OOIR: Observatory of International Research

Papers

(The H4-Index of Chemical Research in Toxicology is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Issue Publication Information	89
Elevating Research and Careers in the Development of Safer Drugs through Artificial Intelligence	80
Identification of an Epoxide Metabolite of Amitriptyline In Vitro and In Vivo	76
Protein Haptenation and Its Role in Allergy	65
Issue Editorial Masthead	64
In Vitro and In Vivo Analysis of Fentanyl and Fentalog Metabolites using Hyphenated Chromatographic Techniques: A Review	61
Issue Editorial Masthead	61
Issue Publication Information	60
Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs	51
A Weakly Supervised Deep Learning Framework for Whole Slide Classification to Facilitate Digital Pathology in Animal Study	50
Coumarin-Based Noncytotoxicity Fluorescent Dye for Tracking Actin Protein in In-Vivo Imaging	46
Novel 4-Hydroxybenzyl Adducts in Human Hemoglobin: Structures and Mechanisms of Formation	45
Recent Advances in DNA Lesion Mapping and Repair Mechanisms	44
Capture of Electrophilic Quinones in the Extracellular Space: Evidence for a Phase Zero Reaction	44
Oxidative Deformylation of the Predominant DNA Lesion 5-Formyl-2′-deoxyuridine	42
Surfactant Coformulants in Glyphosate-Based Herbicides: Current Gaps, and Paths Forward in Human Biomonitoring	41
Advances in Metabolism and Metabolic Toxicology of Quinoxaline 1,4-Di-N-oxides	40
Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS)	40
Predicting Liver-Related In Vitro Endpoints with Machine Learning to Support Early Detection of Drug-Induced Liver Injury	36
Systematic Investigation of CYP3A4 Using Side-by-Side Comparisons of Apo, Active Site, and Allosteric-Bound States	34
Electrochemical Simulation of the Oxidative Capsaicin Metabolism	33
Issue Publication Information	33
Dissecting the Enantioselective Neurotoxicity of Isocarbophos: Chiral Insight from Cellular, Molecular, and Computational Investigations	33
Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells	32
Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy	31

A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies	31
Mechanistic Insights into Toxicity of Titanium Dioxide Nanoparticles at the Micro- and Macro-levels	31
LA-ICP-MS and Immunohistochemical Staining with Lanthanide-Labeled Antibodies to Study the Uptake of CeO₂ Nanoparticles by Macrophages in Tissue Sections	30
Direct Alkylation of Deoxyguanosine by Azaserine Leads to O⁶-Carboxymethyldeoxyguanosine	29