Metabolic Brain Disease

Papers
(The TQCC of Metabolic Brain Disease is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Tetramethylpyrazine protects neural stem cells against sevoflurane-induced toxicity through Akt/GSK-3β pathway95
Alzheimer’s disease: a step closer to understanding type 3 diabetes in African Americans88
Knowledge about the characteristics of stroke-like lesions is expandable61
Jobelyn® extends the life span and improves motor function in Drosophila melanogaster exposed to lipopolysaccharide via augmentation of antioxidant status58
Amelioration of intracerebroventricular streptozotocin-induced cognitive dysfunction by Ocimum sanctum L. through the modulation of inflammation and GLP-1 levels52
Clonidine ameliorates cerebral ischemia–reperfusion injury by up-regulating the GluN3 subunits of NMDA receptor51
Retraction Note to: Ocimum basilicum attenuates ethidium bromide-induced cognitive deficits and pre-frontal cortical neuroinflammation, astrogliosis and mitochondrial dysfunction in rats51
The effect of chronic stress and its preconditioning on spatial memory as well as hippocampal LRP1 and RAGE expression in a streptozotocin-induced rat model of Alzheimer’s disease46
Stellate ganglion block suppresses hippocampal ferroptosis to attenuate cerebral ischemia-reperfusion injury via the Hippo pathway42
Inhibition of hyperpolarization-activated cyclic nucleotide-gated cation channel attenuates cerebral ischemia reperfusion-induced impairment of learning and memory by regulating apoptotic pathway42
Anti-inflammatory, anti-apoptotic, and neuroprotective potentials of anethole in Parkinson’s disease-like motor and non-motor symptoms induced by rotenone in rats38
Tramadol induces apoptosis, inflammation, and oxidative stress in rat choroid plexus35
Conditioned medium of human menstrual blood-derived endometrial stem cells protects against cell inflammation and apoptosis of Npc1KO N2a cells34
cAMP/PKA-CREB-BDNF signaling pathway in hippocampus of rats subjected to chemically-induced phenylketonuria33
Clinical features, pathogenesis, and management of stroke-like episodes due to MELAS33
Hesperetin ameliorates diabetes-associated anxiety and depression-like behaviors in rats via activating Nrf2/ARE pathway33
Coadministration of tianeptine alters behavioral parameters and levels of neurotrophins in a chronic model of Maple Syrup Urine disease32
Sevoflurane impedes glioma progression via regulating circ_0000215/miR-1200/NCR3LG1 axis32
Network activity changes in the pathophysiology of Alzheimer’s disease: the role of aging and early entorhinal cortex dysfunction31
MiR-487b suppressed inflammation and neuronal apoptosis in spinal cord injury by targeted Ifitm330
Therapeutic hypothermia for the treatment of neonatal hypoxia-ischemia: sex-dependent modulation of reactive astrogliosis29
Flavonoid-enrich extract of Autranella congolensis (Sapotaceae) protects against aluminium chloride-mediated Alzheimer’s disease-like oxidative stress in rat through the antioxidant properties28
3-Methyladenine ameliorates surgery-induced anxiety-like behaviors in aged mice by inhibiting autophagy-induced excessive oxidative stress27
Deterioration of visual quality and acuity as the first sign of ceroid lipofuscinosis type 3 (CLN3), a rare neurometabolic disease26
Asiatic acid attenuates aluminium chloride-induced behavioral changes, neuronal loss and astrocyte activation in rats26
Paraoxonase 1 status is a major Janus-faced component of mild and moderate acute ischemic stroke and consequent disabilities25
Paeoniflorin ameliorates cognitive impairment in Parkinson’s disease via JNK/p53 signaling24
Complete Loss of Myelin protein zero (MPZ) in a patient with a late onset Charcot-Marie-Tooth (CMT)24
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis24
Necroptosis in the developing brain: role in neurodevelopmental disorders24
Retraction Note: Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Al24
Hepatic glycogen participates in the regulation of hypothalamic pAkt/Akt ratio in high-sugar/high-fat diet-induced obesity24
Identification of methylation markers for diagnosis of autism spectrum disorder24
Differential involvement of hippocampal subfields in Niemann-Pick type C disease: a case–control study24
Correction to: Toxicity of ayahuasca after 28 days daily exposure and effects on monoamines and brain-derived neurotrophic factor (BDNF) in brain of Wistar rats23
Unravelling the potential neuroprotective facets of erythropoietin for the treatment of Alzheimer’s disease23
