Biomedicine & Pharmacotherapy

Papers
(The H4-Index of Biomedicine & Pharmacotherapy is 84. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
An update on β-sitosterol: A potential herbal nutraceutical for diabetic management453
Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management406
Adipose tissue and insulin resistance in obese360
The role of IL-1β and TNF-α in intervertebral disc degeneration335
Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases329
Type II diabetes mellitus: a review on recent drug based therapeutics327
EMT, cancer stem cells and autophagy; The three main axes of metastasis284
5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition270
Antiviral activities of flavonoids205
Resveratrol (RV): A pharmacological review and call for further research203
Anticancer activities of TCM and their active components against tumor metastasis201
WNT/β-catenin signaling in the development of liver cancers201
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms199
Role of lncRNA LUCAT1 in cancer197
ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19189
Myricetin: A review of the most recent research189
The role of curcumin in aging and senescence: Molecular mechanisms187
The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators181
Antiproliferative and palliative activity of flavonoids in colorectal cancer179
Propolis and its potential against SARS-CoV-2 infection mechanisms and COVID-19 disease178
Natural carbon-based quantum dots and their applications in drug delivery: A review178
Role of microbiota-derived short-chain fatty acids in cancer development and prevention174
Oxindole and its derivatives: A review on recent progress in biological activities166
Lipocalin-2: Structure, function, distribution and role in metabolic disorders164
The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review164
MicroRNA: A signature for cancer progression155
Mechanistic insights and perspectives involved in neuroprotective action of quercetin148
AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation145
Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents140
Gestational diabetes mellitus - A metabolic and reproductive disorder136
Role of microbiota-derived short-chain fatty acids in nervous system disorders134
Novel advances in inhibiting advanced glycation end product formation using natural compounds125
CAR-macrophage: A new immunotherapy candidate against solid tumors124
New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities122
Silica nanoparticles: Biomedical applications and toxicity118
Innate and adaptive immune responses against coronavirus117
The links between gut microbiota and obesity and obesity related diseases117
Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects115
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis115
Gene therapy clinical trials, where do we go? An overview114
Melatonin regulates Aβ production/clearance balance and Aβ neurotoxicity: A potential therapeutic molecule for Alzheimer’s disease113
Traditional Chinese medicine and lung cancer——From theory to practice112
Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence112
Cellular Red-Ox system in health and disease: The latest update111
Biomedical applications of metallic nanoparticles in cancer: Current status and future perspectives108
Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities108
Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs108
Pharmacological basis and new insights of taxifolin: A comprehensive review106
Progress of exosomes in the diagnosis and treatment of lung cancer106
A comprehensive review on Pueraria: Insights on its chemistry and medicinal value106
Polymer-hybrid nanoparticles: Current advances in biomedical applications106
Flavonoids against the SARS-CoV-2 induced inflammatory storm105
Ginsenosides for the treatment of metabolic syndrome and cardiovascular diseases: Pharmacology and mechanisms105
Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential105
Insights into antiviral mechanisms of remdesivir, lopinavir/ritonavir and chloroquine/hydroxychloroquine affecting the new SARS-CoV-2104
Emerging role of NRF2 in ROS-mediated tumor chemoresistance102
Intestinal barrier damage, systemic inflammatory response syndrome, and acute lung injury: A troublesome trio for acute pancreatitis101
Polyphenols inhibiting MAPK signalling pathway mediated oxidative stress and inflammation in depression101
Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/ inflammation pathway97
EF24 induces ferroptosis in osteosarcoma cells through HMOX196
Recent progress in TGF-β inhibitors for cancer therapy96
Plant-derived bioactive compounds in colon cancer treatment: An updated review95
Sodium-glucose co-transporter-2 (SGLT-2) inhibition reduces glucose uptake to induce breast cancer cell growth arrest through AMPK/mTOR pathway95
Tumor-infiltrating lymphocytes: Warriors fight against tumors powerfully95
MicroRNAs in Alzheimer's disease: Potential diagnostic markers and therapeutic targets95
The initiation of oxidative stress and therapeutic strategies in wound healing94
The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling91
Oxidative stress – Complex pathological issues concerning the hallmark of cardiovascular and metabolic disorders90
Pharmacological insights and prediction of lead bioactive isolates of Dita bark through experimental and computer-aided mechanism90
The role of miRNAs in colorectal cancer progression and chemoradiotherapy89
Traditional Chinese medicine combined with pulmonary drug delivery system and idiopathic pulmonary fibrosis: Rationale and therapeutic potential89
Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential88
Uric acid aggravates myocardial ischemia–reperfusion injury via ROS/NLRP3 pyroptosis pathway88
The antioxidant potential of different edible and medicinal mushrooms88
Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement88
Prospective multifunctional roles and pharmacological potential of dietary flavonoid narirutin88
Pharmacological effects and mechanisms of tannic acid87
Role of miRNA and lncRNAs in organ fibrosis and aging86
Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets86
Aptamers used for biosensors and targeted therapy85
A review on development of MUC1-based cancer vaccine85
Efficacy of Brazilian green propolis (EPP-AF®) as an adjunct treatment for hospitalized COVID-19 patients: A randomized, controlled clinical trial85
Exploring the multifocal role of phytochemicals as immunomodulators84
Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation84
Tetramethylpyrazine: A review on its mechanisms and functions84
Dual role of microbiota-derived short-chain fatty acids on host and pathogen84
Glutamate excitotoxicity: Potential therapeutic target for ischemic stroke84
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