Journal of Leukocyte Biology

Papers
(The median citation count of Journal of Leukocyte Biology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)
ArticleCitations
Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and therapy concepts551
Frontline Science: COVID-19 infection induces readily detectable morphologic and inflammation-related phenotypic changes in peripheral blood monocytes173
NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma126
Natural products and their derivatives: Promising modulators of tumor immunotherapy123
Innate immune receptors in platelets and platelet-leukocyte interactions98
Neutrophil calprotectin identifies severe pulmonary disease in COVID-1992
Multiple roles of caspase-8 in cell death, inflammation, and innate immunity86
The vitals of NETs85
Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex83
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-1978
Neutrophils mediate Th17 promotion in COVID-19 patients66
Increasing complexity of NLRP3 inflammasome regulation63
IFNγ-mediated repression of system xc− drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells60
The microbiota-gut-bone axis and bone health59
Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions58
Specialized immune responses in the peritoneal cavity and omentum58
Leptin correlates with monocytes activation and severe condition in COVID-19 patients58
The role of the microbiome and the NLRP3 inflammasome in the gut and lung55
Surmounting the obstacles that impede effective CAR T cell trafficking to solid tumors51
Cellular immune responses in the pathophysiology of preeclampsia50
Alveolar and lung interstitial macrophages: Definitions, functions, and roles in lung fibrosis46
B cell analysis in SARS-CoV-2 versus malaria: Increased frequencies of plasmablasts and atypical memory B cells in COVID-1943
Roles of IL-2 in bridging adaptive and innate immunity, and as a tool for cellular immunotherapy41
Notch signaling at the crossroads of innate and adaptive immunity41
The neuro-immune microenvironment of acupoints—initiation of acupuncture effectiveness39
Sustained calcium ion release from bioceramics promotes CaSR-mediated M2 macrophage polarization for osteoinduction39
Identification of key signaling pathways induced by SARS-CoV2 that underlie thrombosis and vascular injury in COVID-19 patients38
Molecular interactions and functions of IL-3237
Intestinal intraepithelial lymphocytes: Maintainers of intestinal immune tolerance and regulators of intestinal immunity37
Age-related changes in intestinal immunity and the microbiome37
Direct and indirect regulation of the tumor immune microenvironment by VEGF35
Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells34
Porphyromonas gingivalisinduces periodontitis, causes immune imbalance, and promotes rheumatoid arthritis34
Intersection between macrophages and periodontal pathogens in periodontitis34
Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions33
From virus to inflammation, how influenza promotes lung damage33
Unraveling exhaustion in adaptive and conventional NK cells32
Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin31
ADAM17/MMP inhibition prevents neutrophilia and lung injury in a mouse model of COVID-1931
Role of IL-6 in dendritic cell functions30
Dynamic changes in human single-cell transcriptional signatures during fatal sepsis30
Regulatory functions of NK cells during infections and cancer29
RAC2 and primary human immune deficiencies29
At the Bench: Pre-clinical evidence for multiple functions of CXCR4 in cancer28
Loss of mitochondrial membrane potential (ΔΨm) in leucocytes as post-COVID-19 sequelae27
Changing the paradigm of IFN-γ at the interface between innate and adaptive immunity: Macrophage-derived IFN-γ27
Drug target validation in primary human natural killer cells using CRISPR RNP27
Spinal microglia-neuron interactions in chronic pain27
T regulatory cells-derived extracellular vesicles and their contribution to the generation of immune tolerance26
LPS-mediated neutrophil VEGF-A release is modulated by cannabinoid receptor activation26
Follicular helper T cells and follicular regulatory T cells in the immunopathology of primary Sjögren’s syndrome26
CAR NK-92 cells targeting DLL3 kill effectively small cell lung cancer cells in vitro and in vivo26
Tumor inhibition or tumor promotion? The duplicity of CXCR3 in cancer26
Use of integrated metabolomics, transcriptomics, and signal protein profile to characterize the effector function and associated metabotype of polarized macrophage phenotypes25
Mechanisms of NK cell dysfunction in the tumor microenvironment and current clinical approaches to harness NK cell potential for immunotherapy25
Platelet extracellular vesicles in COVID-19: Potential markers and makers25
