Chemical Research in Toxicology

Article	Citations
Issue Publication Information	89
Elevating Research and Careers in the Development of Safer Drugs through Artificial Intelligence	80
Identification of an Epoxide Metabolite of Amitriptyline In Vitro and In Vivo	76
Protein Haptenation and Its Role in Allergy	65
Issue Editorial Masthead	64
In Vitro and In Vivo Analysis of Fentanyl and Fentalog Metabolites using Hyphenated Chromatographic Techniques: A Review	61
Issue Editorial Masthead	61
Issue Publication Information	60
Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs	51
A Weakly Supervised Deep Learning Framework for Whole Slide Classification to Facilitate Digital Pathology in Animal Study	50
Coumarin-Based Noncytotoxicity Fluorescent Dye for Tracking Actin Protein in In-Vivo Imaging	46
Novel 4-Hydroxybenzyl Adducts in Human Hemoglobin: Structures and Mechanisms of Formation	45
Capture of Electrophilic Quinones in the Extracellular Space: Evidence for a Phase Zero Reaction	44
Recent Advances in DNA Lesion Mapping and Repair Mechanisms	44
Oxidative Deformylation of the Predominant DNA Lesion 5-Formyl-2′-deoxyuridine	42
Surfactant Coformulants in Glyphosate-Based Herbicides: Current Gaps, and Paths Forward in Human Biomonitoring	41
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)	40
Advances in Metabolism and Metabolic Toxicology of Quinoxaline 1,4-Di-N-oxides	40
Predicting Liver-Related In Vitro Endpoints with Machine Learning to Support Early Detection of Drug-Induced Liver Injury	36
Systematic Investigation of CYP3A4 Using Side-by-Side Comparisons of Apo, Active Site, and Allosteric-Bound States	34
Issue Publication Information	33
Dissecting the Enantioselective Neurotoxicity of Isocarbophos: Chiral Insight from Cellular, Molecular, and Computational Investigations	33
Electrochemical Simulation of the Oxidative Capsaicin Metabolism	33
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells	32
Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy	31

A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies	31
Mechanistic Insights into Toxicity of Titanium Dioxide Nanoparticles at the Micro- and Macro-levels	31
LA-ICP-MS and Immunohistochemical Staining with Lanthanide-Labeled Antibodies to Study the Uptake of CeO2 Nanoparticles by Macrophages in Tissue Sections	30
Direct Alkylation of Deoxyguanosine by Azaserine Leads to O6-Carboxymethyldeoxyguanosine	29
Issue Editorial Masthead	28
Response to ‘Comments on “Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of Commercial Little Cigars”’ Letter to Editor	28
Issue Editorial Masthead	27
Quantum-Mechanical Approach to Predicting the Carcinogenic Potency of N-Nitroso Impurities in Pharmaceuticals	26
Conditional Binding of Arsenic Trioxide (ATO) to Cysteine-Rich Zinc Finger Motifs within RBCC Domain of PML Protein	25
Computational Prediction of Metabolic α-Carbon Hydroxylation Potential ofN-Nitrosamines: Overcoming Data Limitations for Carcinogenicity Assessment	25
Assessing the Toxicity of Terpene- and Amino Acid-Based Natural Deep Eutectic Solvents	25
Prediction of Cytochrome P450 Substrates Using the Explainable Multitask Deep Learning Models	25
Quantum Mechanical Assessment of Nitrosamine Potency	25
Nonclinical Safety Signals in PharmaPendium Improve the Predictability of Human Drug-Induced Liver Injury	24
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry	24
Extracellular Vesicles from Human Plasma Show a Distinctive Proteome and miRNome Profile in Patients with Severe Cutaneous Adverse Reactions	24
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models	23
Mass Spectrometry-Based Metabolic Profiling of Urinary Metabolites of N′-Nitrosonornicotine (NNN) in the Rat	22
Advancing Drug Safety in Drug Development: Bridging Computational Predictions for Enhanced Toxicity Prediction	22
Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash	22
The Toxicity of Poly(acrylonitrile-styrene–butadiene) Microplastics toward Hyalella azteca Is Associated with Biofragmentation and Oxidative Stress	21
