Toxicology in Vitro

Papers
(The median citation count of Toxicology in Vitro is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Dinaciclib inhibits the growth of acute myeloid leukemia cells through either cell cycle-related or ERK1/STAT3/MYC pathways66
Evaluation of in vitro cornea models for quantifying destructive effects of chemicals49
Evaluation of an imaging-based in vitro screening platform for estrogenic activity with OECD reference chemicals43
Editorial Board43
Prediction of acute oral toxicity using the Hansen solubility parameter34
Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array34
In vitro safety evaluation of sunscreen formulation from nanostructured lipid carriers using human cells and skin model34
Metformin and buparlisib synergistically induce apoptosis of non-small lung cancer (NSCLC) cells via Akt/FoxO3a/Puma axis31
Construction of an in vitro simulated one compartment extravascular administration model and its comparison with classic in vitro administration model in copper chloride induced HepG2 cell death31
Emerging trends in immunotoxin targeting cancer stem cells30
Mechanism for inhibition of cytotoxicity of Shiga toxin by luteolin29
Using cimetidine to mitigate cisplatin-induced ototoxicity29
The selected epigenetic effects of phthalates: DBP, BBP and their metabolites: MBP, MBzP on human peripheral blood mononuclear cells (In Vitro)28
Protective effects of silibinin against ethanol- or acetaldehyde-caused damage in liver cell lines involve the repression of mitochondrial fission27
Essential oil from Ocimum carnosum induces ROS mediated mitochondrial dysfunction and intrinsic apoptosis in HL-60 cells27
Minimum information for studies of extracellular vesicles (MISEV) as toolbox for rigorous, reproducible and homogeneous studies on extracellular vesicles26
Organochlorine pesticides disrupt T helper cell regulation and reduce IL-2 and IFN-γ favoring infection and production of autoantibodies among pemphigus patients26
In vitro genotoxic and antigenotoxic effects of an exopolysaccharide isolated from Lactobacillus salivarius KC27L24
Development of a human FaFg prediction system for polyphenols using human induced pluripotent stem cell-derived small intestinal epithelial cells24
Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol23
An in vitro nerve agent brain poisoning transwell model for convenient and accurate antidote evaluation23
Comparative analyses of transcriptome sequencing and carcinogenic exposure toxicity of nicotine and 6-methyl nicotine in human bronchial epithelial cells23
Cytotoxicity reduction by O-nicotinoylation of antiviral 6-benzylaminopurine ribonucleosides23
The evaluation of anticancer activity by synthesizing 5FU loaded albumin nanoparticles by exposure to UV light23
Benzo[b]fluoranthene (B[b]F) affects apoptosis, oxidative stress, mitochondrial membrane potential and expressions of blood-brain barrier markers in microvascular endothelial cells22
In-house performance assessment of 3D QobuR-Reconstructed Human Cornea-Like Epithelium (RhCE) for the evaluation of eye hazard22
Machine learning predictive classification models for the carcinogenic activity of activated metabolites derived from aromatic amines and nitroaromatics22
A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells21
Genotoxicity of putrescine and its effects on gene expression in HepG2 cell line21
Lupeol-loaded PLGA particles conserve anti-topoisomerase activity and decrease the cytotoxicity of lupeol20
Silencing Nrf2 in cisplatin resistant non-small cell lung cancer cells augments sensitivity towards EGFR inhibitor20
Can TK-TD modelling bridge the gap between in vitro and in vivo mammalian toxicity data?20
Nimbolide-encapsulated PLGA nanoparticles induces Mesenchymal-to-Epithelial Transition by dual inhibition of AKT and mTOR in pancreatic cancer stem cells20
Sens-ocular model: Cell-based assay to evaluate eye stinging potential of chemicals and baby cosmetic formulations.20
Editorial Board19
Influence of bile acids on the cytotoxicity of chemicals in cultivated human hepatocytes19
Physodic acid sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis18
TGF-β1/SMADs signaling involved in alleviating inflammation induced by nanoparticulate titanium dioxide in BV2 cells18
