Genes & Development

Papers
(The TQCC of Genes & Development is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Folding makes an imprint243
In vivo temporal resolution of acute promyelocytic leukemia progression reveals a role of Klf4 in suppressing early leukemic transformation164
Comparing the roles of sex chromosome-encoded protein homologs in gene regulation121
RUNX1 is required in granulocyte–monocyte progenitors to attenuate inflammatory cytokine production by neutrophils98
Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion90
Interfaces between cellular responses to DNA damage and cancer immunotherapy90
Arrested development: the dysfunctional life history of medulloblastoma87
NDF is a transcription factor that stimulates elongation by RNA polymerase II79
Making a journal great: an ode to Terri Grodzicker71
TG andG&D: some thoughts and reminiscences70
An Editor's rave review65
My pearl anniversary withGenes & Development,30 years on…63
Totipotency, development, and chromatin62
RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity59
Corrigendum: In vivo CRISPR screening for phenotypic targets of the mir-35-42 family in C. elegans58
Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae51
Corrigendium: Effects of RAS on the genesis of embryonal rhabdomyosarcoma47
Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain45
DiverseFgfr1signaling pathways and endocytic trafficking regulate mesoderm development45
Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain44
Features and mechanisms of canonical and noncanonical genomic imprinting44
HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation43
The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination41
Molecular basis for PHF7-mediated ubiquitination of histone H341
Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans41
Building a circuit through correlated spontaneous neuronal activity in the developing vertebrate and invertebrate visual systems41
A germline PAF1 paralog complex ensures cell type-specific gene expression40
A nonneural miRNA cluster mediates hearing via repression of two neural targets40
Interoceptive inference and prediction in food-related disorders39
Consolidating roles of neuroimmune reflexes: specificity of afferent, central, and efferent signals in homeostatic immune networks39
Decoding biology with massively parallel reporter assays and machine learning39
Psat1-generated α-ketoglutarate and glutamine promote muscle stem cell activation and regeneration38
Anticipating resistance to KRAS inhibition: a novel role for USP21 in macropinocytosis regulation38
Mesenchymal stromal cells as conductors of adipose tissue remodeling36
Molecular basis of mRNA transport by a kinesin-1–atypical tropomyosin complex36
Transcription factors specifically control change36
Regularly spaced tyrosines in EBF1 mediate BRG1 recruitment and formation of nuclear subdiffractive clusters34
Nopp140-chaperoned 2′-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity33
Dynamics in Fip1 regulate eukaryotic mRNA 3′ end processing33
Corrigendum: Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination32
Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins32
Unique role for lncRNA HOTAIR in defining depot-specific gene expression patterns in human adipose-derived stem cells32
Xrn2 substrate mapping identifies torpedo loading sites and extensive premature termination of RNA pol II transcription31
The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8+ cytotoxic T-cell response31
Disruption of origin chromatin structure by helicase activation in the absence of DNA replication30
Balancing act of a leading strand DNA polymerase-specific domain and its exonuclease domain promotes genome-wide sister replication fork symmetry30
Peripheral clocks tick independently of their master30
Localization ofKif1cmRNA to cell protrusions dictates binding partner specificity of the encoded protein30
A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels29
Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling29
Structural and biochemical analyses of the nuclear IκBζ protein in complex with the NF-κB p50 homodimer28
Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals26
Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells26
Noncatalytic regulation of 18SrRNA methyltransferase DIMT1 in acute myeloid leukemia26
Corrigendum: The evolutionary turnover of recombination hot spots contributes to speciation in mice26
Hepatic GATA4 regulates cholesterol and triglyceride homeostasis in collaboration with LXRs25
An old dog with new tricks: TFEB promotes syncytin expression and cell fusion in the human placenta25
An FGF timer for zygotic genome activation24
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer24
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma24
ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation23
Identification and characterization of conserved noncoding cis-regulatory elements that impact Mecp2 expression and neurological functions23
Neural stem/precursor cells dynamically change their epigenetic landscape to differentially respond to BMP signaling for fate switching during brain development23
Coming in from the cold: overcoming the hostile immune microenvironment of medulloblastoma22
ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease22
ALL-tRNAseq enables robust tRNA profiling in tissue samples22
Corrigendum: Functional rejuvenation of aged neural stem cells by Plagl2 and anti-Dyrk1a activity22
Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing21
ESRP2–microRNA-122 axis promotes the postnatal onset of liver polyploidization and maturation21
Enzymatic reactions of AGO4 in RNA-directed DNA methylation: siRNA duplex loading, passenger strand elimination, target RNA slicing, and sliced target retention21
Erratum: Meikin synergizes with shugoshin to protect cohesin Rec8 during meiosis I21
The transcription factor activity gradient (TAG) model: contemplating a contact-independent mechanism for enhancer–promoter communication21
Metabolic partitioning in the brain and its hijacking by glioblastoma21
Advancing therapeutics using antibody-induced dimerization of receptor tyrosine phosphatases21
Corrigendum: Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells20
Intron lariat spliceosomes convert lariats to true circles: implications for intron transposition20
The evolving tale of Pol2 function20
SPOC domain proteins in health and disease19
Protein domains of low sequence complexity—dark matter of the proteome19
It's complicated: the interplay ofKif1cmRNA localization in cell protrusions, assembly of protein binding partners on the KIF1C protein, and cell migration19
NFATC2IP is a mediator of SUMO-dependent genome integrity19
The dual nature of the nucleolus18
Guide RNA acrobatics: the one-for-two shuffle18
Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer18
Coupling crossover and synaptonemal complex in meiosis18
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype18
The Zip4 protein directly couples meiotic crossover formation to synaptonemal complex assembly18
Epigenetic modulators provide a path to understanding disease and therapeutic opportunity17
You can be an editor too!17
A synthetic KLHL20 ligand to validate CUL3KLHL20as a potent E3 ligase for targeted protein degradation17
Terri Grodzicker and the making ofGenes & Development17
Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster17
A model for Scc2p stimulation of cohesin's ATPase and its inhibition by acetylation of Smc3p17
Protein phosphatase 4 controls circadian clock dynamics by modulating CLOCK/BMAL1 activity17
Terri Grodzicker and her guidance through the elegance of adenovirus genetics17
Introduction: 35 years on17
Minding the message: tactics controlling RNA decay, modification, and translation in virus-infected cells16
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