OOIR: Observatory of International Research

Papers

(The TQCC of Critical Reviews in Biotechnology is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Elucidation of transfer RNAs as stress regulating agents and the experimental strategies to conceive the functional role of tRNA-derived fragments in plants	135
Overview of resveratrol properties, applications, and advances in microbial precision fermentation	127
Unveiling the potential of dendrobine: insights into bioproduction, bioactivities, safety, circular economy, and future prospects	87
Recent updates on green synthesis of lignin nanoparticle and its potential applications in modern biotechnology	85
Sustainability of biodegradable plastics: a review on social, economic, and environmental factors	76
Advances in the development of phage-mediated cyanobacterial cell lysis	76
Plant lipid phosphate phosphatases: current advances and future outlooks	62
Wastewater-borne viruses and bacteria, surveillance and biosensors at the interface of academia and field deployment	60
Sustainable utilization of fruit and vegetable waste bioresources for bioplastics production	59
Yarrowia lipolytica as a biorefinery platform for effluents and solid wastes valorization – challenges and opportunities	57
Electrospun wound dressings with antibacterial function: a critical review of plant extract and essential oil incorporation	56
Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites	54
Enzyme hybrid nanoflowers and enzyme@metal–organic frameworks composites: fascinating hybrid nanobiocatalysts	52
Smart reprograming of plants against salinity stress using modern biotechnological tools	51
Potential use of gene drive modified insects against disease vectors, agricultural pests and invasive species poses new challenges for risk assessment	50
Advances in production of high-value lipids by oleaginous yeasts	47
Advances in the metabolic engineering of Saccharomyces cerevisiae and Yarrowia lipolytica for the production of β	45
Biological and biorational management of blast diseases in cereals caused by Magnaporthe oryzae	44
Fermentation strategies to improve propionic acid production withpropionibacteriumssp.: a review	43
Neurodegenerative disorders management: state-of-art and prospects of nano-biotechnology	43
Advances in high-throughput screening approaches for biosurfactants: current trends, bottlenecks and perspectives	41
Recent development of phenyllactic acid: physicochemical properties, biotechnological production strategies and applications	40
Synthetic biology for the food industry: advances and challenges	40
3D printing: trends and approaches toward achieving long-term sustainability in the food industry	39
Diversity of fungus-mediated synthesis of gold nanoparticles: properties, mechanisms, challenges, and solving methods	39

Biomaterials for eco-friendly packaging in dairy products: towards a cleaner, greener, and sustainable future	39
Role of proteins in the biosynthesis and functioning of metallic nanoparticles	38
Bacterial genome reduction for optimal chassis of synthetic biology: a review	38
Production and waste treatment of polyesters: application of bioresources and biotechniques	37
Enhancing plastic biodegradation process: strategies and opportunities	37
Biofilm formation in xenobiotic-degrading microorganisms	36
Antimicrobials from endophytes as novel therapeutics to counter drug-resistant pathogens	36
Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications	35
Harnessing microbial division of labor for biomanufacturing: a review of laboratory and formal modeling approaches	35
Cold-active enzymes from deep marine psychrophiles: harnessing their potential in enhanced food production and sustainability	35
A close-up of regulatory networks and signaling pathways of MKK5 in biotic and abiotic stresses	35
Current trends in solid tannery waste management	34
A crosswalk on the genetic and conventional strategies for enhancing astaxanthin production in Haematococcus pluvialis	34
Proteomics for abiotic stresses in legumes: present status and future directions	33
Marine algal flavonoids and phlorotannins; an intriguing frontier of biofunctional secondary metabolites	32
Unveiling the silent defenders: mycobacterial stress sensors at the forefront to combat tuberculosis	32
Pluripotent stem cells for skeletal tissue engineering	31
Advances in sustainable approaches utilizing orange peel waste to produce highly value-added bioproducts	31
Field and laboratory guidelines for reliable bioinformatic and statistical analysis of bacterial shotgun metagenomic data	31
Improving environmental stress resilience in crops by genome editing: insights from extremophile plants	31
Available strategies for improving the biosynthesis of surfactin: a review	30
Critical analysis of analytical techniques developed for statins in biological fluids, environmental and fermentation samples	30
Crucial aspects of metabolism and cell biology relating to industrial production and processing of Saccharomyces biomass	30
A story of two kingdoms: unravelling the intricacies of protein phase separation in plants and animals	29
Systems seed biology to understand and manipulate rice grain quality and nutrition	29
Microbial cell factories using Paenibacillus : status and perspectives	28
Recent trends in nanomaterial-based signal amplification in electrochemical aptasensors	28
Synergetic anaerobic digestion of food waste for enhanced production of biogas and value-added products: strategies, challenges, and techno-economic analysis	28
Amylases from thermophilic bacteria: structure and function relationship	28
Molecular modification and biotechnological applications of microbial aspartic proteases	27
New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma	27
Amplification-free nucleic acids detection with next-generation CRISPR/dx systems	25
D-allulose 3-epimerase for low-calorie D-allulose synthesis: microbial production, characterization, and applications	25
Insights into organic loading rates of anaerobic digestion for biogas production: a review	25
Strategies to improve the efficiency and quality of mutant breeding using heavy-ion beam irradiation	24
Research progress on the application of cell-free synthesis systems for enzymatic processes	24
Catalytic mechanisms underlying fungal fatty acid desaturases activities	24
Optimum chalcone synthase for flavonoid biosynthesis in microorganisms	24
A comprehensive review on tissue culture studies and secondary metabolite production in Bacopa monnieri L. Pennell: a nootropic plant	24
Membrane bioreactors for syngas permeation and fermentation	24
Nanobiosensors and their role in detection of adulterants and contaminants in food products	24
Co-culturing microbial consortia: approaches for applications in biomanufacturing and bioprocessing	24
Emerging trends in high-solids enzymatic saccharification of lignocellulosic feedstocks for developing an efficient and industrially deployable sugar platform	23
How do probiotics alleviate constipation? A narrative review of mechanisms	23
A review on biomass-derived levulinic acid for application in drug synthesis	23
Value-added biotransformation of agricultural byproducts by cellulolytic fungi: a review	23
Thraustochytrids as a promising source of fatty acids, carotenoids, and sterols: bioactive compound biosynthesis, and modern biotechnology	23
Fashion meets science: how advanced breeding approaches could revolutionize the textile industry	23
Microbial alchemy: upcycling of brewery spent grains into high-value products through fermentation	22
Extension characteristics of TdT and its application in biosensors	22

Microbial production of vitamin B5: current status and prospects	22
Engineering industrial yeast for improved tolerance and robustness	20
APETALA2/ethylene-responsive factors in higher plant and their roles in regulation of plant stress response	20
Efficient heterologous expression of cytochrome P450 enzymes in microorganisms for the biosynthesis of natural products	20