Photosensitized Oxidation of Free and Peptide Tryptophan to N-Formylkynurenine	21
Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:01	21
Modeling the Toxicokinetics of Suspensions of Soluble Metallic Nanomaterials	21
ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics	21
Issue Editorial Masthead	20
Structural Elucidation of Agrochemical Metabolic Transformation Products Based on Infrared Ion Spectroscopy to Improve In Silico Toxicity Assessment	20
Issue Editorial Masthead	20
Metals in Cannabis Vaporizer Aerosols: Sources, Possible Mechanisms, and Exposure Profiles	20
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System	20
2,2′,4,4′-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation	19
HDAC6-Mediated NLRP3 Inflammasome Activation Is Involved in Nickel Nanoparticle-Induced Pulmonary Inflammation and Fibrosis	19
Underlying Mechanisms of Allopurinol in Eliminating Renal Toxicity Induced by Melamine–Uric Acid Complex Formation: A Computational Study	19
LC–MS/MS Analysis of Reaction Products of Arginine/Methylarginines with Methylglyoxal/Glyoxal	19
Telmisartan Mitigates High-Glucose-Induced Injury in Renal Glomerular Endothelial Cells (rGECs) and Albuminuria in Diabetes Mice	19
Issue Publication Information	18
Comment on Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products	18
Simultaneous Quantification of Biomarkers for Bis-(2-chloroethyl) Sulfide and 1,2-Bis(2-chloroethylthio) Ethane Exposure in Human Urine at Trace Exposure Levels by Gas Chromatography Tandem Mass Spect	18
Federated Learning in Computational Toxicology: An Industrial Perspective on the Effiris Hackathon	18
Black Raspberry Extract Enhances Glutathione Conjugation of the Fjord-Region Diol Epoxide Derived from the Tobacco Carcinogen Dibenzo[def,p]chrysene in Human Oral Cells	17
Effects of Bisphenol A and Bisphenol S Exposure at Low Doses on the Metabolome of Adolescent Male Sprague–Dawley Rats	17
Heterogeneous Oxidation Products of Fine Particulate Isoprene Epoxydiol-Derived Methyltetrol Sulfates Increase Oxidative Stress and Inflammatory Gene Responses in Human Lung Cells	17
Acrylamide-Aggravated Liver Injury by Activating Endoplasmic Reticulum Stress in Female Mice with Diabetes	17
Nontargeted Analysis in Tobacco Research: Challenges and Opportunities	17
Cytocompatibility of Ti3C2Tx MXene with Red Blood Cells and Human Umbilical Vein Endothelial Cells and the Underlying Mechanisms	17
Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities	16
Nucleophilic Thiol Proteins Bind Covalently to Abasic Sites in DNA	16
Metabolism-Coupled Cell-Independent Acetylcholinesterase Activity Assay for Evaluation of the Effects of Chlorination on Diazinon Toxicity	16
Quantitation of γ-Glutamylcysteine–Formaldehyde Conjugate in Formaldehyde- and Oxidative Stress-Exposed Cells by Liquid Chromatography–Tandem Mass Spectrometry	16
Aldehyde-Associated Mutagenesis─Current State of Knowledge	16

Issue Editorial Masthead	16
Free Radicals in Little Cigar Mainstream Smoke and the Potential Influence of Flavoring Chemicals on Free Radical Production	16
Chemoproteomic Approach for Identifying Nuclear Arsenite-Binding Proteins	16
Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor Erdafitinib	16
Zebrafish Larvae as a Predictive Model for the Risk of Chemical-Induced Cholestasis: Phenotypic Evaluation and Nomogram Formation	16
Capturing Differential Quality of Experimental Evidence in a Predictive Quantum-Mechanical Model for Respiratory Sensitization	15
Melatonin Vapes Contain Potential Contaminants and Alter the Human Bronchial Epithelial Transcriptome	15
Diethylhexyl Phthalate and Bisphenol A Promote Vincristine and Tamoxifen Resistancein Vitro	15
The Genotoxicity of Stress	15
Issue Editorial Masthead	15
Dopamine Release Impairments Accompany Locomotor and Cognitive Deficiencies in Rotenone-Treated Parkinson’s Disease Model Zebrafish	15
Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition	15
Issue Editorial Masthead	15
Issue Publication Information	15
Metabolic Activation of Atomoxetine Mediated by Cytochrome P450 2D6	15
