Genes & Development

Papers
(The TQCC of Genes & Development is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
NDF is a transcription factor that stimulates elongation by RNA polymerase II317
Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling159
A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels117
Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae111
The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination106
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma84
ALL-tRNAseq enables robust tRNA profiling in tissue samples84
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer80
RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity65
RUNX1 is required in granulocyte–monocyte progenitors to attenuate inflammatory cytokine production by neutrophils63
ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation57
A nonneural miRNA cluster mediates hearing via repression of two neural targets56
Molecular basis of mRNA transport by a kinesin-1–atypical tropomyosin complex55
How do genomes encode developmental time?54
RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription53
Corrigendum: Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells52
CDK4loss-of-function mutations cause microcephaly and short stature49
The evolving tale of Pol2 function49
Minding the message: tactics controlling RNA decay, modification, and translation in virus-infected cells49
Notch induces transcription by stimulating release of paused RNA polymerase II47
Metabolic partitioning in the brain and its hijacking by glioblastoma46
Oct4 redox sensitivity potentiates reprogramming and differentiation44
The biological underpinnings of therapeutic resistance in pancreatic cancer42
The evolution of metazoan shelterin41
Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states41
Histone bivalency regulates the timing of cerebellar granule cell development40
Systematic functional characterization of antisense eRNA of protocadherin α composite enhancer40
Recognition of acetylated histone by Yaf9 regulates metabolic cycling of transcription initiation and chromatin regulatory factors40
USP7 substrates identified by proteomics analysis reveal the specificity of USP738
Letters to the Editor38
Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain37
Unraveling the complexity of thermogenic remodeling of white fat reveals potential antiobesity therapies37
Proteomic insights into circadian transcription regulation: novel E-box interactors revealed by proximity labeling35
Tolerance thresholds underlie responses to DNA damage during germline development35
Opening the window for endothelial-to-hematopoietic transition35
TBX2 controls a proproliferative gene expression program in melanoma34
Corrigendum: Identification of a PTEN-regulated STAT3brain tumor suppressor pathway33
LINE-1, the NORth star of nucleolar organization32
ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy32
Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma31
E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic β cells31
How Terri Grodzicker transformedGenes & Development31
H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats31
PROSER1 modulates DNA demethylation through dual mechanisms to prevent syndromic developmental malformations30
REST is a major negative regulator of endocrine differentiation during pancreas organogenesis30
Cancer neuroscience at the brain–body interface29
Implications of inhibition of Rev1 interaction with Y family DNA polymerases for cisplatin chemotherapy29
BMAL1 drives muscle repair through control of hypoxic NAD+ regeneration in satellite cells28
Traveling with Terri: bacterial communities28
Deciphering visceral instincts: a scientific quest to unravel food choices from molecules to mind28
An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma28
Reflections on Terri28
Multiomics analysis of the NAD+–PARP1 axis reveals a role for site-specific ADP-ribosylation in splicing in embryonic stem cells27
RBBP6 activates the pre-mRNA 3′ end processing machinery in humans27
Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance27
TG andG&D: some thoughts and reminiscences26
NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD426
A germline PAF1 paralog complex ensures cell type-specific gene expression26
Comprehensive mapping of cell fates in microsatellite unstable cancer cells supports dual targeting of WRN and ATR26
An Editor's rave review26
ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD26
Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins25
Noncatalytic regulation of 18SrRNA methyltransferase DIMT1 in acute myeloid leukemia25
Anticipating resistance to KRAS inhibition: a novel role for USP21 in macropinocytosis regulation25
Corrigendum: Functional rejuvenation of aged neural stem cells by Plagl2 and anti-Dyrk1a activity23
Corrigendium: Effects of RAS on the genesis of embryonal rhabdomyosarcoma23
Transcription factors specifically control change23
Features and mechanisms of canonical and noncanonical genomic imprinting22
Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain21
Therapeutic targeting of RNA for neurological and neuromuscular disease21
Introduction: 35 years on21
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype20
BRCA1 and BRCA2: from cancer susceptibility to synthetic lethality20
Advancing therapeutics using antibody-induced dimerization of receptor tyrosine phosphatases20
From fat to fear: how lipid powers cancer spread19
Spore germination: Two ion channels are better than one19
SPOC domain proteins in health and disease19
Guide RNA acrobatics: the one-for-two shuffle19
Balancing the scales: fine-tuning Polo-like kinase 4 to ensure proper centriole duplication18
Circadian de(regulation) in physiology: implications for disease and treatment18
Genetic cold cases: lessons from solving complex congenital limb disorders18
IRX2 and NPTX1 differential regulation of β-catenin underlies MEK-mediated proliferation in human neuroglial cells18
The area postrema: a critical mediator of brain–body interactions18
The MYC–MAF–SAGA axis drives oncogenic gene expression in multiple myeloma17
Bridging brain and body in cancer17
The inner workings of replisome-dependent control of DNA damage tolerance16
Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation16
Distinct accessory roles ofArabidopsisVEL proteins in Polycomb silencing16
The lncRNAMalat1is trafficked to the cytoplasm as a localized mRNA encoding a small peptide in neurons16
SpoVAF and FigP assemble into oligomeric ion channels that enhance spore germination16
Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells16
A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer15
Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus15
Small RNAs guide histone methylation in Arabidopsis embryos15
Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication15
Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression15
Terri Grodzicker: the quintessential scientist–Editor15
Genes and my development15
Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation15
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