Fundamental & Clinical Pharmacology

Papers
(The TQCC of Fundamental & Clinical Pharmacology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?51
Location matters: Overlooked ethnic‐geographic effect in China and Austria on propofol/cisatracurium sex differences among a population pharmacokinetic/pharmacodynamic (PopPK/PD) covariate analysis in50
Changes in digoxin pharmacokinetics associated with hepatic P‐glycoprotein upregulation in rats with non‐alcoholic fatty liver disease49
In vitro evidence that the vasorelaxant effects of 2‐nitro‐1‐phenyl‐1‐propanol on rat coronary arteries involve cyclic nucleotide pathways48
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin37
Protective Effects of Cannabis sativa on chemotherapy‐induced nausea in a rat: Involvement of CB1 receptors29
Can cannabidiol have an analgesic effect?28
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil27
Effect of ceftriaxone on intestinal transit time27
Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats20
Efficacy of COVID‐19 vaccines: Several modes of expression should be presented in scientific publications19
Inhibition of NorA efflux pump of Staphylococcus aureus by anacardic acids isolated from the cashew nutshell liquid of Anacardium occidentale L.17
Calcium dobesilate protects against d‐galactose‐induced hepatic and renal dysfunction, oxidative stress, and pathological damage17
Methylsulfonylmethane induces caspase‐dependent apoptosis in acute myeloid leukemia cell lines17
Roflumilast improves resolution of sepsis‐induced acute kidney injury by retarding late phase renal interstitial immune cells infiltration and leakage in urinary sediments17
Novel ginsenoside monomer RT4 promotes colitis repair in mice by regulating miR‐144‐3p/SLC7A11 signaling pathway16
MiR‐199a‐3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury16
Relative bioavailability and pharmacokinetic comparison of a fixed‐dose combination tablet of mosapride, pancreatin, and simethicone relative to single‐component mosapride tablets in healthy Mexican s15
Cell therapy procedure using anti‐inflammatory macrophage M2 can potentially reduce Clinical Score in animals with Experimental Autoimmune Encephalomyelitis: A preclinical systematic review and meta‐a14
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Precipitation of sugammadex with nicardipine and labetalol: A laboratory research14
Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy14
Treatment implications of augmented renal clearance in a critically ill COVID‐19 patient: A case report14
Tofacitinib improved peripheral endothelial dysfunction and brain‐derived neurotrophic factor levels in the rat adjuvant‐induced arthritis model12
Issue Information12
In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease12
Metformin improves neurobehavioral impairments of streptozotocin‐treated and western diet‐fed mice: Beyond glucose‐lowering effects12
Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer11
The protective effect of α7‐nACh receptor and its interaction with 5‐HT1B/1D receptors in acute intestinal ischemia‐reperfusion injury in rats11
Evaluation of anti‐inflammatory activity of kaurenol: Experimental evaluation and mechanistic insights11
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging11
Cover Image, Volume 36, Issue 110
Comparison of the effects of losartan, captopril, angiotensin II type 2 receptor agonist compound 21, and MAS receptor agonist AVE 0991 on myocardial ischemia‐reperfusion necrosis in rats10
Vestibular disorders following BNT162b2 mRNA COVID‐19 vaccination: A retrospective case series10
Sakuranetin exerts anticonvulsant effect in bicuculline‐induced seizures10
Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study)10
Spontaneous reporting of adverse drug reactions as an outlet for patient dismay? The case of Levothyrox® change of excipients10
Master 2 Award10
Chlorogenic acid co‐administration alleviates cisplatin‐induced peripheral neuropathy in rats9
UPLC‐MS analysis and network pharmacology‐based investigation into the active ingredients and molecular mechanisms of anti‐fatigue of male flowers with Eucommia ulmoides Oliv.9
Kappa‐opioid receptor‐mediated thermal analgesia evoked by the intrathecal administration of the chemokine CCL1 in mice9
Issue Information9
Acetazolamide suppresses the progression of hepatocellular carcinoma induced by diethylnitrosamine in Wistar albino rats9
Issue Information9
Sitagliptin's renoprotective effect in a diabetic nephropathy model in rats: The potential role of PI3K/AKT pathway9
Issue Information8
Histamine H1‐ and H2‐receptors participate to provide metabolic energy differently8
Discussed Poster Abstracts8
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Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities8
A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms7
Inhibition of plasminogen suppresses fibrosis and macrophage foaming in a nonalcoholic steatohepatitis mouse model7
Use of real‐world evidence in translational pharmacology research7
Differential expression and activities of cytochrome P450 3A in the rat brain microsomes and mitochondria7
Inhibition of kidney potassium channels by fluoxetine: In vivo and in vitro studies7
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Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis7
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Therapeutic targeting of DNA damage repair pathways guided by homologous recombination deficiency scoring in ovarian cancers7
Capivasertib augments chemotherapy via Akt inhibition in preclinical small cell lung cancer models7
Necrostatin‐1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice7
Vitamin D3 potentiates the nephroprotective effects of vildagliptin–metformin combination in a rat model of metabolic syndrome7
