OOIR: Observatory of International Research

Papers

(The H4-Index of Free Radical Biology and Medicine is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)

Article	Citations
Catalase post-translational modifications as key targets in the control of erythrocyte redox homeostasis in children with obesity and insulin resistance	271
Activation of autophagy attenuates motor deficits and extends lifespan in a C. elegans model of ALS	169
Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain	151
Muscle regeneration and muscle stem cells in metabolic disease	142
Multifunctional peptide-drug conjugate CORM-401@R9: A novel approach to combat oxidative stress in cataracts	142
Bruton tyrosine kinase promotes wound healing after myocardial infarction by inhibiting the transcription of u-PA	141
The therapeutic potential of recombinant ANGPTL4 in Parkinson's disease: Evidence from in vivo and in vitro studies	139
Deciphering the role of skin aging in pigmentary disorders	132
Ginsenoside Re attenuates memory impairments in aged Klotho deficient mice via interactive modulations of angiotensin II AT1 receptor, Nrf2 and GPx-1 gene	123
Lipid overload impairs hepatic VLDL secretion via oxidative stress-mediated PKCδ-HNF4α-MTP pathway in large yellow croaker (Larimichthys crocea)	120
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy	119
CCT3 suppression prompts apoptotic machinery through oxidative stress and energy deprivation in breast and prostate cancers	119
Effects of sugars, fatty acids and amino acids on cytosolic and mitochondrial hydrogen peroxide release from liver cells	111
CHIP-overexpressing Wharton's jelly-derived mesenchymal stem cells attenuate hyperglycemia-induced oxidative stress-mediated kidney injuries in diabetic rats	110
Male minipuberty involves the gonad-independent activation of preoptic nNOS neurons	109
Corrigendum to “Melatonin alleviates early brain injury by inhibiting the NRF2-mediated ferroptosis pathway after subarachnoid hemorrhage” [Free Radic. Biol. Med. 208 (2023) 555–570]	106
Therapeutic potential of plasma-treated solutions in atopic dermatitis	105
Mouse models used to test the role of reactive oxygen species in aging and age-related chronic diseases	105
Sevoflurane exposure accelerates the onset of cognitive impairment via promoting p-Drp1S616-mediated mitochondrial fission in a mouse model of Alzheimer's disease	105
Bioavailability of mango (poly)phenols: An evaluation of the impact of the colon, and phenylalanine and tyrosine on the production of phenolic catabolites	101
Influenza A virus-induced glycolysis facilitates virus replication by activating ROS/HIF-1α pathway	99
Human salivary histatin 1 regulating IP3R1/GRP75/VDAC1 mediated mitochondrial-associated endoplasmic reticulum membranes (MAMs) inhibits cell senescence for diabetic wound repair	98
A critical role for microglia in regulating metabolic homeostasis and neural repair after spinal cord injury	98
CREBRF regulates apoptosis and estradiol via ISG15/ISGylation in pig granulosa cells	98
Edaravone Dexborneol protects against blood-brain barrier disruption following cerebral ischemia/reperfusion by upregulating pericyte coverage via vitronectin-integrin and PDGFB/PDGFR-β signaling	92

Oral administration of plumbagin is beneficial in in vivo models of Duchenne muscular dystrophy through control of redox signaling	91
Effect of peroxiredoxin 1 or peroxiredoxin 2 knockout on the thiol proteome of Jurkat cells	90
Indoleamine 2, 3-dioxygenase 1 aggravates acetaminophen-induced acute liver failure by triggering excess nitroxidative stress and iron accumulation	89
WITHDRAWN: Up-regulation of VSIG4 alleviates kidney transplantation-associated acute kidney injury through suppressing inflammation and ROS via regulation of AKT signaling	89
Peroxiporins: can they modulate cancer resistance?	83
Mitochondria signaling to the epigenome: A novel role for an old organelle	83
Dimethylglycine and B-vitamins administration counteracts the inflammatory and oxidative state in autism spectrum disorders	79
Redox and lipidomic analysis of human brain microvascular endothelial cells (hCMEC/D3) adapted to physiological oxygen levels	79
TRAF6 inhibition is a potential therapeutic target to suppress cardiovascular inflammation in animals with arterial hypertension	78
Human 3D full skin models coupled with advanced bio-markers assessment for the efficacy evaluation of topical redox modulators	78
Redox signalling regulates Jagged1 intracellular domain fragment formation, altering endothelial cell cycle, adhesion, and extracellular matrix	77
Quantum sensing of free radicals in semen: Investigating the role of oxidative stress in idiopathic male infertility	76
Targeting mitochondrial biogenesis with nitro-oleic acid has protective effects on murine cardiomyocytes under metabolic stress	76
Development of a non-animal testing method using genetically engineered biosensors for assessing skin sensitizers	76
Therapeutic targeting of NRF2 in Alzheimer's disease	73
Observing dynamics in life sciences	72
Formation of di-tryptophan dimers by radical-radical reactions	71
Effects of the dipeptide of active site CXXC motif on mitochondrial Erv1/ALR activity	70
Redox regulation by coenzyme A	70
MESSAGE Mission: Understanding the immune system and cancer connection in microgravity	68
The use of systems biology in treatment of metabolic diseases	68
Role of NRF2 in Protective Effects of the Electrophilic Metabolite of Docosahexaenoic Acid against UVB-induced Oxidative Cell Death and Inflammation in Mouse Skin	65
A biosensor-based approach for the determination of hydrogen peroxide in biological samples	65
Oxidative damage in reperfusion after stroke: ferroptosis and the role of the mitochondrial sodium/calcium exchanger NCLX	64
Compensatory increase in glutathione content as an adaptive response to oxidative stress in SH-SY5Y cells	63
A Platanus orientalis extract promotes the anti-senescent role of caveolin-1 via the amelioration of its DNA damage repair function	63
The Relationship between Mitochondrial Oxidative Stress and Huntington’s Disease Progression	63
The diagnosis potential of miRNAs in sepsis and their relation to oxidative stress	62
The Effects of Physical Activity on Gene-Specific Methylation of Antioxidant and Tumour Suppressor Genes in Post-surgery Female Breast Cancer Patients Undergoing Medical Treatment	62
Dual NOX4/NOX1 inhibition by setanaxib halts cholangiocarcinoma progression by impairing cancer associated fibroblast activation	61
The oxidatively damaged DNA and amyloid-β oligomer hypothesis of Alzheimer's disease	60
Utility of selenocyanate to modulate cellular damage induced by myeloperoxidase during chronic inflammation.	60
Selenoprotein P increases upon selenium and coenzyme Q10 supplementation and is associated with telomere length, quality of life and reduced inflammation and mortality	59
The phenol red compound: A potential artifact in pharmacological induction of ferroptosis	59