Toxicology in Vitro

Article	Citations
Uptake and cellular effects of PE, PP, PET and PVC microplastic particles	97
Epigenetic toxicity of PFOA and GenX in HepG2 cells and their role in lipid metabolism	62
Folate conjugated hyaluronic acid coated alginate nanogels encapsulated oxaliplatin enhance antitumor and apoptosis efficacy on colorectal cancer cells (HT29 cell line)	61
Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models	60
Microfluidic chip for culturing intestinal epithelial cell layers: Characterization and comparison of drug transport between dynamic and static models	45
Cr(VI) induces ROS-mediated mitochondrial-dependent apoptosis in neuronal cells via the activation of Akt/ERK/AMPK signaling pathway	42
Antitumor activity of luteolin in human colon cancer SW620 cells is mediated by the ERK/FOXO3a signaling pathway	39
An integrated chemical environment with tools for chemical safety testing	38
Glutathione-responsive cyclodextrin-nanosponges as drug delivery systems for doxorubicin: Evaluation of toxicity and transport mechanisms in the liver	37
Rutin loaded liquid crystalline nanoparticles inhibit lipopolysaccharide induced oxidative stress and apoptosis in bronchial epithelial cells in vitro	36
Cytotoxic and cytocompatible comparison among seven photoinitiators-triggered polymers in different tissue cells	36
In vitro toxicity assessment of crosslinking agents used in hyaluronic acid dermal filler	35
Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-κB and activates Nrf2 in pancreatic cancer cells	34
Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids	33
Trigonelline inhibits Nrf2 via EGFR signalling pathway and augments efficacy of Cisplatin and Etoposide in NSCLC cells	33
Cellular uptake and toxicity of gold nanoparticles on two distinct hepatic cell models	30
A comparative in vitro toxicity assessment of electronic vaping product e-liquids and aerosols with tobacco cigarette smoke	30
PINK1/Parkin-mediated mitophagy is involved in NaAsO2-induced apoptosis of human hepatic cells through activation of ERK signaling	29
Secondary toxic effect of graphene oxide and graphene quantum dots alters the expression of miR-21 and miR-29a in human cell lines	28
Microplastics and nanoplastics: Size, surface and dispersant – What causes the effect?	28
Rosmarinic acid protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity in zebrafish embryos	27
Comparative evaluation of HET-CAM and ICE methods for objective assessment of ocular irritation caused by selected pesticide products	26
Inter-laboratory variability of A549 epithelial cells grown under submerged and air-liquid interface conditions	26
Application of ToxCast/Tox21 data for toxicity mechanism-based evaluation and prioritization of environmental chemicals: Perspective and limitations	25
Bisphenol A induces focal adhesions assembly and activation of FAK, Src and ERK2 via GPER in MDA-MB-231 breast cancer cells	25

CdTe and CdTe@ZnS quantum dots induce IL-1ß-mediated inflammation and pyroptosis in microglia	25
Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract	24
Comparative toxicity of ultrafine particles around a major airport in human bronchial epithelial (Calu-3) cell model at the air–liquid interface	24
Development of novel in silico prediction model for drug-induced ototoxicity by using naïve Bayes classifier approach	23
Trastuzumab-induced cardiotoxicity and role of mitochondrial connexin43 in the adaptive response	22
In vitro models of exosome biology and toxicology: New frontiers in biomedical research	22
Calycosin induces mitochondrial-dependent apoptosis and cell cycle arrest, and inhibits cell migration through a ROS-mediated signaling pathway in HepG2 hepatocellular carcinoma cells	21
E-cigarettes induce toxicity comparable to tobacco cigarettes in airway epithelium from patients with COPD	21
In vitro cytotoxicity of zinc oxide nanoparticles in mouse ovarian germ cells	21
Cytotoxic and proapoptotic effect of doxycycline – An in vitro study on the human skin melanoma cells	20
In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase	20
Calcium channel blockers lercanidipine and amlodipine inhibit YY1/ERK/TGF-β mediated transcription and sensitize the gastric cancer cells to doxorubicin	20
Perfluorooctane sulfonate induced toxicity in embryonic stem cell-derived cardiomyocytes via inhibiting autophagy-lysosome pathway	20
