Genetic Epidemiology

Article	Citations
	224
Are trait‐associated genes clustered together in a gene network?	89
Gene‐level association analysis of ordinal traits with functional ordinal logistic regressions	36
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	35
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference	29
A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	20
Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	20
Bias and mean squared error in Mendelian randomization with invalid instrumental variables	19
The eigen higher criticism and eigen Berk–Jones tests for multiple trait association studies based on GWAS summary statistics	13
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A two‐sample robust Bayesian Mendelian Randomization method accounting for linkage disequilibrium and idiosyncratic pleiotropy with applications to the COVID‐19 outcomes	12
Statistical power of transcriptome‐wide association studies	12
Adjusting for collider bias in genetic association studies using instrumental variable methods	11
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A Novel One‐Sample Mendelian Randomization Approach for Count‐Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects	10
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Gene‐level association analysis of bivariate ordinal traits with functional regressions	8
Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	8
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A Robust Association Test Leveraging Unknown Genetic Interactions: Application to Cystic Fibrosis Lung Disease	7
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Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	6
Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations	6

Genome‐wide association studies of 27 accelerometry‐derived physical activity measurements identified novel loci and genetic mechanisms	6
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Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	5
Integrating external controls in case–control studies improves power for rare‐variant tests	5
Uncovering Ethnicity‐Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family‐Based WGS Analysis	5
Genome‐wide association study of multiethnic nonsyndromic orofacial cleft families identifies novel loci specific to family and phenotypic subtypes	5
Gene‐environment interaction in type 2 diabetes in Korean cohorts: Interaction of a type 2 diabetes polygenic risk score with triglyceride and cholesterol on fasting glucose levels	5
Collider bias from selecting disease samples distorts causal inferences	5
Effect of case and control definitions on genome‐wide association study (GWAS) findings	5
A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	4
Covariate adjusted inference of parent‐of‐origin effects using case–control mother–child paired multilocus genotype data	4
Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	4
Control for population stratification in genetic association studies based on GWAS summary statistics	4
Structured testing of genetic association with mixed clinical outcomes	4
Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	3
Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies	3
Genome‐Wide Association Analyses in Family Triads and Dyads Following Assisted Reproductive Technology	3
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Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection	3
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	3
Exploring polygenic‐environment and residual‐environment interactions for depressive symptoms within the UK Biobank	3
The influence of unmeasured confounding on the MR Steiger approach	3
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Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	3
Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	3
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Genome‐wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores	2
simmrd: An open‐source tool to perform simulations in Mendelian randomization	2
Improved two‐step testing of genome‐wide gene–environment interactions	2
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Dimension Reduction Using Local Principal Components for Regression‐Based Multi‐SNP Analysis in 1000 Genomes and the Canadian Longitudinal Study on Aging (CLSA)	2
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol	2
Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank	2
Comparison of regmed and BayesNetty for exploring causal models with many variables	2
Correction to “Abstracts”	2
Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age	2
REHE: Fast variance components estimation for linear mixed models	2
Use of genetic correlations to examine selection bias	2
General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals	2
Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder	2
Fine‐Mapping the Results From Genome‐Wide Association Studies of Primary Biliary Cholangitis Using SuSiE and h2‐D2	1
Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor	1
The sequence kernel association test for multicategorical outcomes	1
Selection bias when inferring the effect direction in Mendelian randomization	1
Limitation of permutation‐based differential correlation analysis	1
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OSCAA: A two‐dimensional Gaussian mixture model for copy number variation association analysis	1
