Free Radical Biology and Medicine

Papers
(The TQCC of Free Radical Biology and Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury371
Ascorbic acid: The chemistry underlying its antioxidant properties281
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell280
Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy235
Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives214
Ubiquitin-specific protease 7 promotes ferroptosis via activation of the p53/TfR1 pathway in the rat hearts after ischemia/reperfusion169
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway136
Verification of ferroptosis and pyroptosis and identification of PTGS2 as the hub gene in human coronary artery atherosclerosis136
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling133
Senolytics and senomorphics: Natural and synthetic therapeutics in the treatment of aging and chronic diseases129
Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells122
Exosomes from adipose-derived stem cells alleviate the inflammation and oxidative stress via regulating Nrf2/HO-1 axis in macrophages121
Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs–NF–κB signaling pathway and pyroptosis after secondary spinal cord injury115
Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4112
AGE/RAGE in diabetic kidney disease and ageing kidney110
Targeting SLC3A2 subunit of system XC− is essential for m6A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma109
The emerging potential of cold atmospheric plasma in skin biology109
Green tea derivative (−)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo106
Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis105
Hypoxia inhibits RANKL-induced ferritinophagy and protects osteoclasts from ferroptosis105
Nrf2 for protection against oxidant generation and mitochondrial damage in cardiac injury103
The role of glutathione redox imbalance in autism spectrum disorder: A review102
Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse98
The role of glutathione peroxidase-1 in health and disease95
Reactivity and degradation products of tryptophan in solution and proteins94
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy94
Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury93
Browsing the oldest antioxidant enzyme: catalase and its multiple regulation in cancer92
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects91
Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage90
The glutathione peroxidase family: Discoveries and mechanism88
The role of NO in COVID-19 and potential therapeutic strategies85
Regulation of Nrf2 by phosphorylation: Consequences for biological function and therapeutic implications85
Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis85
Transcription factor NRF2 as a promising therapeutic target for Alzheimer’s disease82
Altered glucose metabolism in Alzheimer's disease: Role of mitochondrial dysfunction and oxidative stress79
DNA damage and oxidant stress activate p53 through differential upstream signaling pathways78
Glycyrrhetinic acid induces oxidative/nitrative stress and drives ferroptosis through activating NADPH oxidases and iNOS, and depriving glutathione in triple-negative breast cancer cells78
Oxidative stress in cardiac hypertrophy: From molecular mechanisms to novel therapeutic targets78
Mitochondrial dysfunction promotes aquaporin expression that controls hydrogen peroxide permeability and ferroptosis76
Spermidine endows macrophages anti-inflammatory properties by inducing mitochondrial superoxide-dependent AMPK activation, Hif-1α upregulation and autophagy75
The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease75
Molecular mechanisms underlying health benefits of tea compounds74
Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress73
NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2/Gpx4 pathway73
Mitochondrial unfolded protein response: An emerging pathway in human diseases73
Vitamin E alpha- and gamma-tocopherol mitigate colitis, protect intestinal barrier function and modulate the gut microbiota in mice72
mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder72
Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis71
The dark side of gamma-glutamyltransferase (GGT): Pathogenic effects of an ‘antioxidant’ enzyme71
PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation69
Bufotalin induces ferroptosis in non-small cell lung cancer cells by facilitating the ubiquitination and degradation of GPX469
Beneficial effects of dietary supplementation with olive oil, oleic acid, or hydroxytyrosol in metabolic syndrome: Systematic review and meta-analysis69
Irisin protects against sepsis-associated encephalopathy by suppressing ferroptosis via activation of the Nrf2/GPX4 signal axis69
Mitochondrial ROS and mitochondria-targeted antioxidants in the aged heart68
