Biomedicine & Pharmacotherapy

Papers
(The TQCC of Biomedicine & Pharmacotherapy is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis528
The anti-fibrotic efficacy of adelmidrol depends on hepatic PPARγ levels521
Editorial Board355
Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm285
Editorial Board267
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells261
Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease232
Cervical carcinoma high expressed 1 (CCHE1): An oncogenic lncRNA in diverse neoplasms219
Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2216
A new IRES-mediated truncated Cx32 isoform inhibits global mRNA translation to suppress glioblastoma215
Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma212
Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane:A prospective observational study212
Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy212
Treprostinil reduces mitochondrial injury during rat renal ischemia-reperfusion injury211
Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis209
The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome205
Editorial Board195
Non-coding RNAs in metabolic reprogramming of bone and soft tissue sarcoma: Fundamental mechanism and clinical implication179
Therapeutic efficacy of 3,4-Diaminopyridine phosphate on neuromuscular junction in Pompe disease178
Editorial Board170
Between therapy effect and false-positive result in animal experimentation169
Salvadora persica attenuates DMBA-induced mammary cancer through downregulation oxidative stress, estrogen receptor expression and proliferation and augmenting apoptosis168
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons165
Simple ammonium salt and sigma-1 receptor ligand dipentylammonium provides neuroprotective effects in cell culture and Caenorhabditis elegans models of Alzheimer's disease159
Injectable Gel-PEG hydrogels as promising delivery system for intravitreal PACAP release: Novel therapeutics for unilateral common carotid artery occlusion induced retinal ischemia158
Corrigendum to: ’Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 3’ [Biomed. Pharmacother. (2023) 115176/165]156
Corrigendum to “CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells” [Biomed. Pharmacother.156
Corrigendum to “Secretory products of DPSC mitigate inflammatory effects in microglial cells by targeting MAPK pathway” Biomed. Pharmacother. 170(2024) 115971155
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation150
A phytotherapic blend immunity-6™ inhibits myeloid leukemic cells 2 activation involving purinergic signaling145
Venetoclax in adult acute myeloid leukemia144
Emerging role of carbon monoxide in intestinal transplantation144
“Aducanumab” making a comeback in Alzheimer’s disease: An old wine in a new bottle143
ACT001 inhibits primary central nervous system lymphoma tumor growth by enhancing the anti-tumor effect of T cells140
FM19G11-loaded nanoparticles modulate energetic status and production of reactive oxygen species in myoblasts from ALS mice135
Editorial Board135
Renal intrinsic cells remodeling in diabetic kidney disease and the regulatory effects of SGLT2 Inhibitors130
Sildenafil delays bone remodeling of fractured femora in aged mice by reducing the number and activity of osteoclasts within the callus tissue129
Amifostine loaded lipid-calcium carbonate nanoparticles as an oral drug delivery system for radiation protection129
Patient-derived tumor models in cancer research: Evaluation of the oncostatic effects of melatonin126
Excess iron intake induced liver injury: The role of gut-liver axis and therapeutic potential125
NADPH and NAC synergistically inhibits chronic ocular hypertension-induced neurodegeneration and neuroinflammation through regulating p38/MAPK pathway and peroxidation123
Development of alginate and alginate sulfate/polycaprolactone nanoparticles for growth factor delivery in wound healing therapy122
Retraction notice to “MiR-155–5p promotes oral cancer progression by targeting chromatin remodeling gene ARID2” [Biomed. Pharmacother. 122 (2020) 109696]120
Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction119
RETRACTED: mPEG-b-P(Glu-co-Phe) nanoparticles increase gastric retention time and gastric ulcer treatment efficacy of 20(S)-ginsenoside Rg3119
Exploring the anticancer effects of standardized extracts of poplar-type propolis: In vitro cytotoxicity toward cancer and normal cell lines117
Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis117
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice116
Neural crest-derived cells possess differentiation potential to keratinocytes in the process of wound healing115
Silencing tumor-intrinsic CD73 enhances the chemosensitivity of NSCLC and potentiates the anti-tumoral effects of cisplatin: An in vitro study115
Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate115
Tracking Chlamydia – Host interactions and antichlamydial activity in Caenorhabditis elegans113
Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy112
State of CD8+ T cells in progression from nonalcoholic steatohepatitis to hepatocellular carcinoma: From pathogenesis to immunotherapy110
A combined transcriptomics and proteomics approach to reveal the mechanism of AEE relieving hyperlipidemia in ApoE-/- mice109
Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation109
The role of ubiquitin-specific peptidases in glioma progression109
Resveratrol supplementation and acute pancreatitis: A comprehensive review109
Recent advances on European research in the field of "Biomedicine & Pharmacotherapy"108
Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function108
Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation107
Self-delivery nanodrug to manipulate tumor microenvironment for boosting photodynamic cancer immunotherapy106
The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapy104
Expression of concern: miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1 [Biomedicine & Pharmacotherapy 106 (2018) 1072–1081]103
Effects of emulsified and non-emulsified palm tocotrienol on bone and joint health in ovariectomised rats with monosodium iodoacetate-induced osteoarthritis103
Expression of concern: MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5- dependent PPAR signaling pathway [Bi103
A fungus-derived purpactin A as an inhibitor of TMEM16A chloride channels and mucin secretion in airway epithelial cells102
Expression of concern: MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury [Biome102
Retraction notice to “Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells” [Biomed. Pharmacother. 103 (2018) 947–954]102
Retraction notice to “Alkannin protects human renal proximal tubular epithelial cells from LPS-induced inflammatory injury by regulation of microRNA-210” [Biomed. Pharmacother. 108 (2018) 1679–1685]102
Longitudinal stability of molecular alterations and drug response profiles in tumor spheroid cell lines enables reproducible analyses99
Endoplasmic reticulum stress in intestinal microecology: A controller of antineoplastic drug-related cardiovascular toxicity98
Editorial Board98
Identification of curcumin analogues with anti-seizure potential in vivo using chemical and genetic zebrafish larva seizure models98
Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model96
Diabetes and hypertension: Pivotal involvement of purinergic signaling96
Retraction notice to “Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy” [Biomed. Pharmacot95
Retraction notice to "Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation" [Biomed. Pharmacoth94
Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice93
Retraction notice to “Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis” [Biomed. Pharmaco93
Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans93
Parecoxib improves atherosclerotic plaque stability by suppressing inflammation and inhibiting matrix metalloproteinases production93
Streptococcus thermophilus CNCM I-5570 lysate counteracts the aging process in human dermal fibroblast cells by neutralizing harmful free radicals and impacting antioxidant and anti-inflammatory pathw92
Kefir peptides mitigate L-NAME-induced preeclampsia in rats through modulating hypertension and endothelial dysfunction92
Zhen-Wu-Tang ameliorates lupus nephritis by diminishing renal tissue-resident memory CD8+ T cells via suppressing IL-15/STAT3 pathway92
Colchicine: Emerging therapeutic effects on atrial fibrillation by alleviating myocardial fibrosis in a rat model91
Tea (Camellia sinensis) ameliorates DSS-induced colitis and liver injury by inhibiting TLR4/NF-κB/NLRP3 inflammasome in mice91
In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response90
Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma p90
Beneficial effects of carvedilol modulating potassium channels on the control of glucose90
CXCL12 inhibits hair growth through CXCR489
Seroprevalence of SARS-CoV-2-specific antibodies and vaccination-related adverse events in systemic lupus erythematosus and rheumatoid arthritis89
919 granules improve postpartum depression through the regulation of abnormal peripheral blood IL-1β89
Physalin pool from Physalis angulata L. leaves and physalin D inhibit P2X7 receptor function in vitro and acute lung injury in vivo89
Phytochemicals targeting mitophagy: Therapeutic opportunities and prospects for treating Alzheimer’s disease88
Celastrol exerts antiarrhythmic effects in chronic heart failure via NLRP3/Caspase-1/IL-1β signaling pathway88
Multi-omics study reveals associations among neurotransmitter, extracellular vesicle-derived microRNA and psychiatric comorbidities during heroin and methamphetamine withdrawal88
