Neuropsychopharmacology

Papers
(The TQCC of Neuropsychopharmacology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
A new prism next to motherhood’s light: uncovering changes in neural function following childbirth272
Using metabolic imaging to investigate neuromodulatory mechanisms of rTMS262
ACNP 62nd Annual Meeting: Keyword Index236
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation147
Pramipexole modulates fronto-subthalamic pathway in sequential working memory142
Potentiation of AMPA receptors for rapid therapeutic gain in psychiatry has reached a new level of excitement141
Delayed estrogen actions diminish food consumption without changing food approach, motor activity, or hypothalamic activation elicited by corticostriatal µ-opioid signaling124
ACNP 61st Annual Meeting: Poster Abstracts P541 – P809118
Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect116
Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation106
A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach94
Leveraging large-scale brain networks in rats to understand neurological and psychiatric disorders in humans89
Is treatment-resistant schizophrenia a neuroimmune condition? Meta-analytic evidence from magnetic resonance spectroscopy86
A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-naïve first episode schizophrenia: pharmacogenetic impact of86
Whole brain grey matter synaptic terminal density, age and intellectual functioning in schizophrenia: an in vivo [11C]UCB-J positron emission tomography study85
Infant sensory gating and a developmental cascade to autistic traits and anxiety80
Data-driven connectivity profiles relate to smoking cessation outcomes71
Distinct roles of excitatory and inhibitory neurons in the medial prefrontal cortex in the expression and reconsolidation of methamphetamine-associated memory in male mice70
Gestational ethanol exposure impairs motor skills in female mice through dysregulated striatal dopamine and acetylcholine function69
Motor signs in late life depression relate to altered subcortical synaptic density and gray matter volume: an 11C-UCB-J PET-MR study67
Inhibition of striatal indirect pathway during second postnatal week leads to long-lasting deficits in motivated behavior67
Prenatal serotonin reuptake inhibitor exposure and maternal depression symptoms are associated with altered fetal brain and placental development64
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study63
The sodium leak channel NALCN in Drd2+ striatal neurons regulates neuronal excitability, locomotion and food-seeking in a sex-dependent manner61
Acute fentanyl induces opposing directions of changes in tonic and phasic dopamine release patterns and impairs Pavlovian task performance60
Fueling the future: brain bioenergetics as a driver of neurodevelopment and mental health trajectories57
Leveraging ultra-high field (7T) MRI in psychiatric research55
Visual attention is linked to temporally structured noradrenaline release in the medial prefrontal cortex55
A sex-specific role for the bed nucleus of the stria terminalis in proactive defensive behavior54
Validation of a non-food or water motivated effort-based foraging task as a measure of motivational state in male mice53
Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse53
Contrasting roles of secondary motor cortex projections to the dorsolateral and dorsomedial striatum in incubation of cocaine-seeking50
TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner50
Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology49
Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis47
Epigenetic regulation of brain development, plasticity, and response to early-life stress46
Amplitude-determined seizure-threshold, electric field modeling, and electroconvulsive therapy antidepressant and cognitive outcomes45
Towards an understanding of psychedelic-induced neuroplasticity45
Parvalbumin interneuron mGlu5 receptors govern sex differences in prefrontal cortex physiology and binge drinking45
In Memoriam: Larry J. Young, PhD44
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios44
A covert cortical ensemble for learned fear suppression44
Indirect, but not direct, lateral habenula projections to ventral tegmental area regulate the long-term consequences of neuropathic pain44
Hedonic hotspot in rat olfactory tubercle: map for mu-opioid, orexin, and muscimol enhancement of sucrose ‘liking’43
Chronic, combinatorial targeting of NMDARs and 5-HT4Rs exerts extended behavioral effects against stress-induced perseverative behavior and hyponeophagia43
In Memoriam: Dr. James B. Appel43
Altered regulation of oligodendrocytes associated with parvalbumin neurons in the ventral hippocampus underlies fear generalization in male mice42
Namesake of PF-05231023: how nomenclature confusion leads to experimental misinterpretation in pharmacologic research42
Hypocretin receptor 1 blockade early in abstinence prevents incubation of cocaine seeking and normalizes dopamine transmission42