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes68
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury66
Nrf2 as a regulator of mitochondrial function: Energy metabolism and beyond65
Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/HIF-1α s63
AMP-activated protein kinase: A remarkable contributor to preserve a healthy heart against ROS injury63
Wedelolactone alleviates acute pancreatitis and associated lung injury via GPX4 mediated suppression of pyroptosis and ferroptosis63
Oxidative stress and regeneration61
Upregulation of oxidative stress gene markers during SARS-COV-2 viral infection60
Vitamin E as an essential micronutrient for human health: Common, novel, and unexplored dietary sources59
Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway59
m6A methylation is required for dihydroartemisinin to alleviate liver fibrosis by inducing ferroptosis in hepatic stellate cells58
The homeostatic role of hydrogen peroxide, superoxide anion and nitric oxide in the vasculature58
MitoQ alleviates LPS-mediated acute lung injury through regulating Nrf2/Drp1 pathway58
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway57
Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway56
Angelica dahurica promoted angiogenesis and accelerated wound healing in db/db mice via the HIF-1α/PDGF-β signaling pathway56
Quercetin alleviates kainic acid-induced seizure by inhibiting the Nrf2-mediated ferroptosis pathway56
Tannic acid, a promising anti-photoaging agent: Evidences of its antioxidant and anti-wrinkle potentials, and its ability to prevent photodamage and MMP-1 expression in L929 fibroblasts exposed to UVB56
Iron homeostasis and disorders revisited in the sepsis56
Pharmacological inhibition of MELK restricts ferroptosis and the inflammatory response in colitis and colitis-propelled carcinogenesis56
Mitoquinone attenuates vascular calcification by suppressing oxidative stress and reducing apoptosis of vascular smooth muscle cells via the Keap1/Nrf2 pathway55
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion55
Redox signaling pathways in unilateral ureteral obstruction (UUO)-induced renal fibrosis55
Natural and synthetic antioxidants targeting cardiac oxidative stress and redox signaling in cardiometabolic diseases55
Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management54
The potential link between inherited G6PD deficiency, oxidative stress, and vitamin D deficiency and the racial inequities in mortality associated with COVID-1954
Catalase: A critical node in the regulation of cell fate54
Atorvastatin alleviates microglia-mediated neuroinflammation via modulating the microbial composition and the intestinal barrier function in ischemic stroke mice54
Vitexin alleviates high-fat diet induced brain oxidative stress and inflammation via anti-oxidant, anti-inflammatory and gut microbiota modulating properties54
Discovery of new therapeutic redox targets for cardioprotection against ischemia/reperfusion injury and heart failure53
Nrf2 knockout altered brain iron deposition and mitigated age-related motor dysfunction in aging mice52
Adipose tissue macrophage-derived exosomes induce ferroptosis via glutathione synthesis inhibition by targeting SLC7A11 in obesity-induced cardiac injury52
Melatonin alleviates heat stress-induced oxidative stress and apoptosis in human spermatozoa52
Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration51
Lipid oxidation that is, and is not, inhibited by vitamin E: Consideration about physiological functions of vitamin E51
TIGAR drives colorectal cancer ferroptosis resistance through ROS/AMPK/SCD1 pathway51
AMPK and NRF2: Interactive players in the same team for cellular homeostasis?49
Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation49
Cyanidin-3-O-β-glucoside inactivates NLRP3 inflammasome and alleviates alcoholic steatohepatitis via SirT1/NF-κB signaling pathway48
The calcium–iron connection in ferroptosis-mediated neuronal death48
Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate experimental non-alcoholic steatohepatitis via Nrf2/NQO-1 pathway47
JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy47
Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics47
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 346
Reflections of an aging free radical46
Aging lens epithelium is susceptible to ferroptosis46
Vitamin E: How much is enough, too much and why!45
Primary Coenzyme Q deficiencies: A literature review and online platform of clinical features to uncover genotype-phenotype correlations45
The role of ceramide accumulation in human induced pluripotent stem cell-derived cardiomyocytes on mitochondrial oxidative stress and mitophagy45
Vitamin E research: Past, now and future45
Heme oxygenase-1(HO-1) regulates Golgi stress and attenuates endotoxin-induced acute lung injury through hypoxia inducible factor-1α (HIF-1α)/HO-1 signaling pathway45
