Mass Spectrometry	9
Experimental Approaches for Investigating Disulfide-Based Redox Relays in Cells	9
Comparative Exposure Assessment of Potential Health Risks through the Consumption of Vegetables Irrigated by Freshwater/Wastewater: Gujranwala, Pakistan	9
Validation of Acetylcholinesterase Inhibition Machine Learning Models for Multiple Species	9
Network Pharmacology Combined with Metabolomics Approach to Investigate the Toxicity Mechanism of Paclobutrazol	9
Kinetics of Aldehyde Flavorant-Acetal Formation in E-Liquids with Different E-Cigarette Solvents and Common Additives Studied by 1H NMR Spectroscopy	9
Evaluation of Recombinant CYP3A4 Variants on the Metabolism of Oxycodone In Vitro	9
Binimetinib Is a Potent Reversible and Time-Dependent Inhibitor of Cytochrome P450 1A2	9
UVB Drives Metabolic Rewiring and Epigenetic Reprograming and Protection by Sulforaphane in Human Skin Keratinocytes	9
Recent Advances in the Detection of Food Toxins Using Mass Spectrometry	9
Role of Particulate Matter from Afghanistan and Iraq in Deployment-Related Lung Disease	9
Perspectives of Genetic Damage and Epigenetic Alterations by Hexavalent Chromium: Time Evolution Based on a Bibliometric Analysis	9
Insights into the Molecular Mechanisms of Liuwei Dihuang Decoction via Network Pharmacology	9
An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects	9
Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective	9
Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following Inhalation Exposure to 1,3-Butadiene	9
Assessment of Drug-Induced Liver Injury through Cell Morphology and Gene Expression Analysis	9
Are Some Metals in Tattoo Inks Harmful to Health? An Analytical Approach	9
Carbonyl Emissions and Heating Temperatures across 75 Nominally Identical Electronic Nicotine Delivery System Products: Do Manufacturing Variations Drive Pulmonary Toxicant Exposure?	9
Ambient Fine Particulate Matter and Cancer: Current Evidence and Future Perspectives	8
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System	8
Antidepressant Actions of Ketamine: Potential Role of L-Type Calcium Channels	8
High-Throughput Assessment of the Abiotic Stability of Test Chemicals in In Vitro Bioassays	8
Extending the HSA-Cys34-Adductomics Pipeline to Modifications at Lys525	8
Nucleophilic Thiol Proteins Bind Covalently to Abasic Sites in DNA	8
Short Preirradiation of TiO2 Nanoparticles Increases Cytotoxicity on Human Lung Coculture System	8
Making the Case for Quantum Mechanics in Predictive Toxicology─Nearly 100 Years Too Late?	8
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models	8
Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative	8
Bovine Serum Albumin as a Potential Carrier for the Protection of Bioactive Quercetin and Inhibition of Cu(II) Toxicity	8
Assessment of the Exposure to NNN in the Plasma of Smokeless Tobacco Users	8
Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy	8
Toxic Chemical Formation during Vaping of Ethyl Ester Flavor Additives: A Chemical Kinetic Modeling Study	8
Direct Alkylation of Deoxyguanosine by Azaserine Leads to O6-Carboxymethyldeoxyguanosine	8
Underlying Mechanisms of Allopurinol in Eliminating Renal Toxicity Induced by Melamine–Uric Acid Complex Formation: A Computational Study	8
Elucidation of in Vitro Chlorinated Tyrosine Adducts in Blood Plasma as Selective Biomarkers of Chlorine Exposure	8
Differential Roles of Water-Insoluble and Water-Soluble Fractions of Diesel Exhaust Particles in the Development of Adverse Health Effects Due to Chronic Instillation of Diesel Exhaust Particles	8
Integrative Analysis of Transcriptomic and Metabolomic Data for Identification of Pathways Related to Matrine-Induced Hepatotoxicity	8