OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pineal Research is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Melatonin prevents neuroinflammation and relieves depression by attenuating autophagy impairment through FOXO3a regulation	182
Melanopic illuminance defines the magnitude of human circadian light responses under a wide range of conditions	133
Melatonin attenuates diabetic cardiomyopathy and reduces myocardial vulnerability to ischemia‐reperfusion injury by improving mitochondrial quality control: Role of SIRT6	108
Melatonin attenuates choroidal neovascularization by regulating macrophage/microglia polarization via inhibition of RhoA/ROCK signaling pathway	99
Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury‐induced ferroptosis	99
Melatonin protects mouse testes from palmitic acid‐induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1‐dependent manner	97
Melatonin confers cadmium tolerance by modulating critical heavy metal chelators and transporters in radish plants	89
Circadian rhythms and obesity: Timekeeping governs lipid metabolism	81
Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer’s disease	71
Melatonin inhibits seed germination by crosstalk with abscisic acid, gibberellin, and auxin in Arabidopsis	62
Extracellular vesicles derived from melatonin‐preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2	59
Measuring melatonin by immunoassay	57
Melatonin reshapes the mitochondrial network and promotes intercellular mitochondrial transfer via tunneling nanotubes after ischemic‐like injury in hippocampal HT22 cells	54
Clinical trial to test the efficacy of melatonin in COVID‐19	53
Melatonin mitigates aflatoxin B1‐induced liver injury via modulation of gut microbiota/intestinal FXR/liver TLR4 signaling axis in mice	48
Melatonin inhibits lung cancer development by reversing the Warburg effect via stimulating the SIRT3/PDH axis	47
Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans	46
Melatonin restores neutrophil functions and prevents apoptosis amid dysfunctional glutathione redox system	46
Melatonin effects on bone: Implications for use as a therapy for managing bone loss	44
A novel melatonin‐regulated lncRNA suppresses TPA‐induced oral cancer cell motility through replenishing PRUNE2 expression	43
Safety of higher doses of melatonin in adults: A systematic review and meta‐analysis	43
Melatonin ameliorates PM_2.5‐induced cardiac perivascular fibrosis through regulating mitochondrial redox homeostasis	43
Melatonin improves the effect of cryopreservation on human oocytes by suppressing oxidative stress and maintaining the permeability of the oolemma	41
Melatonin receptor ligands: A pharmaco‐chemical perspective	39
Melatonin reduces nanoplastic uptake, translocation, and toxicity in wheat	38

Melatonin mitigates disrupted circadian rhythms, lowers intraocular pressure, and improves retinal ganglion cells function in glaucoma	36
Melatonin ameliorates aortic valve calcification via the regulation of circular RNA CircRIC3/miR‐204‐5p/DPP4 signaling in valvular interstitial cells	36
Weekly, seasonal, and chronotype‐dependent variation of dim‐light melatonin onset	36
Melatonin controversies, an update	35
Melatonin directly binds and inhibits death‐associated protein kinase 1 function in Alzheimer’s disease	35
Melatonin protects against thoracic aortic aneurysm and dissection through SIRT1‐dependent regulation of oxidative stress and vascular smooth muscle cell loss	34
Changing color and intensity of LED lighting across the day impacts on circadian melatonin rhythms and sleep in healthy men	34
Predicting melatonin suppression by light in humans: Unifying photoreceptor‐based equivalent daylight illuminances, spectral composition, timing and duration of light exposure	34
A meta‐analysis of microRNA networks regulated by melatonin in cancer: Portrait of potential candidates for breast cancer treatment	31
The interplay between mast cells, pineal gland, and circadian rhythm: Links between histamine, melatonin, and inflammatory mediators	30
Melatonin and other indoles show antiviral activities against swine coronaviruses in vitro at pharmacological concentrations	29
Melatonin protects inner retinal neurons of newborn mice after hypoxia‐ischemia	29
Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of cyclin‐dependent‐like kinase 5	28
The dual roles of melatonin biosynthesis enzymes in the coordination of melatonin biosynthesis and autophagy in cassava	28
Melatonin restores the pluripotency of long‐term‐cultured embryonic stem cells through melatonin receptor‐dependent m6A RNA regulation	28
