OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
The Non-Invasive Transcranial Doppler for Hemodynamic Monitoring	42
Molecular Genetic Aspects of Sporadic Multiglandular Primary Hyperparathyroidism	32
Contralateral and Ipsilateral Arterial Vasculature of the Human Uterus: The Pilot Results of an Anatomical Study	32
Pharmacological Inhibition of eIF2α Phosphorylation by Integrated Stress Response Inhibitor (ISRIB) Ameliorates Vascular Calcification in Rats	30
Network Pharmacological Prediction and Experimental Analyses Reveal That Naringin Alleviates Osteoarthritis Progression by Targeting MMP13	28
Cardiometabolic Parameters and Transcription Factors in Rat Models of Prehypertension With or Without Hypertriglyceridemia: Focus on NRF2 and PPARα Gene Expression	27
Prediction of Akute Kidney Injury Development in Critically Ill Septic Patients Based on NGAL Determination	26
GPER-1 Rapid Regulation Influences p-Akt Expression to Resist Stress-Induced Injuries in a Sex-Specific Manner	24
Roles of Isometric Contraction Training in Promoting Neuroprotection and Angiogenesis After Stroke in Adult Rats	23
Electroacupuncture Stimulation Alleviates Inflammatory Pain in Male Rats by Suppressing Oxidative Stress	23
Vitamin D Levels During Fracture Healing in Children	22
Comparative Analysis of Matrix Metalloproteinases by Zymography in Patients With Colorectal Carcinoma	21
Effects of Astaxanthin on Chronic Exercise Fatigue	20
Assessment of the Cardiovascular Risk of High-Fat-High-Fructose Diet in Hereditary Hypertriacylglycerolemic Rats and Venlafaxine Effect	19
Multi-Frequency Bioimpedance Analysis in Practice: A Review of Validated Prediction Equations for Key Body Composition Parameters	19
Our First Experience Implementing “Clinical Embryology and Reproductive Medicine” as a Curriculum Course of the Study Program General Medicine at the Faculty of Medicine in Bratislava, Slovakia	19
Serum Glutathione and Malondialdehyde Levels as Predictors of Early Neurological Deficits and Short-Term Outcomes in Acute Cerebral Infarction	19
The Role of Cornichons in the Biogenesis and Functioning of Monovalent-Cation Transport Systems	18
Steroid Conjugates and Their Physiological Role	17
Jaroslava Folbergrová, Dr.Sc. (1932 – 2024)	17
RPS3 Aggravates Sepsis-Induced Acute Kidney Injury Through Activating NF-κB Mediated Renal Inflammatory Responses	17
Ellagic Acid Attenuates Muscle Atrophy in STZ-Induced Diabetic Mice	16
	16
Cellular and Molecular Connections Between Bone Fracture Healing and Exosomes	16
The Relationship Between Hormonal Contraceptives, Level of Anxiety and Emotional Awareness: Pilot Project	16

Low Energy Availability and Its Impact on Bone Health and Metabolism in Athletes: A Narrative Review	15
Effects of Hindlimb Suspension on the Development of Hip Bone Morphologies in Growing Rats	15
The impact of atrial fibrillation and atrial tachycardias on the hemodynamic status of patients with pulmonary hypertension	14
Mitochondrial Dysfunction in Kidney Cortex and Medulla of Subtotally Nephrectomized Rat	14
Capsaicin-Assessed Cough Reflex in Asthma Patients	14
Intraventricular Spring Expander Attenuates Cardiac Atrophy of the Failing Heart After Unloading Caused by Heterotopic Heart Transplantation: No Sex-Linked Differences	13
The Temporal and Spatial Effects of Reconstructive Surgery on the Atrophy of Hindlimb Muscles in Anterior Cruciate Ligament Transected Rats	13
Night-to-Day Ratio Specified by 24-hour Blood Pressure Monitoring, Arterial Stiffness and Cardio-Ankle Vascular Index as Predictive Factors of Cardiovascular Risk	13
Can Buckwheat Affect Health and Female Reproductive Functions?	13
Modulation of Cardiac Gene Expression by anti-HMGB1 in a Model of Experimental Myocardial Infarction	13
Inflammation and Fibrosis Induced by Joint Remobilization, and Relevance to Progression of Arthrogenic Joint Contracture: A Narrative Review	13
