Toxicology in Vitro

Papers
(The median citation count of Toxicology in Vitro is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Editorial Board80
Evaluation of an imaging-based in vitro screening platform for estrogenic activity with OECD reference chemicals55
In vitro safety evaluation of sunscreen formulation from nanostructured lipid carriers using human cells and skin model44
Increased effects of 2,5-dimethylcelecoxib on sensitivity of hepatocellular carcinoma cells to sorafenib via CYP3A5 expression and activation of AMPK36
Gellan gum hydrogels cross-linked with carbodiimide stimulates vacuolation of human tooth-derived stem cells in vitro35
The selected epigenetic effects of phthalates: DBP, BBP and their metabolites: MBP, MBzP on human peripheral blood mononuclear cells (In Vitro)30
Using cimetidine to mitigate cisplatin-induced ototoxicity29
Essential oil from Ocimum carnosum induces ROS mediated mitochondrial dysfunction and intrinsic apoptosis in HL-60 cells28
Emerging trends in immunotoxin targeting cancer stem cells28
Mechanism for inhibition of cytotoxicity of Shiga toxin by luteolin27
Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array27
Prediction of acute oral toxicity using the Hansen solubility parameter26
Organochlorine pesticides disrupt T helper cell regulation and reduce IL-2 and IFN-γ favoring infection and production of autoantibodies among pemphigus patients26
Evaluation of in vitro cornea models for quantifying destructive effects of chemicals26
Metformin and buparlisib synergistically induce apoptosis of non-small lung cancer (NSCLC) cells via Akt/FoxO3a/Puma axis25
Construction of an in vitro simulated one compartment extravascular administration model and its comparison with classic in vitro administration model in copper chloride induced HepG2 cell death25
Dinaciclib inhibits the growth of acute myeloid leukemia cells through either cell cycle-related or ERK1/STAT3/MYC pathways24
In-house performance assessment of 3D QobuR-Reconstructed Human Cornea-Like Epithelium (RhCE) for the evaluation of eye hazard23
Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol23
Protective effects of silibinin against ethanol- or acetaldehyde-caused damage in liver cell lines involve the repression of mitochondrial fission23
The evaluation of anticancer activity by synthesizing 5FU loaded albumin nanoparticles by exposure to UV light22
In vitro genotoxic and antigenotoxic effects of an exopolysaccharide isolated from Lactobacillus salivarius KC27L21
Corrigendum to ‘Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach’ [Toxicology in Vitro 68 (2020) 104952]20
Comparative analyses of transcriptome sequencing and carcinogenic exposure toxicity of nicotine and 6-methyl nicotine in human bronchial epithelial cells20
Multidirectional anti-melanoma effect of galactolipids (MGDG-1 and DGDG-1) from Impatiens parviflora DC. and their synergy with doxorubicin20
Benzo[b]fluoranthene (B[b]F) affects apoptosis, oxidative stress, mitochondrial membrane potential and expressions of blood-brain barrier markers in microvascular endothelial cells20
Antimycin A-induced mitochondrial dysfunction is consistent with impaired insulin signaling in cultured skeletal muscle cells19
Machine learning predictive classification models for the carcinogenic activity of activated metabolites derived from aromatic amines and nitroaromatics19
A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells19
Cytotoxicity reduction by O-nicotinoylation of antiviral 6-benzylaminopurine ribonucleosides19
An in vitro nerve agent brain poisoning transwell model for convenient and accurate antidote evaluation19
Nimbolide-encapsulated PLGA nanoparticles induces Mesenchymal-to-Epithelial Transition by dual inhibition of AKT and mTOR in pancreatic cancer stem cells18
Development of a human FaFg prediction system for polyphenols using human induced pluripotent stem cell-derived small intestinal epithelial cells18
Physodic acid sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis18
Influence of bile acids on the cytotoxicity of chemicals in cultivated human hepatocytes18
Phloretin exhibits potential food-drug interactions by inhibiting human UDP-glucuronosyltransferases in vitro18
