OOIR: Observatory of International Research

Papers

(The TQCC of Fundamental & Clinical Pharmacology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin	60
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?	58
In vitro evidence that the vasorelaxant effects of 2‐nitro‐1‐phenyl‐1‐propanol on rat coronary arteries involve cyclic nucleotide pathways	56
	50
Protective Effects of Cannabis sativa on chemotherapy‐induced nausea in a rat: Involvement of CB1 receptors	31
Can cannabidiol have an analgesic effect?	30
Novel ginsenoside monomer RT4 promotes colitis repair in mice by regulating miR‐144‐3p/SLC7A11 signaling pathway	27
Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats	24
Methylsulfonylmethane induces caspase‐dependent apoptosis in acute myeloid leukemia cell lines	22
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil	22
Effects of FECH Gene Polymorphisms and Serum Ferrochelatase Levels on Antituberculosis Drug‐Induced Liver Injury in China	19
Effect of ceftriaxone on intestinal transit time	18
Inhibition of NorA efflux pump of Staphylococcus aureus by anacardic acids isolated from the cashew nutshell liquid of Anacardium occidentale L.	18
	17
Tofacitinib improved peripheral endothelial dysfunction and brain‐derived neurotrophic factor levels in the rat adjuvant‐induced arthritis model	17
Calcium dobesilate protects against d‐galactose‐induced hepatic and renal dysfunction, oxidative stress, and pathological damage	17
MiR‐199a‐3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury	17
Relative bioavailability and pharmacokinetic comparison of a fixed‐dose combination tablet of mosapride, pancreatin, and simethicone relative to single‐component mosapride tablets in healthy Mexican s	17
Precipitation of sugammadex with nicardipine and labetalol: A laboratory research	15
Sakuranetin exerts anticonvulsant effect in bicuculline‐induced seizures	15
Evaluation of anti‐inflammatory activity of kaurenol: Experimental evaluation and mechanistic insights	14
Metformin improves neurobehavioral impairments of streptozotocin‐treated and western diet‐fed mice: Beyond glucose‐lowering effects	14
Master 2 Award	14
Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer	14
Issue Information	14

Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging	14
Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy	13
Treatment implications of augmented renal clearance in a critically ill COVID‐19 patient: A case report	12
Cover Image, Volume 36, Issue 1	12
Cell therapy procedure using anti‐inflammatory macrophage M2 can potentially reduce Clinical Score in animals with Experimental Autoimmune Encephalomyelitis: A preclinical systematic review and meta‐a	12
Spontaneous reporting of adverse drug reactions as an outlet for patient dismay? The case of Levothyrox® change of excipients	11
Issue Information	11
Histamine H1‐ and H2‐receptors participate to provide metabolic energy differently	11
Issue Information	11
Vestibular disorders following BNT162b2 mRNA COVID‐19 vaccination: A retrospective case series	10
Thesis awards	10
UPLC‐MS analysis and network pharmacology‐based investigation into the active ingredients and molecular mechanisms of anti‐fatigue of male flowers with Eucommia ulmoides Oliv.	10
Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study)	10
Chlorogenic acid co‐administration alleviates cisplatin‐induced peripheral neuropathy in rats	10
Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities	10
Acetazolamide suppresses the progression of hepatocellular carcinoma induced by diethylnitrosamine in Wistar albino rats	10
Sitagliptin's renoprotective effect in a diabetic nephropathy model in rats: The potential role of PI3K/AKT pathway	10
Master 2 award	10
A novel naphthylchalcone ([E]‐4‐(3‐[naphthalen‐2‐yl]‐3‐oxoprop‐1‐en‐1‐yl) induces intrinsic and extrinsic apoptosis in human acute leukemia cell lines	9
A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms	9
	9
Capivasertib augments chemotherapy via Akt inhibition in preclinical small cell lung cancer models	9
Chemsex practice in France: An update in Addictovigilance data	9
Issue Information	9
Issue Information	9
Theme and main topic index	9
Therapeutic targeting of DNA damage repair pathways guided by homologous recombination deficiency scoring in ovarian cancers	8
	8
Bupivacaine inhibits the TLR4‐ and TLR2‐Myd88/NF‐κB pathways in human leukocytes	8
	8
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats	8
Use of real‐world evidence in translational pharmacology research	8
	8
Inhibition of kidney potassium channels by fluoxetine: In vivo and in vitro studies	8
Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis	8
Inhibition of plasminogen suppresses fibrosis and macrophage foaming in a nonalcoholic steatohepatitis mouse model	8
Vitamin D lacks efficacy: A re‐analysis of a systematic review using the REB method	8
Necrostatin‐1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice	8
Anti‐oxidative and anti‐neuroinflammatory role of Necrostatin‐1s and docosahexaenoic acid in RIP‐1‐mediated neurotoxicity in MPTP‐induced Parkinson's disease model	8
Effects of nalbuphine on the cardiotoxicity of ropivacaine in rats	8
Differential expression and activities of cytochrome P450 3A in the rat brain microsomes and mitochondria	8
	7
Issue Information	7
Vitamin D3 potentiates the nephroprotective effects of vildagliptin–metformin combination in a rat model of metabolic syndrome	7
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case	7
Adrenaline enhances nociceptive and motor blockades by intrathecal carteolol and oxprenolol in rats	7
Advances in the phytochemical screening and biological potential of propolis	7
Animal models for the evaluation of antipsychotic agents	7
Deliberation on debilitating condition of cancer cachexia: Skeletal muscle wasting	7
Antihypertensive and lipid‐lowering drugs usage after primary stroke in a large representative sample of the French population	7

Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases	7
Oral communication abstracts	7
Discussed Poster Abstracts – PM2	7
Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency	7
Involvement of different K⁺ channel subtypes in hydrogen sulfide‐induced vasorelaxation of human internal mammary artery	7
Effect of a high‐fat meal on the relative bioavailability of HMPL‐689 in Chinese healthy volunteers	7
Issue Information	6
	6
Tamsulosin Attenuates Cardiac Hypertrophy via Integrin‐Linked Kinase: Possible Mechanisms	6
The effects of cannabidiol on subjective states, cognition, and psychomotor function in healthy adults: A randomized clinical trial	6
Discussed Poster Abstracts – PM1	6
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model	6
Probing polypharmacy, ageing and sex effects on physical function using different tests	6
Chronic polypharmacy at all age: A population‐based drug utilization study	6
Master 2 award	6
	6
Lacosamide use during breastfeeding: A case report and a literature review	6
Prevalence of medication administration errors in hospitalized adults: A systematic review and meta‐analysis up to 2017 to explore sources of heterogeneity	6
Recognition of potential therapeutic role of 2‐hydroxy‐3‐methylanthraquinones in the treatment of gallbladder carcinoma: A proteomics analysis	6
Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains	6
Oral Communication Abstracts	6
Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats	6
Atorvastatin ameliorates α‐KGDH and GDH functions in rats with diet‐induced hypercholesterolemia	6
Drug news and therapeutic news	6
Update on monkeypox virus infection: Focusing current treatment and prevention approaches	6
Drug‐induced radiation recall reactions and non‐anticancer drugs: A descriptive analysis from VigiBase®	6
Analgesic switching in chronic users of dextropropoxyphene in France	6
Relapse and New‐Onset of Autoimmune or Inflammatory Diseases Following Vaccination With SPIKEVAX: Pharmacovigilance Overview From the French Spontaneous Reported System	5
Drug news and therapeutic news	5
Afatinib triggers a Ni²⁺‐resistant Ca²⁺ influx pathway in A549 non‐small cell lung cancer cells	5
A mini‐review on anticancer‐related properties of azithromycin and its potential activities in overcoming the challenges of glioblastoma	5
Development of a Bayesian estimation tool to determine the optimal duration of apixaban discontinuation before a high‐bleeding risk procedure	5
Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes	5
Inflammatory molecules facilitate the development of docetaxel‐resistant prostate cancer cells in vitro and in vivo	5
LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice	5
Insights into nanostructured lipid carriers of etoricoxib for mitigating radiation‐induced lung inflammation and exploring anti‐inflammatory mechanisms in rats	5
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma	5
In vitro evidence that the anti‐inflammatory effect of synthetic cinnamate‐derived dienes is directly linked to a macrophage repolarization	5
Population pharmacokinetics of sivelestat in Chinese patients with severe pneumonia	5
JAK/STAT inhibitors mitigate sepsis‐associated cerebral and cognitive injury	5
Is lithium neuroprotective? An updated mechanistic illustrated review	5
Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one	5
Knockdown of RFC3 enhances the sensitivity of colon cancer cells to oxaliplatin by inducing ferroptosis	5
Antimanic‐like effect of dipyridamole in the methylphenidate‐induced hyperlocomotion	5
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus	5
Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study	5
Thesis awards	5
	5
Pharmacokinetic and pharmacodynamic study of three products of epoetin alfa as single subcutaneous dose in healthy volunteers	5