T follicular helper cells in the humoral immune response to SARS-CoV-2 infection and vaccination25
CCL20 is a novel ligand for the scavenging atypical chemokine receptor 425
Periodontal ligament stem cells in the periodontitis niche: inseparable interactions and mechanisms24
IL-34 and CSF-1, deciphering similarities and differences at steady state and in diseases24
The spleen: “epicenter” in malaria infection and immunity24
Emergence of immunosuppressive LOX-1+ PMN-MDSC in septic shock and severe COVID-19 patients with acute respiratory distress syndrome24
Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis24
Differential expression and regulation of MS4A family members in myeloid cells in physiological and pathological conditions24
Macrophage M1/M2 polarization dynamically adapts to changes in microenvironment and modulates alveolar bone remodeling after dental implantation23
T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death23
Periodontal ligament stem cells promote polarization of M2 macrophages23
MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression23
Melanoma-derived extracellular vesicles skew neutrophils into a pro-tumor phenotype22
Pro-inflammatory polarization primes Macrophages to transition into a distinct M2-like phenotype in response to IL-422
Breakthrough concepts in immune-oncology: Cancer vaccines at the bedside22
Malassezia spp. induce inflammatory cytokines and activate NLRP3 inflammasomes in phagocytes22
HMGB1: An overview of its roles in the pathogenesis of liver disease22
BTK/ITK dual inhibitors: Modulating immunopathology and lymphopenia for COVID-19 therapy22
Regulatory CD4+ and CD8+ T cells are negatively correlated with CD4+/CD8+ T cell ratios in patients acutely infected with SARS-CoV-222
NLRC4 biology in immunity and inflammation21
FOXO3a acetylation regulates PINK1, mitophagy, inflammasome activation in murine palmitate-conditioned and diabetic macrophages21
CD56dimCD57−NKG2C+ NK cells retaining proliferative potential are possible precursors of CD57+NKG2C+ memory-like NK cells21
Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response21
Analysis of deficiency of adenosine deaminase 2 pathogenesis based on single-cell RNA sequencing of monocytes21
Frontline Science: AMPK regulates metabolic reprogramming necessary for interferon production in human plasmacytoid dendritic cells20
IL-38 prevents induction of trained immunity by inhibition of mTOR signaling20
Role of extracellular vesicles in atherosclerosis: An update20
Targeting NLRP3 and Staphylococcal pore-forming toxin receptors in human-induced pluripotent stem cell-derived macrophages19
Frontline Science: Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection19
MiR-155 regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis19
Flow cytometric evaluation of the neutrophil compartment in COVID-19 at hospital presentation: A normal response to an abnormal situation19
Dengue virus-activated platelets modulate monocyte immunometabolic response through lipid droplet biogenesis and cytokine signaling18
IL-17a exacerbates hepatic ischemia–reperfusion injury in fatty liver by promoting neutrophil infiltration and mitochondria-driven apoptosis18
LncRNA SNHG12 alleviates hypertensive vascular endothelial injury through miR-25-3p/SIRT6 pathway18
The imbalance of Th17/Treg via STAT3 activation modulates cognitive impairment inP. gingivalis LPS-induced periodontitis mice18
Anticancer effects of disulfiram in T-cell malignancies through NPL4-mediated ubiquitin–proteasome pathway18
Mismatch between circulating cytokines and spontaneous cytokine production by leukocytes in hyperinflammatory COVID-1918
Scientific premise for the involvement of neutrophil extracellular traps (NETs) in vaccine-induced thrombotic thrombocytopenia (VITT)18
Interplay between alveolar epithelial and dendritic cells and Mycobacterium tuberculosis18
Inhibitory effect of sinomenine on lung cancer cells via negative regulation of α7 nicotinic acetylcholine receptor18
Extracellular vesicles in inflammation: Focus on the microRNA cargo of EVs in modulation of liver diseases18
Novel TREM2 splicing isoform that lacks the V-set immunoglobulin domain is abundant in the human brain17
Aloe emodin relieves Ang II-induced endothelial junction dysfunction via promoting ubiquitination mediated NLRP3 inflammasome inactivation17
The neutrophil subset defined by CD177 expression is preferentially recruited to gingival crevicular fluid in periodontitis17
Histone H4 directly stimulates neutrophil activation through membrane permeabilization17
Immunomodulatory functions of oral mesenchymal stem cells: Novel force for tissue regeneration and disease therapy17
TCF-1 maintains CD8+ T cell stemness in tumor microenvironment17
Plasma extracellular vesicles released after severe burn injury modulate macrophage phenotype and function17
