Reproductive Toxicology

Article	Citations
EIF3D promotes the progression of preeclampsia by inhibiting of MAPK/ERK1/2 pathway	138
Ovarian toxicity of nanoparticles	73
Surveys as a valid tool for assessing food safety knowledge amongst pregnant women in high-income countries: a rapid review	65
Editorial Board	53
Whole mount preparation and analysis of rabbit mammary gland	50
Small extracellular vesicles derived from Nrf2-stimulated bone marrow mesenchymal stem cells ameliorated the testis damage and fertility disorder in doxorubicin-treated mice	44
Evaluation of reproductive toxicology studies according the OECD Guideline 443 – Claim and reality	42
A low dose of benzo(a)pyrene during prepuberty in male rats generated immediate oxidative stress in the testes and compromised steroidogenic enzymes/proteins	40
RETRACTED: Overexpressed miR-106b-5p promotes epithelial-mesenchymal transition in endometriosis by targeting PTEN	38
Extended one-generation reproductive toxicity study of food-grade titanium dioxide E171 with emphasis on reproductive and endocrine endpoints	37
Teratogenic and neuro-behavioural toxic effects of bisphenol A (BPA) and B (BPB) on Xenopus laevis development	37
Perfluorooctane sulfonic acid modulates expression of placental steroidogenesis-associated genes and hormone levels in pregnant rats	32
Epigallocatechin-3-gallate attenuates cyclophosphamide-induced damage in mouse ovarian tissue via suppressing inflammation, apoptosis, and expression of phosphorylated Akt, FOXO3a and rpS6	31
Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress	27
Risk assessment of dietary exposure to trace elements that are reproductive toxicants: Lead, molybdenum and nickel. The case study of Armenia	27
Bisphenol A-induced polycystic ovary syndrome (PCOS) with hormonal and metabolic implications in rats	26
Critical appraisal of the expert knowledge elicitation (EKE) methodology to identify uncertainties in building cumulative assessment groups for craniofacial alterations	26
Developmental exposure to an environmentally relevant dose of Bisphenol S impairs postnatal growth and disrupts placental transcriptional profile in female rat	25
Editorial Board	24
Comment on “Effects of the 2018 camp fire on birth outcomes in non-human primates: Case-control study”	23
Editorial Board	23
Perfluorooctane sulfonate and perfluorooctanoic acid induce plasma membrane dysfunction in boar spermatozoa during in vitro capacitation	22
Cigarette smoke is associated with up-regulation of inducible NOS and COX-2 protein expression and activity in granulosa cells of women undergoing in vitro fertilization	22
Causal association between 25-Hydroxyvitamin D and risk of abnormal spermatozoa: A bidirectional Mendelian randomization study	22
2,4-dichlorophenoxyacetic acid (2,4-D) exposure during postnatal development alters the effects of western diet on mouse prostate	21

Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells	21
Biological variability hampers the use of skeletal staining methods in zebrafish embryo developmental toxicity assays	21
Examination of piperonyl butoxide developmental toxicity as a Sonic hedgehog pathway inhibitor targeting limb and palate morphogenesis	21
Repeat-dose and embryo-fetal developmental toxicity of zinpentraxin alfa	20
Induced-damages on preantral follicles by withanolide D, a potent chemotherapy candidate are not attenuated by melatonin	20
Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum stress	20
Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube	19
Prenatal exposure to the phthalate DEHP impacts reproduction-related gene expression in the pituitary	19
Teratogenicity and Reactive Oxygen Species after transient embryonic hypoxia: Experimental and clinical evidence with focus on drugs causing failed abortion in humans	19
Effects of chronic CuNPs treatment followed by termination for two spermatogenic cycles in the testicular functions of mice	18
Antidepressant aripiprazole induces adverse effects on neural development during cortex organoid generation	18
Bisphenol A exposure advances puberty onset by changing Kiss1 expression firstly in arcuate nucleus at juvenile period in female rats	18
Prostate as a target of endocrine disrupting chemicals: Relevance, pathways, assays	18
Maternal trichloroethylene exposure and metabolic gene polymorphisms may interact during fetal cardiovascular malformation	18
Long-term transplantation human menstrual blood mesenchymal stem cell loaded collagen scaffolds repair endometrium histological injury	18
Teratogenic effects of voriconazole (anti-fungal drug) on Swiss albino mice	18
Toxicity from a single injection of human umbilical cord mesenchymal stem cells into rat ovaries	17
Editorial Board	16
Ascorbic acid modulates testicular toxicity of Ampligo® 150 ZC insecticide in male rabbit (Oryctolagus cuniculus)	16
Extended one generation reproductive toxicity study and effect on gut flora of genetically modified rice rich in β-carotene in wistar rats	16
