Fundamental & Clinical Pharmacology

Papers
(The TQCC of Fundamental & Clinical Pharmacology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Chemsex practice in France: An update in Addictovigilance data30
Oral drug delivery with nanoparticles into the gastrointestinal mucosa30
Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments30
Hepatoprotective and therapeutic effects of resveratrol: A focus on anti‐inflammatory and antioxidative activities30
Antiviral therapies: advances and perspectives29
Poster Abstracts28
Poster Abstracts28
A systematic review of experimental evidence for antiviral effects of ivermectin and an in silico analysis of ivermectin's possible mode of action against SARS‐CoV‐227
Progress on ocular siRNA gene‐silencing therapy and drug delivery systems25
Melatonin and morphine: potential beneficial effects of co‐use25
Sildenafil beyond erectile dysfunction and pulmonary arterial hypertension: Thinking about new indications25
In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease24
Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities23
Omentin‐1 attenuates adipose tissue inflammation via restoration of TXNIP/NLRP3 signaling in high‐fat diet‐induced obese mice22
Neuropharmacology in traumatic brain injury: from preclinical to clinical neuroprotection?22
Genesis of an emergency public drug information website by the French Society of Pharmacology and Therapeutics during the COVID‐19 pandemic21
Differential effects of alliin and allicin on apoptosis and senescence in luminal A and triple‐negative breast cancer: Caspase, ΔΨm, and pro‐apoptotic gene involvement21
Targeting Wnt/β‐catenin by anthelmintic drug niclosamide overcomes paclitaxel resistance in esophageal cancer19
Novel potential of metformin on valproic acid‐induced autism spectrum disorder in rats: involvement of antioxidant defence system18
Valproic acid reverses sorafenib resistance through inhibiting activated Notch/Akt signaling pathway in hepatocellular carcinoma18
Sumatriptan reduces severity of status epilepticus induced by lithium–pilocarpine through nitrergic transmission and 5‐HT1B/D receptors in rats: A pharmacological‐based evidence18
The clinical meaning of levodopa equivalent daily dose in Parkinson's disease17
Anti‐inflammatory effect of amitriptyline in a rat model of acetic acid‐induced colitis: the involvement of the TLR4/NF‐kB signaling pathway17
Ceftriaxone‐associated biliary pseudolithiasis in children: do we know enough?17
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice17
Poster Abstracts17
Protective effect of fenofibrate against high‐fat–high‐fructose diet induced non‐obese NAFLD in rats16
Psychoactive substance use among students: A cross‐sectional analysis16
The possible role of CREB‐BDNF signaling pathway in neuroprotective effects of minocycline against alcohol‐induced neurodegeneration: molecular and behavioral evidences16
Exploring the beneficial role of ROCK inhibitors in sepsis‐induced cerebral and cognitive injury in rats16
Mineralocorticoid receptor antagonist‐mediated cognitive improvement in a mouse model of Alzheimer's type: possible involvement of BDNF‐H2S‐Nrf2 signaling16
Remdesivir potently inhibits carboxylesterase‐2 through covalent modifications: signifying strong drug‐drug interactions15
Drug‐induced vitiligo: a case/non‐case study in Vigibase®, the WHO pharmacovigilance database15
Comparison of the effects of losartan, captopril, angiotensin II type 2 receptor agonist compound 21, and MAS receptor agonist AVE 0991 on myocardial ischemia–reperfusion necrosis in rats14
Health consequences of cocaine use in France: data from the French Addictovigilance Network14
Outcome of patients hospitalized for COVID‐19 and exposure to angiotensin‐converting enzyme inhibitors and angiotensin‐receptor blockers in France: results of the ACE‐CoV study14
Is lithium neuroprotective? An updated mechanistic illustrated review13
Evaluation of the neuroprotective effect of donepezil in type 2 diabetic rats12
Targeting IL‐10, ZO‐1 gene expression and IL‐6/STAT‐3 trans‐signaling by a combination of atorvastatin and mesalazine to enhance anti‐inflammatory effects and attenuates progression of oxazolone‐induc12
Cannabidiol alleviates hemorrhagic shock‐induced neural apoptosis in rats by inducing autophagy through activation of the PI3K/AKT pathway12
Pharmacological agents under investigation in the treatment of coronavirus disease 2019 and the importance of melatonin11
Development of pyrazole derivatives in the management of inflammation11
Is the mechanism of action of antiseizure drugs a key element in the choice of treatment?11
Fentanyl inhibits acute myeloid leukemia differentiated cells and committed progenitors via opioid receptor‐independent suppression of Ras and STAT5 pathways10
Impact of bariatric surgery on oral anticoagulants pharmacology, and consequences for clinical practice: a narrative review10
Angiotensin aldosterone inhibitors improve survival and ameliorate kidney injury induced by sepsis through suppression of inflammation and apoptosis10
Ivabradine improves survival and attenuates cardiac remodeling in isoproterenol‐induced myocardial injury10
