OOIR: Observatory of International Research

Papers

(The median citation count of Biochemistry and Cell Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
NDUFA4 promotes the progression of head and neck paraganglioma by inhibiting ferroptosis	30
RNA deadenylation complexes in development and diseases	24
Interaction between the guanylate kinase domain of PSD-95 and the proline-rich region and microtubule binding repeats 2 and 3 of tau	23
Working from within: how secretory leukocyte protease inhibitor regulates the expression of pro-inflammatory genes	19
Aberrant sphingomyelin³¹P-NMR signatures in giant cell tumour of bone	18
Retraction: MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN	16
CD142 plays a key role in the carcinogenesis of gastric adenocarcinoma by inhibiting BCL2-dependent autophagy	16
HDAC1 overexpression promoted by METTL3-IGF2BP2 inhibits FGF21 expression in metabolic syndrome-related liver injury	15
BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance	15
Cadmium chloride generates cytotoxic reactive species that cause oxidative damage and morphological changes in human erythrocytes	15
Adenylate kinases of thermophilesAquifex aeolicusandGeobacillus stearothermophilus: biochemical and kinetic studies	14
Retraction: MiR-1180 promotes cardiomyocyte cell cycle re-entry after injury through the NKIRAS2–NFκB pathway	13
Expression of concern: MicroRNA-518-3p suppresses cell proliferation, invasiveness, and migration in colorectal cancer via targeting TRIP4	13
WDR4 promotes colorectal cancer progression by activating the GSK3β/β-catenin pathway	12
Perturbation of calcium homeostasis invokes eryptosis-like cell death in enucleated bone marrow stem cells	12
ChestCovidNet: An Effective DL-based Approach for COVID-19, Lung Opacity, and Pneumonia Detection Using Chest Radiographs Images	12
Distinct domain organization and diversity of 2′-5′-oligoadenylate synthetases	11
MTHFD2 suppresses glioblastoma progression via the inhibition of ERK1/2 phosphorylation	11
Antibiofilm activities of lactoferricin-related Trp- and Arg-rich antimicrobial hexapeptides against pathogenic Staphylococcus aureus and Pseudomonas aeruginosa strains	11
GCN5 regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement	11
GCN5 enables HSP12 induction promoting chromatin remodeling, not histone acetylation	11
Bone marrow granulocytes downregulate IL-1β and TNF production and the microbicidal activity of inflammatory macrophages	10
Unveiling stem-like traits and chemoresistance mechanisms in ovarian cancer cells through the TGFβ1-PITX2A/B signaling axis	10
Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing JAK1/STAT1 pathway	10
Lipid-induced alteration in retinoic acid signaling leads to mitochondrial dysfunction in HepG2 and Huh7 cells	10

Correction: Ultrasound-stimulated microbubbles contributes to radiotherapy in esophageal carcinoma	10
Blockade of anti-dsDNA ameliorates systemic lupus erythematosus in MRL/Faslpr mice through ameliorating inflammation via the PKCδ–NLRC4 axis	10
Characterization of cells expressing lipocalin-2 (LCN2) as a reporter	9
WWP2 binds to NKRF, enhances the NF-κB signaling, and promotes malignant phenotypes of acute myeloid leukemia cells	9
Isovitexin attenuates tumor growth in human colon cancer cells through the modulation of apoptosis and epithelial-mesenchymal transition via PI3K/Akt/mTOR signaling pathway	9
Synergistic inhibitory effects of 5-aza-2′-deoxycytidine and cisplatin on urothelial carcinoma growth via suppression of TGFBI-MAPK signaling pathways	9
Antibacterial, anti-invasive, and anti-inflammatory activity of bovine lactoferrin extracted from milk or colostrum versus whole colostrum	9
Establishment of immortalized porcine intramuscular preadipocytes for the study of lipid metabolism	9
RNF38 inhibits osteosarcoma cell proliferation by binding to CRY1	9
Small proline-rich protein 1A promotes lung adenocarcinoma progression and indicates unfavorable clinical outcomes	9
Structure-based design of small molecule inhibitors of the cagT4SS ATPase Cagα of Helicobacter pylori	9
How to become a successful scientist: the 2022 CSMB Arthur Wynne Gold Medal Lecture	8
Structural features, intrinsic disorder, and modularity of a pyriform spidroin 1 core repetitive domain	8
18^th International Conference of Biochemistry & Molecular Biology (18^th ICBMB)	8
Silencing linc00662 inhibits cell proliferation and colony formation of lung cancer cells via regulating the miR-145-5p–PAFAH1B2 axis	8
Preventive cancer vaccination with P5 HER-2/neo-derived peptide‐pulsed peripheral blood mononuclear cells in a mouse model of breast cancer	8
Correction: Protective effect of nitronyl nitroxide against hypoxia-induced damage in PC12 cells	8
