OOIR: Observatory of International Research

Papers

(The median citation count of Biochemistry and Cell Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Interaction between the guanylate kinase domain of PSD-95 and the proline-rich region and microtubule binding repeats 2 and 3 of tau	34
TRAF7 inhibits proliferation and migration of esophageal squamous cell carcinoma by ubiquitination-mediated degradation of SOX12	27
BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance	23
Cadmium chloride generates cytotoxic reactive species that cause oxidative damage and morphological changes in human erythrocytes	21
Retraction: MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN	18
NDUFA4 promotes the progression of head and neck paraganglioma by inhibiting ferroptosis	18
RNA deadenylation complexes in development and diseases	18
CD142 plays a key role in the carcinogenesis of gastric adenocarcinoma by inhibiting BCL2-dependent autophagy	17
GCN5 enables HSP12 induction promoting chromatin remodeling, not histone acetylation	17
Aberrant sphingomyelin ³¹P-NMR signatures in giant cell tumour of bone	17
Computational screening of filamin mechanical binding proteins using AlphaFold2	17
Working from within: how secretory leukocyte protease inhibitor regulates the expression of pro-inflammatory genes	17
Expression of concern: MicroRNA-518-3p suppresses cell proliferation, invasiveness, and migration in colorectal cancer via targeting TRIP4	16
KREMEN2 promotes the proliferation and the metastasis through activating PI3K/AKT/mTOR signaling pathway in non-small cell lung cancer	16
Perturbation of calcium homeostasis invokes eryptosis-like cell death in enucleated bone marrow stem cells	15
Retraction: MiR-1180 promotes cardiomyocyte cell cycle re-entry after injury through the NKIRAS2–NFκB pathway	15
Antibiofilm activities of lactoferricin-related Trp- and Arg-rich antimicrobial hexapeptides against pathogenic Staphylococcus aureus and Pseudomonas aeruginosa strains	14
WDR4 promotes colorectal cancer progression by activating the GSK3β/β-catenin pathway	14
Lipid-induced alteration in retinoic acid signaling leads to mitochondrial dysfunction in HepG2 and Huh7 cells	13
ChestCovidNet: An Effective DL-based Approach for COVID-19, Lung Opacity, and Pneumonia Detection Using Chest Radiographs Images	13
Distinct domain organization and diversity of 2′-5′-oligoadenylate synthetases	13
HDAC1 overexpression promoted by METTL3-IGF2BP2 inhibits FGF21 expression in metabolic syndrome-related liver injury	13
Bone marrow granulocytes downregulate IL-1β and TNF production and the microbicidal activity of inflammatory macrophages	12
Correction: Ultrasound-stimulated microbubbles contributes to radiotherapy in esophageal carcinoma	12
GCN5 regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement	12

MTHFD2 suppresses glioblastoma progression via the inhibition of ERK1/2 phosphorylation	11
Bovine lactoferrin suppresses the proliferation of endometriotic stromal cells via the PI3K/Akt/mTOR pathway	11
Unveiling stem-like traits and chemoresistance mechanisms in ovarian cancer cells through the TGFβ1-PITX2A/B signaling axis	11
RNF38 inhibits osteosarcoma cell proliferation by binding to CRY1	11
Synergistic inhibitory effects of 5-aza-2′-deoxycytidine and cisplatin on urothelial carcinoma growth via suppression of TGFBI-MAPK signaling pathways	11
Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing JAK1/STAT1 pathway	11
WWP2 binds to NKRF, enhances the NF-κB signaling, and promotes malignant phenotypes of acute myeloid leukemia cells	10
Small proline-rich protein 1A promotes lung adenocarcinoma progression and indicates unfavorable clinical outcomes	10
Characterization of cells expressing lipocalin-2 (LCN2) as a reporter	10
MCPIP1 deficiency alleviates abdominal aortic aneurysm formation by inhibiting MAPK signaling	9
O-GlcNAcylation of epidermal growth factor receptor and glucose transporter 1 prevents their intrinsic down regulation in breast cancer cells	9
Establishment of immortalized porcine intramuscular preadipocytes for the study of lipid metabolism	9
Isovitexin attenuates tumor growth in human colon cancer cells through the modulation of apoptosis and epithelial-mesenchymal transition via PI3K/Akt/mTOR signaling pathway	9
Structure-based design of small molecule inhibitors of the cagT4SS ATPase Cagα of Helicobacter pylori	9
Antibacterial, anti-invasive, and anti-inflammatory activity of bovine lactoferrin extracted from milk or colostrum versus whole colostrum	8
How to become a successful scientist: the 2022 CSMB Arthur Wynne Gold Medal Lecture	8
Study on the mechanism of USP7 promoting endometriosis by regulating DNMT1 deubiquitination level	8
Evaluation of biochemical profile and oxidative damage to lipids and proteins in patients with lysosomal acid lipase deficiency	8
