Genetic Epidemiology

Article	Citations
Issue Information	171
Revealing genomic heterogeneity and commonality: A penalized integrative analysis approach accounting for the adjacency structure of measurements	67
Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies	39
Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	27
Powerful Rare‐Variant Association Analysis of Secondary Phenotypes	26
PSAP‐Genomic‐Regions: A Method Leveraging Population Data to Prioritize Coding and Non‐Coding Variants in Whole Genome Sequencing for Rare Disease Diagnosis	20
A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	19
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Identifying somatic fingerprints of cancers defined by germline and environmental risk factors	17
Evaluation of saliva as a source of accurate whole‐genome and microbiome sequencing data	17
Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization	16
Adaptive Bayesian variable clustering via structural learning of breast cancer data	15
Are trait‐associated genes clustered together in a gene network?	15
The influence of unmeasured confounding on the MR Steiger approach	14
Gene‐level association analysis of ordinal traits with functional ordinal logistic regressions	12
Comparison of genetic risk prediction models to improve prediction of coronary heart disease in two large cohorts of the MONICA/KORA study	12
Ravages: An R package for the simulation and analysis of rare variants in multicategory phenotypes	10
A novel Mendelian randomization method with binary risk factor and outcome	10
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference	9
Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	9
A Bayesian hierarchically structured prior for gene‐based association testing with multiple traits in genome‐wide association studies	9
Using parent‐offspring pairs and trios to estimate indirect genetic effects in education	9
Sparse group variable selection for gene–environment interactions in the longitudinal study	8
Inverse probability weighting is an effective method to address selection bias during the analysis of high dimensional data	8
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	8

Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals	8
Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	7
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The Translational Machine: A novel machine‐learning approach to illuminate complex genetic architectures	7
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New proposal to address mediation analysis interrogations by using genetic variants as instrumental variables	6
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Abstracts	5
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Refinement of a Published Gene‐Physical Activity Interaction Impacting HDL‐Cholesterol: Role of Sex and Lipoprotein Subfractions	4
Integrative Multi‐Omics Approach for Improving Causal Gene Identification	4
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A Novel One‐Sample Mendelian Randomization Approach for Count‐Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects	4
Comparing Ancestry Standardization Approaches for a Transancestry Colorectal Cancer Polygenic Risk Score	4
Fine‐Mapping the Results From Genome‐Wide Association Studies of Primary Biliary Cholangitis Using SuSiE and h2‐D2	4
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Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model	4
Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	4
Fast and accurate recurrent event analysis for genome‐wide association studies	3
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Benchmarking statistical methods for analyzing parent–child dyads in genetic association studies	3
Testing and estimation of X‐chromosome SNP effects: Impact of model assumptions	3
Genome‐wide association analysis of COVID‐19 mortality risk in SARS‐CoV‐2 genomes identifies mutation in the SARS‐CoV‐2 spike protein that colocalizes with P.1 of the Brazilian strain	3
The eigen higher criticism and eigen Berk–Jones tests for multiple trait association studies based on GWAS summary statistics	3
A two‐sample robust Bayesian Mendelian Randomization method accounting for linkage disequilibrium and idiosyncratic pleiotropy with applications to the COVID‐19 outcomes	3
MR‐BOIL: Causal inference in one‐sample Mendelian randomization for binary outcome with integrated likelihood method	3
DYNATE: Localizing rare‐variant association regions via multiple testing embedded in an aggregation tree	3
Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data	3
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Assisted differential network analysis for gene expression data	3
Bias and mean squared error in Mendelian randomization with invalid instrumental variables	3
FAT4 identified as a potential modifier of orofacial cleft laterality	2
Identifying genes associated with disease outcomes using joint sparse canonical correlation analysis—An application in renal clear cell carcinoma	2
Adjusting for collider bias in genetic association studies using instrumental variable methods	2
Dimension Reduction Using Local Principal Components for Regression‐Based Multi‐SNP Analysis in 1000 Genomes and the Canadian Longitudinal Study on Aging (CLSA)	2
Exploring polygenic‐environment and residual‐environment interactions for depressive symptoms within the UK Biobank	2
Mitigating type 1 error inflation and power loss in GxE PRS: Genotype–environment interaction in polygenic risk score models	2
Including diverse and admixed populations in genetic epidemiology research	2
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Interpreting disease genome‐wide association studies and polygenetic risk scores given eligibility and study design considerations	2