Modeling melanopsin‐mediated effects of light on circadian phase, melatonin suppression, and subjective sleepiness	27
Switching diseased cells from cytosolic aerobic glycolysis to mitochondrial oxidative phosphorylation: A metabolic rhythm regulated by melatonin?	27
The association between melatonin and episodic migraine: A pilot network meta‐analysis of randomized controlled trials to compare the prophylactic effects with exogenous melatonin supplementation and	27
Melatonin‐triggered post‐transcriptional and post‐translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma	27
S‐cone contribution to the acute melatonin suppression response in humans	27
Melatonin improves uterine‐conceptus interaction via regulation of SIRT1 during early pregnancy	27
Whole‐genome sequence data of Hypericum perforatum and functional characterization of melatonin biosynthesis by N‐acetylserotonin O‐methyltransferase	27
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics	27
Melatonin synthesis genes N‐acetylserotonin methyltransferases evolved into caffeic acid O‐methyltransferases and both assisted in plant terrestrialization	26
Pan‐cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer	25
Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective	25
Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR‐135b‐3p/TOX3 axis	24
Journal of Pineal Research guideline for authors: Measuring melatonin in humans	24
Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport	24
Melatonin delays dark‐induced leaf senescence by inducing miR171b expression in tomato	23
Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model	23
The melatonin metabolite N1‐acetyl‐5‐methoxykynuramine facilitates long‐term object memory in young and aging mice	23
Early chronotype with advanced activity rhythms and dim light melatonin onset in a rural population	23
Single‐cell transcriptomic analysis reveals circadian rhythm disruption associated with poor prognosis and drug‐resistance in lung adenocarcinoma	22
The potential remedy of melatonin on osteoarthritis	22
Exogenous melatonin decreases circadian misalignment and body weight among early types	21
Melatonin promotes regeneration of injured motor axons via MT₁ receptors	20
The phytomelatonin receptor PMTR1 regulates seed development and germination by modulating abscisic acid homeostasis in Arabidopsis thaliana	20
Melatonin rescues the reproductive toxicity of low‐dose glyphosate‐based herbicide during mouse oocyte maturation via the GPER signaling pathway	20
Recharge of chondrocyte mitochondria by sustained release of melatonin protects cartilage matrix homeostasis in osteoarthritis	20
Treatment of isolated REM sleep behavior disorder using melatonin as a chronobiotic	20
Therapeutic potential of melatonin and melatonergic drugs on K18‐hACE2 mice infected with SARS‐CoV‐2	19
Mitochondrial function is controlled by melatonin and its metabolites in vitro in human melanoma cells	19
High sensitivity of melatonin suppression response to evening light in preschool‐aged children	19
In‐person vs home schooling during the COVID‐19 pandemic: Differences in sleep, circadian timing, and mood in early adolescence	19
Robust stability of melatonin circadian phase, sleep metrics, and chronotype across months in young adults living in real‐world settings	18
Melatonin alleviates the heat stress‐induced impairment of Sertoli cells by reprogramming glucose metabolism	18
Melatonin functions as a broad‐spectrum antifungal by targeting a conserved pathogen protein kinase	17
Melatonin modulates Nrf2 activity to protect porcine pre‐pubertal Sertoli cells from the abnormal H₂O₂ generation and reductive stress effects of cadmium	17
Melatonin promotes potassium deficiency tolerance by regulating HAK1 transporter and its upstream transcription factor NAC71 in wheat	17

Melatonin and the health of menopausal women: A systematic review	17
Melatonin reverses the loss of the anticontractile effect of perivascular adipose tissue in obese rats	17
Disrupted nocturnal melatonin in autism: Association with tumor necrosis factor and sleep disturbances	17
Melatonin mediates reactive oxygen species homeostasis via SlCV to regulate leaf senescence in tomato plants	17
Dysfunction of serotonergic activity and emotional responses across the light‐dark cycle in mice lacking melatonin MT₂ receptors	17
Nociceptive responses in melatonin MT₂ receptor knockout mice compared to MT₁ and double MT₁/MT₂ receptor knockout mice	16
Melatonin pretreatment alleviates the long‐term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor‐mediated Wnt signaling modulation	16