Toxicology in Vitro

Article	Citations
Emerging trends in immunotoxin targeting cancer stem cells	73
Bufadienolides from the Bufo viridis toad venom exert cytotoxic effects on cancer cells by inducing cell apoptosis and cell cycle arrest	58
Predicting the potential risks posed by antidepressants as emerging contaminants in fish based on network pharmacological analysis	53
Editorial Board	41
Vincristine promotes differential levels of apoptosis, mitotic catastrophe, and senescence depending on the genetic background of glioblastoma cells	35
Clarify the potential cholestatic hepatotoxicity components from Chinese Herb Medicine and metabolism’s role via hBSEP vesicles and S9/hBSEP vesicles	32
Evaluation of an imaging-based in vitro screening platform for estrogenic activity with OECD reference chemicals	28
Increased effects of 2,5-dimethylcelecoxib on sensitivity of hepatocellular carcinoma cells to sorafenib via CYP3A5 expression and activation of AMPK	27
Exosome proteomics study of the effects of traditional cigarettes and electronic cigarettes on human bronchial epithelial cells	27
Transdermal permeation of inorganic cerium salts in intact human skin	26
Paclitaxel is evidence to reduce growing ovarian follicle growth in mice model study	24
Editorial Board	23
In vitro safety evaluation of sunscreen formulation from nanostructured lipid carriers using human cells and skin model	22
Editorial Board	22
Apparent limitations of OECD TG 431 for classification of acrylic- and methacrylic-based adhesives	21
Gellan gum hydrogels cross-linked with carbodiimide stimulates vacuolation of human tooth-derived stem cells in vitro	21
PBA alleviates cadmium-induced mouse spermatogonia apoptosis by suppressing endoplasmic reticulum stress	21
N-acetyl-L-cysteine attenuated the toxicity of ZIF-8 on EA.hy926 endothelial cells by wnt/β-catenin pathway	21
Vanillin attenuates CdCl2-induced cytotoxicity in isolated human erythrocytes	20
Validation of the SkinEthic HCE Time-to-Toxicity test method for eye hazard classification of chemicals according to UN GHS	20
Environmental dose of 16 priority-controlled PAHs mixture induce damages of vascular endothelial cells involved in oxidative stress and inflammation	20
Interlaboratory prevalidation of a new in vitro transcriptional activation assay for the screening of (anti-)androgenic activity of chemicals using the UALH-hAR cell line	19
Toxicological damages on copper exposure to IgM+ B cells of Nile tilapia (Oreochromis niloticus) and mitigation of its adverse effects by β-glucan administration	19
The SNHG10-miR-495-3p-PTEN axis is involved in sevoflurane-mediated protective effects in cardiomyocytes against hypoxia/reoxygenation injury	19
Editorial Board	19

Hepatic stellate cell activation by TGFβ induces hedgehog signaling and endoplasmic reticulum stress simultaneously	18
Hyaluronic acid promotes calcium oxalate crystal growth, crystal-cell adhesion, and crystal invasion through extracellular matrix	18
Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells	18
The dissolution of stone wool fibers with sugar-based binder and oil in different synthetic lung fluids	17
The selected epigenetic effects of phthalates: DBP, BBP and their metabolites: MBP, MBzP on human peripheral blood mononuclear cells (In Vitro)	17
Toxic effects of gunshot fumes from different ammunitions for small arms on lung cells exposed at the air liquid interface	17
PSAT1 promotes autophagy to resist insufficient autophagy caused by cigarette smoke extract in human airway epithelial cells	16
Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals	16
Using cell culture systems from the Persian Gulf Arabian yellowfin sea bream, Acanthopagrus arabicus, to assess the effects of dexamethasone on gonad and brain aromatase activity and steroid productio	16
Amantadine mitigates the cytotoxic and genotoxic effects of doxorubicin in SH-SY5Y cells and reduces its mutagenicity	15
LINC02535 + miR-30a-5p combination enhances proliferation and inhibits apoptosis in metastatic breast Cancer cells	15
Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway	15
Ursodeoxycholic acid and 18β-glycyrrhetinic acid alleviate ethinylestradiol-induced cholestasis via downregulating RORγt and CXCR3 signaling pathway in iNKT cells	15
Potential risk of drug-drug interactions of ponatinib via inhibition against human UDP-glucuronosyltransferases	15
