Neuropsychopharmacology

Papers
(The median citation count of Neuropsychopharmacology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-08-01 to 2024-08-01.)
ArticleCitations
The role of prefrontal cortex in cognitive control and executive function447
Prefrontal cortex and depression242
The role of PFC networks in cognitive control and executive function215
Frequency and profile of objective cognitive deficits in hospitalized patients recovering from COVID-19149
Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial133
Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics128
Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects126
Addiction as a brain disease revised: why it still matters, and the need for consilience121
Development of prefrontal cortex120
Prefrontal cortex, amygdala, and threat processing: implications for PTSD113
All roads lead to the default-mode network—global source of DMN abnormalities in major depressive disorder109
Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia104
The prefrontal cortex, pathological anxiety, and anxiety disorders93
Neuromodulation of prefrontal cortex cognitive function in primates: the powerful roles of monoamines and acetylcholine91
Neurobiology of loneliness: a systematic review90
Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects87
Evolution of prefrontal cortex85
Sex differences in dopamine release regulation in the striatum84
Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau82
Towards an understanding of psychedelic-induced neuroplasticity81
Choosing appropriate language to reduce the stigma around mental illness and substance use disorders77
The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex71
Systematic misestimation of machine learning performance in neuroimaging studies of depression68
Left prefrontal transcranial magnetic stimulation for treatment-resistant depression in adolescents: a double-blind, randomized, sham-controlled trial63
Exploratory study of the dose-related safety, tolerability, and efficacy of dimethyltryptamine (DMT) in healthy volunteers and major depressive disorder62
Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation58
Reinforcement-learning in fronto-striatal circuits58
Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats56
Habit, choice, and addiction55
The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates53
The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study52
Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes52
The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward51
Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline46
Prefrontal connectomics: from anatomy to human imaging46
Differentiating the effect of antipsychotic medication and illness on brain volume reductions in first-episode psychosis: A Longitudinal, Randomised, Triple-blind, Placebo-controlled MRI Study45
Synaptic plasticity and mental health: methods, challenges and opportunities45
Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice45
Meta-analysis of human prediction error for incentives, perception, cognition, and action44
Common and specific large-scale brain changes in major depressive disorder, anxiety disorders, and chronic pain: a transdiagnostic multimodal meta-analysis of structural and functional MRI studies43
A versatile GPCR toolkit to track in vivo neuromodulation: not a one-size-fits-all sensor43
Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model43
Interactive relations between maternal prenatal stress, fetal brain connectivity, and gestational age at delivery43
Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-cente42
Alterations in microbiome composition and metabolic byproducts drive behavioral and transcriptional responses to morphine42
Release of endogenous dynorphin opioids in the prefrontal cortex disrupts cognition42
Efficacy and tolerability of baclofen in a U.S. community population with alcohol use disorder: a dose-response, randomized, controlled trial41
Covid-19 and promising solutions to combat symptoms of stress, anxiety and depression41
Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine40
Long-term safety and maintenance of response with esketamine nasal spray in participants with treatment-resistant depression: interim results of the SUSTAIN-3 study40
Telemedicine for treating mental health and substance use disorders: reflections since the pandemic40
Association of locus coeruleus integrity with Braak stage and neuropsychiatric symptom severity in Alzheimer’s disease40
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios39
Computational models of adaptive behavior and prefrontal cortex37
Accelerated brain aging predicts impulsivity and symptom severity in depression37
A potential biomarker for treatment stratification in psychosis: evaluation of an [18F] FDOPA PET imaging approach37
Differential and unique patterns of synaptic miRNA expression in dorsolateral prefrontal cortex of depressed subjects37
The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial37
Advances in modeling learning and decision-making in neuroscience36
The clinical effectiveness of using a predictive algorithm to guide antidepressant treatment in primary care (PReDicT): an open-label, randomised controlled trial35
Prognostic neuroimaging biomarkers of trauma-related psychopathology: resting-state fMRI shortly after trauma predicts future PTSD and depression symptoms in the AURORA study35
Real-time mobile monitoring of bipolar disorder: a review of evidence and future directions35
Functional connectivity during frustration: a preliminary study of predictive modeling of irritability in youth35
Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies35
Integration of brain and behavior measures for identification of data-driven groups cutting across children with ASD, ADHD, or OCD34
Astrocyte regulation of synaptic signaling in psychiatric disorders34
A meta-analysis of conditioned fear generalization in anxiety-related disorders33
Intrinsic connectivity of the prefrontal cortex and striato-limbic system respectively differentiate major depressive from generalized anxiety disorder33