CYP3A4-Mediated Metabolic Activation and Cytotoxicity of Chlortoluron	15
Photo-oxidation and Photoreduction of Catechols by Chlorophyll Metabolites and Methylene Blue	15
Call for Papers for a Special Issue on Mass Spectrometry Advances for Environmental and Human Health	15
Integrative Data Mining Approach: Case Study with Adverse Outcome Pathway Network Leading to Pulmonary Fibrosis	15
Metabolic Activation and Cytotoxicity of Propafenone Mediated by CYP2D6	14
Methylmercury Can Facilitate the Formation of Dehydroalanine in Selenoenzymes: Insight from DFT Molecular Modeling	14
Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing	14
Binding of Per- and Polyfluoroalkyl Substances to β-Lactoglobulin from Bovine Milk	14
Correction to “Use of Structural Alerts for Reactive Metabolites in the Application SpotRM”	14
Photosensitizing Properties of the Topical Retinoid Drug Adapalene	14
Novel In Vitro Intestinal Microbiome Model to Study Lipidomic and Metabolomic Adaptations Due to Exposure to Glyphosate, Perfluorooctanoic Acid, and Docusate Sodium	14
Cell Painting and Chemical Structure Read-Across Can Complement Each Other for Rat Acute Oral Toxicity Prediction in Chemical Early Derisking	14
A Photoinducible DNA Cross-Linking Agent with Potent Cytotoxicity and Selectivity Toward Triple-Negative Breast Cancer Cell Line	14
Increased JUUL Emissions from Initial Puffs after Removing and Reinserting Pod	14
Role of Human Aldo–Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene	14
A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of l-Carnosine	14
Butyl Benzyl Phthalate Promotes Adipogenesis in 3T3-L1 Cells via the miRNA-34a-5p Signaling Pathway in the Absence of Exogenous Adipogenic Stimuli	14
Correction to Exposure to Aluminum, Cadmium, and Mercury and Autism Spectrum Disorder in Children: A Systematic Review and Meta-Analysis	13
Issue Editorial Masthead	13
Issue Publication Information	13
Spatiotemporal Visualization of Paraquat Distribution, Toxicokinetics, and Its Detoxification in Zebrafish Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging	13
Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer	13
Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA Adductomics	13
Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC–MS Analyses	13
Natural Products in Redox Toxicology	13
Mechanisms Mediating the Combined Toxicity of Paraquat and Maneb in SH-SY5Y Neuroblastoma Cells	13
Activation of V-Domain Immunoglobulin Suppressor of T-Cell Activation by Baloxavir Marboxil Ameliorates Systemic Lupus Erythematosus through Inhibiting Lysophosphatidylcholine/CD40 Ligand	13
Introduction to the Special Issue: AI Meets Toxicology	13
Issue Publication Information	13
One-Week Kava Dietary Supplementation Increases Both Urinary N- and O-Glucuronides of NNAL, a Lung Carcinogen Major Metabolite, among Smokers	13
Hazard Profiling of Commercially Relevant Quantum Dot Components Revealed Synergistic Interactions between Heavy Metals and Polymers	13
Correction to “Structure-Based Reactivity Profiles of Reactive Metabolites with Glutathione”	13
New Aminobiphenylcysteine Derivatives in Globin and Urine of Rats Dosed with 4-Aminobiphenyl, a Tobacco Smoke Carcinogen	12
Issue Editorial Masthead	12
Computer-Aided Discovery and Redesign for Respiratory Sensitization: A Tiered Mechanistic Model to Deliver Robust Performance Across a Diverse Chemical Space	12
Furan Metabolites Are Elevated in Users of Various Tobacco Products and Cannabis	12
Dissolution Rate of Nanomaterials Determined by Ions and Particle Size under Lysosomal Conditions: Contributions to Standardization of Simulant Fluids and Analytical Methods	12
Issue Publication Information	12
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure	12
Interindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation	12
Cannabidiol Toxicity Driven by Hydroxyquinone Formation	12
Women in Toxicology Special Issue	12
Determination of (R)-(+)- and (S)-(−)-Nicotine Chirality in Puff Bar E-Liquids by 1H NMR Spectroscopy, Polarimetry, and Gas Chromatography–Mass Spectrometry	12
