Immunopharmacology and Immunotoxicology

Papers
(The TQCC of Immunopharmacology and Immunotoxicology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
In vitro anti-tumor activities of a novel recombinant immunotoxin targeting differentially overexpressed Leucine-rich repeat-containing G-protein-coupled receptor 5 in cervical canc46
Assessing the effectiveness of camrelizumab plus anti-angiogenesis drug for the treatment of advanced liver cancer: a single‑center retrospective study31
Moscatilin protects concanavalin A-induced autoimmune liver disease in mice28
Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of27
Sirtinol, a SIRT1 inhibitor, inhibits the EMT and metastasis of 4T1 breast cancer cells and impacts the tumor microenvironment23
Leukoreduced PRP enhanced proliferation and ECM production yet inhibited senescence, inflammation, and multi-differentiation potential of AFSCs by downregulating HMGB123
Corynoline ameliorates dextran sulfate sodium-induced colitis in mice by modulating Nrf2/NF-κB pathway22
Beta-sitosterol alleviates inflammatory culprits and disease severity in arthritic irradiated rat’s model: role of brain-spleen axis22
Galantamine supplementation and rheumatoid arthritis: a systematic review of current research and molecular mechanisms22
Prospective therapeutic targets and recent advancements in the treatment of inflammatory bowel disease21
Inhibition of long-lived plasma cells, a critical role for Telitacicept treatment to systemic lupus erythematosus20
An overview of the current advances in the treatment of inflammatory diseases using mesenchymal stromal cell secretome20
Sevoflurane induces cognitive dysfunction by modulating PER2 methylation to block AKT pathway-suppressed NLRP3 inflammatory vesicle in microglia19
Withaferin A suppressed hepatocellular carcinoma progression through inducing IGF2BP3/FOXO1/JAK2/STAT3 pathway-mediated ROS production19
Neutrophil Extracellular Traps (NET) and SARS-CoV-218
Correction18
Monotropein alleviates acute pulmonary embolism in rats by inhibiting the NF-κB pathway18
Protective effect of pregabalin on renal and renal endothelial damage in sepsis induced by lipopolysaccharide17
Aryl-Cyclohexanone as a potential CB2 agonist: in vitro and in silico evidence in inflammatory modulation17
Role of oncostatin M and its receptor in the inflammatory pathogenesis of graves’ orbitopathy16
Sirt1/Nrf2/TNFα; TLR4/Myd88/NF-κB signaling pathways are involved in mediating hepatoprotective effect of bupropion in rat model of myocardial infarction16
Silver nanoparticle–conjugated pyrimidine-based BN6 methanimine derivative improves DSS-induced inflammatory bowel disease in zebrafish16
Systematic review of the efficacy and safety of lenvatinib in various solid tumors15
mTORC1 inhibition may improve T lymphocytes affected by aging15
Thymosin α1 improves the outcomes of patients with hepatitis B virus-related acute-on-chronic liver failure by restoring immune balance14
Dapagliflozin alleviates thioacetamide induced-liver fibrosis in rats via controlling the Nrf2/HO-1 and TLR4/TGF-β1/PI3K signaling pathways14
Correction14
Cancer-associated immune cells and their modulation by melatonin14
Losartan ameliorates premature ovarian failure by regulation of the Sirti1/NF-κB pathway in female albino rats14
Immunotherapeutic potentials of carnosol against lipopolysaccharides-induced acute inflammatory reactions in White Swiss albino mice14
SDH5 down-regulation mitigates the damage of osteoporosis via inhibiting the MyD88/NF-κB signaling pathway13
Celecoxib alleviates the DSS-induced ulcerative colitis in mice by enhancing intestinal barrier function, inhibiting ferroptosis and suppressing apoptosis13
Hydroxychloroquine ameliorates immune functionality and intestinal flora disorders of IgA nephropathy by inhibition of C1GALT1/Cosmc pathway13
Baicalin suppresses interleukin-1β-induced apoptosis, inflammatory response, oxidative stress, and extracellular matrix degradation in human nucleus pulposus cells12
CircRNA circ-PDCD11 is highly expressed in lung large-cell carcinoma and predicts poor survival12
Astragaloside IV restores Th17/Treg balance via inhibiting CXCR4 to improve chronic obstructive pulmonary disease11
Selective and effective suppression of pancreatic cancer through MNK inhibition11
Molecular mechanisms mediate roflumilast protective effect against isoprenaline-induced myocardial injury11
Clinical characteristics, treatment, and prognosis of ixekizumab-induced inflammatory bowel disease10
Association between serum baseline C1q and IgG levels and the efficacy of combined immunotherapy in patients with esophageal squamous cell carcinoma: a retrospective study10
Two flavonoids, baicalein and naringin, are effective as anti-inflammatory and anti-oxidant agents in a rat model of polymicrobial sepsis10
The effect of Vortioxetine on the NLRP3 pathway and microglial activity in the prefrontal cortex in an experimental model of depression10
Anticolitis effect of febuxostat. The imperative role of NLRP-3/Caspase-1/IL-1β pathway via histopathological, immunohistochemical and biochemical approach10
IGF2BP3 aggravates lung adenocarcinoma progression by modulation of PI3K/AKT signaling pathway9
