Journal of Pineal Research

Article	Citations
Zygotic Exposure to Venlafaxine Disrupts the Circadian Locomotor Activity Behaviour in Zebrafish Larvae	130
Correction to high sensitivity of melatonin suppression response to evening light in preschool‐aged children	103
RETRACTION: Changes in the Expression of Melatonin Receptors Induced by Melatonin Treatment in Hepatocarcinoma HepG2 Cells	91
Melatonin targets MoIcl1 and works synergistically with fungicide isoprothiolane in rice blast control	84
Melatonin Increased Autophagy Level to Facilitate Osteogenesis of Inflamed PDLSCs Through TMEM110 Signaling Pathways	74
BPS‐induced ovarian dysfunction: Protective actions of melatonin via modulation of SIRT‐1/Nrf2/NFĸB and IR/PI3K/pAkt/GLUT‐4 expressions in adult golden hamster	62
A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensi	58
Melatonin mediates reactive oxygen species homeostasis via SlCV to regulate leaf senescence in tomato plants	54
Melatonin inhibits chondrosarcoma cell proliferation and metastasis by enhancing miR‐520f‐3p production and suppressing MMP7 expression	54
Melatonin as a chronobiotic/cytoprotective agent in bone. Doses involved	54
From Seasonality to Species Conservation: Chronobiological Research on European Hamsters in Strasbourg, France	51
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Investigating the safety profiles of exogenous melatonin and associated adverse events: A pharmacovigilance study using WHO‐VigiBase	39
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L‐formate axis	39
Endogenous circadian regulation and phase resetting of clinical metabolic biomarkers	39
Light‐Dependent Circadian Rhythm Governs O‐GlcNAc Cycling to Influence Cognitive Function in Adult Zebrafish	36
Optimizing the Time and Dose of Melatonin as a Sleep‐Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose−Response Meta‐Analysis	35
Melatonin Ameliorates Atherosclerotic Plaque Vulnerability by Regulating PPARδ‐Associated Smooth Muscle Cell Phenotypic Switching	34
Erratum to: Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin‐induced apoptosis in neural cancer cells	34
No association between a common type 2 diabetes risk gene variant in the melatonin receptor gene (MTNR1B) and mortality among type 2 diabetes patients	33
Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model	33
Predicting melatonin suppression by light in humans: Unifying photoreceptor‐based equivalent daylight illuminances, spectral composition, timing and duration of light exposure	32
Melatonin treatment improves ventricular conduction via upregulation of Nav1.5 channel proteins and sodium current in the normal rat heart	32

Correction to “Melatonin mediates selenium‐induced tolerance to cadmium stress in tomato plants”	32
Melatonin prevents EAAC1 deletion‐induced retinal ganglion cell degeneration by inhibiting apoptosis and senescence	31
RETRACTION: Melatonin Inhibits the Expression of the Inducible Isoform of Nitric Oxide Synthase and Nuclear Factor Kappa B Activation in Rat Skeletal Muscle	29
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Light Environment of Arctic Solstices is Coupled With Melatonin Phase‐Amplitude Changes and Decline of Metabolic Health	29
Effect of melatonin cream on acute radiation dermatitis in patients with primary breast cancer: A double‐blind, randomized, placebo‐controlled trial	28
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3‐Month Melatonin Supplementation to Reduce Brain Oxidative Stress and Improve Sleep in Mild Cognitive Impairment: A Randomised Controlled Feasibility Trial	28
From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin	27
Melatonin improves skin barrier damage caused by sleep restriction through gut microbiota	27
Fetal malnutrition is associated with impairment of endogenous melatonin synthesis in pineal via hypermethylation of promoters of protein kinase C alpha and cAMP response element‐binding	26
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Effect of melatonin on ATG2B‐mediated autophagy regulation in sheep granulosa cells with different FecB genotypes	25
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics	25
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Homeobox gene‐encoded transcription factors in development and mature circadian function of the rodent pineal gland	25
Melatonin Rescues Influenza A Virus–Induced Cellular Energy Exhaustion via OMA1‐OPA1‐S in Acute Exacerbation of COPD	24
Orphan GPR50 Restrains Neurite Outgrowth and Cell Migration by Activating the G12/13 Protein‐RhoA Pathway in Neural Progenitor Cells and Tanycytes	24
Multi‐Omics Analysis Reveals That AhNHL Contributes to Melatonin‐Mediated Cadmium Tolerance in Peanut Plants	23