The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity33
What’s wrong with my experiment?: The impact of hidden variables on neuropsychopharmacology research32
Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior32
The prefrontal cortex and OCD32
The role of anterior insula–brainstem projections and alpha-1 noradrenergic receptors for compulsion-like and alcohol-only drinking32
The renin–angiotensin system in PTSD: a replication and extension32
Sleep dysregulation in binge eating disorder and “food addiction”: the orexin (hypocretin) system as a potential neurobiological link31
Prefrontal cortex interactions with the amygdala in primates31
Somatostatin neurons control an alcohol binge drinking prelimbic microcircuit in mice31
The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial31
Co-released norepinephrine and galanin act on different timescales to promote stress-induced anxiety-like behavior31
A distributed frontotemporal network underlies gamma-band synchronization impairments in schizophrenia patients31
Efficacy and safety of transcranial direct current stimulation as an add-on treatment for obsessive-compulsive disorder: a randomized, sham-controlled trial30
Association of gray matter volumes with general and specific dimensions of psychopathology in children30
Rapid-acting antidepressants and the circadian clock30
Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning30
Optogenetic inhibition of indirect pathway neurons in the dorsomedial striatum reduces excessive grooming in Sapap3-knockout mice30
Neural circuits regulating prosocial behaviors30
Selective serotonin reuptake inhibitors and suicidal behaviour: a population-based cohort study30
Oxytocin receptor expression patterns in the human brain across development29
Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing29
Transgenerational modification of dopaminergic dysfunctions induced by maternal immune activation29
Regulation of risky decision making by gonadal hormones in males and females29
Associations among locus coeruleus catecholamines, tau pathology, and memory in aging29
The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain28
Autism risk gene KMT5B deficiency in prefrontal cortex induces synaptic dysfunction and social deficits via alterations of DNA repair and gene transcription28
Sustained effects of single doses of classical psychedelics in humans27
Interactions between ventrolateral prefrontal and anterior cingulate cortex during learning and behavioural change27
Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes27
White-matter free-water diffusion MRI in schizophrenia: a systematic review and meta-analysis27
Chronic social defeat stress impairs goal-directed behavior through dysregulation of ventral hippocampal activity in male mice27
Regulation of dopamine-dependent transcription and cocaine action by Gadd45b26
Dysregulation of threat neurocircuitry during fear extinction: the role of anhedonia26
Decreased striatal adenosine A2A-dopamine D2 receptor heteromerization in schizophrenia26
Dopamine transporter function fluctuates across sleep/wake state: potential impact for addiction26
Aberrant triple-network connectivity patterns discriminate biotypes of first-episode medication-naive schizophrenia in two large independent cohorts26
Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD25
The anterior retrosplenial cortex encodes event-related information and the posterior retrosplenial cortex encodes context-related information during memory formation25
Psilocybin for treatment resistant depression in patients taking a concomitant SSRI medication25
Dynamics of amygdala connectivity in bipolar disorders: a longitudinal study across mood states25
Dopamine D2 receptor signaling on iMSNs is required for initiation and vigor of learned actions25
Biotyping in psychosis: using multiple computational approaches with one data set25
Incerto-thalamic modulation of fear via GABA and dopamine25
MDMA-induced changes in within-network connectivity contradict the specificity of these alterations for the effects of serotonergic hallucinogens25
Enhanced heroin self-administration and distinct dopamine adaptations in female rats25
Remifentanil self-administration in mice promotes sex-specific prefrontal cortex dysfunction underlying deficits in cognitive flexibility25
Measuring maladaptive avoidance: from animal models to clinical anxiety25
Optogenetic stimulation of lateral hypothalamic orexin/dynorphin inputs in the ventral tegmental area potentiates mesolimbic dopamine neurotransmission and promotes reward-seeking behaviours25
Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients25
Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms24
Transcriptional signatures of the cortical morphometric similarity network gradient in first-episode, treatment-naive major depressive disorder24
Sex differences in appetitive and reactive aggression24
A robust and reproducible connectome fingerprint of ketamine is highly associated with the connectomic signature of antidepressants24
Complement component C4 levels in the cerebrospinal fluid and plasma of patients with schizophrenia24
Pituitary adenylate cyclase-activating polypeptide (PACAP) modulates dependence-induced alcohol drinking and anxiety-like behavior in male rats24
Neuroimaging correlates and predictors of response to repeated-dose intravenous ketamine in PTSD: preliminary evidence24
Beta-adrenergic blockade blunts inflammatory and antiviral/antibody gene expression responses to acute psychosocial stress24
Long-term alcohol consumption alters dorsal striatal dopamine release and regulation by D2 dopamine receptors in rhesus macaques24
Endogenous theta stimulation during meditation predicts reduced opioid dosing following treatment with Mindfulness-Oriented Recovery Enhancement24
Astrocyte-neuron signaling in the mesolimbic dopamine system: the hidden stars of dopamine signaling24
Applied natural language processing in mental health big data24
Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants23