Phloretin exhibits potential food-drug interactions by inhibiting human UDP-glucuronosyltransferases in vitro18
Streptomycin generates oxidative stress in melanin-producing cells: In vitro study with EPR spectroscopy evidence17
Assessment of the utility of the novel Phenion® full thickness human skin model for detecting the skin irritation potential of antimicrobial cleaning products17
Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system17
Antibiotics reduce intestinal bile acid reuptake in an in vitro model system17
Anti-migratory and cytotoxic effect of indole derivative in C6 glioma cells16
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells16
Analysis of reproducibility and robustness of OrganoPlate® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs16
The effect of endocrine disrupting chemicals on the vitronectin-receptor (integrin αvβ3)-mediated cell adhesion of human umbilical vein endothelial cells16
Editorial Board15
Influence of alkylthio and arylthio derivatives of tert-butylquinone on the induction of DNA damage in a human hepatocellular carcinoma cell line (HepG2)15
Effects of radical scavengers for reactive oxygen species on vitamin K-induced phototoxicity under UVA irradiation15
Stronger prooxidative effects of chromium(VI) comparing to chromium(III) in endocrine and non-endocrine tissues with the thyroid being completely resistant to antioxidant protection15
Sinapic acid alleviates glutamate-induced excitotoxicity by inhibiting neuroinflammation and endoplasmic reticulum stress pathway in C6 glioma cells15
Isolation and characterization of bovine Limbal mesenchymal stromal cells for application in ocular toxicity studies15
Development of natural cosmetic emulsion using the by-product of Lecythis pisonis seed15
Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells15
Species differences in microsomal metabolism of hydroxychloroquine15
In vitro inhibitory effects of selumetinib on activity of human UDP-glucuronosyltransferases and prediction of in vivo drug-drug interactions14
Studying the intracellular bile acid concentration and toxicity in drug-induced cholestasis: Comprehensive LC-MS/MS analysis with human liver slices14
Characterization of elements, PAHs, AhR-activity and pro-inflammatory responses of road tunnel-derived particulate matter in human hepatocyte-like and bronchial epithelial cells14
Overdose with the anesthetic propofol causes hematological cytotoxicity and immune cell alteration in an experimental ex vivo whole blood culture model14
Curcumin induces mitophagy by promoting mitochondrial succinate dehydrogenase activity and sensitizes human papillary thyroid carcinoma BCPAP cells to radioiodine treatment14
The importance of metrological tools to implementation of alternative method OECD TG 42814
In vitro immune and redox response induced by cationic cellulose-based nanomaterials14
Nonylphenol reduced the number of haploids in in vitro spermatogenesis of the endangered cyprinid Gnathopogon caerulescens13
Developmental toxicity testing of unsubstituted and methylated 4- and 5-ring polycyclic aromatic hydrocarbons using the zebrafish embryotoxicity test13
Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates13
Optimization of in vitro culture of honeybee nervous tissue for pesticide risk assessment13
Organic ultraviolet filters regulate hyaluronan metabolism in human epidermal keratinocytes through the phosphatidylinositol 3-kinase pathway13
Characterization of prodigiosin pigment by Serratia marcescens and the evaluation of its bioactivities13
Selective inhibition of HDAC6 by N-acylhydrazone derivative reduces the proliferation and induces senescence in carcinoma hepatocellular cells13
Fragrances as a trigger of immune responses in different environments13
ESTIV 2022: Key enabling non-animal technologies for research, education and testing13
Photodynamic therapy with curcumin and near-infrared radiation as an antitumor strategy to glioblastoma cells13
Editorial Board13
The effects of Acyclovir administration to NCI-H1975 non-small cell lung cancer cells12
Frankenstein's followers. Maintenance of human cells outside the body. Issue 112
