Fundamental & Clinical Pharmacology

Article	Citations
	70
Protective Effects of Cannabis sativa on chemotherapy‐induced nausea in a rat: Involvement of CB1 receptors	41
Preventive Effects of trans ‐4‐Methoxy‐β‐nitrostyrene on Monocrotaline‐Induced Pulmonary Arterial Hypertension in Rats	32
In vitro evidence that the vasorelaxant effects of 2‐nitro‐1‐phenyl‐1‐propanol on rat coronary arteries involve cyclic nucleotide pathways	31
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin	30
Can cannabidiol have an analgesic effect?	30
Use of Psychoactive Substances Before Incarceration Among Prison Inmates With Drug Abuse or Dependence: Data From the OPPIDUM Program	27
Inhibition of NorA efflux pump of Staphylococcus aureus by anacardic acids isolated from the cashew nutshell liquid of Anacardium occidentale L.	27
Effect of ceftriaxone on intestinal transit time	24
Improvement of cognitive dysfunction by a novel phosphodiesterase type 5 inhibitor, Tadalafil	21
	21
MiR‐199a‐3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury	20
Effects of FECH Gene Polymorphisms and Serum Ferrochelatase Levels on Antituberculosis Drug‐Induced Liver Injury in China	20
Effects of clarithromycin on the pharmacokinetics of tacrolimus and expression of CYP3A4 and P‐glycoprotein in rats	19
Novel ginsenoside monomer RT4 promotes colitis repair in mice by regulating miR‐144‐3p/SLC7A11 signaling pathway	19
Methylsulfonylmethane induces caspase‐dependent apoptosis in acute myeloid leukemia cell lines	18
	17
Metformin improves neurobehavioral impairments of streptozotocin‐treated and western diet‐fed mice: Beyond glucose‐lowering effects	16
Precipitation of sugammadex with nicardipine and labetalol: A laboratory research	16
Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy	16
Issue Information	16
Cell therapy procedure using anti‐inflammatory macrophage M2 can potentially reduce Clinical Score in animals with Experimental Autoimmune Encephalomyelitis: A preclinical systematic review and meta‐a	15
Treatment implications of augmented renal clearance in a critically ill COVID‐19 patient: A case report	14
French‐Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics	14
Master 2 Award	14

Vestibular disorders following BNT162b2 mRNA COVID‐19 vaccination: A retrospective case series	13
Issue Information	13
Real‐World Use of Dupilumab in Atopic Dermatitis: Observational Study Results Linked to SNDS	13
Histamine H1‐ and H2‐receptors participate to provide metabolic energy differently	13
Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer	13
Evaluation of anti‐inflammatory activity of kaurenol: Experimental evaluation and mechanistic insights	13
Issue Information	13
Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging	13
Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study)	12
Thesis awards	12
Master 2 award	12
	11
Chlorogenic acid co‐administration alleviates cisplatin‐induced peripheral neuropathy in rats	11
UPLC‐MS analysis and network pharmacology‐based investigation into the active ingredients and molecular mechanisms of anti‐fatigue of male flowers with Eucommia ulmoides Oliv.	11
Acetazolamide suppresses the progression of hepatocellular carcinoma induced by diethylnitrosamine in Wistar albino rats	11
JAK Inhibitors and Memory Impairment: Disproportionality Analyses in the WHO Global Pharmacovigilance Database, VigiBase	11
	10
Necrostatin‐1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice	10
A comprehensive view on the quercetin impact on bladder cancer: Focusing on oxidative stress, cellular, and molecular mechanisms	10
Theme and main topic index	10
Vitamin D lacks efficacy: A re‐analysis of a systematic review using the REB method	10
A novel naphthylchalcone ([E]‐4‐(3‐[naphthalen‐2‐yl]‐3‐oxoprop‐1‐en‐1‐yl) induces intrinsic and extrinsic apoptosis in human acute leukemia cell lines	10
Issue Information	10
Issue Information	10
The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats	10
Differential expression and activities of cytochrome P450 3A in the rat brain microsomes and mitochondria	10
	9
	9
Oral communication abstracts	9
Capivasertib augments chemotherapy via Akt inhibition in preclinical small cell lung cancer models	9