Anti-migratory and cytotoxic effect of indole derivative in C6 glioma cells17
Editorial Board17
Analysis of reproducibility and robustness of OrganoPlate® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs17
Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells17
TGF-β1/SMADs signaling involved in alleviating inflammation induced by nanoparticulate titanium dioxide in BV2 cells17
Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system17
Assessment of the utility of the novel Phenion® full thickness human skin model for detecting the skin irritation potential of antimicrobial cleaning products17
Sinapic acid alleviates glutamate-induced excitotoxicity by inhibiting neuroinflammation and endoplasmic reticulum stress pathway in C6 glioma cells17
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes16
Sens-ocular model: Cell-based assay to evaluate eye stinging potential of chemicals and baby cosmetic formulations.16
The effect of endocrine disrupting chemicals on the vitronectin-receptor (integrin αvβ3)-mediated cell adhesion of human umbilical vein endothelial cells16
Can TK-TD modelling bridge the gap between in vitro and in vivo mammalian toxicity data?16
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells16
Silencing Nrf2 in cisplatin resistant non-small cell lung cancer cells augments sensitivity towards EGFR inhibitor16
Streptomycin generates oxidative stress in melanin-producing cells: In vitro study with EPR spectroscopy evidence16
Editorial Board15
Curcumin induces mitophagy by promoting mitochondrial succinate dehydrogenase activity and sensitizes human papillary thyroid carcinoma BCPAP cells to radioiodine treatment15
Editorial Board15
Development of natural cosmetic emulsion using the by-product of Lecythis pisonis seed15
Effects of radical scavengers for reactive oxygen species on vitamin K-induced phototoxicity under UVA irradiation15
The importance of metrological tools to implementation of alternative method OECD TG 42815
Influence of alkylthio and arylthio derivatives of tert-butylquinone on the induction of DNA damage in a human hepatocellular carcinoma cell line (HepG2)15
In vitro immune and redox response induced by cationic cellulose-based nanomaterials14
Selective inhibition of HDAC6 by N-acylhydrazone derivative reduces the proliferation and induces senescence in carcinoma hepatocellular cells14
Photodynamic therapy with curcumin and near-infrared radiation as an antitumor strategy to glioblastoma cells14
In vitro inhibitory effects of selumetinib on activity of human UDP-glucuronosyltransferases and prediction of in vivo drug-drug interactions14
Calcium channel blockers lercanidipine and amlodipine inhibit YY1/ERK/TGF-β mediated transcription and sensitize the gastric cancer cells to doxorubicin14
Overdose with the anesthetic propofol causes hematological cytotoxicity and immune cell alteration in an experimental ex vivo whole blood culture model14
Studying the intracellular bile acid concentration and toxicity in drug-induced cholestasis: Comprehensive LC-MS/MS analysis with human liver slices14
Enhanced cell death effects of MAP kinase inhibitors in propyl gallate-treated lung cancer cells are related to increased ROS levels and GSH depletion14
Characterization of prodigiosin pigment by Serratia marcescens and the evaluation of its bioactivities13
Optimization of in vitro culture of honeybee nervous tissue for pesticide risk assessment13
Comprehensive studies on the biological activities of human metastatic (MDA-MB-231) and non-metastatic (MCF-7) breast cancer cell lines, directly or combinedly treated using non-thermal plasma-based a13
Developmental toxicity testing of unsubstituted and methylated 4- and 5-ring polycyclic aromatic hydrocarbons using the zebrafish embryotoxicity test13
ESTIV 2022: Key enabling non-animal technologies for research, education and testing13
The effects of Acyclovir administration to NCI-H1975 non-small cell lung cancer cells13
Characterization of elements, PAHs, AhR-activity and pro-inflammatory responses of road tunnel-derived particulate matter in human hepatocyte-like and bronchial epithelial cells13
Editorial Board13
Toxicological and microbiological characterization of cow stable dust13