Involvement of Sirt1-FoxO3a-Bnip3 axis and autophagy mediated mitochondrial turnover in according protection to hyperglycemic NRK-52E cells by Berberine12
Differential comparison of genotoxic effects of aristolochic acid I and II in human cells by the mass spectroscopic quantification of γ-H2AX12
First toxicity profile of aminoindane-based new psychoactive substances: 2-aminoindane (2-AI, CAS: 2975-41-9) and N-Methyl-2-aminoindane (NM-2-AI, CAS: 24445–44–1) – comprehensive prediction of toxico12
The effect of airborne Palladium nanoparticles on human lung cells, endothelium and blood – A combinatory approach using three in vitro models12
Editorial Board12
Benzo[a]pyrene inhibits myoblast differentiation through downregulating the Hsp70-MK2-p38MAPK complex12
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level12
Corrigendum to “Zearalenone causes embryotoxicity and induces oxidative stress and apoptosis in differentiated human embryonic stem cells” [Toxicology in Vitro 54 (2019) 243–250]12
In vitro assessment of cytotoxicity of spent fluid catalytic cracking refinery catalysts on cell lines and identification of critical toxic metals12
Cigarette smoke extract decreases human bone marrow mesenchymal stromal cell adipogenic differentiation12
Silibinin inhibits ethanol- or acetaldehyde-induced ferroptosis in liver cell lines12
Evaluating the QileX-RhE skin corrosion test for chemical subcategorization in accordance with OECD TG 43112
Effects of antimicrobial metal nanoparticles on characteristics and function properties of mouse mesenchymal stem cells12
Synergistic and divergent effects of dietary sugars on hepatocyte viability and steatosis12
TNF-α and MMPs mediated mucus hypersecretion induced by cigarette smoke: An in vitro study12
Comprehensive studies on the biological activities of human metastatic (MDA-MB-231) and non-metastatic (MCF-7) breast cancer cell lines, directly or combinedly treated using non-thermal plasma-based a12
Influence of cellular redox environment on aryl hydrocarbon receptor ligands induced melanogenesis11
Intragenic antimicrobial peptide Hs02 toxicity against leukemia cell lines is associated with increased expression of select pyroptotic components11
Mesoporous nanosilica: A thromboprotective nanomaterial for biomedical applications11
In vitro human skin absorption of ethyl salicylate, pentyl salicylate, and (Z)-3-hexenyl salicylate from topical formulations: Effects on permeation and distribution11
4-O-methylascochlorin-stimulated HIF-1α expression induces the epithelial mesenchymal transition and cell survival in breast cancer cells11
4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl111
Effects of an environmental chemical mixture on early-stage embryo development: In vitro evidence from human embryonic stem cells11
How to use an in vitro approach to characterize the toxicity of airborne compounds11
In vitro toxicity of two functionalized reduced graphene oxide materials with potential application in food packaging11
Editorial Board11
Effects of culture media on gene expression in reconstructed human epidermis and THP-1 monocytes for skin sensitization evaluation in co-culture systems11
Transcription Factor yin-Yang 1 augments nucleoporin 93 oncogene activity and modulates bladder Cancer malignancy11
Use of centromeric probe to identify micronuclei origin and its advantages in genetic toxicology studies11
Everolimus prevents doxorubicin-induced apoptosis in H9c2 cardiomyocytes but not in MCF-7 cancer cells: Cardioprotective roles of autophagy, mitophagy, and AKT10
Acute cytotoxicity, genotoxicity, and apoptosis induced by petroleum VOC emissions in A549 cell line10
Risk assessment of chlorophenols (CPs) exposure in vitro:Inhibition of sulfotransferases (SULTs) activity10
Acrylamide-induced damage to postsynaptic plasticity is CYP2E1 dependent in an SH-SY5Y co-culture system10
Potential risk of drug-drug interactions of ponatinib via inhibition against human UDP-glucuronosyltransferases10
Exosome proteomics study of the effects of traditional cigarettes and electronic cigarettes on human bronchial epithelial cells10
Risperidone-induced bioenergetic disruption in the isolated human peripheral blood monocytes10
Differential cytotoxic activity of pharmacological inhibitors of IGF1R-related pathways in JAK2V617F driven cells10
