Free Radical Biology and Medicine

Article	Citations
Lipid peroxidation and ferroptosis: The role of GSH and GPx4	701
Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease	548
Air pollution and its effects on the immune system	315
Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury	292
Ascorbic acid: The chemistry underlying its antioxidant properties	219
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell	216
Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy	180
Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives	147
Ubiquitin-specific protease 7 promotes ferroptosis via activation of the p53/TfR1 pathway in the rat hearts after ischemia/reperfusion	141
Beyond repression of Nrf2: An update on Keap1	140
Resveratrol reduces obesity in high-fat diet-fed mice via modulating the composition and metabolic function of the gut microbiota	131
Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections	126
Oxidative stress and the cardiovascular effects of air pollution	123
Verification of ferroptosis and pyroptosis and identification of PTGS2 as the hub gene in human coronary artery atherosclerosis	109
Potential benefits and risks of omega-3 fatty acids supplementation to patients with COVID-19	108
Ferroptosis was more initial in cell death caused by iron overload and its underlying mechanism in Parkinson's disease	103
Senolytics and senomorphics: Natural and synthetic therapeutics in the treatment of aging and chronic diseases	96
Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells	95
The emerging potential of cold atmospheric plasma in skin biology	94
Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs–NF–κB signaling pathway and pyroptosis after secondary spinal cord injury	94
Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4	93
Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies	93
Exosomes from adipose-derived stem cells alleviate the inflammation and oxidative stress via regulating Nrf2/HO-1 axis in macrophages	91
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway	91
Ambient particulate matter oxidative potential: Chemical determinants, associated health effects, and strategies for risk management	88

Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling	88
AGE/RAGE in diabetic kidney disease and ageing kidney	86
Green tea derivative (−)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo	86
The role of glutathione redox imbalance in autism spectrum disorder: A review	84
Targeting SLC3A2 subunit of system XC− is essential for m6A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma	84
Hypoxia inhibits RANKL-induced ferritinophagy and protects osteoclasts from ferroptosis	81
The role of NO in COVID-19 and potential therapeutic strategies	80
Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse	79
Urolithin A-induced mitophagy suppresses apoptosis and attenuates intervertebral disc degeneration via the AMPK signaling pathway	76
Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis	74
Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury	74
Regulation of Nrf2 by phosphorylation: Consequences for biological function and therapeutic implications	72
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects	72
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy	72
Browsing the oldest antioxidant enzyme: catalase and its multiple regulation in cancer	70
Cold plasma seed priming modulates growth, redox homeostasis and stress response by inducing reactive species in tomato (Solanum lycopersicum)	70
Reactivity and degradation products of tryptophan in solution and proteins	69
Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage	69
Nrf2 for protection against oxidant generation and mitochondrial damage in cardiac injury	67
Transcription factor NRF2 as a promising therapeutic target for Alzheimer’s disease	67
Butyrate alleviates oxidative stress by regulating NRF2 nuclear accumulation and H3K9/14 acetylation via GPR109A in bovine mammary epithelial cells and mammary glands	67
Nitrate ameliorates dextran sodium sulfate-induced colitis by regulating the homeostasis of the intestinal microbiota	65
The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases	65
PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation	64
Mitochondrial dysfunction promotes aquaporin expression that controls hydrogen peroxide permeability and ferroptosis	62
Impact of air pollution on intestinal redox lipidome and microbiome	62
Molecular mechanisms underlying health benefits of tea compounds	61
Spermidine endows macrophages anti-inflammatory properties by inducing mitochondrial superoxide-dependent AMPK activation, Hif-1α upregulation and autophagy	61
The glutathione peroxidase family: Discoveries and mechanism	61
Glycyrrhetinic acid induces oxidative/nitrative stress and drives ferroptosis through activating NADPH oxidases and iNOS, and depriving glutathione in triple-negative breast cancer cells	61
