OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The anti-obesity and health-promoting effects of tea and coffee	46
Acute Lung Injury – From Pathophysiology to Treatment	41
CCR5Δ32 Deletion as a Protective Factor in Czech First-Wave COVID-19 Subjects	36
The Role of Skeletal Muscle in The Pathogenesis of Altered Concentrations of Branched-Chain Amino Acids (Valine, Leucine, and Isoleucine) in Liver Cirrhosis, Diabetes, and Other Diseases	32
The Role of AMPK/mTOR Signaling Pathway in Anticancer Activity of Metformin	31
The Role of Nrf2 and PPARγ in the Improvement of Oxidative Stress in Hypertension and Cardiovascular Diseases	29
Hepatic Stellate Cell: A Double-Edged Sword in the Liver	28
Alveolar Type II Cells and Pulmonary Surfactant in COVID-19 Era	27
Role of cytochrome c oxidase nuclear-encoded subunits in health and disease	21
The effects of spaceflight microgravity on the musculoskeletal system of humans and animals, with an emphasis on exercise as a countermeasure: a systematic scoping review	20
The potential applications of artificial intelligence in drug discovery and development	19
Side Effects of Amino Acid Supplements	19
Parathyroid Hormone-Related Changes of Bone Structure	18
Eye pupil – a window into central autonomic regulation via emotional/cognitive processing	17
Aluminum Oxide and Zinc Oxide Induced Nanotoxicity in Rat Brain, Heart, and Lung	16
Coenzyme Q10 effects in neurological diseases	16
Inhibitory Immune Checkpoint Molecules and Exhaustion of T cells in COVID-19	15
Aspiration syndromes and associated lung injury: incidence, pathophysiology and management	15
Electroacupuncture inhibits the interaction between peripheral TRPV1 and P2X3 in rats with different pathological pain	14
Cytokine Cascade in Kawasaki Disease Versus Kawasaki-Like Syndrome	14
MiR-133a-3p Relieves the Oxidative Stress Induced Trophoblast Cell Apoptosis Through the BACH1/Nrf2/HO-1 Signaling Pathway	14
Clinical implications of the glucokinase impaired function – GCK MODY today	14
Methamphetamine, Neurotransmitters and Neurodevelopment	13
COVID-19, Oxidative Stress, and Male Reproductive Dysfunctions: Is Vitamin C a Potential Remedy?	13
Interactions of Renin-Angiotensin System and COVID-19: The Importance of Daily Rhythms in ACE2, ADAM17 and TMPRSS2 Expression	13

Various Aspects of Sex and Gender Bias in Biomedical Research	13
Could the Musk Compound Tonalide Affect Physiological Functions and Act as an Endocrine Disruptor in Rainbow Trout?	12
COVID-19 and the Differences in Physiological Background Between Children and Adults and Their Clinical Consequences	12
The effect of obesity, hypertension, diabetes mellitus, alcohol, and sleep apnea on the risk of atrial fibrillation	11
Plasma asprosin, CCDC80 and ANGPTL4 levels are associated with metabolic and cardiovascular risk in patients with inflammatory bowel disease	11
Phenotype and function of macrophage polarization in monocrotaline-induced pulmonary arterial hypertension rat model	11
Healthy microbiome – a mere idea or a sound concept?	10
Hyperbaric oxygen influences chronic wound healing – a cellular level review	10
Men´s reproductive alterations caused by bisphenol A and its analogues: a review	10
Portal hypertension is the main driver of liver stiffness in advanced liver cirrhosis	10
Pancreatic stellate cells - rising stars in pancreatic pathologies	10
Hydrogen sulfide protects against ischemic heart failure by inhibiting RIP1/RIP3/MLKL-mediated necroptosis	10
Impact of Aging on Mitochondrial Respiration in Various Organs	10
Transient Receptor Potential Ankyrin 1 Channel: An Evolutionarily Tuned Thermosensor	10