N-acetyl-L-cysteine attenuated the toxicity of ZIF-8 on EA.hy926 endothelial cells by wnt/β-catenin pathway10
Bufadienolides from the Bufo viridis toad venom exert cytotoxic effects on cancer cells by inducing cell apoptosis and cell cycle arrest10
Strategies for the evaluation of the eye irritation potential of different types of surfactants and silicones used in cosmetic products10
Identification of the function and regulatory network of circ_009773 in DNA damage induced by nanoparticles of neodymium oxide10
Pracaxi oil affects xenobiotic metabolisms, cellular proliferation, and oxidative stress without cytotogenotoxic effects in HepG2/C3A cells10
Transdermal permeation of inorganic cerium salts in intact human skin10
The SNHG10-miR-495-3p-PTEN axis is involved in sevoflurane-mediated protective effects in cardiomyocytes against hypoxia/reoxygenation injury10
Effects of methylation of arginine residue 83 on the enzymatic activity of human arsenic (+3 oxidation state) methyltransferase9
The role of efflux transporters in cytotoxicity and intracellular concentration of chlorpyrifos and chlorpyrifos oxon in human cell lines9
Study on percutaneous penetration of representative cosmetic ingredients in a baby wipe product in an in vitro diaper rash skin model9
Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells9
Testing chemicals for CYP19 inhibition: Comparison of a modified H295R steroidogenesis assay to a commercial fluorometric enzyme inhibition kit9
Effects of di-(2-ethylhexyl) phthalate and its metabolites on transcriptional activity via human nuclear receptors and gene expression in HepaRG cells9
Delta-9 tetrahydrocannabinol (THC) effects on the cortisol stress response in bovine granulosa cells9
Transcriptomic changes and mitochondrial toxicity in response to acute and repeat dose treatment with brequinar in human liver and kidney in vitro models9
(-)-Epigallocatechin gallate as an inhibitor of hemoglobin-catalyzed lipid oxidation: molecular mechanism of action and nutritional application9
Perfluorooctanoic acid inhibits cell proliferation through mitochondrial damage9
Investigating the mechanisms of action of thyroid disruptors: A multimodal approach that integrates in vitro and metabolomic analysis9
Washing with buffered vitamin C after corrosive chemical (sodium hypochlorite) exposure reduces ocular depth of injury9
Editorial Board9
High-throughput assay for predicting diarrhea risk using a 2D human intestinal stem cell-derived model9
Cytotoxicity of ZnO nanoparticles in human melanocyte cells in the presence or absence of UV radiation: A preliminary comparative study with TiO2 nanoparticles9
6:2 fluorotelomer sulfonate as a safer alternative to PFOS: Comparative cytotoxicity and oxidative stress mechanisms in pancreatic β-cells (INS-1 model)9
Normalization of organ-on-a-Chip samples for mass spectrometry based proteomics and metabolomics via Dansylation-based assay9
Polystyrene nanoparticles incorporate into the endoplasmic reticulum and disturb translation during meiotic maturation in mouse oocytes9
Risk assessment of the inhibition of hydroxygenkwanin on human and rat cytochrome P450 by cocktail method9
Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR signaling pathway9
Effect of serotonin 7 receptors and transcript variants on RIN-5F pancreatic beta cell line9
Mictlan-D3: A novel medium sized RGD-Disintegrin obtained from Crotalus mictlantecuhtli venom, in vitro tested against human breast Cancer and endothelial cells9
Evaluation of toxicological aspects of three new benzoxazole compounds with sunscreen photophysical properties using in silico and in vitro methods9
Busulfan-induced hepatic sinusoidal endothelial cell injury: Modulatory role of pirfenidone for therapeutic purposes9
m-Cresol,a pesticide intermediate, induces hepatotoxicity and behavioral abnormalities in zebrafish larvae through oxidative stress, apoptosis9
In vitro eye irritation testing models may play pivotal role in effort to pursue mild baby cleansers9
A battery of in silico models application for pesticides exerting reproductive health effects: Assessment of performance and prioritization of mechanistic studies8