Episodic ozone exposure in Long-Evans rats has limited effects on cauda sperm motility and non-coding RNA populations	16
Adverse Effects of Avobenzone on Boar Sperm Function: Disruption of Protein Kinase A Activity and Tyrosine Phosphorylation	16
Effects of di-(2-ethylhexyl) terephthalate on hypothalamus-pituitary-gonad axis in adult zebrafish	16
Evaluation of cytoprotective effects of cannabidiol on neuroinflammation and neurogenesis process in rat offsprings	15
The mechanisms of tripterygium glycosides-induced reproductive toxicity and detoxification strategies	15
Quaternary ammonium compound exposure causes infertility by altering endocrine signaling and gametogenesis	15
Effect of prenatal exposure to phthalates on birth weight of offspring: A meta-analysis	15
Exposure to Brominated Flame Retardants During Pregnancy and Lactation Increases the Prevalence of Breast Lesions and Cancer-Associated Pathways in Sprague-Dawley Rats	14
Current knowledge, challenges, new perspectives of the study, and treatments of Autism Spectrum Disorder	14
Contribution of ferritin and zinc to adverse infant outcomes among pregnancies with prenatal alcohol exposure in South Africa	14
Effect of Lactobacillus plantarum on folliculogenesis in deep frying oil-fed rats	14
Isoliquiritigenin ameliorates paroxetine-induced sexual dysfunction in male albino mice	14
The potential of mechanistic information organised within the AOP framework to increase regulatory uptake of the developmental neurotoxicity (DNT) in vitro battery of assays	14
Corrigendum to “Inhalation of ammonium sulfate and ammonium nitrate adversely affect sperm function” [Reproductive Toxicology, 96, (2020) 424–431]	14
The impact of isotretinoin on the pituitary-ovarian axis: An interpretative review of the literature	13
Trichlorfon blocks androgen synthesis and metabolism in rat immature Leydig cells	13
Impacts of heavy metal exposure on the prostate of murine models: Mechanisms of toxicity	13
Disruption of fetal eye development caused by insulin-induced maternal hypoglycemia in rats	13
Single cell RNA sequencing techniques and applications in research of ovary development and related diseases	13
Molecular mechanisms associated with embryotoxic effects of heavy metals in the Sea Urchin	13
Impact of Bisphenol A exposure on maternal gut microbial homeostasis, placental function, and fetal development during pregnancy	13
Maternal chronic caffeine intake impairs fertility, placental vascularization and fetal development in mice	13
Zebrafish embryos as a teratogenicity screening tool to reduce potential birth defects	13
Subacute high-refined carbohydrate diet leads to abnormal reproductive control of the hypothalamic-pituitary axis in female rats	12
Air pollution-linked epigenetic modifications in placental DNA: Prognostic potential for identifying future foetal anomalies	12
Maternal 129S1/SvImJ background attenuates the placental phenotypes induced by chronic paternal alcohol exposure	12
Association between polycyclic aromatic hydrocarbons and infertility in U.S. women: National Health and Nutrition Examination Survey 2013–2016	12
Neurotensin receptor-1 antagonist SR48692 modulation of high-fat diet induced reproductive impairment in male mice	12
Association between dietary intake estimated levels of PCDD/Fs and human sperm quality	12
Folate in maternal rheumatoid arthritis-filial autism spectrum disorder continuum	12

Safety of lactational exposure to venlafaxine on the rat mammary gland development and carcinogenesis in F1 female offspring	12
Effects of a TAML catalyst on mice exposed during pregnancy and lactation	12
Comprehensive digital documentation of teratology studies	12
Embryotoxicity of statins and other prescribed drugs with reported off-target effects on cholesterol biosynthesis	12
Propylparaben negatively impacts IN VITRO preimplantation mouse embryo development	11
Impact of endocrine disruptors from mother's diet on immuno-hormonal orchestration of brain development and introduction of the virtual human twin tool	11
Vanillin exerts therapeutic effects against hyperglycemia-altered glucose metabolism and purinergic activities in testicular tissues of diabetic rats	11
Associations between urinary and follicular fluid concentrations of phthalate metabolites and reproductive outcomes in Brazilian women undergoing fertility treatment	11
Zearalenone interferes with the sperm-triggered inflammation in the bovine uterus in vitro: Negative impact on sperm motility and survival	11
The endocrine disrupting effects of sodium arsenite in the rat testis is not mediated through macrophage activation	11
AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles	11
Placental BCRP transporter reduces cadmium accumulation and toxicity in immortalized human trophoblasts	11
Xeno-estrogenic activity of real-life mixtures of perfluoroalkylated substances in human placenta homogenates	10