Memantine effects on auditory discrimination and training in schizophrenia patients23
Insular cortex corticotropin-releasing factor integrates stress signaling with social affective behavior23
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders23
Telomere length and human hippocampal neurogenesis23
Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse23
Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications23
Patient-specific connectomic models correlate with, but do not reliably predict, outcomes in deep brain stimulation for obsessive-compulsive disorder23
Big data in psychiatry: multiomics, neuroimaging, computational modeling, and digital phenotyping22
Acute psilocybin enhances cognitive flexibility in rats22
Methylphenidate boosts choices of mental labor over leisure depending on striatal dopamine synthesis capacity22
Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study22
Beta-caryophyllene inhibits cocaine  addiction-related behavior by activation of PPARα and PPARγ: repurposing a FDA-approved food additive for cocaine use disorder22
Basal forebrain cholinergic signaling in the basolateral amygdala promotes strength and durability of fear memories22
Prefrontal contributions to the stability and variability of thought and conscious experience22
Genome-wide Mendelian randomization identifies actionable novel drug targets for psychiatric disorders22
Anterior cingulate cortex is necessary for spontaneous opioid withdrawal and withdrawal-induced hyperalgesia in male mice22
Adolescent stress sensitizes the adult neuroimmune transcriptome and leads to sex-specific microglial and behavioral phenotypes22
Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration21
Concordant neurophysiological signatures of cognitive control in humans and rats21
Are we compulsively chasing rainbows?21
A cross-species assay demonstrates that reward responsiveness is enduringly impacted by adverse, unpredictable early-life experiences21
Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants21
Within-subject, double-blinded, randomized, and placebo-controlled evaluation of the combined effects of the cannabinoid dronabinol and the opioid hydromorphone in a human laboratory pain model21
Genetic underpinnings of sociability in the general population21
GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia21
Rapid homeostatic plasticity and neuropsychiatric therapeutics21
Salivary beta-endorphin in nonsuicidal self-injury: an ambulatory assessment study21
Lower cholinergic basal forebrain volumes link with cognitive difficulties in schizophrenia21
Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity21
Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders20
Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats20
Distinct trajectories of response to prefrontal tDCS in major depression: results from a 3-arm randomized controlled trial20
Changes in the brain structural connectome after a prospective randomized clinical trial of lithium and quetiapine treatment in youth with bipolar disorder20
Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons20
Intrinsic reward circuit connectivity profiles underlying symptom and quality of life outcomes following antidepressant medication: a report from the iSPOT-D trial20
Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder20
Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase20
Effects of a psychedelic 5-HT2A receptor agonist on anxiety-related behavior and fear processing in mice20
Replicable association between human cytomegalovirus infection and reduced white matter fractional anisotropy in major depressive disorder20
Cocaine induces paradigm-specific changes to the transcriptome within the ventral tegmental area20
Cocaine and amphetamine regulated transcript (CART) signalling in the central nucleus of the amygdala modulates stress-induced alcohol seeking20
Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator19
Predicting change in diagnosis from major depression to bipolar disorder after antidepressant initiation19
Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats19
Change in prefrontal activity and executive functions after action-based cognitive remediation in bipolar disorder: a randomized controlled trial19
Adolescents are more sensitive than adults to acute behavioral and cognitive effects of THC19
Randomized controlled experimental study of hydrocortisone and D-cycloserine effects on fear extinction in PTSD19
Evaluating the evidence for sex differences: a scoping review of human neuroimaging in psychopharmacology research19
Klotho, PTSD, and advanced epigenetic age in cortical tissue19
Inactivation of the infralimbic cortex decreases discriminative stimulus-controlled relapse to cocaine seeking in rats19
The efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer’s disease: a randomized, triple-blind, placebo-controlled trial19
Orexin-1 receptor signaling in ventral tegmental area mediates cue-driven demand for cocaine19
Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa19
Traumatic memory reactivation with or without propranolol for PTSD and comorbid MD symptoms: a randomised clinical trial19
Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes19
Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry19
Larger dentate gyrus volume as predisposing resilience factor for the development of trauma-related symptoms19
Dynamic activity of interpeduncular nucleus GABAergic neurons controls expression of nicotine withdrawal in male mice18
Learning from lorcaserin: lessons from the negative clinical trial of lorcaserin to treat cocaine use disorder18
Epigenome-wide association study of alcohol use disorder in five brain regions18
Striatal Shati/Nat8l–BDNF pathways determine the sensitivity to social defeat stress in mice through epigenetic regulation18
Selective 5HT3 antagonists and sensory processing: a systematic review18
BDNF controls GABAAR trafficking and related cognitive processes via autophagic regulation of p6218