18^th International Conference of Biochemistry & Molecular Biology (18^th ICBMB)	8
Structural features, intrinsic disorder, and modularity of a pyriform spidroin 1 core repetitive domain	8
Subacute exposure to aluminium chloride induces cytotoxicity and oxidative stress in rat erythrocytes: A dose-dependent study	8
Neuroprotective effects of whey and buttermilk-based formulas on a DSS-induced colitis murine model	8
Correction: Protective effect of nitronyl nitroxide against hypoxia-induced damage in PC12 cells	8
Substitution of histone H3 arginine 72 to alanine leads to the deregulation of isoleucine biosynthesis in the budding yeast Saccharomyces cerevisiae	8
Suppression of academics and school training in Iran during the “Woman, Life, Freedom” revolution	8
RNA-binding protein NOVA1 promotes acute T-lymphocyte leukemia progression by stabilizing USP44 mRNA	8
A role for NFIB in SOX2 downregulation and epigenome accessibility changes due to long-term estrogen treatment of breast cancer epithelial cells	7
LMAN2 interacts with HEATR3 to expedite HER2-positive breast cancer advancement and inflammation and Akt/ERK/NF-κB signaling	7
S-allylcysteine inhibits chondrocyte inflammation to reduce human osteoarthritis via targeting RAGE, TLR4, JNK, and Nrf2 signaling: comparison with colchicine	7
Effects of different sources of lactoferrin on cytokine response to SARS-COV-2, respiratory syncytial virus, and rotavirus infection in vitro	7
Neurodevelopmental functions and activities of the KAT3 class of lysine acetyltransferases	7
Recombinant human holo-lactoferrin in complex with oleic acid suppresses the growth of solid myeloma more efficiently than its apo-form	7
Retraction: MiR-204 suppresses cell proliferation and promotes apoptosis in ovarian granulosa cells via targeting TPT1 in polycystic ovary syndrome	7
Hoxa5 inhibits adipocyte proliferation through transcriptional regulation of Ccne1 and blocking JAK2/STAT3 signaling pathway in mice	6
FYCO1 regulates migration, invasion, and invadopodia formation in HeLa cells through CDC42/N-WASP/Arp2/3 signaling pathway	6
Structure and function of fermentation-derived bovine lactoferrin produced from Komagataella phaffii	6
Note of appreciation	6
The regulation of m⁶A-related proteins during whole-body freezing of the freeze-tolerant wood frog	6
Effects of clopidogrel bisulfate on B16-F10 cells and tumor development in a murine model of melanoma	6
Doxorubicin, a DNA intercalator, inhibits transcription elongation	6
Decreased NMIIA heavy chain phosphorylation at S1943 promotes mitoxantrone resistance by upregulating BCRP and N-cadherin expression in breast cancer cells	6
Cell-in-cell-mediated intercellular communication exacerbates the pro-inflammatory progression in asthma	6
Chelerythrine alleviates inflammation and angiogenesis in a mouse rosacea model via suppressing the NF-κB/p38 MAPK/STAT3 pathways	6
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease	6
Hydrocortisone improves post-resuscitation myocardial dysfunction by inhibiting the NF-κB pathway	6
Retraction: Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells	6
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin	6
LINC00641 contributes to nasopharyngeal carcinoma cell malignancy through FOXD1 upregulation at the post-transcriptional level	5
A combinatorial multi-site directed mutagenesis solution for improved thermal stability of Lactobacillus plantarum tannase	5
Retraction: Role of the TSLP–DC–OX40L pathway in asthma pathogenesis and airway inflammation in mice	5

HER2 induces cell scattering and invasion through ∆Np63α and E-cadherin	5
Mitotic bookmarking provides epigenetic persistence or plasticity for biological control and cancer	5
Effects of aldo-keto reductase family 1 member A on osteoblast differentiation associated with lactate production in MC3T3-E1 preosteoblastic cells	5
Predicting human RNA quadruplex helicases through comparative sequence approaches and helicase mRNA interactome analyses	5
The journey from bench to bedside—it takes a science village	5
Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway	4
Note of appreciation	4
Identification of critical mitochondrial hub gene for facial nerve regeneration	4
TMCO1 regulates energy metabolism and mitochondrial function of hepatocellular carcinoma cells through TOMM20, affecting the growth of subcutaneous graft tumors and infiltration of CAFs	4
Adipocyte factor CTRP6 inhibits homocysteine-induced proliferation, migration, and dedifferentiation of vascular smooth muscle cells through PPARγ/NLRP3	4
Interconnected roles of fungal nuclear- and intron-encoded maturases: at the crossroads of mitochondrial intron splicing	4
Protamines and the sperm nuclear basic proteins Pandora’s Box of insects	4