Potential application of two cobalt (III) Schiff base complexes in cancer chemotherapy: Leads from a study using breast and lung cancer cells	20
Differences in cytotoxicity of lung epithelial cells exposed to titanium dioxide nanofibers and nanoparticles: Comparison of air-liquid interface and submerged cell cultures	19
Differential influences of the BPA, BPS and BPF on in vitro IL-17 secretion by mouse and human T cells	19
Radiation-induced H3K9 methylation on E-cadherin promoter mediated by ROS/Snail axis : Role of G9a signaling during lung epithelial-mesenchymal transition	19
Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates	19
Prooxidative activity of plumbagin induces apoptosis in human pancreatic ductal adenocarcinoma cells via intrinsic apoptotic pathway	19
MAPK14 (p38α) inhibition effects against metastatic gastric cancer cells: A potential biomarker and pharmacological target	19
Piperlongumine induces apoptosis and G2/M phase arrest in human osteosarcoma cells by regulating ROS/PI3K/Akt pathway	18
Design, synthesis and biological evaluation of novel 1,2,3-triazole analogues of Imidazo-[1,2-a]-pyridine-3-carboxamide against Mycobacterium tuberculosis	18
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells	18
In vitro evaluation of the hepatic lipid accumulation of bisphenol analogs: A high-content screening assay	18
Activation of NLRP3 inflammasome in hepatocytes after exposure to cobalt nanoparticles: The role of oxidative stress	18
Assessment of intestinal absorption/metabolism of 3-chloro-1,2-propanediol (3-MCPD) and three 3-MCPD monoesters by Caco-2 cells	18
Extrapolating from acute to chronic toxicity in vitro	18
Lysophosphatidylcholine induces apoptosis and inflammatory damage in brain microvascular endothelial cells via GPR4-mediated NLRP3 inflammasome activation	18
Resveratrol protects against ethanol-induced impairment of insulin secretion in INS-1 cells through SIRT1-UCP2 axis	18
Melatonin prevents blood-retinal barrier breakdown and mitochondrial dysfunction in high glucose and hypoxia-induced in vitro diabetic macular edema model	18
Benzophenone-3 and benzophenone-8 exhibit obesogenic activity via peroxisome proliferator-activated receptor γ pathway	17
Development of a 96-well based assay for kinetic determination of catalase enzymatic-activity in biological samples	17
Environmental dose of 16 priority-controlled PAHs mixture induce damages of vascular endothelial cells involved in oxidative stress and inflammation	17
Human ileal organoid model recapitulates clinical incidence of diarrhea associated with small molecule drugs	17
Combined cytotoxic and genotoxic effects of ochratoxin A and fumonisin B1 in human kidney and liver cell models	16
Suppressing growth, migration, and invasion of human hepatocellular carcinoma HepG2 cells by Catharanthus roseus‑silver nanoparticles	16
Silibinin inhibits ethanol- or acetaldehyde-induced ferroptosis in liver cell lines	16
An engineered non-erythropoietic erythropoietin-derived peptide, ARA290, attenuates doxorubicin induced genotoxicity and oxidative stress	16
Anti-melanoma potential of two benzoquinone homologues embelin and rapanone - a comparative in vitro study	16
Investigation of nanoplastic cytotoxicity using SH-SY5Y human neuroblastoma cells and polystyrene nanoparticles	15
Comparative analysis of the impact of e-cigarette vapor and cigarette smoke on human gingival fibroblasts	15
The impact of synthetic amorphous silica (E 551) on differentiated Caco-2 cells, a model for the human intestinal epithelium	15
Tetramethylpyrazine alleviates iron overload damage in vascular endothelium via upregulating DDAHII expression	15
Effects of pulse-modulated radiofrequency magnetic field (RF-EMF) exposure on apoptosis, autophagy, oxidative stress and electron chain transport function in human neuroblastoma and murine microglial	15
Evaluation of oxindole derivatives as a potential anticancer agent against breast carcinoma cells: In vitro, in silico, and molecular docking study	15
Toxicological analysis of aerosols derived from three electronic nicotine delivery systems using normal human bronchial epithelial cells	15
Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis	15
Curcumin induces autophagic cell death in human thyroid cancer cells	15