The contributions of metabolomics in the discovery of new therapeutic targets in Alzheimer's disease10
Melatonin has an inhibitory effect on MCF‐7 and MDA‐MB‐231 human breast cancer cell lines by inducing autophagy and apoptosis10
Rapamycin attenuates depression and anxiety‐like behaviors through modulation of the NLRP3 pathway in pentylenetetrazole‐kindled male Wistar rats10
Drug adulteration of sexual enhancement supplements: a worldwide insidious public health threat10
N‐(benzylidene)‐2‐((2‐hydroxynaphthalen‐1‐yl)diazenyl)benzohydrazides (1‐2) (NCHDH and NTHDH) attenuate DMBA‐induced breast cancer via Nrf2/NF‐κB/apoptosis signaling10
Bupivacaine inhibits angiogenesis through oxidative stress‐dependent inhibition of Akt/mTOR and activation of AMPK9
Safety concerns on the abuse potential of esketamine: Multidimensional analysis of a new anti‐depressive drug on the market9
An overview of ongoing clinical trials assessing pharmacological therapeutic strategies to manage chemotherapy‐induced peripheral neuropathy, based on preclinical studies in rodent models9
Overview of French databases available for studying anticancer drugs in real‐life setting9
Lacosamide improves biochemical, genotoxic, and mitochondrial parameters after PTZ‐kindling model in mice9
Bisoprolol, a β1 antagonist, protects myocardial cells from ischemia–reperfusion injury via PI3K/AKT/GSK3β pathway9
Antidepressants with anti‐tumor potential in treating glioblastoma: A narrative review9
Dexamethasone and p38 MAPK inhibition of cytokine production from human lung fibroblasts9
Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors9
Doctor shopping for methylphenidate as a proxy for misuse and potential abuse in the 67 million inhabitants in France9
Abemaciclib sensitizes HPV‐negative cervical cancer to chemotherapy via specifically suppressing CDK4/6‐Rb‐E2F and mTOR pathways9
Plasma gonadotropin levels in metformin‐treated men with prediabetes: a non‐randomized, uncontrolled pilot study9
Impact of interleukin‐6 on drug transporters and permeability in the hCMEC/D3 blood–brain barrier model8
Improvement of cognitive function, glucose and lipid homeostasis and serum osteocalcin levels by liraglutide in diabetic rats8
COVID‐19 in DMARD‐treated patients with inflammatory rheumatic diseases: Insights from an analysis of the World Health Organization pharmacovigilance database8
Gemfibrozil, a lipid‐lowering drug, reduces anxiety, enhances memory, and improves brain oxidative stress in d‐galactose‐induced aging mice8
NVX‐Cov2373 Novavax Covid‐19 vaccine: A further analysis of its efficacy using multiple modes of expression7
Tyrosine kinase inhibitors and direct oral anticoagulants: In vitro evaluation of drug–drug interaction mediated by P‐glycoprotein7
Study of prescription‐indication of tetracyclines in a population in Colombia7
The HIV reverse transcriptase Inhibitor Tenofovir suppressed DMH/HFD‐induced colorectal cancer in Wistar rats7
Medication non‐adherence after allogeneic hematopoietic cell transplantation in adult and pediatric recipients: a cross sectional study conducted by the Francophone Society of Bone Marrow Transplantat7
Safety profile of hydroxychloroquine used off‐label for the treatment of patients with COVID‐19: A descriptive study based on EudraVigilance data7
Are potentially inappropriate and anticholinergic medications being prescribed for institutionalized elderly subjects?7
Anisomycin sensitizes non‐small‐cell lung cancer cells to chemotherapeutic agents and epidermal growth factor receptor inhibitor via suppressing PI3K/Akt/mTOR7
Advances on pharmacology and toxicology of aconitine7
Effect of dapagliflozin and/or L‐arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor‐beta 1, autophagy, and apoptosis6
Effects of physical activity on cell‐to‐cell communication during type 2 diabetes: A focus on miRNA signaling6
Antihyperlipidemic effect of selected pyrimidine derivatives mediated through multiple pathways6
Can chronopharmacology improve the therapeutic management of neurological diseases?6
Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases6
Cluster headache: state of the art of pharmacological treatments and therapeutic perspectives6
KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury6
The PI3Kγ/AKT signaling pathway mediates peripheral antinociceptive action of dipyrone6
Xanthotoxin enhances the anticonvulsant potency of levetiracetam and valproate in the 6‐Hz corneal stimulation model in mice6
Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments6
Evaluating and modulating TFEB in the control of autophagy: toward new treatments in CNS disorders6
Targeting cannabinoid receptor 2 (CB2) limits collagen production—An in vitro study in a primary culture of human fibroblasts6
Orexin receptors: Targets and applications6
Vortioxetine as an analgesic in preclinical inflammatory pain models: Mechanism of action6
Ameliorative effect of ozagrel, a thromboxane A2 synthase inhibitor, in hyperhomocysteinemia‐induced experimental vascular cognitive impairment and dementia6
Function of intestinal barrier protected by regulating the miR‐199a‐3p in ulcerative colitis: Modulation of IL‐23/IL‐17A axis6
Vasorelaxant effect of trans‐4‐chloro‐β‐nitrostyrene, a synthetic nitroderivative, in rat thoracic aorta6