The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis–associated liver tumors in a novel murine model87
Palbociclib promotes the antitumor activity of Venetoclax plus Azacitidine against acute myeloid leukemia87
A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives86
Fluoxetine ameliorates high-fat diet-induced metabolic abnormalities partially via reduced adipose triglyceride lipase-mediated adipocyte lipolysis86
Bacterial outer membrane vesicles in cancer: Biogenesis, pathogenesis, and clinical application86
Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice85
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC85
Antioxidant effects of Paeoniflorin and relevant molecular mechanisms as related to a variety of diseases: A review85
The involvement of NLRP3 inflammasome in the treatment of neurodegenerative diseases85
Elucidating cuproptosis in metabolic dysfunction-associated steatotic liver disease84
Dihydromyricetin treats pulmonary hypertension by modulating CKLF1/CCR5 axis-induced pulmonary vascular cell pyroptosis83
Antiseizure effects of Lilii Bulbus on pentylenetetrazol kindling-induced seizures in mice: Involvement of Reelin, Netrin-1, and semaphorin83
Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT751982
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway82
Impact of tumor suppressor genes inactivation on the multidrug resistance phenotype of hepatocellular carcinoma cells82
Cuproptosis in cancers: Function and implications from bench to bedside82
Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice82
Identification of early diagnostic biomarkers via WGCNA in gastric cancer82
Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review81
Potential roles of exosomes in the initiation and metastatic progression of lung cancer81
Unraveling the molecular and immunological landscape: Exploring signaling pathways in osteoporosis81
Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases81
The impact of curcumin on migraine: A comprehensive review80
Efficacy of Brazilian green propolis (EPP-AF®) as an adjunct treatment for hospitalized COVID-19 patients: A randomized, controlled clinical trial80
Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period80
Advance on combination therapy strategies based on biomedical nanotechnology induced ferroptosis for cancer therapeutics80
Clofazimine: A journey of a drug80
Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight80
GYY4137 attenuates functional impairment of corpus cavernosum and reduces fibrosis in rats with STZ-induced diabetes by inhibiting the TGF-β1/Smad/CTGF pathway80
Mannosylated polylactic-co-glycolic acid (MN-PLGA) nanoparticles induce potent anti-tumor immunity in murine model of breast cancer79
Inclisiran in lipid management: A Literature overview and future perspectives79
In situ administration of temperature-sensitive hydrogel composite loading paclitaxel microspheres and cisplatin for the treatment of melanoma79
Targeting the STAT3 oncogenic pathway: Cancer immunotherapy and drug repurposing79
Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice79
The role of the serotonergic system in atropine’s anti-myopic effects79
Si-Ni-San reverses dietary fat absorption defects in a murine model of depression79
T helper 17 (Th17) cell responses to the gut microbiota in human diseases79
Targeting mitochondria as a potential therapeutic strategy against chemoresistance in cancer78
Squalene nanoemulsion reinforces mucosal and immunological fingerprints following intravaginal delivery78
Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects77
Glycogen synthase kinase-3: A potential immunotherapeutic target in tumor microenvironment77
Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism77
Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells76
Necroptosis in Alzheimer’s disease: Potential therapeutic target76
CircRNA: An emerging star in the progression of glioma76
Overcoming drug delivery barriers and challenges in topical therapy of atopic dermatitis: A nanotechnological perspective76
Discovery of a novel NUAK1 inhibitor against pancreatic cancer76
Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities75
Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties75
Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications75
Induction of JAK2/STAT3 pathway contributes to protective effects of different therapeutics against myocardial ischemia/reperfusion75
Tomato (Solanum lycopersicum L.) seed: A review on bioactives and biomedical activities75
Effective-component compatibility of Bufei Yishen formula alleviates chronic obstructive pulmonary disease inflammation by regulating GSK3β-mediated NLRP3 inflammasome activation75
PD-L1 silencing inhibits triple-negative breast cancer development and upregulates T-cell-induced pro-inflammatory cytokines74
