Molecular and Cellular Probes

Article	Citations
Exosomes derived from human bone marrow mesenchymal stem cells transfer miR-222-3p to suppress acute myeloid leukemia cell proliferation by targeting IRF2/INPP4B	45
Aptamers, the bivalent agents as probes and therapies for coronavirus infections: A systematic review	39
Biosensor and molecular-based methods for the detection of human coronaviruses: A review	38
Construction and immunogenicity of a gE/gI/TK-deleted PRV based on porcine pseudorabies virus variant	36
Rapid and sensitive detection of potato virus X by one-step reverse transcription-recombinase polymerase amplification method in potato leaves and dormant tubers	33
miR-101-3p and miR-199b-5p promote cell apoptosis in oral cancer by targeting BICC1	33
Comparing the performance of conventional PCR, RTQ-PCR, and droplet digital PCR assays in detection of Shigella	28
MiR-646 prevents proliferation and progression of human breast cancer cell lines by suppressing HDAC2 expression	27
Rapid and visual detection of tomato spotted wilt virus using recombinase polymerase amplification combined with lateral flow strips	26
Administration with hyperoside sensitizes breast cancer cells to paclitaxel by blocking the TLR4 signaling	26
Development of a novel and rapid polymerase spiral reaction (PSR) assay to detect Salmonella in pork and pork products	25
Rapid analysis of Escherichia coli O157:H7 using isothermal recombinase polymerase amplification combined with triple-labeled nucleotide probes	25
The CCL2/CCL7/CCL12/CCR2 pathway is substantially and persistently upregulated in mice after traumatic brain injury, and CCL2 modulates the complement system in microglia	24
Nanobodies, the potent agents to detect and treat the Coronavirus infections: A systematic review	23
lncRNA XIST attenuates hypoxia-induced H9c2 cardiomyocyte injury by targeting the miR-122-5p/FOXP2 axis	21
Rapid diagnosis of largemouth bass ranavirus in fish samples using the loop-mediated isothermal amplification method	20
The role of miR-21/RECK in the inhibition of osteosarcoma by curcumin	20
Lycopene alleviates disc degeneration under oxidative stress through the Nrf2 signaling pathway	20
miR-1278 sensitizes nasopharyngeal carcinoma cells to cisplatin and suppresses autophagy via targeting ATG2B	19
MiR-202-5p attenuates neurological deficits and neuronal injury in MCAO model rats and OGD-induced injury in Neuro‐2a cells by targeting eIF4E-mediated induction of autophagy and inhibition of Akt/GSK	18
Simultaneous detection of classical swine fever virus and porcine circovirus 3 by SYBR green I-based duplex real-time fluorescence quantitative PCR	18
Multiplex qPCR assay for assessment of reference gene expression stability in rat tissues/samples	18
Development of a SYBR green I-based duplex real-time PCR assay for detection of pseudorabies virus and porcine circovirus 3	18
Circular RNA MTO1 suppresses tumorigenesis of gastric carcinoma by sponging miR‐3200-5p and targeting PEBP1	17
LncRNA PVT1 induces chondrocyte apoptosis through upregulation of TNF-α in synoviocytes by sponging miR-211-3p	17

Detection of porcine-derived ingredients from adulterated meat based on real-time loop-mediated isothermal amplification	16
Rapid and sensitive detection of potato virus Y by isothermal reverse transcription-recombinase polymerase amplification assay in potato	16
Induction of ferroptosis by carnosic acid-mediated inactivation of Nrf2/HO-1 potentiates cisplatin responsiveness in OSCC cells	16
Genome-wide analysis of mRNAs and lncRNAs in Mycoplasma bovis infected and non-infected bovine mammary gland tissues	16
The knockdown of MALAT1 inhibits the proliferation, invasion and migration of hemangioma endothelial cells by regulating MiR-206 / VEGFA axis	16
Development of lateral flow assay combined with recombinase polymerase amplification for highly sensitive detection of Dickeya solani	16
miR-1184 regulates the proliferation and apoptosis of colon cancer cells via targeting CSNK2A1	16
Lung resided monocytic myeloid-derived suppressor cells contribute to premetastatic niche formation by enhancing MMP-9 expression	16
The fluorescent probe-based recombinase-aided amplification for rapid detection of Escherichia coli O157:H7	16