The multiple ways Wnt signaling contributes to acute leukemia pathogenesis17
Functional crosstalk between T cells and monocytes in cancer and atherosclerosis17
Role of vitamin D in regulating COVID-19 severity—An immunological perspective16
The lymphatic drainage system of the CNS plays a role in lymphatic drainage, immunity, and neuroinflammation in stroke16
Sepsis, pyruvate, and mitochondria energy supply chain shortage16
Escape of tumor cells from the NK cell cytotoxic activity16
Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex16
Mendelian diseases of dysregulated canonical NF-κB signaling: From immunodeficiency to inflammation16
Brief review on the roles of neutrophils in cancer development16
Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL2216
Impact of age-, cancer-, and treatment-driven inflammation on T cell function and immunotherapy16
Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells16
Synthesis and identification of lithocholic acid 3-sulfate as RORγt ligand to inhibit Th17 cell differentiation15
LncRNA SNHG8 sponges miR-449c-5p and regulates the SIRT1/FoxO1 pathway to affect microglia activation and blood-brain barrier permeability in ischemic stroke15
At the Bedside: Profiling and treating patients with CXCR4-expressing cancers15
Tensile force transmitted through LFA-1 bonds mechanoregulate neutrophil inflammatory response15
VIP plasma levels associate with survival in severe COVID-19 patients, correlating with protective effects in SARS-CoV-2-infected cells15
Stem cell-like memory T cells: The generation and application15
The regulatory role of insulin in energy metabolism and leukocyte functions15
Macrophage dysfunction in cystic fibrosis: Nature or nurture?15
Frontline Science: Extracellular CIRP generates a proinflammatory Ly6G+CD11bhi subset of low-density neutrophils in sepsis15
Immune modulatory effects of progesterone on oxLDL-induced trained immunity in monocytes15
Diabetes induces macrophage dysfunction through cytoplasmic dsDNA/AIM2 associated pyroptosis15
Characterization of memory T cell subsets and common γ−chain cytokines in convalescent COVID-19 individuals14
The mechanism of Chinese herbal formula HQT in the treatment of rheumatoid arthritis is related to its regulation of lncRNA uc.477 and miR-19b14
Sinomenine increases adenosine A2A receptor and inhibits NF-κB to inhibit arthritis in adjuvant-induced-arthritis rats and fibroblast-like synoviocytes through α7nAChR14
In silico design of a TLR4-mediating multiepitope chimeric vaccine against amyotrophic lateral sclerosis via advanced immunoinformatics14
Neutrophil dysfunction triggers inflammatory bowel disease in G6PC3 deficiency14
GABAergic signaling in human and murine NK cells upon challenge withToxoplasma gondii13
Monocytic myeloid-derived suppressor cells reflect tuberculosis severity and are influenced by cyclooxygenase-2 inhibitors13
Immunopathogenesis of oral submucous fibrosis by chewing the areca nut13
Frontline Science: P2Y11 receptors support T cell activation by directing mitochondrial trafficking to the immune synapse13
The functions of EZH2 in immune cells: Principles for novel immunotherapies13
Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection13
TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies13
Serum-borne lipids amplify TLR-activated inflammatory responses13
Alpha lipoic acid promotes development of hematopoietic progenitors derived from human embryonic stem cells by antagonizing ROS signals13
P2Y12 antagonism results in altered interactions between platelets and regulatory T cells during sepsis13
Gut microbiota shape B cell in health and disease settings12
Research advances in nanomedicine, immunotherapy, and combination therapy for leukemia12
A novel strategy to dissect multifaceted macrophage function in human diseases12
Profiling cellular heterogeneity in asthma with single cell multiparameter CyTOF12
Baicalin protects mice from infection with methicillin-resistant Staphylococcus aureus via alleviating inflammatory response12
The adaptive immune response to Clostridioides difficile: A tricky balance between immunoprotection and immunopathogenesis12
Monocyte subsets predict mortality after cardiac arrest12
Insulin acutely activates metabolism of primary human monocytes and promotes a proinflammatory phenotype12
Innate lymphoid cell and adaptive immune cell cross-talk: A talk meant not to forget12
High infiltration of B cells in tertiary lymphoid structures, TCR oligoclonality, and neoantigens are part of esophageal squamous cell carcinoma microenvironment12
Neutrophil subsets and their differential roles in viral respiratory diseases12
Neuroimmune regulatory networks of the airway mucosa in allergic inflammatory disease12
