Genetic Epidemiology

Article	Citations
A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects	336
Deconvolution analysis of cell‐type expression from bulk tissues by integrating with single‐cell expression reference	133
Are trait‐associated genes clustered together in a gene network?	65
A Brief History behind the journal Genetic Epidemiology and the International Genetic Epidemiology Society	47
Statistics to prioritize rare variants in family‐based sequencing studies with disease subtypes	44
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Bias and mean squared error in Mendelian randomization with invalid instrumental variables	22
MELODY: Mediation Analysis in Logistic Regression for High‐Dimensional Mediators and a Binary Outcome	19
Statistical power of transcriptome‐wide association studies	16
A Novel One‐Sample Mendelian Randomization Approach for Count‐Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects	15
Adjusting for collider bias in genetic association studies using instrumental variable methods	15
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Gene‐level association analysis of bivariate ordinal traits with functional regressions	11
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A Robust Association Test Leveraging Unknown Genetic Interactions: Application to Cystic Fibrosis Lung Disease	10
Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations	10
Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses	10
Integrative Harmonization of Phenotypic and Genomic Data Improves Bone Mineral Density Prediction in Multi‐Study Osteoporosis Research	9
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Uncovering Ethnicity‐Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family‐Based WGS Analysis	7
Sensitivity analyses gain relevance by fixing parameters observable during the empirical analyses	6

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Effect of case and control definitions on genome‐wide association study (GWAS) findings	6
Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries	6
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Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits	5
A Mixed‐Effect Kernel Machine Regression Model for Integrative Analysis of Alpha Diversity in Microbiome Studies	5
Structured testing of genetic association with mixed clinical outcomes	5
Control for population stratification in genetic association studies based on GWAS summary statistics	5
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Phenotypic variance partitioning by transcriptomic gene expression levels and environmental variables for anthropometric traits using GTEx data	4
Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies	4
Novel HLA associations with outcomes of Mycobacterium tuberculosis exposure and sarcoidosis in individuals of African ancestry using nearest‐neighbor feature selection	4
Correction to “Multivariable MR Can Mitigate Bias in Two‐Sample MR Using Covariable‐Adjusted Summary Associations”	4
Meta‐analysis of breast cancer risk for individuals with PALB2 pathogenic variants	4
Abstracts	4
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Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons	4
Ethical, Legal, and Social Implications of Gene‐Environment Interaction Research	4
Genome‐Wide Association Analyses in Family Triads and Dyads Following Assisted Reproductive Technology	3
simmrd: An open‐source tool to perform simulations in Mendelian randomization	3
Statistical learning for sparser fine‐mapped polygenic models: The prediction of LDL‐cholesterol	3
Dimension Reduction Using Local Principal Components for Regression‐Based Multi‐SNP Analysis in 1000 Genomes and the Canadian Longitudinal Study on Aging (CLSA)	3
Improved two‐step testing of genome‐wide gene–environment interactions	3
Parent‐of‐Origin Effects in Childhood Asthma at Seven Years of Age	3
Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder	3
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Comparison of regmed and BayesNetty for exploring causal models with many variables	2
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Limitation of permutation‐based differential correlation analysis	2
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens	2
Sparse group variable selection for gene–environment interactions in the longitudinal study	2
Cross‐Ancestry Polygenic Prediction: Comparing Methods and Assessing Transferability Across Traits	2
General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals	2
Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank	2
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Bias correction for inverse variance weighting Mendelian randomization	2
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The sequence kernel association test for multicategorical outcomes	2
Evaluating a Mendelian Risk Prediction Model That Aggregates Across Genes and Cancers	2
Use of genetic correlations to examine selection bias	2
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Correction to “Abstracts”	2
Sex‐Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome‐Wide Association Study of All of Us and UK Biobank Data	2
Data‐adaptive and pathway‐based tests for association studies between somatic mutations and germline variations in human cancers	2
Using parent‐offspring pairs and trios to estimate indirect genetic effects in education	2