Single‐cell transcriptomic analysis reveals circadian rhythm disruption associated with poor prognosis and drug‐resistance in lung adenocarcinoma	22
Enhanced anti‐angiogenic activity of novel melatonin‐like agents	22
In Vitro and In Vivo Effects of Melatonin‐Containing Combinations in Human Pancreatic Ductal Adenocarcinoma	22
Protective Effects of Melatonin on Kidney Function Against Contrast Media‐Induced Kidney Damage in Patients With Chronic Kidney Disease: A Prospective, Randomized, Double‐Blinded, Placebo‐Controlled T	21
Mouse Models in Circadian Rhythm and Melatonin Research	21
Melatonin Affects Peucedanum praeruptorum Vegetative Growth and Coumarin Synthesis by Modulating the Antioxidant System, Photosynthesis, and Endogenous Hormones	21
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Relating Photoperiod and Outdoor Temperature With Sleep Architecture in Patients With Neuropsychiatric Sleep Disorders	20
Melatonin augments the neuroprotective effects of hypothermia in lambs following perinatal asphyxia	19
Melatonin as a key regulator in seed germination under abiotic stress	19
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Photoperiod integration in C3H rd1 mice	18
Melatonin Alleviates Osteoarthritis by Regulating NADPH Oxidase 4–Induced Ferroptosis and Mitigating Mitochondrial Dysfunction	18
Correction to “Melatonin/PGC1A/UCP1 promotes tumor slimming and represses tumor progression by initiating autophagy and lipid browning”	18
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Melatonin Inhibits Endometriosis Growth via Specific Binding and Inhibition of EGFR Phosphorylation	18
Melatonin sensitizes leukemia cells to the MCL1 inhibitors S63845 and A‐1210477 through multiple pathways	17
Pan‐cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer	17
Thirty‐seven years of MT1 and MT2 melatonin receptor localization in the brain: Past and future challenges	17
Melatonin, an Antitumor Necrosis Factor Therapy	17
Measuring morning melatonin levels with plasma melatonin ELISA kits is a poor choice on two levels	16
Melatonin and Exercise Restore Myogenesis and Mitochondrial Dynamics Deficits Associated With Sarcopenia in iMS‐Bmal1−/− Mice	15
Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho‐1/Gpx4 pathway to prevent α‐synuclein‐induced ferroptosis in Parkinson's disease	15
Therapeutic potential of melatonin and melatonergic drugs on K18‐hACE2 mice infected with SARS‐CoV‐2	15
Melatonin protects against developmental PBDE‐47 neurotoxicity by targeting the AMPK/mitophagy axis	15
High sensitivity of melatonin suppression response to evening light in preschool‐aged children	14
Cyclic uniaxial mechanical load enhances chondrogenesis through entraining the molecular circadian clock	14
Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs	14
Hypnotic effects of melatonin depend on the environmental lighting conditions in the rat	13
Impact of endogenous melatonin on rhythmic behaviors, reproduction, and survival revealed in melatonin‐proficient C57BL/6J congenic mice	13

RETRACTION: Melatonin Inhibits Autophagy and Endoplasmic Reticulum Stress in Mice With Carbon Tetrachloride‐Induced Fibrosis	13
Melatonin Regulates Rheumatoid Synovial Fibroblasts‐Related Inflammation: Implications for Pathological Skeletal Muscle Treatment	13
Zebrafish Dark‐Dependent Behavior Requires Phototransduction by the Pineal Gland	13
Safety of higher doses of melatonin in adults: A systematic review and meta‐analysis	13
Melatonin Regulates Neuronal Synaptic Plasticity in the Supramammillary Nucleus and Attenuates Methamphetamine‐Induced Conditioned Place Preference and Sensitization in Mice	13
Greater sensitivity of the circadian system of women to bright light, but not dim‐to‐moderate light	13
Weekly and seasonal variation in the circadian melatonin rhythm in humans: A response	13
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Retraction Statement: Actions of melatonin mixed with collagenized porcine bone versus porcine bone only on osteointegration of dental implants	12
Weekly and seasonal variation in the circadian melatonin rhythm in humans: Entrained to local clock time, social time, light exposure or sun time?	11
Histone deacetylase 9 regulates disease resistance through fine‐tuning histone deacetylation of melatonin biosynthetic genes and melatonin accumulation in cassava	11
Criticism on the Incorrect Use of Oxygen–Ozone Therapy in Medicine	11
Melatonin reduces brain injury following inflammation‐amplified hypoxia–ischemia in a translational newborn piglet study of neonatal encephalopathy	11
Cross‐species single‐cell landscape of vertebrate pineal gland	11
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Melatonin rescues the mitochondrial function of bone marrow‐derived mesenchymal stem cells and improves the repair of osteoporotic bone defect in ovariectomized rats	10