Independent and interactive effects of air pollutants and ambient heat exposure on congenital heart defects	10
Prenatal caffeine consumption and neurobehavioral disorders - A systematic review	10
Fish oil supplementation protects against protein undernutrition-induced testicular and ovarian biochemical alterations in rats	10
Potential protective effect of beta-caryophyllene against cadmium chloride-induced damage to the male reproductive system in mouse	10
Protective role of hesperidin in finasteride-induced testicular toxicity in adult male Wistar rats: Insights into oxidative stress, apoptosis, and ultrastructure of seminiferous tubules	10
Effects of perinatal exposures to a TAML catalyst on the mammary gland and hormone-sensitive outcomes in male mice	10
Maternal preconception and pregnancy tobacco and cannabis use in relation to placental developmental markers: A population-based study	10
Subcutaneous zilucoplan: Evaluation of reproductive toxicology	10
Potential dual protective effects of melatonin on spermatogonia against hexavalent chromium	9
Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome	9
Effects of DDT and DDE on placental cholinergic receptors	9
Low levels of nicotine and cotinine but not benzo[a]pyrene induce human trophoblast cell proliferation	9
Considerations for and against dosing rodent pups before 7 days of age in juvenile toxicology studies	9
DNA methylation in polycystic ovary syndrome: Emerging evidence and challenges	9
Diuron-induced fetal Leydig cell dysfunction in in vitro organ cultured fetal testes	9
A dynamic in vitro developing testis model reflects structures and functions of testicular development in vivo	9
Exposure to di-isononyl phthalate during early pregnancy disrupts decidual angiogenesis and placental development in mice	9
The influence of lead exposure on male semen parameters: A systematic review and meta-analysis	9
Respiratory exposure to carbon black nanoparticles may induce testicular structure damage and lead to decreased sperm quality in mice	9
Editorial Board	9
Mechanisms underlying impaired spermatogenic function in orchitis induced by busulfan	9
Editorial Board	9
Shatavarin-IV rescues the Di (2-ethylhexyl) phthalate (DEHP) induced oxidative stress in rat granulosa cells in vitro	9
Advancing the use of new approach methodologies for assessing teratogenicity: Building a tiered approach	9
Exposure to Di-2-ethylhexyl phthalate (DEHP) and infertility in women, NHANES 2013-2016	9
Erroneous statement	8
Editorial Board	8
Editorial Board	8
Prenatal and postnatal exposure to polychlorinated biphenyls alter follicle numbers, gene expression, and a proliferation marker in the rat ovary	8
Prolonged exposure to rosuvastatin from pre-puberty to adulthood impairs sperm quality in mice and leads to paternally mediated developmental toxicity	8
The effect of adipose-derived mesenchymal stem cell treatment on mTOR and p-mTOR expression in ovarian damage due to cyclophosphomide	8
Independent and interaction effects of prenatal exposure to high AQI and extreme Humidex on the risk of preterm birth: A large sample population study in northern China	8
Transgenerational effects of bisphenol A on zebrafish reproductive tissues and sperm motility	8
Prenatal high-sucrose diet affects pulmonary artery contractile functions via MT receptors	8
Editorial Board	8
Effect of 1-nitropyrene exposure on the biological behavior of trophoblast cells	8
Intergenerational effects of the antioxidant Idebenone on the placentas of rats with gestational diabetes mellitus	8
Editorial Board	8
New approach methodologies to confirm developmental toxicity of pharmaceuticals based on weight of evidence	8
Neuropsychiatric outcomes in offspring after fetal exposure to maternal influenza infection during pregnancy: A systematic review	8
Bisphenol analogs AF, S and F: Effects on functional characteristics of porcine granulosa cells	8
In vivo pharmacokinetic analyses of placental transfer of three drugs of different physicochemical properties in pregnant rats	8
The mediating role of abnormal ZEB1 methylation in the association between nickel exposure and non-syndromic orofacial cleft	8
Role of Rab proteins in PFOA-induced changes in boar sperm motility and capacitation	8
Hormonal mechanism and pathogenetic therapy of citalopram-induced infertility in female rats	8
Biological sex differences in hepatic response to in utero dimethylbenz(a)anthracene exposure	8
Phthalates and polycystic ovary syndrome – Systematic literature review	7
Metal(loid)s and human semen quality: The LIFE Study	7
Ulipristal (UPA) effects on rat ovaries: Unraveling follicle dynamics, ovulation inhibition, and safety implications for prolonged use	7
Synthetic human gonadal tissues for toxicology	7
Effects of oridonin on sperm function and the PI3K/PDK1/AKT signaling pathway: Implications for reproductive toxicity	7
Subacute tributyltin exposure alters the development and morphology of mammary glands in association with CYP19A1 expression in female rats	7