Ophiopogonin D suppresses TGF-β1-mediated metastatic behavior of MDA-MB-231 breast carcinoma cells via regulating ITGB1/FAK/Src/AKT/β-catenin/MMP-9 signaling axis	15
TET-mediated DNA demethylation plays an important role in arsenic-induced HBE cells oxidative stress via regulating promoter methylation of OGG1 and GSTP1	14

Enhanced predictive capacity using dual-parameter chip model that simulates physiological skin irritation	14
Ciliary beat frequency of in vitro human nasal epithelium measured with the simple high-speed microscopy is applicable for safety studies of nasal drug formulations	14
Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action	14
Anticancer effects of non-steroidal anti-inflammatory drugs against cancer cells and cancer stem cells	14
Evaluation of in vitro models of stem cell-derived cardiomyocytes to screen for potential cardiotoxicity of chemicals	14
Low-concentration exposure to organochlorine pesticides (OCPs) in L6 myotubes and RIN-m5F pancreatic beta cells induces disorders of glucose metabolism	14
Chelerythrine hydrochloride inhibits proliferation and induces mitochondrial apoptosis in cervical cancer cells via PI3K/BAD signaling pathway	14
Bifenthrin insecticide promotes oxidative stress and increases inflammatory mediators in human neuroblastoma cells through NF-kappaB pathway	14
Cryopreservation affected the levels of immune responses of PBMCs and antigen-presenting cells	14
Monolayer (2D) or spheroids (3D) cell cultures for nanotoxicological studies? Comparison of cytotoxicity and cell internalization of nanoparticles	14
In silico prediction of chemical acute contact toxicity on honey bees via machine learning methods	14
Identifying adipogenic chemicals: Disparate effects in 3T3-L1, OP9 and primary mesenchymal multipotent cell models	13
Host microbiota dictates the proinflammatory impact of LPS in the murine liver	13
MiR-486-5p-directed MAGI1/Rap1/RASSF5 signaling pathway contributes to hydroquinone-induced inhibition of erythroid differentiation in K562 cells	13
Bioallethrin-induced generation of reactive species and oxidative damage in isolated human erythrocytes	13
Non-oxidative ethanol metabolism in human hepatic cells in vitro: Involvement of uridine diphospho-glucuronosyltransferase 1A9 in ethylglucuronide production	13
Comparison of the different protocols of the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) by evaluating the eye irritation potential of surfactants	13
In vitro protective effects of marine-derived Aspergillus puulaauensis TM124-S4 extract on H2O2-stressed primary human fibroblasts	13
The role and regulatory mechanism of autophagy in hippocampal nerve cells of piglet damaged by deoxynivalenol	13
Disintegrins extracted from totonacan rattlesnake (Crotalus totonacus) venom and their anti-adhesive and anti-migration effects on MDA-MB-231 and HMEC-1 cells	13
In vitro testing strategy for assessing the skin sensitizing potential of “difficult to test” cosmetic ingredients	13
An evaluation of a new high-sensitivity PrestoBlue assay for measuring cell viability and drug cytotoxicity using EA.hy926 endothelial cells	12
Investigation of molecular mechanisms underlying the antiproliferative effects of colchicine against PC3 prostate cancer cells	12
Mechanisms of peripheral neurotoxicity associated with four chemotherapy drugs using human induced pluripotent stem cell-derived peripheral neurons	12
Skin permeation of nickel, cobalt and chromium salts in ex vivo human skin, visualized using mass spectrometry imaging	12
In vitro toxicological evaluation of a tobacco heating product THP COO and 3R4F research reference cigarette on human lung cancer cells	12
Cytotoxic and genotoxic assessments of 2,4-dichlorophenoxyacetic acid (2,4-D) in in vitro mammalian cells	12
Molecular fingerprints of conazoles via functional genomic profiling of	12
Application of QSARs in identification of mutagenicity mechanisms of nitro and amino aromatic compounds against Salmonella typhimurium species	12
Acrylamide and its metabolite induce neurotoxicity via modulation of protein kinase C and AMP-activated protein kinase pathways	12
Circular RNA PVT1 inhibits tendon stem/progenitor cell senescence by sponging microRNA-199a-5p	12
Combined SRPK and AKT pharmacological inhibition is synergistic in T-cell acute lymphoblastic leukemia cells	12