Melatonin receptor structure and signaling	10
Quality‐of‐life outcomes following topical melatonin application against acute radiation dermatitis in patients with early breast cancer: A double‐blind, randomized, placebo‐controlled trial	10
Melatonin and Seasonal Synchrony in Mammals	10
Melatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views	10
KARS Mutations Impair Brain Myelination by Inducing Oligodendrocyte Deficiency: One Potential Mechanism and Improvement by Melatonin	10
Melatonin functions as a broad‐spectrum antifungal by targeting a conserved pathogen protein kinase	10
Melatonin alleviates myocardial dysfunction through inhibition of endothelial‐to‐mesenchymal transition via the NF‐κB pathway	9
Dose assessment of melatonin in sepsis (DAMSEL2) study: Pharmacokinetics of two doses of oral melatonin in patients with sepsis	9
Melatonin‐mediated malic enzyme 2 orchestrates mitochondrial fusion and respiratory functions to promote odontoblastic differentiation during tooth development	9
Correction to “Effects of melatonin on fatty liver disease: The role of NR4A1/DNA‐PKcs/p53 pathway, mitochondrial fission, and mitophagy”	9
Melatonin synthesis genes N‐acetylserotonin methyltransferases evolved into caffeic acid O‐methyltransferases and both assisted in plant terrestrialization	9
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OPA1 Mediated Fatty Acid β‐Oxidation in Hepatocyte: The Novel Insight for Melatonin Attenuated Apoptosis in Concanavalin A Induced Acute Liver Injury	9
RETRACTION: Melatonin Induces Cell Cycle Arrest and Apoptosis in Hepatocarcinoma HepG2 Cell Line	8
Exogenous melatonin decreases circadian misalignment and body weight among early types	8
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Melatonin facts: Lack of evidence that melatonin is a radical scavenger in living systems	8
Identification of Predictors of Shift Work Adaptation and Its Association With Immune, Hormonal and Metabolite Biomarkers	8
S‐cone contribution to the acute melatonin suppression response in humans	8
Identification of a COMT Gene Involved in the Biosynthesis of Melatonin Which Mediates Resistance to Citrus Canker	8
Evening chronotype is associated with hormonal and metabolic disorders in polycystic ovary syndrome	8
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RETRACTION: Melatonin Modulates Dysregulated Circadian Clocks in Mice With Diethylnitrosamine‐Induced Hepatocellular Carcinoma	8
Protective Activity of Melatonin Combinations and Melatonin‐Based Hybrid Molecules in Neurodegenerative Diseases	8
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Biosynthesis of neuroprotective melatonin is dysregulated in Huntington's disease	7
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Melatonin Protects Against Colistin‐Induced Intestinal Inflammation and Microbiota Dysbiosis	7
Delayed circadian rhythms in older Africans living with human immunodeficiency virus (HIV)	7
Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR‐135b‐3p/TOX3 axis	7
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Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification	7
Corrigendum to “melatonin ameliorates PM2.5‐induced cardiac perivascular fibrosis through regulating mitochondrial redox homeostasis”	7
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Correction to “PP2C1 Fine‐Tunes Melatonin Biosynthesis and Phytomelatonin Receptor PMTR1 Binding to Melatonin in Cassava”	7
Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner	6
Melatonin inhibits lung cancer development by reversing the Warburg effect via stimulating the SIRT3/PDH axis	6
Design, Synthesis, and Antifungal Activity of Melatonin Derivatives Containing a (Thio)Semicarbazide Group	6
Mechanism of Exogenous Melatonin to Alleviate the Fermentation Performance of Saccharomyces cerevisiae Under Copper Stress	6
Clock‐controlled arylalkylamine N‐acetyltransferase (aaNAT) regulates circadian rhythms of locomotor activity in the American cockroach, Periplaneta americana, via melatonin/MT2‐l	6
Ramelteon for delirium prevention in hospitalized patients: An updated meta‐analysis and trial sequential analysis of randomized controlled trials	6
RETRACTION: Melatonin Inhibits the Sphingosine Kinase 1/Sphingosine‐1‐Phosphate Signaling Pathway in Rabbits With Fulminant Hepatitis of Viral Origin	6
Melatonin improves cardiac remodeling and brain–heart sympathetic hyperactivation aggravated by light disruption after myocardial infarction	6
RP58 knockdown contributes to hypoxia‐ischemia‐induced pineal dysfunction and circadian rhythm disruption in neonatal rats	6
Novel melatonin‐producing Bacillus safensis EH143 mitigates salt and cadmium stress in soybean	6
