Genetic Epidemiology

Article	Citations
Bias correction for inverse variance weighting Mendelian randomization	116
Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data	41
The X factor: A robust and powerful approach to X‐chromosome‐inclusive whole‐genome association studies	35
Mendelian randomisation with coarsened exposures	17
Including diverse and admixed populations in genetic epidemiology research	16
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens	15
A robust two‐sample transcriptome‐wide Mendelian randomization method integrating GWAS with multi‐tissue eQTL summary statistics	15
FAT4 identified as a potential modifier of orofacial cleft laterality	15
Caution against examining the role of reverse causality in Mendelian Randomization	14
Post hoc power is not informative	14
Genome‐wide association studies of 27 accelerometry‐derived physical activity measurements identified novel loci and genetic mechanisms	12
Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals	12
Genome‐wide association analysis of COVID‐19 mortality risk in SARS‐CoV‐2 genomes identifies mutation in the SARS‐CoV‐2 spike protein that colocalizes with P.1 of the Brazilian strain	12
Testing and estimation of X‐chromosome SNP effects: Impact of model assumptions	12
Adjusting for collider bias in genetic association studies using instrumental variable methods	11
Multitrait transcriptome‐wide association study (TWAS) tests	10
Multi‐tissue transcriptome‐wide association studies	10
Novel score test to increase power in association test by integrating external controls	9
Inverse probability weighting is an effective method to address selection bias during the analysis of high dimensional data	9
Assumptions about frequency‐dependent architectures of complex traits bias measures of functional enrichment	9
The influence of unmeasured confounding on the MR Steiger approach	9
Incorporating European GWAS findings improve polygenic risk prediction accuracy of breast cancer among East Asians	8
Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization	8
A novel Mendelian randomization method with binary risk factor and outcome	7
Taking population stratification into account by local permutations in rare‐variant association studies on small samples	7

Comparison of genetic risk prediction models to improve prediction of coronary heart disease in two large cohorts of the MONICA/KORA study	7
Statistical power of transcriptome‐wide association studies	7
InTACT: An adaptive and powerful framework for joint‐tissue transcriptome‐wide association studies	6
Genome‐wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores	6
Genome‐wide association study of multiethnic nonsyndromic orofacial cleft families identifies novel loci specific to family and phenotypic subtypes	6
Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection	6
Improved two‐step testing of genome‐wide gene–environment interactions	6
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol	5
Statistical methods with exhaustive search in the identification of gene–gene interactions for colorectal cancer	5
A two‐sample robust Bayesian Mendelian Randomization method accounting for linkage disequilibrium and idiosyncratic pleiotropy with applications to the COVID‐19 outcomes	5
Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes	5
Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes	4
Interaction between genetics and smoking in determining risk of coronary artery diseases	4
Weak and pleiotropy robust sex‐stratified Mendelian randomization in the one sample and two sample settings	4
The eigen higher criticism and eigen Berk–Jones tests for multiple trait association studies based on GWAS summary statistics	4
Clarifying the causes of consistent and inconsistent findings in genetics	4
Block coordinate descent algorithm improves variable selection and estimation in error‐in‐variables regression	4
Penalized linear mixed models for structured genetic data	4
Gene–environment interaction analysis via deep learning	4
A novel transcriptional risk score for risk prediction of complex human diseases	4
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	4
Unsupervised cluster analysis of SARS‐CoV‐2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS‐CoV‐2 virus	4
Random effect based tests for multinomial logistic regression in genetic association studies	3
The utility of the Laplace effect size prior distribution in Bayesian fine‐mapping studies	3
Sparse group variable selection for gene–environment interactions in the longitudinal study	3
A large‐scale transcriptome‐wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine‐mapping	3
Penalized mediation models for multivariate data	3
Joint analysis of multiple phenotypes for extremely unbalanced case‐control association studies	3
Gene‐level association analysis of ordinal traits with functional ordinal logistic regressions	3
Statistical methods for Mendelian models with multiple genes and cancers	3
Deep learning identified genetic variants for COVID‐19‐related mortality among 28,097 affected cases in UK Biobank	3
Efficient identification of trait‐associated loss‐of‐function variants in the UK Biobank cohort by exome‐sequencing based genotype imputation	3
Exploring polygenic‐environment and residual‐environment interactions for depressive symptoms within the UK Biobank	3
Covariate adjusted inference of parent‐of‐origin effects using case–control mother–child paired multilocus genotype data	3
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	2