Neuroinflammation-mediated mitochondrial dysregulation involved in postoperative cognitive dysfunction44
STAT3-mediated ferroptosis is involved in ulcerative colitis44
Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway44
Selenoprotein P – Selenium transport protein, enzyme and biomarker of selenium status44
Rehmapicroside ameliorates cerebral ischemia-reperfusion injury via attenuating peroxynitrite-mediated mitophagy activation43
Manganese induces tumor cell ferroptosis through type-I IFN dependent inhibition of mitochondrial dihydroorotate dehydrogenase42
Heme oxygenase-1 modulation: A potential therapeutic target for COVID-19 and associated complications42
Mediterranean diet and cognitive function: From methodology to mechanisms of action42
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling42
Conductivity augments ROS and RNS delivery and tumor toxicity of an argon plasma jet42
Age-dependent accumulation of dicarbonyls and advanced glycation endproducts (AGEs) associates with mitochondrial stress41
Downregulation of dihydrolipoyl dehydrogenase by UVA suppresses melanoma progression via triggering oxidative stress and altering energy metabolism41
ACSL4 and the lipoxygenases 15/15B are pivotal for ferroptosis induced by iron and PUFA dyshomeostasis in dopaminergic neurons41
Susceptibility of the patients infected with Sars-Cov2 to oxidative stress and possible interplay with severity of the disease41
Interventional study with vitamin E in cardiovascular disease and meta-analysis41
Mitochondria signaling to the epigenome: A novel role for an old organelle41
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy40
NFκB promotes oxidative stress-induced necrosis and ischemia/reperfusion injury by inhibiting Nrf2-ARE pathway39
Novel perspectives on redox signaling in red blood cells and platelets in cardiovascular disease39
Azocompounds as generators of defined radical species: Contributions and challenges for free radical research39
A novel function of ATF3 in suppression of ferroptosis in mouse heart suffered ischemia/reperfusion39
Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway39
Tumor cell metabolism correlates with resistance to gas plasma treatment: The evaluation of three dogmas39
Baicalein limits osteoarthritis development by inhibiting chondrocyte ferroptosis39
Role of Nrf2 dysfunction in the pathogenesis of diabetic nephropathy: Therapeutic prospect of epigallocatechin-3-gallate39
Metabolism of natural forms of vitamin E and biological actions of vitamin E metabolites39
Dioscin ameliorates methotrexate-induced liver and kidney damages via adjusting miRNA-145-5p-mediated oxidative stress38
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer38
Deiodinases control local cellular and systemic thyroid hormone availability38
Chronic intermittent hypoxia-induced mitochondrial dysfunction mediates endothelial injury via the TXNIP/NLRP3/IL-1β signaling pathway38
Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation37
Curcumin–cyclodextrin/cellulose nanocrystals improve the phenotype of Charcot-Marie-Tooth-1A transgenic rats through the reduction of oxidative stress37
H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis37
Vitamin D deficiency exacerbates Alzheimer-like pathologies by reducing antioxidant capacity37
NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway37
Mitochondrial redox and TCA cycle metabolite signaling in the heart36
The decrease of selenoprotein K induced by selenium deficiency in diet improves apoptosis and cell progression block in chicken liver via the PTEN/PI3K/AKT pathway36
NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model36
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling36
Regulation of Nrf2 signaling pathway in heart failure: Role of extracellular vesicles and non-coding RNAs36
Flavonoid 4,4′-dimethoxychalcone induced ferroptosis in cancer cells by synergistically activating Keap1/Nrf2/HMOX1 pathway and inhibiting FECH36
One-carbon epigenetics and redox biology of neurodegeneration35
Protective role of hydrogen sulfide against diabetic cardiomyopathy via alleviating necroptosis35
Oxidative stress-mediated alterations in histone post-translational modifications35
Low shear stress induced vascular endothelial cell pyroptosis by TET2/SDHB/ROS pathway35
A white paper on Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) forty years later35
Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The HORTEGA study35
Cadmium-induced oxidative stress responses and acclimation in plants require fine-tuning of redox biology at subcellular level35
Activation of MAT2A-ACSL3 pathway protects cells from ferroptosis in gastric cancer35
Sources and triggers of oxidative damage in neurodegeneration35