Krüppel-like factors family regulation of adipogenic markers genes in bovine cattle adipogenesis	16
Computational formulation and immune dynamics of a multi-peptide vaccine candidate against Crimean-Congo hemorrhagic fever virus	16
Knockdown of TRIM47 inhibits glioma cell proliferation, migration and invasion through the inactivation of Wnt/β-catenin pathway	15
LncRNA AFAP1-AS1 contributes to the progression of endometrial carcinoma by regulating miR-545-3p/VEGFA pathway	14
Repression of miR-142–3p alleviates psoriasis-like inflammation by repressing proliferation and promoting apoptosis of keratinocytes via targeting Sema3A	14
A highly sensitive semi-nested real-time PCR utilizing oligospermine-conjugated degenerate primers for the detection of diverse strains of small ruminant lentiviruses	14
Periostin aggravates NLRP3 inflammasome-mediated pyroptosis in myocardial ischemia-reperfusion injury	14
Development of qPCR platform with probes for quantifying prevalent and biomedically relevant human gut microbial taxa	14
Circ_002664/miR-182–5p/Herpud1 pathway importantly contributes to OGD/R-induced neuronal cell apoptosis	14
Sequence mismatch in PCR probes may mask the COVID-19 detection in Nepal	14
LINC00346 regulates glycolysis by modulation of glucose transporter 1 in breast cancer cells	13
One-step multiplex TaqMan probe-based method for real-time PCR detection of four canine diarrhea viruses	13
Development of a real-time reverse transcription recombinase polymerase amplification assay for rapid detection of spring viremia of carp virus	13
DNA and eDNA-based tracking of the North African sharptooth catfish Clarias gariepinus	13
Development of a reverse transcription droplet digital PCR assay for sensitive detection of peach latent mosaic viroid	12
Evaluation of miRNA-21-5p and miRNA-10b-5p levels in serum-derived exosomes of breast cancer patients in different grades	12
Development and validation of a new triplex real-time quantitative reverse Transcriptase-PCR assay for the clinical detection of SARS-CoV-2	12
EPHA5 mutation impairs natural killer cell-mediated cytotoxicity against non-small lung cancer cells and promotes cancer cell migration and invasion	12
Up-regulated miR-374a-3p relieves lipopolysaccharides induced injury in CHON-001 cells via regulating Wingless-type MMTV integration site family member 5B	12
A multiplex PCR assay for the detection of five human pathogenic Vibrio species and Plesiomonas	12
Determination of nitrogen deficiency-related microRNAs in plants using fluorescence quenching of graphene oxide nanosheets	12
DNA/Nano based advanced genetic detection tools for authentication of species: Strategies, prospects and limitations	12
Overexpression of miR-133a-3p inhibits fibrosis and proliferation of keloid fibroblasts by regulating IRF5 to inhibit the TGF-β/Smad2 pathway	12
Development of a Recombinase Polymerase Amplification (RPA) assay for acute hepatopancreatic necrosis disease (AHPND) detection in Pacific white shrimp (Penaeus vannamei)	12
Extracellular vesicles derived from dental mesenchymal stem/stromal cells with gemcitabine as a cargo have an inhibitory effect on the growth of pancreatic carcinoma cell lines in vitro	11
TaqMan-based real-time polymerase chain reaction assay for specific detection of bocavirus-1 in domestic cats	11
Sp1 promotes dental pulp stem cell osteoblastic differentiation through regulating noggin	11
Characteristics of Vibrio vulnificus isolates from clinical and environmental sources	11
miR-410-5p promotes the development of diabetic cardiomyopathy by suppressing PIM1-induced anti-apoptosis	11
Development of a new TaqMan-based PCR assay for the specific detection and quantification of Simkania negevensis	11
Point of care diagnosis of plant virus: Current trends and prospects	11
Anti-inflammatory drugs as new inhibitors to xanthine oxidase: In vitro and in silico approach	11
Aldosterone alleviates lipopolysaccharide-induced acute lung injury by regulating epithelial sodium channel through PI3K/Akt/SGK1 signaling pathway	10
Rapid detection of peach latent mosaic viroid by reverse transcription recombinase polymerase amplification	10