A potential role of calpains in sulfonylureas (SUs) –mediated death of human pancreatic cancer cells (1.2B4)12
Differential comparison of genotoxic effects of aristolochic acid I and II in human cells by the mass spectroscopic quantification of γ-H2AX12
Cigarette smoke extract decreases human bone marrow mesenchymal stromal cell adipogenic differentiation12
In vitro assessment of cytotoxicity of spent fluid catalytic cracking refinery catalysts on cell lines and identification of critical toxic metals12
Butein induces intrinsic pathway of apoptosis, vimentin proteolysis, and inhibition of cancer stem cell population in a human papillary thyroid cancer cell line12
Editorial Board12
Nonylphenol reduced the number of haploids in in vitro spermatogenesis of the endangered cyprinid Gnathopogon caerulescens12
Organic ultraviolet filters regulate hyaluronan metabolism in human epidermal keratinocytes through the phosphatidylinositol 3-kinase pathway12
Effects of antimicrobial metal nanoparticles on characteristics and function properties of mouse mesenchymal stem cells12
Corrigendum to “Zearalenone causes embryotoxicity and induces oxidative stress and apoptosis in differentiated human embryonic stem cells” [Toxicology in Vitro 54 (2019) 243–250]12
Fragrances as a trigger of immune responses in different environments12
Silibinin inhibits ethanol- or acetaldehyde-induced ferroptosis in liver cell lines11
Investigation of molecular mechanisms underlying the antiproliferative effects of colchicine against PC3 prostate cancer cells11
How to use an in vitro approach to characterize the toxicity of airborne compounds11
Involvement of Sirt1-FoxO3a-Bnip3 axis and autophagy mediated mitochondrial turnover in according protection to hyperglycemic NRK-52E cells by Berberine11
The effect of airborne Palladium nanoparticles on human lung cells, endothelium and blood – A combinatory approach using three in vitro models11
TNF-α and MMPs mediated mucus hypersecretion induced by cigarette smoke: An in vitro study11
Corrigendum to ‘Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells’ [Toxicol In Vitro 59 (2019) 300–311]11
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level11
The numerical probability of carcinogenicity to humans of some antimicrobials: Nitro-monoaromatics (including 5-nitrofurans and 5-nitroimidazoles), quinoxaline-1,4-dioxides (including carbadox), and c11
Influence of cellular redox environment on aryl hydrocarbon receptor ligands induced melanogenesis10
Editorial Board10
Evaluating the QileX-RhE skin corrosion test for chemical subcategorization in accordance with OECD TG 43110
Stable expression of the human dopamine transporter in N27 cells as an in vitro model for dopamine cell trafficking and metabolism10
DNA damage response and apoptosis induced by hyperthermia in human umbilical cord blood lymphocytes10
Bufadienolides from the Bufo viridis toad venom exert cytotoxic effects on cancer cells by inducing cell apoptosis and cell cycle arrest10
4-O-methylascochlorin-stimulated HIF-1α expression induces the epithelial mesenchymal transition and cell survival in breast cancer cells10
Stent conditioned media for in vitro evaluation of hydrophobic stent coatings10
Transcription Factor yin-Yang 1 augments nucleoporin 93 oncogene activity and modulates bladder Cancer malignancy10
4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl110
Transdermal permeation of inorganic cerium salts in intact human skin10
Benzo[a]pyrene inhibits myoblast differentiation through downregulating the Hsp70-MK2-p38MAPK complex10
Frankenstein's followers. Maintenance of human cells outside the body. Issue 110
In vitro toxicity of two functionalized reduced graphene oxide materials with potential application in food packaging10
Intragenic antimicrobial peptide Hs02 toxicity against leukemia cell lines is associated with increased expression of select pyroptotic components10
Mesoporous nanosilica: A thromboprotective nanomaterial for biomedical applications10
N-acetyl-L-cysteine attenuated the toxicity of ZIF-8 on EA.hy926 endothelial cells by wnt/β-catenin pathway10
Risk assessment of chlorophenols (CPs) exposure in vitro:Inhibition of sulfotransferases (SULTs) activity9