Neuroprotective effects of whey and buttermilk-based formulas on a DSS-induced colitis murine model	8
Substitution of histone H3 arginine 72 to alanine leads to the deregulation of isoleucine biosynthesis in the budding yeast Saccharomyces cerevisiae	8
Evaluation of biochemical profile and oxidative damage to lipids and proteins in patients with lysosomal acid lipase deficiency	7
S-allylcysteine inhibits chondrocyte inflammation to reduce human osteoarthritis via targeting RAGE, TLR4, JNK, and Nrf2 signaling: comparison with colchicine	7
Effects of clopidogrel bisulfate on B16-F10 cells and tumor development in a murine model of melanoma	7
Effects of different sources of lactoferrin on cytokine response to SARS-COV-2, respiratory syncytial virus, and rotavirus infection in vitro	7
Suppression of academics and school training in Iran during the “Woman, Life, Freedom” revolution	7
LMAN2 interacts with HEATR3 to expedite HER2-positive breast cancer advancement and inflammation and Akt/ERK/NF-κB signaling	7
Neurodevelopmental functions and activities of the KAT3 class of lysine acetyltransferases	7
RNA-binding protein NOVA1 promotes acute T-lymphocyte leukemia progression by stabilizing USP44 mRNA	7
Retraction: MiR-204 suppresses cell proliferation and promotes apoptosis in ovarian granulosa cells via targeting TPT1 in polycystic ovary syndrome	7
Recombinant human holo-lactoferrin in complex with oleic acid suppresses the growth of solid myeloma more efficiently than its apo-form	7
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease	7
Predicting human RNA quadruplex helicases through comparative sequence approaches and helicase mRNA interactome analyses	6
Structure and function of fermentation-derived bovine lactoferrin produced from Komagataella phaffii	6
Note of appreciation	6
Thidiazuron suppresses breast cancer via targeting miR-132 and dysregulation of the PI3K–Akt signaling pathway mediated by the miR-202-5p–PTEN axis	6
A role for NFIB in SOX2 downregulation and epigenome accessibility changes due to long-term estrogen treatment of breast cancer epithelial cells	6
Doxorubicin, a DNA intercalator, inhibits transcription elongation	6
Retraction: Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells	6
FYCO1 regulates migration, invasion, and invadopodia formation in HeLa cells through CDC42/N-WASP/Arp2/3 signaling pathway	6
Hoxa5 inhibits adipocyte proliferation through transcriptional regulation of Ccne1 and blocking JAK2/STAT3 signaling pathway in mice	6
The regulation of m⁶A-related proteins during whole-body freezing of the freeze-tolerant wood frog	5
Cell-in-cell-mediated intercellular communication exacerbates the pro-inflammatory progression in asthma	5
LINC00641 contributes to nasopharyngeal carcinoma cell malignancy through FOXD1 upregulation at the post-transcriptional level	5
The journey from bench to bedside—it takes a science village	5
TMCO1 regulates energy metabolism and mitochondrial function of hepatocellular carcinoma cells through TOMM20, affecting the growth of subcutaneous graft tumors and infiltration of CAFs	5
Pristimerin alleviates cigarette smoke-induced inflammation in chronic obstructive pulmonary disease via inhibiting NF-κB pathway	5
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin	5
Hydrocortisone improves post-resuscitation myocardial dysfunction by inhibiting the NF-κB pathway	5
Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway	5
Identification of critical mitochondrial hub gene for facial nerve regeneration	5
Mitogen- and stress-activated protein kinase (MSK1/2) regulated gene expression in normal and disease states	5

Retraction: Role of the TSLP–DC–OX40L pathway in asthma pathogenesis and airway inflammation in mice	5
Decreased NMIIA heavy chain phosphorylation at S1943 promotes mitoxantrone resistance by upregulating BCRP and N-cadherin expression in breast cancer cells	5
HER2 induces cell scattering and invasion through ∆Np63α and E-cadherin	5
Effects of aldo-keto reductase family 1 member A on osteoblast differentiation associated with lactate production in MC3T3-E1 preosteoblastic cells	5
Protamines and the sperm nuclear basic proteins Pandora’s Box of insects	5
Evolution of techniques and tools for replication fork proteome and protein interaction studies	5
Lactoferrin in the treatment of interstitial cystitis: a retrospective pilot study	4
Establishing validated RT-qPCR workflow for the analysis of oligodendrocyte gene expression in the developing murine brain	4
Overexpression of protein disulfide isomerase enhances vitamin K epoxide reductase activity	4
Note of appreciation	4
Gallein, G protein βγ subunits inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun N-terminal kinase	4
