OOIR: Observatory of International Research

Papers

(The median citation count of Autoimmunity is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Immunoenhancement activity of Bletilla striata polysaccharide through MAPK and NF-κB signalling pathways in vivo and in vitro	33
CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20	31
Knockdown of circ-PRKCH alleviates IL-1β-treated chondrocyte cell phenotypic changes through modulating miR-502-5p/ADAMTS5 axis	26
Circ_0110251 overexpression alleviates IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation by regulating miR-3189-3p/SPRY1 axis in osteoarthritis	25
Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes	20
Paeoniflorin improves autoimmune myocarditis in young rat by inhibiting CXCR5 to reduce follicular helper T cells	20
Sodium propionate improves rheumatoid arthritis by inhibiting survivin mediated proliferation of fibroblast like synoviocytes by promoting miR-140-5p	20
Circ-UQCRC2 aggravates lipopolysaccharide-induced injury in human bronchial epithelioid cells via targeting miR-495-3p/MYD88-mediated inflammatory response and oxidative stress	19
Abnormal lower expression of GPR183 in peripheral blood T and B cell subsets of systemic lupus erythematosus patients	18
LncRNA FOXD2-AS1 promotes cell proliferation and invasion of fibroblast-like synoviocytes by regulation of miR-331-3p/PIAS3 pathway in rheumatoid arthritis	17
The prevalence and role of functional autoantibodies to angiotensin-converting-enzyme-2 in patients with systemic sclerosis	17
Down-regulation of KLF9 ameliorates LPS-caused acute lung injury and inflammation in mice via reducing GSDMD expression	16
LncRNA CRNDE inhibits cardiomyocytes apoptosis by YAP1 in myocardial ischaemia/reperfusion injury	16
Deciphering distinct pathogenic mechanisms of ankylosing spondylitis and systemic sclerosis via shared biomarkers ZSWIM6 and CCL3L3: Insights from an integrative bioinformatics approach	16
LncRNA CALML3-AS1 regulates chondrocyte apoptosis by acting as a sponge for miR-146a	16
HERC6 is upregulated in peripheral blood mononuclear cells of patients with systemic lupus erythematosus and promotes the disease progression	15
MicroRNA-340-5p inhibits endothelial apoptosis, inflammatory response, and pro-coagulation by targeting KDM4C in anti-neutrophil cytoplasmic antibody (ANCA)-mediated glomerulonephritis through activat	15
HLA-transgenic mouse models to study autoimmune central nervous system diseases	14
IL-4 polymorphisms (rs2227284, rs2243267, and rs2243270) are associated with reduced risk of rheumatoid arthritis	14
Innovate therapeutic targets for autoimmune diseases: insights from proteome-wide mendelian randomization and Bayesian colocalization	14
Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway	13
Identification the role of necroptosis in rheumatoid arthritis by WGCNA network	13
Type B thymomas in patients with myasthenia gravis display a distinctive pattern of αβ TCR and IL-7 receptor α expression on CD4 ⁺ CD8 ⁺	13
Alteration of reactive oxygen species master transcription factor Nrf2 in keratinocytes exposed to monoclonal pathogenic antibody AK23 against desmoglein-3 in pemphigus vulgaris	13
CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1	13

The emerging role of the hedgehog signaling pathway in immunity response and autoimmune diseases	12
SARS-CoV-2 spike-specific regulatory T cells (Treg) expand and develop memory in vaccine recipients suggesting a role for immune regulation in preventing severe symptoms in COVID-19	12
Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis	12
Identification of prognostic biomarkers of breast cancer based on the immune-related gene module	11
DNA polymerase ζ suppresses the radiosensitivity of glioma cells by regulating the PI3K/AKT/mTOR pathway	11
Zinc finger protein 189 promotes the differentiation of lamina propria T helper 17.1 cells in dextran sulfate sodium-induced colitis	11
Effects of Apelin on the fibrosis of retinal tissues and Müller cells in diabetes retinopathy through the JAK2/STAT3 signalling pathway	10
Identification of a circRNA-miRNA-mRNA network to explore the effects of circRNAs on renal injury in systemic lupus erythematosus	10
Prognostic characteristics of T-cell mediated cell killing-related genes in lung adenocarcinoma	10
Circ_0006944 aggravates LPS-induced HK2 cell injury via modulating miR-205-5p/UBL4A pathway	10
KLF2 reduces dexamethasone-induced injury to growth plate chondrocytes by inhibiting the Runx2-mediated PI3K/AKT and ERK signalling pathways	10
The role of NLRP3 inflammasome in type 2 inflammation related diseases	9
BML-111 alleviates inflammatory response of alveolar epithelial cells via miR-494/Slit2/Robo4 signalling axis to improve acute lung injury	9
Berberine inhibits the development of endometrial cancer through circ_ZNF608/miR-377-3p/COX2 axis	9