Post-Operative Atrial Fibrillation: Novel Predictive Value of CT-Derived Adipose Tissue Density in Minimally Invasive Mitral Surgery	13
Direct Effects of Waterpipe Smoke Extract on Aortic Endothelial Cells: An In Vitro Study	12
Curcumin in vitro Neuroprotective Effects Are Mediated by p62/keap-1/Nrf2 and PI3K/AKT Signaling Pathway and Autophagy Inhibition	12
Postprandial Triglyceride, Glucose and Insulin Levels 10 Years After Bariatric Surgery in Women With Severe Obesity – A Pilot Study: Part 1 – Laparoscopic Greater Curvature Plication	12
Distinct Cardiac Connexin-43 Expression in Hypertrophied and Atrophied Myocardium May Impact the Vulnerability of the Heart to Malignant Arrhythmias. A Pilot Study	12
Predictive Value of Serum 25-Hydroxyvitamin D Levels in the Onset and Glycemic Control of Gestational Diabetes Mellitus	11
Influence of Blood Pressure and Heart Rate on PWV Measurement: Assessment Under Real-Time Blood Pressure Monitoring	11
Serum Vitamin D Level in Overweight Individuals and Its Correlation With the Incidence of Non-alcoholic Fatty Liver Disease	11
Connexin 43 in Pathophysiology of Cardiac Diseases: From Molecular Mechanisms to Therapeutic Strategies	11
Dissociation Between the Epileptogenic Lesion and Primary Seizure Onset Zone in the Tetanus Toxin Model of Temporal Lobe Epilepsy	11
Sex differences in blood pressure, free radicals and plasma cholesterol fractions in Ren-2 transgenic rats of various ages	11
Neurophysiological Assessment of H-Reflex Alterations in Compressive Radiculopathy	10
Novel Predictors of Preeclampsia and Pregnancy Complications: the Impact of Type 1 Diabetes Mellitus on Maternal and Fetal Circulatory Levels	10
Circadian Disruption as a Risk Factor for Development of Cardiovascular and Metabolic Disorders – From Animal Models to Human Population	10
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting	10
Endurance Exercise Attenuates Plasma Level of Neurofilament Light Chain and Prevents Body Weight Loss in a Rat Model of Tauopathy	10
Correlation Analysis of Serum 25-Hydroxyvitamin D Levels With Immune Function and Calcium-Phosphate Metabolism in Patients With Bronchial Asthma Treated With Combination Therapy	10
First Application of Whole Genome Sequencing in Myelinated Retinal Nerve Fibers (MRNF)	10
Epilepsy Research in the Institute of Physiology of the Czech Academy of Sciences in Prague	10
Anti-Müllerian Hormone Can Help With Predicting Ovarian Failure for Premenopausal Women Who Have Undergone Ablative Radioiodine Treatment for Thyroid Cancer	10
Role of 5-HT2 Receptors Family in the Allergy-Induced Increased Aorta Contractile Responses to 5-HT	10
Sexual Dimorphism in Plantar Pressure Distribution Patterns	9
Pelargonidin inhibits isoproterenol induced myocardial fibrosis via regulating transforming growth factor-β/Smad2/3 signaling and Th2 cytokines in mice	9
Trunk Impairment Scale and Stroke Impact Scale for Clinical Assessment of Patients in the Subacute Stage After Stroke Following Sensory Intervention	9
The Effect of Sulforaphane on Perinatal Hypoxic-Ischemic Brain Injury in Rats	9
History of Blood Pressure Measurement in Newborns and Infants	9
The Effect of Bariatric-Metabolic Surgery on Selected Components of Metabolic Syndrome and Visceral Adipose Tissue – The Pilot Study	9
Waterpipe Smoke Inhalation Induces Lung Injury and Aortic Endothelial Dysfunction in Mice	9
ASIC1a Involves the Acid-Mediated Activation of Pancreatic Stellate Cells Associated With Autophagy Induction	9
Rho-Kinase Inhibition Ameliorates Non-Alcoholic Fatty Liver Disease in Type 2 Diabetic Rats	9
Cardiorenal Syndromes and Their Role in Water and Sodium Homeostasis	9
Adaptive Induction of Nonshivering Thermogenesis in Muscle Rather Than Brown Fat Could Counteract Obesity	8
Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4	8
Comparison of Pulse Wave Arrival Times Measured by Bioimpedance Method and Doppler Ultrasound	8