Ferrostatin-1 obviates seizures and associated cognitive deficits in ferric chloride-induced posttraumatic epilepsy via suppressing ferroptosis35
Oxidative stress induces downregulation of TP53INP2 and suppresses osteogenic differentiation of BMSCs during osteoporosis through the autophagy degradation pathway35
Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair35
Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency34
Therapeutic effects of non-saponin fraction with rich polysaccharide from Korean red ginseng on aging and Alzheimer's disease34
miR-15a-5p inhibits metastasis and lipid metabolism by suppressing histone acetylation in lung cancer34
Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia34
The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function34
Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries34
Lipid metabolism and oxidative stress in HPV-related cancers34
Canonical Wnt signaling works downstream of iron overload to prevent ferroptosis from damaging osteoblast differentiation34
Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors34
Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice34
TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway33
Plasma GSH levels and Alzheimer's disease. A prospective approach.: Results from the HELIAD study33
Epigenetic activation of RBM15 promotes clear cell renal cell carcinoma growth, metastasis and macrophage infiltration by regulating the m6A modification of CXCL1133
Nrf2 contributes to the benefits of exercise interventions on age-related skeletal muscle disorder via regulating Drp1 stability and mitochondrial fission33
The gut microbiota metabolite glycochenodeoxycholate activates TFR-ACSL4-mediated ferroptosis to promote the development of environmental toxin–linked MAFLD33
ROS and redox regulation of cell-to-cell and systemic signaling in plants during stress33
Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation33
Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling33
Compartmentally scavenging hepatic oxidants through AMPK/SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism33
STING-dependent induction of lipid peroxidation mediates intestinal ischemia-reperfusion injury33
Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy32
Antioxidant function of phytocannabinoids: Molecular basis of their stability and cytoprotective properties under UV-irradiation32
The intestinal 3M (microbiota, metabolism, metabolome) zeitgeist – from fundamentals to future challenges32
Sirtuin 3: Emerging therapeutic target for cardiovascular diseases32
The molecular and physiological consequences of cold plasma treatment in murine skin and its barrier function32
Myricetin prevents high molecular weight Aβ1-42 oligomer-induced neurotoxicity through antioxidant effects in cell membranes and mitochondria32
Enhanced alleviation of insulin resistance via the IRS-1/Akt/FOXO1 pathway by combining quercetin and EGCG and involving miR-27a-3p and miR-96–5p32
Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy32
PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression32
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome31
Redox signaling in heart failure and therapeutic implications31
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling31
Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice31
Melatonin inhibits the apoptosis of rooster Leydig cells by suppressing oxidative stress via AKT-Nrf2 pathway activation31
Programmed cell death factor 4 (PDCD4), a novel therapy target for metabolic diseases besides cancer31
Host/microbiota interactions-derived tryptophan metabolites modulate oxidative stress and inflammation via aryl hydrocarbon receptor signaling31
High-fat diet aggravates colitis-associated carcinogenesis by evading ferroptosis in the ER stress-mediated pathway31
High glucose-induced PRDX3 acetylation contributes to glucotoxicity in pancreatic β-cells: Prevention by Teneligliptin31
Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes31
α-Tocopherol transfer protein (α-TTP)31
Redox modulation by plant polyphenols targeting vitagenes for chemoprevention and therapy: Relevance to novel anti-cancer interventions and mini-brain organoid technology31
Antioxidant activity of highly hydroxylated fullerene C60 and its interactions with the analogue of α-tocopherol31
Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma31
Decreased expression of IDH1 by chronic unpredictable stress suppresses proliferation and accelerates senescence of granulosa cells through ROS activated MAPK signaling pathways31
Functional segmentation of CoQ and cyt c pools by respiratory complex superassembly30
Suppressing long noncoding RNA OGRU ameliorates diabetic retinopathy by inhibition of oxidative stress and inflammation via miR-320/USP14 axis30
The alarmone (p)ppGpp confers tolerance to oxidative stress during the stationary phase by maintenance of redox and iron homeostasis in Staphylococcus aureus30
