Annals of Medicine

Article	Citations
EQ-SD: a measure of health status from the EuroQol Group	3402
The Caveolin genes: from cell biology to medicine	287
Polyamines: from Molecular Biology to Clinical Applications	256
New population-based references for birth weight, length, and head circumference in singletons and twins from 23 to 43 gestation weeks	165
Long-term consequences of maternal overweight in pregnancy on offspring later health: Findings from the Helsinki Birth Cohort Study	147
Genetic contributions to preterm birth: Implications from epidemiological and genetic association studies	110
Different genes, different diabetes: lessons from maturity-onset diabetes of the young	97
Does childhood nutrition influence adult cardiovascular disease risk?—Insights from the Young Finns Study	96
Corticotropin‐releasing hormone (CRH) in psychiatry: from stress to psychopathology	88
Cannabinoids and the skeleton: From marijuana to reversal of bone loss	74
Admission hyperglycaemia as a predictor of mortality in patients hospitalized with COVID-19 regardless of diabetes status: data from the Spanish SEMI-COVID-19 Registry	72
Developmental Origins of Health and Disease – from a small body size at birth to epigenetics	72
Clinical and inflammatory features based machine learning model for fatal risk prediction of hospitalized COVID-19 patients: results from a retrospective cohort study	71
The threat from the pink corner	69
Ventricular interaction: from bench to bedside	63
Genetic and Environmental Factors in Sciatica Evidence from a Nationwide Panel of 9365 Adult Twin Pairs	62
Maternal weight in pregnancy and offspring body composition in late adulthood: Findings from the Helsinki Birth Cohort Study (HBCS)	54
Serum uric acid change and modification of blood pressure and fasting plasma glucose in an overall healthy population sample: data from the Brisighella heart study	46
Changes in estimated coronary risk in the 1980s: data from 38 populations in the WHO MONICA Project	45
Unravelling the health effects of fasting: a long road from obesity treatment to healthy life span increase and improved cognition	44
Hereditary and acquired C1-inhibitor-dependent angioedema: from pathophysiology to treatment	44
Hydroxychloroquine: a comprehensive review and its controversial role in coronavirus disease 2019	43
Aetiological diagnosis of infective endocarditis by direct amplification of rRNA genes from surgically removed valve tissue. An 11‐year experience in a Finnish teaching hospital	42
Fetal RhD genotyping from maternal plasma	42
Joint analysis of individual participants’ data from 17 studies on the association of theIL6variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index	42

Dietary interventions in fibromyalgia: a systematic review	41
A multidisciplinary consensus on dehydration: definitions, diagnostic methods and clinical implications	40
Increased expression of hypoxia-induced factor 1α mRNA and its related genes in myeloid blood cells from critically ill COVID-19 patients	37
Heart rate as a cardiovascular risk factor: do women differ from men?	37
Triglyceride-rich Lipoproteins and Atherosclerosis, from Fast to Feast	36
Is monocyte to HDL ratio superior to monocyte count in predicting the cardiovascular outcomes: evidence from a large cohort of Chinese patients undergoing coronary angiography	36
Age-related risk of mortality from bladder cancer in diabetic patients: A 12-year follow-up of a national cohort in Taiwan	35
Extensive phenotype data and machine learning in prediction of mortality in acute coronary syndrome – the MADDEC study	35
Effect of alpha-tocopherol and beta-carotene supplementation on macrovascular complications and total mortality from diabetes: Results of the ATBC Study	35
Impaired albumin function: a novel potential indicator for liver function damage?	33
Trends in treatment and outcome of stroke patients in Finland from 1999 to 2007. PERFECT Stroke, a nationwide register study	32
Estimation of VLDL, IDL, LDL, HDL2, apoA-I, and apoB from the Friedewald inputs—apoB and IDL, but not LDL, are associated with mortality in type 1 diabetes	31
Lipoprotein predictors of cardiovascular events in statin-treated patients with coronary heart disease. Insights from the Incremental Decrease in End-points through Aggressive Lipid-lowering Trial (ID	31
Impact of Xuezhikang on coronary events in hypertensive patients with previous myocardial infarction from the China Coronary Secondary Prevention Study (CCSPS)	31
Molecular assessment of depression from mRNAs in the peripheral leukocytes	30
Disparities in case frequency and mortality of coronavirus disease 2019 (COVID-19) among various states in the United States	29
Microparticles and cardiovascular diseases	28