Steroids, steroid associated substances and gestational diabetes mellitus	9
Pediatric Inflammatory Multisystem Syndrome (PIMS) – Potential role for cytokines such Is IL-6	9
Alternations in the cardiovascular autonomic regulation and growth factors in autism	9
Mitochondrial Respiration of Human Platelets in Young Adult and Advanced Age – Seahorse or O2k?	9
Current Status of the Applications of Conditioned Media Derived from Mesenchymal Stem Cells for Regenerative Medicine	9
Acellular Dermal Matrix in Plastic and Reconstructive Surgery	9
C-Reactive Protein, Chemerin, Fetuin-A and Osteopontin as Predictors of Cardiovascular Risks in Persons With Psoriasis Vulgaris	9
Sex Steroid Hormones in Depressive Disorders as a Basis for New Potential Treatment Strategies	9
Microbiota of female genital tract – functional overview of microbial flora from vagina to uterine tubes and placenta	9
Introduction to DOK2 and its Potential Role in Cancer	8
Progesterone Inhibitory Role on Gastrointestinal Motility	8
Fluid Shear Stress Promotes Osteoblast Proliferation and Suppresses Mitochondrial-Mediated Osteoblast Apoptosis Through the miR-214-3p-ATF4 Signaling Axis	8
Herbal Compounds in the Treatment of Pulmonary Silicosis	8
“Double-Edged Sword” Effect of Reactive Oxygen Species (ROS) in Tumor Development and Carcinogenesis	8
Dynamic Changes of High-Sensitivity Troponin T Concentration During Infancy: Clinical Implications	8
Effects of Selected Inherited Factors on Susceptibility to SARS-CoV-2 Infection and COVID-19 Progression	8
The effects of different types of exercise on circulating irisin levels in healthy individuals and in people with overweight, metabolic syndrome and type 2 diabetes	8
Riboflavin Recovery of Spermatogenic Dysfunction via a Dual Inhibition of Oxidative Changes and Regulation of the PINK1-Mediated Pathway in Arsenic-Injured Rat Model	8
miR-431-5p Regulates Apoptosis of Cardiomyocytes After Acute Myocardial Infarction via Targeting Selenoprotein T	8
Effects of Concentrated Growth Factor and Nanofat on Aging Skin of Nude Mice Induced by D-Galactose	8
Review of the structural and functional brain changes associated with chronic kidney disease	8
Plant extracellular vesicles and their potential in human health research, the practical approach	7
Study on the Regulation Mechanism of Lipopolysaccharide on Oxidative Stress and Lipid Metabolism of Bovine Mammary Epithelial Cells	7
Functions of Sleep	7
Impact of Prenatal Hypoxia on the Development and Behavior of the Rat Offspring	7
Perinatal Hypoxic-Ischemic Damage: Review of the Current Treatment Possibilities	7
Antioxidative Effect of Dietary Flavonoid Isoquercitrin on Human Ovarian Granulosa Cells HGL5 In Vitro	7
Effect of iron oxide nanoparticles on vascular function and nitric oxide production in acute stress-exposed rats	7
Protection of Toll-Like Receptor 9 Against Lipopolysaccharide-Induced Inflammation and Oxidative Stress of Pulmonary Epithelial Cells via MyD88-Mediated Pathways	6
Uterine Natural Killer Cells in the Context of Implantation: Immunohistochemical Analysis of Endometrial Samples from Women with Habitual Abortion and Recurrent Implantation Failure	6
Anti-inflammatory effect of Irisin on LPS-stimulated macrophages through inhibition of MAPK pathway	6
Cardiovascular Physiology and Pathophysiology in Down Syndrome	6
The Combination of Atorvastatin With Silymarin Enhances Hypolipidemic, Antioxidant and Anti-Inflammatory Effects in a Rat Model of Metabolic Syndrome	6