Paraquat-activated BV-2 microglia induces neuroinflammatory responses in the neuron model through NF-κB signaling pathway	12
A novel synergistic anticancer effect of fungal cholestanol glucoside and paclitaxel: Apoptosis induced by an intrinsic pathway through ROS generation in cervical cancer cell line (HeLa)	12
Cigarette smoke and glutathione: Focus on in vitro cell models	12
Nimbolide-encapsulated PLGA nanoparticles induces Mesenchymal-to-Epithelial Transition by dual inhibition of AKT and mTOR in pancreatic cancer stem cells	12
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis	12
Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells	11
The role of MITF and Mcl-1 proteins in the antiproliferative and proapoptotic effect of ciprofloxacin in amelanotic melanoma cells: In silico and in vitro study	11
Physiologically relevant oxygen tensions differentially regulate hepatotoxic responses in HepG2 cells	11
Hypoxia/reoxygenation exacerbates drug-induced cytotoxicity by opening mitochondrial permeability transition pore: Possible application for toxicity screening	11
Effects of vanadium (sodium metavanadate) and aflatoxin-B1 on cytochrome p450 activities, DNA damage and DNA methylation in human liver cell lines	11
Novel diphenyl urea derivative serves as an inhibitor on human lung cancer cell migration by disrupting EMT via Wnt/β-catenin and PI3K/Akt signaling	11
Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells	11
Bioavailability of hydrophobic organic chemicals on an in vitro metabolic transformation using rat liver S9 fraction	11
Arsenic-induced autophagy regulates apoptosis in AML-12 cells	11
Uranium induces genomic instability and slows cell cycle progression in human lymphocytes in acute toxicity study	11
Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells	11
Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug	11
p53-mediated ferroptosis is required for 1-methyl-4-phenylpyridinium-induced senescence of PC12 cells	11
Evaluation of the genotoxic, DNA-protective and antioxidant profile of synthetic alkyl gallates and gallotannins using in vitro assays	11
Mogroside V exerts anti-inflammatory effects on fine particulate matter-induced inflammation in porcine alveolar macrophages	11
Underlying mechanisms of cytotoxicity in HepG2 hepatocarcinoma cells exposed to arsenic, cadmium and mercury individually and in combination	11
Nanolipid-loaded Preyssler polyoxometalate: Synthesis, characterization and invitro inhibitory effects on HepG2 tumor cells	11
Cadmium induces cell growth in A549 and HELF cells via autophagy-dependent glycolysis	11
MiR-429/200a/200b negatively regulate Notch1 signaling pathway to suppress CoCl2-induced apoptosis in PC12 cells	11
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat	11
In vitro genotoxicity assessment of monopotassium glutamate and magnesium diglutamate	11
Antimycin A-induced mitochondrial dysfunction is consistent with impaired insulin signaling in cultured skeletal muscle cells	11
E-cigarette fluids and aerosol residues cause oxidative stress and an inflammatory response in human keratinocytes and 3D skin models	11
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets	11
Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound	10
Mutagenicity evaluation of pesticide analogs using standard and 6-well miniaturized bacterial reverse mutation tests	10
Mitochondrial dysfunction and apoptosis underlie the hepatotoxicity of perhexiline	10
Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals	10
Scutellarin attenuates doxorubicin-induced oxidative stress, DNA damage, mitochondrial dysfunction, apoptosis and autophagy in H9c2 cells, cardiac fibroblasts and HUVECs	10
Developmental toxicity testing of unsubstituted and methylated 4- and 5-ring polycyclic aromatic hydrocarbons using the zebrafish embryotoxicity test	10
Synthesis and characterization of modified magnetic nanoparticles as theranostic agents: in vitro safety assessment in healthy cells	10
Transcriptomic and proteomic responses of silver nanoparticles in hepatocyte-like cells derived from human induced pluripotent stem cells	10
Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods	10
High-content imaging of 3D-cultured neural stem cells on a 384-pillar plate for the assessment of cytotoxicity	10
