OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Leukocyte Biology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The vitals of NETs	101
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19	82
IFNγ-mediated repression of system xc− drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells	72
Neutrophils mediate Th17 promotion in COVID-19 patients	69
The microbiota-gut-bone axis and bone health	66
Leptin correlates with monocytes activation and severe condition in COVID-19 patients	61
Cellular immune responses in the pathophysiology of preeclampsia	57
Alveolar and lung interstitial macrophages: Definitions, functions, and roles in lung fibrosis	56
Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells	51
B cell analysis in SARS-CoV-2 versus malaria: Increased frequencies of plasmablasts and atypical memory B cells in COVID-19	47
Sustained calcium ion release from bioceramics promotes CaSR-mediated M2 macrophage polarization for osteoinduction	45
Identification of key signaling pathways induced by SARS-CoV2 that underlie thrombosis and vascular injury in COVID-19 patients	41
Intersection between macrophages and periodontal pathogens in periodontitis	40
Direct and indirect regulation of the tumor immune microenvironment by VEGF	40
Role of IL-6 in dendritic cell functions	39
Porphyromonas gingivalisinduces periodontitis, causes immune imbalance, and promotes rheumatoid arthritis	36
Dynamic changes in human single-cell transcriptional signatures during fatal sepsis	36
Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin	33
Periodontal ligament stem cells in the periodontitis niche: inseparable interactions and mechanisms	32
ADAM17/MMP inhibition prevents neutrophilia and lung injury in a mouse model of COVID-19	32
Use of integrated metabolomics, transcriptomics, and signal protein profile to characterize the effector function and associated metabotype of polarized macrophage phenotypes	32
Loss of mitochondrial membrane potential (ΔΨm) in leucocytes as post-COVID-19 sequelae	32
CAR NK-92 cells targeting DLL3 kill effectively small cell lung cancer cells in vitro and in vivo	31
IL-34 and CSF-1, deciphering similarities and differences at steady state and in diseases	29
Follicular helper T cells and follicular regulatory T cells in the immunopathology of primary Sjögren’s syndrome	29

Periodontal ligament stem cells promote polarization of M2 macrophages	29
Platelet extracellular vesicles in COVID-19: Potential markers and makers	27
HMGB1: An overview of its roles in the pathogenesis of liver disease	27
T follicular helper cells in the humoral immune response to SARS-CoV-2 infection and vaccination	27
Differential expression and regulation of MS4A family members in myeloid cells in physiological and pathological conditions	26
Macrophage M1/M2 polarization dynamically adapts to changes in microenvironment and modulates alveolar bone remodeling after dental implantation	26
The spleen: “epicenter” in malaria infection and immunity	26
Emergence of immunosuppressive LOX-1+ PMN-MDSC in septic shock and severe COVID-19 patients with acute respiratory distress syndrome	26
Pro-inflammatory polarization primes Macrophages to transition into a distinct M2-like phenotype in response to IL-4	25
FOXO3a acetylation regulates PINK1, mitophagy, inflammasome activation in murine palmitate-conditioned and diabetic macrophages	24
T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death	24
Extracellular vesicles in inflammation: Focus on the microRNA cargo of EVs in modulation of liver diseases	23
Melanoma-derived extracellular vesicles skew neutrophils into a pro-tumor phenotype	22
Analysis of deficiency of adenosine deaminase 2 pathogenesis based on single-cell RNA sequencing of monocytes	21
IL-38 prevents induction of trained immunity by inhibition of mTOR signaling	21
Role of extracellular vesicles in atherosclerosis: An update	21
MiR-155 regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis	21
Stem cell-like memory T cells: The generation and application	21
Synthesis and identification of lithocholic acid 3-sulfate as RORγt ligand to inhibit Th17 cell differentiation	20
Novel TREM2 splicing isoform that lacks the V-set immunoglobulin domain is abundant in the human brain	20
Anticancer effects of disulfiram in T-cell malignancies through NPL4-mediated ubiquitin–proteasome pathway	19
Role of vitamin D in regulating COVID-19 severity—An immunological perspective	19
TCF-1 maintains CD8+ T cell stemness in tumor microenvironment	19
LncRNA SNHG12 alleviates hypertensive vascular endothelial injury through miR-25-3p/SIRT6 pathway	19
The imbalance of Th17/Treg via STAT3 activation modulates cognitive impairment inP. gingivalis LPS-induced periodontitis mice	19
Plasma extracellular vesicles released after severe burn injury modulate macrophage phenotype and function	19
Flow cytometric evaluation of the neutrophil compartment in COVID-19 at hospital presentation: A normal response to an abnormal situation	19
The lymphatic drainage system of the CNS plays a role in lymphatic drainage, immunity, and neuroinflammation in stroke	19
Immunomodulatory functions of oral mesenchymal stem cells: Novel force for tissue regeneration and disease therapy	18
VIP plasma levels associate with survival in severe COVID-19 patients, correlating with protective effects in SARS-CoV-2-infected cells	18