The impact of bisphenol AF on skeletal muscle function and differentiation in vitro8
Telomere loss is accompanied by decreased pool of shelterin proteins TRF2 and RAP1, elevated levels of TERRA and enhanced glycolysis in imatinib-resistant CML cells8
Toxicity of New Psychoactive Substance (NPS): Threo-4-methylmethylphenidate (4-Mmph) – Prediction of toxicity using in silico methods8
Long-term in vitro exposure of human granulosa cells to the mixture of endocrine disrupting chemicals found in human follicular fluid disrupts steroidogenesis8
Chronic exposure to palmitic acid-induced adipocyte hypertrophy and altered batokine gene expression in T37i brown adipocytes8
Blocking Autophagy by the Two-Pore Channels Antagonist Tetrandrine Improves Sorafenib-Induced Death of Hepatocellular Carcinoma Cells8
Differential DNA damage response and cell fate in human lung cells after exposure to genotoxic compounds8
Interactions of oleanane pentacyclic triterpenoids with human organic anion transporting polypeptide 1B1 and 1B38
Editorial Board8
Mitochondria oxidative stress mediated nicotine-promoted activation of pancreatic stellate cells by regulating mitochondrial dynamics8
Dendritic cells activated by cimetidine induce Th1/Th17 polarization in vitro and in vivo8
Mettl3-mediated transcriptome-wide m6A methylation induced by cigarette smoking in human bronchial epithelial cells8
The Alarming Consequences of Workforce Reductions at the FDA, EPA, NIH and CDC in the United States8
Hydroxylation markedly alters how the polychlorinated biphenyl (PCB) congener, PCB52, affects gene expression in human preadipocytes8
A novel O2- (2,4-dinitrophenyl) diazeniumdiolate inhibits hepatocellular carcinoma migration, invasion, and EMT through the Wnt/β-catenin pathway8
Chemometric modeling of acute toxicity of diverse aromatic compounds against Rana japonica8
STF-083010 an inhibitor of IRE1α endonuclease activity affects mitochondrial respiration and generation of mitochondrial membrane potential8
Application of ToxCast/Tox21 data for toxicity mechanism-based evaluation and prioritization of environmental chemicals: Perspective and limitations7
Lead inhibits the odontogenic differentiation potential of dental pulp stem cells by affecting WNT1/β-catenin signaling and related miRNAs expression7
Tributyltin propionate and tributyltin salicylate represent novel RXR ligands: Effects on transcriptional activity of thyroid hormone receptor and vitamin D3 receptor7
Triphenyltin chloride exposure inhibits meiotic maturation of mouse oocytes by disrupting cytoskeleton assembly and cell cycle progression7
Impact of gadolinium oxide based nanoparticles on genotoxic, cytotoxic and oxidative stress in human lymphocytes7
Cytotoxicity assay to assess eye irritation – A comparison with other methods and possible strategies for use7
Cannabinoids and standardized cannabis extracts inhibit migration, invasion, and induce apoptosis in MCF-7 cells through FAK/MAPK/Akt/NF-κB signaling7
Binding of plutonium and americium to small molecular weight ligands favors their paracellular transfer across lung epithelium in vitro7
Establishment of a human induced pluripotent stem cell derived alveolar organoid for toxicity assessment7
METTL3 regulates FAM83D m6A modification to accelerate tumorigenesis of triple-negative breast cancer via the Wnt/β-catenin pathway7
Effect of curcumin on the embryotoxic effect of ethanol in a zebrafish model7
The mechanism of thrombocytopenia caused by cholesterol-conjugated antisense oligonucleotides7
miRNA-6515-5p regulates particulate matter-induced inflammatory responses by targeting CSF3 in human bronchial epithelial cells7
Curcumin-loaded emulsome nanoparticles induces apoptosis through p53 signaling pathway in pancreatic cancer cell line PANC-17
Effects of chlorpyrifos on non-cholinergic toxicity endpoints in immortalized and primary rat hepatocytes under normal and hepatosteatotic conditions7
Discovery of potent antitubercular agents: Design, synthesis and biological evaluation of 4-(3-(4-substitutedpiperazin-1-yl)-quinoxalin-2-yl)-naphthalen-1-ol analogues7
Effects of an environmentally relevant mixture of organochlorine pesticide compounds on adipogenesis and adipocyte function in an immortalized human adipocyte model7
