OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Leukocyte Biology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Joost J. Oppenheim: 1934–2022	74
Phenotypes, roles, and modulation of regulatory lymphocytes in periodontitis and its associated systemic diseases	72
Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin	57
Sustained IL-4 priming of macrophages enhances the inflammatory response to TLR7/8 ligand R848	55
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Arhgef6 (alpha-PIX) cytoskeletal regulator signals to GTPases and Cofilin to couple T cell migration speed and persistence	36
Human macrophage polarization shapesB. pertussisintracellular persistence	36
Effects of TNF-α deletion on iNKT cell development, activation, and maturation in the steady-state and chronic alcohol-consuming mice	34
ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage	33
Relationship and prognostic significance of IL-33, PD-1/PD-L1, and tertiary lymphoid structures in cervical cancer	32
ERRγ, a new player in the type I IFN arena	32
Signaling networks in B cell development and related therapeutic strategies	32
TREM2splicing emerges as crucial aspect to understand TREM2 biology	30
Campylobacter jejuniinduces differentiation of human neutrophils to the CD16hi/CD62Llo subtype	30
Multifactorial assessment of neutrophil chemotaxis efficiency from a drop of blood	29
The lymphatic drainage system of the CNS plays a role in lymphatic drainage, immunity, and neuroinflammation in stroke	28
Immunotherapy targeting mesothelin in acute myeloid leukemia	27
Clinical utility of heparin-binding protein as an acute-phase inflammatory marker in interstitial lung disease	27
Polymorphonuclear myeloid-derived suppressor cells link inflammation and damage response after trauma	27
Scylla, Charybdis, and navigating antimicrobial action in the neutrophil phagosome	26
CTCF: A novel fusion partner of ETO2 in a multiple relapsed acute myeloid leukemia patient	26

Epigenetic regulation of T cells by Polycomb group proteins	25
Interference with long noncoding RNA SNHG3 alleviates cerebral ischemia-reperfusion injury by inhibiting microglial activation	24
Peony seed oil ameliorates neuroinflammation-mediated cognitive deficits by suppressing microglial activation through inhibition of NF-κB pathway in presenilin 1/2 conditional double knockout mice	24
Molecular and immune interactions between β- and γ-herpesviruses in the immunocompromised host	23
The FasLane to ocular pathology—metalloproteinase cleavage of membrane-bound FasL determines FasL function	22
Elevated F-EDN correlates with mucosal eosinophil degranulation in patients with IBS—A possible association with microbiota?	22
Neutrophil function and bactericidal activity againstStaphylococcus aureusafter cardiac surgery with cardiopulmonary bypass	21
Cross-reactive cellular, but not humoral, immunity is detected between OC43 and SARS-CoV-2 NPs in people not infected with SARS-CoV-2: Possible role of cTFH cells	21
Immunoregulation by type I interferons in the peritoneal cavity	21
Diabetes induces macrophage dysfunction through cytoplasmic dsDNA/AIM2 associated pyroptosis	21
TCF-1 maintains CD8+ T cell stemness in tumor microenvironment	20
Gut microbiota shape B cell in health and disease settings	20
Single-cell profiling of T lymphocytes in deficiency of adenosine deaminase 2	19
In vitro-induced Foxp3+CD8+ regulatory T cells suppress allergic IgE response in the gut	19
Pro-inflammatory polarization primes Macrophages to transition into a distinct M2-like phenotype in response to IL-4	19
DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signaling	19
HDAC11 regulates expression of C/EBPβ and immunosuppressive molecules in myeloid-derived suppressor cells	18
Clearance of HIV-1 or SIV reservoirs by promotion of apoptosis and inhibition of autophagy: Targeting intracellular molecules in cure-directed strategies	18
Kindlin-3 maintains marginal zone B cells but confines follicular B cell activation and differentiation	18
The Akt–mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferation	18
MiR-155 regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis	17
Neutrophil subsets and their differential roles in viral respiratory diseases	17
Circulating inflammatory cell profiling and periodontitis: A systematic review and meta-analysis	16
Analysis of potential biomarkers of response to IL-12 therapy	16
Current strategies to induce selective killing of HIV-1-infected cells	16
Platelet extracellular vesicles in COVID-19: Potential markers and makers	16
Use of integrated metabolomics, transcriptomics, and signal protein profile to characterize the effector function and associated metabotype of polarized macrophage phenotypes	16
Gender-dependent frequency of unconventional T cells in a healthy adult Caucasian population: A combinational study of invariant NKT cells, γδ T cells, and mucosa-associated invariant T cells	15