Bupivacaine inhibits the TLR4‐ and TLR2‐Myd88/NF‐κB pathways in human leukocytes7
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Anti‐oxidative and anti‐neuroinflammatory role of Necrostatin‐1s and docosahexaenoic acid in RIP‐1‐mediated neurotoxicity in MPTP‐induced Parkinson's disease model7
Issue Information7
A novel naphthylchalcone ([E]‐4‐(3‐[naphthalen‐2‐yl]‐3‐oxoprop‐1‐en‐1‐yl) induces intrinsic and extrinsic apoptosis in human acute leukemia cell lines7
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats7
Chemsex practice in France: An update in Addictovigilance data7
Effects of nalbuphine on the cardiotoxicity of ropivacaine in rats7
Animal models for the evaluation of antipsychotic agents7
Advances in the phytochemical screening and biological potential of propolis7
Effect of a high‐fat meal on the relative bioavailability of HMPL‐689 in Chinese healthy volunteers6
Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency6
Discussed Poster Abstracts – PM26
COVID‐19 in DMARD‐treated patients with inflammatory rheumatic diseases: Insights from an analysis of the World Health Organization pharmacovigilance database6
Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases6
Antihypertensive and lipid‐lowering drugs usage after primary stroke in a large representative sample of the French population6
Deliberation on debilitating condition of cancer cachexia: Skeletal muscle wasting6
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Update on monkeypox virus infection: Focusing current treatment and prevention approaches5
Recognition of potential therapeutic role of 2‐hydroxy‐3‐methylanthraquinones in the treatment of gallbladder carcinoma: A proteomics analysis5
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model5
Drug news and therapeutic news5
The effects of cannabidiol on subjective states, cognition, and psychomotor function in healthy adults: A randomized clinical trial5
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case5
Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes5
Lacosamide use during breastfeeding: A case report and a literature review5
LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice5
Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats5
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Drug‐induced radiation recall reactions and non‐anticancer drugs: A descriptive analysis from VigiBase®5
Oral Communication Abstracts5
Atorvastatin ameliorates α‐KGDH and GDH functions in rats with diet‐induced hypercholesterolemia5
Adrenaline enhances nociceptive and motor blockades by intrathecal carteolol and oxprenolol in rats5
Issue Information5
Master 2 award5
Probing polypharmacy, ageing and sex effects on physical function using different tests5
Chronic polypharmacy at all age: A population‐based drug utilization study5
Discussed Poster Abstracts – PM15
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Pharmacokinetic and pharmacodynamic study of three products of epoetin alfa as single subcutaneous dose in healthy volunteers5
Involvement of different K+ channel subtypes in hydrogen sulfide‐induced vasorelaxation of human internal mammary artery5
Prevalence of medication administration errors in hospitalized adults: A systematic review and meta‐analysis up to 2017 to explore sources of heterogeneity5
Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one5
Development of a Bayesian estimation tool to determine the optimal duration of apixaban discontinuation before a high‐bleeding risk procedure4
Vortioxetine improved schizophrenia‐like behavioral deficits in a Poly I:C‐induced maternal immune activation model of schizophrenia in rats4
Population pharmacokinetics of sivelestat in Chinese patients with severe pneumonia4
Trends in adverse drug reactions related to oral weak opioid analgesics in therapeutic use in adults: A 10‐year French vigilances retrospective study4
Issue Information4
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma4
Mechanism research on microRNA‐669f‐5p/deoxycytidylate deaminase axis mediating sevoflurane‐induced cognitive dysfunction in aged mice4
Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains4
Thesis awards4
JAK/STAT inhibitors mitigate sepsis‐associated cerebral and cognitive injury4
Angiotensin receptor–neprilysin inhibitor (thiorphan/irbesartan) improved cardiac function in a rat model of myocardial ischemic reperfusion injury4
Is lithium neuroprotective? An updated mechanistic illustrated review4
Buprenorphine exposures in adolescents and adults: A 10‐year experience of a French Poison Control Center4
Issue Information4
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice4
Issue Information4
Antimanic‐like effect of dipyridamole in the methylphenidate‐induced hyperlocomotion4
A mini‐review on anticancer‐related properties of azithromycin and its potential activities in overcoming the challenges of glioblastoma4
Analgesic switching in chronic users of dextropropoxyphene in France4
Inflammatory molecules facilitate the development of docetaxel‐resistant prostate cancer cells in vitro and in vivo4
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus 4
Interaction of buspirone and its major metabolites with human organic cation transporters4
Combination of human papillomaviruses L1 and L2 multiepitope constructs protects mice against tumor cells4
Knockdown of RFC3 enhances the sensitivity of colon cancer cells to oxaliplatin by inducing ferroptosis4
In vitro evidence that the anti‐inflammatory effect of synthetic cinnamate‐derived dienes is directly linked to a macrophage repolarization4
Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study4
Afatinib triggers a Ni2+‐resistant Ca2+ influx pathway in A549 non‐small cell lung cancer cells4
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