Altered Balance between Vasoconstrictor and Vasodilator Systems in Experimental Hypertension	8
Cholesterol efflux and macrophage polarization in human adipose tissue	8
Experimental Lung Transplantation Related With HIF-1, VEGF, ROS. Assessment of HIF-1α, VEGF, and Reactive Oxygen Species After Competitive Blockade of Chetomin for Lung Transplantation in Rats	8
Bioelectrical Impedance in Monitoring Hyperhydration and Muscle Wasting in Critically Ill Corona Virus Disease (COVID-19) Patients: The Feasibility of Predicting Outcome	8
Unusual Functions of Insect Vitellogenins: Minireview	8

Ten Years of Our Translational Research in the Field of Veno-Arterial Extracorporeal Membrane Oxygenation	8
PAR2: The Cornerstone of Pancreatic Diseases	8
The Effect of Dietary Oat Consumption and Its Constituents on Fat Storage and Obesity	8
Effect of Carvacrol on Diabetes-Induced Oxidative Stress, Fibrosis and Apoptosis in Testicular Tissues of Adult Rats	8
Gut Hormone Levels During Mixed Liquid Meal Test in Short Bowel Syndrome, the Possible Influence on the Intestine Adaptation	7
Baicalin Ameliorates Cartilage Injury in Rats With Osteoarthritis via Modulating miR-766-3p/AIFM1 Axis	7
The Role of L-Cysteine/H2S Pathway in CaSRs-Mediated Relaxations in Mouse Bladder Tissue	7
Steroidogenic Enzyme Gene Expression and Testosterone Production are Developmentally Modulated by Bone Morphogenetic Protein Receptor-1B in Mouse Testis	7
Is there a Need to Change the Basic Principles of Histology? Educational, Functional and Embryological Perspective	7
Nutrition and Bone Marrow Adiposity in Relation to Bone Health	7
Iodine Intake and Iodine Status in the Czech Republic – Past, Present, Future	7
Chronic Venous Disease and Its Intersections With Diabetes Mellitus	7
Surgery and Acute Stress Decrease NRF2 mRNA Expression and Promote Iron Metabolism Alteration, Oxidative Stress, and Inflammatory Gene Expression in the Liver of Prehypertensive Rats	7
NADPH oxidase 4 contributes to oxidative stress in a mouse model of myocardial infarction	7
Inhibition of Extracellular Signal-Regulated Kinase Downregulates Endoplasmic Reticulum Stress-Induced Apoptosis and Decreases Brain Injury in a Cardiac Arrest Rat Model	7
From a Passive Conduit to Highly Dynamic Organ. What are the Roles of Uterine Tube Epithelium in Reproduction?	7
Colored Light Exposure Ensues Chronotype-Based Responses: Evidence From QEEG Analysis	7
Effects of Isovolumic Loading Elicited Either by 3-Branch or by 4-Branch Spring Expander on the Degree of Cardiac Atrophy of the Failing Heart in Rats After Heterotopic Heart Transplantation: No Evide	7
Impact of Bariatric Surgery Type on Adipokines, Myokines, and Hepatokines: An 18-Month Prospective, Observational, Open-Label Study	7
Analysis of Gene Expression Profiles Regulating Phenotypic Transformation of Vascular Smooth Muscle Cells by Endothelial Cell-Derived Exosomes	6
Altered Plasma Butyrylcholinesterase Activity in Streptozotocin-Induced Diabetic Hypertensive Rats Does Not Reflect Impaired Liver Function	6
Berberine Exerts Neuroprotective Effects in Alzheimer’s Disease by Switching Microglia M1/M2 Polarization Through PI3K-AKT Signaling	6
Phase Angle in Bioelectrical Impedance: New Perspectives in Health and Body Composition Assessment	6
Targeting the Toll-Like Receptor 4 Ameliorates Heart Failure in Aged Mice by Inhibiting the Formation of Neutrophil Extracellular Traps	6
Postprandial Triglyceride, Glucose and Insulin Levels 10 Years After Bariatric Surgery in Women With Severe Obesity – A Pilot Study: Part 2 – Biliopancreatic Diversion	6
Nitric Oxide Synthase Expression in Endometrium During Physiological Cycle	6
Decellularization techniques of human foreskin for tissue engineering application	6
Cardiovascular Changes During Phototherapy in Newborns	6
Modern Perspective of Lactate Metabolism	6
Eicosapentaenoic Acid Alleviates Inflammatory Response and Insulin Resistance in Pregnant Mice With Gestational Diabetes Mellitus	6
