Biomedicine & Pharmacotherapy

Papers
(The H4-Index of Biomedicine & Pharmacotherapy is 81. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
The emerging role of ferroptosis in inflammation349
Cancer immunotherapy: Pros, cons and beyond329
Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management295
The role of IL-1β and TNF-α in intervertebral disc degeneration278
Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols261
Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases256
Type II diabetes mellitus: a review on recent drug based therapeutics247
Adipose tissue and insulin resistance in obese240
EMT, cancer stem cells and autophagy; The three main axes of metastasis228
Isorhamnetin: A review of pharmacological effects216
New understanding of the damage of SARS-CoV-2 infection outside the respiratory system212
5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition205
An update on β-sitosterol: A potential herbal nutraceutical for diabetic management194
ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19174
Lipase Inhibitors for Obesity: A Review171
WNT/β-catenin signaling in the development of liver cancers170
The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators163
Propolis and its potential against SARS-CoV-2 infection mechanisms and COVID-19 disease162
Anticancer activities of TCM and their active components against tumor metastasis161
Role of lncRNA LUCAT1 in cancer160
Antiviral activities of flavonoids159
Myricetin: A review of the most recent research156
Natural carbon-based quantum dots and their applications in drug delivery: A review153
Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation153
Antiproliferative and palliative activity of flavonoids in colorectal cancer152
The role of curcumin in aging and senescence: Molecular mechanisms148
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms144
Resveratrol (RV): A pharmacological review and call for further research140
Puerarin inhibits inflammation and oxidative stress in dextran sulfate sodium-induced colitis mice model139
Role of microbiota-derived short-chain fatty acids in cancer development and prevention135
Oxindole and its derivatives: A review on recent progress in biological activities132
Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role129
Composite probiotics alleviate type 2 diabetes by regulating intestinal microbiota and inducing GLP-1 secretion in db/db mice128
Exosomes as drug carriers for cancer therapy and challenges regarding exosome uptake127
Role of the NLRP3 inflammasome in autoimmune diseases124
Immune boosting functional foods and their mechanisms: A critical evaluation of probiotics and prebiotics120
The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review119
Lipocalin-2: Structure, function, distribution and role in metabolic disorders118
Monoclonal antibody as a potential anti-COVID-19117
The therapeutic effect of resveratrol: Focusing on the Nrf2 signaling pathway116
A review on the potential of Resveratrol in prevention and therapy of diabetes and diabetic complications116
MicroRNA: A signature for cancer progression115
Immune defence to invasive fungal infections: A comprehensive review115
Mechanistic insights and perspectives involved in neuroprotective action of quercetin113
Natural history of COVID-19 and current knowledge on treatment therapeutic options111
Probiotics for cancer alternative prevention and treatment107
Role of microbiota-derived short-chain fatty acids in nervous system disorders106
Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways106
New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities103
Innate and adaptive immune responses against coronavirus102
Investigation of gut microbiome changes in type 1 diabetic mellitus rats based on high-throughput sequencing102
Pleotropic Effects of Polyphenols in Cardiovascular System101
Flavonoids against the SARS-CoV-2 induced inflammatory storm101
AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation98
Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence97
NF-κB inhibitors in treatment and prevention of lung cancer96
Insights into antiviral mechanisms of remdesivir, lopinavir/ritonavir and chloroquine/hydroxychloroquine affecting the new SARS-CoV-295
CAR-macrophage: A new immunotherapy candidate against solid tumors95
Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents95
Mechanisms of BCG in the treatment of bladder cancer-current understanding and the prospect94
A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects92
Potential inhibitory effect of lycopene on prostate cancer92
Protection against COVID-19 injury by qingfei paidu decoction via anti-viral, anti-inflammatory activity and metabolic programming91
Mechanisms of blue light-induced eye hazard and protective measures: a review90
Melatonin regulates Aβ production/clearance balance and Aβ neurotoxicity: A potential therapeutic molecule for Alzheimer’s disease90
Novel advances in inhibiting advanced glycation end product formation using natural compounds89
Gestational diabetes mellitus - A metabolic and reproductive disorder89
Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/ inflammation pathway89
A comprehensive review on Pueraria: Insights on its chemistry and medicinal value88
Progress of exosomes in the diagnosis and treatment of lung cancer88
STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stress87
Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential86
The links between gut microbiota and obesity and obesity related diseases86
Ginsenosides for the treatment of metabolic syndrome and cardiovascular diseases: Pharmacology and mechanisms85
Clinical retrospective study on the efficacy of Qingfei Paidu decoction combined with Western medicine for COVID-19 treatment85
Polymer-hybrid nanoparticles: Current advances in biomedical applications84
Traditional Chinese medicine and lung cancer——From theory to practice84
Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages84
Folic acid (FA)-conjugated mesoporous silica nanoparticles combined with MRP-1 siRNA improves the suppressive effects of myricetin on non-small cell lung cancer (NSCLC)83
Biomedical applications of metallic nanoparticles in cancer: Current status and future perspectives83
Pharmacological basis and new insights of taxifolin: A comprehensive review82
Modified citrus pectin ameliorates myocardial fibrosis and inflammation via suppressing galectin-3 and TLR4/MyD88/NF-κB signaling pathway81
EF24 induces ferroptosis in osteosarcoma cells through HMOX181
Polysaccharides from Polygonatum kingianum improve glucose and lipid metabolism in rats fed a high fat diet81
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