Low-Level Laser Therapy Attenuates Arthrogenic Contracture Induced by Anterior Cruciate Ligament Reconstruction Surgery in Rats	6
Edaravone Attenuates Disease Severity of Experimental Auto-Immune Encephalomyelitis and Increases Gene Expression of Nrf2 and HO-1	6
Myocardial m6A regulators in postnatal development: effect of sex	6

Sensitivity of Zebrafish (Danio rerio) Embryos to Hospital Effluent Compared to Daphnia magna and Aliivibrio fischeri	6
Treatment With Coenzyme Q10, ω-3-Polyunsaturated Fatty Acids and Their Combination Improved Bioenergetics and Levels of Coenzyme Q9 and Q10 in Skeletal Muscle Mitochondria in Experimental Model of Art	6
Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Myocardial Injury Through TLR4-NLRP3 Pathway	6
Structure-Function Relationships and Modifications of Cardiac Sarcoplasmic Reticulum Ca2+-Transport	6
Pathophysiological Analysis of Uninephrectomized db/db Mice as a Model of Severe Diabetic Kidney Disease	6
Fibroblast Growth Factor 23 and Klotho Are Associated With Trabecular Bone Score but Not Bone Mineral Density in the Early Stages of Chronic Kidney Disease: Results of the Cross-Sectional Study	6
Variability of Peripheral Pulse Wave Velocity in Patients With Diabetes Mellitus Type 2 During Orthostatic Challenge	6
Ovarian Reserve Assessed by the Anti-Mullerian Hormone and Reproductive Health Parameters in Women With Crohn´s Disease, a Case-Control Study	6
Puncture vine (Tribulus Terrestris L.) in control of health and reproduction	6
Electromagnetic Fields - Do They Pose a Cardiovascular Risk?	6
The Long-Term Effects of Growth Hormone Replacement on Bone Mineral Density and Trabecular Bone Score: Results of the 10-Year Prospective Follow-up	6
Parvalbumin - Positive Neurons in the Neocortex: A Review	5
Altered Expression of ORAI and STIM Isoforms in Activated Human Cardiac Fibroblasts	5
Determination of Brain Water Content by Dry/Wet Weight Measurement for the Detection of Experimental Brain Edema	5
Ellagic Acid Attenuates Muscle Atrophy in STZ-Induced Diabetic Mice	5
From a Passive Conduit to Highly Dynamic Organ. What are the Roles of Uterine Tube Epithelium in Reproduction?	5
Pathophysiological Characteristics Linking Type 2 Diabetes Mellitus and Colorectal Neoplasia	5
Effect of Beer Consumption on Methylation and Redox Metabolism	5
MiR-18a Inhibits PI3K/AKT Signaling Pathway to Regulate PDGF BB-Induced Airway Smooth Muscle Cell Proliferation and Phenotypic Transformation	5
Androgens in SARS-CoV-2 Coronavirus Infections	5
Beta-Adrenergic Receptors Gene Polymorphisms are Associated With Cardiac Contractility and Blood Pressure Variability	5
Antisenescence Effect of REAC Biomodulation to Counteract the Evolution of Myelodysplastic Syndrome	5
Aging-induced down-regulation of Pka/Bkca pathway in rat cerebral arteries	5
SARS-CoV-2 Viral Load Assessment in Lung Transplantation	5
The Severity of Muscle Performance Deterioration in Sarcopenia Correlates With Circulating Muscle Tissue-Specific miRNAs	5
Aspiration syndromes and associated lung injury: incidence, pathophysiology and management	5
PAR2: The Cornerstone of Pancreatic Diseases	5
Inhibition of L-NAME-Induced Hypertension by Combined Treatment With Apocynin and Catalase: The Role of Nox 4 Expression	5
Circulating Exosomal miRNAs as a Promising Diagnostic Biomarker in Cancer	5
The effect of Apium Graveolens L., Levisticum Officinale and Calendula Officinalis L. on cell viability, membrane integrity, steroidogenesis, and intercellular communication in mice Leydig cells in vi	5
Role of Cisplatin in Inducing Acute Kidney Injury and Pyroptosis in Mice via the Exosome miR-122/ELAVL1 Regulatory Axis	5
