OOIR: Observatory of International Research

Papers

(The H4-Index of Chemical Research in Toxicology is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology	168
Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes	144
Toxicity of Carbon Nanotubes: Molecular Mechanisms, Signaling Cascades, and Remedies in Biomedical Applications	75
Impact of e-Liquid Composition, Coil Temperature, and Puff Topography on the Aerosol Chemistry of Electronic Cigarettes	75
Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products	63
Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models	62
Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics	53
Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease	53
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities	50
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry	49
DeepDILI: Deep Learning-Powered Drug-Induced Liver Injury Prediction Using Model-Level Representation	48
Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies	48
Prediction of the Blood–Brain Barrier (BBB) Permeability of Chemicals Based on Machine-Learning and Ensemble Methods	47
Behavior Effects of Structurally Diverse Per- and Polyfluoroalkyl Substances in Zebrafish	44
Evaluating the Cytotoxicity of Ti₃C₂ MXene to Neural Stem Cells	42
Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes	41
Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing	40
Trade-off Predictivity and Explainability for Machine-Learning Powered Predictive Toxicology: An in-Depth Investigation with Tox21 Data Sets	40
Comparison of Cellular Morphological Descriptors and Molecular Fingerprints for the Prediction of Cytotoxicity- and Proliferation-Related Assays	38
Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies	37
Novel Δ⁸-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals	37
Toxicological Responses of α-Pinene-Derived Secondary Organic Aerosol and Its Molecular Tracers in Human Lung Cell Lines	34
Metabolism and Toxicity of Fluorine Compounds	33
What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure–Activity Relationships	32
Hormesis: A General Biological Principle	32

On Some Novel Similarity-Based Functions Used in the ML-Based q-RASAR Approach for Efficient Quantitative Predictions of Selected Toxicity End Points	32
Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed Caenorhabditis elegans	31
Machine Learning Models for Predicting Cytotoxicity of Nanomaterials	31
In Silico Models to Predict the Perturbation of Molecular Initiating Events Related to Thyroid Hormone Homeostasis	30
Cannabis Vaping: Existing and Emerging Modalities, Chemistry, and Pulmonary Toxicology	30