Neuroprotective effects of carvacrol against cadmium-induced neurotoxicity in rats: role of oxidative stress, inflammation and apoptosis22
Decrypting the cellular and molecular intricacies associated with COVID-19-induced chronic pain21
Transient neonatal hyperglycemia induces metabolic shifts in the rat hippocampus: a 1H NMR-based metabolomics analysis20
Quercetin mitigates scopolamine-induced memory dysfunction: impact on oxidative stress and cholinergic mechanisms20
A pilot study on glutamate receptor and carrier gene variants and risk of childhood autism spectrum20
Neuroprotective effects of methyl jasmonate in male Wistar rats exposed to delayed acetic acid-induced ulcerative colitis: involvement of antioxidant status, GFAP, and IBA-1 immunoreactivities20
Association between MAP3K4 gene polymorphisms and the risk of schizophrenia susceptibility in a Northeast Chinese Han population19
Anti-apoptotic capacity of MALAT1 on hippocampal neurons correlates with CASP3 DNA methylation in a mouse model of autism19
Crosstalk between Alzheimer’s disease and diabetes: a focus on anti-diabetic drugs19
Multimodal MRI in Leigh syndrome due to m.13513G > A19
Adenosine protects D-galactose induced alterations in rat model of aging via attenuating neurochemical profile and redox status18
Exposure to leucine alters glutamate levels and leads to memory and social impairment in zebrafish18
The association of stem cell factor and soluble c-Kit (s-cKit) receptor serum concentrations with the severity and risk prediction of autism spectrum disorders18
Therapeutic potential of endoplasmic reticulum stress inhibitors in the treatment of diabetic peripheral neuropathy18
Correction to: Necrostatin-1 S mitigates type-2 diabetes-associated cognitive decrement and lipotoxicity-induced neuro-microglia changes through p-RIPK-RIPK3-p-MLKL axis18
Stem cell therapy combined with luteolin alleviates experimental neuropathy18
The effect of salmon calcitonin against glutamate-induced cytotoxicity in the C6 cell line and the roles the inflammatory and nitric oxide pathways play18
Estrogen signaling via estrogen receptor alpha and its implications for neurodegeneration associated with Alzheimer’s disease in aging women18
Correction to: Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway18
Peripheral viral challenge increases c-fos level in cerebral neurons18
A rare cause of hydrops fetalis in two Gaucher disease type 2 patients with a novel mutation18
Effects of physical exercise on memory in type 2 diabetes: a brief review18
Correction to: Methylphenidate disrupts cytoskeletal homeostasis and reduces membrane-associated lipid content in juvenile rat hippocampus17
Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma17
Association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene polymorphism with obesity and lipid metabolism in children and adolescents with autism spectrum disorder17
1-benzoyl-6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline exerts a neuroprotective effect and normalises redox homeostasis in a rat model of cerebral ischemia/reperfusion17
RETRACTED ARTICLE: Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (17
Astragalin alleviates cognitive deficits and neuronal damage in SAMP8 mice through upregulating estrogen receptor expression17
Inhibition of γH2AX, COX-2 and regulation of antioxidant enzymes in MPP+-exposed SH-SY5Y cells pre-treated with rutin17
The role of brain inflammation and abnormal brain oxygen homeostasis in the development of hepatic encephalopathy17
Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease17
Associations between GRM7 polymorphisms and obesity in patients selected for sleeve gastrectomy17
miR-181a targets PTEN to mediate the neuronal injury caused by oxygen-glucose deprivation and reoxygenation16
Gossypetin- based therapeutics for cognitive dysfunction in chronic unpredictable stress- exposed mice16
Proteomic advance of ischemic stroke: preclinical, clinical, and intervention16
J-difference GABA-edited MRS reveals altered cerebello-thalamo-cortical metabolism in patients with hepatic encephalopathy16
Convergent molecular mechanisms underlying cognitive impairment in mucopolysaccharidosis type II16
Acute effects of intracerebroventricular administration of α-ketoisocaproic acid in young rats on inflammatory parameters16
Impaired mitochondrial functions and energy metabolism in MPTP-induced Parkinson’s disease: comparison of mice strains and dose regimens15