Nicotine Dosimetry in Evaluating Electronic Cigarettes Compared to Cigarette Smoking: Implications for Tobacco Regulatory Science	12
Examining Metal Contents in Primary and Secondhand Aerosols Released by Electronic Cigarettes	12
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials	11
Cadmium Exposure and Cardiovascular Diseases	11
Tox24 Challenge	11
Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective	11
Advancements of Xenobiotic Toxicity Screening for the Advancement of Human Health	11
Long Noncoding RNA MIAT Modulates Chronic Retinal Ischemia-Reperfusion Injury in Mice via the microRNA-203-3p/SNAI2 Axis	11
Histotoxicity of AIEgen Based on Triphenylamine for the Simultaneous and Discriminatory Sensing of Hg2+ and Ag+ Directly in Aqueous Media for Environmental Applications	11
A Computational Approach for Respiratory Hazard Identification of Flavor Chemicals in Tobacco Products	11
Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Neuroblastoma Cells	11
High-Field Asymmetric Waveform Ion Mobility Spectrometry Analysis of Carcinogenic Aromatic Amines in Tobacco Smoke with an Orbitrap Tribrid Mass Spectrometer	11
Honoring Larry Marnett, Founding Editor of Chemical Research in Toxicology	11
Production of Peroxymonocarbonate by Steady-State Micromolar H2O2 and Activated Macrophages in the Presence of CO2/HCO3– Evidenced by Boronate Pr	11
Interview with Professor Cynthia J. Burrows, 2022 Founders Award Winner, American Chemical Society Division of Chemical Toxicology	11
8-Oxo-2′-deoxyguanosine Replication in Mutational Hot Spot Sequences of the p53 Gene in Human Cells Is Less Mutagenic than That of the Corresponding Formamidopyrimidine	11
Human Keratinocyte Responses to Woodsmoke Chemicals	11
Pyrroloquinoline Quinone Chemistry, Biology, and Biosynthesis	11
P38 MAPK, NF-κB, and JAK-STAT3 Signaling Pathways Involved in Capecitabine-Induced Hand-Foot Syndrome via Interleukin 6 or Interleukin 8 Abnormal Expression	11
Quantification of Intracellular DNA–Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity	10
Phthalate Exposure and Coronary Heart Disease: Possible Implications of Oxidative Stress and Altered miRNA Expression	10
Antioxidant Activity and Skin Sensitization of Eugenol and Isoeugenol: Two Sides of the Same Coin?	10

Human CYP2C19 Substrate and Inhibitor Characterization of Organophosphate Pesticides	10
Berberine Inhibits KLF4 Promoter Methylation and Ferroptosis to Ameliorate Diabetic Nephropathy in Mice	10
Effects of E-Cigarette Flavor Enhancing Capsules on Inhalable Aerosols	10
Ultrafast Reaction of the Drug Hydralazine with Apurinic/Apyrimidinic Sites in DNA Gives Rise to a Stable Triazolo[3,4-a]phthalazine Adduct	10
3-Ethenylpyridine Measured in Urine of Active and Passive Smokers: A Promising Biomarker and Toxicological Implications	10
Correction to “Oxymatrine Inhibits Liver Cancer Progression by Regulating SIRT1/YY1/GPX4 Axis-Mediated Ferroptosis”	10
Special Issue on Tobacco: Chemistry, Mechanisms, Biomarkers and Disease Prevention	10
Multiplatform Metabolomics to Understand the Imidacloprid-Induced Toxicity in Drosophila	10
Inhibitory Effects of Alkaloids on OATP1B1 In Vitro and In Vivo: Prediction for Food/Herb–Drug Interactions and Hepatoprotective Effects Based on Structure–Activity Relationships	10
New Insights into the Phototoxicity of Anthracene-Based Chromophores: The Chloride Salt Effect	10
Quantitation of Ten Urinary Nicotine Metabolites, Including 4-Hydroxy-4-(3-pyridyl) Butanoic Acid, a Product of Nicotine 2′-Oxidation, and CYP2A6 Activity in Japanese Americans, Native Hawaiians, and	10
Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins	10
A New Explanation for the Mystery of Rasputin’s Survival of Cyanide Poisoning: Eating Raw Garlic	10
Carbonyls and Aerosol Mass Generation from Vaping Nicotine Salt Solutions Using Fourth- and Third-Generation E-Cigarette Devices: Effects of Coil Resistance, Coil Age, and Coil Metal Material	10
Chlorobenzoquinones Aggravate RSL3-Induced Ferroptosis in ROS-Dependent Manner	10