Hinokitiol functions as a ferroptosis inhibitor to confer neuroprotection30
Inflammation-dependent oxidative stress metabolites as a hallmark of amyotrophic lateral sclerosis30
The multiple roles of coenzyme Q in cellular homeostasis and their relevance for the pathogenesis of coenzyme Q deficiency29
Hydroxysafflor yellow A and anhydrosafflor yellow B alleviate ferroptosis and parthanatos in PC12 cells injured by OGD/R29
The multimodal action of genistein in Alzheimer's and other age-related diseases29
VDR activation attenuates osteoblastic ferroptosis and senescence by stimulating the Nrf2/GPX4 pathway in age-related osteoporosis29
Anti-ageing effects of ubiquinone and ubiquinol in a senescence model of human dermal fibroblasts29
Nanodelivery of natural isothiocyanates as a cancer therapeutic29
Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf229
Rosmarinic acid prevents refractory bacterial pneumonia through regulating Keap1/Nrf2-mediated autophagic pathway and mitochondrial oxidative stress29
Oxidative stress-induced aberrant lipid metabolism is an important causal factor for dysfunction of immunocytes from patients with systemic lupus erythematosus29
Resistance to artemisinin in falciparum malaria parasites: A redox-mediated phenomenon29
Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F1629
Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols29
Overlooked and valuable facts to know in the NRF2/KEAP1 field28
Selenoprotein V protects against endoplasmic reticulum stress and oxidative injury induced by pro-oxidants28
Reflections on a century of vitamin E research: Looking at the past with an eye on the future28
Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain of rats28
Hydroxytyrosol prevents periodontitis-induced bone loss by regulating mitochondrial function and mitogen-activated protein kinase signaling of bone cells28
ER stress—induced adipocytes secrete-aldo-keto reductase 1B7—containing exosomes that cause nonalcoholic steatohepatitis in mice28
Adrenaline induces calcium signal in astrocytes and vasoconstriction via activation of monoamine oxidase28
Polymorphisms in genes related to oxidative stress and inflammation: Emerging links with the pathogenesis and severity of Cerebral Cavernous Malformation disease28
Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury28
Thioredoxin reductase 1 inhibitor shikonin promotes cell necroptosis via SecTRAPs generation and oxygen-coupled redox cycling28
Elevated branched-chain α-keto acids exacerbate macrophage oxidative stress and chronic inflammatory damage in type 2 diabetes mellitus28
Timosaponin BII improved osteoporosis caused by hyperglycemia through promoting autophagy of osteoblasts via suppressing the mTOR/NFκB signaling pathway27
Gamma irradiation promotes chemo-sensitization potential of gallic acid through attenuation of autophagic flux to trigger apoptosis in an NRF2 inactivation signalling pathway27
Dehydroepiandrosterone alleviates intestinal inflammatory damage via GPR30-mediated Nrf2 activation and NLRP3 inflammasome inhibition in colitis mice27
Functional role of the SLC7A11-AS1/xCT axis in the development of gastric cancer cisplatin-resistance by a GSH-dependent mechanism27
Coenzyme Q redox signalling and longevity27
The role of vitamin C in epigenetic cancer therapy27
Nicotinamide riboside promotes Mfn2-mediated mitochondrial fusion in diabetic hearts through the SIRT1-PGC1α-PPARα pathway27
Vanadium pentoxide nanoparticle mediated perturbations in cellular redox balance and the paradigm of autophagy to apoptosis27
Physical plasma-derived oxidants sensitize pancreatic cancer cells to ferroptotic cell death27
Sirt3 deficiency accelerates ovarian senescence without affecting spermatogenesis in aging mice27
The use of glutathione to reduce oxidative stress status and its potential for modifying the extracellular matrix organization in cleft lip27
Evaluating the bactericidal action of hypochlorous acid in culture media27
Reactive Oxygen Species in intestinal stem cell metabolism, fate and function27
Genetic elucidation of hydrogen signaling in plant osmotic tolerance and stomatal closure via hydrogen sulfide27
Disrupting CISD2 function in cancer cells primarily impacts mitochondrial labile iron levels and triggers TXNIP expression27
Nicotinamide mononucleotide inhibits hepatic stellate cell activation to prevent liver fibrosis via promoting PGE2 degradation26
Reported evidence of vitamin E protection against cataract and glaucoma26
Itaconate regulates the glycolysis/pentose phosphate pathway transition to maintain boar sperm linear motility by regulating redox homeostasis26
Necroptosis triggered by ROS accumulation and Ca2+ overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivo26
0.024487972259521