Low levels of vitamin D are associated with multimorbidity: Results from the LifeLines Cohort Study	28
A missense mutation in CASQ2 is associated with autosomal recessive catecholamine‐induced polymorphic ventricular tachycardia in Bedouin families from Israel	28
Cardiovascular Risk in Young Finns, Results from the Second Follow-Up Study	27
Early life body mass trajectories and mortality in older age: Findings from the Helsinki Birth Cohort Study	27
Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: Results from the PPP-Botnia Study	27
Prognostic significance of CDKN2A/B deletions in acute lymphoblastic leukaemia: a meta-analysis	26
Cardiomyocytes derived from stem cells	26
The role of exosome in autoimmune connective tissue disease	25
Adult vaccination as part of a healthy lifestyle: moving from medical intervention to health promotion	23
Discrete roles of apoA‐I and apoE in the biogenesis of HDL species: Lessons learned from gene transfer studies in different mouse models	23
Cardiac channelopathies: from men to mice	23
Center-based patient care enhances survival of elderly patients suffering from peripheral arterial disease	22
How to Apply the Experience from the Diabetes Control and Complications Trial to Children and Adolescents?	22
Effect of a genetically engineered interferon-alpha versus traditional interferon-alpha in the treatment of moderate-to-severe COVID-19: a randomised clinical trial	21
Developmental paradigms in heart disease: insights from tinman	21
Evidence-based nutrition: Does it differ from evidence-based medicine?	21
Girls Adopted from Developing Countries: a Group at Risk of Early Pubertal Development and Short Final Height. Implications for Health Surveillance and Treatment	21
Lipoprotein(a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options	21
Regional Differences in the Incidence of Insulin-dependent Diabetes Mellitus among Children in Finland from 1987 to 1991	21
Chronic diseases and objectively monitored physical activity profile among aged individuals – a cross-sectional twin cohort study	21
White matter hyperintensities – from medical comorbidities to bipolar disorders and back	21
Glycaemic efficacy and safety of linagliptin for the management of non-cardiac surgery patients with type 2 diabetes in a real-world setting: Lina-Surg study	20
Cardiovascular health in urban Chinese children and adolescents	20
Collective intelligence for translational medicine: Crowdsourcing insights and innovation from an interdisciplinary biomedical research community	20
A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: Results from two randomized	19
HDL therapy today: from atherosclerosis, to stent compatibility to heart failure	19
Treatment ofClostridioides (Clostridium) difficileinfection	19
Enhancing the ‘real world’ prediction of cardiovascular events and major bleeding with the CHA2DS2-VASc and HAS-BLED scores using multiple biomarkers	19
The Circadian Clock: From Molecules to Behaviour	19
Exercise intolerance resulting: from a muscle-restricted mutation in the mitochondrial tRNALeu(CUN)gene	18
The elevated CXCL5 levels in circulation are associated with lung function decline in COPD patients and cigarette smoking-induced mouse model of COPD	17
A risk–benefit assessment strategy to exclude cervical artery dissection in spinal manual-therapy: a comprehensive review	17
Epigenetic reprogramming in breast cancer: From new targets to new therapies	17

Insulin resistance takes center stage: a new paradigm in the progression of bipolar disorder	17
Where Is the Lumbar Pain Coming from?	17
New Finnish reference for head circumference from birth to 7 years	16
Hereditary tyrosinaemia type I: from basics to progress in treatment	16
Pre-pandemic mental and physical health as predictors of COVID-19 vaccine hesitancy: evidence from a UK-wide cohort study	16
Human Circadian Rhythms: Lessons from the Blind	16
Is Mastocytosis a Mast Cell Neoplasia or a Reactive Hyperplasia? Clues from the Study of Mast Cell Growth Factor	15
Nighttime sleep duration and risk of nonalcoholic fatty liver disease: the Dongfeng-Tongji prospective study	15
Health state values from multiattribute utility instruments need correction	15
Treatment response to sleep, pain, and mood disturbance and their correlation with sleep disturbance in adult patients with moderate-to-severe primary restless legs syndrome: Pooled analyses from 3 tr	15
Stent-oriented versus patient-oriented outcome in patients undergoing early percutaneous coronary intervention for acute coronary syndrome: 2-year report from the BASE-ACS trial	14
How to Define Coronary Heart Disease in Register-based Follow-up Studies: Experience from the Helsinki Heart Study	14
Associations between sleep disturbances and diabetes mellitus among blacks with metabolic syndrome: Results from the Metabolic Syndrome Outcome Study (MetSO)	14