Estimating Causal Effects on a Disease Progression Trait Using Bivariate Mendelian Randomisation	1

Taking population stratification into account by local permutations in rare‐variant association studies on small samples	1
Exploring Similarities and Differences Between Methods That Exploit Patterns of Local Genetic Correlation to Identify Shared Causal Loci Through Application to Genome‐Wide Association Studies of Multi	1
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Random effect based tests for multinomial logistic regression in genetic association studies	1
Bias correction for inverse variance weighting Mendelian randomization	1
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Data‐adaptive and pathway‐based tests for association studies between somatic mutations and germline variations in human cancers	1
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Penalized mediation models for multivariate data	1
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Using parent‐offspring pairs and trios to estimate indirect genetic effects in education	1
Sparse group variable selection for gene–environment interactions in the longitudinal study	1
An exploration of linkage fine‐mapping on sequences from case‐control studies	1
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Genome‐Wide Association Studies of Down Syndrome Associated Congenital Heart Defects Suggests a Genetically Heterogeneous Risk for CHD in DS	1
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Sex‐Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome‐Wide Association Study of All of Us and UK Biobank Data	1
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens	1
Gene−Air Pollution Interaction and Diversity of Genetic Sampling: The Southern California Children's Health Study	1
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A fast linkage method for population GWAS cohorts with related individuals	0
Reference‐Based Standardization Approach Stabilizing Small Batch Risk Prediction via Polygenic Score	0
Hierarchical joint analysis of marginal summary statistics—Part II: High‐dimensional instrumental analysis of omics data	0
Clarifying the causes of consistent and inconsistent findings in genetics	0
Integrative Multi‐Omics Approach for Improving Causal Gene Identification	0
Revealing genomic heterogeneity and commonality: A penalized integrative analysis approach accounting for the adjacency structure of measurements	0
Identity‐By‐Descent Mapping Using Multi‐Individual IBD With Genome‐Wide Multiple Testing Adjustment	0
Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes	0
Joint analysis of multiple phenotypes for extremely unbalanced case‐control association studies	0
Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data	0
Bayesian multivariant fine mapping using the Laplace prior	0
Mendelian randomization in the multivariate general linear model framework	0
Multi‐marker genetic association and interaction tests with interval‐censored survival outcomes	0
Comparing Ancestry Standardization Approaches for a Transancestry Colorectal Cancer Polygenic Risk Score	0
Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations	0
PSAP‐Genomic‐Regions: A Method Leveraging Population Data to Prioritize Coding and Non‐Coding Variants in Whole Genome Sequencing for Rare Disease Diagnosis	0
Transferability of Single‐ and Cross‐Tissue Transcriptome Imputation Models Across Ancestry Groups	0
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Making sense of breast cancer risk estimates	0
Hierarchical joint analysis of marginal summary statistics—Part I: Multipopulation fine mapping and credible set construction	0
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Exploring pleiotropy in Mendelian randomisation analyses: What are genetic variants associated with ‘cigarette smoking initiation’ really capturing?	0
A Bayesian hierarchically structured prior for gene‐based association testing with multiple traits in genome‐wide association studies	0
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RoPE: A robust profile likelihood method for differential gene expression analysis	0
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An empirical Bayes approach to improving population‐specific genetic association estimation by leveraging cross‐population data	0
Genetically Predicted Gene Expression Effects on Changes in Red Blood Cell and Plasma Polyunsaturated Fatty Acids	0
A Novel Statistical Method for Unmasking Sex‐Specific Genomics Signatures in Complex Traits	0
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Deep learning identified genetic variants for COVID‐19‐related mortality among 28,097 affected cases in UK Biobank	0
Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes	0
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Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization	0
Post hoc power is not informative	0
Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model	0
Shared genetic risk between major orofacial cleft phenotypes in an African population	0
Analysis of parent‐of‐origin effects for secondary phenotypes using case–control mother–child pair data	0
Mediation analysis of multiple mediators with incomplete omics data	0
Gene‐based association tests in family samples using GWAS summary statistics	0
Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data	0