Inhibition MNK‐eIF4E‐β‐catenin preferentially sensitizes gastric cancer to chemotherapy6
Antibiotics with therapeutic effects on spinal cord injury: a review6
Effect of sacubitril/valsartan on cognitive impairment in colchicine‐induced Alzheimer's model in rats6
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma5
Tramadol‐induced hypoglycemia: A pharmacovigilance study5
Spermidine reduced neuropathic pain in chronic constriction injury‐induced peripheral neuropathy in rats5
Adverse effects of gender‐affirming hormonal therapy in transgender persons: Assessing reports in the French pharmacovigilance database5
Lacosamide‐induced personality changes: An unexpected adverse effect5
Na+, K+‐ATPase participates in the protective mechanism of rat cerebral ischemia‐reperfusion through the interaction with glutamate transporter‐15
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats5
Ferulic acid mitigates diabetic cardiomyopathy via modulation of metabolic abnormalities in cardiac tissues of diabetic rats5
Simvastatin–Ezetimibe enhances growth factor expression and attenuates neuron loss in the hippocampus in a model of intracerebral hemorrhage5
Short‐chain fatty acids increase intracellular calcium levels and enhance gut hormone release from STC‐1 cells via transient receptor potential Ankyrin15
Absence of ethnic difference on single‐dose pharmacokinetics of rivoceranib between healthy male Caucasian, Japanese, and Chinese subjects5
The cyclin‐dependent kinase inhibitor AT7519 augments cisplatin's efficacy in ovarian cancer via multiple oncogenic signaling pathways5
Impact of anesthetics on oncogenic signaling network: a review on propofol and isoflurane5
Variability of rituximab and tocilizumab trough concentrations in patients with rheumatoid arthritis5
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model5
Efficacy of COVID‐19 vaccines: Several modes of expression should be presented in scientific publications5
Viral target and metabolism‐based rationale for combined use of recently authorized small molecule COVID‐19 medicines: Molnupiravir, nirmatrelvir, and remdesivir5
Sitagliptin's renoprotective effect in a diabetic nephropathy model in rats: The potential role of PI3K/AKT pathway4
Chronic polypharmacy at all age: A population‐based drug utilization study4
Mechanisms underlying the vasorelaxant effect of hydrogen sulfide on human saphenous vein4
Activation of the Mas receptors by AVE0991 and MrgD receptor using alamandine to limit the deleterious effects of Ang II‐induced hypertension4
Chemsex in HIV pre‐exposure prophylaxis users: Assessment of mood disorders and addictive behavior4
Animal models for the evaluation of antipsychotic agents4
Patch testing versus interferon‐gamma release assay in evaluation of drug eruptions4
Ten‐year trends in hospitalizations related to cocaine abuse in France4
Edaravone inhibits procaspase‐3 denitrosylation and activation through FasL‐Trx2 pathway in KA‐induced seizure4
Trends in the use of antihistamines with reference to drivers between 2015 and 2019: A population‐based registry analysis4
An insight into the pharmacological and analytical potential of Andrographolide4
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging4
Tofacitinib improved peripheral endothelial dysfunction and brain‐derived neurotrophic factor levels in the rat adjuvant‐induced arthritis model4
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?4
Atorvastatin disrupts primary human brain microvascular endothelial cell functions via prenylation‐dependent mitochondrial inhibition and oxidative stress4
Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro4
Increased risk of urinary tract infection and pyelonephritis under concomitant use of sodium‐dependent glucose cotransporter 2 inhibitors with antidiabetic, antidyslipidemic, and antihypertensive drug4
Inhibition of eukaryotic initiation factor 4E by tomivosertib suppresses angiogenesis, growth, and survival of glioblastoma and enhances chemotherapy's efficacy4
Liver‐Expressed Antimicrobial Peptide 2 antagonizes the insulinostatic effect of ghrelin in rat isolated pancreatic islets4
Sakuranetin exerts anticonvulsant effect in bicuculline‐induced seizures4
Pentosan polysulfate exerts anti‐inflammatory effect and halts albuminuria progression in diabetic nephropathy: Role of combined losartan4
Is the human model RPTEC/TERT1 a relevant model for assessing renal drug efflux?4
Quantification of serum levels in mice of seven drugs (and six metabolites) commonly taken by older people with polypharmacy4
Antioxidant activities of artesunate–procyanidin hybrid compound in erythrocyte and liver of Plasmodium berghei NK65‐infected mice4
What changes in prescription patterns of antiemetic medications in pregnant women in France?4
Immunomodulatory effect of N‐acetyl‐seryl‐aspartyl‐proline and vasoactive intestinal peptide on chronic obstructive pulmonary disease pathophysiology4
Effect of food on the single‐dose pharmacokinetics and tolerability of savolitinib in Chinese healthy volunteers4
A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms4
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