Mitogen- and stress-activated protein kinase (MSK1/2) regulated gene expression in normal and disease states	4
Gallein, G protein βγ subunits inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun N-terminal kinase	4
Pristimerin alleviates cigarette smoke-induced inflammation in chronic obstructive pulmonary disease via inhibiting NF-κB pathway	4
Evolution of techniques and tools for replication fork proteome and protein interaction studies	4
Omega-3 polyunsaturated fatty acids modify glucose metabolism in THP-1 monocytes	3
GSK126 an inhibitor of epigenetic regulator EZH2 suppresses cardiac fibrosis by regulating the EZH2-PAX6-CXCL10 pathway	3
A novel mouse model of pulmonary fibrosis: twice-repeated oropharyngeal bleomycin administration mimicking human pathology	3
Lactoferrin in the treatment of interstitial cystitis: a retrospective pilot study	3
Histone chaperone SSRP1 is required for apoptosis inhibition and mitochondrial function in HCC via transcriptional promotion of TRAP1	3
Naïve Bayes classifier assisted automated detection of cerebral microbleeds in susceptibility-weighted imaging brain images	3
Retraction: Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins	3
How prevalent are lactoferrin receptors in Gram-negative bacteria?	3
Emerging roles for heterogeneous ribonuclear proteins in normal and malignant B cells	3
Establishing validated RT-qPCR workflow for the analysis of oligodendrocyte gene expression in the developing murine brain	3
A-kinase anchoring protein 5 anchors protein kinase A to mediate PLN/SERCA to reduce cardiomyocyte apoptosis induced by hypoxia and reoxygenation	3
Aberrant mTOR/autophagy/Nurr1 signaling is critical for TSC-associated tumor development	3
Cardiovascular protective effects of GLP-1: a focus on the MAPK signaling pathway	3
Retraction: Interaction between miR-572 and PPP2R2C, and their effects on the proliferation, migration, and invasion of nasopharyngeal carcinoma (NPC) cells	3
Artesunate inhibits proliferation, migration, and invasion of thyroid cancer cells by regulating the PI3K/AKT/FKHR pathway	3
Overexpression of protein disulfide isomerase enhances vitamin K epoxide reductase activity	3
An artifact of recombinatorial cloning challenges established beliefs of plasmid cotransformation, selection, and maintenance	3
Lactoferrin efficacy in treating hyperferritinemia in patients suffering from pathologies unrelated to hereditary hemochromatosis	3
Retraction: LncRNA MALAT1 regulates diabetic cardiac fibroblasts through the Hippo–YAP signaling pathway	3
SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55	3
Early pigment spot segmentation and classification from iris cellular image analysis with explainable deep learning and multiclass support vector machine	3
LncRNAs: the good, the bad, and the unknown	3
AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer	3
Role of SIRT2 in regulating the dexamethasone-activated autophagy pathway in skeletal muscle atrophy	3
A reliable Western blot workflow with improved dynamic range for the detection of myelin proteins in murine brain	3
Chromatin remodeling factor CECR2 forms tissue-specific complexes with CCAR2 and LUZP1	3
Galanthamine promotes neuronal differentiation and neurite outgrowth of neural progenitor/stem cells by up-regulating IGF-2	3
On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions	2
Exogenous hydrogen sulfide prevents SOD2 degradation to safeguard renal function in diabetic kidney disease	2
ERCC6 plays a promoting role in the progression of non-small cell lung cancer	2
Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels	2
Purification and characterization of inorganic pyrophosphatase for in vitro RNA transcription	2
CDHR5 splice isoform cooperation promotes apical targeting of the brush border cadherin	2
Quercetin alleviates the progression of chronic rhinosinusitis by affecting nasal mucosal epithelial remodeling, inflammation, and Treg/Th17 imbalance	2
Comparative analysis of the effect of hypoxia in two different tumor cell models shows the differential involvement of PTEN control of proangiogenic pathways	2
E3 ubiquitin ligase HECW1 promotes the metastasis of non-small cell lung cancer cells through mediating the ubiquitination of Smad4	2
Automatic detection of Cryptosporidium in optical microscopy images using YOLOv5x: a comparative study	2
HSPB8 facilitates prostate cancer progression via activating the JAK/STAT3 signaling pathway	2
Targeting FHL1 impairs cell proliferation and differentiation of acute myeloid leukemia cells	2
Evaluation of drug-free methods for the detection of gene silencing in Saccharomyces cerevisiae	2
High concentrations of fructose cause brain damage in mice	2
The G protein-coupled receptor GPRC5A—a phorbol ester and retinoic acid-induced orphan receptor with roles in cancer, inflammation, and immunity	2