OOIR: Observatory of International Research

Papers

(The H4-Index of Chemical Research in Toxicology is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Clustering a Chemical Inventory for Safety Assessment of Fragrance Ingredients: Identifying Read-Across Analogs to Address Data Gaps	256
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology	142
Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes	116
Particulate Matter Toxicity Is Nrf2 and Mitochondria Dependent: The Roles of Metals and Polycyclic Aromatic Hydrocarbons	75
The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model	66
Neurotoxicology of Nanomaterials	62
Toxicity of Carbon Nanotubes: Molecular Mechanisms, Signaling Cascades, and Remedies in Biomedical Applications	58
Impact of e-Liquid Composition, Coil Temperature, and Puff Topography on the Aerosol Chemistry of Electronic Cigarettes	58
Review on Metal-Based Nanoparticles: Role of Reactive Oxygen Species in Renal Toxicity	55
GLORYx: Prediction of the Metabolites Resulting from Phase 1 and Phase 2 Biotransformations of Xenobiotics	51
Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products	51
Mitochondrial DNA Damage: Prevalence, Biological Consequence, and Emerging Pathways	47
Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models	46
Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies	42
Nuclear and Cytoplasmic Functions of Vitamin C	42
DeepDILI: Deep Learning-Powered Drug-Induced Liver Injury Prediction Using Model-Level Representation	41
Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics	40
Exposure to Aluminum, Cadmium, and Mercury and Autism Spectrum Disorder in Children: A Systematic Review and Meta-Analysis	38
In Vitro Toxicity and Chemical Characterization of Aerosol Derived from Electronic Cigarette Humectants Using a Newly Developed Exposure System	38
Crossing Biological Barriers by Engineered Nanoparticles	37
Evaluating the Cytotoxicity of Ti₃C₂ MXene to Neural Stem Cells	37
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities	36
Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease	36
A Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and Their Correlation with Oxidative Stress	35
Nanomaterials and Innate Immunity: A Perspective of the Current Status in Nanosafety	34

Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry	34
Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies	33
Prediction of the Blood–Brain Barrier (BBB) Permeability of Chemicals Based on Machine-Learning and Ensemble Methods	33
Therapeutic Potential of Carnosine and Its Derivatives in the Treatment of Human Diseases	33
Novel Δ⁸-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals	33
Impact of the Physicochemical Features of TiO₂ Nanoparticles on Their In Vitro Toxicity	33
Safety Assessment of Nanomaterials for Antimicrobial Applications	33
A Mechanical Mechanism for Vitamin E Acetate in E-cigarette/Vaping-Associated Lung Injury	32
Behavior Effects of Structurally Diverse Per- and Polyfluoroalkyl Substances in Zebrafish	32