Autoimmune inflammatory reactions triggered by the COVID-19 genetic vaccines in terminally differentiated tissues	9
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues	9
A novel circRNA, circRACGAP1, hampers the progression of systemic lupus erythematosus via miR-22-3p-mediated AKT signalling	9
LncRNA LINC00707 serves as a sponge of miR-382-5p to alleviate lipopolysaccharide (LPS)-induced WI-38 cell injury through upregulating NKAP in infantile pneumonia	9
Highly-expressed circ_0129657 inhibits proliferation as well as promotes apoptosis and inflammation in HBMECs after oxygen-glucose deprivation via miR-194-5p/GMFB axis	9
The onset of de novo autoantibodies in healthcare workers after mRNA based anti-SARS-CoV-2 vaccines: a single centre prospective follow-up study	9
Circ_0016347 modulates proliferation, migration, invasion, cell cycle, and apoptosis of osteosarcoma cells via the miR-661/IL6R axis	9
Knockdown of MKL1 ameliorates oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration by activating TWIST1-mediated PI3K/AKT signaling pathway in rats	9
LncRNA NEAT1 activates MyD88/NF-κB pathway in bronchopneumonia through targeting miR-155-5p	9
GADD45B predicts lung squamous cell carcinoma survival and impacts immune infiltration, and T cell exhaustion	9
Potential significance of changes in serum levels of IL-17, TNF-α and DKK-1 in the progression of the rheumatoid arthritis	9
The crosstalk between ferroptosis and autophagy in cancer	8
CircFLNA/miR-214 modulates regulatory T cells by regulating PD-1 in acute lung injury induced by sepsis	8
Circular RNA circZNF652 is overexpressed in osteoarthritis and positively regulates LPS-induced apoptosis of chondrocytes by upregulating PTEN	8
Characterization of IL-10-producing regulatory B cells in thymoma	8
COVID-19: captures iron and generates reactive oxygen species to damage the human immune system	8
The role of NLRP3 inflammasome in the pathogenesis of rheumatic disease	8
SLAMF8 promotes the proliferation and migration of synovial fibroblasts by regulating the ERK/MMPs signalling pathway	8
Contribution of DNA methylation to the pathogenesis of Sjögren's syndrome: A review	8
Systemic lupus erythematosus is associated with the risk of coeliac disease: a Mendelian randomisation study	8
Drug repurposing for rheumatoid arthritis: Identification of new drug candidates via bioinformatics and text mining analysis	8
Short interruptions of TNF-inhibitor treatment can be associated with treatment failure in patients with immune-mediated diseases	8
KISS-1 knockdown inhibits cell growth, migration, and invasion in HTR-8/SVneo cells by regulating the GRP54-mediated PI3K/AKT signaling pathway	7
Dysregulation of tumour microenvironment driven by circ-TPGS2/miR-7/TRAF6/NF-κB axis facilitates breast cancer cell motility	7
Mitochondria as a key player in systemic lupus erythematosus	7
FOXO3 as a potential diagnostic biomarker for autophagy in rheumatoid arthritis: A bioinformatics study	7
Increased IgD and CD27 Double Negative (DN) B cell population in pediatric onset autoimmune hepatitis	7
High throughput multiplex immunoassays stratify patients according to symptom burden across the anti-Ro positive systemic autoimmune rheumatic disease spectrum	7
LncRNA XIST is involved in rheumatoid arthritis fibroblast-like synoviocytes by sponging miR-126-3p via the NF-κB pathway	7
Astragaloside IV promotes the pyroptosis of airway smooth muscle cells in childhood asthma by suppressing HMGB1/RAGE axis to inactivate NF-κb pathway	7
Subchronic intranasal lipopolysaccharide exposure induces pulmonary autoimmunity and glomerulonephritis in NZBWF1 mice	7
Novel peripheral blood mononuclear cell mRNA signature for IFN-beta therapy responsiveness prediction in multiple sclerosis	7
MiR-146b-5p targets IFI35 to inhibit inflammatory response and apoptosis via JAK1/STAT1 signalling in lipopolysaccharide-induced glomerular cells	7
Circ_0036490 and DKK1 competitively bind miR-29a to promote lipopolysaccharides-induced human gingival fibroblasts injury	7
Effects of autoimmune abnormalities on fertility and placental morphology in mice	7
Progress in the field of animal models of antiphospholipid syndrome	6

PD-1 gene polymorphisms and thyroid expression of PD-1 ligands differ between Graves’ and Hashimoto’s diseases	6
MiR-361-5p promotes proliferation and inhibits apoptosis of fibroblast-like synoviocytes via targeting ZBTB10 in rheumatoid arthritis	6
MiR-144-3p induced by SP1 promotes IL-1β-induced pyroptosis in chondrocytes via PTEN/PINK1/Parkin axis	6
HSC70 is a novel binding partner involved in the capture of immunoglobulins on B cells in the NOD mouse	6
LncRNA ZNF667-AS1 alleviates rheumatoid arthritis by sponging miR-523-3p and inactivating the JAK/STAT signalling pathway	6
Partial long-term clinical improvement after a BCG challenge in systemic lupus erythematosus-prone mice	6