Bisphenol a accelerates the glucolipotoxicity-induced dysfunction of rat insulinoma cell lines: An implication for a potential risk of environmental bisphenol a exposure for individuals susceptible to	15
Heat shock protein HSPA8 impedes hemin-induced cellular-toxicity in liver	14
Construction of an in vitro simulated one compartment extravascular administration model and its comparison with classic in vitro administration model in copper chloride induced HepG2 cell death	14
Acrylamide-induced damage to postsynaptic plasticity is CYP2E1 dependent in an SH-SY5Y co-culture system	14
Ex vivo skin diffusion and decontamination studies of titanium dioxide nanoparticles	14
Protective effects of silibinin against ethanol- or acetaldehyde-caused damage in liver cell lines involve the repression of mitochondrial fission	14
Risperidone-induced bioenergetic disruption in the isolated human peripheral blood monocytes	14
The recovery from taxane mediated apoptosis in PC-3 castration-resistant metastatic prostate cancer cells	14
Scopoletin protects INS-1 pancreatic β cells from glucotoxicity by reducing oxidative stress and apoptosis	14
Acute cytotoxicity, genotoxicity, and apoptosis induced by petroleum VOC emissions in A549 cell line	14
Integrated high-throughput drug screening microfluidic system for comprehensive ocular toxicity assessment	13
Dinaciclib inhibits the growth of acute myeloid leukemia cells through either cell cycle-related or ERK1/STAT3/MYC pathways	13
Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol	13
Evaluation of in vitro cornea models for quantifying destructive effects of chemicals	13
Precision cut tissue slices to investigate the effects of triclosan exposure in Mytilus galloprovincialis	13
Dissolution of titanium dioxide nanoparticles in synthetic biological and environmental media to predict their biodurability and persistence	13
High-content analysis of testicular toxicity of BPA and its selected analogs in mouse spermatogonial, Sertoli cells, and Leydig cells revealed BPAF induced unique multinucleation phenotype associated	13
Endoplasmic reticulum stress regulates autophagic response that is involved in Saikosaponin a-induced liver cell damage	13
Protective role of fetal bovine serum on PLHC-1 spheroids exposed to a mixture of plastic additives: A lipidomic perspective	13
Mechanism of VKORC1 and VKORC1L1 signaling in the effects of sodium dehydroacetate on coagulation factors in rat hepatocytes	13
PFOS disrupts key developmental pathways during hiPSC-derived cardiomyocyte differentiation in vitro	13
Everolimus prevents doxorubicin-induced apoptosis in H9c2 cardiomyocytes but not in MCF-7 cancer cells: Cardioprotective roles of autophagy, mitophagy, and AKT	13
Monolayer (2D) or spheroids (3D) cell cultures for nanotoxicological studies? Comparison of cytotoxicity and cell internalization of nanoparticles	13
MicroRNA-184 attenuates hypoxia and oxidative stress-related injury via suppressing apoptosis, DNA damage and angiogenesis in an in vitro age-related macular degeneration model	12
In vitro evidence of the influence of complexation of Pu and Am on uptake by human lung epithelial cells Calu-3	12
MiR-30a inhibits silica dust-induced epithelial-mesenchymal transition by targeting Snail	12
Arsenic-induced autophagy regulates apoptosis in AML-12 cells	12
Gaining insight into genotoxicity with the comet assay in inhomogenoeous exposure scenarios: The effects of tritiated steel and cement particles on human lung cells in an inhalation perspective	12
Differential cytotoxic activity of pharmacological inhibitors of IGF1R-related pathways in JAK2V617F driven cells	12
Limonene-carvacrol: A combination of monoterpenes with enhanced antileishmanial activity	12
PDE-5 inhibitors in selected herbal supplements from the Ghanaian market for better erectile function as tested by a bioassay	12
Metformin and buparlisib synergistically induce apoptosis of non-small lung cancer (NSCLC) cells via Akt/FoxO3a/Puma axis	12
Anticancer effect of paroxetine and amitriptyline on HT29 and A549 cell lines	12
Melatonin prevents blood-retinal barrier breakdown and mitochondrial dysfunction in high glucose and hypoxia-induced in vitro diabetic macular edema model	12
