OOIR: Observatory of International Research

Papers

(The TQCC of Genetic Epidemiology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	377
Are trait‐associated genes clustered together in a gene network?	142
Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	52
Outcome and Exposure Polygenic Risk Scores Can Help Reduce Information Bias and Selection Bias in Regression Estimates From Biobank Data	27
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	17
MELODY: Mediation Analysis in Logistic Regression for High‐Dimensional Mediators and a Binary Outcome	16
A Novel One‐Sample Mendelian Randomization Approach for Count‐Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects	16
Issue Information	16
Bias and mean squared error in Mendelian randomization with invalid instrumental variables	15
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Issue Information	12
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Issue Information	11
Integrative Harmonization of Phenotypic and Genomic Data Improves Bone Mineral Density Prediction in Multi‐Study Osteoporosis Research	10
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Gene‐level association analysis of bivariate ordinal traits with functional regressions	7
A Robust Association Test Leveraging Unknown Genetic Interactions: Application to Cystic Fibrosis Lung Disease	7
Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	7
Issue Information	6
Uncovering Ethnicity‐Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family‐Based WGS Analysis	6
Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	6
Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations	6
Effect of case and control definitions on genome‐wide association study (GWAS) findings	6
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	5

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Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	5
Abstracts	4
Structured testing of genetic association with mixed clinical outcomes	4
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Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	4
Issue Information	4
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	4
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A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	4
Correction to “Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations”	4
Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	3
Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	3
Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder	3
Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies	3
simmrd: An open‐source tool to perform simulations in Mendelian randomization	3
Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age	3
Genome‐Wide Association Analyses in Family Triads and Dyads Following Assisted Reproductive Technology	3
Dimension Reduction Using Local Principal Components for Regression‐Based Multi‐SNP Analysis in 1000 Genomes and the Canadian Longitudinal Study on Aging (CLSA)	3
Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank	3
Issue Information	2
Shared and Distinct Genetic Factors Underlying Bile Acid Regulation and Intrahepatic Cholestasis of Pregnancy	2
Issue Information	2
Limitation of permutation‐based differential correlation analysis	2
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens	2
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Use of genetic correlations to examine selection bias	2
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Abstracts	2
Issue Information	2
Sex‐Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome‐Wide Association Study of All of Us and UK Biobank Data	2
Issue Information	2
Bias correction for inverse variance weighting Mendelian randomization	2
Correction to “Abstracts”	2
Improved two‐step testing of genome‐wide gene–environment interactions	2
Comparison of regmed and BayesNetty for exploring causal models with many variables	2
General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals	2
Issue Information	2
Evaluating a Mendelian Risk Prediction Model That Aggregates Across Genes and Cancers	2
Data‐adaptive and pathway‐based tests for association studies between somatic mutations and germline variations in human cancers	2
Using parent‐offspring pairs and trios to estimate indirect genetic effects in education	2
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol	2