OOIR: Observatory of International Research

Papers

(The TQCC of Genetic Epidemiology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	336
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference	133
Are trait‐associated genes clustered together in a gene network?	65
A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	47
Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	44
	28
Bias and mean squared error in Mendelian randomization with invalid instrumental variables	22
MELODY: Mediation Analysis in Logistic Regression for High‐Dimensional Mediators and a Binary Outcome	19
Statistical power of transcriptome‐wide association studies	16
	15
A Novel One‐Sample Mendelian Randomization Approach for Count‐Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects	15
Adjusting for collider bias in genetic association studies using instrumental variable methods	15
Issue Information	13
	12
Issue Information	12
	12
Gene‐level association analysis of bivariate ordinal traits with functional regressions	11
	11
A Robust Association Test Leveraging Unknown Genetic Interactions: Application to Cystic Fibrosis Lung Disease	10
Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations	10
Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	10
Integrative Harmonization of Phenotypic and Genomic Data Improves Bone Mineral Density Prediction in Multi‐Study Osteoporosis Research	9
Uncovering Ethnicity‐Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family‐Based WGS Analysis	7
Issue Information	7
	6

Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	6
	6
Effect of case and control definitions on genome‐wide association study (GWAS) findings	6
Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	6
Structured testing of genetic association with mixed clinical outcomes	5
Control for population stratification in genetic association studies based on GWAS summary statistics	5
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	5
A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	5
Issue Information	4
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	4
Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	4
	4
Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	4
Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies	4
Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection	4
Correction to “Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations”	4
Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	4
Abstracts	4
Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder	3
Genome‐Wide Association Analyses in Family Triads and Dyads Following Assisted Reproductive Technology	3
simmrd: An open‐source tool to perform simulations in Mendelian randomization	3
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol	3
Dimension Reduction Using Local Principal Components for Regression‐Based Multi‐SNP Analysis in 1000 Genomes and the Canadian Longitudinal Study on Aging (CLSA)	3
Improved two‐step testing of genome‐wide gene–environment interactions	3
Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age	3
Evaluating a Mendelian Risk Prediction Model That Aggregates Across Genes and Cancers	2
Use of genetic correlations to examine selection bias	2
Issue Information	2
Correction to “Abstracts”	2
Sex‐Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome‐Wide Association Study of All of Us and UK Biobank Data	2
Data‐adaptive and pathway‐based tests for association studies between somatic mutations and germline variations in human cancers	2
Using parent‐offspring pairs and trios to estimate indirect genetic effects in education	2
	2
Issue Information	2
Issue Information	2
Comparison of regmed and BayesNetty for exploring causal models with many variables	2
Abstracts	2
Limitation of permutation‐based differential correlation analysis	2
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens	2
Sparse group variable selection for gene–environment interactions in the longitudinal study	2
Cross‐Ancestry Polygenic Prediction: Comparing Methods and Assessing Transferability Across Traits	2
General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals	2
Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank	2
	2
Issue Information	2
Issue Information	2
Bias correction for inverse variance weighting Mendelian randomization	2
	2
The sequence kernel association test for multicategorical outcomes	2