Activation of BDNF- and VEGF-mediated Neuroprotection by Treadmill Exercise Training in Experimental Stroke15
Psychometric methods for diagnosing and monitoring minimal hepatic encephalopathy —current validation level and practical use15
Curcumin-resveratrol nano-formulation counteracting hyperammonemia in rats15
Therapeutic approaches employing natural compounds and derivatives for treating bipolar disorder: emphasis on experimental models of the manic phase15
Predicting which patients with cirrhosis will develop overt hepatic encephalopathy: Beyond psychometric testing15
Mesenchymal stem cell therapies for Alzheimer’s disease: preclinical studies15
Profiles of urine and blood metabolomics in autism spectrum disorders15
Circular RNA circ_0079593 facilitates glioma development via modulating miR-324-5p/XBP1 axis15
Functional SLC6A3 polymorphisms differentially affect autism spectrum disorder severity: a study on Indian subjects15
MEG3 lncRNA is over-expressed in autism spectrum disorder14
Neuroinflammatory responses following zinc or branched-chain amino acids supplementation in obese rats14
A novel homozygous PIGO mutation associated with severe infantile epileptic encephalopathy, profound developmental delay and psychomotor retardation: structural and 3D modelling investigations and gen14
Neuroprotective effect of green and roasted coffee bean extracts on cerebral ischemia-induced injury in rats14
Nanoselenium improved learning, memory, and brain-derived neurotrophic factor and attenuated nitric oxide, and oxidative stress in the brain of juvenile hypothyroid rats14
A single injection of pregabalin induces short- and long-term beneficial effects on fear memory and anxiety-like behavior in rats with experimental type-1 diabetes mellitus14
Cerebrolysin reduces excitotoxicity by modulation of cell-death proteins in delayed hours of ischemic reperfusion injury14
LPS-induced impairment of Na+/K+-ATPase activity: ameliorative effect of tannic acid in mice14
Hsa_circ_0001361 facilitates cell progression and glycolytic metabolism in neuroblastoma via interacting with mir-490-5p to induce TRIM2 upregulation14
p-Coumaric acid protects against D-galactose induced neurotoxicity by attenuating neuroinflammation and apoptosis in mice brain14
Kif15 deficiency contributes to depression-like behavior in mice14
Effects of omega-3 fatty acid supplementation during chronic maternal hypoxia on behavioral disorders in male rat offspring: the role of Trk family and oxidative stress13
Experimental evidence of tyrosine neurotoxicity: focus on mitochondrial dysfunction13
Ketamine, but not fluoxetine, rapidly rescues corticosterone-induced impairments on glucocorticoid receptor and dendritic branching in the hippocampus of mice13
Withania coagulans extract attenuates oxidative stress-mediated apoptosis of cerebellar purkinje neurons after ischemia/reperfusion injury13
AMPK-dependent autophagy activation and alpha-Synuclein clearance: a putative mechanism behind alpha-mangostin’s neuroprotection in a rotenone-induced mouse model of Parkinson’s disease13
Ferrous sulfate reverses cerebral metabolic abnormality induced by minimal hepatic encephalopathy13
Icariin enhance mild hypothermia-induced neuroprotection via inhibiting the activation of NF-κB in experimental ischemic stroke13
EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR13
Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat13
Sevoflurane represses the progression of glioma by the regulation of circ_0037655/miR-130a-5p/RPN2 axis13
Effect of curcumin nanoparticles on streptozotocin-induced male Wistar rat model of Alzheimer’s disease13
Adiponectin: a potential target for obesity-associated Alzheimer’s disease13
Cannabidiol promotes neurogenesis in the dentate gyrus during an abstinence period in rats following chronic exposure to methamphetamine13
Flavonoids modulate AMPK/PGC-1α and interconnected pathways toward potential neuroprotective activities13
Assessing the Evolution of Intracranial Hematomas by using Animal Models: A Review of the Progress and the Challenges13
Exercise training ameliorates cognitive dysfunction in amyloid beta-injected rat model: possible mechanisms of Angiostatin/VEGF signaling13
Peripheral blood and urine metabolites and biological functions in post-stroke depression13
Circ_0003611 acts as a miR-885-5p sponge to aggravate the amyloid-β-induced neuronal injury in Alzheimer’s disease13
Albumin therapy for hepatic encephalopathy: current evidence and controversies13