Model-based analysis of stop-signal data reveals robust neural and clinical correlates of evidence accumulation but not inhibition42
Hyper-maturity and accelerated aging in the hippocampus of mouse models of neuropsychiatric disorders with anxiety-like behavior41
NPP Editorial: tides of progress40
A path to novel, effective treatments for schizophrenia40
Development of a nose-poke restricted vaporized cocaine self-administration model in mice38
The hippocampus as a central hub in ketamine’s antidepressant action: from molecules to circuit rewiring38
Menstrual cycle and mental health in adolescents: a developmental neuroendocrine perspective38
Regulation of social hierarchy learning by serotonin transporter availability37
Digital frontlines: leveraging AI to augment human expertise in crisis and combat situations37
Consciousness, subjectivity, and aging in western thought36
Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice36
Psilocybin therapy for mood dysfunction in Parkinson’s disease: an open-label pilot trial35
Chronic treatment with fluoxetine regulates mitochondrial features and plasticity-associated transcriptomic pathways in parvalbumin-positive interneurons of prefrontal cortex35
Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity35
Effects of short-term quetiapine and lithium therapy for acute manic or mixed episodes on the limbic system and emotion regulation circuitry in youth with bipolar disorder35
Pharmacogenomic testing for antidepressant treatment selection: lessons learned and roadmap forward35
Network homeostasis: functional brain network alterations and relapse in remitted late-life depression34
Acute stress induces changes in epigenome-wide DNA methylation34
Persistent brain network signatures in psychosis: implications for diagnosis, prognosis, and treatment33
Synaptic effects of interleukin-6 on human iPSC-derived dopaminergic neurons33
Reporting checklists in neuroimaging: promoting transparency, replicability, and reproducibility33
NPP’s approach toward improving rigor and transparency in clinical trials research33
In Memoriam—Robert M. A. Hirschfeld, MD, MSc33
Dynamic and accessible pharmacogenomic results: a response to pharmacogenomic testing for antidepressant treatment selection32
Sex-specific and developmental effects of early life adversity on stress reactivity are rescued by postnatal knockdown of 5-HT1A autoreceptors32
The biological embedding of structural inequities: new insight from neuroscience32
Correction: Cue labeling reduces cigarette craving and associated neural activity32
Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia32
Evenamide reverses schizophrenia-related dysfunction in a neurodevelopmental animal model32
Individualized functional connectome identified generalizable biomarkers for psychiatric symptoms in transdiagnostic patients31
One step at a time: use of single-session rTMS to test novel targets for substance use disorders31
Pharmacokinetic-pharmacodynamic analysis of drug liking blockade by buprenorphine subcutaneous depot (CAM2038) in participants with opioid use disorder31
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial31
Modulation of methamphetamine memory reconsolidation by neural projection from basolateral amygdala to nucleus accumbens30
Cigarette smoking is associated with reduced neuroinflammation and better cognitive control in people living with HIV30
Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci30
Gamma-hydroxybutyrate to promote slow-wave sleep in major depressive disorder: a randomized crossover trial30
GluN2B inhibition confers resilience against long-term cocaine-induced neurocognitive sequelae29
For neuroscience, social history matters29
Retraction Note: Association between neuromelanin-sensitive MRI signal and psychomotor slowing in late-life depression29
Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3β and cyclic AMP signaling pathways28
Premature aging in serious mental illness28
Dorsal raphe nucleus enkephalin peptide modulates behavioral preference28
Precision functional mapping for target engagement in drug development28
Multiple sources of β2*-nicotinic acetylcholine receptor binding are differentially affected during tobacco smoking abstinence as revealed by Independent Component Analysis of [18F]Flubatine PET image27
A paraventricular thalamus to insular cortex glutamatergic projection gates “emotional” stress-induced binge eating in females27
M1 acetylcholine receptors in somatostatin interneurons contribute to GABAergic and glutamatergic plasticity in the mPFC and antidepressant-like responses27
nNOS-expressing neurons in the mPFC mediate depression-related behaviors in mice through pPVT-mPFC projections27
Neuroimaging education in psychiatric training27
Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction27