Integrating external controls in case–control studies improves power for rare‐variant tests	2
Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis‐multivariable Mendelian randomization to GLP1R gene region	2
A fast linkage method for population GWAS cohorts with related individuals	2
Evaluation of saliva as a source of accurate whole‐genome and microbiome sequencing data	2
Gene‐environment interaction in type 2 diabetes in Korean cohorts: Interaction of a type 2 diabetes polygenic risk score with triglyceride and cholesterol on fasting glucose levels	2
Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Stu	2
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Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	2
Multi‐marker genetic association and interaction tests with interval‐censored survival outcomes	2
Variant‐set association test for generalized linear mixed model	2
Assisted estimation of gene expression graphical models	2
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference	2
Mediation analysis of multiple mediators with incomplete omics data	1
Identifying genes associated with disease outcomes using joint sparse canonical correlation analysis—An application in renal clear cell carcinoma	1
Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	1

A Bayesian hierarchically structured prior for gene‐based association testing with multiple traits in genome‐wide association studies	1
The Translational Machine: A novel machine‐learning approach to illuminate complex genetic architectures	1
Gene‐based analysis of bi‐variate survival traits via functional regressions with applications to eye diseases	1
A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states	1
An empirical Bayes approach to improving population‐specific genetic association estimation by leveraging cross‐population data	1
Abstracts	1
REHE: Fast variance components estimation for linear mixed models	1
Benchmarking statistical methods for analyzing parent–child dyads in genetic association studies	1
MR‐BOIL: Causal inference in one‐sample Mendelian randomization for binary outcome with integrated likelihood method	1
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	1
RAVAQ: An integrative pipeline from quality control to region‐based rare variant association analysis	1
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Sparse prediction informed by genetic annotations using the logit normal prior for Bayesian regression tree ensembles	1
Identifying genetic risk variants associated with brain volumetric phenotypes via K‐sample Ball Divergence method	1
Effect of case and control definitions on genome‐wide association study (GWAS) findings	1
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Gene‐level association analysis of bivariate ordinal traits with functional regressions	1
Secondary analyses for genome‐wide association studies using expression quantitative trait loci	1
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Haplotype reconstruction for genetically complex regions with ambiguous genotype calls: Illustration by the KIR gene region	1
New proposal to address mediation analysis interrogations by using genetic variants as instrumental variables	1
RoPE: A robust profile likelihood method for differential gene expression analysis	1
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A Bayesian hierarchically structured prior for rare‐variant association testing	1
Mendelian randomization in the multivariate general linear model framework	1
A unified linear mixed model for familial relatedness and population structure in genetic association studies	1
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A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	0
Identifying somatic fingerprints of cancers defined by germline and environmental risk factors	0
Integrative Multi‐Omics Approach for Improving Causal Gene Identification	0
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Adaptive Bayesian variable clustering via structural learning of breast cancer data	0
Exploring and Accounting for Genetically Driven Effect Heterogeneity in Mendelian Randomization	0
A novel application of data‐consistent inversion to overcome spurious inference in genome‐wide association studies	0
Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model	0
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PSAP‐Genomic‐Regions: A Method Leveraging Population Data to Prioritize Coding and Non‐Coding Variants in Whole Genome Sequencing for Rare Disease Diagnosis	0
Exploring pleiotropy in Mendelian randomisation analyses: What are genetic variants associated with ‘cigarette smoking initiation’ really capturing?	0
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Selection bias when inferring the effect direction in Mendelian randomization	0
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Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor	0
Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	0
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The sequence kernel association test for multicategorical outcomes	0
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Limitation of permutation‐based differential correlation analysis	0
Comparison of regmed and BayesNetty for exploring causal models with many variables	0
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Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data	0
Breast and bowel cancers diagnosed in people ‘too young to have cancer’: A blueprint for research using family and twin studies	0