Airway inflammation induces anxiety-like behavior through neuroinflammatory, neurochemical, and neurometabolic changes in an allergic asthma model12
Immune-microbiome interplay and its implications in neurodegenerative disorders12
A multi-parameter evaluation of the neuroprotective and cognitive-enhancing effects of Origanum onites L. (Turkish Oregano) essential oil on scopolamine-induced amnestic rats12
Captopril exhibits protective effects through anti-inflammatory and anti-apoptotic pathways against hydrogen peroxide-induced oxidative stress in C6 glioma cells12
Potential of nobiletin against Alzheimer’s disease through inhibiting neuroinflammation12
miR-188-5p silencing improves cerebral ischemia/reperfusion injury by targeting Lin28a12
p53 inhibits the Urea cycle and represses polyamine biosynthesis in glioma cell lines12
Regulation of oxygen–glucose deprivation/reperfusion-induced inflammatory responses and M1-M2 phenotype switch of BV2 microglia by lobetyolin12
Association between lncRNA genetic variants and susceptibility to large artery atherosclerotic stroke12
Impaired ion homeostasis as a possible associate factor in mucopolysaccharidosis pathogenesis: transcriptomic, cellular and animal studies12
Alzheimer’s disease therapy based on acetylcholinesterase inhibitor/blocker effects on voltage-gated potassium channels12
Irisin attenuates ethanol-induced behavioral deficits in mice through activation of Nrf2 and inhibition of NF-κB pathways12
Protective effect of Juglanin against doxorubicin-induced cognitive impairment in rats: Effect on oxidative, inflammatory and apoptotic machineries12
Pseudoephedrine hydrochloride causes hyperactivity in zebrafish via modulation of the serotonin pathway11
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson’s disease11
Ketamine exerts dual effects on the apoptosis of primary cultured hippocampal neurons from fetal rats in vitro11
RNA-seq analysis of ischemia stroke and normal brain in a tree shrew model with or without type 2 diabetes mellitus11
Dysregulation of genes coding for proteins involved in metabolic processes in mucopolysaccharidoses, evidenced by a transcriptomic approach11
Circular RNA circ_0021001 regulates miR-148b-3p/GREM1 axis to modulate proliferation and apoptosis of vascular smooth muscle cells11
A novel LINC00943/miR-671-5p/ELAVL1 ceRNA crosstalk regulates MPP+ toxicity in SK-N-SH cells11
Pathology and prevention of brain microvascular and neuronal dysfunction induced by a high-fructose diet in rats11
PERK inhibitor, GSK2606414, ameliorates neuropathological damage, memory and motor functional impairments in cerebral ischemia via PERK/p-eIF2ɑ/ATF4/CHOP signaling11
Neurological monitoring and sedation protocols in the Liver Intensive Care Unit11
METTL7B contributes to the malignant progression of glioblastoma by inhibiting EGR1 expression11
Reserpine-induced altered neuro-behavioral, biochemical and histopathological assessments prevent by enhanced antioxidant defence system of thymoquinone in mice11
Role of long noncoding RNAs; BDNF-AS and 17A and their relation to GABAergic dysfunction in Egyptian epileptic patients11
D-beta-hydroxybutyrate protects against microglial activation in lipopolysaccharide-treated mice and BV-2 cells11
A novel protein truncating mutation in L2HGDH causes L-2-hydroxyglutaric aciduria in a consanguineous Pakistani family11
Retraction Note to: Long non-coding RNA SNHG7 upregulates FGF9 to alleviate oxygen and glucose deprivation-induced neuron cell injury in a miR-134-5p-dependent manner11
Drug delivery for neuronopathic lysosomal storage diseases: evolving roles of the blood brain barrier and cerebrospinal fluid11
Deregulation of NF-κB associated long non-coding RNAs in bipolar disorder11
Correction to: A multi-parameter evaluation of the neuroprotective and cognitive-enhancing effects of Origanum onites L. (Turkish Oregano) essential oil on scopolamine-induced amnestic rats11
Therapeutic potential of probiotics – Lactobacillus plantarum UBLP40 and Bacillus clausii UBBC07 on thioacetamide-induced acute hepatic encephalopathy in rats11
Changes in activity of µ- and m-calpains and signs of neuroinflammation in the hippocampus and striatum of rats after single intraperitoneal injection of subseptic dose of endotoxin11
Disorders of Tetrahydrobiopterin Metabolism: Experience from South India11
White matter abnormalities and iron deposition in prenatal mucolipidosis IV- fetal imaging and pathology11
Retraction Note to: Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons11
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