Drp1-regulated PARK2-dependent mitophagy protects against renal fibrosis in unilateral ureteral obstruction	61
Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress	60
Oxidative stress in cardiac hypertrophy: From molecular mechanisms to novel therapeutic targets	59
Beneficial effects of dietary supplementation with olive oil, oleic acid, or hydroxytyrosol in metabolic syndrome: Systematic review and meta-analysis	59
Vitamin E alpha- and gamma-tocopherol mitigate colitis, protect intestinal barrier function and modulate the gut microbiota in mice	58
Mitochondrial unfolded protein response: An emerging pathway in human diseases	57
The role of glutathione peroxidase-1 in health and disease	57
The dark side of gamma-glutamyltransferase (GGT): Pathogenic effects of an ‘antioxidant’ enzyme	56
Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/HIF-1α s	56
Disulfiram suppresses NLRP3 inflammasome activation to treat peritoneal and gouty inflammation	56
mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder	55
Anthocyanins reduce inflammation and improve glucose and lipid metabolism associated with inhibiting nuclear factor-kappaB activation and increasing PPAR-γ gene expression in metabolic syndrome subjec	54
Relevance of Nrf2 and heme oxygenase-1 in articular diseases	54
Upregulation of oxidative stress gene markers during SARS-COV-2 viral infection	53
The potential link between inherited G6PD deficiency, oxidative stress, and vitamin D deficiency and the racial inequities in mortality associated with COVID-19	53
Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease	53
The homeostatic role of hydrogen peroxide, superoxide anion and nitric oxide in the vasculature	53
Frailty as a phenotypic manifestation of underlying oxidative stress	53
DNA damage and oxidant stress activate p53 through differential upstream signaling pathways	52
Mitochondrial ROS and mitochondria-targeted antioxidants in the aged heart	52

Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis	51
Wedelolactone alleviates acute pancreatitis and associated lung injury via GPX4 mediated suppression of pyroptosis and ferroptosis	51
Increasing ovarian NAD+ levels improve mitochondrial functions and reverse ovarian aging	51
AMP-activated protein kinase: A remarkable contributor to preserve a healthy heart against ROS injury	50
Camellia oil alleviates the progression of Alzheimer's disease in aluminum chloride-treated rats	50
Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway	50
Oxidative stress in air pollution research	50
Redox signaling pathways in unilateral ureteral obstruction (UUO)-induced renal fibrosis	50
The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease	49
Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis	49
Oxidative stress and exceptional human longevity: Systematic review	48
microRNA-181 serves as a dual-role regulator in the development of human cancers	47
Mitoquinone attenuates vascular calcification by suppressing oxidative stress and reducing apoptosis of vascular smooth muscle cells via the Keap1/Nrf2 pathway	47
Natural and synthetic antioxidants targeting cardiac oxidative stress and redox signaling in cardiometabolic diseases	47
MitoQ alleviates LPS-mediated acute lung injury through regulating Nrf2/Drp1 pathway	46
Role of reactive oxygen species in atherosclerosis: Lessons from murine genetic models	46
Altered glucose metabolism in Alzheimer's disease: Role of mitochondrial dysfunction and oxidative stress	45
Aerobic exercise alleviates oxidative stress-induced apoptosis in kidneys of myocardial infarction mice by inhibiting ALCAT1 and activating FNDC5/Irisin signaling pathway	45
Discovery of new therapeutic redox targets for cardioprotection against ischemia/reperfusion injury and heart failure	45
Tannic acid, a promising anti-photoaging agent: Evidences of its antioxidant and anti-wrinkle potentials, and its ability to prevent photodamage and MMP-1 expression in L929 fibroblasts exposed to UVB	45
Oxidative stress and regeneration	45
Geniposide protects against sepsis-induced myocardial dysfunction through AMPKα-dependent pathway	45
NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2/Gpx4 pathway	45
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway	45
Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management	44
The role of Nrf2 in acute kidney injury: Novel molecular mechanisms and therapeutic approaches	44
Bufotalin induces ferroptosis in non-small cell lung cancer cells by facilitating the ubiquitination and degradation of GPX4	44
Nrf2 knockout altered brain iron deposition and mitigated age-related motor dysfunction in aging mice	44
Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer	44
The circular RNA TLK1 exacerbates myocardial ischemia/reperfusion injury via targeting miR-214/RIPK1 through TNF signaling pathway	44
Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration	43
Pharmacological inhibition of MELK restricts ferroptosis and the inflammatory response in colitis and colitis-propelled carcinogenesis	43
Angelica dahurica promoted angiogenesis and accelerated wound healing in db/db mice via the HIF-1α/PDGF-β signaling pathway	43
Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice	43
Vitexin alleviates high-fat diet induced brain oxidative stress and inflammation via anti-oxidant, anti-inflammatory and gut microbiota modulating properties	43
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury	43
Reflections of an aging free radical	42
Heme oxygenase-1 modulation: A potential therapeutic target for COVID-19 and associated complications	41
How the redox state regulates immunity	40
TIGAR drives colorectal cancer ferroptosis resistance through ROS/AMPK/SCD1 pathway	40
Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics	39
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion	39
The role of ceramide accumulation in human induced pluripotent stem cell-derived cardiomyocytes on mitochondrial oxidative stress and mitophagy	39
Atorvastatin alleviates microglia-mediated neuroinflammation via modulating the microbial composition and the intestinal barrier function in ischemic stroke mice	39
Vitamin E as an essential micronutrient for human health: Common, novel, and unexplored dietary sources	39
Heme Oxygenase-1 in liver transplant ischemia-reperfusion injury: From bench-to-bedside	39
Role of Nrf2 in MALAT1/ HIF-1α loop on the regulation of angiogenesis in diabetic foot ulcer	38
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes	38
Melatonin alleviates heat stress-induced oxidative stress and apoptosis in human spermatozoa	38
Chronic impairment of mitochondrial bioenergetics and β-oxidation promotes experimental AKI-to-CKD transition induced by folic acid	38
Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes	38
Quercetin alleviates kainic acid-induced seizure by inhibiting the Nrf2-mediated ferroptosis pathway	38
Irisin protects against sepsis-associated encephalopathy by suppressing ferroptosis via activation of the Nrf2/GPX4 signal axis	38
Cyanidin-3-O-β-glucoside inactivates NLRP3 inflammasome and alleviates alcoholic steatohepatitis via SirT1/NF-κB signaling pathway	38
Natural ingredients-derived antioxidants attenuate H2O2-induced oxidative stress and have chondroprotective effects on human osteoarthritic chondrocytes via Keap1/Nrf2 pathway	37
Oxidative contribution of air pollution to extrinsic skin ageing	37
Indoleamine 2, 3-dioxygenase 1enhanceshepatocytes ferroptosis in acute immune hepatitis associated with excess nitrative stress	37
Iron homeostasis and disorders revisited in the sepsis	37
The role of NADPH oxidases in neuronal development	37
Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation	37
Lipid oxidation that is, and is not, inhibited by vitamin E: Consideration about physiological functions of vitamin E	37
Astrocyte hepcidin ameliorates neuronal loss through attenuating brain iron deposition and oxidative stress in APP/PS1 mice	36
Susceptibility of the patients infected with Sars-Cov2 to oxidative stress and possible interplay with severity of the disease	36
Heme oxygenase-1(HO-1) regulates Golgi stress and attenuates endotoxin-induced acute lung injury through hypoxia inducible factor-1α (HIF-1α)/HO-1 signaling pathway	35
Ailanthone increases oxidative stress in CDDP-resistant ovarian and bladder cancer cells by inhibiting of Nrf2 and YAP expression through a post-translational mechanism	35
Mediterranean diet and cognitive function: From methodology to mechanisms of action	35
Vitamin E: How much is enough, too much and why!	35
m6A methylation is required for dihydroartemisinin to alleviate liver fibrosis by inducing ferroptosis in hepatic stellate cells	35
Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway	35
Acetyl-11-keto-β-boswellic acid ameliorates cognitive deficits and reduces amyloid-β levels in APPswe/PS1dE9 mice through antioxidant and anti-inflammatory pathways	35
Adipose tissue macrophage-derived exosomes induce ferroptosis via glutathione synthesis inhibition by targeting SLC7A11 in obesity-induced cardiac injury	35
Novel perspectives on redox signaling in red blood cells and platelets in cardiovascular disease	35
Azocompounds as generators of defined radical species: Contributions and challenges for free radical research	34
Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The HORTEGA study	34
The antioxidant activity and neuroprotective mechanism of isoliquiritigenin	34
The calcium–iron connection in ferroptosis-mediated neuronal death	34
Conductivity augments ROS and RNS delivery and tumor toxicity of an argon plasma jet	34
Hepatocyte-specific deficiency of Nrf2 exacerbates carbon tetrachloride-induced liver fibrosis via aggravated hepatocyte injury and subsequent inflammatory and fibrogenic responses	34