Therapeutic targeting of DNA damage repair pathways guided by homologous recombination deficiency scoring in ovarian cancers	9
Inhibition of kidney potassium channels by fluoxetine: In vivo and in vitro studies	9
	9
Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells	9
	9
Extracellular Remodeling, Tissue Fibrosis, and Clinical Translation	9
Issue Information	8
Atorvastatin‐Associated Liver Injury: Outcome After Statin Rechallenge	8
Prospective pilot study evaluating a vitamin D3 loading dose in critically ill children with vitamin D deficiency	8
Advances in the phytochemical screening and biological potential of propolis	8
Anti‐oxidative and anti‐neuroinflammatory role of Necrostatin‐1s and docosahexaenoic acid in RIP‐1‐mediated neurotoxicity in MPTP‐induced Parkinson's disease model	8
Animal models for the evaluation of antipsychotic agents	8
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case	8
	8
Bupivacaine inhibits the TLR4‐ and TLR2‐Myd88/NF‐κB pathways in human leukocytes	8
Association between immune‐related adverse events and prognosis in patients treated with immune checkpoint inhibitors in melanoma: A surrogacy analysis	8
Discussed Poster Abstracts – PM2	8
Involvement of different K+ channel subtypes in hydrogen sulfide‐induced vasorelaxation of human internal mammary artery	8
Atorvastatin ameliorates α‐KGDH and GDH functions in rats with diet‐induced hypercholesterolemia	7
Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases	7

Drug news and therapeutic news	7
Drug‐induced radiation recall reactions and non‐anticancer drugs: A descriptive analysis from VigiBase®	7
Master 2 award	7
Adrenaline enhances nociceptive and motor blockades by intrathecal carteolol and oxprenolol in rats	7
Deliberation on debilitating condition of cancer cachexia: Skeletal muscle wasting	7
The effects of cannabidiol on subjective states, cognition, and psychomotor function in healthy adults: A randomized clinical trial	7
Update on monkeypox virus infection: Focusing current treatment and prevention approaches	7
Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats	7
Tamsulosin Attenuates Cardiac Hypertrophy via Integrin‐Linked Kinase: Possible Mechanisms	7
Effect of a high‐fat meal on the relative bioavailability of HMPL‐689 in Chinese healthy volunteers	7
Discussed Poster Abstracts – PM1	7
Lacosamide use during breastfeeding: A case report and a literature review	7
Prevalence of medication administration errors in hospitalized adults: A systematic review and meta‐analysis up to 2017 to explore sources of heterogeneity	7
Issue Information	6
	6
JAK/STAT inhibitors mitigate sepsis‐associated cerebral and cognitive injury	6
SGLT‐2 Inhibitors Use in Hospitalized Patients in France: A Cross‐Sectional Study	6
Pharmacokinetic and pharmacodynamic study of three products of epoetin alfa as single subcutaneous dose in healthy volunteers	6
Relapse and New‐Onset of Autoimmune or Inflammatory Diseases Following Vaccination With SPIKEVAX: Pharmacovigilance Overview From the French Spontaneous Reported System	6
LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice	6
Analgesic switching in chronic users of dextropropoxyphene in France	6
Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains	6
Medical Cannabis Use in France: An Observational Safety Study Based on the RECANN Registry and the Pharmacovigilance/Addictovigilance System From 2021 to 2024	6
Oral Communication Abstracts	6
Probing polypharmacy, ageing and sex effects on physical function using different tests	6
	6
Nebivolol Mitigates the Pro‐Oxidative and Pro‐Inflammatory Effects of Cyclophosphamide in the Heart	6
Gabapentinoids and Neuropathic Pain: Evaluation of the Quality of Randomised Controlled Trials: An Umbrella Review	6
Mechanism research on microRNA‐669f‐5p/deoxycytidylate deaminase axis mediating sevoflurane‐induced cognitive dysfunction in aged mice	5
Angiotensin receptor–neprilysin inhibitor (thiorphan/irbesartan) improved cardiac function in a rat model of myocardial ischemic reperfusion injury	5
Population pharmacokinetics of sivelestat in Chinese patients with severe pneumonia	5
Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study	5
Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one	5