The sequence kernel association test for multicategorical outcomes	2
Shared genetic risk between major orofacial cleft phenotypes in an African population	2
Estimating Causal Effects on a Disease Progression Trait Using Bivariate Mendelian Randomisation	2
Breast and bowel cancers diagnosed in people ‘too young to have cancer’: A blueprint for research using family and twin studies	1
Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age	1

Genome‐wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores	1
Secondary analyses for genome‐wide association studies using expression quantitative trait loci	1
Proteome‐wide association study using cis and trans variants and applied to blood cell and lipid‐related traits in the Women's Health Initiative study	1
Statistical power of transcriptome‐wide association studies	1
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Unveiling challenges in Mendelian randomization for gene–environment interaction	1
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simmrd: An open‐source tool to perform simulations in Mendelian randomization	1
Taking population stratification into account by local permutations in rare‐variant association studies on small samples	1
Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	1
Multitrait transcriptome‐wide association study (TWAS) tests	1
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol	1
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Haplotype reconstruction for genetically complex regions with ambiguous genotype calls: Illustration by the KIR gene region	1
Study of effect modifiers of genetically predicted CETP reduction	1
A fast linkage method for population GWAS cohorts with related individuals	1
Gene‐based association tests in family samples using GWAS summary statistics	1
Hierarchical joint analysis of marginal summary statistics—Part II: High‐dimensional instrumental analysis of omics data	1
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Gene‐level association analysis of bivariate ordinal traits with functional regressions	1
Mediation analysis of multiple mediators with incomplete omics data	1
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REHE: Fast variance components estimation for linear mixed models	1
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Reference‐Based Standardization Approach Stabilizing Small Batch Risk Prediction via Polygenic Score	1
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Transferability of Single‐ and Cross‐Tissue Transcriptome Imputation Models Across Ancestry Groups	0
A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	0
Gene‐environment interaction in type 2 diabetes in Korean cohorts: Interaction of a type 2 diabetes polygenic risk score with triglyceride and cholesterol on fasting glucose levels	0
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A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states	0
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Gene−Air Pollution Interaction and Diversity of Genetic Sampling: The Southern California Children's Health Study	0
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Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations	0
A large‐scale transcriptome‐wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine‐mapping	0
An exploration of linkage fine‐mapping on sequences from case‐control studies	0
General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals	0
Uncertainty Quantification in Epigenetic Clocks via Conformalized Quantile Regression	0
Statistical methods to detect mother–father genetic interaction effects on risk of infertility: A genome‐wide approach	0
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Comparison of regmed and BayesNetty for exploring causal models with many variables	0
Block coordinate descent algorithm improves variable selection and estimation in error‐in‐variables regression	0
Integrating external controls in case–control studies improves power for rare‐variant tests	0
Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data	0
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A novel application of data‐consistent inversion to overcome spurious inference in genome‐wide association studies	0
ioSearch: An approach for identifying interacting multiomics biomarkers using a novel algorithm with application on breast cancer data sets	0
Effect of case and control definitions on genome‐wide association study (GWAS) findings	0
An empirical Bayes approach to improving population‐specific genetic association estimation by leveraging cross‐population data	0
Bayesian multivariant fine mapping using the Laplace prior	0
Sex‐Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome‐Wide Association Study of All of Us and UK Biobank Data	0
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Identifying genetic risk variants associated with brain volumetric phenotypes via K‐sample Ball Divergence method	0
Genome‐wide association study of multiethnic nonsyndromic orofacial cleft families identifies novel loci specific to family and phenotypic subtypes	0
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens	0
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Multi‐marker genetic association and interaction tests with interval‐censored survival outcomes	0
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	0
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Joint analysis of multiple phenotypes for extremely unbalanced case‐control association studies	0
Identifying Disease Associated Multi‐Omics Network With Mixed Graphical Models Based on Markov Random Field Model	0
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Selection bias when inferring the effect direction in Mendelian randomization	0
Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes	0