The role of bacterial DNA containing CpG motifs in diseases12
IL-26 promotes the pathogenesis of malignant pleural effusion by enhancing CD4+IL-22+ T-cell differentiation and inhibiting CD8+ T-cell cytotoxicity12
Emerging neutrophil plasticity: Terminally differentiated cells no more12
Circulating inflammatory cell profiling and periodontitis: A systematic review and meta-analysis12
Serum sphingolipid profile in asthma11
γδ T cell exhaustion: Opportunities for intervention11
Animal models for studies of HIV-1 brain reservoirs11
Neutrophil-derived extracellular vesicles promote feed-forward inflammasome signaling in cystic fibrosis airways11
Human neutrophils activated by TLR8 agonists, with or without IFNγ, synthesize and release EBI3, but not IL-12, IL-27, IL-35, or IL-3911
Annexin A2 regulates unfolded protein response via IRE1–XBP1 axis in macrophages duringP. aeruginosainfection11
Mannan activates tissue native and IgE-sensitized mast cells to proinflammatory response and chemotaxis in TLR4-dependent manner11
Lymphocytes sense antibodies through human FCRL proteins: Emerging roles in mucosal immunity11
Neuroinflammation at single cell level: What is new?11
Immunopathology of chronic critical illness in sepsis survivors: Role of abnormal myelopoiesis11
Hypoxia-inducible factors not only regulate but also are myeloid-cell treatment targets11
The regulation of DOCK family proteins on T and B cells11
Single-cell profiling of T lymphocytes in deficiency of adenosine deaminase 211
Follicular regulatory T cell biology and its role in immune-mediated diseases10
Relationship and prognostic significance of IL-33, PD-1/PD-L1, and tertiary lymphoid structures in cervical cancer10
Differential role of TNFR1 and TNFR2 in the development of imiquimod-induced mouse psoriasis10
Poly(I:C) enhances the efficacy of phagocytosis checkpoint blockade immunotherapy by inducing IL-6 production10
Effects of mesenchymal stromal cell-derived extracellular vesicles in acute respiratory distress syndrome (ARDS): Current understanding and future perspectives10
Myeloid CFTR loss-of-function causes persistent neutrophilic inflammation in cystic fibrosis10
Bone marrow microenvironment drives AML cell OXPHOS addiction and AMPK inhibition to resist chemotherapy10
Inflammasome regulation in driving COVID-19 severity in humans and immune tolerance in bats10
Identification of HLA-A2 restricted CD8+ T cell epitopes in SARS-CoV-2 structural proteins10
The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE-mediated mast cell activation10
A high-calorie diet aggravates LPS-induced pneumonia by disturbing the gut microbiota and Th17/Treg balance10
Metabolic reprogramming of myeloid-derived suppressor cells: An innovative approach confronting challenges10
Classic and new mediators for in vitro modelling of human macrophages10
Stem cells from exfoliated deciduous teeth transplantation ameliorates Sjögren's syndrome by secreting soluble PD-L110
Frontline Science: Conversion of neutrophils into atypical Ly6G+SiglecF+ immune cells with neurosupportive potential in olfactory neuroepithelium10
Interference with long noncoding RNA SNHG3 alleviates cerebral ischemia-reperfusion injury by inhibiting microglial activation10
The effect of an isoquinoline alkaloid on treatment of periodontitis by regulating the neutrophils chemotaxis10
Mechanisms of HIV-1 cell-to-cell transfer to myeloid cells10
Blood tests predict the therapeutic prognosis of anti-PD-1 in advanced biliary tract cancer10
Metabolic and functional impairment of CD8+ T cells from the lungs of influenza-infected obese mice10
K27-linked noncanonic ubiquitination in immune regulation10
Current strategies to induce selective killing of HIV-1-infected cells9
Dickkopf proteins in pathological inflammatory diseases9
Modulation of neutrophil extracellular traps release by Klebsiella pneumoniae9
Tissue-specific murine neutrophil activation states in health and inflammation9
Monoclonal antibodies capable of binding SARS-CoV-2 spike protein receptor-binding motif specifically prevent GM-CSF induction9
Pulmonary and blood dendritic cells from sarcoidosis patients more potently induce IFNγ-producing Th1 cells compared with monocytes9
More than neutrophils: Lin(+)Ly6G(+)IL-5Rα(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes9
Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils9
Neutrophil-derived extracellular vesicles modulate the phenotype of naïve human neutrophils9
A natural oil increases specific anti-OVA IgG levels and induces a cellular immune response combined with aluminum hydroxide9
Treatment with buprenorphine prior to EcoHIV infection of mice prevents the development of neurocognitive impairment9
Microglial activation in Alzheimer's disease: The role of flavonoids and microRNAs9