Dissolution of titanium dioxide nanoparticles in synthetic biological and environmental media to predict their biodurability and persistence	10
Applying knowledge-driven mechanistic inference to toxicogenomics	10
Oxidative stress as an underlying mechanism of anticancer drugs cytotoxicity on human red blood cells' membrane	10
Characterization of prodigiosin pigment by Serratia marcescens and the evaluation of its bioactivities	10
A quantitative AOP of mitochondrial toxicity based on data from three cell lines	10
Next generation risk assessment (NGRA): Bridging in vitro points-of-departure to human safety assessment using physiologically-based kinetic (PBK) modelling – A case study of doxorubicin with dose met	10
In vitro and bioinformatics mechanistic-based approach for cadmium carcinogenicity understanding	10
Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach	10
An analysis of mitotic catastrophe induced cell responses in melanoma cells exposed to flubendazole	10

Investigating dihydroorotate dehydrogenase inhibitor mediated mitochondrial dysfunction in hepatic in vitro models	10
Voacamine: Alkaloid with its essential dimeric units to reverse tumor multidrug resistance	10
Comparative γ-H2AX analysis for assessment of the genotoxicity of six aromatic amines implicated in bladder cancer in human urothelial cell line	10
Pendulone induces apoptosis via the ROS-mediated ER-stress pathway in human non-small cell lung cancer cells	10
Responses of increasingly complex intestinal epithelium in vitro models to bacterial toll-like receptor agonists	9
Chronic and acute arsenic exposure enhance EGFR expression via distinct molecular mechanisms	9
Temporal transcriptomic alterations of cadmium exposed human iPSC-derived renal proximal tubule-like cells	9
Novel benzoate-lipophilic cations selectively induce cell death in human colorectal cancer cell lines	9
MicroRNA-106b-5p participates in lead (Pb2+)-induced cell viability inhibition by targeting XIAP in HT-22 and PC12 cells	9
Oligomycin-induced proton uncoupling	9
The dissolution of stone wool fibers with sugar-based binder and oil in different synthetic lung fluids	9
Toxicological impact of organic ultrafine particles (UFPs) in human bronchial epithelial BEAS-2B cells at air-liquid interface	9
Limonene-carvacrol: A combination of monoterpenes with enhanced antileishmanial activity	9
The selected epigenetic effects of aminomethylphosphonic acid, a primary metabolite of glyphosate on human peripheral blood mononuclear cells (in vitro)	9
An in vitro model for microbial fructoselysine degradation shows substantial interindividual differences in metabolic capacities of human fecal slurries	9
Comparative study of cytotoxicity by platinum nanoparticles and ions in vitro systems based on fish cell lines	9
Cytotoxicity of cobalt chloride in brain cell lines - a comparison between astrocytoma and neuroblastoma cells	9
Development of the SkinEthic HCE Time-to-Toxicity test method for identifying liquid chemicals not requiring classification and labelling and liquids inducing serious eye damage and eye irritation	9
Lapachol acetylglycosylation enhances its cytotoxic and pro-apoptotic activities in HL60 cells	9
Silica nanoparticle induces pulmonary fibroblast transdifferentiation via macrophage route: Potential mechanism revealed by proteomic analysis	9
Cell-based high-throughput screening for the evaluation of reactive metabolite formation potential	9
Cigarette smoke extracts induce apoptosis in Raw264.7 cells via endoplasmic reticulum stress and the intracellular Ca2+/P38/STAT1 pathway	9
Novel podophyllotoxin and benzothiazole derivative induces transitional morphological and functional changes in HaCaT cells	9
An international validation study of the IL-2 Luc assay for evaluating the potential immunotoxic effects of chemicals on T cells and a proposal for reference data for immunotoxic chemicals	9
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes	9
Skin penetration and decontamination efficacy following human skin exposure to fentanyl	9
Persistent endocrine-disrupting chemicals found in human follicular fluid stimulate IGF1 secretion by adult ovarian granulosa cell tumor spheroids and thereby increase proliferation of non-cancer ovar	9