Exosome proteomics study of the effects of traditional cigarettes and electronic cigarettes on human bronchial epithelial cells9
Acute cytotoxicity, genotoxicity, and apoptosis induced by petroleum VOC emissions in A549 cell line9
Mictlan-D3: A novel medium sized RGD-Disintegrin obtained from Crotalus mictlantecuhtli venom, in vitro tested against human breast Cancer and endothelial cells9
In silico modelling of acute toxicity of 1, 2, 4-triazole antifungal agents towards zebrafish (Danio rerio) embryos: Application of the Small Dataset Modeller tool9
Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals9
The SNHG10-miR-495-3p-PTEN axis is involved in sevoflurane-mediated protective effects in cardiomyocytes against hypoxia/reoxygenation injury9
Melatonin prevents blood-retinal barrier breakdown and mitochondrial dysfunction in high glucose and hypoxia-induced in vitro diabetic macular edema model9
Identification of the function and regulatory network of circ_009773 in DNA damage induced by nanoparticles of neodymium oxide9
Pracaxi oil affects xenobiotic metabolisms, cellular proliferation, and oxidative stress without cytotogenotoxic effects in HepG2/C3A cells9
Differential cytotoxic activity of pharmacological inhibitors of IGF1R-related pathways in JAK2V617F driven cells9
Acrylamide-induced damage to postsynaptic plasticity is CYP2E1 dependent in an SH-SY5Y co-culture system9
Biological effects of combustion-derived particles from different biomass sources on human bronchial epithelial cells9
Strategies for the evaluation of the eye irritation potential of different types of surfactants and silicones used in cosmetic products9
In vitro human skin absorption of ethyl salicylate, pentyl salicylate, and (Z)-3-hexenyl salicylate from topical formulations: Effects on permeation and distribution9
Risperidone-induced bioenergetic disruption in the isolated human peripheral blood monocytes9
Potential risk of drug-drug interactions of ponatinib via inhibition against human UDP-glucuronosyltransferases9
Everolimus prevents doxorubicin-induced apoptosis in H9c2 cardiomyocytes but not in MCF-7 cancer cells: Cardioprotective roles of autophagy, mitophagy, and AKT9
Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells8
Evaluation of toxicological aspects of three new benzoxazole compounds with sunscreen photophysical properties using in silico and in vitro methods8
Perfluorooctanoic acid inhibits cell proliferation through mitochondrial damage8
Risk assessment of the inhibition of hydroxygenkwanin on human and rat cytochrome P450 by cocktail method8
Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound8
Mettl3-mediated transcriptome-wide m6A methylation induced by cigarette smoking in human bronchial epithelial cells8
(-)-Epigallocatechin gallate as an inhibitor of hemoglobin-catalyzed lipid oxidation: molecular mechanism of action and nutritional application8
Investigating the mechanisms of action of thyroid disruptors: A multimodal approach that integrates in vitro and metabolomic analysis8
Polystyrene nanoparticles incorporate into the endoplasmic reticulum and disturb translation during meiotic maturation in mouse oocytes8
In vitro toxicological evaluation of a tobacco heating product THP COO and 3R4F research reference cigarette on human lung cancer cells8
Editorial Board8
In vitro metabolism of lidocaine in subcellular post-mitochondrial fractions and precision cut slices from cattle liver8
(3α)-3-(tiglinoyloxy)-ent-kaur-16-en-19-oic acid, isolated from Wedelia trilobata L., exerts an anti-inflammatory effect via the modulation of NF-κB, MAPK and mTOR pathway and autophagy in LPS-stimula8
6:2 fluorotelomer sulfonate as a safer alternative to PFOS: Comparative cytotoxicity and oxidative stress mechanisms in pancreatic β-cells (INS-1 model)8
Mitochondria oxidative stress mediated nicotine-promoted activation of pancreatic stellate cells by regulating mitochondrial dynamics8
Effects of di-(2-ethylhexyl) phthalate and its metabolites on transcriptional activity via human nuclear receptors and gene expression in HepaRG cells8
E-cigarette fluids and aerosol residues cause oxidative stress and an inflammatory response in human keratinocytes and 3D skin models8
Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR signaling pathway8