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Statistical methods for Mendelian models with multiple genes and cancers	0
Genome‐wide association studies of 27 accelerometry‐derived physical activity measurements identified novel loci and genetic mechanisms	0
Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection	0
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	0
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Limitation of permutation‐based differential correlation analysis	0
Sparse prediction informed by genetic annotations using the logit normal prior for Bayesian regression tree ensembles	0
Genetically Predicted Gene Expression Effects on Changes in Red Blood Cell and Plasma Polyunsaturated Fatty Acids	0
Improved two‐step testing of genome‐wide gene–environment interactions	0
A novel transcriptional risk score for risk prediction of complex human diseases	0
Making sense of breast cancer risk estimates	0
Use of genetic correlations to examine selection bias	0
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RoPE: A robust profile likelihood method for differential gene expression analysis	0
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Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes	0
RAVAQ: An integrative pipeline from quality control to region‐based rare variant association analysis	0
The X factor: A robust and powerful approach to X‐chromosome‐inclusive whole‐genome association studies	0
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Efficient identification of trait‐associated loss‐of‐function variants in the UK Biobank cohort by exome‐sequencing based genotype imputation	0
Data‐adaptive and pathway‐based tests for association studies between somatic mutations and germline variations in human cancers	0
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Precisely modeling zero‐inflated count phenotype for rare variants	0
Clarifying the causes of consistent and inconsistent findings in genetics	0
A robust two‐sample transcriptome‐wide Mendelian randomization method integrating GWAS with multi‐tissue eQTL summary statistics	0
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Mendelian randomization in the multivariate general linear model framework	0
Caution against examining the role of reverse causality in Mendelian Randomization	0
A Novel Statistical Method for Unmasking Sex‐Specific Genomics Signatures in Complex Traits	0
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Abstracts	0
Analysis of parent‐of‐origin effects for secondary phenotypes using case–control mother–child pair data	0
Post hoc power is not informative	0
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Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	0
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Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor	0
Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Stu	0
Deep learning identified genetic variants for COVID‐19‐related mortality among 28,097 affected cases in UK Biobank	0
Additional article of this Special Issue was previously published in another issue of Genetic Epidemiology. That is:	0
Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder	0
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Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank	0
Assumptions about frequency‐dependent architectures of complex traits bias measures of functional enrichment	0
Penalized mediation models for multivariate data	0
Predicting Lung Cancer in Korean Never‐Smokers With Polygenic Risk Scores	0
Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis‐multivariable Mendelian randomization to GLP1R gene region	0
Structured testing of genetic association with mixed clinical outcomes	0
Weak and pleiotropy robust sex‐stratified Mendelian randomization in the one sample and two sample settings	0
Exploring and Accounting for Genetically Driven Effect Heterogeneity in Mendelian Randomization	0
Abstracts	0
Interaction between genetics and smoking in determining risk of coronary artery diseases	0
Control for population stratification in genetic association studies based on GWAS summary statistics	0
GWASBrewer: An R Package for Simulating Realistic GWAS Summary Statistics	0
Penalized linear mixed models for structured genetic data	0
Covariate adjusted inference of parent‐of‐origin effects using case–control mother–child paired multilocus genotype data	0
Correction to “Abstracts”	0
Exploring pleiotropy in Mendelian randomisation analyses: What are genetic variants associated with ‘cigarette smoking initiation’ really capturing?	0
Gene–environment interaction analysis via deep learning	0
InTACT: An adaptive and powerful framework for joint‐tissue transcriptome‐wide association studies	0
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Interval estimate of causal effect in summary data based Mendelian randomization in the presence of winner's curse	0
OSCAA: A two‐dimensional Gaussian mixture model for copy number variation association analysis	0
Hierarchical joint analysis of marginal summary statistics—Part I: Multipopulation fine mapping and credible set construction	0
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Random effect based tests for multinomial logistic regression in genetic association studies	0
RetroFun‐RVS: A Retrospective Family‐Based Framework for Rare Variant Analysis Incorporating Functional Annotations	0
Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations	0
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Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	0
Bias correction for inverse variance weighting Mendelian randomization	0
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Collider bias from selecting disease samples distorts causal inferences	0