In-silico characterization and RNA-binding protein based polyclonal antibodies production for detection of citrus tristeza virus	10
Simultaneous differentiation and diagnosis of goose parvovirus and astrovirus in clinical samples with duplex SYBR Green I real-time PCR	10
miR-203 suppresses pancreatic cancer cell proliferation and migration by modulating DUSP5 expression	10
Enzymatic recombinase amplification coupled with CRISPR-Cas12a for ultrasensitive, rapid, and specific Porcine circovirus 3 detection	10
YY1-mediated PTEN dephosphorylation antagonizes IR-induced DNA repair contributing to tongue squamous cell carcinoma radiosensitization	10
Detection of Carp pox virus (CyHV-1) from koi (Cyprinus carpio L.) in Iran; clinico-pathological and molecular characterization	10
An HFman probe-based reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for HIV-1 detection	10

Development of a duplex SYBR GreenⅠ based real-time PCR assay for detection of porcine epidemic diarrhea virus and porcine bocavirus3/4/5	10
A real-time PCR assay for detection of emerging infectious Elizabethkingia miricola	9
Selection of stable reference genes for gene expression analysis in sweet potato (Ipomoea batatas L.)	9
Thermodynamic evaluation of the impact of DNA mismatches in PCR-type SARS-CoV-2 primers and probes	9
circNup188/miR-760–3p/Map3k8 axis regulates inflammation in cerebral ischemia	9
Quantitative evaluation of PpSP15-LmSTI1 fusion gene expression following transfection with an alphavirus-derived self-amplifying mRNA and conventional DNA vaccine platforms	9
Aptamer-based biosensors for Pseudomonas aeruginosa detection	9
MiRNA-301b-3p induces proliferation and inhibits apoptosis in AML cells by targeting FOXF2 and regulating Wnt/β-catenin axis	9
Exendin-4 regulates endoplasmic reticulum stress to protect endothelial progenitor cells from high-glucose damage	9
Restoration of miR-143 reduces migration and proliferation of bladder cancer cells by regulating signaling pathways involved in EMT	9
Garcinol protects against cerebral ischemia-reperfusion injury in vivo and in vitro by inhibiting inflammation and oxidative stress	9
Insulin-like growth factor-I activates NFκB and NLRP3 inflammatory signalling via ROS in cancer cells	9
A novel CNS-homing peptide for targeting neuroinflammatory lesions in experimental autoimmune encephalomyelitis	9
Facile and direct detection of human papillomavirus (HPV) DNA in cells using loop-mediated isothermal amplification (LAMP)	8
Proteomic analysis of Brucella melitensis and Brucella ovis for identification of virulence factor using bioinformatics approachs	8
PTPN14 acts as a candidate tumor suppressor in prostate cancer and inhibits cell proliferation and invasion through modulating LATS1/YAP signaling	8
The genomic constellation of a novel duck reovirus strain associated with hemorrhagic necrotizing hepatitis and splenitis in Muscovy ducklings in Fujian, China	8
Early immune response in large yellow croaker (Larimichthys crocea) after immunization with oral vaccine	8
PVT1 induces NSCLC cell migration and invasion by regulating IL-6 via sponging miR-760	8
Establishment of a duplex SYBR green I-based real-time polymerase chain reaction assay for the rapid detection of canine circovirus and canine astrovirus	7
Recent advances of small molecule fluorescent probes for distinguishing monoamine oxidase-A and monoamine oxidase-B in vitro and in vivo	7
Application of recombinase polymerase amplification method for rapid detection of infectious laryngotracheitis virus	7
LncRNA GAS5 participates in the regulation of dexamethasone on androgen receptor -negative and -positive prostate cancer cell proliferation	7
MiR-34a suppresses the proliferation and invasion of gastric cancer by modulating PDL1 in the immune microenvironment	7
Molecular characterization of viruses found in honeybee (Apis mellifera) colonies infested with Varroa destructor and Nosema cerana in Egypt	7
Long non-coding RNA CRNDE deteriorates intrauterine infection-induced neonatal brain injury	7
Population genomics of honey bees reveals a selection signature indispensable for royal jelly production	7
Isolation and phylogenetic analysis of Getah virus from a commercial modified live vaccine against porcine reproductive and respiratory syndrome virus	7
