Journal of Pineal Research

Article	Citations
Transcriptomic and Metabolomic Signatures of Acute Circadian Misalignment in Mice	132
RETRACTION: Changes in the Expression of Melatonin Receptors Induced by Melatonin Treatment in Hepatocarcinoma HepG2 Cells	93
Correction to high sensitivity of melatonin suppression response to evening light in preschool‐aged children	70
Zygotic Exposure to Venlafaxine Disrupts the Circadian Locomotor Activity Behaviour in Zebrafish Larvae	68
Melatonin Increased Autophagy Level to Facilitate Osteogenesis of Inflamed PDLSCs Through TMEM110 Signaling Pathways	57
Melatonin mediates reactive oxygen species homeostasis via SlCV to regulate leaf senescence in tomato plants	53
BPS‐induced ovarian dysfunction: Protective actions of melatonin via modulation of SIRT‐1/Nrf2/NFĸB and IR/PI3K/pAkt/GLUT‐4 expressions in adult golden hamster	52
Microbial Melatonin Production Improves Plant Metabolic Function in Short‐Term Climate‐Induced Stresses	50
Melatonin as a chronobiotic/cytoprotective agent in bone. Doses involved	48
Melatonin targets MoIcl1 and works synergistically with fungicide isoprothiolane in rice blast control	48
A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensi	47
Melatonin inhibits chondrosarcoma cell proliferation and metastasis by enhancing miR‐520f‐3p production and suppressing MMP7 expression	46
Erratum to: Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin‐induced apoptosis in neural cancer cells	43
From Seasonality to Species Conservation: Chronobiological Research on European Hamsters in Strasbourg, France	43
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Investigating the safety profiles of exogenous melatonin and associated adverse events: A pharmacovigilance study using WHO‐VigiBase	39
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Exogenous Melatonin Regulates Hormone Signalling and Photosynthesis‐Related Genes to Enhance Brassica napus. Yield: A Transcriptomic Perspective	38
Light‐Dependent Circadian Rhythm Governs O‐GlcNAc Cycling to Influence Cognitive Function in Adult Zebrafish	36
Optimizing the Time and Dose of Melatonin as a Sleep‐Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose−Response Meta‐Analysis	34
Melatonin Ameliorates Atherosclerotic Plaque Vulnerability by Regulating PPARδ‐Associated Smooth Muscle Cell Phenotypic Switching	34
Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model	34
RETRACTION: Melatonin Inhibits the Expression of the Inducible Isoform of Nitric Oxide Synthase and Nuclear Factor Kappa B Activation in Rat Skeletal Muscle	33
Correction to “Melatonin mediates selenium‐induced tolerance to cadmium stress in tomato plants”	33

No association between a common type 2 diabetes risk gene variant in the melatonin receptor gene (MTNR1B) and mortality among type 2 diabetes patients	32
Melatonin treatment improves ventricular conduction via upregulation of Nav1.5 channel proteins and sodium current in the normal rat heart	31
Light Environment of Arctic Solstices is Coupled With Melatonin Phase‐Amplitude Changes and Decline of Metabolic Health	31
Predicting melatonin suppression by light in humans: Unifying photoreceptor‐based equivalent daylight illuminances, spectral composition, timing and duration of light exposure	30
Melatonin improves skin barrier damage caused by sleep restriction through gut microbiota	30
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Melatonin prevents EAAC1 deletion‐induced retinal ganglion cell degeneration by inhibiting apoptosis and senescence	28
Relationship Between Urinary 6‐Sulfatoxymelatonin Rhythms and the Bone Resorption Marker Amino‐Terminal Cross‐Linked Telopeptide of Collagen I in Blind Women	27
Effect of melatonin on ATG2B‐mediated autophagy regulation in sheep granulosa cells with different FecB genotypes	26
3‐Month Melatonin Supplementation to Reduce Brain Oxidative Stress and Improve Sleep in Mild Cognitive Impairment: A Randomised Controlled Feasibility Trial	26
From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin	26
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Effect of melatonin cream on acute radiation dermatitis in patients with primary breast cancer: A double‐blind, randomized, placebo‐controlled trial	26
Melatonin Rescues Influenza A Virus–Induced Cellular Energy Exhaustion via OMA1‐OPA1‐S in Acute Exacerbation of COPD	25
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EXPRESSION OF CONCERN: Mitochondrial Function Is Controlled by Melatonin and Its Metabolites In Vitro in Human Melanoma Cells	24
Melatonin Ameliorates Circadian Disruption‐Associated Dry Eye via Modulation of BMAL1‐REV‐ERBα‐IL‐17 Axis and Ocular Surface Microbiota Homeostasis	24
Homeobox gene‐encoded transcription factors in development and mature circadian function of the rodent pineal gland	22