Scientific premise for the involvement of neutrophil extracellular traps (NETs) in vaccine-induced thrombotic thrombocytopenia (VITT)	18
Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells	18
The regulatory role of insulin in energy metabolism and leukocyte functions	17
Diabetes induces macrophage dysfunction through cytoplasmic dsDNA/AIM2 associated pyroptosis	17
Sepsis, pyruvate, and mitochondria energy supply chain shortage	16
Circulating inflammatory cell profiling and periodontitis: A systematic review and meta-analysis	16
Sinomenine increases adenosine A2A receptor and inhibits NF-κB to inhibit arthritis in adjuvant-induced-arthritis rats and fibroblast-like synoviocytes through α7nAChR	16
Characterization of memory T cell subsets and common γ−chain cytokines in convalescent COVID-19 individuals	16
Immunopathogenesis of oral submucous fibrosis by chewing the areca nut	16
Insulin acutely activates metabolism of primary human monocytes and promotes a proinflammatory phenotype	15
Neutrophil-derived extracellular vesicles promote feed-forward inflammasome signaling in cystic fibrosis airways	15
In silico design of a TLR4-mediating multiepitope chimeric vaccine against amyotrophic lateral sclerosis via advanced immunoinformatics	15
LncRNA SNHG8 sponges miR-449c-5p and regulates the SIRT1/FoxO1 pathway to affect microglia activation and blood-brain barrier permeability in ischemic stroke	15
Gut microbiota shape B cell in health and disease settings	15
Neuroimmune regulatory networks of the airway mucosa in allergic inflammatory disease	15
Immune modulatory effects of progesterone on oxLDL-induced trained immunity in monocytes	15
Effects of mesenchymal stromal cell-derived extracellular vesicles in acute respiratory distress syndrome (ARDS): Current understanding and future perspectives	14
Immunopathology of chronic critical illness in sepsis survivors: Role of abnormal myelopoiesis	14
GABAergic signaling in human and murine NK cells upon challenge withToxoplasma gondii	14
The role of bacterial DNA containing CpG motifs in diseases	13

IL-26 promotes the pathogenesis of malignant pleural effusion by enhancing CD4+IL-22+ T-cell differentiation and inhibiting CD8+ T-cell cytotoxicity	13
K27-linked noncanonic ubiquitination in immune regulation	13
Interference with long noncoding RNA SNHG3 alleviates cerebral ischemia-reperfusion injury by inhibiting microglial activation	13
A novel strategy to dissect multifaceted macrophage function in human diseases	13
Iron deprivation restrains the differentiation and pathogenicity of T helper 17 cell	13
Lymphocytes sense antibodies through human FCRL proteins: Emerging roles in mucosal immunity	13
P2Y12 antagonism results in altered interactions between platelets and regulatory T cells during sepsis	13
Monocytic myeloid-derived suppressor cells reflect tuberculosis severity and are influenced by cyclooxygenase-2 inhibitors	13
Neutrophil subsets and their differential roles in viral respiratory diseases	13
The histone deacetylase Hdac7 supports LPS-inducible glycolysis and Il-1β production in murine macrophages via distinct mechanisms	12
PRDM1 decreases sensitivity of human NK cells to IL2-induced cell expansion by directly repressing CD25 (IL2RA)	12
The effect of an isoquinoline alkaloid on treatment of periodontitis by regulating the neutrophils chemotaxis	12
Mechanisms of HIV-1 cell-to-cell transfer to myeloid cells	12
Inflammasome regulation in driving COVID-19 severity in humans and immune tolerance in bats	12
γδ T cell exhaustion: Opportunities for intervention	12
Modulation of surface CD11c expression tracks plasticity in murine intestinal tissue eosinophils	12
Animal models for studies of HIV-1 brain reservoirs	12
Blood tests predict the therapeutic prognosis of anti-PD-1 in advanced biliary tract cancer	12
Stem cells from exfoliated deciduous teeth transplantation ameliorates Sjögren's syndrome by secreting soluble PD-L1	12
Single-cell profiling of T lymphocytes in deficiency of adenosine deaminase 2	12
Sodium houttuyfonate attenuates dextran sulfate sodium associated colitis precolonized withCandida albicansthrough inducing β-glucan exposure	12
Neutrophil-derived extracellular vesicles modulate the phenotype of naïve human neutrophils	11
Annexin A2 regulates unfolded protein response via IRE1–XBP1 axis in macrophages duringP. aeruginosainfection	11
Shock and kill within the CNS: A promising HIV eradication approach?	11
MDS-associated SF3B1 mutations enhance proinflammatory gene expression in patient blast cells	11
Serum sphingolipid profile in asthma	11
IL-17A produced by invariant natural killer T cells and CD3+CD56+αGalcer-CD1d tetramer– T cells promote liver fibrosis in patients with primary biliary cholangitis	11
Bone marrow microenvironment drives AML cell OXPHOS addiction and AMPK inhibition to resist chemotherapy	11
Mechanism of chlorogenic acid in alveolar macrophage polarization in Klebsiella pneumoniae-induced pneumonia	11
Tissue-specific murine neutrophil activation states in health and inflammation	11
Microglial activation in Alzheimer's disease: The role of flavonoids and microRNAs	11
HIV-1-induced type I IFNs promote viral latency in macrophages	11
Relationship and prognostic significance of IL-33, PD-1/PD-L1, and tertiary lymphoid structures in cervical cancer	11