The predictivity of the -alert performance- functionality of the OECD QSAR-Toolbox (c/w further issues on the predictivity of nonclinical testing)	9
Natural triterpenoid saponin Momordin Ic suppresses HepG2 cell invasion via COX-2 inhibition and PPARγ activation	9
Curcumin analog, WZ37, promotes G2/M arrest and apoptosis of HNSCC cells through Akt/mTOR inhibition	9
Assessment of the in vitro developmental toxicity of diethylstilbestrol and estradiol in the zebrafish embryotoxicity test	9
Exploration of xenobiotic metabolism within cell lines used for Tox21 chemical screening	9
Cigarette smoke promotes chronic obstructive pulmonary disease (COPD) through the miR-130a/Wnt1 axis	9
Effect of silibinin on ethanol- or acetaldehyde-induced damge of mouse primary hepatocytes in vitro	8
Time dependent impact of copper oxide nanomaterials on the expression of genes associated with oxidative stress, metal binding, inflammation and mucus secretion in single and co-culture intestinal in	8
Comparative analysis of biological effects of molybdenum(IV) sulfide in the form of nano- and microparticles on human hepatoma HepG2 cells grown in 2D and 3D models	8
The numerical probability of carcinogenicity to humans of some antimicrobials: Nitro-monoaromatics (including 5-nitrofurans and 5-nitroimidazoles), quinoxaline-1,4-dioxides (including carbadox), and c	8
Standardized pyrogen testing of medical products with the bacterial endotoxin test (BET) as a substitute for rabbit Pyrogen testing (RPT): A scoping review	8
The role of UVA radiation in ketoprofen-mediated BRAF-mutant amelanotic melanoma cells death – A study at the cellular and molecular level	8
Triclosan affects the expression of nitric oxide synthases (NOSs), peroxisome proliferator-activated receptor gamma (PPARγ), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)	8
2′-Hydroxyflavanone prevents LPS-induced inflammatory response and cytotoxicity in murine macrophages	8
Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment	8
Transcriptome sequencing of 3,3′,4,4′,5-Pentachlorobiphenyl (PCB126)-treated human preadipocytes demonstrates progressive changes in pathways associated with inflammation and diabetes.	8
Cytotoxicity comparison of 35 developmental neurotoxicants in human induced pluripotent stem cells (iPSC), iPSC-derived neural progenitor cells, and transformed cell lines	8
Maximizing the relevance and reproducibility of A549 cell culture using FBS-free media	8
Meta-analysis of in-vitro cytotoxicity evaluation studies of zinc oxide nanoparticles: Paving way for safer innovations	8
SkinEthic HCE Time-to-Toxicity on solids: A test method for distinguishing chemicals inducing serious eye damage, eye irritation and not requiring classification and labelling	8
Plumbagin downregulates UHRF1, p-Akt, MMP-2 and suppresses survival, growth and migration of cervical cancer CaSki cells	8
TGF-β1 decreases CHOP expression and prevents cardiac fibroblast apoptosis induced by endoplasmic reticulum stress	8
Altered molecular pathways decides the treatment outcome of Hsp90 inhibitors against breast cancer cells	8
Palmitate-induced toxicity is associated with impaired mitochondrial respiration and accelerated oxidative stress in cultured cardiomyocytes: The critical role of coenzyme Q9/10	8
Hazard assessment using an in-silico toxicity assessment of the transformation products of boscalid, pyraclostrobin, fenbuconazole and glyphosate generated by exposure to an advanced oxidative process	8
Polyphenol effects on CuO-nanoparticle-mediated DNA damage, reactive oxygen species generation, and fibroblast cell death	8
Emerging trends in immunotoxin targeting cancer stem cells	8
Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures	8
Recent advancements and application of in vitro models for predicting inhalation toxicity in humans	8
Validation study of a new reconstructed human epidermis model EPiTRI for in vitro skin irritation test according to OECD guidelines	8
Hydroxylation markedly alters how the polychlorinated biphenyl (PCB) congener, PCB52, affects gene expression in human preadipocytes	8
Microcystin-LR-induced autophagy regulates oxidative stress, inflammation, and apoptosis in grass carp ovary cells in vitro	8
Comparison of passive-dosed and solvent spiked exposures of pro-carcinogen, benzo[a]pyrene, to human lymphoblastoid cell line, MCL-5	8