Retraction: Interaction between miR-572 and PPP2R2C, and their effects on the proliferation, migration, and invasion of nasopharyngeal carcinoma (NPC) cells	4
AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer	4
Artesunate inhibits proliferation, migration, and invasion of thyroid cancer cells by regulating the PI3K/AKT/FKHR pathway	4
Chromatin remodeling factor CECR2 forms tissue-specific complexes with CCAR2 and LUZP1	4
Adipocyte factor CTRP6 inhibits homocysteine-induced proliferation, migration, and dedifferentiation of vascular smooth muscle cells through PPARγ/NLRP3	4
Naïve Bayes classifier assisted automated detection of cerebral microbleeds in susceptibility-weighted imaging brain images	4
Retraction: Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins	4
LncRNAs: the good, the bad, and the unknown	4
Dlx5promotes cancer progression through regulation ofCCND1in oral squamous cell carcinoma (OSCC)	4
Interconnected roles of fungal nuclear- and intron-encoded maturases: at the crossroads of mitochondrial intron splicing	4
Histone chaperone SSRP1 is required for apoptosis inhibition and mitochondrial function in HCC via transcriptional promotion of TRAP1	4
A novel mouse model of pulmonary fibrosis: twice-repeated oropharyngeal bleomycin administration mimicking human pathology	3
Omega-3 polyunsaturated fatty acids modify glucose metabolism in THP-1 monocytes	3
Cardiovascular protective effects of GLP-1: a focus on the MAPK signaling pathway	3
Targeting FHL1 impairs cell proliferation and differentiation of acute myeloid leukemia cells	3
How prevalent are lactoferrin receptors in Gram-negative bacteria?	3
Aberrant mTOR/autophagy/Nurr1 signaling is critical for TSC-associated tumor development	3
Retraction: LncRNA MALAT1 regulates diabetic cardiac fibroblasts through the Hippo–YAP signaling pathway	3
Role of SIRT2 in regulating the dexamethasone-activated autophagy pathway in skeletal muscle atrophy	3
Comparative analysis of the effect of hypoxia in two different tumor cell models shows the differential involvement of PTEN control of proangiogenic pathways	3
Exogenous hydrogen sulfide prevents SOD2 degradation to safeguard renal function in diabetic kidney disease	3
Early pigment spot segmentation and classification from iris cellular image analysis with explainable deep learning and multiclass support vector machine	3
SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55	3
A-kinase anchoring protein 5 anchors protein kinase A to mediate PLN/SERCA to reduce cardiomyocyte apoptosis induced by hypoxia and reoxygenation	3
GSK126 an inhibitor of epigenetic regulator EZH2 suppresses cardiac fibrosis by regulating theEZH2-PAX6-CXCL10pathway	3
Lactoferrin efficacy in treating hyperferritinemia in patients suffering from pathologies unrelated to hereditary hemochromatosis	3
HSPB8 facilitates prostate cancer progression via activating the JAK/STAT3 signaling pathway	3
Emerging roles for heterogeneous ribonuclear proteins in normal and malignant B cells	3
Knockdown of SGLT1 prevents the apoptosis of cardiomyocytes induced by glucose fluctuation via relieving oxidative stress and mitochondrial dysfunction	3
ERCC6 plays a promoting role in the progression of non-small cell lung cancer	2
Evaluation of drug-free methods for the detection of gene silencing in Saccharomyces cerevisiae	2
High concentrations of fructose cause brain damage in mice	2
Single-cell genomics illustrates heterogeneous phenotypes of myocardial fibroblasts under ischemic insults	2
The biological relevance of PCSK9: when less is better…	2
Angptl2 gene knockdown is critical for abolishing angiotensin II-induced vascular smooth muscle cell proliferation and migration	2
On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions	2
E3 ubiquitin ligase HECW1 promotes the metastasis of non-small cell lung cancer cells through mediating the ubiquitination of Smad4	2
The G protein-coupled receptor GPRC5A—a phorbol ester and retinoic acid-induced orphan receptor with roles in cancer, inflammation, and immunity	2
The AC006262.5–miR-7855-5p–BPY2C axis facilitates hepatocellular carcinoma proliferation and migration	2
The endless battle between phages and CRISPR–Cas systems in Streptococcus thermophilus	2
Retraction: Prognostic value and oncogenic effect of increased RBM8A expression in colon adenocarcinoma	2
Automatic detection of Cryptosporidium in optical microscopy images using YOLOv5x: a comparative study	2
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1	2
Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels	2
1-Deoxynojirimycin affects high glucose-induced pancreatic beta-cell dysfunction through regulating CEBPA expression and AMPK pathway	2
Purification and characterization of inorganic pyrophosphatase for in vitro RNA transcription	2