The Dawn of a New Era in Drug Discovery? Drug Screening and the Increasing Biological Complexity of Testing Models	10
Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) in Wildtype, Cyp2abfgs-Null, and CYP2A6-Humanized Mice	9
Increased Levels of the Acrolein Metabolite 3-Hydroxypropyl Mercapturic Acid in the Urine of e-Cigarette Users	9
Evidence for the Metabolic Activation of Deferasirox In Vitro and In Vivo	9
Pesticides Inhibit Retinoic Acid Catabolism in PLHC-1 and ZFL Fish Hepatic Cell Lines	9
Chemical Exposures and Impact on Health	9
Is Baikiain in Tara Flour a Causative Agent for the Adverse Events Associated with the Recalled Frozen French Lentil & Leek Crumbles Food Product? - A Working Hypothesis	9
Searching for LINCS to Stress: Using Text Mining to Automate Reference Chemical Curation	9
Infection with Human Papillomavirus 18 Promotes Alkylating Agent-Induced Malignant Transformation in a Human Esophageal Cell Line	9
Issue Publication Information	9
In Vitro and In Vivo Studies of Metabolic Activation of Marrubiin, a Bioactive Constituent from Marrubium Vulgare	9
A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products	9
Identification of the Major Product of Guanine Oxidation in DNA by Ozone	9
Evaluation of Six Aromatic Amines in the Mainstream Smoke of Commercial Cigars	9
8-OxodGuo and Fapy•dG Mutagenicity in Escherichia coli Increases Significantly when They Are Part of a Tandem Lesion with 5-Formyl-2′-deoxyuridine	9
Polyamine Adducts with AP Sites: Interaction with DNA Polymerases and AP Endonucleases	9
Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation	9
Issue Publication Information	9
Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking	9
Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells	9
Inhibition of Nicotine Metabolism by Cannabidiol (CBD) and 7-Hydroxycannabidiol (7-OH-CBD)	9
In Vitro Evaluation of DNA Damage Effect Markers toward Five Nitrogen Mustards Based on Liquid Chromatography–Tandem Mass Spectrometry	9
Isotope Labeling Mass Spectrometry to Quantify Endogenous and Exogenous DNA Adducts and Metabolites of 1,3-Butadiene In Vivo	9
Issue Publication Information	8
Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity	8
Nature-Derived Epoxy Resin Monomers with Reduced Sensitizing Capacity─Isosorbide-Based Bis-Epoxides	8
Nuclear SUMOylation and Proteotoxic Stress Responses to Metals with Different Ligand Preferences	8
Metabolic Characterization of Sarin, Cyclosarin, and Novichoks (A-230, A-232) in Human Liver Microsomes	8
Oxidation of Naringenin, Apigenin, and Genistein by Human Family 1 Cytochrome P450 Enzymes and Comparison of Interaction of Apigenin with Human P450 1B1.1 and Scutellaria P450 82D.1	8
Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy	8
Mixtures-Inclusive In Silico Models of Ocular Toxicity Based on United States and International Hazard Categories	8
The Human Glyoxalase Gene Family in Health and Disease	8
Combining Molecular Docking and Pharmacophore Models Predicts Ligand Binding of Endocrine-Disrupting Chemicals to Nuclear Receptors	8
Assessment of the Exposure to Tobacco-Specific Nitrosamines and Minor Tobacco Alkaloids in Users of Various Tobacco/Nicotine Products	8
A Membrane Biophysics Perspective on the Mechanism of Alcohol Toxicity	8
Data Exploration for Target Predictions Using Proprietary and Publicly Available Data Sets	8
The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Comprehensive Review	8
Issue Editorial Masthead	8
Carbonyl Emissions and Heating Temperatures across 75 Nominally Identical Electronic Nicotine Delivery System Products: Do Manufacturing Variations Drive Pulmonary Toxicant Exposure?	8
Advances on the Influence of Methylmercury Exposure during Neurodevelopment	8
Natural Product Baohuoside I Impairs the Stability and Membrane Location of MRP2 Reciprocally Regulated by SUMOylation and Ubiquitination in Hepatocytes	8
MlrA, an Essential Enzyme for Microcystins and Nodularin on First Step Biodegradation in Microcystin-Degrading Bacteria	8
Improving Volatile Organic Compound Exposure Assessment Using Biomonitoring by Relating Exposure Biomarker Levels in Blood and Urine	8