Dexmedetomidine attenuates myocardial ischemia-reperfusion injury via inhibiting ferroptosis by the cAMP/PKA/CREB pathway	7
Selective growth of mosaic cells in chromosomal analysis of chorionic villi by conventional karyotyping	7
Perilipin2 inhibits diabetic nephropathy-induced podocyte apoptosis by activating the PPARγ signaling pathway	7
Comparing the efficiency of different Escherichia coli strains in producing recombinant capsid protein of porcine circovirus type 2	7
Development of PCR based assays for detection of lethal Holstein haplotype 1, 3 and 4 in Holstein Friesian cattle	7
Development of a pair of real-time loop mediated isothermal amplification assays for detection of Yersinia pestis, the causative agent of plague	7
Detection and genetic characteristics of porcine circovirus type 2 and 3 in Henan province of China	7
Knockdown of PLOD3 suppresses the malignant progression of renal cell carcinoma via reducing TWIST1 expression	7
The role of GtxA during Gallibacterium anatis infection of primary chicken oviduct epithelial cells	7
Fibroblast growth factor-2 ameliorates tumor necrosis factor-alpha-induced osteogenic damage of human bone mesenchymal stem cells by improving oxidative phosphorylation	7
Development and validation of a droplet digital PCR assay for the evaluation of PML-RARα fusion transcripts in acute promyelocytic leukemia	7
A TaqMan-MGB real-time RT-PCR assay with an internal amplification control for rapid detection of Muscovy duck reovirus	7
LncRNA AFAP1-AS1 promotes osteoblast differentiation of human aortic valve interstitial cells through regulating miR-155/SMAD5 axis	7
MicroRNA-330-3p represses the proliferation and invasion of laryngeal squamous cell carcinoma through downregulation of Tra2β-mediated Akt signaling	7
Overexpression of long non-coding RNA XIST promotes IL-1β-induced degeneration of nucleus pulposus cells through targeting miR-499a-5p	6
PDLIM2 acts as a cancer suppressor gene in non-small cell lung cancer via the down regulation of NF-κB signaling	6
Sensitively and quickly detecting Vibrio vulnificus by real time recombinase polymerase amplification targeted to vvhA gene	6
The obesity indices mediate the relationships of blood lipids and bone mineral density in Chinese elders	6
Metabogenomics reveals four candidate regions involved in the pathophysiology of Equine Metabolic Syndrome	6
Development and evaluation of a rapid detection assay for severe fever with thrombocytopenia syndrome virus based on reverse-transcription recombinase polymerase amplification	6
Magnetic bead flocculation test: Improving the diagnosis of tuberculous meningitis (TBM) in low-resource settings	6
Development and application of SYBR Green Ⅰ real-time quantitative reverse transcription PCR assay for detection of swine Getah virus	6
A rapid fluorescence-based real-time isothermal assay for the detection of Cucurbit yellow stunting disorder virus in squash and watermelon plants	6
Sensitive on-site detection of SARS-CoV-2 by ID NOW COVID-19	6
miR-708 affords protective efficacy in anoxia/reoxygenation-stimulated cardiomyocytes by blocking the TLR4 signaling via targeting HMGB1	6
The application of circulating tumor cell and cell-free DNA liquid biopsies in ovarian cancer	6
Multiplex real-time SYBR Green I PCR assays for simultaneous detection of 15 common enteric pathogens in stool samples	6
Development and preliminary testing of a probe-based duplex real-time PCR assay for the detection of African swine fever virus	6
Development of a recombinase polymerase amplification fluorescence assay to detect feline coronavirus	6
Identification of Brucella spp. isolates and discrimination from the vaccine strain Rev.1 by MALDI-TOF mass spectrometry	6
SOX30 confers a tumor suppressive effect in acute myeloid leukemia through inactivation of Wnt/β-catenin signaling	6
Evaluating two approaches for using positive control in standardizing the avian influenza H5 reverse transcription recombinase polymerase amplification assay	6
Novel universal primer-pentaplex PCR assay based on chimeric primers for simultaneous detection of five common pig viruses associated with diarrhea	6