Acute dose-dependent effects and self-guided titration of continuous N,N-dimethyltryptamine infusions in a double-blind placebo-controlled study in healthy participants27
Methylphenidate undermines or enhances divergent creativity depending on baseline dopamine synthesis capacity27
CSF galanin and noradrenaline downregulation by psilocybin therapy in major depressive disorder27
Disinhibition of ventral tegmental area during initial punishment learning causes enduring punishment insensitivity26
Finding new and better treatments for psychiatric disorders26
Persistent vulnerability to heroin relapse after more than one year of abstinence in rats26
Longitudinal associations between white matter integrity, early life adversities, and treatment response following cognitive-behavioral therapy in depression25
Multisystem stress response biotypes: a precision psychiatry approach to identifying and treating multidimensional risk factors for anhedonia in adolescence25
Endocannabinoids at the synapse and beyond: implications for neuropsychiatric disease pathophysiology and treatment25
Prevention of late-life depression: a framework and prospectus for research24
Cracking the chicken and egg problem of schizophrenia and substance use: Genetic interplay between schizophrenia, cannabis use disorder, and tobacco smoking24
In Memoriam George K. Aghajanian, M.D. 1932 -202324
Clinical staging and profiling of affective disorders24
Reframing addiction: It’s not the destination, but the journey24
Neural basis of adolescent THC-induced potentiation of opioid responses later in life24
Central Executive Network drives delta-9-tetrahydrocannabinol (THC)-induced nonlinear changes in large-scale functional connectivity in adolescent nonhuman primates24
Genetic, environmental, and behavioral correlates of lifetime suicide attempt: Analysis of additive and interactive effects in two cohorts of US Army soldiers23
Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism23
Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder23
Formation and fate of an engram in the lateral amygdala supporting a rewarding memory in mice23
Sequence termination cues drive automated habit-like strategy via dopamine-mediated processes23
Serotonin type 3 receptor (5-HT3R) antagonists for negative symptoms and cognitive impairment associated with schizophrenia: a systematic review and meta-analysis23
Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[18F]flubatine PET study23
Mapping brain-wide activity networks: brainways as a tool for neurobiological discovery23
Cognition-enhancing and cognition-impairing doses of psychostimulants exert opposing actions on frontostriatal neural coding of delay in working memory23
Nucleus accumbens medial shell D1 and D2 medium spiny neurons signal the valence of conditioned stimuli in a sex-dependent manner23
Transdiagnostic subgroups of cognitive impairment in early affective and psychotic illness23
The role of subcortical brain tissue iron as an indicator of dopamine neurophysiology in adolescent cannabis use23
Identifying behavioral and biological predictors of cannabis vapor self-administration in rats23
Transcriptional profiles of antidepressant resistance across the corticolimbic pathway of chronically stressed mice22
Oxytocin effects on amygdala reactivity to angry faces in males and females with antisocial personality disorder22
Disrupted brain state dynamics in opioid and alcohol use disorder: attenuation by nicotine use22
N-acetylcysteine for youth cannabis use disorder: randomized controlled trial main findings22
Stress integration by an ascending adrenergic-melanocortin circuit22
Psychedelics produce enduring behavioral effects and functional plasticity through mechanisms independent of structural plasticity22
From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry22
UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice22
G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression22
The Tailtag: A multi-mouse tracking system to measure social dynamics in complex environments22
Investigating hierarchical critical periods in human neurodevelopment22
Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records22
Estrous cycle stage gates the effect of stress on reward learning21
Acute sleep disruption reduces fear memories in male and female mice21
Ensuring psychedelic treatments and research do not leave anyone behind21
Critical review and recommendations for enhancement of the article on novel neurosteroid therapeutics for postpartum depression21
Examining memory reconsolidation as a mechanism of nitrous oxide’s antidepressant action21
Ethical considerations in rapid and novel treatments in psychiatry21
In memoriam—Donald A. Overton, Ph.D21
Longevity, enhanced memory, and altered density of dendritic spines in hippocampal CA3 and dentate gyrus after hemizygous deletion of Pde2a in mice21
ACNP 63rd Annual Meeting: Poster Abstracts P305-P60821
Atypical cortical networks in children at high-genetic risk of psychiatric and neurodevelopmental disorders20