Bayesian multivariant fine mapping using the Laplace prior	0
DYNATE: Localizing rare‐variant association regions via multiple testing embedded in an aggregation tree	0
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Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	0
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Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations	0
Using parent‐offspring pairs and trios to estimate indirect genetic effects in education	0
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Predicting Lung Cancer in Korean Never‐Smokers With Polygenic Risk Scores	0
Proteome‐wide association study using cis and trans variants and applied to blood cell and lipid‐related traits in the Women's Health Initiative study	0
An exploration of linkage fine‐mapping on sequences from case‐control studies	0
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Shared genetic risk between major orofacial cleft phenotypes in an African population	0
Making sense of breast cancer risk estimates	0
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Use of genetic correlations to examine selection bias	0
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Fine‐Mapping the Results From Genome‐Wide Association Studies of Primary Biliary Cholangitis Using Susie and h2‐D2	0
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Revealing genomic heterogeneity and commonality: A penalized integrative analysis approach accounting for the adjacency structure of measurements	0
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Interpreting disease genome‐wide association studies and polygenetic risk scores given eligibility and study design considerations	0
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Precisely modeling zero‐inflated count phenotype for rare variants	0
Structured testing of genetic association with mixed clinical outcomes	0
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Abstracts	0
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Statistical methods to detect mother–father genetic interaction effects on risk of infertility: A genome‐wide approach	0
Bias and mean squared error in Mendelian randomization with invalid instrumental variables	0
Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder	0
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Hierarchical joint analysis of marginal summary statistics—Part II: High‐dimensional instrumental analysis of omics data	0
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Gene‐based association tests in family samples using GWAS summary statistics	0
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Are trait‐associated genes clustered together in a gene network?	0
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Study of effect modifiers of genetically predicted CETP reduction	0
Correction to “Abstracts”	0
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GWASBrewer: An R Package for Simulating Realistic GWAS Summary Statistics	0
Estimating Causal Effects on a Disease Progression Trait Using Bivariate Mendelian Randomisation	0
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A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	0
Comparing Ancestry Standardization Approaches for a Transancestry Colorectal Cancer Polygenic Risk Score	0
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Powerful Rare‐Variant Association Analysis of Secondary Phenotypes	0
OSCAA: A two‐dimensional Gaussian mixture model for copy number variation association analysis	0
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Interval estimate of causal effect in summary data based Mendelian randomization in the presence of winner's curse	0
Hierarchical joint analysis of marginal summary statistics—Part I: Multipopulation fine mapping and credible set construction	0
Fast and accurate recurrent event analysis for genome‐wide association studies	0
ioSearch: An approach for identifying interacting multiomics biomarkers using a novel algorithm with application on breast cancer data sets	0
Collider bias from selecting disease samples distorts causal inferences	0
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Assisted differential network analysis for gene expression data	0
Control for population stratification in genetic association studies based on GWAS summary statistics	0
Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	0
Data‐adaptive and pathway‐based tests for association studies between somatic mutations and germline variations in human cancers	0
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Mitigating type 1 error inflation and power loss in GxE PRS: Genotype–environment interaction in polygenic risk score models	0
Unveiling challenges in Mendelian randomization for gene–environment interaction	0
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Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	0
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Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	0
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Analysis of parent‐of‐origin effects for secondary phenotypes using case–control mother–child pair data	0
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simmrd: An open‐source tool to perform simulations in Mendelian randomization	0
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Ravages: An R package for the simulation and analysis of rare variants in multicategory phenotypes	0