The role of renal Na+/H+ exchange in the regulation of acid-base and sodium homeostasis in premature infants	6
Sixty Years of Heart Research in the Institute of Physiology of the Czech Academy of Sciences	6
Potential Effect of Trigonella Microgreens on Functional Parameters of HUVEC Cells in vitro	6
Aspalathin Alleviates Skeletal Muscle Insulin Resistance and Mitochondrial Dysfunction	6
Bruton’s Tyrosine Kinase: A Potential Novel Target for Neurological Disorders	6
Metabolic Syndrome in Hypertriglyceridemic Rats: Effects of Antioxidants	6
Comprehensive Genomic Profiling in Predictive Testing of Cancer	6
Circulating Exosomal miRNAs as a Promising Diagnostic Biomarker in Cancer	6
Impairment of Endogenous H2S Pathway due to Aging and Endothelium Denudation in Mouse Isolated Thoracic Aorta	6
Cerebral Perfusion Pressure and Behavior Monitoring in Freely Moving Rats	5
Interplay Between Astroglial Endocannabinoid System and the Cognitive Dysfunction in Alzheimer's Disease	5
Clinical Efficacy of Blood Ultrafiltration Therapy in Patients with Acute Decompensated Chronic Heart Failure	5
Effect of Laparoscopic Sleeve Gastrectomy on Serum Adipokine Levels	5
Differential Mitochondrial Adaptation of the Slow and Fast Skeletal Muscles by Endurance Running Exercise in Streptozotocin-Induced Diabetic Mice	5
Parvalbumin - Positive Neurons in the Neocortex: A Review	5
Ginsenoside-MC1 Alleviates Stroke by Modulating AMPK/SIRT1 Pathway in a Rat Model	5
Early Uterine Transplant Graft Loss Due to Thrombosis: Single-Center Experience With Causes, Prevention, Diagnosis, and Treatment	5
Linc-ROR Modulates the Endothelial-Mesenchymal Transition of Endothelial Progenitor Cells through the miR-145/Smad3 Signaling Pathway	5
Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation	5
Role of Carvedilol in Inhibiting the Proliferation and Migration of Vascular Smooth Muscle Cells by Upregulating microRNA-145 Expression	5
Cadmium-Induced Hepatotoxicity in Mice – Prophylactic Supplementation of Quercetin Exerts Hepatoprotective Effect by Modulating PI3K/Akt/NF-κB Signaling Pathway	5
Dihydromyricetin Inhibits Ferroptosis to Attenuate Cisplatin-Induced Muscle Atrophy	5
Are Oligodendrocytes the Culprits or Victims in Alzheimer's Disease	5
The Expression Level of Inflammation-Related Genes in Patients With Bone Nonunion and the Effect of BMP-2 Infected Mesenchymal Stem Cells Combined With nHA/PA66 on the Inflammation Level of Femoral Bo	5
Reactivity of Isolated Arteries After 5-Week-Lasting Period of Intermittent Fasting Followed by the Return to Ad Libitum Regimen in Healthy Rats Fed With Normal and High-Fat Diet	5
Mechanisms of Cardiovascular Changes of Phototherapy in Newborns with Hyperbilirubinemia	5
From the Pineal Gland to the Central Clock in the Brain: Beginning of Studies of the Mammalian Biological Rhythms in the Institute of Physiology of the Czech Academy of Sciences	5
Methamphetamine use during the first or second half of pregnancy worsens cardiac ischemic injury in adult female offspring	5
Hydrolat of Helichrysum Italicum promotes tissue regeneration during wound healing	5
Research on Experimental Hypertension in Prague (1966-2009)	5
Ca2+ Depletion in the ER Causes Store-Operated Ca2+ Entry via the TRPC6 Channel in Mouse Brown Adipocytes	5
Effects of total intravenous anesthesia with etomidate and propofol on postoperative cognitive dysfunction	5
Mechanisms Controlling the Behavior of Vascular Smooth Muscle Cells in Hypoxic Pulmonary Hypertension	5
Role of PKM2 Tetramer in Modulating Endothelial Mitochondrial Dysfunction in a Rat Model of Chronic Thromboembolic Pulmonary Hypertension	5
Myocardial Fibrosis, The Silent Instigator of Diastolic Dysfunction in Patients With Rheumatoid Arthritis	5
Low-Level Laser Therapy Attenuates Arthrogenic Contracture Induced by Anterior Cruciate Ligament Reconstruction Surgery in Rats	5