Organochlorine pesticides disrupt T helper cell regulation and reduce IL-2 and IFN-γ favoring infection and production of autoantibodies among pemphigus patients	12
Dosing metric in cellular experiments: The mol/cell metric has its limitations	11

Ascorbic acid specifically reduces the misclassification of nonirritating reactive chemicals in the OptiSafe™ macromolecular eye irritation test	11
Prediction of acute oral toxicity using the Hansen solubility parameter	11
Novel podophyllotoxin and benzothiazole derivative induces transitional morphological and functional changes in HaCaT cells	11
In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase	11
Assessment of the in vitro developmental toxicity of diethylstilbestrol and estradiol in the zebrafish embryotoxicity test	11
Biological effects of combustion-derived particles from different biomass sources on human bronchial epithelial cells	11
Pracaxi oil affects xenobiotic metabolisms, cellular proliferation, and oxidative stress without cytotogenotoxic effects in HepG2/C3A cells	11
Comparison of in vitro thyroxine (T4) metabolism between Wistar rat and human hepatocyte cultures	11
E-cigarettes induce toxicity comparable to tobacco cigarettes in airway epithelium from patients with COPD	11
Underlying mechanisms of cytotoxicity in HepG2 hepatocarcinoma cells exposed to arsenic, cadmium and mercury individually and in combination	11
Mogroside V exerts anti-inflammatory effects on fine particulate matter-induced inflammation in porcine alveolar macrophages	11
In silico modelling of acute toxicity of 1, 2, 4-triazole antifungal agents towards zebrafish (Danio rerio) embryos: Application of the Small Dataset Modeller tool	11
Circ_0005758 impedes gastric cancer progression through miR-1229-3p/GCNT4 feedback loop	11
Comparisons of segment-specific toxicity of platinum-based agents and cadmium using S1, S2, and S3 cells derived from mouse kidney proximal tubules	11
Strategies for the evaluation of the eye irritation potential of different types of surfactants and silicones used in cosmetic products	11
In silico prediction of chemical acute contact toxicity on honey bees via machine learning methods	11
Immortalized keratinocytes cells generates an effective model of Epidermal Human Equivalent for irritation and corrosion tests	10
Estrogen receptor/androgen receptor transcriptional activation of benzophenone derivatives and integrated approaches to testing and assessment (IATA) for estrogenic effects	10
Dihydrotanshinone I induces necroptosis and cell cycle arrest in gastric cancer through the PTPN11/p38 pathway	10
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets	10
Editorial Board	10
Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action	10
Nicotinamide mononucleotide inhibits oxidative stress-induced damage in a SIRT1/NQO-1-dependent manner	10
Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells	10
Knockdown of JMJD3 ameliorates cigarette smoke extract-triggered bronchial epithelial cell injury via ACSL4-dependent ferroptosis	10
Cross-species comparisons of plasma binding and considerations for data evaluation	10
New insights into the cytotoxic effects of Thymus vulgaris essential oil on the human triple-negative breast cancer cell line MDA-MB-231	10
Mechanism for inhibition of cytotoxicity of Shiga toxin by luteolin	10
Cell-based high-throughput screening for the evaluation of reactive metabolite formation potential	10
Corrigendum to “Cytotoxic and cytocompatible comparison among seven photoinitiators-triggered polymers in different tissue cells” [Toxicology in Vitro 72 (2021) 105103]	10
Puerarin attenuates LPS-induced inflammatory injury in gastric epithelial cells by repressing NLRP3 inflammasome-mediated apoptosis	10
Interferences in the yeast estrogen screen (YES) assay for evaluation of estrogenicity in environmental samples, chemical mixtures, and individual substances	10
Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array	10
Low concentrations of glyphosate alone affect the pubertal male rat meiotic step: An in vitro study	10
Identification of the function and regulatory network of circ_009773 in DNA damage induced by nanoparticles of neodymium oxide	10
Pre-validation of SENS-IS assay for in vitro skin sensitization of medical devices	9
In vitro eye irritation testing models may play pivotal role in effort to pursue mild baby cleansers	9