Genome‐Wide Association Studies of Down Syndrome Associated Congenital Heart Defects Suggests a Genetically Heterogeneous Risk for CHD in DS	1

Gene−Air Pollution Interaction and Diversity of Genetic Sampling: The Southern California Children's Health Study	1
Statistical methods to detect mother–father genetic interaction effects on risk of infertility: A genome‐wide approach	1
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Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations	1
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An exploration of linkage fine‐mapping on sequences from case‐control studies	1
Methods for Prioritizing Causal Genes in Molecular Studies of Human Disease: The State of the Art	1
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Bayesian multivariant fine mapping using the Laplace prior	1
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Selection bias when inferring the effect direction in Mendelian randomization	1
Fine‐Mapping the Results From Genome‐Wide Association Studies of Primary Biliary Cholangitis Using SuSiE and h2‐D2	1
Exploring Similarities and Differences Between Methods That Exploit Patterns of Local Genetic Correlation to Identify Shared Causal Loci Through Application to Genome‐Wide Association Studies of Multi	1
Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor	1
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The Importance of Sensitivity Analyses for the MR Steiger Approach	1
OSCAA: A two‐dimensional Gaussian mixture model for copy number variation association analysis	1
A Linear Mixed Model With Measurement Error Correction (LMM‐MEC): A Method for Summary‐Data‐Based Multivariable Mendelian Randomization	1
Estimating Causal Effects on a Disease Progression Trait Using Bivariate Mendelian Randomisation	1
Deep learning identified genetic variants for COVID‐19‐related mortality among 28,097 affected cases in UK Biobank	0
Statistical methods for Mendelian models with multiple genes and cancers	0
Clarifying the causes of consistent and inconsistent findings in genetics	0
Mitigating type 1 error inflation and power loss in GxE PRS: Genotype–environment interaction in polygenic risk score models	0
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Mediation analysis of multiple mediators with incomplete omics data	0
A novel application of data‐consistent inversion to overcome spurious inference in genome‐wide association studies	0
Transferability of Single‐ and Cross‐Tissue Transcriptome Imputation Models Across Ancestry Groups	0
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Including diverse and admixed populations in genetic epidemiology research	0
Shared genetic risk between major orofacial cleft phenotypes in an African population	0
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Exploring pleiotropy in Mendelian randomisation analyses: What are genetic variants associated with ‘cigarette smoking initiation’ really capturing?	0
Gene‐based association tests in family samples using GWAS summary statistics	0
Powerful Rare‐Variant Association Analysis of Secondary Phenotypes	0
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Study of effect modifiers of genetically predicted CETP reduction	0
Comparing Ancestry Standardization Approaches for a Transancestry Colorectal Cancer Polygenic Risk Score	0
Interpreting disease genome‐wide association studies and polygenetic risk scores given eligibility and study design considerations	0
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Proteome‐wide association study using cis and trans variants and applied to blood cell and lipid‐related traits in the Women's Health Initiative study	0
Post hoc power is not informative	0
Identifying Disease Associated Multi‐Omics Network With Mixed Graphical Models Based on Markov Random Field Model	0
Unveiling challenges in Mendelian randomization for gene–environment interaction	0
Making sense of breast cancer risk estimates	0
Adaptive Bayesian variable clustering via structural learning of breast cancer data	0
Genetically Predicted Gene Expression Effects on Changes in Red Blood Cell and Plasma Polyunsaturated Fatty Acids	0
Ravages: An R package for the simulation and analysis of rare variants in multicategory phenotypes	0
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Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data	0
Three Loci Affecting Variance of Body Mass Index in African Americans and Sub‐Saharan Africans	0
Weak and pleiotropy robust sex‐stratified Mendelian randomization in the one sample and two sample settings	0
Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model	0
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Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes	0
Variant Classification Using Proteomics‐Informed Large Language Models Increases Power of Rare Variant Association Studies and Enhances Target Discovery	0
Associations of Herpes Simplex Virus Type 1/2 IgG Seropositivity and Arthritis Subtypes: Integrating Cross‐Sectional Epidemiology and Genetic Association Analyses	0
Hierarchical joint analysis of marginal summary statistics—Part I: Multipopulation fine mapping and credible set construction	0
Hierarchical joint analysis of marginal summary statistics—Part II: High‐dimensional instrumental analysis of omics data	0
Exploring Random Forest in Genetic Risk Score Construction	0