Identifying genes associated with disease outcomes using joint sparse canonical correlation analysis—An application in renal clear cell carcinoma	0
Study of effect modifiers of genetically predicted CETP reduction	0
Three Loci Affecting Variance of Body Mass Index in African Americans and Sub‐Saharan Africans	0
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Efficient identification of trait‐associated loss‐of‐function variants in the UK Biobank cohort by exome‐sequencing based genotype imputation	0
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Interpreting disease genome‐wide association studies and polygenetic risk scores given eligibility and study design considerations	0
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Additional article of this Special Issue was previously published in another issue of Genetic Epidemiology. That is:	0
Weak and pleiotropy robust sex‐stratified Mendelian randomization in the one sample and two sample settings	0
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Proteome‐wide association study using cis and trans variants and applied to blood cell and lipid‐related traits in the Women's Health Initiative study	0
Sparse prediction informed by genetic annotations using the logit normal prior for Bayesian regression tree ensembles	0
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Precisely modeling zero‐inflated count phenotype for rare variants	0
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GWASBrewer: An R Package for Simulating Realistic GWAS Summary Statistics	0
Ravages: An R package for the simulation and analysis of rare variants in multicategory phenotypes	0
Powerful Rare‐Variant Association Analysis of Secondary Phenotypes	0
Gene–environment interaction analysis via deep learning	0
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Block coordinate descent algorithm improves variable selection and estimation in error‐in‐variables regression	0
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Statistical methods for Mendelian models with multiple genes and cancers	0
Haplotype reconstruction for genetically complex regions with ambiguous genotype calls: Illustration by the KIR gene region	0
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Refinement of a Published Gene‐Physical Activity Interaction Impacting HDL‐Cholesterol: Role of Sex and Lipoprotein Subfractions	0
Fast and accurate recurrent event analysis for genome‐wide association studies	0
A novel application of data‐consistent inversion to overcome spurious inference in genome‐wide association studies	0
Secondary analyses for genome‐wide association studies using expression quantitative trait loci	0
Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis‐multivariable Mendelian randomization to GLP1R gene region	0
MR‐BOIL: Causal inference in one‐sample Mendelian randomization for binary outcome with integrated likelihood method	0
Breast and bowel cancers diagnosed in people ‘too young to have cancer’: A blueprint for research using family and twin studies	0
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Interaction between genetics and smoking in determining risk of coronary artery diseases	0
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Statistical methods to detect mother–father genetic interaction effects on risk of infertility: A genome‐wide approach	0
Interval estimate of causal effect in summary data based Mendelian randomization in the presence of winner's curse	0
Exploring and Accounting for Genetically Driven Effect Heterogeneity in Mendelian Randomization	0
Including diverse and admixed populations in genetic epidemiology research	0
RAVAQ: An integrative pipeline from quality control to region‐based rare variant association analysis	0
Predicting Lung Cancer in Korean Never‐Smokers With Polygenic Risk Scores	0
Identifying Disease Associated Multi‐Omics Network With Mixed Graphical Models Based on Markov Random Field Model	0
Unveiling challenges in Mendelian randomization for gene–environment interaction	0
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Uncertainty Quantification in Epigenetic Clocks via Conformalized Quantile Regression	0
A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states	0
Adaptive Bayesian variable clustering via structural learning of breast cancer data	0
A large‐scale transcriptome‐wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine‐mapping	0
Benchmarking statistical methods for analyzing parent–child dyads in genetic association studies	0
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Identifying somatic fingerprints of cancers defined by germline and environmental risk factors	0
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ioSearch: An approach for identifying interacting multiomics biomarkers using a novel algorithm with application on breast cancer data sets	0
RetroFun‐RVS: A Retrospective Family‐Based Framework for Rare Variant Analysis Incorporating Functional Annotations	0
DYNATE: Localizing rare‐variant association regions via multiple testing embedded in an aggregation tree	0
New proposal to address mediation analysis interrogations by using genetic variants as instrumental variables	0
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Mitigating type 1 error inflation and power loss in GxE PRS: Genotype–environment interaction in polygenic risk score models	0
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