Development of a lung-liver in vitro coculture model for inhalation-like toxicity assessment	9
Diethylene glycol and its metabolites induce cell death in SH-SY5Y neuronal cells in vitro	9
Nickel nanoparticles affect the migration and invasion of HTR-8/SVneo cells by downregulating MMP2 through the PI3K/AKT pathway	9
An international validation study of the interleukin-2 luciferase leukocyte toxicity test (IL-2 Luc LTT) to evaluate potential immunosuppressive chemicals and its performance after use with the interl	9
PBTK modeled perfluoroalkyl acid kinetics in zebrafish eleutheroembryos suggests impacts on bioconcentrations by chorion porosity dynamics	9
A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells	9
In chemico sequential testing strategy for assessing the photoallegic potential	9
Amending the U-SENS™ skin sensitization test method for interfering auto-fluorescent chemicals	9
Calcium, magnesium and aluminium ions as decontaminating agents against dermal fluoride absorption following hydrofluoric acid exposure	9
An in vitro nerve agent brain poisoning transwell model for convenient and accurate antidote evaluation	9
Editorial Board	9
Curcumin ameliorates oxidized low-density lipoprotein (ox-LDL)-caused damage in human umbilical vein endothelial cells (HUVECs) through the miR-599/MYD88/NF-κB axis	9
Effects of tumor necrosis factor on undifferentiated and syncytialized placental choriocarcinoma BeWo cells	9
Microcystin-leucine arginine exhibits adverse effects on human aortic vascular smooth muscle cells in vitro	9
Comparative analyses of transcriptome sequencing and carcinogenic exposure toxicity of nicotine and 6-methyl nicotine in human bronchial epithelial cells	8
Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol	8
Cytotoxicity reduction by O-nicotinoylation of antiviral 6-benzylaminopurine ribonucleosides	8
Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species	8
Editorial Board	8
ISO 10993-23 In vitro irritation testing for medical devices: Substantiating applicability to mild irritants and non-extractables	8
Comparison of the different protocols of the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) by evaluating the eye irritation potential of surfactants	8
Osthole protects H9c2 cardiomyocytes against trastuzumab-induced damage by enhancing autophagy through the p38MAPK/mTOR signaling pathway	8
The mechanism of anticancer effects of some pyrrolopyrimidine derivatives on HT-29 human colon cancer cells	8
Exploration of structural requirements for azole chemicals towards human aromatase CYP19A1 activity: Classification modeling, structure-activity relationships and read-across study	8
Curcumin from Curcuma longa Linn. (Family: Zingiberaceae) attenuates hypochlorous acid-induced cytotoxicity and oxidative damage to human red blood cells	8
Targeting glioblastoma multiforme using a novel fusion protein comprising interleukin-13 and staphylococcal enterotoxin B in vitro	8
The evaluation of anticancer activity by synthesizing 5FU loaded albumin nanoparticles by exposure to UV light	8
The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine inhibits lipopolysaccharide-induced inflammation transcriptomic pathways and cytokine secretion in a macrophage cell model	8
Propofol inhibits proliferation and migration of glioma cells by up-regulating lncRNA GAS5	8
Potential application of two cobalt (III) Schiff base complexes in cancer chemotherapy: Leads from a study using breast and lung cancer cells	8
E-cigarette fluids and aerosol residues cause oxidative stress and an inflammatory response in human keratinocytes and 3D skin models	8
Polyphenol effects on CuO-nanoparticle-mediated DNA damage, reactive oxygen species generation, and fibroblast cell death	8
Comparative evaluation of HET-CAM and ICE methods for objective assessment of ocular irritation caused by selected pesticide products	8
Silica nanoparticle induces pulmonary fibroblast transdifferentiation via macrophage route: Potential mechanism revealed by proteomic analysis	8
Evaluation of toxicological aspects of three new benzoxazole compounds with sunscreen photophysical properties using in silico and in vitro methods	8
Challenges and opportunities in the use of transcriptomic characterization of human iPSC-derived BBB models	8