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors	6
Meditation Linked to Enhanced MRI Signal Intensity in the Pineal Gland and Reduced Predicted Brain Age	6
In vitro deacetylation of N‐acetylserotonin by arylacetamide deacetylase	5
Retraction Statement: Melatonin plus porcine bone on discrete calcium deposit implant surface stimulates osteointegration in dental implants	5
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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport	5
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Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy	5
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The ISL LIM‐homeobox 2 transcription factor is negatively regulated by circadian adrenergic signaling to repress the expression of Aanat in pinealocytes of the rat pineal gland	4
In‐person vs home schooling during the COVID‐19 pandemic: Differences in sleep, circadian timing, and mood in early adolescence	4

Melatonin Repairs the Lipidome of Human Hepatocytes Exposed to Cd and Free Fatty Acid‐Induced Lipotoxicity	4
Melatonin alleviates PM2.5‐induced glucose metabolism disorder and lipidome alteration by regulating endoplasmic reticulum stress	4
Relationship Between Melatonin Receptor Agonists and Parkinson's Disease	4
Melatonin Prevents Thioacetamide–Induced Gut Leakiness and Liver Fibrosis Through the Gut–Liver Axis via Modulating Sirt1‐Related Deacetylation of Gut Junctional Complex and Hepatic Proteins	4
RETRACTION: Melatonin Prevents Deregulation of the Sphingosine Kinase/Sphingosine 1‐Phosphate Signaling Pathway in a Mouse Model of Diethylnitrosamine‐Induced Hepatocellular Carcinoma	4
Rational modification of melatonin for broad‐spectrum antifungal agents discovery	4
Recharge of chondrocyte mitochondria by sustained release of melatonin protects cartilage matrix homeostasis in osteoarthritis	4
RETRACTION: Melatonin Attenuates Apoptotic Liver Damage in Fulminant Hepatic Failure Induced by the Rabbit Hemorrhagic Disease Virus	3
N1‐Acetyl‐5‐methoxykynuramine, which decreases in the hippocampus with aging, improves long‐term memory via CaMKII/CREB phosphorylation	3
Melatonin suppresses the metastatic potential of osteoblastic prostate cancers by inhibiting integrin α2β1 expression	3
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Adrenergic Agonists Activate Transcriptional Activity in Immortalized Neuronal Cells From the Mouse Suprachiasmatic Nucleus	3
The potential remedy of melatonin on osteoarthritis	3
Resetting of the Human Circadian Melatonin Rhythm by Ambient Hypoxia	3
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Safety and efficacy of melatonin supplementation as an add‐on treatment for infantile epileptic spasms syndrome: A randomized, placebo‐controlled, double‐blind trial	3
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GATA3‐COMT1‐Melatonin as Upstream Signaling of ABA Participated in Se‐Enhanced Cold Tolerance by Regulate Iron Uptake and Distribution in Cucumis sativus L	2
iMS‐Bmal1−/− mice show evident signs of sarcopenia that are counteracted by exercise and melatonin therapies	2
Melatonin and aggressive behavior: A systematic review of the literature on preclinical and clinical evidence	2
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Treatment of isolated REM sleep behavior disorder using melatonin as a chronobiotic	2
Healthy Lifestyles Modify the Association of Melatonin Receptor 1B Gene and Ischemic Stroke: A Family‐Based Cohort Study in Northern China	2
Orchestrated feedback regulation between melatonin and sex hormones involving GPER1‐PKA‐CREB signaling in the placenta	2
RETRACTION: Regulation of Prostaglandin Production in Carrageenan‐Induced Pleurisy Melatonin	2
Journal of Pineal Research guidelines for authors: Melatonin studies using plants	2
Ramelteon attenuates hippocampal neuronal loss and memory impairment following kainate‐induced seizures	2
Melatonin suppression by light involves different retinal photoreceptors in young and older adults	2
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Role and neural regulation of clock genes in the rat pineal gland: Clock modulates amplitude of rhythmic expression of Aanat encoding the melatonin‐producing enzyme	2
Shift and longtime light induces endometrioid adenocarcinoma via activation of PKC‐α/Akt pathway in female golden hamster: Involvement of altered Aanat and Bmal1 rhythm	2
Genetic and evolutionary dissection of melatonin response signaling facilitates the regulation of plant growth and stress responses	2
Industrial and academic approaches to the search for alternative melatonin receptor ligands: An historical survey	2
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