Correction: Punishment-resistant alcohol intake is mediated by the nucleus accumbens shell in female rats20
Correction: Neuroactive steroid biosynthesis during pregnancy predicts future postpartum depression: a role for the 3α and/or 3β-HSD neurosteroidogenic enzymes?20
Development of the McLean Hospital MENTOR Program to enhance mental health career pathways20
Correction: Neuropsychopharmacology Volume 50 Issue 120
The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats20
Moderators of treatment response in late-life depression19
Effects of lithium on aggression in Drosophila19
A ventral hippocampus to nucleus accumbens pathway regulates impulsivity in male but not female rats19
Quiet waves, deep impact: acoustic modeling of low-intensity focused ultrasound19
To dismantle structural racism in science, scientists need to learn how it works19
Using causal network mapping to clarify pre-clinical brain stimulation results19
Independent brain cortical signatures of risk for adolescent cannabis use and consequences of such use are moderated by sex19
Prefrontal corticotropin-releasing factor promotes resilience to social stress19
Rewired realities: novel insights into the neurobiology of cannabis use disorder and psychosis19
Phospholipase A2 downregulates inhibitory transmission in the amygdala and impairs fear extinction19
Inhibition of dorsal raphe GABAergic neurons blocks hyperalgesia during heroin withdrawal19
ACNP 62nd Annual Meeting: Poster Abstracts P1 – P25019
Considerations for conducting developmental neuroimaging research on mental health topics19
Selective orexin receptor cross-over treatment increases resilience and expression of neuroplastic signaling genes19
Abnormal ventromedial-to-dorsolateral hierarchical topography of striatal circuits in cocaine use disorder and its modulations by brain stimulation18
The future of brain circuit-targeted therapeutics18
Social isolation and aggression training lead to escalated aggression and hypothalamus-pituitary-gonad axis hyperfunction in mice18
Cannabidiol mitigates alcohol dependence and withdrawal with neuroprotective effects in the basolateral amygdala and striatum18
Greater subjective effects of a low dose of LSD in participants with depressed mood18
Disassociating drug active ingredients from inactive: ketamine-like synaptic effects of a ketamine excipient18
A pathway from the anterior cingulate cortex to the lateral habenula controls chronic pain-induced depression in male mice18
The association between cannabis use and brain reward anticipation: a 12-month longitudinal study of adults and adolescents who use cannabis and age-matched controls18
The positive allosteric modulator GNE-9278 increases gating, conductance, and Ca2+ permeability for GluN2D-containing NMDA receptors18
GABA release from central amygdala neurotensin neurons differentially modulates ethanol consumption in male and female mice18
Real-time fMRI neurofeedback: the promising potential of brain-training technology to advance clinical neuroscience18
The role of spousal relationships in shaping clinical trajectories during aging18
Demand for heroin in rats: effects of non-drug alternative substitutes and complements17
Identifying brain-penetrant small-molecule modulators of human microglia using a cellular model of synaptic pruning17
Genetic pleiotropy differentially linking brain variation to cannabis use and cannabis use disorder17
Control of dopamine communication by opioids: glutamate enters the discussion17
In Memoriam: Terry A. Ketter, MD17
Medial prefrontal cortex input to basolateral amygdala controls acute stress-induced short-term anxiety-like behavior in mice17
Refining the study of decision-making in animals: differential effects of d-amphetamine and haloperidol in a novel touchscreen-automated Rearing-Effort Discounting (RED) task and the Fixed-Ratio Effor17
The anxiogenic drug yohimbine is a reinforcer in male and female rats17
Elevated dorsal medial prefrontal cortex to lateral habenula pathway activity mediates chronic stress-induced depressive and anxiety-like behaviors17
Peptidomimetic inhibitors targeting TrkB/PSD-95 signaling improves cognition and seizure outcomes in an Angelman Syndrome mouse model17
Unexpected circuit-level tradeoffs in human stress resilience16
The impact of collider bias on genetic prediction in psychotic disorders16
Nucleus of the solitary tract A2 neurons control feeding behaviors via projections to the paraventricular hypothalamus16
Lasting effects of early-life oxytocin treatment on LTP and episodic memory in a mouse model of Fragile X syndrome16
Selective KOR antagonist alters functional patch sizes in individualized brain system: results from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS)16
Modulation of learning safety signals by acute stress: paraventricular thalamus and prefrontal inhibition16
A review of diffusion MRI in mood disorders: mechanisms and predictors of treatment response16