T-cell metabolism in rheumatoid arthritis: focus on mitochondrial and lysosomal dysfunction9
Forkhead box A1 induces angiogenesis through activation of the S100A8/p38 MAPK axis in cutaneous wound healing9
Glucocorticoid receptor signaling: crosstalk with inflammation9
Cannabis sativa alleviates experimentally acetic acid- induced ulcerative colitis in rats: targeting CB1/SIRT/MAPK signaling pathways9
Gigantol protects retinal pigment epithelial cells against high glucose-induced apoptosis, oxidative stress and inflammation by inhibiting MTDH-mediated NF-kB signaling pathway9
Correction9
Role of EGF/ERK1/2/HO-1 axis in mediating methotrexate induced testicular damage in rats and the ameliorative effect of xanthine oxidase inhibitors8
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway8
Galectin-1-producing mesenchymal stem cells restrain the proliferation of T lymphocytes from patients with systemic lupus erythematosus8
Cardioprotective effect of tofisopam against isoprenaline-induced myocardial infarction in rats via modulation of NLRP3\IL-1β\caspase-1 pathway8
Luteolin restored Treg/Th17 balance to ameliorate allergic rhinitis in a mouse model8
Prognostic values of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in the early prediction of aluminum phosphide-poisoned patients’ outcomes8
Systemic administration of interleukin-10 is associated with dose-dependent toxicities in Wistar albino rats8
Seasonal facial erythema in a patient with allergic rhinitis treated using a combination of tranilast and roxithromycin8
Occupational exposure to pesticides affects systemic cytokine profile and correlates with poor clinical prognosis in young women with breast cancer8
Expression of calcitonin gene-related peptide in atopic dermatitis and correlation with distress7
Kindlin-2 silencing promoted apoptosis and cell cycle arrest through the fas/FasL pathway in hepatocellular carcinoma7
Evaluation of the inhibitory effect of different molecular weights chitosan on MRGPRX2-mediated mast cell degranulation and the pseudo-allergic reaction7
Rituximab beyond oncology: targeting B-cell-mediated immunomodulatory therapy in neurodegenerative and neuropsychiatric disorders7
Nanocarriers for lung health: ameliorating inflammation and cell aging using flavonoid-based nano nutrients7
Impact of glucocorticoids on interstitial lung disease: a medical information mart for intensive care and Mendelian randomization study7
Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer7
Impact of interleukin-32α on T helper cell-related cytokines, transcription factors, and proliferation in patients with type 2 diabetes mellitus7
Investigating the therapeutic efficacy of physical exercise on tumor immunity in a mouse model of malignant colon cancer7
Hydroxychloroquine exacerbates imiquimod-induced psoriasis-like dermatitis through stimulating overexpression of IL-6 in keratinocytes7
Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway7
Targeting alpha 7 nicotinic acetylcholine receptors by galantamine alleviates doxorubicin-induced cardiotoxicity via modulation of PI3K/AKT, Bax/Bcl-2, a7
Nodakenin attenuates cerebral ischemia–reperfusion injury by modulating the PI3K/AKT/NF-κB signaling pathway7
Time to treat the climate and nature crisis as one indivisible global health emergency7
Endoplasmic reticulum stress is upregulated in inflammatory bowel disease and contributed TLR2 pathway-mediated inflammatory response7
Efficacy and safety of the combined use of ipilimumab and nivolumab for melanoma patients with brain metastases: a systematic review and meta-analysis7
Therapeutic efficacy of tofacitinib in PDSAg-induced chronic experimental autoimmune uveitis in Wistar rat7
All- trans retinoic acid ameliorates S100-induced experimental autoimmune hepatitis by regulating the Treg/Th17 balance7
Safety assessment of voclosporin: a real-world disproportionality analysis of the FAERS database6
Vildagliptin attenuates doxorubicin-induced hepatotoxicity via activating Nrf2/HO-1 and SIRT1 and suppressing NF-κB signals in rats6
Febuxostat attenuates cyclophosphamide-induced ovarian toxicity; role of TLR4/NFκB/NLRP3 signaling pathway in female wistar albino rats6
The anti-inflammatory activity and toxicological safety of synthetic chalcone derivatives in preclinical trials6
The effect of vitamin C supplementation on favipiravir-induced oxidative stress and proinflammatory damage in livers and kidneys of rats6
The anti-inflammatory effects of vitamin B6 on neuroinflammation and neuronal damage caused by 1,2-diacetylbenzene in BV2 microglial and sH-SY5Y cells6
Fumaric acid per se and in combination with methotrexate arrests inflammation via moderating inflammatory and oxidative stress biomarkers in arthritic rats6
Investigation of the therapeutic potential of recombinant bispecific bivalent anti-PD-L1/VEGF nanobody in inhibition of angiogenesis6
Studying the effect of chronic toxicity of monosodium glutamate on interleukin-10 and interleukin-17 in albino Wistar rats6
Sodium benzoate exacerbates hepatic oxidative stress and inflammation in lipopolysaccharide-induced liver injury in rats6
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