Proton pump inhibitors interfere with the anti-tumor potency of RC48ADC7
Counterions determine uptake and effects of aluminum in human intestinal and liver cells7
Inter-laboratory validation study of an in vitro glucocorticoid receptor transactivation assay for testing potential endocrine disrupting chemicals7
Chemotherapeutic effect of baicalein/epirubicin combination against liver cell carcinoma in-vitro: Inducing apoptosis and autophagy7
Antifungal climbazole alters androgenic pathways in mammalian cells7
Arsenic trioxide inhibits the response of primary human B cells to influenza virus A in vitro7
Liposomal nanoparticles containing adenosine triphosphate targeted by heart-specific peptide ligands as antidotes for aluminum phosphide poisoning in isolated rat cardiomyocyte cell line7
Evaluation of the inhibitory effects of antigout drugs on human carboxylesterases in vitro7
N-acetylcysteine protect inner hair cells from cisplatin by alleviated celluar oxidative stress and apoptosis7
Scutellarin attenuates doxorubicin-induced oxidative stress, DNA damage, mitochondrial dysfunction, apoptosis and autophagy in H9c2 cells, cardiac fibroblasts and HUVECs7
Suitability of human HepaRG cells and liver spheroids as in vitro model to investigate the bioactivation of the organothiophosphate pesticide parathion7
Suppression of lncRNA Snhg1 inhibits high glucose-induced inflammation and proliferation in mouse mesangial cells7
CircPDSS1 (hsa_circ_0017998) silencing induces ferroptosis in non-small-cell lung cancer cells by modulating the miR-137/SLC7A11/GPX4/GCLC axis7
Oxidative Stress, Lysosomal Permeability, and Mitochondrial-Derived Vesicles Induced in NL-20 Human Bronchial Cells Exposed to Benzo[ghi]Perylene6
The neuroprotective role of chlorogenic acid and Fisetin in differentiated neuronal cell line-SHSY5Y against amyloid-β-induced neurotoxicity6
Evaluation of toxicity of heated tobacco products aerosol and cigarette smoke to BEAS-2B cells based on 3D biomimetic chip model6
Cytotoxic and immunotoxic profile of HgCl2 involves alterations in purinergic signaling through the P2X7/NLRP3/CASP-1/IL-1β pathway: An in vitro study using human blood immune cells6
Effects of iron oxide nanoparticles on the gene expression profiles of cerebral endotheliocytes and astrocytes6
Different cellular mechanism of imidacloprid and acetamiprid by a combined targeted lipidomics and metabolomics approach in Neuro-2a cells6
Dosing metric in cellular experiments: The mol/cell metric has its limitations6
Heat shock protein HSPA8 impedes hemin-induced cellular-toxicity in liver6
Editorial Board6
A multiparametric and orthogonal approach indicates low toxicity for zein nanoparticles in a repellent formulation6
Reference chemical database for the development and validation of in vitro alternatives to skin irritation and comparison of the performance of RhE models6
The use of in silico molecular modelling to screen potential estrogen mimics as part of medicines and agrochemicals development and product license applications.6
Nicotinamide mononucleotide inhibits oxidative stress-induced damage in a SIRT1/NQO-1-dependent manner6
Assessing the safety of midazolam: A comprehensive analysis of adverse events from FAERS6
Nirmatrelvir has detrimental effects on sperm function by altering the PI3K/PDK1/AKT signaling pathway6
Corrigendum to “Exploring the combined impact of cisplatin and copper-cysteamine nanoparticles through Chemoradiation: An in-vitro study” [Toxicology in vitro 99 (2024) 105878].6
Effect of long-term inorganic arsenic exposure on erythropoietin production in vitro6
Silver nanoparticles induce formation of multi-protein aggregates that contain cadherin but do not colocalize with nanoparticles6
Vincristine promotes differential levels of apoptosis, mitotic catastrophe, and senescence depending on the genetic background of glioblastoma cells6
Validation of the SkinEthic HCE Time-to-Toxicity test method for eye hazard classification of chemicals according to UN GHS6
Paclitaxel is evidence to reduce growing ovarian follicle growth in mice model study6
Editorial Board6
Editorial Board6
Synthesis of homogeneous spherical selenium nanoparticles through a chemical method for cancer therapy applications6
