OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Pineal Research is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
A phase II, single‐center, double‐blind, randomized placebo‐controlled trial to explore the efficacy and safety of intravenous melatonin in surgical patients with severe sepsis admitted to the intensi	98
Correction to high sensitivity of melatonin suppression response to evening light in preschool‐aged children	84
RETRACTION: Changes in the Expression of Melatonin Receptors Induced by Melatonin Treatment in Hepatocarcinoma HepG2 Cells	77
Zygotic Exposure to Venlafaxine Disrupts the Circadian Locomotor Activity Behaviour in Zebrafish Larvae	75
Corrigendum to Melatonin Attenuates D‐Galactose‐Induced Memory Impairment, Neuroinflammation and Neurodegeneration via Rage/Nf‐ _K B/Jnk Signaling Pat	73
Melatonin as a chronobiotic/cytoprotective agent in bone. Doses involved	62
Melatonin targets MoIcl1 and works synergistically with fungicide isoprothiolane in rice blast control	58
Therapeutic Potential of Melatonin in Gastrointestinal Cancers: Molecular Mechanisms, Preclinical Evidence and Clinical Implications	58
Microbial Melatonin Production Improves Plant Metabolic Function in Short‐Term Climate‐Induced Stresses	57
Melatonin Increased Autophagy Level to Facilitate Osteogenesis of Inflamed PDLSCs Through TMEM110 Signaling Pathways	52
Melatonin inhibits chondrosarcoma cell proliferation and metastasis by enhancing miR‐520f‐3p production and suppressing MMP7 expression	50
Transcriptomic and Metabolomic Signatures of Acute Circadian Misalignment in Mice	48
BPS‐induced ovarian dysfunction: Protective actions of melatonin via modulation of SIRT‐1/Nrf2/NFĸB and IR/PI3K/pAkt/GLUT‐4 expressions in adult golden hamster	45
From Seasonality to Species Conservation: Chronobiological Research on European Hamsters in Strasbourg, France	44
Issue Information	43
Melatonin Ameliorates Atherosclerotic Plaque Vulnerability by Regulating PPARδ‐Associated Smooth Muscle Cell Phenotypic Switching	42
Erratum to: Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin‐induced apoptosis in neural cancer cells	41
	41
Issue Information	40
Melatonin Enhances Peanut Productivity by Enriching Root‐Associated Nitrogen‐Fixing Bacteria	38
Light‐Dependent Circadian Rhythm Governs O‐GlcNAc Cycling to Influence Cognitive Function in Adult Zebrafish	36
Exogenous Melatonin Regulates Hormone Signalling and Photosynthesis‐Related Genes to Enhance Brassica napus. Yield: A Transcriptomic Perspective	36
EXPRESSION OF CONCERN: Melatonin Prevents Cadmium‐Induced Bone Damage: First Evidence on an Improved Osteogenic/Adipogenic Differentiation Balance of Mesenchymal Stem Cells as Underlying Mechanism	36
Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model	35
Investigating the safety profiles of exogenous melatonin and associated adverse events: A pharmacovigilance study using WHO‐VigiBase	34

Optimizing the Time and Dose of Melatonin as a Sleep‐Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose−Response Meta‐Analysis	33
From gestational chronodisruption to noncommunicable diseases: Pathophysiological mechanisms of programming of adult diseases, and the potential therapeutic role of melatonin	32
3‐Month Melatonin Supplementation to Reduce Brain Oxidative Stress and Improve Sleep in Mild Cognitive Impairment: A Randomised Controlled Feasibility Trial	32
	31
RETRACTION: Melatonin Suppresses Proinflammatory Mediators in Lipopolysaccharide‐Stimulated CRL1999 Cells via Targeting MAPK, NF‐κB, c/EBPβ, and p300 Signaling	31