Application of in vitro methods to evaluate the safety of baby care products	8
Predicting the binding affinity of chemicals to estrogen receptor using Hansen solubility parameters	8
In vitro toxicological evaluation of a tobacco heating product THP COO and 3R4F research reference cigarette on human lung cancer cells	8
DEHP and DINP accelerate aging effects in male and female of Drosophila melanogaster depend on AKT/FOXO pathway	8
Genotoxic impact of aluminum-containing nanomaterials in human intestinal and hepatic cells	7
Polystyrene nanoparticles incorporate into the endoplasmic reticulum and disturb translation during meiotic maturation in mouse oocytes	7
Accumulated oxidative stress risk in HUVECs by chronic exposure to non-observable acute effect levels of PM2.5	7

A novel co-culture model of human prostate epithelial and stromal cells for androgenic and antiandrogenic screening	7
In vitro investigation of the genotoxicity of portimine, a cyclic imine toxin produced by the dinoflagellate Vulcanodinium rugosum, on human hepatic HepaRG cells	7
Tomentosin induces apoptosis in pancreatic cancer cells through increasing reactive oxygen species and decreasing mitochondrial membrane potential	7
In vitro age-related differences in rats to organophosphates	7
Risk assessment of the inhibition of hydroxygenkwanin on human and rat cytochrome P450 by cocktail method	7
The impact of extractable organic matter from gasoline and alternative fuel emissions on bronchial cell models (BEAS-2B, MucilAir™)	7
In vitro genotoxic and antigenotoxic effects of an exopolysaccharide isolated from Lactobacillus salivarius KC27L	7
Aryl hydrocarbon receptor knockout and antibody blockade of programmed cell death ligand1 increase co-stimulatory molecules on THP-1 and specific cytokine response of human T cells	7
In vitro metabolism of lidocaine in subcellular post-mitochondrial fractions and precision cut slices from cattle liver	7
Akt and MAPK/ERK signaling regulate neurite extension in adult neural progenitor cells but do not directly mediate disruption of cytoskeletal structure and neurite dynamics by low-level silver nanopar	7
(3α)-3-(tiglinoyloxy)-ent-kaur-16-en-19-oic acid, isolated from Wedelia trilobata L., exerts an anti-inflammatory effect via the modulation of NF-κB, MAPK and mTOR pathway and autophagy in LPS-stimula	7
Antimycin A-induced mitochondrial dysfunction is consistent with impaired insulin signaling in cultured skeletal muscle cells	7
In-house performance assessment of 3D QobuR-Reconstructed Human Cornea-Like Epithelium (RhCE) for the evaluation of eye hazard	7
In vitro neurotoxic potential of emerging flame retardants on neuroblastoma cells in an acute exposure scenario	7
Multidirectional anti-melanoma effect of galactolipids (MGDG-1 and DGDG-1) from Impatiens parviflora DC. and their synergy with doxorubicin	7
Tetrazolium–based colorimetric assays underestimat the direct antitumor effects of anti-VEGF agent bevacizumab	7
Toxicological evaluation of fluorescent 11-mercaptoundecanoic gold nanoclusters as promising label-free bioimaging probes in different cancer cell lines	7
Evaluation of the acute toxicity of ellagic acid and gallic acid incorporated in Poloxamer407® gel, in Zophobas morio larvae	6
Editorial Board	6
(-)-Epigallocatechin gallate as an inhibitor of hemoglobin-catalyzed lipid oxidation: molecular mechanism of action and nutritional application	6
Cytochrome P450-mediated metabolic interactions between donepezil and tadalafil in human liver microsomes	6
Substitution of bridge carbons for sulphur in calix[4]arene-bis-α-hydroxymethylphosphonic acid transformed mobile carrier into ionic channel accompanied with evoked muscle contraction and impaired neu	6
Delayed clearance of the pro-carcinogen benzo[a]pyrene in PLHC-1 cells when co-exposed to the antifungal drug clotrimazole and effects on the CYP1A biomarker	6
Interaction between iron oxide nanoparticles (IONs) and primary human immune cells: An up-to-date review of the literature	6
Benzo[b]fluoranthene (B[b]F) affects apoptosis, oxidative stress, mitochondrial membrane potential and expressions of blood-brain barrier markers in microvascular endothelial cells	6
Metformin-suppressed platelet's function in vitro: Possible relation to delayed or failure of platelet-rich fibrin preparation	6
Prediction of skin sensitization using machine learning	6