Protease-Activated Receptor 2 (PAR-2) Antagonist AZ3451 Mitigates Oxidized Low-Density Lipoprotein (Ox-LDL)-Induced Damage and Endothelial Inflammation	8
Influence of Nitrite on Formation of Tobacco-Specific Nitrosamines in Electronic Cigarette Liquids and Aerosols	8
Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration	8
Quantification of Flavors, Volatile Organic Compounds, Tobacco Markers, and Tobacco-Specific Nitrosamines in Heated Tobacco Products and Their Mainstream Aerosol	8
Ratiometric Fluorescent Probe for the Detection of Nanomolar Phosgene in Solution and Gaseous Phase: Advancing Crime Detection Applications	8
Perfluorotridecanoic Acid Inhibits Leydig Cell Maturation in Male Rats in Late Puberty via Changing Testicular Lipid Component	8
Ambient Fine Particulate Matter and Cancer: Current Evidence and Future Perspectives	8
Using High-Throughput Screening to Evaluate Perturbations Potentially Linked to Neurobehavioral Outcomes: A Case Study Using Publicly Available Tools on FDA Batch-Certified Synthetic Food Dyes	7
Conformation and Pairing Properties of anO6-Methyl-2′-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA	7
The Potential Contribution of Hexavalent Chromium to the Carcinogenicity of Chrysotile Asbestos	7
In Vitro Metabolism and p53 Activation of Genotoxic Chemicals: Abiotic CYP Enzyme vs Liver Microsomes	7
Effect of Butyrate on Food-Grade Titanium Dioxide Toxicity in Different Intestinal In Vitro Models	7
Advances in Our Understanding of the Interaction of Drugs with T-cells: Implications for the Discovery of Biomarkers in Severe Cutaneous Drug Reactions	7
High-Throughput Screening of ToxCast PFAS Chemical Library for Potential Inhibitors of the Human Sodium Iodide Symporter	7
Identification of Specific Hemoglobin Adduct Patterns in Users of Different Tobacco/nicotine Products by Nontargeted GC–MS/MS Analysis	7
Network Pharmacology Combined with Metabolomics Approach to Investigate the Toxicity Mechanism of Paclobutrazol	7
Interview with Dr. Wei Yang, 2022 Keynote Speaker, American Chemical Society Division of Chemical Toxicology	7
Driving to a Better Understanding of Acyl Glucuronide Transformations Using NMR and Molecular Modeling	7
A Novel Inhibitor of Poly(ADP-Ribose) Polymerase-1 Inhibits Proliferation of a BRCA-Deficient Breast Cancer Cell Line via the DNA Damage–Activated cGAS–STING	7
In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells	7
Using Physical Organic Chemistry Knowledge to Predict Unusual Metabolites of Synthetic Phenolic Antioxidants by Cytochrome P450	7
Issue Publication Information	7
Polychlorinated Biphenyl Quinone Metabolites Cause Neutrophil Extracellular Traps in Mouse Bone Marrow Neutrophils	7
Characterization of Catecholaldehyde Adducts with Carnosine and l-Cysteine Reveals Their Potential as Biomarkers of Catecholaminergic Stress	7
A Virtual Issue of Chemical Research in Toxicology in Celebration of the International Day of Women and Girls in Science	7
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions	7
Issue Editorial Masthead	7
Urinary Profile of Alkylated DNA Adducts and DNA Oxidative Damage in Sulfur Mustard-Exposed Rats Revealed by Mass Spectrometry Quantification	7
Formation of DHP-DNA Adducts from Rat Liver Microsomal Metabolism of 1,2-Unsaturated Pyrrolizidine Alkaloid-Containing Plant Extracts and Dietary Supplements	7
Gerontology through the Eyes of 21st Century Toxicology	7
Formation of Redox-Active Duroquinone from Vaping of Vitamin E Acetate Contributes to Oxidative Lung Injury	7
Cytotoxic Homo- and Hetero-Dimers of o-toluidine, o-anisidine, and Aniline Formed by In Vitro Metabolism	7
Issue Editorial Masthead	7
A Quick Method for the Determination of the Fraction of Freebase Nicotine in Electronic Cigarettes	7
Quantum Chemical Evaluation and QSAR Modeling of N-Nitrosamine Carcinogenicity	7
MetSim: Integrated Programmatic Access and Pathway Management for Xenobiotic Metabolism Simulators	7
Dried Matrix Spots: An Underutilized and Unexplored Technology in India	7