Afatinib triggers a Ni2+‐resistant Ca2+ influx pathway in A549 non‐small cell lung cancer cells	5
A mini‐review on anticancer‐related properties of azithromycin and its potential activities in overcoming the challenges of glioblastoma	5
Comparative Analysis of Intrathecal Lidocaine Combined With Guanfacine or Dexmedetomidine on Nociceptive and Motor Blockade in Rats	5
Thesis awards	5
Drug news and therapeutic news	5
Knockdown of RFC3 enhances the sensitivity of colon cancer cells to oxaliplatin by inducing ferroptosis	5
Antimanic‐like effect of dipyridamole in the methylphenidate‐induced hyperlocomotion	5
Pro‐inflammatory cytokines mediating senescence of vascular endothelial cells in atherosclerosis	4
Interaction of buspirone and its major metabolites with human organic cation transporters	4
Insights into nanostructured lipid carriers of etoricoxib for mitigating radiation‐induced lung inflammation and exploring anti‐inflammatory mechanisms in rats	4
Immunomodulatory effect of IL‐35 gene‐transfected mesenchymal stem cells on allergic asthma	4
Issue Information	4
No Impact of Vancomycin MIC, AUC, or AUC/MIC in Enterococcus faecium Bacteremia	4
Busulfan induces steatosis in HepaRG cells but not in primary human hepatocytes: Possible explanations and implication for the prediction of drug‐induced liver injury	4
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus	4
Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies	4
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice	4
Issue Information	4
Latest advances in the reversal strategies for direct oral anticoagulants	4
Cannabinoids and Adverse Convulsive Effects: A Pharmacovigilance and Addictovigilance Analysis of Cases Reported in France	4
Vortioxetine improved schizophrenia‐like behavioral deficits in a Poly I:C‐induced maternal immune activation model of schizophrenia in rats	4
Is lithium neuroprotective? An updated mechanistic illustrated review	4
Issue Information	4
Pharmacological treatment for mental health illnesses in adults receiving dialysis: A scoping review	4
	3
The protective effect of pregabalin and xanthenone on testicular ischemia/reperfusion injury in rats	3
Heterogeneity in protocols and outcomes to study the effect of renin‐angiotensin system blockers in inflammatory bowel disease: A systematic review	3
Alterations in the gene expression of SARS‐COV‐2 entry receptors and enzymes in lungs and hearts of controlled and uncontrolled diabetic mice	3
Effects of the nerve growth factor and its carrier protein on the inflammatory response from human monocytes	3
Issue Information	3
Correction to “ ABCB1 , SLC22A1 , COMT , and	3
Sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) plus glucagon‐like peptide type 1 receptor combination is more effective than SGLT2i plus dipeptidyl peptidase‐4 inhibitor combination in treating obe	3
Pentosan polysulfate exerts anti‐inflammatory effect and halts albuminuria progression in diabetic nephropathy: Role of combined losartan	3
Bezafibrate mitigates oxidized‐low density lipoprotein (ox‐LDL)‐induced the attachment of monocytes to endothelial cells: An implication in atherosclerosis	3
Factors Associated With Cocaine Use Disorder: Results From the French Nationwide Repeated Cross‐Sectional OPPIDUM Study (2019–2023)	3
Fundamental and Clinical Pharmacology of drug repositioning	3
Issue Information	3
KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury	3
FKA‐A NPs enhances PTX‐A NPs efficacy to suppress ovarian cancer via regulating Skp2/YAP pathway	3
Discussed Poster Abstracts	3
Drug Exposure in Chronic Kidney Disease: It Is Not Just About the Glomerular Filtration Rate	3
Glibenclamide promoted functional recovery following sciatic nerve injury in male Wistar rats	3
Author index	3
Intradermal testing of iodinated contrast media: Should we test up to pure or with diluted compounds only?	3
Exploring the therapeutic potential of Modafinil in mitigating renal ischemia–reperfusion injury in rats	3
Repurposing Asparaginase Therapy to Target Cisplatin‐Resistant Cancer Cells	3
Issue Information	3

Pre‐treatment or post‐treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion	3
The role of β‐adrenergic receptors in the regulation of cardiac tolerance to ischemia/reperfusion. Why do β‐adrenergic receptor agonists and antagonists protect the heart?	3