The tricks for fighting against cancer using CAR NK cells: A review	6
Effects of hyperoxia exposure on the expression of Nrf2 and heme oxygenase-1 in lung tissues of premature rats	5
Reference gene selection for miRNA and mRNA normalization in potato in response to potato virus Y	5
Identification of stemness index-related long noncoding RNA SNHG12 in human bladder cancer based on WGCNA	5
miR-451a suppresses the development of breast cancer via targeted inhibition of CCND2	5
A method for early diagnosis of lung cancer from tumor originated DNA fragments using plasma cfDNA methylome and fragmentome profiles	5
Simultaneous detection of duck circovirus and novel goose parvovirus via SYBR green I-based duplex real-time polymerase chain reaction analysis	5
Digital PCR detection of EGFR somatic mutations in non-small-cell lung cancer formalin fixed paraffin embedded samples	5
Metagenomic next-generation sequencing for detection of pathogens in children with hematological diseases complicated with infection	5
Mitochondrial DNA copy number changes, heteroplasmy, and mutations in plasma-derived exosomes and brain tissue of glioblastoma patients	5
Development of a novel SYBR green I-based quantitative RT-PCR assay for Senecavirus A detection in clinical samples of pigs	5
Mapping molecular gene signatures mediated by SARS-COV-2 and large-scale and genome-wide transcriptomics comparative analysis among respiratory viruses of medical importance	5
Tumor-derived exosomal lincRNA ROR promotes angiogenesis in nasopharyngeal carcinoma	5
Two new rapid PCR-based methods for identification of Acinetobacter baumannii isolated from clinical samples	5
Expression level of VLDL receptor and VLDL-c levels in the malignant and benign breast tumors: The correlation with miRNA-4465 and miRNA-1297	5
Development of BruAb2_0168 based isothermal polymerase spiral reaction assay for specific detection of Brucella abortus in clinical samples	5
First detection and molecular identification of Anaplasma phagocytophilum in an introduced population of Reeve's muntjac (Muntiacus reevesi) in United Kingdom	5
Identification of genes associated with Kikuchi-Fujimoto disease using RNA and exome sequencing	4
A TaqMan probe-based multiplex real-time PCR method for the specific detection of wild type lumpy skin disease virus with beta-actin as internal amplification control	4

miR-451a suppresses papillary thyroid cancer cell proliferation and invasion and facilitates apoptosis through targeting DCBLD2 and AKT1	4
TM4SF19-AS1 facilitates the proliferation of lung squamous cell carcinoma by recruiting WDR5 to mediate TM4SF19	4
Design and development of a simple method for the detection and quantification of residual host cell DNA in recombinant rotavirus vaccine	4
PCR-based next-generation West Nile virus sequencing protocols	4
miR-544a Stimulates endometrial carcinoma growth via targeted inhibition of reversion-inducing cysteine-rich protein with Kazal motifs	4
Designing vaccine candidates against dengue virus by in silico studies on structural and nonstructural domains	4
DJ-1 alleviates anoxia and hypoglycemia injury in cardiac microvascular via AKT and GSH	4
A real-time recombinase polymerase amplification assay for fast and accurate detection of Ditylenchus destructor	4
Circulating metabolites in the early stage of breast cancer were not related to cancer stage or subtypes but associated with ki67 level. Promising statistical discrimination from controls	4
Epitope mapping of the White Spot Syndrome Virus (WSSV) VP28 monoclonal antibody through combined in silico and in vitro analysis reveals the potential antibody binding site	4
MiR-20a-5p suppressed TGF-β1-triggered apoptosis of human bronchial epithelial BEAS-2B cells by targeting STAT3	4
CircHIPK3 regulates melanoma cell behaviors by binding with miR-215–5p to upregulate YY1	4
Rapid in-situ detection kit (RisK): Development of loop-mediated isothermal amplification (LAMP) assay for the rapid identification of selected invasive alien fish in Malaysian freshwaters	4
LOC285194 inhibits proliferation of human keratinocytes through regulating miR-616/GATA3 pathway	4
High expression of eIF4A1 predicts unfavorable prognosis in clear cell renal cell carcinoma	4