Hyperoside reduced particulate matter 2.5-induced endoplasmic reticulum stress and senescence in skin cells	6
Modulation of adipogenesis and lipogenesis by indomethacin and pantoprazole	6
Effects of di-(2-ethylhexyl) phthalate and its metabolites on transcriptional activity via human nuclear receptors and gene expression in HepaRG cells	6
Isobavachin induces autophagy-mediated cytotoxicity in AML12 cells via AMPK and PI3K/Akt/mTOR pathways	6
Rubus rosifolius (Rosaceae) stem extract induces cell injury and apoptosis in human hepatoma cell line	6
Perfluorooctanoic acid inhibits cell proliferation through mitochondrial damage	6
In vitro cytotoxicity of six per- and polyfluoroalkyl substances (PFAS) in human immune cell lines	6
Sinapic and ferulic acid phenethyl esters increase the expression of steroidogenic genes in MA-10 tumor Leydig cells	6
Reliability and relevance of the ES®-RHE model for in vitro skin irritation test application	6
Molecular mechanism of di-n-butyl phthalate promotion of bladder cancer development	6
Development of a Defined Approach for Eye hazard identification of chemicals having surfactant properties according to the three UN GHS categories	6
Lipoxin A4 methyl ester attenuated ketamine-induced neurotoxicity in SH-SY5Y cells via regulating leptin pathway	6
Bisphenol S and F affect cell cycle distribution and steroidogenic activity of human ovarian granulosa cells, but not primary granulosa tumour cells	6
The role of efflux transporters in cytotoxicity and intracellular concentration of chlorpyrifos and chlorpyrifos oxon in human cell lines	6
Investigating the mechanisms of action of thyroid disruptors: A multimodal approach that integrates in vitro and metabolomic analysis	6
4-vinylcyclohexene diepoxide induces apoptosis by excessive reactive oxygen species and DNA damage in human ovarian granulosa cells	6
Studies on the interaction of five triazole fungicides with human renal transporters in cells	6
Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro	6
The correlation of haptenation of gold nanoparticles and cysteine modified screen printed carbon electrode by impedance technique with local lymph node assay data	6
Synergistic induction of IL-6 production in human bronchial epithelial cells in vitro by nickel nanoparticles and lipopolysaccharide is mediated by STAT3 and C/EBPβ	6
A comparison of dermal toxicity models; assessing suitability for safe(r)-by-design decision-making and for screening nanomaterial hazards	6
In vitro test methods for evaluating high molecular weight polyethylene oxide polymer induced hemolytic and thrombotic potential	5
Cyclosporin A toxicity on endothelial cells differentiated from induced pluripotent stem cells: Assembling an adverse outcome pathway	5
In vitro differentiation modifies the neurotoxic response of SH-SY5Y cells	5
Donor-to-donor variability of a human three-dimensional bronchial epithelial model: A case study of cigarette smoke exposure	5
Assessment of silver nanoparticles' antitumor effects: Insights into cell number, viability, and morphology of glioblastoma and prostate cancer cells	5
Impact of aerosols on liver xenobiotic metabolism: A comparison of two methods of exposure	5
Conditioned medium of human umbilical cord-mesenchymal stem cells cultivated with human cord blood serum enhances stem cell stemness and secretome profiles	5
Tripartite motif 22 interacts with protein phosphatase magnesium-dependent 1 A to aggravate radiation-induced epithelial-mesenchymal transition and fibrogenesis in lung epithelial cells	5
Comparative in vitro toxicological effects of water-soluble and insoluble components of atmospheric PM2.5 on human lung cells	5
Multiple endpoint in vitro toxicity assessment of a prototype heated tobacco product indicates substantially reduced effects compared to those of combustible cigarette	5
Knockdown of angiopoietin-like 4 suppresses sepsis-induced acute lung injury by blocking the NF-κB pathway activation and hindering macrophage M1 polarization and pyroptosis	5
Deficiency of TRDMT1 impairs exogenous RNA-based response and promotes retrotransposon activity during long-term culture of osteosarcoma cells	5
Sinapic acid alleviates glutamate-induced excitotoxicity by inhibiting neuroinflammation and endoplasmic reticulum stress pathway in C6 glioma cells	5