Study on percutaneous penetration of representative cosmetic ingredients in a baby wipe product in an in vitro diaper rash skin model8
Washing with buffered vitamin C after corrosive chemical (sodium hypochlorite) exposure reduces ocular depth of injury8
In vitro eye irritation testing models may play pivotal role in effort to pursue mild baby cleansers8
Comparative evaluation of HET-CAM and ICE methods for objective assessment of ocular irritation caused by selected pesticide products8
Effects of methylation of arginine residue 83 on the enzymatic activity of human arsenic (+3 oxidation state) methyltransferase8
Time dependent impact of copper oxide nanomaterials on the expression of genes associated with oxidative stress, metal binding, inflammation and mucus secretion in single and co-culture intestinal in 8
The role of efflux transporters in cytotoxicity and intracellular concentration of chlorpyrifos and chlorpyrifos oxon in human cell lines8
Delta-9 tetrahydrocannabinol (THC) effects on the cortisol stress response in bovine granulosa cells7
Chemometric modeling of acute toxicity of diverse aromatic compounds against Rana japonica7
A battery of in silico models application for pesticides exerting reproductive health effects: Assessment of performance and prioritization of mechanistic studies7
A novel O2- (2,4-dinitrophenyl) diazeniumdiolate inhibits hepatocellular carcinoma migration, invasion, and EMT through the Wnt/β-catenin pathway7
Dendritic cells activated by cimetidine induce Th1/Th17 polarization in vitro and in vivo7
Telomere loss is accompanied by decreased pool of shelterin proteins TRF2 and RAP1, elevated levels of TERRA and enhanced glycolysis in imatinib-resistant CML cells7
Toxicity of New Psychoactive Substance (NPS): Threo-4-methylmethylphenidate (4-Mmph) – Prediction of toxicity using in silico methods7
Busulfan-induced hepatic sinusoidal endothelial cell injury: Modulatory role of pirfenidone for therapeutic purposes7
Blocking Autophagy by the Two-Pore Channels Antagonist Tetrandrine Improves Sorafenib-Induced Death of Hepatocellular Carcinoma Cells7
Transcriptomic changes and mitochondrial toxicity in response to acute and repeat dose treatment with brequinar in human liver and kidney in vitro models7
STF-083010 an inhibitor of IRE1α endonuclease activity affects mitochondrial respiration and generation of mitochondrial membrane potential7
Cell differentiation in the cardiac embryonic stem cell test (ESTc) is influenced by the oxygen tension in its underlying embryonic stem cell culture7
m-Cresol,a pesticide intermediate, induces hepatotoxicity and behavioral abnormalities in zebrafish larvae through oxidative stress, apoptosis7
Long-term in vitro exposure of human granulosa cells to the mixture of endocrine disrupting chemicals found in human follicular fluid disrupts steroidogenesis7
In vitro biocompatibility and wound healing properties of latex proteins dressing7
Normalization of organ-on-a-Chip samples for mass spectrometry based proteomics and metabolomics via Dansylation-based assay7
Next generation risk assessment (NGRA): Bridging in vitro points-of-departure to human safety assessment using physiologically-based kinetic (PBK) modelling – A case study of doxorubicin with dose met7
Differential DNA damage response and cell fate in human lung cells after exposure to genotoxic compounds7
Editorial Board7
Pre-validation of a Calu-3 epithelium cytotoxicity assay for predicting acute inhalation toxicity of chemicals6
Triclosan affects the expression of nitric oxide synthases (NOSs), peroxisome proliferator-activated receptor gamma (PPARγ), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) 6
Chemotherapeutic effect of baicalein/epirubicin combination against liver cell carcinoma in-vitro: Inducing apoptosis and autophagy6
Triphenyltin chloride exposure inhibits meiotic maturation of mouse oocytes by disrupting cytoskeleton assembly and cell cycle progression6
Exploration of xenobiotic metabolism within cell lines used for Tox21 chemical screening6
Arsenic trioxide inhibits the response of primary human B cells to influenza virus A in vitro6