Multiple functions of 2-Cys peroxiredoxins, I and II, and their regulations via post-translational modifications	34
Primary Coenzyme Q deficiencies: A literature review and online platform of clinical features to uncover genotype-phenotype correlations	34

Curcumin–cyclodextrin/cellulose nanocrystals improve the phenotype of Charcot-Marie-Tooth-1A transgenic rats through the reduction of oxidative stress	34
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3	33
Crosstalk between oxidative stress-induced apoptotic and autophagic signaling pathways in Zn(II) phthalocyanine photodynamic therapy of melanoma	33
The decrease of selenoprotein K induced by selenium deficiency in diet improves apoptosis and cell progression block in chicken liver via the PTEN/PI3K/AKT pathway	33
Tumor cell metabolism correlates with resistance to gas plasma treatment: The evaluation of three dogmas	33
Nrf2 as a regulator of mitochondrial function: Energy metabolism and beyond	33
Rehmapicroside ameliorates cerebral ischemia-reperfusion injury via attenuating peroxynitrite-mediated mitophagy activation	33
Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols	32
Vitamin D deficiency exacerbates Alzheimer-like pathologies by reducing antioxidant capacity	32
Oxidative stress-mediated alterations in histone post-translational modifications	32
Mitochondria signaling to the epigenome: A novel role for an old organelle	32
The effect of oxidative and reductive stress on semen parameters and functions of physiologically normal human spermatozoa	32
Redox regulation of cutaneous inflammasome by ozone exposure	32
Age-dependent accumulation of dicarbonyls and advanced glycation endproducts (AGEs) associates with mitochondrial stress	32
Downregulation of dihydrolipoyl dehydrogenase by UVA suppresses melanoma progression via triggering oxidative stress and altering energy metabolism	32
Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway	32
A white paper on Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) forty years later	32
Mitochondrial superoxide/hydrogen peroxide: An emerging therapeutic target for metabolic diseases	32
NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model	32
Role of Nrf2 dysfunction in the pathogenesis of diabetic nephropathy: Therapeutic prospect of epigallocatechin-3-gallate	32
Chronic intermittent hypoxia-induced mitochondrial dysfunction mediates endothelial injury via the TXNIP/NLRP3/IL-1β signaling pathway	31
Low shear stress induced vascular endothelial cell pyroptosis by TET2/SDHB/ROS pathway	31
Dioscin ameliorates methotrexate-induced liver and kidney damages via adjusting miRNA-145-5p-mediated oxidative stress	31
MicroRNA-based regulatory mechanisms underlying the synergistic antioxidant action of quercetin and catechin in H2O2-stimulated HepG2 cells: Roles of BACH1 in Nrf2-dependent pathways	31
NFκB promotes oxidative stress-induced necrosis and ischemia/reperfusion injury by inhibiting Nrf2-ARE pathway	31
STING-dependent induction of lipid peroxidation mediates intestinal ischemia-reperfusion injury	31
Aging lens epithelium is susceptible to ferroptosis	31
CYP11A1-derived vitamin D3 products protect against UVB-induced inflammation and promote keratinocytes differentiation	31
Vitamin E research: Past, now and future	31
One-carbon epigenetics and redox biology of neurodegeneration	30
Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia	30
miR-15a-5p inhibits metastasis and lipid metabolism by suppressing histone acetylation in lung cancer	30
Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling	30
Ellagic acid protects Caco-2 cell monolayers against inflammation-induced permeabilization	30
A novel function of ATF3 in suppression of ferroptosis in mouse heart suffered ischemia/reperfusion	30
Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2	29
Mitochondrial DNA, oxidants, and innate immunity	29
Neuroinflammation-mediated mitochondrial dysregulation involved in postoperative cognitive dysfunction	29
Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes	29
Regulation of Nrf2 signaling pathway in heart failure: Role of extracellular vesicles and non-coding RNAs	29
Plasma GSH levels and Alzheimer's disease. A prospective approach.: Results from the HELIAD study	29
H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis	29
NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway	29
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer	29
AMPK and NRF2: Interactive players in the same team for cellular homeostasis?	29
Interventional study with vitamin E in cardiovascular disease and meta-analysis	29
Extracellular vesicles and redox modulation in aging	29
Therapeutic effects of non-saponin fraction with rich polysaccharide from Korean red ginseng on aging and Alzheimer's disease	28
Mitochondrial redox and TCA cycle metabolite signaling in the heart	28
Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma	28
PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression	28
Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors	28
Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling	28
Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair	28
Sanguinarine as a new chemical entity of thioredoxin reductase inhibitor to elicit oxidative stress and promote tumor cell apoptosis	28
Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries	28
Increased mitochondrial content and function by resveratrol and select flavonoids protects against benzo[a]pyrene-induced bioenergetic dysfunction and ROS generation in a cell model of neoplastic tran	28
Antioxidant activity of highly hydroxylated fullerene C60 and its interactions with the analogue of α-tocopherol	28
The molecular and physiological consequences of cold plasma treatment in murine skin and its barrier function	28
Coenzyme Q redox signalling and longevity	27
Compromised immune/inflammatory responses in Rett syndrome	27
Suppressing long noncoding RNA OGRU ameliorates diabetic retinopathy by inhibition of oxidative stress and inflammation via miR-320/USP14 axis	27
Angiotensin II and leukocyte trafficking: New insights for an old vascular mediator. Role of redox-signaling pathways	27
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling	27
Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy	27
Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation	27
Manganese induces tumor cell ferroptosis through type-I IFN dependent inhibition of mitochondrial dihydroorotate dehydrogenase	27
Antioxidant function of phytocannabinoids: Molecular basis of their stability and cytoprotective properties under UV-irradiation	27
Timosaponin BII improved osteoporosis caused by hyperglycemia through promoting autophagy of osteoblasts via suppressing the mTOR/NFκB signaling pathway	26
Gamma irradiation promotes chemo-sensitization potential of gallic acid through attenuation of autophagic flux to trigger apoptosis in an NRF2 inactivation signalling pathway	26
Activation of MAT2A-ACSL3 pathway protects cells from ferroptosis in gastric cancer	26
Myricetin prevents high molecular weight Aβ1-42 oligomer-induced neurotoxicity through antioxidant effects in cell membranes and mitochondria	26
Nrf2 contributes to the benefits of exercise interventions on age-related skeletal muscle disorder via regulating Drp1 stability and mitochondrial fission	26
Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate experimental non-alcoholic steatohepatitis via Nrf2/NQO-1 pathway	26
Osteosarcoma tissue-engineered model challenges oxidative stress therapy revealing promoted cancer stem cell properties	26
17β-estradiol ameliorates lipotoxicity-induced hepatic mitochondrial oxidative stress and insulin resistance	26
Sources and triggers of oxidative damage in neurodegeneration	26
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome	26
Antioxidant supplementation, redox deficiencies and exercise performance: A falsification design	26
Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency	26
High glucose-induced PRDX3 acetylation contributes to glucotoxicity in pancreatic β-cells: Prevention by Teneligliptin	25
Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission	25
Oxidative stress, telomeres and cellular senescence: What non-drug interventions might break the link?	25
Oxidative stress-induced aberrant lipid metabolism is an important causal factor for dysfunction of immunocytes from patients with systemic lupus erythematosus	25
ACSL4 and the lipoxygenases 15/15B are pivotal for ferroptosis induced by iron and PUFA dyshomeostasis in dopaminergic neurons	25
Oxidative stress induces downregulation of TP53INP2 and suppresses osteogenic differentiation of BMSCs during osteoporosis through the autophagy degradation pathway	25
Enhanced activity of glycolytic enzymes in Drosophila and human cell models of Parkinson's disease based on DJ-1 deficiency	25
Melatonin inhibits the apoptosis of rooster Leydig cells by suppressing oxidative stress via AKT-Nrf2 pathway activation	25
Genetic elucidation of hydrogen signaling in plant osmotic tolerance and stomatal closure via hydrogen sulfide	25
Selenoprotein P – Selenium transport protein, enzyme and biomarker of selenium status	25
The photodynamic and direct actions of methylene blue on mitochondrial energy metabolism: A balance of the useful and harmful effects of this photosensitizer	25
Sirtuin 3: Emerging therapeutic target for cardiovascular diseases	25
Anti-ageing effects of ubiquinone and ubiquinol in a senescence model of human dermal fibroblasts	25
The intestinal 3M (microbiota, metabolism, metabolome) zeitgeist – from fundamentals to future challenges	25
Nitrate from diet might fuel gut microbiota metabolism: Minding the gap between redox signaling and inter-kingdom communication	25