From holoprosencephaly to osteopathology: role of multifunctional endocytic receptors in absorptive epithelia	14
Comparison of risk profiles between survivors and victims of sudden cardiac death from an acute coronary event	14
New treatment options for substance abuse from a public health viewpoint	14
Sex, age, and time to cardioversion. Risk factors for cardioversion of acute atrial fibrillation from the FinCV study	13
Lessons from Twin Studies in Finland	13
Impact of multimorbidity and polypharmacy on the management of patients with atrial fibrillation: insights from the BALKAN-AF survey	13
Efficacy and safety of fecal microbiota transplantation for decolonization of intestinal multidrug-resistant microorganism carriage: beyond Clostridioides difficile infection	13
Genetics in the Prediction of Insulin-dependent Diabetes Mellitus: From Theory to Practice	13
High-density lipoprotein: A fall from grace?	12
Ten-year experience with transcatheter and surgical aortic valve replacement in Finland	12
Prognostic implications of quantitative ST-segment characteristics and T-wave amplitude for cardiovascular mortality in a general population from the Health 2000 Survey	12
Carcinomatosis from gastrointestinal cancer	12
Hypertension is a risk factor for adverse outcomes in patients with coronavirus disease 2019: a cohort study	11
A new prediction model for assessing the clinical outcomes of ICU patients with community-acquired pneumonia: a decision tree analysis	11
Titanium-nitride-oxide-coated coronary stents: insights from the available evidence	11
Combination of low blood pressure response, low exercise capacity and slow heart rate recovery during an exercise test significantly increases mortality risk	11
Inflammatory bowel disease: new therapies from antisense oligonucleotides	11
Use of antihypertensive medication after ischemic stroke in young adults and its association with long-term outcome	10
The effect of comorbid medical and psychiatric diagnoses on chronic fatigue syndrome	10
Cardiovascular fitness in young males and risk of unprovoked venous thromboembolism in adulthood	9
Identification of novel variants in ten patients with Hermansky-Pudlak syndrome by high-throughput sequencing	9
Bioinformatics: from genome to drug targets	9
Global, regional and national burden of gastroesophageal reflux disease, 1990–2019: update from the GBD 2019 study	9
Left atrial thrombus resolution in non-valvular atrial fibrillation or flutter: biomarker substudy results from a prospective study with rivaroxaban (X-TRA)	9
Efficacy and safety of intravenous esmolol for cardiac protection in non-cardiac surgery. A systematic review and meta-analysis	9
Extending medical interfaces towards virtual reality and augmented reality	9
Pleural effusion volume in patients with acute pancreatitis: a retrospective study from three acute pancreatitis centers	9
Systemic effects of controlled exposure to diesel exhaust: a meta-analysis from randomized controlled trials	9
Haplotype analysis and identification of genes for a complex trait: examples from schizophrenia	9
Predictors of high hospital care and medication costs and cost trajectories in community-dwellers with Alzheimer’s disease	9
Plasma Klotho concentrations predict functional outcome at three months after acute ischemic stroke patients	8
Clinical and prognostic characteristics of 95 cases of Langerhans cell histiocytosis in children: a single-institute experience from 2013 to 2020	8
Tracking of Serum Lipoprotein (a) Concentration and Its Contribution to Serum Cholesterol Values in Children from 7 to 36 Months of Age in the STRIP Baby Study	8
Electrical remodeling and arrhythmias in long‐QT syndrome: lessons from genetic models in mice	8
Thoracic endovascular aortic repair versus open chest surgical repair for patients with type B aortic dissection: a systematic review and meta-analysis	8
Low-dose aspirin and risk of upper/lower gastrointestinal bleeding by bleed severity: a cohort study with nested case-control analysis using primary care electronic health records from the United King	8
Evidence for daily and weekly rhythmicity but not lunar or seasonal rhythmicity of physical activity in a large cohort of individuals from five different countries	8
Low anthropometric measures and mortality—results from the Malmö Diet and Cancer Study	8
Experience from Clinical Trials in Cancer Prevention	8
Coeliac disease: beyond genetic susceptibility and gluten. A narrative review	8
Evaluating red blood cell distribution width from community blood tests as a predictor of hospitalization and mortality in adults with SARS-CoV-2: a cohort study	8
From gene transfer to gene therapy in lysosomal storage diseases affecting the central nervous system	8