IL-38 prevents induction of trained immunity by inhibition of mTOR signaling	15
Neutrophil-derived extracellular vesicles promote feed-forward inflammasome signaling in cystic fibrosis airways	15
HMGB1: An overview of its roles in the pathogenesis of liver disease	15
Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells	15
Mechanism of chlorogenic acid in alveolar macrophage polarization in Klebsiella pneumoniae-induced pneumonia	15
Periodontal ligament stem cells in the periodontitis niche: inseparable interactions and mechanisms	15
Immunopathogenesis of oral submucous fibrosis by chewing the areca nut	14
Hemin-primed dendritic cells suppress allergic airway inflammation through releasing extracellular vesicles	14
Hemagglutinin-based DNA vaccines containing trimeric self-assembling nanoparticles confer protection against influenza	14
CAR NK-92 cells targeting DLL3 kill effectively small cell lung cancer cells in vitro and in vivo	14
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The prognostic value of a 4-factor neoimmunologic score system in non-small cell lung cancer	13
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The interaction between iNKT cells and B cells	12
Galectin-3 as a biomarker in breast neoplasms: Mechanisms and applications in patient care	12
Scientific premise for the involvement of neutrophil extracellular traps (NETs) in vaccine-induced thrombotic thrombocytopenia (VITT)	12
Tumor-intrinsic CD21 expression impacts the response of B-cell malignancy cells to CD19-CAR-T cells	12
PMN-MDSC in newborns: Regulation of the regulators	12
IL-7 induces type 2 cytokine response in lung ILC2s and regulates GATA3 and CD25 expression	12

SUZ12 participates in the proliferation of PNH clones by regulating histone H3K27me3 levels	12
IL-1β/NF-κB signaling inhibits IGF-1 production via let-7f-5p in dendritic epidermal T cells	12
STAT5 promotes chronic pancreatitis by enhancing GM-CSF-dependent neutrophil augmentation	12
Identification of altered cell signaling pathways using proteomic profiling in stable and progressive chronic lymphocytic leukemia	12
Neutrophil serine proteases in vitro: How much and why?	12
Issue Information	12
Helminth infections and cardiovascular diseases: A role for the microbiota and Mϕs?	12
Follicular regulatory T cell biology and its role in immune-mediated diseases	11
T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death	11
Dynamic immune ecosystem of dengue infection revealed by single-cell sequencing	11
IL-17A aggravates asthma-induced intestinal immune injury by promoting neutrophil trafficking	11
The microbiota-gut-bone axis and bone health	11
Gift bags from the sentinel cells of the immune system: The diverse role of dendritic cell-derived extracellular vesicles	11
TRB sequences targeting ORF1a/b are associated with disease severity in hospitalized COVID-19 patients	11
Single-cell immune profiling reveals long-term changes in myeloid cells and identifies a novel subset of CD9+ monocytes associated with COVID-19 hospitalization	11
Lymphocytes sense antibodies through human FCRL proteins: Emerging roles in mucosal immunity	11
Loss of mitochondrial membrane potential (ΔΨm) in leucocytes as post-COVID-19 sequelae	10
Novel neutrophil phenotypic signature in pediatric patients with type 1 diabetes and diabetic ketoacidosis	10
A review of the mechanisms of keratinocytes damage caused byStaphylococcus aureusinfection in patients with atopic dermatitis	10
The role of naturally acquired antimalarial antibodies in subclinicalPlasmodiumspp. infection	10
Differential expression of maturation and activation markers on NK cells in patients with active and latent tuberculosis	10
BRAF-V600E utilizes posttranscriptional mechanisms to amplify LPS-induced TNFα production in dendritic cells in a mouse model of Langerhans cell histiocytosis	10
Stabilizing the immune system by chlorogenic acid	10
Acute lymphoblastic leukemia-secreted miRNAs induce a proinflammatory microenvironment and promote the activation of hematopoietic progenitors	10
Aging and macrophages: Not standing the test of time?	10
Management of systemic risk factors ahead of dental implant therapy: A beard well lathered is half shaved	10
Intrathymic SIRPa cDC subsets organization in normal and stress conditions reveal another level of cDCs heterogeneity	10
Inflammasome regulation in driving COVID-19 severity in humans and immune tolerance in bats	10
CCAAT/enhancer binding protein (C/EBP) delta promotes the expression of PTX3 and macrophage phagocytosis duringA. fumigatusinfection	10
BCG-trained innate immunity leads to fetal growth restriction by altering immune cell profile in the mouse developing placenta	10
HIV-1-induced type I IFNs promote viral latency in macrophages	10
More than neutrophils: Lin(+)Ly6G(+)IL-5Rα(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes	10
Mitofusin-2 regulates leukocyte adhesion and β2 integrin activation	10