Effects of an environmentally relevant mixture of organochlorine pesticide compounds on adipogenesis and adipocyte function in an immortalized human adipocyte model6
Effect of long-term inorganic arsenic exposure on erythropoietin production in vitro6
Lead inhibits the odontogenic differentiation potential of dental pulp stem cells by affecting WNT1/β-catenin signaling and related miRNAs expression6
Cytotoxicity assay to assess eye irritation – A comparison with other methods and possible strategies for use6
Hydroxylation markedly alters how the polychlorinated biphenyl (PCB) congener, PCB52, affects gene expression in human preadipocytes6
Application of ToxCast/Tox21 data for toxicity mechanism-based evaluation and prioritization of environmental chemicals: Perspective and limitations6
Antifungal climbazole alters androgenic pathways in mammalian cells6
Suitability of human HepaRG cells and liver spheroids as in vitro model to investigate the bioactivation of the organothiophosphate pesticide parathion6
Interactions of oleanane pentacyclic triterpenoids with human organic anion transporting polypeptide 1B1 and 1B36
Effect of curcumin on the embryotoxic effect of ethanol in a zebrafish model6
Proton pump inhibitors interfere with the anti-tumor potency of RC48ADC6
Evaluation of the inhibitory effects of antigout drugs on human carboxylesterases in vitro6
miRNA-6515-5p regulates particulate matter-induced inflammatory responses by targeting CSF3 in human bronchial epithelial cells6
The mechanism of thrombocytopenia caused by cholesterol-conjugated antisense oligonucleotides6
The impact of bisphenol AF on skeletal muscle function and differentiation in vitro6
Curcumin-loaded emulsome nanoparticles induces apoptosis through p53 signaling pathway in pancreatic cancer cell line PANC-16
Development of 3D-QSAR models for predicting the activities of chemicals to stimulate muscle growth via β2-adrenoceptor6
METTL3 regulates FAM83D m6A modification to accelerate tumorigenesis of triple-negative breast cancer via the Wnt/β-catenin pathway6
Multi-label classification and label dependence in in silico toxicity prediction6
Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects6
USP18 mitigates lipopolysaccharide-induced oxidative stress and inflammation in human pulmonary microvascular endothelial cells through the TLR4/NF-κB/ROS signaling5
Effects of iron oxide nanoparticles on the gene expression profiles of cerebral endotheliocytes and astrocytes5
Counterions determine uptake and effects of aluminum in human intestinal and liver cells5
Cannabinoids and standardized cannabis extracts inhibit migration, invasion, and induce apoptosis in MCF-7 cells through FAK/MAPK/Akt/NF-κB signaling5
Suppression of lncRNA Snhg1 inhibits high glucose-induced inflammation and proliferation in mouse mesangial cells5
N-acetylcysteine protect inner hair cells from cisplatin by alleviated celluar oxidative stress and apoptosis5
Selected phytocannabinoids inhibit SN-38- and cytokine-evoked increases in epithelial permeability and improve intestinal barrier function in vitro5
Different cellular mechanism of imidacloprid and acetamiprid by a combined targeted lipidomics and metabolomics approach in Neuro-2a cells5
Engineering of gelatin scaffold by extracellular matrix of Sertoli cells for embryonic stem cell proliferation5
Clarify the potential cholestatic hepatotoxicity components from Chinese Herb Medicine and metabolism’s role via hBSEP vesicles and S9/hBSEP vesicles5
Transcriptome sequencing reveals neurotoxicity in embryonic neural stem/progenitor cells under heat stress5
Influence of experimental parameters on in vitro human skin permeation of Bisphenol A5
Evaluation of toxicity of heated tobacco products aerosol and cigarette smoke to BEAS-2B cells based on 3D biomimetic chip model5
Grandiflorenic acid isolated from Sphagneticola trilobata against Trypanosoma cruzi: Toxicity, mechanisms of action and immunomodulation5
Editorial Board5
Establishment of a human induced pluripotent stem cell derived alveolar organoid for toxicity assessment5
Effects of chlorpyrifos on non-cholinergic toxicity endpoints in immortalized and primary rat hepatocytes under normal and hepatosteatotic conditions5
Applications of Premature Chromosome Condensation technique for genetic analysis5