The cation channel TRPM8 influences the differentiation and function of human monocytes9
Peony seed oil ameliorates neuroinflammation-mediated cognitive deficits by suppressing microglial activation through inhibition of NF-κB pathway in presenilin 1/2 conditional double knockout mice9
Human macrophage polarization shapesB. pertussisintracellular persistence9
Erythrocyte-derived extracellular vesicles aggravate inflammation by promoting the proinflammatory macrophage phenotype through TLR4–MyD88–NF-κB–MAPK pathway9
Divergent Golgi trafficking limits B cell-mediated IgG sialylation9
Adipose-derived stem cell-derived extracellular vesicles inhibit neuroblastoma growth by regulating GABBR1 activity through LINC00622-mediated transcription factor AR9
Iron deprivation restrains the differentiation and pathogenicity of T helper 17 cell9
Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis9
HIV-1-induced type I IFNs promote viral latency in macrophages9
Mechanism of chlorogenic acid in alveolar macrophage polarization in Klebsiella pneumoniae-induced pneumonia9
Frontline Science: The expression of integrin αDβ2 (CD11d/CD18) on neutrophils orchestrates the defense mechanism against endotoxemia and sepsis8
Role of inflammasomes in innate host defense against Entamoeba histolytica8
Shock and kill within the CNS: A promising HIV eradication approach?8
HDAC11 regulates expression of C/EBPβ and immunosuppressive molecules in myeloid-derived suppressor cells8
Modulation of phagocytosis-induced cell death of human neutrophils by Neisseria gonorrhoeae8
Acteoside promotes B cell-derived IL-10 production and ameliorates autoimmunity8
Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections8
IL-17A produced by invariant natural killer T cells and CD3+CD56+αGalcer-CD1d tetramer– T cells promote liver fibrosis in patients with primary biliary cholangitis8
CCDC88B is required for mobility and inflammatory functions of dendritic cells8
Macrophage orchestration of epithelial and stromal cell homeostasis in the intestine8
What a difference ADA2 makes: Insights into the pathophysiology of ADA2 deficiency from single-cell RNA sequencing of monocytes8
Sophoridine inhibits endotoxin-induced acute lung injury by enhancing autophagy of macrophage and reducing inflammation8
Neutrophils vs. amoebas: Immunity against the protozoan parasiteEntamoeba histolytica8
Phenotypes, roles, and modulation of regulatory lymphocytes in periodontitis and its associated systemic diseases8
Sodium houttuyfonate attenuates dextran sulfate sodium associated colitis precolonized withCandida albicansthrough inducing β-glucan exposure8
Structural integrity with functional plasticity: what type I IFN receptor polymorphisms reveal8
Identification of the association between HBcAg-specific T cell and viral control in chronic HBV infection using a cultured ELISPOT assay8
Pan-cancer analysis of GALNTs expression identifies a prognostic of GALNTs feature in low grade glioma8
TGF-β2 interfering oligonucleotides used as adjuvants for microbial vaccines8
A review of signaling and transcriptional control in T follicular helper cell differentiation8
IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge withP. yoelii8
Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-λ3 or IFN-λ4 show distinct phenotypes8
The functional role of surface molecules on extracellular vesicles in cancer, autoimmune diseases, and coagulopathy8
Gift bags from the sentinel cells of the immune system: The diverse role of dendritic cell-derived extracellular vesicles8
Magnetic nanoparticles: A new diagnostic and treatment platform for rheumatoid arthritis8
CCR2-deficient mice are protected to sepsis by the disruption of the inflammatory monocytes emigration from the bone marrow8
Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils8
Role of macrophages in HIV pathogenesis and cure: NIH perspectives8
PRDM1 decreases sensitivity of human NK cells to IL2-induced cell expansion by directly repressing CD25 (IL2RA)8
Treponema denticola stimulates Oncostatin M cytokine release and de novo synthesis in neutrophils and macrophages8
The flavonoids of Sophora flavescens exerts anti-inflammatory activity via promoting autophagy of Bacillus Calmette-Guérin-stimulated macrophages7
Polymorphonuclear myeloid-derived suppressor cells link inflammation and damage response after trauma7
Differential expression of maturation and activation markers on NK cells in patients with active and latent tuberculosis7
Analysis of human neutrophil phenotypes as biomarker to monitor exercise-induced immune changes7
Management of systemic risk factors ahead of dental implant therapy: A beard well lathered is half shaved7
Multifactorial assessment of neutrophil chemotaxis efficiency from a drop of blood7
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