Evaluation of mitochondrial oxidative toxicity in mammalian cardiomyocytes by determining the highly reproducible and reliable increase in mitochondrial superoxides after exposure to therapeutic drugs	5
An interdisciplinary approach to assessing the toxicity reduction of cerium oxide nanoparticles coated with polyethylene glycol and polyvinylpyrrolidone polymers: An in vitro study	5
Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening	5
Evaluating the combined and individual cytotoxic effect of beauvericin, enniatin B and ochratoxin a on breast cancer cells, leukemia cells, and fresh peripheral blood mononuclear cells	5
Correction to: YAN, a novel microtubule inhibitor, inhibits P-gp and MRP1 function and induces mitotic slippage followed by apoptosis in multidrug-resistant A549/Taxol cells	5
Metabolite of esculetin plays an important role in cytotoxic effects induced by chloroquine on porcine immature Sertoli cells	5
Human vasculature-on-a-chip with macrophage-mediated endothelial activation: The biological effect of aerosol from heated tobacco products on monocyte adhesion	5
Study on percutaneous penetration of representative cosmetic ingredients in a baby wipe product in an in vitro diaper rash skin model	5
Exploring in vitro to in vivo extrapolation for exposure and health impacts of e-cigarette flavor mixtures	5
Machine learning predictive classification models for the carcinogenic activity of activated metabolites derived from aromatic amines and nitroaromatics	5
The effect of prolonged exposure on sodium dodecyl sulfate penetration into human skin	5
Human in vitro percutaneous absorption of bisphenol S: Assessment of the skin reservoir and occlusion effects	5
A microelectric cell sensing technique for in vitro assessment of ocular irritation	5
Involvement of the peroxisome proliferator-activated receptor gamma (Pparγ) and matrix metalloproteinases-2 and -9 (Mmp-2 and -9) in the mechanism of action of di(2-ethylhexyl)phthalate (DEHP) in cult	5
Polyamine-modified naphthalimide derivative 9C inhibits colorectal cancer through ROS-mediated ER stress, migration and invasion	5
Corrigendum to ‘Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach’ [Toxicology in Vitro 68 (2020) 104952]	5
Impacts of high-dose riboflavin on cytotoxicity, antioxidant, growth, reproductive gene expressions, and genotoxicity in the rainbow trout gonadal cells	5
In vitro toxicity of naringin and berberine alone, and encapsulated within PMMA nanoparticles	5
Maximizing the relevance and reproducibility of A549 cell culture using FBS-free media	5
Evaluation of the risk of diarrhea induced by epidermal growth factor receptor tyrosine kinase inhibitors with cultured intestinal stem cells originated from crypts in humans and monkeys	4
A Promising transwell co-culture cell model for silicosis	4
Transcriptional landscape of human keratinocyte models exposed to 60-GHz millimeter-waves	4
Ferulic acid-loaded nanocapsules: Evaluation of mucosal interaction, safety and antioxidant activity in human mononucleated cells	4
Analysis of reproducibility and robustness of OrganoPlate® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs	4
Interaction of mycotoxins zearalenone, α-zearalenol, and β-zearalenol with cytochrome P450 (CYP1A2, 2C9, 2C19, 2D6, and 3A4) enzymes and organic anion transporting polypeptides (OATP1A2, OATP1B1, OATP	4
Inter-laboratory variability of A549 epithelial cells grown under submerged and air-liquid interface conditions	4
Next generation risk assessment (NGRA): Bridging in vitro points-of-departure to human safety assessment using physiologically-based kinetic (PBK) modelling – A case study of doxorubicin with dose met	4
In vitro immunotoxicity effects of carbendazim were inhibited by n-acetylcysteine in microglial BV-2 cells	4
Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells	4
Pyruvate dehydrogenase is a potential mitochondrial off-target for gentamicin based on in silico predictions and in vitro inhibition studies	4
The microRNA miR-152 can mitigate and prevent the toxic effect of benzene on porcine ovarian cells	4
Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system	4
Simulated gastric leachate of 3D printer metal-fill filaments induces cytotoxic effects in rat and human intestinal models	4
Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment	4