Grandiflorenic acid isolated from Sphagneticola trilobata against Trypanosoma cruzi: Toxicity, mechanisms of action and immunomodulation6
Effects of polystyrene micro- and nanoplastics on androgen- and estrogen receptor activity and steroidogenesis in vitro6
Selected phytocannabinoids inhibit SN-38- and cytokine-evoked increases in epithelial permeability and improve intestinal barrier function in vitro6
Characterization of the intestinal transport mechanism of polystyrene microplastics (MPs) and the potential inhibitory effect of green tea extracts on MPs intestinal absorption6
Engineering of gelatin scaffold by extracellular matrix of Sertoli cells for embryonic stem cell proliferation6
Applications of Premature Chromosome Condensation technique for genetic analysis6
Circ_0005758 impedes gastric cancer progression through miR-1229-3p/GCNT4 feedback loop6
Clarify the potential cholestatic hepatotoxicity components from Chinese Herb Medicine and metabolism’s role via hBSEP vesicles and S9/hBSEP vesicles6
High-content analysis of testicular toxicity of BPA and its selected analogs in mouse spermatogonial, Sertoli cells, and Leydig cells revealed BPAF induced unique multinucleation phenotype associated 6
Pristimerin exhibits anti-cancer activity by inducing ER stress and AKT/GSK3β pathway through increasing intracellular ROS production in human esophageal cancer cells6
Editorial Board6
Transcriptome sequencing reveals neurotoxicity in embryonic neural stem/progenitor cells under heat stress6
In vitro screening of per- and polyfluorinated substances (PFAS) for interference with seven thyroid hormone system targets across nine assays6
Inhibitory effects of the main metabolites of Apatinib on CYP450 isozymes in human and rat liver microsomes5
Evaluating variations in bilirubin glucuronidation activity by protease inhibitors in canine and human primary hepatocytes cultured in a 3D culture system5
Corrigendum to “Novel Diphenyl urea derivative serves as an inhibitor on human lung cancer cell migration by disrupting EMT via Wnt/β-catenin and PI3K/Akt signaling” [Toxicology in Vitro 69 (2020) 1055
Reverse relation between cytotoxicity and Polyethylenimine/DNA ratio, the effect of using HEPES-buffered saline (HBS) medium in gene delivery5
Circular RNA PVT1 inhibits tendon stem/progenitor cell senescence by sponging microRNA-199a-5p5
Lovastatin impairs cellular proliferation and enhances hyaluronic acid production in fibroblast-like synoviocytes5
Skin barrier function for regulatory skin absorption tests and effects on testosterone and sucrose absorption5
Marked differences in thyroxine (T4) metabolism following in vitro exposure of Wistar rat and human hepatocytes to several reference CAR/PXR nuclear receptor activators5
Pro-inflammatory and genotoxic responses by metal oxide nanomaterials in alveolar epithelial cells and macrophages in submerged condition and air-liquid interface: An in vitro-in vivo correlation stud5
Editorial Board5
New gold (III) cyanide complex TGS 121 induces ER stress, proteasome inhibition and death of Ras-hyperactivated cells5
Toxicoproteomic study of fipronil in SH-SY5Y cells reveals induction of endoplasmic reticulum stress and necrotic cell death as neurodegenerative mechanisms5
Three dimensional reconstruction of skin with melanoma: A model for study of invasion in vitro5
In vitro assessment of the genotoxic and cytotoxic effects of clarified açai (Euterpe oleracea MART) extract in a gastric cancer cell line (AGP01 cells).5
In vitro impacts of polystyrene microplastics and environmental pollutants on ethoxyresorufin-O-deethylase and glutathione S-transferase activity in Mossambica tilapia5
Interaction of mycotoxins zearalenone, α-zearalenol, and β-zearalenol with cytochrome P450 (CYP1A2, 2C9, 2C19, 2D6, and 3A4) enzymes and organic anion transporting polypeptides (OATP1A2, OATP1B1, OATP5
Cattle farm dust alters cytokine levels in human airway construct model5
Assessment of the skin sensitization potential of fragrance ingredients using the U-SENS™ assay5
Nilotinib exhibits less toxicity than imatinib and influences the immune state by modulating iNOS, p-p38 and p-JNK in LPS/IFN gamma-activated macrophages5
0.10200691223145