In Vitro and In Vivo Effects of Melatonin‐Containing Combinations in Human Pancreatic Ductal Adenocarcinoma	22
Orphan GPR50 Restrains Neurite Outgrowth and Cell Migration by Activating the G12/13 Protein‐RhoA Pathway in Neural Progenitor Cells and Tanycytes	22
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics	22
Multi‐Omics Analysis Reveals That AhNHL Contributes to Melatonin‐Mediated Cadmium Tolerance in Peanut Plants	21
Single‐cell transcriptomic analysis reveals circadian rhythm disruption associated with poor prognosis and drug‐resistance in lung adenocarcinoma	21
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Melatonin Affects Peucedanum praeruptorum Vegetative Growth and Coumarin Synthesis by Modulating the Antioxidant System, Photosynthesis, and Endogenous Hormones	20
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Melatonin as a key regulator in seed germination under abiotic stress	20
NPAS2 Deficiency Leads to Antidepressant‐Like Behaviors in Mice by Modulating Astrocyte‐Mediated Neuroinflammation	20
Protective Effects of Melatonin on Kidney Function Against Contrast Media‐Induced Kidney Damage in Patients With Chronic Kidney Disease: A Prospective, Randomized, Double‐Blinded, Placebo‐Controlled T	20
Relating Photoperiod and Outdoor Temperature With Sleep Architecture in Patients With Neuropsychiatric Sleep Disorders	20
Mouse Models in Circadian Rhythm and Melatonin Research	20
Melatonin Alleviates Osteoarthritis by Regulating NADPH Oxidase 4–Induced Ferroptosis and Mitigating Mitochondrial Dysfunction	18
Melatonin Membrane Receptors in the Vascular System: Function, Modulation and Clinical Relevance	18
Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs	17
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Correction to “Melatonin/PGC1A/UCP1 promotes tumor slimming and represses tumor progression by initiating autophagy and lipid browning”	17
Melatonin Inhibits Endometriosis Growth via Specific Binding and Inhibition of EGFR Phosphorylation	17
Melatonin sensitizes leukemia cells to the MCL1 inhibitors S63845 and A‐1210477 through multiple pathways	17
Melatonin protects against developmental PBDE‐47 neurotoxicity by targeting the AMPK/mitophagy axis	16
The Mechanism by Which Melatonin Improves the Dysregulation of Glucose and Lipid Metabolism in Castrated Female Mice	16
Melatonin, an Antitumor Necrosis Factor Therapy	16
Cyclic uniaxial mechanical load enhances chondrogenesis through entraining the molecular circadian clock	16
Thirty‐seven years of MT1 and MT2 melatonin receptor localization in the brain: Past and future challenges	16
RETRACTION: Melatonin Inhibits Autophagy and Endoplasmic Reticulum Stress in Mice With Carbon Tetrachloride‐Induced Fibrosis	15
High sensitivity of melatonin suppression response to evening light in preschool‐aged children	15
Hypnotic effects of melatonin depend on the environmental lighting conditions in the rat	15
IAT4 , a New Indolamine N ‐Acetyltransferase in Saccharomyces cerevisiae Involv	15
Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho‐1/Gpx4 pathway to prevent α‐synuclein‐induced ferroptosis in Parkinson's disease	15
Melatonin and Exercise Restore Myogenesis and Mitochondrial Dynamics Deficits Associated With Sarcopenia in iMS‐ Bmal1 −/−	15
Zebrafish Dark‐Dependent Behavior Requires Phototransduction by the Pineal Gland	14

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Greater sensitivity of the circadian system of women to bright light, but not dim‐to‐moderate light	14
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Melatonin Regulates Rheumatoid Synovial Fibroblasts‐Related Inflammation: Implications for Pathological Skeletal Muscle Treatment	13
Safety of higher doses of melatonin in adults: A systematic review and meta‐analysis	13
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Histone deacetylase 9 regulates disease resistance through fine‐tuning histone deacetylation of melatonin biosynthetic genes and melatonin accumulation in cassava	13
Melatonin Supplementation Alleviates Bone Mineral Density Decline and Circulating Oxidative Stress in Iron‐Overloaded Thalassemia Patients	13
Melatonin Regulates Neuronal Synaptic Plasticity in the Supramammillary Nucleus and Attenuates Methamphetamine‐Induced Conditioned Place Preference and Sensitization in Mice	13
Quality‐of‐life outcomes following topical melatonin application against acute radiation dermatitis in patients with early breast cancer: A double‐blind, randomized, placebo‐controlled trial	12
Criticism on the Incorrect Use of Oxygen–Ozone Therapy in Medicine	12
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Cross‐species single‐cell landscape of vertebrate pineal gland	12
Melatonin reduces brain injury following inflammation‐amplified hypoxia–ischemia in a translational newborn piglet study of neonatal encephalopathy	12