Behavioral and neurobiological effects of GnRH agonist treatment in mice—potential implications for puberty suppression in transgender individuals18
Metabolic adverse effects of off-label use of second-generation antipsychotics in the adult population: a systematic review and meta-analysis18
Nucleus accumbens dichotomically controls social dominance in male mice18
Behavioral and accumbens synaptic plasticity induced by cues associated with restraint stress18
Cognitive subtypes in recent onset psychosis: distinct neurobiological fingerprints?17
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP-36385617
Cell-type specific synaptic plasticity in dorsal striatum is associated with punishment-resistance compulsive-like cocaine self-administration in mice17
Rescue of histone hypoacetylation and social deficits by ketogenic diet in a Shank3 mouse model of autism17
Attention-deficit/hyperactivity disorder and the explore/exploit trade-off17
Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study17
Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime17
Increased functional coupling of the mu opioid receptor in the anterior insula of depressed individuals17
Long-term effects of intermittent early life stress on primate prefrontal–subcortical functional connectivity17
Transcriptome-wide association study of post-trauma symptom trajectories identified GRIN3B as a potential biomarker for PTSD development17
Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis17
Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer’s disease amyloidosis16
Symptomatic and neurotrophic effects of GABAA receptor positive allosteric modulation in a mouse model of chronic stress16
Distinct cortical thickness correlates of early life trauma exposure and posttraumatic stress disorder are shared among adolescent and adult females with interpersonal violence exposure16
Postpartum scarcity-adversity disrupts maternal behavior and induces a hypodopaminergic state in the rat dam and adult female offspring16
Reduced GABA/glutamate in the thalamus of individuals at clinical high risk for psychosis16
Association between polygenic risk for Alzheimer’s disease, brain structure and cognitive abilities in UK Biobank16
Do behavioral pharmacology findings predict clinical trial outcomes? A proof-of-concept in medication development for alcohol use disorder16
Astrocytes modulate extracellular neurotransmitter levels and excitatory neurotransmission in dorsolateral striatum via dopamine D2 receptor signaling16
Accelerated TMS - moving quickly into the future of depression treatment16
Ketamine in neuropsychiatric disorders: an update16
Sex differences in myelin content of white matter tracts in adolescents with depression16
Addiction should be treated, not penalized16
Modeling brain, symptom, and behavior in the winds of change16
Proof of concept study to develop a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment16
Early-life oxytocin attenuates the social deficits induced by caesarean-section delivery in the mouse16
5-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in mice16
The effect of lysergic acid diethylamide (LSD) on whole-brain functional and effective connectivity15
Minocycline differentially modulates human spatial memory systems15
A randomized double-blind, placebo-controlled pilot trial of mirtazapine for anxiety in children and adolescents with autism spectrum disorder15
The D-amino acid oxidase inhibitor luvadaxistat improves mismatch negativity in patients with schizophrenia in a randomized trial15
A randomized cross-over trial to define neurophysiological correlates of AV-101 N-methyl-d-aspartate receptor blockade in healthy veterans15
Modulation of arousal and sleep/wake architecture by M1 PAM VU0453595 across young and aged rodents and nonhuman primates15
Divergent modulation of pain and anxiety by GABAergic neurons in the ventrolateral periaqueductal gray and dorsal raphe15
The prefrontal cortex and (uniquely) human cooperation: a comparative perspective15
Rats choose alcohol over social reward in an operant choice procedure15
Transcriptomics in the nucleus accumbens shell reveal sex- and reinforcer-specific signatures associated with morphine and sucrose craving15
Quantitative standardization of resident mouse behavior for studies of aggression and social defeat15
Neural responses to reward anticipation and feedback in adult and adolescent cannabis users and controls15
Structure and function differences in the prelimbic cortex to basolateral amygdala circuit mediate trait vulnerability in a novel model of acute social defeat stress in male mice15
The role of orphan receptor GPR139 in neuropsychiatric behavior15
Dorsal striatal dopamine induces fronto-cortical hypoactivity and attenuates anxiety and compulsive behaviors in rats15
Novel neurosteroid therapeutics for post-partum depression: perspectives on clinical trials, program development, active research, and future directions15
Late-life depression accentuates cognitive weaknesses in older adults with small vessel disease14
Genome-wide meta-analysis of alcohol use disorder in East Asians14
Deconstructing dissociation: a triple network model of trauma-related dissociation and its subtypes14
RETRACTED ARTICLE: Association between neuromelanin-sensitive MRI signal and psychomotor slowing in late-life depression14
Association between age of cannabis initiation and gray matter covariance networks in recent onset psychosis14
Childhood maltreatment and cognitive functioning: the role of depression, parental education, and polygenic predisposition14
Adolescent social isolation induces distinct changes in the medial and lateral OFC-BLA synapse and social and emotional alterations in adult mice14
Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer’s disease14
Disentangling the roles of dopamine and noradrenaline in the exploration-exploitation tradeoff during human decision-making14
Rostral anterior cingulate network effective connectivity in depressed adolescents and associations with treatment response in a randomized controlled trial14
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