Residual Effects of Acute and Subchronic Zolpidem Treatments on Attentional Processes in Aged Female Rats	3
Discussed poster abstracts—PM1	3
DPD Ultra‐Rapid Metabolizer Status and Efficacy of 5‐Fluorouracil Treatment: A Real‐World Study	3
Alogliptin Delays the Healing of Traumatic Oral Ulcers in the Buccal Mucosa of Wistar Rats	3
Physiologically Based Pharmacokinetic modelling of drugs in pregnancy: A mini‐review on availability and limitations	3
Role of biomarkers and molecular signaling pathways in acute lung injury	3
	3
Theme and main topic index	3
Photobiological effect of eugenol‐derived 3‐benzoylcoumarin associated with led lights against MDR microorganisms	3
Hesperidin improves physiological outcomes in an arginine vasopressin rat model of pre‐eclampsia	3
Issue Information	3
Issue Information	3
Evaluation of potential antiviral activities of antimicrobial peptides in fish mucus	3
Prognostic roles of dysregulated METTL3 protein expression in cancers and potential anticancer value by inhibiting METTL3 function	3
Fluvoxamine Attenuates Liver Injury in Lipopolysaccharide‐Induced Sepsis: Via Nrf2/HO‐1 Pathway	3
Trends in adverse drug reactions related to oral weak opioid analgesics in therapeutic use in adults: A 10‐year French vigilances retrospective study	3
Investigating the link between drug consumption and adverse events reporting in France	3
Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction	2
Molecular mechanisms of Alzheimer's disease: From therapeutic targets to promising drugs	2
Exogenous GalR2‐specific peptide agonist as a tool for treating myocardial ischemia/reperfusion injury	2
Differential Antipyretic Effects of Toll‐Like Receptor 4 Signal Inhibitors in Male Rats	2
Isobolographic analysis of the ciprofloxacin–gentamicin combination against beta‐lactamase‐producing Staphylococcus aureus	2
The synergy between alkylating agents and ERCC1–XPF inhibitors is p53 dependent	2
Repurposing bosentan as an anticancer agent: EGFR/ERK/c‐Jun modulation inhibits NSCLC tumor growth	2
Issue Information	2
Myrtenal exhibits cardioprotective effects by attenuating the pathological progression associated with myocardial infarction	2
MNK/eIF4E inhibition overcomes anlotinib resistance in non‐small cell lung cancer	2
Discussed Poster Abstracts – PM1	2
Inhibitory effects and molecular mechanisms of ginsenoside Rg1 on the senescence of hematopoietic stem cells	2
Wnt/beta‐catenin modulation: A promising frontier in chronic kidney disease management	2
Adverse effects of gender‐affirming hormonal therapy in transgender persons: Assessing reports in the French pharmacovigilance database	2
Impacts of genetic polymorphisms and cancer cachexia on naldemedine pharmacokinetics and bowel movements in patients receiving opioid analgesics	2
Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice	2
Evidence that the anti‐inflammatory effect of 4‐aryl‐4H‐chromenes is linked to macrophage repolarization	2
The state of astragaloside IV research: A bibliometric and visualized analysis	2
Evaluating the Environmental Impact of Clinical Research: A Full Life Cycle Analysis of a French Academic Randomised Clinical Trial	2
Sodium hypochlorite accident diagnosis and management: Analysis from the literature and the French pharmacovigilance database	2
Issue Information	2
Role of angiotensin receptor blockers in the context of Alzheimer's disease	2
Issue Information	2
Challenges and opportunities of medicines for treating tendon inflammation and fibrosis: A comprehensive and mechanistic review	2
Induction of Ca 2+ signaling and cytotoxic responses of human lung fibroblasts upon an antihistamine drug oxatomide treatment and evaluating the prot	2
Breastfeeding and contrast agents—A critical review and presentation of new aspects	2
Chemsex in HIV pre‐exposure prophylaxis users: Assessment of mood disorders and addictive behavior	2
Opening of mitochondrial permeability transition pore in cardiomyocytes: Is ferutinin a suitable tool for its assessment?	2
Immunomodulatory effect of N‐acetyl‐seryl‐aspartyl‐proline and vasoactive intestinal peptide on chronic obstructive pulmonary disease pathophysiology	2