Robust aversive effects of trace amine-associated receptor 1 activation in mice16
Identifying novel proteins for suicide attempt by integrating proteomes from brain and blood with genome-wide association data16
Galanin receptor 1 expressing neurons in hippocampal-prefrontal circuitry modulate goal directed attention and impulse control16
Ro 64-6198, a selective NOP receptor agonist attenuates social impairments associated with NTG-induced migraine pain16
Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer’s disease15
Local and global effects of sedation in resting-state fMRI: a randomized, placebo-controlled comparison between etifoxine and alprazolam15
Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction15
In memoriam – George R. Breese, Ph.D15
Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants15
Sex-specific resting state brain network dynamics in patients with major depressive disorder15
Extended course accelerated intermittent theta burst stimulation as a substitute for depressed patients needing electroconvulsive therapy15
The promise of precision functional mapping for neuroimaging in psychiatry15
Concerted elevations of cortical and striatal glutamate and GABA in antipsychotic-free individuals at clinical high-risk for psychosis15
IN MEMORIAM Ghanshyam Narayan Pandey 1937–202215
ACNP 63rd Annual Meeting: Panels, Mini-Panels and Study Groups15
In memoriam – Ming T. Tsuang, M.D., Ph.D., D.Sc15
Neural underpinnings of open-label placebo effects in emotional distress15
Aversion-induced dopamine reductions predict drug-taking and escape behaviors15
Psilocybin improves novel object recognition in a rat model of Fragile X Syndrome through the modulation of the BDNF/TrkB signaling pathway15
Common side effects of MDMA-assisted psychotherapy15
Publisher Correction to: Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques15
Re-engineering the disordered mind: clinical experimentation, dynamical systems, and AI for personalized psychiatry15
Reliable variability in subjective responses to parenteral hydromorphone administration: empirical confirmation of an opioid non-responder phenotype14
A projection from the medial prefrontal cortex to the lateral septum modulates coping behavior on the shock-probe test14
Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area14
Retraction Note: Predator odor increases avoidance and glutamatergic synaptic transmission in the prelimbic cortex via corticotropin-releasing factor receptor 1 signaling14
Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter14
Pathways link environmental and genetic factors with structural brain networks and psychopathology in youth14
The effects of D-Cycloserine on corticospinal excitability after repeated spaced intermittent theta-burst transcranial magnetic stimulation: A randomized controlled trial in healthy individuals14
Testosterone eliminates strategic prosocial behavior through impacting choice consistency in healthy males14
Correction: Lateral habenula induces cognitive and affective dysfunctions in mice with neuropathic pain via an indirect pathway to the ventral tegmental area14
Random forest and Shapley Additive exPlanations predict oxytocin targeted effects on brain functional networks involved in salience and sensorimotor processing, in a randomized clinical trial in autis14
Is the stereoisomer R-MDMA a safer version of MDMA?14
Targeting depression circuitry with H1 coil Transcranial Magnetic Stimulation: a retrospective circuit mapping study14
Correction: Pharmacotherapy of major depressive disorder in older adults: from an evidence-informed stepwise algorithm to precision medicine14
Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine14
Change in brain molecular landscapes following electrical stimulation of the nucleus accumbens14
Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice14
To indulge or enrich: how environmental enrichment affects neurons that promote food seeking14
Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial14
Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala14
Beyond the hypothalamus: roles for insulin as a regulator of neurotransmission, motivation, and feeding14
Modulation of accumbens dopamine by MCH neurons during learning and consummatory behavior14
The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia14
Kappa opioid receptors as modulators of novelty processing13
Cocaine self-administration in adult female and male rhesus monkeys: longitudinal comparison with adolescent behavior and role of early life stress13
In memoriam: Kenneth E. Moore13
Childhood family environment and μ-opioid receptor availability in vivo in adulthood13
In Memoriam: Burton M. Angrist, MD13
Calcitonin receptor signal: a potential target for opioid use disorder?13
A large-scale c-Fos brain mapping study on extinction of cocaine-primed reinstatement13
ACNP 63rd Annual Meeting: Keyword Index13
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