OOIR: Observatory of International Research

Papers

(The H4-Index of Chemical Research in Toxicology is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Elevating Research and Careers in the Development of Safer Drugs through Artificial Intelligence	147
Oxidative Deformylation of the Predominant DNA Lesion 5-Formyl-2′-deoxyuridine	143
Issue Publication Information	122
Issue Publication Information	109
Issue Editorial Masthead	83
Issue Editorial Masthead	80
Recent Advances in DNA Lesion Mapping and Repair Mechanisms	68
Identification of an Epoxide Metabolite of Amitriptyline In Vitro and In Vivo	66
Capture of Electrophilic Quinones in the Extracellular Space: Evidence for a Phase Zero Reaction	64
Surfactant Coformulants in Glyphosate-Based Herbicides: Current Gaps, and Paths Forward in Human Biomonitoring	61
Advances in Metabolism and Metabolic Toxicology of Quinoxaline 1,4-Di-N-oxides	58
Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs	57
Characterization of the Childhood Exposome with High-Resolution Mass Spectrometry	56
Dissecting the Enantioselective Neurotoxicity of Isocarbophos: Chiral Insight from Cellular, Molecular, and Computational Investigations	56
Coumarin-Based Noncytotoxicity Fluorescent Dye for Tracking Actin Protein in In-Vivo Imaging	54
Systematic Investigation of CYP3A4 Using Side-by-Side Comparisons of Apo, Active Site, and Allosteric-Bound States	51
Predicting Liver-Related In Vitro Endpoints with Machine Learning to Support Early Detection of Drug-Induced Liver Injury	48
Mechanistic Insights into Toxicity of Titanium Dioxide Nanoparticles at the Micro- and Macro-levels	44
Structure–Activity Relationship of Protein-Mediated Molecular Initiating Events of Organ-Specific Toxicities	44
Protein Haptenation and Its Role in Allergy	42
A Weakly Supervised Deep Learning Framework for Whole Slide Classification to Facilitate Digital Pathology in Animal Study	40
A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies	39
Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy	39
Issue Editorial Masthead	39
Issue Editorial Masthead	37

Issue Editorial Masthead	36
Issue Editorial Masthead	35
ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics	34
Mass Spectrometry-Based Metabolic Profiling of Urinary Metabolites of N′-Nitrosonornicotine (NNN) in the Rat	33
Photosensitized Oxidation of Free and Peptide Tryptophan to N-Formylkynurenine	32
Assessing the Toxicity of Terpene- and Amino Acid-Based Natural Deep Eutectic Solvents	31
Issue Publication Information	31
Predictive Modeling of DNA Damage Outcomes: Classification of Mutational Determinants Using Augmented Machine Learning Techniques	31
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models	31
Nonclinical Safety Signals in PharmaPendium Improve the Predictability of Human Drug-Induced Liver Injury	31