Editorial Board	7
The fate of bisphenol A, bisphenol S, and their respective glucuronide metabolites in ovarian cells	7
Effectiveness of Withania frutescens root extract on testicular damage induced by lead acetate in adult albino rats	7
Association between menopausal age and smoking status defined using urinary cotinine or tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol: The Korea National Health	7
An analysis of birth defects and developmental disabilities for children of participants of the Air Force Health Study	7
Development of a microfluidic system structured on a modified polydimethylsiloxane device for the selection of bovine epididymal spermatozoa	7
Screening for chemicals with thyroid hormone-disrupting effects using zebrafish embryo	7
Vulnerable periods for the mouse mammary gland: Comparison of the effects of ethinyl estradiol exposures during two early stages of development	7
Exposure to Valproic acid (VPA) resulted in alterations in the expression of angiogenic genes (NRP-1, VEGFA, VEGFR-2 and sFlt1) and histological modifications in the placenta of mice (Mus musculus)	7
Corrigendum to “Peroxisome proliferator activated receptor gamma (PPAR-γ) ligand pioglitazone regulated gene networks in term human primary trophoblast cells” [Reprod. Toxicol. 81 (2018) 99–107]	7
Ampligo® 150 ZC affect the expression of sex hormone receptors and cell proliferation marker in female rabbit ovary: Protective effects of thyme essential oil and vitamin C	7
Sucralose triggers insulin resistance leading to follicular dysplasia in mice	7
Alkali and alkaline earth elements in maternal serum and occurrence of orofacial clefts in offspring	7
Transcriptional profiling of Chinese hamster ovary (CHO) cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)	7
1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal exposure induces testicular toxicity in male mice	6

Identification of endocrine disrupting chemicals targeting NTD-related hub genes during pregnancy via in silico analysis	6
Prenatal exposure to corn oil, CMC-Na or DMSO affects physical development and multi-organ functions in fetal mice	6
Use of leflunomide among girls and women of childbearing age and occurrence of leflunomide-exposed pregnancies in Germany	6
Associations between the proliferation of palatal mesenchymal cells, Tgfβ2 promoter methylation, Meg3 expression, and Smad signaling in atRA-induced cleft palate	6
AKT/mTOR-mediated autophagic signaling is associated with TCDD-induced cleft palate	6
Nicotinamide mononucleotide enhances the developmental potential of mouse early embryos exposed to perfluorooctanoic acid	6
Maternal dietary intake among alcohol-exposed pregnancies is linked to early infant physical outcomes in South Africa	6
Bisphenol M inhibits mouse oocyte maturation in vitro by disrupting cytoskeleton architecture and cell cycle processes	6
Editorial Board	6
Blastocyst exposure to plastic during mice in vitro fertilization impacts placental development	6
Upscaling biological complexity to boost neuronal and oligodendroglia maturation and improve in vitro developmental neurotoxicity (DNT) evaluation	6
Ultra-diluted/dynamized doxorubicin reduces the toxicity caused by doxorubicin during the in vitro culture of pig preantral follicles enclosed in ovarian tissue	6
Toxicity of cerium oxide nanoparticles on neonatal testicular development in mouse organ culture	6
TERT's protective effect on trophoblast cells: Reducing mitochondrial ROS	6
Pubertal sexual development and endpoints for disrupted spermatogenesis in the model Xenopus tropicalis	6
Endocrine disruptors and endometriosis	6
Evaluation of the maternal and developmental toxicity of 6-methylmercaptopurine riboside in rats	6
Effect of ofatumumab on pregnancy, parturition, and lactation in cynomolgus monkeys	6
The associations between prenatal plastic phthalate exposure and lipid acylcarnitine levels in humans and mice	6
Protective effect of Chlorella vulgaris on testicular damage, sperm parameters, androgen production, apoptosis and oxidative stress index in male rats following doxorubicin administration	6
Subacute exposure to a mixture of tributyltin plus mercury impairs reproductive axis function, exacerbating premature ovarian insufficiency features and reducing fertility in female rats	6
Characterization of pregnancies exposed to St. John’s wort and their outcomes: A claims data analysis	6
Alcohol induces p53-mediated apoptosis in neural crest by stimulating an AMPK-mediated suppression of TORC1, S6K, and ribosomal biogenesis	6
Perinatal fluoxetine dose-dependently affects prenatal stress-induced neurobehavioural abnormalities, HPA-axis functioning and underlying brain alterations in rat dams and their offspring	6
Lack of direct bone effect of tofacitinib, a JAK inhibitor, in juvenile rats and evaluation of the association between offspring growth and femur length	6
Smoking during pregnancy is associated with the placental proteome	6