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Adjustment for Genotype Imputation Uncertainty Corrects for Inflated Type I Error in Family‐Based Association Testing	0
Interval estimate of causal effect in summary data based Mendelian randomization in the presence of winner's curse	0
Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization	0
An empirical Bayes approach to improving population‐specific genetic association estimation by leveraging cross‐population data	0
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Large‐Scale Genotype‐Based Trait Imputation With Multi‐Ancestry GWAS Data	0
DYNATE: Localizing rare‐variant association regions via multiple testing embedded in an aggregation tree	0
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Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis‐multivariable Mendelian randomization to GLP1R gene region	0
Predicting Lung Cancer in Korean Never‐Smokers With Polygenic Risk Scores	0
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Reference‐Based Standardization Approach Stabilizing Small Batch Risk Prediction via Polygenic Score	0
MR‐BOIL: Causal inference in one‐sample Mendelian randomization for binary outcome with integrated likelihood method	0
RoPE: A robust profile likelihood method for differential gene expression analysis	0
Revealing genomic heterogeneity and commonality: A penalized integrative analysis approach accounting for the adjacency structure of measurements	0
Fast and accurate recurrent event analysis for genome‐wide association studies	0

Moderating the Heritability of Body Mass Index by Age and Sex With Genomic Data	0
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Exploring and Accounting for Genetically Driven Effect Heterogeneity in Mendelian Randomization	0
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A Novel Statistical Method for Unmasking Sex‐Specific Genomics Signatures in Complex Traits	0
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PSAP‐Genomic‐Regions: A Method Leveraging Population Data to Prioritize Coding and Non‐Coding Variants in Whole Genome Sequencing for Rare Disease Diagnosis	0
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Identifying genes associated with disease outcomes using joint sparse canonical correlation analysis—An application in renal clear cell carcinoma	0
The Complex Relationship of Genetic Ancestry With Self‐Reported Race/Ethnicity	0
RetroFun‐RVS: A Retrospective Family‐Based Framework for Rare Variant Analysis Incorporating Functional Annotations	0
Gene–environment interaction analysis via deep learning	0
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Identifying Causal Genotype–Phenotype Relationships for Population‐Sampled Parent–Child Trios	0
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Variant Prioritization by Pedigree‐Based Haplotyping	0
New proposal to address mediation analysis interrogations by using genetic variants as instrumental variables	0
Identity‐By‐Descent Mapping Using Multi‐Individual IBD With Genome‐Wide Multiple Testing Adjustment	0
Correcting for Genomic Inflation Leads to Loss of Power in Large‐Scale Genome‐Wide Association Study Meta‐Analysis	0
Archipelago Method for Variant Set Association Test Statistics	0
Joint analysis of multiple phenotypes for extremely unbalanced case‐control association studies	0
Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data	0
A fast linkage method for population GWAS cohorts with related individuals	0
Additional article of this Special Issue was previously published in another issue of Genetic Epidemiology. That is:	0
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Breast and bowel cancers diagnosed in people ‘too young to have cancer’: A blueprint for research using family and twin studies	0
Integrative Multi‐Omics Approach for Improving Causal Gene Identification	0
A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states	0
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Sparse prediction informed by genetic annotations using the logit normal prior for Bayesian regression tree ensembles	0
Efficient identification of trait‐associated loss‐of‐function variants in the UK Biobank cohort by exome‐sequencing based genotype imputation	0
Uncertainty Quantification in Epigenetic Clocks via Conformalized Quantile Regression	0
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Extending the Use of Mendelian Randomisation With Non‐Inherited Variants to Assess Socially Transmitted Parental Exposures Under Assortative Mating	0
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GWASBrewer: An R Package for Simulating Realistic GWAS Summary Statistics	0
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Analysis of parent‐of‐origin effects for secondary phenotypes using case–control mother–child pair data	0
Refinement of a Published Gene‐Physical Activity Interaction Impacting HDL‐Cholesterol: Role of Sex and Lipoprotein Subfractions	0
ioSearch: An approach for identifying interacting multiomics biomarkers using a novel algorithm with application on breast cancer data sets	0
Identifying somatic fingerprints of cancers defined by germline and environmental risk factors	0
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Haplotype reconstruction for genetically complex regions with ambiguous genotype calls: Illustration by the KIR gene region	0