Glucagon-like peptide-1 receptor agonist reduces di(2-ethylhexyl) phthalate-induced atherosclerotic processes in vascular smooth muscle cells	5
Acute and Chronic Effects of High-Intensity Interval Training (HIIT) on Postexercise Intramuscular Lipid Metabolism in Rats	5
Downregulation of long non-coding RNA AIRN promotes mitophagy in alcoholic fatty hepatocytes by promoting ubiquitination of mTOR	4
Valsartan prevented neointimal hyperplasia and inhibited SRSF1 expression and the TLR4–iNOS–ERK–AT1 receptor pathway in the balloon-injured rat aorta	4
Efficacy of Surfactant Therapy of ARDS Induced by Hydrochloric Acid Aspiration Followed by Ventilator-Induced Lung Injury – an Animal Study	4
Effects of total intravenous anesthesia with etomidate and propofol on postoperative cognitive dysfunction	4
Effects of Treadmill Exercise on Sexual Behavior and Reproductive Parameters in Chronically Stressed-Male Rats	4
The Effects of Wheel-Running Using the Upper Limbs Following Immobilization After Inducing Arthritis in the Knees of Rats	4
The Role of Pulmonary Artery Wedge Pressure on the Incidence of Atrial Fibrillation and Atrial Tachycardias in Patients With Isolated Pre-capillary Pulmonary Hypertension	4
Ovarian Steroid Hormone Secretion by Human Granulosa Cells After Supplementation of Sambucus nigra L. Extract	4
Neonatal Hypoxic-Ischemic Brain Injury Leads to Sex-Specific Deficits in Rearing and Climbing in Adult Mice	4
Fennel affects ovarian cell proliferation, apoptosis, and response to ghrelin	4
Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat	4
Resveratrol Attenuates Rheumatoid Arthritis Induce Neutrophil Extracellular Traps via TLR-4 Mediated Inflammation in C57BL/6 Mice	4
MiR-15a-5p Accelerated Vascular Smooth Muscle Cells Viabilities and Migratory Abilities via Targeting Bcl-2	4
Current progress in the therapeutic options for mitochondrial disorders.	4
A Mixture of Diethylhexyl, Diisononyl and Dibutyl Phthalate Decreased Anogenital Distance, Postnatal Testosterone Levels, and Changed Social Behavior in Wistar Rats	4
The Effects of Titanium Topography and Chemical Composition on Human Osteoblast Cell	4
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson’s Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy	4
Combined Effect of Acute Altitude Exposure and Vigorous Exercise on Platelet Activation	4
Molecular Biomarkers of Bladder Cancer: A Mini-Review	4
Complex Sympathetic Regulation in Adolescent Mitral Valve Prolapse	4
Could the CCR5-Δ32 Mutation be Protective in SARS-CoV-2 Infection?	4
Gait Changes Following Robot-Assisted Gait Training in Children With Cerebral Palsy	4
Rescuing Lethal Phenotypes Induced by Disruption of Genes in Mice: a Review of Novel Strategies	4
Rho-Kinase Inhibition Ameliorates Non-Alcoholic Fatty Liver Disease in Type 2 Diabetic Rats	4
JAK2/STAT3 pathway mediates beneficial effects of pterostilbene on cardiac contractile and electrical function in the setting of myocardial reperfusion injury	4
Noninvasive arterial compliance estimation	4
Does Dihydromyricetin Impact on Alcohol Metabolism	4
Early Cardiac Injury in Acute Respiratory Distress Syndrome: Comparison of Two Experimental Models	4
Short-Term Arterial Compliance Changes in the Context of Systolic Blood Pressure Influence	4
Is Apelin a new biomarker in patients with polycystic ovary syndrome?	4
Baroreflex Sensitivity and Blood Pressure in Premature Infants – Dependence on Gestational Age, Postnatal Age and Sex	4
Baicalin Alleviates Silica-Induced Lung Inflammation and Fibrosis by Inhibiting TLR4/NF-κB Pathway in Rats	4