KARS Mutations Impair Brain Myelination by Inducing Oligodendrocyte Deficiency: One Potential Mechanism and Improvement by Melatonin	12
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Melatonin and Seasonal Synchrony in Mammals	11
Melatonin rescues the mitochondrial function of bone marrow‐derived mesenchymal stem cells and improves the repair of osteoporotic bone defect in ovariectomized rats	11
Melatonin alleviates myocardial dysfunction through inhibition of endothelial‐to‐mesenchymal transition via the NF‐κB pathway	11
Melatonin‐mediated malic enzyme 2 orchestrates mitochondrial fusion and respiratory functions to promote odontoblastic differentiation during tooth development	11
Melatonin receptor structure and signaling	11
Standardized and Calibrated Light Stimuli via Head‐Mounted Displays for Investigating the Nonvisual Effects of Light	11
Correction to “Effects of melatonin on fatty liver disease: The role of NR4A1/DNA‐PKcs/p53 pathway, mitochondrial fission, and mitophagy”	11
Direct Peritoneal Resuscitation and Melatonin in the Treatment of Abdominal Sepsis‐Induced Lung Injury via Macrophage Metabolic Reprogramming	11
Melatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views	11
Melatonin functions as a broad‐spectrum antifungal by targeting a conserved pathogen protein kinase	11
Dose assessment of melatonin in sepsis (DAMSEL2) study: Pharmacokinetics of two doses of oral melatonin in patients with sepsis	10
Key Role of the CRE Sequence in the Per1 Promoter in Mediating the Switch Between Unipolar and Bipolar Depression‐Like Behaviors	10
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Coupling Melatonin and Ultrasound Modulates ROS Production, Antioxidant System, and Biochemical Attributes Linked to Oxidative Browning in Litchi Pericarp	10
OPA1 Mediated Fatty Acid β‐Oxidation in Hepatocyte: The Novel Insight for Melatonin Attenuated Apoptosis in Concanavalin A Induced Acute Liver Injury	10
Evening chronotype is associated with hormonal and metabolic disorders in polycystic ovary syndrome	9
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Melatonin Alleviates Oxidative Stress‐Induced Mitochondrial Dysfunction Through Ameliorating NAD + Homeostasis of hDPSCs for Cell‐Based Therapy	9
RETRACTION: Melatonin Modulates Dysregulated Circadian Clocks in Mice With Diethylnitrosamine‐Induced Hepatocellular Carcinoma	9
Melatonin facts: Lack of evidence that melatonin is a radical scavenger in living systems	9
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Melatonin Overcomes Cancer Multidrug Resistance by Downregulating ABCB1 Expression and Modulating Mitochondrial Function	9
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Biosynthesis of neuroprotective melatonin is dysregulated in Huntington's disease	8
Design, Synthesis, and Antifungal Activity of Melatonin Derivatives Containing a (Thio)Semicarbazide Group	8
Identification of a COMT Gene Involved in the Biosynthesis of Melatonin Which Mediates Resistance to Citrus Canker	8
Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR‐135b‐3p/TOX3 axis	8
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Melatonin improves cardiac remodeling and brain–heart sympathetic hyperactivation aggravated by light disruption after myocardial infarction	8
RETRACTION: Melatonin Induces Cell Cycle Arrest and Apoptosis in Hepatocarcinoma HepG2 Cell Line	8
Identification of Predictors of Shift Work Adaptation and Its Association With Immune, Hormonal and Metabolite Biomarkers	8
Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification	8
RETRACTION: Melatonin Inhibits the Sphingosine Kinase 1/Sphingosine‐1‐Phosphate Signaling Pathway in Rabbits With Fulminant Hepatitis of Viral Origin	8
Protective Activity of Melatonin Combinations and Melatonin‐Based Hybrid Molecules in Neurodegenerative Diseases	8
Meditation Linked to Enhanced MRI Signal Intensity in the Pineal Gland and Reduced Predicted Brain Age	7
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Melatonin Protects Against Colistin‐Induced Intestinal Inflammation and Microbiota Dysbiosis	7
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Ramelteon for delirium prevention in hospitalized patients: An updated meta‐analysis and trial sequential analysis of randomized controlled trials	7
RP58 knockdown contributes to hypoxia‐ischemia‐induced pineal dysfunction and circadian rhythm disruption in neonatal rats	7
Correction to “PP2C1 Fine‐Tunes Melatonin Biosynthesis and Phytomelatonin Receptor PMTR1 Binding to Melatonin in Cassava”	7
Corrigendum to “melatonin ameliorates PM2.5‐induced cardiac perivascular fibrosis through regulating mitochondrial redox homeostasis”	7
Mechanism of Exogenous Melatonin to Alleviate the Fermentation Performance of Saccharomyces cerevisiae Under Copper Stress	7
Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner	6
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Melatonin: A Potential Therapy for Osteoporosis With Insights Into Molecular Mechanisms	6
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors	6
Light and Temperature Coordinately Regulate Phytomelatonin Synthesis to Maintain Plant Morphogenesis via the COP1‐HY5 Module	6
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Delayed circadian rhythms in older Africans living with human immunodeficiency virus (HIV)	6
Novel melatonin‐producing Bacillus safensis EH143 mitigates salt and cadmium stress in soybean	6
Proteomic Signatures Underlying Sleep, Circadian Activity Patterns, and Major Chronic Diseases	6
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Functional Characterization of GNA1 as a Serotonin N ‐Acetyltransferase Reveals a Key Role in the Serotonin to Melatonin Pathway in <	5
Relationship Between Melatonin Receptor Agonists and Parkinson's Disease	5
RETRACTION: Melatonin Prevents Deregulation of the Sphingosine Kinase/Sphingosine 1‐Phosphate Signaling Pathway in a Mouse Model of Diethylnitrosamine‐Induced Hepatocellular Carcinoma	5
In vitro deacetylation of N‐acetylserotonin by arylacetamide deacetylase	5
Resetting of the Human Circadian Melatonin Rhythm by Ambient Hypoxia	5
The ISL LIM‐homeobox 2 transcription factor is negatively regulated by circadian adrenergic signaling to repress the expression of Aanat in pinealocytes of the rat pineal gland	5
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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport	5
Melatonin Prevents Thioacetamide–Induced Gut Leakiness and Liver Fibrosis Through the Gut–Liver Axis via Modulating Sirt1‐Related Deacetylation of Gut Junctional Complex and Hepatic Proteins	5
Recharge of chondrocyte mitochondria by sustained release of melatonin protects cartilage matrix homeostasis in osteoarthritis	5
Melatonin Enhances Aquaporin 4 and Alpha‐Syntrophin Interaction by Inhibiting Cyclin‐Dependent Kinase 5 Activity to Preserve Glymphatic Function in Neonatal Hypoxic‐Ischemic Encephalopathy	4
Melatonin alleviates PM2.5‐induced glucose metabolism disorder and lipidome alteration by regulating endoplasmic reticulum stress	4
RETRACTION: Melatonin Attenuates Apoptotic Liver Damage in Fulminant Hepatic Failure Induced by the Rabbit Hemorrhagic Disease Virus	4
Safety and efficacy of melatonin supplementation as an add‐on treatment for infantile epileptic spasms syndrome: A randomized, placebo‐controlled, double‐blind trial	4
Melatonin suppresses the metastatic potential of osteoblastic prostate cancers by inhibiting integrin α2β1 expression	4
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Melatonin Repairs the Lipidome of Human Hepatocytes Exposed to Cd and Free Fatty Acid‐Induced Lipotoxicity	4
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Adrenergic Agonists Activate Transcriptional Activity in Immortalized Neuronal Cells From the Mouse Suprachiasmatic Nucleus	4
Rational modification of melatonin for broad‐spectrum antifungal agents discovery	4
Exogenous Melatonin Enhances Waterlogging Tolerance in Sesame by Modulating Physiological, Biochemical, and Proteomic Responses	4
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Circadian Rhythm Timing and Associations With Sleep Symptoms in People With Insomnia	4
Shift and longtime light induces endometrioid adenocarcinoma via activation of PKC‐α/Akt pathway in female golden hamster: Involvement of altered Aanat and Bmal1 rhythm	3
RETRACTION: Regulation of Prostaglandin Production in Carrageenan‐Induced Pleurisy Melatonin	3
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Healthy Lifestyles Modify the Association of Melatonin Receptor 1B Gene and Ischemic Stroke: A Family‐Based Cohort Study in Northern China	3
Industrial and academic approaches to the search for alternative melatonin receptor ligands: An historical survey	3
Melatonin and aggressive behavior: A systematic review of the literature on preclinical and clinical evidence	3
Orchestrated feedback regulation between melatonin and sex hormones involving GPER1‐PKA‐CREB signaling in the placenta	3
N1‐Acetyl‐5‐methoxykynuramine, which decreases in the hippocampus with aging, improves long‐term memory via CaMKII/CREB phosphorylation	3
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Melatonin suppression by light involves different retinal photoreceptors in young and older adults	3
Correction to “Melatonin Inhibits Cd4+ T Cell Apoptosis via the Bcl‐2/BAX Pathway and Improves Survival Rates in Mice With Sepsis”	3
Journal of Pineal Research guidelines for authors: Melatonin studies using plants	3
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