The use of in silico molecular modelling to screen potential estrogen mimics as part of medicines and agrochemicals development and product license applications.5
Nirmatrelvir has detrimental effects on sperm function by altering the PI3K/PDK1/AKT signaling pathway5
In vitro screening of per- and polyfluorinated substances (PFAS) for interference with seven thyroid hormone system targets across nine assays5
Silver nanoparticles induce formation of multi-protein aggregates that contain cadherin but do not colocalize with nanoparticles5
Multifunctional PLGA nanoparticles combining transferrin-targetability and pH-stimuli sensitivity enhanced doxorubicin intracellular delivery and in vitro antineoplastic activity in MDR tumor cells5
CircPDSS1 (hsa_circ_0017998) silencing induces ferroptosis in non-small-cell lung cancer cells by modulating the miR-137/SLC7A11/GPX4/GCLC axis5
Reference chemical database for the development and validation of in vitro alternatives to skin irritation and comparison of the performance of RhE models5
Corrigendum to “Exploring the combined impact of cisplatin and copper-cysteamine nanoparticles through Chemoradiation: An in-vitro study” [Toxicology in vitro 99 (2024) 105878].5
Oxidative Stress, Lysosomal Permeability, and Mitochondrial-Derived Vesicles Induced in NL-20 Human Bronchial Cells Exposed to Benzo[ghi]Perylene5
Scutellarin attenuates doxorubicin-induced oxidative stress, DNA damage, mitochondrial dysfunction, apoptosis and autophagy in H9c2 cells, cardiac fibroblasts and HUVECs5
Discovery of potent antitubercular agents: Design, synthesis and biological evaluation of 4-(3-(4-substitutedpiperazin-1-yl)-quinoxalin-2-yl)-naphthalen-1-ol analogues5
Modeling the antioxidant properties of the eye reduces the false-positive rate of a nonanimal eye irritation test (OptiSafe)5
Characterization of the intestinal transport mechanism of polystyrene microplastics (MPs) and the potential inhibitory effect of green tea extracts on MPs intestinal absorption5
Editorial Board5
Paclitaxel is evidence to reduce growing ovarian follicle growth in mice model study5
Effects of polystyrene micro- and nanoplastics on androgen- and estrogen receptor activity and steroidogenesis in vitro5
Synthesis of homogeneous spherical selenium nanoparticles through a chemical method for cancer therapy applications5
Pristimerin exhibits anti-cancer activity by inducing ER stress and AKT/GSK3β pathway through increasing intracellular ROS production in human esophageal cancer cells5
Assessing the safety of midazolam: A comprehensive analysis of adverse events from FAERS5
A multiparametric and orthogonal approach indicates low toxicity for zein nanoparticles in a repellent formulation5
PBTK modeled perfluoroalkyl acid kinetics in zebrafish eleutheroembryos suggests impacts on bioconcentrations by chorion porosity dynamics4
Prediction of skin sensitization using machine learning4
Toxicological evaluation of fluorescent 11-mercaptoundecanoic gold nanoclusters as promising label-free bioimaging probes in different cancer cell lines4
Tetrazolium–based colorimetric assays underestimat the direct antitumor effects of anti-VEGF agent bevacizumab4
Nickel nanoparticles affect the migration and invasion of HTR-8/SVneo cells by downregulating MMP2 through the PI3K/AKT pathway4
Predicting the skin sensitizing potential of pesticides using Pred-skin 3.0–A web-based prediction tool4
Akt and MAPK/ERK signaling regulate neurite extension in adult neural progenitor cells but do not directly mediate disruption of cytoskeletal structure and neurite dynamics by low-level silver nanopar4
Assessment of silver nanoparticles' antitumor effects: Insights into cell number, viability, and morphology of glioblastoma and prostate cancer cells4
Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening4
Modulation of adipogenesis and lipogenesis by indomethacin and pantoprazole4
The correlation of haptenation of gold nanoparticles and cysteine modified screen printed carbon electrode by impedance technique with local lymph node assay data4
In vitro neurotoxic potential of emerging flame retardants on neuroblastoma cells in an acute exposure scenario4
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