OOIR: Observatory of International Research

Papers

(The H4-Index of Free Radical Biology and Medicine is 62. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Human 3D full skin models coupled with advanced bio-markers assessment for the efficacy evaluation of topical redox modulators	281
The use of systems biology in treatment of metabolic diseases	228
Peroxiporins: can they modulate cancer resistance?	223
The Relationship between Mitochondrial Oxidative Stress and Huntington’s Disease Progression	192
Oxidative damage in reperfusion after stroke: ferroptosis and the role of the mitochondrial sodium/calcium exchanger NCLX	189
Editorial Board	158
Exploring the non-toxic therapeutic potential of dioscorea communis in combating oral pathogenic bacteria and their effect on hard and soft oral tissues	143
Characterization of immunogenic MDA-lipidperoxidation epitopes on human plasma extracellular vesicles recognized by a human monoclonal IGM-antibody	143
Lipid-derived electrophiles induce carbonyl stress, mitochondrial dysfunction, and cellular senescence: 4-hydroxynonenal as a physiological determinant of adipose senescence in obesity and aging	126
A comprehensive LC-MS/MS approach for the monitoring of oxidative stress markers in gingival samples	123
GSNOR drives age-related obesity by regulating the S-nitrosation of Beclin-1 to promote adipose tissue whitening	120
Short-term blockade of E-prostanoid 3 receptor curbs necroinflammation and protects against I/R- and doxorubicin-induced acute myocardial injury	120
Fluorescence imaging for the progression of oxidative stress-related diseases	119
Redox resilience in hypoxia-tolerant Tenebrio molitor larvae	116
Mouse models used to test the role of reactive oxygen species in aging and age-related chronic diseases	115
Role of Coenzyme Q10 in mitochondrial dysfunction and oxidative damage in RETT syndrome	112
Effect of Thermal Processing and Oxygen concentration on the Phenolic Composition and Inhibition of Advanced Glycation End Products of Chilean Beans (Phaseolus vulgaris) Extracts	106
Spatial transcriptomic profiling and selenoprotein expression in mouse brain following glucocorticoid administration	104
E2/E3-independent ubiquitin-like protein conjugation by Urm1 is coupled to cysteine persulfidation and protects the proteome under oxidative stress	103
Constitutive activation of NLRP3 inflammasome machinery in ex-vivo models of Rett syndrome: from pathogenetic role to new potential therapeutic target	100
Crowding modulates the oxidant-induced cross-linking and aggregation of the key glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase	100
Metabolic Adaptations to Stress and Senescence in the Epidermis	99
Analysis of a planar catechin analog on cancer cellular inhibition	99
Oxidation and chlorination of human amylin induces chemical and structural changes and formation of immunogenic products	98
Nitrogen Oxide-derived Anti-inflammatory Lipid Signaling Mediators	97

L-2-hydroxyglutaric Acid Intracerebroventricular Administration to Neonatal Rats Promotes Disturbance of Redox Homeostasis, Neuronal Death, Glial Reactivity and Delayed Myelination	89
H3.1Cys96 oxidation promotes H3 variant exchange, chromatin remodeling, and breast cancer cell phenotypic plasticity	86
Hypochlorous acid-mediated modification of proteins and its consequences	83
The role of nitric oxide in autism spectrum disorder	82
Quantitative imaging of signaling with genetically encoded biosensors to study signaling in plants, yeast, and human cells	81
Increased intracellular persulfide levels attenuate HlyU-mediated hemolysin transcriptional activation in Vibrio cholerae	79
Green Tea Polyphenols Protect against Genotoxic Damage and Modulate Endogenous Antioxidant Defenses in Hsd:ICR Mice Exposed to Hexavalent Chromium	79
Alterations In Redox Homeostasis And Mitochondrial Dynamics In Liver Of MPS II Mice	79
NoxO1 and Erbin - a cooperation to control EGF signaling in cancer ?	79
AKR1A1 controls redox and metabolic adaptation of renal and hepatocellular carcinoma	78
Dynamics of plasma membrane repair upon oxidative damage	75
Selective inhibition of GSK3? mediates an Nrf2-independent anti-inflammatory microglial response	75
Hydrogen peroxide diffusion across human red blood cell membranes is not facilitated by aquaporins	74
Impaired Metabolic and Inflammatory Responses in a Murine Model of Leigh Syndrome	73
Arachidonic acid-derived lipoxin A4 yields an electrophilic 15-oxo metabolite that induces anti-inflammatory responses independent of FPR2 receptor signaling	73
Antiproliferative Effect of Novel Phenolic Antioxidant TS-13 in vitro	72
Site-Specific Tyrosine Nitration of Heat Shock Protein 90 Plays Distinct Roles in Glioblastoma Multiforme	72
The stability and degradation products of polyhydroxy flavonols in boiling water	71
Shielding of Phospholipid Oxidation by 5,7-unsaturated Sterol Metabolites	70
Heme nitrosyl complexes: insights into protein/protein transfer and cell trafficking	70
Endothelial cells derived from elephant seals respond to extended hypoxia by suppressing inflammation and conserving glutathione	70
Adjunctive effects with continual X-ray irradiation for effective photodynamic therapy	68
Characterization of human mitochondrial aconitase and its interaction with frataxin	68
Synthesis and Applications of Metal Organic Frameworks in Photodynamic Therapy	67
7-Dehydrocholesterol protects membrane phospholipids from oxidation	67
Extracellular Superoxide Dismutase Regulation of Metabolism and Oxidative Stress in Pulmonary Artery Smooth Muscle Cells	66
Regulation of ERK1/2 Phosphorylation, Oxidation, and Cell Cycle Progression by Miro1 Mediated Mitochondrial Positioning	66
Radiation-induced Glioblastoma Extracellular Vesicles Containing 4HNE Promote Microglia-Mediated Neurotoxicity	65
A Role for NRF2 in the Lung Epithelial Cell Response to Wood Smoke	64
Oxidative Stress Is Higher In Women With Sarcopenic Obesity	64
ANG secretion predisposes endothelial cells toward angiogenesis in FIN56-induced ferroptotic hepatocellular carcinoma via the BMP6/ID1 signaling pathway	63
miRNAome-metabolome wide association study reveals effects of miRNA regulation in male diabetic erectile dysfunction	63
Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility	63
Isotope-labeled ergothioneine clarifies the mechanism of reaction with singlet oxygen	63
Antioxidants Fail to Prevent Glucose Hypometabolism-Induced Neural Cell Death, Unlike Dimethyl-2-oxoglutarate: Implications in Alzheimer’s Disease	62
Investigation of Nrf2-Keap-1 and Sestrin-2 Pathways in Hidradenitis Suppurativa Patient Sera	62
Cu Transport Proteins as Novel Therapeutic Targets for Cu-dependent Brain Endothelial Barrier Dysfunction and Cuproptosis linked to Alzheimer’s Disease	62
The nitrone compound LQB122 improves adipogenesis and reduces obesity-associated metabolic risk	62