Basic research on curcumin in cervical cancer: Progress and perspectives74
Targeting hypoxia-related metabolism molecules: How to improve tumour immune and clinical treatment?74
Advances in the role and mechanism of miRNA in inflammatory pain74
Synergic effect of bone marrow derived mesenchymal stem cells and differentiated keratinocytes-like cells with a novel cellulose and collagen nanoscaffold on wound healing in rats73
Cinnarizine dissolving microneedles against microwave-induced brain injury73
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application73
Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesis73
4-thiazolidinone-based derivatives rosiglitazone and pioglitazone affect the expression of antioxidant enzymes in different human cell lines73
The pharmacokinetic property and pharmacological activity of acteoside: A review72
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis72
Analytical validation of a novel UHPLC-MS/MS method for 19 antibiotics quantification in plasma: Implementation in a LC-MS/MS Kit72
Mechanical stress abnormalities promote chondrocyte senescence - The pathogenesis of knee osteoarthritis71
Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs71
Glioblastoma targeting by water-soluble hypericin derivate HHL-PVP and photodynamic tumour killing71
Hippocampus kuda protein hydrolysate improves male reproductive dysfunction in diabetic rats71
Role of long noncoding RNAs in pathological cardiac remodeling after myocardial infarction: An emerging insight into molecular mechanisms and therapeutic potential71
Development of vericiguat: The first soluble guanylate cyclase (sGC) stimulator launched for heart failure with reduced ejection fraction (HFrEF)71
Engineering of the current nucleoside-modified mRNA-LNP vaccines against SARS-CoV-271
Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics71
PBMCs gene expression signature of advanced cirrhosis with high risk for clinically significant portal hypertension in HIV/HCV coinfected patients: A cross-control study71
The AhR/P38 MAPK pathway mediates kynurenine-induced cardiomyocyte damage: The dual role of resveratrol in apoptosis and autophagy71
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases70
Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review70
Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids70
Sesquiterpene lactones as potential therapeutic agents against Naegleria fowleri70
AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity70
The FAAH inhibitor URB597 reduces cocaine intake during conditioned punishment and mitigates cocaine seeking during withdrawal70
Polysaccharide-rich extract from Polygonatum sibiricum protects hematopoiesis in bone marrow suppressed by triple negative breast cancer70
Molecular insight into arrhythmogenic cardiomyopathy caused by DSG2 mutations70
Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway70
Ferroptosis: A novel therapeutic target of natural products against doxorubicin-induced cardiotoxicity69
Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches68
Granulocyte colony-stimulating factor in reproductive-related disease: Function, regulation and therapeutic effect68
Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders67
Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis67
Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer67
Mechanistic insights and perspectives involved in neuroprotective action of quercetin67
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs67
Erythropoietin-mediated IL-17 F attenuates sepsis-induced gut microbiota dysbiosis and barrier dysfunction66
Lactobacillus Casei-fermented Amomum Xanthioides Mitigates non-alcoholic fatty liver disease in a high-fat diet mice model66
Discovery of a synthetic taiwaniaquinoid with potent in vitro and in vivo antitumor activity against breast cancer cells66
Puerarin: a potential natural neuroprotective agent for neurological disorders66
Microbiota-derived short chain fatty acids: Their role and mechanisms in viral infections66
Toll-like receptor 4: A potential therapeutic target for multiple human diseases66
Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles66
Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs66
Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling65
Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study64
Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes64
Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction64
Revolutionizing cancer treatment: The power of dendritic cell-based vaccines in immunotherapy64
Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics64
ABCB1 genetic polymorphisms affect opioid requirement by altering function of the intestinal P-glycoprotein63
Angiotensin-converting enzyme inhibitors and statins therapies-induced changes in omics profiles in humans and transgenic tau mice63
Effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors, dapagliflozin and canagliflozin, on the musculoskeletal system in an experimental model of diabetes induced by high-fat diet and streptozo63
Modulatory mechanisms of cannabinoids as a window of hope to patients with sleep-related cardiometabolic risk63
Enhancing the biopharmaceutical attributes of atorvastatin calcium using polymeric and lipid-polymer hybrid nanoparticles: An approach for atherosclerosis treatment63
Editorial Board62
Activation of renal CSE/H2S pathway by alpha-lipoic acid protects against histological and functional changes in the diabetic kidney62
Editorial Board62
Amazonian medicinal plants efficiently inactivate Herpes and Chikungunya viruses62
The neuroimmune mechanism of pain induced depression in psoriatic arthritis and future directions62
Tricaprin can prevent the development of AAA by attenuating aortic degeneration62
Treatment of neovascular age-related macular degeneration within 48 h from diagnosis improves long-term functional outcome62
Comparative evaluation of doxorubicin, cyclophosphamide, 5-fluorouracil, and cisplatin on cognitive dysfunction in rats: Delineating the role of inflammation of hippocampal neurons and hypothyroidism61
DA-9805 protects dopaminergic neurons from endoplasmic reticulum stress and inflammation61
The traditional Chinese medicine formula Fufang-Zhenzhu-Tiaozhi protects myocardia from injury in diabetic minipigs with coronary heart disease61
The effect of lipid metabolism on cuproptosis-inducing cancer therapy60
Gut microbiota as the critical correlation of polycystic ovary syndrome and type 2 diabetes mellitus60
Nanobody-based CAR T cells targeting intracellular tumor antigens60
Advances of M1 macrophages-derived extracellular vesicles in tumor therapy60
Future prospects of ketoprofen in improving the safety of the gastric mucosa60
13-Methylpalmatine improves myocardial infarction injury by inhibiting CHOP-mediated cross-talk between endoplasmic reticulum and mitochondria60
Health promoting benefits of pongamol: An overview60
COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality59
Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis59
Biomedicine and pharmacotherapeutic effectiveness of combinatorial atorvastatin and quercetin on diabetic nephropathy: An in vitro study59
Ursodeoxycholic acid ameliorates cell migration retarded by the SARS-CoV-2 spike protein in BEAS-2B human bronchial epithelial cells59
Emerging role of LINC00461 in cancer59
The effects and mechanism of Kangfuxin on improving healing quality and preventing recurrence of gastric ulcer59
Evaluating the safety and efficiency of nanomaterials: A focus on mitochondrial health59
Multifaceted entrancing role of glucose and its analogue, 2-deoxy-D-glucose in cancer cell proliferation, inflammation, and virus infection58
De novo interleukin-10 production primed by Lactobacillus sakei CVL-001 amplifies the immunomodulatory abilities of mesenchymal stem cells to alleviate colitis58
Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism58
Diterpene promptly executes a non-canonical autophagic cell death in doxorubicin-resistant lung cancer58
Rosemary extract activates oligodendrogenesis genes in mouse brain and improves learning and memory ability58
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway58
Long non-coding RNAs as pathophysiological regulators, therapeutic targets and novel extracellular vesicle biomarkers for the diagnosis of inflammatory bowel disease58
A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation57
Preclinical toxicological study of long-circulating and fusogenic liposomes co-encapsulating paclitaxel and doxorubicin in synergic ratio57
Podocyte programmed cell death in diabetic kidney disease: Molecular mechanisms and therapeutic prospects57
Advances in the molecular mechanisms of statins in regulating endothelial nitric oxide bioavailability: Interlocking biology between eNOS activity and L-arginine metabolism57
Psycho-cardiology therapeutic effects of Shuangxinfang in rats with depression-behavior post acute myocardial infarction: Focus on protein S100A9 from proteomics56
Targeting ROCK1 in diabetic kidney disease: Unraveling mesangial fibrosis mechanisms and introducing myricetin as a novel antagonist56
Melittin treatment suppressed malignant NSCLC progression through enhancing CTSB-mediated hyperautophagy56
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis56
Naringenin regulates gut microbiota and SIRT1/ PGC-1ɑ signaling pathway in rats with letrozole-induced polycystic ovary syndrome56
Chemical compositions and experimental and computational modeling activity of sea cucumber Holothuria parva ethanolic extract against herpes simplex virus type 156
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