Aberrant microRNA expression in B lymphocytes from patients with primary warm autoimmune haemolytic anaemia	6
CircTRHDE knockdown protects WI-38 cells against LPS-induced inflammatory injury	6
Identified potential biomarkers may predict primary nonresponse to infliximab in patients with ulcerative colitis	6
IDO1-mediated M2 macrophage polarization alleviates the progression of ankylosing spondylitis	5
microRNA-130b-3p delivery by mesenchymal stem cells-derived exosomes confers protection on acute lung injury	5
LncRNA HOTAIR inhibits the progression of fibroblast-like synoviocytes by sponging miRNA-106b-5p in rheumatoid arthritis	5
Modulation of miR-382-5p reduces apoptosis of myocardial cells after acute myocardial infarction	5
TGFB1+869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus	5
Identification of TXN and F5 as novel diagnostic gene biomarkers of the severe asthma based on bioinformatics and machine learning analysis	5
Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study	5
Transient B-cell depletion and regulatory T-cells mediation in combination with adenovirus mediated IGF-1 prevents and reverses autoimmune diabetes in NOD mice	5
microRNA-17-5p downregulation inhibits autophagy and myocardial remodelling after myocardial infarction by targeting STAT3	5
Circ_0088036 facilitates the proliferation and inflammation and inhibits the apoptosis of fibroblast-like synoviocytes through targeting miR-326/FZD4 axis in rheumatoid arthritis	5
Circ_0114428 promotes proliferation, fibrosis and EMT process of high glucose-induced glomerular mesangial cells through regulating the miR-185-5p/SMAD3 axis	5
Identification of ANXA1 as a potential prognostic biomarker and correlating with immune infiltrates in colorectal cancer	5
LncRNA NORAD engages in psoriasis by binding to miR-26a to regulate keratinocyte proliferation	5
Correction	5
Identification of SAA1 as a prognostic biomarker associated with immune infiltration in glioblastoma	5
Exosomal miR-132-3p from mesenchymal stem cells alleviated LPS-induced acute lung injury by repressing TRAF6	5
SChLAP1 contributes to non-small cell lung cancer cell progression and immune evasion through regulating the AUF1/PD-L1 axis	5
MEOX2 serves as a novel biomarker associated with macrophage infiltration in oesophageal squamous cell carcinoma and other digestive system carcinomas	5
Circ_0005714/miR-223-3p/ADAM9 regulatory axis affects proliferation, migration, invasion, and angiopoiesis in trophoblast cells	5
Single-cell analysis with childhood and adult systemic lupus erythematosus	5
LncRNA DGCR5/miR-204-5p/SRSF7 axis regulates PDGF-BB-induced proliferation and migration of airway smooth muscle cells with potential role in asthma	4
OSR1 suppresses acute myeloid leukaemia cell proliferation by inhibiting LGR5-mediated JNK signalling	4
Dysregulated CXCL12 expression in osteoblasts promotes B-lymphocytes preferentially homing to the bone marrow in MRL/lpr mice	4
LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene	4
iTreg cells-secreted IL10 alleviates lupus nephritis through inactivating lncRNA HAR1A transcription to suppress SMARCD1-mediated iNOS activation	4
Hypoxic tumour-derived exosomal miR-1225-5p regulates M2 macrophage polarisation via toll-like receptor 2 to promote ovarian cancer progress	4
Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis	4
High-throughput autoantibody profiling of different stages of Schistosomiasis japonica	4
The lncRNA PVT1/miR-590-5p/FSTL1 axis modulates the proliferation and migration of airway smooth muscle cells in asthma	4
Sex-specific differences in SLE – Significance in the experimental setting of inflammation and kidney damage in MRL-Fas ^lpr mice	4
Bulk T-cell receptor sequencing confirms clonality in obstetric antiphospholipid syndrome and may as a potential biomarker	4
Progesterone decreased indoleamine 2,3-dioxygenase 1(IDO1) expression in early pregnancy chorionic villi and decidua	4
DNA methylation differences within INS , PTPN22 and IL2RA promoters in lymphocyte subsets in children with	4
Serum sirtuin-1 a potential marker in the diagnosis of rheumatoid arthritis	4
The utility of immunoglobulin A/complement 3 and immunoglobulin G/immunoglobulin M ratios in the assessment of disease activation in patients with Behçet disease	4
CD5L induces inflammation and survival in RA-FLS through ERK1/2 MAPK pathway	4
TMEM164 promotes ferroptosis by selectively mediating ATG5-dependent autophagosome formation to inhibit the progression of LUAD	4
Genome-wide identification of cell type-specific susceptibility genes for Juvenile dermatomyositis through the analysis of N ⁶ -methyladenosine-associated SNPs	4
Analysis of circulating immune cells in patients with rheumatoid arthritis and positive for hashimoto thyroiditis antibodies	4
Circ_0035796 depletion inhibits transforming growth factor-β1-induced pulmonary fibrosis in a miR-150-5p/L1CAM-dependent manner	4